EC 4.6.1.1 - ATP diphosphate- lyase (cyclizing; 3',5'- cyclic- AMP- forming) (adenylate cyclase)

3D structures of EC 4.6.1.1 - adenylate cyclase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1ab8: Rat Type II Adenylyl Cyclase C2 Domain/forskolin Complex
2. 1azs: Complex of Gs-alpha with The Catalytic Domains of Mammalian Adenylyl Cyclase
3. 1cjk: Complex of Gs-alpha with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with Adenosine 5'-(alpha Thio)- Triphosphate (rp), Mg, and Mn
4. 1cjt: Complex of Gs-alpha with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with Beta-l-2',3'-dideoxyatp, Mn, and Mg
5. 1cju: Complex of Gs-alpha with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with Beta-l-2',3'-dideoxyatp and Mg
6. 1cjv: Complex of Gs-alpha with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with Beta-l-2',3'-dideoxyatp, Mg, and Zn
7. 1cs4: Complex of Gs-alpha with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with 2'-deoxy-adenosine 3'- Monophosphate, Pyrophosphate and Mg
8. 1cul: Complex of Gs-alpha with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with 2',5'-dideoxy-adenosine 3'- Triphosphate and Mg
9. 1fx2: Structural Analysis of Adenylate Cyclases from Trypanosoma Brucei in Their Monomeric State
10. 1fx4: Structure Analysis of Adenylate Cyclases from Trypanosoma Brucei in Their Monomeric State
11. 1k8t: Crystal Structure of The Adenylyl Cyclase Domain of Anthrax Edema Factor (ef)
12. 1k90: Crystal Structure of The Adenylyl Cyclase Domain of Anthrax Edema Factor (ef) in Complex with Calmodulin and 3' Deoxy- Atp
13. 1k93: Crystal Structure of The Adenylyl Cyclase Domain of Anthrax Edema Factor (ef) in Complex with Calmodulin
14. 1lvc: Crystal Structure of The Adenylyl Cyclase Domain of Anthrax Edema Factor (ef) in Complex with Calmodulin and 2' Deoxy, 3' Anthraniloyl Atp
15. 3n10: Product Complex of Adenylate Cyclase Class IV
16. 3n0z: Adenylate Cyclase Class IV with Active Site Ligand 3at
17. 3n0y: Adenylate Cyclase Class IV with Active Site Ligand Apc
18. 3maa: Complex of Gs-alpha with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with Adenosine 5-o-(l- Thiophosphate) and Low Ca Concentration
19. 1pk0: Crystal Structure of The Ef3-cam Complexed with Pmeapp
20. 6uzd: Anthrax Toxin Protective Antigen Channels Bound to Edema Factor
21. 6uze: Anthrax Toxin Protective Antigen Channels Bound to Edema Factor
22. 3g82: Complex of Gs-alpha with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with Mant-itp and Mn
23. 1s26: Structure of Anthrax Edema Factor-calmodulin-alpha,beta- Methyleneadenosine 5'-triphosphate Complex Reveals an Alternative Mode of Atp Binding to The Catalytic Site
24. 1sk6: Crystal Structure of The Adenylyl Cyclase Domain of Anthrax Edema Factor (ef) in Complex with Calmodulin, 3',5' Cyclic Amp (camp), and Pyrophosphate
25. 1tl7: Complex of Gs- with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with 2'(3')-o-(n- Methylanthraniloyl)-guanosine 5'-triphosphate and Mn
26. 1u0h: Structural Basis for The Inhibition of Mammalian Adenylyl Cyclase by Mant-gtp
27. 3c16: Complex of Gs-alpha with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with Adenosine-5'-triphosphate and Ca
28. 3c15: Complex of Gs-alpha with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with Pyrophosphate and Mg
29. 3c14: Complex of Gs-alpha with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with Pyrophosphate and Ca
30. 1wc0: Soluble Adenylyl Cyclase Cyac from S. Platensis in Complex with Alpha,beta-methylene-atp
31. 1wc1: Soluble Adenylyl Cyclase Cyac from S. Platensis in Complex with Rp-atpalphas
32. 1wc3: Soluble Adenylyl Cyclase Cyac from S. Platensis in Complex with Alpha,beta-methylene-atp and Strontium
