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EC 1: Oxidoreductases
EC 2: Transferases
EC 3: Hydrolases
EC 4: Lyases
EC 5: Isomerases
EC 6: Ligases
Enzymes in industry
EC 2. Transferase, Nomenclature
Transferase definitionAccording to the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB) classification, EC 2 Transferases are enzymes that catalyse, or speed up, the transfer of a chemical group from one compound (donor) to another compound (acceptor). It is important to remember, that in many cases transferase donor is cofactor, or coenzyme, carrying the group to be transferred. A very basic reaction catalysed by transferase can be described in the following diagram:
A-X + B -> A + B-X
It started off with the A attached to the X with B added in the reaction. Those are the two reactants. However, when the catalyst is added and the reaction proceeds, the X is removed from the A faster than it normally would be without an enzyme and then transferred to the B. This reaction is used to make a name for all this class of enzymes. Transfer - is a first part of the word transferase, and the second part of the word -ase is common part for all enzymes.
Transferases are belongs to the EC 2 category and can classified further according to recommendation of Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB).
EC number classification of Transferases.
For example, let us consider enzyme aspartate carbamoyltransferase, EC 18.104.22.168. This enzyme catalyse following reaction:
carbamoyl phosphate + L-aspartate -> phosphate + N-carbamoyl-L-aspartate
Systematic name: carbamoyl-phosphate:L-aspartate carbamoyltransferase
Common names: aspartate carbamyltransferase
Historic name: ATCase
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