EC 2.3.1.41 - acyl- [acyl- carrier protein] :malonyl- [acyl- carrier protein] C- acyltransferase (decarboxylating) (\xCE\xB2- ketoacyl- acyl- carrier- protein synthase I)

3D structures of EC 2.3.1.41 - \xCE\xB2-ketoacyl-acyl-carrier-protein synthase I in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1b3n: Beta-ketoacyl Carrier Protein Synthase as a Drug Target, Implications from The Crystal Structure of a Complex with The Inhibitor Cerulenin.
2. 1dd8: Crystal Structure of Beta-ketoacyl-[acyl Carrier Protein] Synthase I from Escherichia Coli
3. 1e5m: Beta Ketoacyl Acyl Carrier Protein Synthase II (kasii) from Synechocystis Sp.
4. 1ebl: The 1.8 a Crystal Structure and Active Site Architecture of Beta-ketoacyl-[acyl Carrier Protein] Synthase III (fabh) from Escherichia Coli
5. 1ek4: Beta-ketoacyl [acyl Carrier Protein] Synthase I in Complex with Dodecanoic Acid to 1.85 Resolution
6. 1f91: Beta-ketoacyl-[acyl-carrier-protein] Synthase I in Complex with C10 Fatty Acid Substrate
7. 1fj4: The Structure of Beta-ketoacyl-[acyl Carrier Protein] Synthase I in Complex with Thiolactomycin, Implications for Drug Design
8. 1fj8: The Structure of Beta-ketoacyl-[acyl Carrier Protein] Synthase I in Complex with Cerulenin, Implications for Drug Design
9. 1g5x: The Structure of Beta-ketoacyl-[acyl Carrier Protein] Synthase I
10. 1h4f: E. Coli Beta-ketoacyl [acyl Carrier Protein] Synthase I K328R
11. 1hn9: Crystal Structure of Beta-ketoacyl-acp Synthase III
12. 1hnd: Crystal Structure of Beta-ketoacyl-acp Synthase Iii-coa Complex
13. 1hnh: Crystal Structure of Beta-ketoacyl-acp Synthase III + Degraded Form of Acetyl-coa
14. 1hnj: Crystal Structure of Beta-ketoacyl-acp Synthase III + Malonyl-coa
15. 1hnk: Crystal Structure of Beta-ketoacyl-acp Synthase Iii, Apo Tetragonal Form
16. 1hzp: Crystal Structure of The Myobacterium Tuberculosis Beta- Ketoacyl-acyl Carrier Protein Synthase III
17. 1j3n: Crystal Structure of 3-oxoacyl-(acyl-carrier Protein) Synthase II from Thermus Thermophilus Hb8
18. 1kas: Beta-ketoacyl-acp Synthase II from Escherichia Coli
19. 1m1m: X-ray Crystal Structure of Mycobacterium Tuberculosis Beta- Ketoacyl-acyl Carrier Protein Synthase III (mtfabh)
20. 1mzj: Crystal Structure of The Priming Beta-ketosynthase from The R1128 Polyketide Biosynthetic Pathway
21. 1mzs: Crystal Structure of Beta-ketoacyl-acp Synthase III with Bound Dichlorobenzyloxy-indole-carboxylic Acid Inhibitor
22. 3lrf: Crystal Structure of Beta-ketoacyl Synthase from Brucella Melitensis
23. 3led: Crystal Structure of 3-oxoacyl-(acyl Carrier Protein) Synthase III from Rhodopseudomonas Palustris Cga009
24. 3kzu: Crystal Structure of 3-oxoacyl-(acyl Carrier Protein) Synthase II from Brucella Melitensis
25. 1ox0: The Crystal Structure of Beta-ketoacyl-[acyl Carrier Protein] Synthase II from Streptococcus Pneumoniae
26. 1oxh: The Crystal Structure of Beta-ketoacyl-[acyl Carrier Protein] Synthase II from Streptococcus Pneumoniae, Triclinic Form
27. 3fk5: Crystal Structure of 3-oxoacyl-(acyl Carrier Protein) Synthase Iii, Fabh (xoo4209) from Xanthomonas Oryzae Pv. Oryzae Kacc10331
28. 1u6e: 1.85 Angstrom Crystal Structure of The C112A Mutant of Mycobacterium Tuberculosis Beta-ketoacyl-acyl Carrier Protein Synthase III (fabh)
29. 1u6s: Crystal Structure of The Complex between Mycobacterium Tuberculosis Beta-ketoacyl-acyl Carrier Protein Synthase III and Lauroyl Coenzyme a
30. 1ub7: The Crystal Analysis of Beta-keroacyl-[acyl Carrier Protein] Synthase III (fabh)from Thermus Thermophilus.