33. 1wc4: Soluble Adenylyl Cyclase Cyac from S. Platensis in Complex with Alpha,beta-methylene-atp and Europium
34. 1wc5: Soluble Adenylyl Cyclase Cyac from S. Platensis in Complex with Alpha,beta-methylene-atp in Presence of Bicarbonate
35. 1wc6: Soluble Adenylyl Cyclase Cyac from S. Platensis in Complex with Rp-atpalphas in Presence of Bicarbonate
36. 1xfu: Crystal Structure of Anthrax Edema Factor (ef) Truncation Mutant, Ef-delta 64 in Complex with Calmodulin
37. 1xfv: Crystal Structure of Anthrax Edema Factor (ef) in Complex with Calmodulin and 3' Deoxy-atp
38. 1xfw: Crystal Structure of Anthrax Edema Factor (ef) in Complex with Calmodulin and 3'5' Cyclic Amp (camp)
39. 1xfx: Crystal Structure of Anthrax Edema Factor (ef) in Complex with Calmodulin in The Presence of 10 Millimolar Exogenously Added Calcium Chloride
40. 1xfy: Crystal Structure of Anthrax Edema Factor (ef) in Complex with Calmodulin
41. 1xfz: Crystal Structure of Anthrax Edema Factor (ef) in Complex with Calmodulin in The Presence of 1 Millimolar Exogenously Added Calcium Chloride
42. 1y0v: Crystal Structure of Anthrax Edema Factor (ef) in Complex with Calmodulin and Pyrophosphate
43. 1y10: Mycobacterial Adenylyl Cyclase Rv1264, Holoenzyme, Inhibited State
44. 1y11: Mycobacterial Adenylyl Cyclase Rv1264, Holoenzyme, Active State
45. 1ybt: Mycobacterium Tuberculosis Adenylyl Cyclase, RV1900C Chd
46. 1ybu: Mycobacterium Tuberculosis Adenylyl Cyclase RV1900C Chd, in Complex with a Substrate Analog.
47. 1yk9: Crystal Structure of a Mutant Form of The Mycobacterial Adenylyl Cyclase RV1625C
48. 1ykd: Crystal Structure of The Tandem Gaf Domains from a Cyanobacterial Adenylyl Cyclase: Novel Modes of Ligand- Binding and Dimerization
49. 1yrt: Crystal Structure Analysis of The Adenylyl Cyclaes Catalytic Domain of Adenylyl Cyclase Toxin of Bordetella Pertussis in Presence of C-terminal Calmodulin
50. 1yru: Crystal Structure Analysis of The Adenylyl Cyclaes Catalytic Domain of Adenylyl Cyclase Toxin of Bordetella Pertussis in Presence of C-terminal Calmodulin and 1mm Calcium Chloride
51. 1zot: Crystal Structure Analysis of The Cyaa/c-cam with Pmeapp
52. 6vra: Anthrax Octamer Prechannel Bound to Full-length Edema Factor
53. 2bw7: A Novel Mechanism for Adenylyl Cyclase Inhibition from The Crystal Structure of Its Complex with Catechol Estrogen
54. 6uzb: Anthrax Toxin Protective Antigen Channels Bound to Edema Factor
55. 2col: Crystal Structure Analysis of Cyaa/c-cam with Pyrophosphate
56. 2ev1: Structure of RV1264N, The Regulatory Domain of The Mycobacterial Adenylyl Cylcase Rv1264, at Ph 6.0
57. 2ev2: Structure of RV1264N, The Regulatory Domain of The Mycobacterial Adenylyl Cylcase Rv1264, at Ph 8.5
58. 2ev3: Structure of RV1264N, The Regulatory Domain of The Mycobacterial Adenylyl Cylcase Rv1264, at Ph 5.3
59. 2ev4: Structure of RV1264N, The Regulatory Domain of The Mycobacterial Adenylyl Cylcase Rv1264, with a Salt Precipitant
60. 2fjt: Adenylyl Cyclase Class IV from Yersinia Pestis
61. 2gvd: Complex of Gs- with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with Tnp-atp and Mn
62. 2gvz: Crystal Structure of Complex of Gs- with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with Mant- Atp and Mn
63. 6sus: Crystal Structure of Rtx Domain Blocks IV and V of Adenylate Cyclase Toxin from Bordetella Pertussis
64. 6rfm: Bordetella Pertussis Adenylate Cyclase Toxin Transmembrane Segment 411-490 in Dpc Micelles
65. 4clf: Crystal Structure of Human Soluble Adenylyl Cyclase (apo Form)
66. 4clk: Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with Alpha,beta-methyleneadenosine-5'-triphosphate
67. 4cll: Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with Bicarbonate
68. 4clp: Crystal Structure of Human Soluble Adenylyl Cyclase Complex with Adenosine-3',5'-cyclic-monophosphate
