EC 2.7.10.1 - ATP:[protein] - L- tyrosine O- phosphotransferase (receptor- type) (receptor protein- tyrosine kinase)

3D structures of EC 2.7.10.1 - receptor protein-tyrosine kinase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1flt: Vegf in Complex with Domain 2 of The Flt-1 Receptor
2. 1igr: Type 1 Insulin-like Growth Factor Receptor (domains 1-3)
3. 3pls: Ron in Complex with Ligand Amp-pnp
4. 6i82: Crystal Structure of Partially Phosphorylated Ret V804M Tyrosine Kinase Domain Complexed with Pdd00018412
5. 6i83: Crystal Structure of Phosphorylated Ret V804M Tyrosine Kinase Domain Complexed with Pdd00018366
6. 3nw7: Crystal Structure of Insulin-like Growth Factor 1 Receptor (igf-1r-wt) Complex with a Carbon-linked Proline Isostere Inhibitor (34)
7. 3nw6: Crystal Structure of Insulin-like Growth Factor 1 Receptor (igf-1r-wt) Complex with a Carbon-linked Proline Isostere Inhibitor (11a)
8. 3nw5: Crystal Structure of Insulin-like Growth Factor 1 Receptor (igf-1r-wt) Complex with a Carbon-linked Proline Isostere Inhibitor (11b)
9. 3njp: The Extracellular and Transmembrane Domain Interfaces in Epidermal Growth Factor Receptor Signaling
10. 1m6b: Structure of The Her3 (erbb3) Extracellular Domain
11. 3n85: Crystallographic Trimer of Her2 Extracellular Regions in Complex with Tryptophan-rich Antibody Fragment
12. 3mzw: Her2 Extracelluar Region with Affinity Matured 3-helix Affibody Zher2:342
13. 3mx0: Crystal Structure of Epha2 Ectodomain in Complex with Ephrin-a5
14. 6q7b: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with The Nvp-bhg712 Derivative Atdl09
15. 6q7c: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with The Nvp-bhg712 Derivative Atdl11
16. 3mjg: The Structure of a Platelet Derived Growth Factor Receptor Complex
17. 1mw4: Solution Structure of The Human Grb7-sh2 Domain in Complex with a 10 Amino Acid Peptide Py1139
18. 3mbw: Crystal Structure of The Human Ephrin A2 Lbd and Crd Domains in Complex with Ephrin A1
19. 6jk8: Cryo-em Structure of The Full-length Human Igf-1r in Complex with Insulin
20. 3lw0: Igf-1rk in Complex with Ligand MSC1609119A-1
21. 3lvp: Crystal Structure of Bisphosphorylated Igf1-r Kinase Domain (2p) in Complex with a Bis-azaindole Inhibitor
22. 3lq8: Structure of The Kinase Domain of C-met Bound to Xl880 (gsk1363089)
23. 3lmg: Crystal Structure of The Erbb3 Kinase Domain in Complex with Amp-pnp
24. 3lct: Crystal Structure of The Anaplastic Lymphoma Kinase Catalytic Domain
25. 3lcs: Crystal Structure of The Anaplastic Lymphoma Kinase Catalytic Domain
26. 3lco: Inhibitor Bound to a Dfg-out Structure of The Kinase Domain of Csf-1r
27. 3lcd: Inhibitor Bound to a Dfg-in Structure of The Kinase Domain of Csf-1r
28. 3l9p: Crystal Structure of The Anaplastic Lymphoma Kinase Catalytic Domain
29. 3l8v: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with a Biarylamine Based Inhibitor
30. 3l8p: Crystal Structure of Cytoplasmic Kinase Domain of Tie2 Complexed with Inhibitor Cep11207
31. 3ky2: Crystal Structure of Fibroblast Growth Factor Receptor 1 Kinase Domain
32. 3kxx: Structure of The Mutant Fibroblast Growth Factor Receptor 1
33. 3kvq: Crystal Structure of Vegfr2 Extracellular Domain D7
34. 3kul: Kinase Domain of Human Ephrin Type-a Receptor 8 (epha8)
35. 3krl: Cfms Tyrosine Kinase in Complex with 5-cyano-furan-2-carboxylic Acid [4-(4-methyl-piperazin-1-yl)-2-piperidin-1-yl-phenyl]-amide
36. 3krj: Cfms Tyrosine Kinase in Complex with 4-cyano-1h-imidazole-2-carboxylic Acid (2-cyclohex-1-enyl-4-piperidin-4-yl-phenyl)-amide
