| Enzyme classes:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 General information:
 
 
 
 
 
 | EC 4.1.3, Oxo- Acid- Lyases, or aldolases that catalyze the cleavage of a 3- hydroxy acid 
 
 EC 4.1.3 sub-subclass definitionEC 4.1.3 sub-subclass contains Oxo-Acid-Lyases, or aldolases that catalyze the cleavage of a 3-hydroxy acid. IUBMB Enzyme Nomenclature. Many enzymes from this sub-subclass are reclassified as synthases.Members of EC 4.1.3 sub-subclass EC 4.1.3.1 - isocitrate glyoxylate-lyase (succinate-forming)EC 4.1.3.2 - obsolete, reclassified now as malate synthase, EC 2.3.3.9EC 4.1.3.3 - N-acetylneuraminate pyruvate-lyase  (N-acetyl-D-mannosamine-forming)EC 4.1.3.4 - (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)EC 4.1.3.5 - obsolete, reclassified now as hydroxymethylglutaryl-CoA synthase, EC 2.3.3.10EC 4.1.3.6 - citrate oxaloacetate-lyase (forming acetate from the pro-S carboxymethyl group of citrate)EC 4.1.3.7 - obsolete, reclassified now as citrate (Si)-synthase, EC 2.3.3.1EC 4.1.3.8 - obsolete, reclassified now as ATP citrate synthase, EC 2.3.3.8EC 4.1.3.9 - obsolete, reclassified now as 2-hydroxyglutarate synthase, EC 2.3.3.11EC 4.1.3.10 - obsolete, reclassified now as 3-ethylmalate synthase, EC 2.3.3.7EC 4.1.3.11 - obsolete, reclassified now as 3-propylmalate synthase, EC 2.3.3.12EC 4.1.3.12 - obsolete, reclassified now as 2-isopropylmalate synthase, EC 2.3.3.13EC 4.1.3.13 - 3-oxalomalate glyoxylate-lyase (oxaloacetate-forming)EC 4.1.3.14 - erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase (glycine-forming)EC 4.1.3.15 - obsolete, reclassified now as 2-hydroxy-3-oxoadipate synthase, EC 2.2.1.5EC 4.1.3.16 - 4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming) EC 4.1.3.17 - 4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming) EC 4.1.3.18 - obsolete, reclassified now as acetolactate synthase, EC 2.2.1.6EC 4.1.3.19 - obsolete, reclassified now as N-acetylneuraminate synthase, EC 2.5.1.56EC 4.1.3.20 - obsolete, reclassified now as N-acylneuraminate-9-phosphate synthase, EC 2.5.1.57EC 4.1.3.21 - obsolete, reclassified now as homocitrate synthase, EC 2.3.3.14EC 4.1.3.22 - (2S)-2-hydroxy-2-methylbutanedioate pyruvate-lyase (acetate-forming)EC 4.1.3.23 - obsolete, reclassified now as decylcitrate synthase, EC 2.3.3.2EC 4.1.3.24 - (3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase (acetyl-CoA-forming)EC 4.1.3.25 - (3S)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming)EC 4.1.3.26 - 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase (7-methyl-3-oxooct-6-enoyl-CoA-forming)EC 4.1.3.27 - chorismate pyruvate-lyase (amino-accepting; anthranilate-forming)EC 4.1.3.28 - obsolete, reclassified now as citrate (Re)-synthase, EC 2.3.3.3EC 4.1.3.29 - obsolete, reclassified now as decylhomocitrate synthase, EC 2.3.3.4EC 4.1.3.30 - (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase (succinate-forming)EC 4.1.3.31 - obsolete, reclassified now as 2-methylcitrate synthase, EC 2.3.3.5EC 4.1.3.32 - 2,3-dimethylmalate pyruvate-lyase (propanoate-forming)EC 4.1.3.33 - obsolete, reclassified now as 2-ethylmalate synthase, EC 2.3.3.6EC 4.1.3.34 - (3S)-citryl-CoA oxaloacetate-lyase (acetyl-CoA-forming)EC 4.1.3.35 - (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming)EC 4.1.3.36 - o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing; CoA-forming)EC 4.1.3.37 - obsolete, reclassified now as 3-ethylmalate synthase, EC 2.2.1.7EC 4.1.3.38 - 4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming)EC 4.1.3.39 - 4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming)EC 4.1.3.40 - chorismate pyruvate-lyase (4-hydroxybenzoate-forming) |  |