31. 1w0i: Arabidopsis Thaliana Mitochondrial Kas
32. 2wgg: Crystal Structure of Mycobacterium Tuberculosis C171Q Kasa Variant with Bound Tlm
33. 2wgf: Crystal Structure of Mycobacterium Tuberculosis C171Q Kasa Variant
34. 2wge: Crystal Structure of Kasa of Mycobacterium Tuberculosis with Bound Tlm
35. 2wgd: Crystal Structure of Kasa of Mycobacterium Tuberculosis
36. 2wat: Structure of The Fungal Type I Fas Ppt Domain in Complex with Coa
37. 2was: Structure of The Fungal Type I Fas Ppt Domain
38. 1zow: Crystal Structure of S. Aureus Fabh, Beta-ketoacyl Carrier Protein Synthase III
39. 2vkz: Structure of The Cerulenin-inhibited Fungal Fatty Acid Synthase Type I Multienzyme Complex
40. 2vba: Beta-ketoacyl-acp Synthase I (kas) from E. Coli with Bound Amino-thiazole Inhibitor
41. 2vb9: Beta-ketoacyl-acp Synthase I (kas) from E. Coli, Apo Structure
42. 2vb8: Beta-ketoacyl-acp Synthase I (kas) from E. Coli with Bound Inhibitor Thiolactomycin
43. 2vb7: Beta-ketoacyl-acp Synthase I (kas) from E. Coli, Apo Structure after Soak in Peg Solution
44. 2ahb: X-ray Crystal Structure of R46A,R161A Mutant of Mycobacterium Tuberculosis Fabh
45. 2aj9: X-ray Crystal Structure of W42A,R161A Double Mutant of Mycobacterium Tuberculosis Beta-ketoacyl-acp Synthase III
46. 2alm: Crystal Structure Analysis of a Mutant Beta-ketoacyl-[acyl Carrier Protein] Synthase II from Streptococcus Pneumoniae
47. 2aq7: Structure-activity Relationships at The 5-posiiton of Thiolactomycin: an Intact 5(r)-isoprene Unit Is Required for Activity against The Condensing Enzymes from Mycobacterium Tuberculosis and Escherichia Coli
48. 2aqb: Structure-activity Relationships at The 5-position of Thiolactomycin: an Intact 5(r)-isoprene Unit Is Required for Activity against The Condensing Enzymes from Mycobacterium Tuberculosis and Escherchia Coli
49. 2rjt: Crystal Structure Analysis of a Surface Entropy Reduction Mutant of S. Pneumoniae Fabf
50. 2buh: E. Coli Beta-ketoacyl (acyl Carrier Protein) Synthase I, 120 K
51. 2bui: E.coli Beta-ketoacyl (acyl Carrier Protein) Synthase I in Complex with Octanoic Acid, 120k
52. 2byw: Structure of Escherichia Coli Beta-ketoacyl (acyl Carrier Protein) Synthase I LYS328ALA Mutant
53. 2byx: Kas I LYS328ALA Mutant in Complex with Fatty Acid
54. 2byy: E. Coli Kas I H298E Mutation
55. 2byz: Structure of E. Coli Kas I H298Q Mutant in Complex with C12 Fatty Acid
56. 2bz3: Structure of E. Coli Kas I H298E Mutant in Complex with C12 Fatty Acid
57. 2bz4: Structure of E. Coli Kas I H298Q Mutant
58. 2qx1: Crystal Structure of The Complex between Mycobacterium Tuberculosis Beta-ketoacyl-acyl Carrier Protein Synthase III (fabh) and Decyl-coa Disulfide
59. 2qo1: 2.6 Angstrom Crystal Structure of The Complex between 11- (decyldithiocarbonyloxy)-undecanoic Acid and Mycobacterium Tuberculosis Fabh.