37. 3kka: Co-crystal Structure of The Sam Domains of Epha1 and Epha2
38. 3kex: Crystal Structure of The Catalytically Inactive Kinase Domain of The Human Epidermal Growth Factor Receptor 3 (her3)
39. 3js2: Crystal Structure of Minimal Kinase Domain of Fibroblast Growth Factor Receptor 1 in Complex with 5-(2-thienyl) Nicotinic Acid
40. 3ika: Crystal Structure of Egfr 696-1022 T790M Mutant Covalently Binding to Wz4002
41. 3i5n: Crystal Structure of C-met with Triazolopyridazine Inhibitor 13
42. 3hpn: Ligand Recognition by A-class Eph Receptors: Crystal Structures of The Epha2 Ligand-binding Domain and The Epha2/ephrin-a1 Complex
43. 3hng: Crystal Structure of Vegfr1 in Complex with N-(4- Chlorophenyl)-2-((pyridin-4-ylmethyl)amino)benzamide
44. 3hkl: Crystal Structure of The Frizzled-like Cysteine-rich Domain of Musk
45. 3hil: Sam Domain of Human Ephrin Type-a Receptor 1 (epha1)
46. 3hei: Ligand Recognition by A-class Eph Receptors: Crystal Structures of The Epha2 Ligand-binding Domain and The Epha2/ephrin-a1 Complex
47. 3h8m: Sam Domain of Human Ephrin Type-a Receptor 7 (epha7)
48. 3h3b: Crystal Structure of The Single-chain Fv (scfv) Fragment of an Anti- Erbb2 Antibody Cha21 in Complex with Residues 1-192 of Erbb2 Extracellular Domain
49. 3gxu: Crystal Structure of Eph Receptor and Ephrin Complex
50. 3gt8: Crystal Structure of The Inactive Egfr Kinase Domain in Complex with Amp-pnp
51. 3gql: Crystal Structure of Activated Receptor Tyrosine Kinase in Complex with Substrates
52. 3gqi: Crystal Structure of Activated Receptor Tyrosine Kinase in Complex with Substrates
53. 3gop: Crystal Structure of The Egf Receptor Juxtamembrane and Kinase Domains
54. 3g0f: Kit Kinase Domain Mutant D816H in Complex with Sunitinib
55. 3g0e: Kit Kinase Domain in Complex with Sunitinib
56. 3fy2: Human Epha3 Kinase and Juxtamembrane Region Bound to Substrate Kqwdnyefiw
57. 3fxx: Human Epha3 Kinase and Juxtamembrane Region Bound to Substrate Kqwdnye[ptyr]iw
58. 3fl7: Crystal Structure of The Human Ephrin A2 Ectodomain
59. 3f82: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with N- (4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4- Ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3- Carboxamide
60. 3f66: Human C-met Kinase in Complex with Quinoxaline Inhibitor
61. 3f5p: Complex Structure of Insulin-like Growth Factor Receptor and 3-cyanoquinoline Inhibitor
62. 6ubw: Met Tyrosine Kinase Inhibition Enhances The Antitumor Efficacy of an Hgf Antibody
63. 3ewh: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Pyridyl-pyrimidine Benzimidazole Inhibitor
64. 3euu: Crystal Structure of The Fgfr2 D2 Domain
65. 3etp: The Crystal Structure of The Ligand-binding Domain of The Ephb2 Receptor at 2.0 a Resolution
66. 3eta: Kinase Domain of Insulin Receptor Complexed with a Pyrrolo Pyridine Inhibitor
67. 3ekn: Insulin Receptor Kinase Complexed with an Inhibitor
68. 3ekk: Insulin Receptor Kinase Complexed with an Inhibitor
69. 3ejj: Structure of M-csf Bound to The First Three Domains of Fms
70. 3efl: Crystal Structure of The Vegfr2 Kinase Domain in Complex with Motesanib
71. 3efk: Structure of C-met with Pyrimidone Inhibitor 50
72. 3efj: Structure of C-met with Pyrimidone Inhibitor 7
73. 3dzq: Human Epha3 Kinase Domain in Complex with Inhibitor Awl-ii- 38.3
74. 3dtw: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Benzisoxazole Inhibitor
75. 3dpk: Cfms Tyrosine Kinase in Complex with a Pyridopyrimidinone Inhibitor
76. 3dko: Complex between The Kinase Domain of Human Ephrin Type-a Receptor 7 (epha7) and Inhibitor Alw-ii-49-7