69. 4cls: Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate
70. 4clt: Crystal Structure of Human Soluble Adenylyl Cyclase with Adenosine-3',5'-cyclic-monophosphate and Pyrophosphate
71. 4clu: Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate
72. 4clw: Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with Alpha,beta-methyleneadenosine-5'-triphosphate Soaked with Bisulfite
73. 4cly: Crystal Structure of Human Soluble Adenylyl Cyclase Soaked with Biselenite
74. 4clz: Crystal Structure of Human Soluble Adenylyl Cyclase with Inhibitor 4,4'-diisothiocyano-2,2'-stilbenedisulfonic Acid
75. 4cm0: Crystal Structure of Human Soluble Adenylyl Cyclase with Alpha,beta-methyleneadenosine-5'-triphosphate Soaked with Bicarbonate
76. 4cm2: Crystal Structure of Human Soluble Adenylyl Cyclase Soaked with Bisulfite
77. 4oya: Human Solac Complexed with (4-aminofurazan-3-yl)-[3-(1h-benzoimidazol- 2-ylmethoxy)phenyl]methanone
78. 4oyb: Crystal Structure Analysis of The Solac
79. 4oyi: Human Solac Complexed with (4-amino-furazan-3-yl)-phenyl-methanone
80. 4oym: Human Solac Complexed with (4-amino-furazan-3-yl)-(3-methoxy-phenyl)- Methanone
81. 4oyo: Human Solac Complexed with 4-(2-chlorophenyl)-3-methyl-1h-pyrazole
82. 4oyp: Human Solac Complexed with 1-benzofuran-2-carboxylic Acid
83. 4oyw: Crystal Structure of Human Soluble Adenylate Cyclase
84. 4oyx: Human Solac Complexed with Ampcpp
85. 4oyz: Human Solac Complexed with Bicarbonate
86. 4oz2: Human Solac Complexed with 4-(4-fluorophenyl)-3-methyl-1h-pyrazole
87. 4oz3: Human Solac Complexed with 4-phenyl-3-(trifluoromethyl)-1h-pyrazole
88. 4p2f: Monomeric Form of a Single Mutant (F363R) of Mycobacterial Adenylyl Cyclase RV1625C
89. 4p2m: Swapped Dimer of Mycobacterial Adenylyl Cyclase RV1625C: Form 1
90. 4p2x: Swapped Dimer of Mycobacterial Adenylyl Cyclase RV1625C: Form 2
91. 4ust: Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate Resulting from Soaking with Gtp and Magnesium
92. 4usu: Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with Alpha,beta-methyleneadenosine-5'-triphosphate
93. 4usv: Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate Resulting from Soaking with Atp and Calcium
94. 4usw: Crystal Structure of Human Soluble Adenylyl Cyclase with Atp
95. 5o5l: X-ray Structure of a Bacterial Adenylyl Cyclase Soluble Domain, Solved at Cryogenic Temperature
96. 5o5k: X-ray Structure of a Bacterial Adenylyl Cyclase Soluble Domain
97. 5iv4: Crystal Structure of The Human Soluble Cyclase in Complex with The Allosteric Inhibitor Lre1
98. 5iv3: Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with Alpha,beta-methyleneadenosine-5'-triphosphate and The Allosteric Inhibitor Lre1
99. 5d0r: Crystal Structure of Human Soluble Adenylyl Cyclase with The Inhibitor Bithionol
100. 5cxl: Crystal Structure of Rtx Domain Block V of Adenylate Cyclase Toxin from Bordetella Pertussis
101. 5cvw: Crystal Structure of Rtx Domain Block V of Adenylate Cyclase Toxin from Bordetella Pertussis
102. 4yut: Crystal Structure of Photoactivated Adenylyl Cyclase of a Cyanobacteriaoscillatoria Acuminata in Orthorhombic Form
103. 4yus: Crystal Structure of Photoactivated Adenylyl Cyclase of a Cyanobacteriaoscillatoria Acuminata in Hexagonal Form
104. 4wp3: Crystal Structure of Adenylyl Cyclase from Mycobacterium Avium Ma1120 Wild Type
105. 4wp8: Crystal Structure of Adenylyl Cyclase Ma1120 from Mycobacterium Avium in Complex with 2'5'-dd-3'-atp and Manganese Ion
106. 4wp9: Crystal Structure of Adenylyl Cyclase Ma1120 from Mycobacterium Avium Bound to 2'5'-dd-3'-atp, Calcium and Magnesium Ion
107. 4wpa: Crystal Structure of Adenylyl Cyclase Ma1120 from Mycobacterium Avium Bound to Pyrophosphate and Calcium
108. 7ovd: Human Soluble Adenylyl Cyclase in Complex with The Inhibitor Tdi10229