60. 2qo0: Crystal Structure of The Complex between The A246F Mutant of Mycobacterium Beta-ketoacyl-acyl Carrier Protein Synthase III (fabh) and 11-(decyldithiocarbonyloxy)- Undecanoic Acid
61. 2qnz: Crystal Structure of The Complex between The Mycobacterium Beta-ketoacyl-acyl Carrier Protein Synthase III (fabh) and Ss-(2-hydroxyethyl)-o-decyl Ester Carbono(dithioperoxoic) Acid
62. 2qny: Crystal Structure of The Complex between The A246F Mutant of Mycobacterium Beta-ketoacyl-acyl Carrier Protein Synthase III (fabh) and Ss-(2-hydroxyethyl) O-decyl Ester Carbono(dithioperoxoic) Acid
63. 2qnx: Crystal Structure of The Complex between The Mycobacterium Beta-ketoacyl-acyl Carrier Protein Synthase III (fabh) and 11-[(decyloxycarbonyl)dithio]-undecanoic Acid
64. 2c9h: Structure of Mitochondrial Beta-ketoacyl Synthase
65. 6b2t: Crystal Structure of Xanthomonas Campestris Olea H285D
66. 6b2s: Crystal Structure of Xanthomonas Campestris Olea H285N
67. 6b2r: Crystal Structure of Xanthomonas Campestris Olea H285A
68. 2ebd: Crystal Structure of 3-oxoacyl-[acyl-carrier-protein] Synthase III from Aquifex Aeolicus Vf5
69. 2eft: Methanethiol-cys 112 Inhibition Complex of E. Coli Ketoacyl Synthase III (fabh) and Coenzyme a (high Concentration (1.7mm) Soak)
70. 2gfv: Structure of E. Coli Fabf (kasii) C163Q Mutant
71. 2gfw: Structure of Wild Type E. Coli Fabf (kasii)
72. 2gfx: Structure of E. Coli FABF(C163Q) in Complex with Platensimycin
73. 2gfy: Structure of E. Coli FABF(K335A) Mutant with Covalently Linked Dodecanoic Acid
74. 2gp6: X-ray Crystal Structure of Mycobacterium Tuberculosis Beta- Ketoacyl Acyl Carrier Protein Synthase II (mtkasb)
75. 2gqd: The Crystal Structure of B-ketoacyl-acp Synthase II (fabf) from Staphylococcus Aureus
76. 5yzu: Crystal Structure of Kas III from Acinetobacter Baumannii
77. 2gyo: Methanethiol-cys 112 Inhibition Complex of E. Coli Ketoacyl Synthase III (fabh) and Coenzyme a
78. 5yoa: Crystal Structure of Kas III from Acinetobacter Baumannii
79. 5yo9: Crystal Structure of Kas III from Acinetobacter Baumannii
80. 2iwy: Human Mitochondrial Beta-ketoacyl Acp Synthase
81. 2iwz: Human Mitochondrial Beta-ketoacyl Acp Synthase Complexed with Hexanoic Acid
82. 2ix4: Arabidopsis Thaliana Mitochondrial Beta-ketoacyl Acp Synthase Hexanoic Acid Complex
83. 6kue: The Structure of Bioz from Agrobacterium Tumefaciens
84. 6wc7: Acyl Carrier Protein (acp) Domain Bound to Dehydratase (dh) Domain in Fungal Fatty Acid Synthase (fas)
85. 6okf: Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, Fabb, and C16-crypto Acyl Carrier Protein, Acpp
86. 6rcx: Mycobacterial 4'-phosphopantetheinyl Transferase Pptab in Complex with The Acp Domain of Ppsc.