77. 3dar: Crystal Structure of D2 Domain from Human Fgfr2
78. 3d94: Crystal Structure of The Insulin-like Growth Factor-1 Receptor Kinase in Complex with Pqip
79. 3czu: Crystal Structure of The Human Ephrin A2- Ephrin A1 Complex
80. 3cu1: Crystal Structure of 2:2:2 FGFR2D2:FGF1:SOS Complex
81. 3ctj: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with a Aminopyridine Based Inhibitor
82. 3cth: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with a Aminopyridine Based Inhibitor
83. 3cpc: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Pyridone Inhibitor
84. 3cpb: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Bisamide Inhibitor
85. 3cp9: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Pyridone Inhibitor
86. 3cly: Crystal Structure of Fgf Receptor 2 (fgfr2) Kinase Domains Trapped in Trans-phosphorylation Reaction
87. 3ckh: Crystal Structure of Eph A4 Receptor
88. 3cjg: Crystal Structure of Vegfr2 in Complex with a 3,4,5- Trimethoxy Aniline Containing Pyrimidine
89. 3cjf: Crystal Structure of Vegfr2 in Complex with a 3,4,5- Trimethoxy Aniline Containing Pyrimidine
90. 3ce3: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with a Pyrrolopyridinepyridone Based Inhibitor
91. 3cd8: X-ray Structure of C-met with Triazolopyridazine Inhibitor.
92. 3ccn: X-ray Structure of C-met with Triazolopyridazine Inhibitor.
93. 3caf: Crystal Structure of Hfgfr2 D2 Domain
94. 3c8x: Crystal Structure of The Ligand Binding Domain of Human Ephrin A2 (epha2) Receptor Protein Kinase
95. 3c7q: Structure of Vegfr2 Kinase Domain in Complex with Bibf1120
96. 3c4f: Fgfr Tyrosine Kinase Domain in Complex with 3-(3- Methoxybenzyl)-7-azaindole
97. 3c1x: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with a Pyrrolotriazine Based Inhibitor
98. 3c09: Crystal Structure The Fab Fragment of Matuzumab (fab72000) in Complex with Domain III of The Extracellular Region of Egfr
99. 3bu6: Crystal Structure of The Insulin Receptor Kinase in Complex with Irs2 Krlb Phosphopeptide
100. 3bu5: Crystal Structure of The Insulin Receptor Kinase in Complex with Irs2 Krlb Peptide and Atp
101. 3bu3: Crystal Structure of The Insulin Receptor Kinase in Complex with Irs2 Krlb Peptide
102. 3brb: Crystal Structure of Catalytic Domain of The Proto-oncogene Tyrosine- Protein Kinase Mer in Complex with Adp
103. 3bpr: Crystal Structure of Catalytic Domain of The Proto-oncogene Tyrosine- Protein Kinase Mer in Complex with Inhibitor C52
104. 3bel: X-ray Structure of Egfr in Complex with Oxime Inhibitor
105. 3bea: Cfms Tyrosine Kinase (tie2 Kid) in Complex with a Pyrimidinopyridone Inhibitor
106. 3be2: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Benzamide Inhibitor
107. 3be1: Dual Specific Bh1 Fab in Complex with The Extracellular Domain of Her2/erbb-2
108. 3bce: Crystal Structure of The Erbb4 Kinase
109. 3bbw: Crystal Structure of The Erbb4 Kinase in Its Inactive Conformation
110. 3bbt: Crystal Structure of The Erbb4 Kinase in Complex with Lapatinib
111. 3b8r: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Naphthamide Inhibitor
112. 3b8q: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Naphthamide Inhibitor
113. 3b2v: Crystal Structure of The Extracellular Region of The Epidermal Growth Factor Receptor in Complex with The Fab Fragment of Imc-11f8
114. 3b2u: Crystal Structure of Isolated Domain III of The Extracellular Region of The Epidermal Growth Factor Receptor in Complex with The Fab Fragment of Imc-11f8
115. 3b2t: Structure of Phosphotransferase
116. 3a4p: Human C-met Kinase Domain Complexed with 6- Benzyloxyquinoline Inhibitor
117. 2zm3: Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor
118. 2z8c: Phosphorylated Insulin Receptor Tyrosine Kinase in Complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2- Yl]amino}phenyl)acetic Acid
119. 2z4f: Solution Structure of The Discoidin Domain of Ddr2
120. 2ys5: Solution Structure of The Complex of The Ptb Domain of Snt-2 and 19- Residue Peptide (aa 1571-1589) of Halk
121. 2xp2: Structure of The Human Anaplastic Lymphoma Kinase in Complex with Crizotinib (pf-02341066)
122. 2xba: Structure of Human Anaplastic Lymphoma Kinase in Complex with Pha-e429
123. 2xb7: Structure of Human Anaplastic Lymphoma Kinase in Complex with Nvp- Tae684
124. 2xac: Structural Insights into The Binding of Vegf-b by Vegfr-1d2: Recognition and Specificity
125. 2x9f: Ephb4 Kinase Domain Inhibitor Complex
126. 2x2u: First Two Cadherin-like Domains from Human Ret
127. 2x2m: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain with Inhibitor
128. 2x2l: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain with Inhibitor
129. 2x2k: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain with Inhibitor
130. 2x11: Crystal Structure of The Complete Epha2 Ectodomain in Complex with Ephrin A5 Receptor Binding Domain
131. 2x10: Crystal Structure of The Complete Epha2 Ectodomain
132. 2wqb: Structure of The Tie2 Kinase Domain in Complex with a Thiazolopyrimidine Inhibitor
133. 2wo3: Crystal Structure of The Epha4-ephrina2 Complex
134. 2wo2: Crystal Structure of The Epha4-ephrinb2 Complex
135. 2wo1: Crystal Structure of The Epha4 Ligand Binding Domain
136. 2wkm: X-ray Structure of Pha-00665752 Bound to The Kinase Domain of C-met
137. 2wgj: X-ray Structure of Pf-02341066 Bound to The Kinase Domain of C-met
138. 1yy9: Structure of The Extracellular Domain of The Epidermal Growth Factor Receptor in Complex with The Fab Fragment of Cetuximab/erbitux/imc-c225
139. 6q7g: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with The Nvp-bhg712 Derivative Atha01
140. 2wd1: Human C-met Kinase in Complex with Azaindole Inhibitor
141. 2vx1: Ephb4 Kinase Domain Inhibitor Complex
142. 2vx0: Ephb4 Kinase Domain Inhibitor Complex
143. 2vwz: Ephb4 Kinase Domain Inhibitor Complex
144. 2vwy: Ephb4 Kinase Domain Inhibitor Complex
145. 2vwx: Ephb4 Kinase Domain Inhibitor Complex
146. 2vww: Ephb4 Kinase Domain Inhibitor Complex
147. 2vwv: Ephb4 Kinase Domain Inhibitor Complex
148. 2vwu: Ephb4 Kinase Domain Inhibitor Complex
149. 7aym: Structure of Ddr2 Kinase Domain in Complex with Ibz3
150. 7ju6: Structure of Ret Protein Tyrosine Kinase in Complex with Selpercatinib
151. 7ju5: Structure of Ret Protein Tyrosine Kinase in Complex with Pralsetinib
152. 7czf: Crystal Structure of Kaposi Sarcoma Associated Herpesvirus (kshv ) Ghgl in Complex with The Ligand Binding Domian (lbd) of Epha2
153. 7cze: Crystal Structure of Epstein-barr Virus (ebv) Ghgl and in Complex with The Ligand Binding Domian (lbd) of Epha2
154. 7cqe: Crystal Structure of The Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer in Complex with Azd-7762
155. 7b44: Crystal Structure of C-met Bound by Compound S1
156. 7b43: Crystal Structure of C-met Bound by Compound 9
157. 7b42: Crystal Structure of C-met Bound by Compound 8
158. 7b41: Crystal Structure of C-met Bound by Compound 7
159. 7b40: Crystal Structure of C-met Bound by Compound 6
160. 7b3z: Crystal Structure of C-met Bound by Compound 5
161. 7b3w: Crystal Structure of C-met Bound by Compound 4
162. 7b3v: Crystal Structure of C-met Bound by Compound 3