87. 6okc: Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, Fabb, and C12-crypto Acyl Carrier Protein, Acpp
88. 6p9m: Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with O6J
89. 6p9l: Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with Jfx
90. 6p9k: Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with O6G
91. 6u5w: Electron Cryomicroscopy Structure of C. Albicans Fas in The Ks-stalled State
92. 6u5v: Electron Cryomicroscopy Structure of C. Albicans Fas in The Apo State
93. 6u5u: Electron Cryomicroscopy Structure of S. Cerevisiae Fas in The Ks- Stalled State
94. 6u5t: Electron Cryomicroscopy Structure of S. Cerevisiae Fas in The Apo State
95. 3tjm: Crystal Structure of The Human Fatty Acid Synthase Thioesterase Domain with an Activate Site-specific Polyunsaturated Fatty Acyl Adduct
96. 3u0f: The Structure of Beta-ketoacyl Synthase from Brucella Melitensis Bound to The Fragment 7-hydroxycoumarin
97. 3u0e: Crystal Structure of Beta-ketoacyl Synthase from Brucella Melitensis in Complex with Fragment 9320
98. 6rop: Ks-mat Di-domain of Mouse Fas with Octanoyl Coa
99. 6qsp: Ketosynthase (apeo) in Complex with Its Chain Length Factor (apec) from Xenorhabdus Doucetiae
100. 4efi: Crystal Structure of 3-oxoacyl-(acyl-carrier Protein) Synthase from Burkholderia Xenovorans Lb400
101. 3row: Crystal Structure of Xanthomonas Campestri Olea
102. 6nna: Human Fatty Acid Synthase Psi/kr Tri-domain with Nadph and Compound 22
103. 4jv3: Crystal Structure of Beta-ketoacyl Synthase from Brucella Melitensis in Complex with Platencin
104. 4c6u: Crystal Structure of M. Tuberculosis Kasa in Complex with Tlm5
105. 4c6v: Crystal Structure of M. Tuberculosis Kasa in Complex with Tlm5 (soak for 5 Min)
106. 4c6w: Crystal Structure of M. Tuberculosis C171Q Kasa
107. 4c6x: Crystal Structure of M. Tuberculosis C171Q Kasa in Complex with Thiolactomycin (tlm)
108. 4c6z: Crystal Structure of M. Tuberculosis C171Q Kasa in Complex with Tlm3
109. 4c70: Crystal Structure of M. Tuberculosis C171Q Kasa in Complex with Tlm4
110. 4c71: Crystal Structure of M. Tuberculosis C171Q Kasa in Complex with Tlm18
111. 4c72: Crystal Structure of M. Tuberculosis C171Q Kasa in Complex with Tlm5
112. 4c73: Crystal Structure of M. Tuberculosis C171Q Kasa in Complex with Tlm6
113. 4mz0: Structure of a Ketosynthase-acyltransferase Di-domain from Module Curl of The Curacin a Polyketide Synthase
114. 5w2s: Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with Kmg
115. 5w2q: Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with 6u5
116. 5w2p: Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with 6u5
117. 5w2o: Crystal Structure of Mycobacterium Tuberculosis Kasa
118. 5vxh: Crystal Structure of Xanthomonas Campestris Olea E117D
119. 5vxf: Crystal Structure of Xanthomonas Campestris Olea E117Q
120. 5vxd: Crystal Structure of Xanthomonas Campestris Olea E117A
121. 5nji: Structure of The Dehydratase Domain of Ppsc from Mycobacterium Tuberculosis in Complex with C12:1-coa
122. 5my2: Ks-mat Di-domain of Mouse Fas
123. 5my0: Ks-mat Di-domain of Mouse Fas with Malonyl-coa
124. 5ld8: GSK3011724A Cocrystallised with Mycobacterium Tuberculosis H37RV Kasa
125. 5l84: Structure of The H959F Variant of The Ppsc Dehydratase Domain from Mycobacterium Tuberculosis
126. 5kof: Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, Fabb, and Acyl Carrier Protein, Acpp
127. 5i0k: Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases
128. 6fn6: Modifying Region (dh-er-kr) of an Insect Fatty Acid Synthase (fas)
129. 5c37: Structure of The Beta-ketoacyl Reductase Domain of Human Fatty Acid Synthase Bound to a Spiro-imidazolone Inhibitor
130. 4xox: Structure of Beta-ketoacyl-acp Synthase I (fabb) from Vibrio Cholerae
131. 4oki: X-ray Structure of The Nucleotide-binding Subdomain of The Enoylreductase Domain of Ppsc from Mycobacterium Tuberculosis
132. 4ooc: Dehydratase Domain of The Polyketide Ppsc from Mycobacterium Tuberculosis
133. 7bc4: Cryo-em Structure of Fatty Acid Synthase (fas) from Pichia Pastoris
134. 7bc5: Cryo-em Structure of Acp Domain from Pichia Pastoris Fatty Acid Synthase (fas)
135. 7pps: Apo Fabb from Pseudomonas Aeruginosa with Single Point Mutation C161A