163. 7b3t: Crystal Structure of C-met Bound by Compound 2
164. 7b3q: Crystal Structure of C-met Bound by Compound 1
165. 7azb: Structure of Ddr2 Ds Domain in Complex with Vhh
166. 7ab2: Crystal Structure of Mertk Kinase Domain in Complex with Unc2025
167. 7ab1: Crystal Structure of Mertk Kinase Domain in Complex with Gilteritinib
168. 7ab0: Apo Crystal Structure of The Mertk Kinase Domain
169. 7aaz: Crystal Structure of Mertk in Complex with a Type 1.5 Aminopyridine Inhibitor
170. 7aay: Crystal Structure of Mertk Kinase Domain in Complex with Merestinib
171. 7aax: Crystal Structure of Mertk Kinase Domain in Complex with Ldc1267
172. 7a2a: Crystal Structure of EGFR-T790M/V948R in Complex with Spebrutinib and Eai001
173. 2rl5: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a 2,3-dihydro-1,4-benzoxazine Inhibitor
174. 2rgp: Structure of Egfr in Complex with Hydrazone, a Potent Dual Inhibitor
175. 2rfs: X-ray Structure of Su11274 Bound to C-met
176. 2rfn: X-ray Structure of C-met with Inhibitor.
177. 2rfe: Crystal Structure of The Complex between The Egfr Kinase Domain and a Mig6 Peptide
178. 2rfd: Crystal Structure of The Complex between The Egfr Kinase Domain and a Mig6 Peptide
179. 2rf9: Crystal Structure of The Complex between The Egfr Kinase Domain and a Mig6 Peptide
180. 2rei: Kinase Domain of Human Ephrin Type-a Receptor 7 (epha7)
181. 2r4b: Erbb4 Kinase Domain Complexed with a Thienopyrimidine Inhibitor
182. 2r2p: Kinase Domain of Human Ephrin Type-a Receptor 5 (epha5)
183. 2qu6: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Benzoxazole Inhibitor
184. 2qu5: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Benzimidazole Inhibitor
185. 2qoq: Human Epha3 Kinase and Juxtamembrane Region, Base, Amp-pnp Bound Structure
186. 2qoo: Human Epha3 Kinase and Juxtamembrane Region, Y596F:Y602F:Y742F Triple Mutant
187. 2qon: Human Epha3 Kinase and Juxtamembrane Region, Y596F:Y602F:Y742A Triple Mutant
188. 2qol: Human Epha3 Kinase and Juxtamembrane Region, Y596:Y602:S768G Triple Mutant
189. 2qok: Human Epha3 Kinase and Juxtamembrane Region, Y596F:Y602F:S768A Triple Mutant
190. 2qoi: Human Epha3 Kinase and Juxtamembrane Region, Y596F:Y602F Double Mutant
191. 2qof: Human Epha3 Kinase and Juxtamembrane Region, Y596F Mutant
192. 2qod: Human Epha3 Kinase and Juxtamembrane Region, Y602F Mutant
193. 2qoc: Human Epha3 Kinase Domain, Phosphorylated, Amp-pnp Bound Structure
194. 2qob: Human Epha3 Kinase Domain, Base Structure
195. 2qo9: Human Epha3 Kinase and Juxtamembrane Region, Phosphorylated, Amp-pnp Bound
196. 2qo7: Human Epha3 Kinase and Juxtamembrane Region, Dephosphorylated, Amp-pnp Bound
197. 2qo2: Human Epha3 Kinase and Juxtamembrane Region, Dephosphorylated, Apo Structure
198. 2qkq: Structure of The Sam Domain of Human Ephrin Type-b Receptor 4
199. 2ckn: Nmr Structure of The First Ig Module of Mouse Fgfr1
200. 2qbx: Ephb2/snew Antagonistic Peptide Complex
201. 2q0b: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic E565A Mutation Responsible for Pfeiffer Syndrome
202. 2pzr: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome
203. 2pzp: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic K526E Mutation Responsible for Crouzon Syndrome
204. 2pz5: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic N549T Mutation Responsible for Pfeiffer Syndrome
205. 2py3: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic E565G Mutation Responsible for Pfeiffer Syndrome
206. 2pwl: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic N549H Mutation Responsible for Crouzon Syndrome.
207. 2pvy: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome.
208. 2pvf: Crystal Structure of Tyrosine Phosphorylated Activated Fgf Receptor 2 (fgfr2) Kinase Domain in Complex with Atp Analog and Substrate Peptide
209. 2psq: Crystal Structure of Unphosphorylated Unactivated Wild Type Fgf Receptor 2 (fgfr2) Kinase Domain
210. 2p4i: Evolution of a Highly Selective and Potent 2-(pyridin-2-yl)- 1,3,5-triazine Tie-2 Kinase Inhibitor
211. 2p2i: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Nicotinamide Inhibitor
212. 2p2h: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Pyridinyl-triazine Inhibitor
213. 2p0c: Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer
214. 2osc: Synthesis, Structural Analysis, and Sar Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors
215. 6z4d: Crystal Structure of EGFR-T790M/V948R in Complex with Mavelertinib and Eai001
216. 6z4b: Crystal Structure of EGFR-T790M/V948R in Complex with Osimertinib and Eai045
217. 2oo8: Synthesis, Structural Analysis, and Sar Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors
218. 6yi8: Human Fgfr4 Kinase Domain (447-753) in Complex with Roblitinib
219. 2oh4: Crystal Structure of Vegfr2 with a Benzimidazole-urea Inhibitor
220. 2ogv: Crystal Structure of The Autoinhibited Human C-fms Kinase Domain
221. 6y23: Ddr1 Kinase Autoinhibited by Its Juxtamembrane Region
222. 6c1o: Fgfr1 Kinase Domain Complexed with Fiin-1
223. 6c1c: Fgfr1 Kinase Complex with Inhibitor Sn37116
224. 6c1b: Fgfr1 Kinase Complex with Inhibitor Sn37118
225. 6c19: Fgfr1 Kinase Complex with Inhibitor Sn36985
226. 6c18: Fgfr1 Kinase Complex with Inhibitor Sn37115
227. 6bsd: Ddr1 Bound to Dasatinib
228. 6brj: Ddr1 Bound to Vx-680
229. 6bgt: Structure of Trastuzumab Fab Mutant in Complex with Her2 Extracellular Domain
230. 6b9l: Crystal Structure of Epha2 with Peptide 135e2
231. 2o26: Structure of a Class III Rtk Signaling Assembly
232. 6b3s: Crystal Structure of The Fab Fragment of Necitumumab (FAB11F8) in Complex with Domain III from a Cetuximab Resistant Variant of Egfr (SEGFRD3-S468R)
233. 2e7h: Solution Structure of The Second Fn3 Domain from Human Ephrin Type-b Receptor 4
234. 6att: 39s Fab Bound to Her2 Ecd
235. 2e8n: Solution Structure of The C-terminal Sam-domain of Ephaa2: Ephrin Type-a Receptor 2 Precursor (ec 2.7.10.1)
236. 6aru: Structure of Cetuximab Fab Mutant in Complex with Egfr Extracellular Domain
237. 2e9w: Crystal Structure of The Extracellular Domain of Kit in Complex with Stem Cell Factor (scf)
238. 2eao: Solution Structure of The C-terminal Sam-domain of Mouse Ephrin Type-b Receptor 1 Precursor (ec 2.7.1.112)
239. 2eb2: Crystal Structure of Mutated Egfr Kinase Domain (G719S)
240. 2eb3: Crystal Structure of Mutated Egfr Kinase Domain (L858R) in Complex with Amppnp
241. 2ec8: Crystal Structure of The Exctracellular Domain of The Receptor Tyrosine Kinase, Kit
242. 6agx: The Cocrystal Structure of Fgfr2 Bound with Compound 14 Harboring 5h- Pyrrolo[2,3-b]pyrazine Scaffold
243. 2l4k: Water Refined Solution Structure of The Human Grb7-sh2 Domain in Complex with The 10 Amino Acid Peptide Py1139
244. 6a32: Crystal Structure of Pdgfra Kinase Domain Mutant T674I
245. 5zwj: Crystal Structure of Egfr 675-1022 T790M/C797S/V948R in Complex with Eai045
246. 5zv2: Fgfr-1 in Complex with Ligand Lenvatinib
247. 5zto: Crystal Structure of Egfr 696-1022 T790M/C797S in Complex with D3003
248. 5zrz: Crystal Structure of Epha5/samd5 Complex
249. 5zry: Crystal Structure of Epha6/odin Complex
250. 5zrx: Crystal Structure of Epha2/ship2 Complex
251. 2exe: Crystal Structure of The Phosphorylated Clk3
252. 2gs2: Crystal Structure of The Active Egfr Kinase Domain
253. 2gs6: Crystal Structure of The Active Egfr Kinase Domain in Complex with an Atp Analog-peptide Conjugate
254. 2gs7: Crystal Structure of The Inactive Egfr Kinase Domain in Complex with Amp-pnp
255. 2gsf: The Human Epha3 Receptor Tyrosine Kinase and Juxtamembrane Region
256. 5z0s: Crystal Structure of Fgfr1 Kinase Domain in Complex with a Novel Inhibitor
257. 2gy5: Tie2 Ligand-binding Domain Crystal Structure
258. 2gy7: Angiopoietin-2/tie2 Complex Crystal Structure
259. 5yu9: Crystal Structure of Egfr 696-1022 T790M in Complex with Ibrutinib
260. 6q7e: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with The Nvp-bhg712 Derivative Atdl14
261. 2hen: Crystal Structure of The Ephb2 Receptor Kinase Domain in Complex with Adp
262. 6t2w: Crystal Structure of The CSF1R Kinase Domain with a Dihydropurinone Inhibitor (compound 4)
263. 2hle: Structural and Biophysical Characterization of The Ephb4- Ephrinb2 Protein Protein Interaction and Receptor Specificity.
264. 2i0v: C-fms Tyrosine Kinase in Complex with a Quinolone Inhibitor
265. 2i0y: Cfms Tyrosine Kinase (fgf Kid) in Complex with an Arylamide Inhibitor
266. 2i1m: Cfms Tyrosine Kinase (tie2 Kid) in Complex with an Arylamide Inhibitor
267. 2iep: Crystal Structure of Immunoglobulin-like Domains 1 and 2 of The Receptor Tyrosine Kinase Musk
268. 2ifg: Structure of The Extracellular Segment of Human Trka in Complex with Nerve Growth Factor
269. 2itn: Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Amp-pnp
270. 2ito: Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Iressa
271. 2itp: Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Aee788
272. 2itq: Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Afn941
273. 2itt: Crystal Structure of Egfr Kinase Domain L858R Mutation in Complex with Aee788
274. 2itu: Crystal Structure of Egfr Kinase Domain L858R Mutation in Complex with Afn941
275. 2itv: Crystal Structure of Egfr Kinase Domain L858R Mutation in Complex with Amp-pnp
276. 2itw: Crystal Structure of Egfr Kinase Domain in Complex with Afn941
277. 2itx: Crystal Structure of Egfr Kinase Domain in Complex with Amp- Pnp
278. 2ity: Crystal Structure of Egfr Kinase Domain in Complex with Iressa
279. 2itz: Crystal Structure of Egfr Kinase Domain L858R Mutation in Complex with Iressa
280. 2iui: Crystal Structure of The Pi3-kinase P85 N-terminal Sh2 Domain in Complex with Pdgfr Phosphotyrosyl Peptide
281. 2ivs: Crystal Structure of Non-phosphorylated Ret Tyrosine Kinase Domain
282. 2ivt: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain
283. 2ivu: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with The Inhibitor Zd6474
284. 2ivv: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with The Inhibitor Pp1
285. 2j5e: Crystal Structure of Egfr Kinase Domain in Complex with an Irreversible Inhibitor 13-jab
286. 2j5f: Crystal Structure of Egfr Kinase Domain in Complex with an Irreversible Inhibitor 34-jab
287. 2j6m: Crystal Structure of Egfr Kinase Domain in Complex with Aee788
288. 2jiv: Crystal Structure of Egfr Kinase Domain T790M Mutation in Compex with Hki-272
289. 2jwa: Erbb2 Transmembrane Segment Dimer Spatial Structure
290. 6v6q: Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with Ptr657
291. 6wvz: Crystal Structure of Anti-met Fab Arm of Amivantamab in Complex with Human Met
292. 2k1l: Nmr Structures of Dimeric Transmembrane Domain of The Receptor Tyrosine Kinase Epha1 in Lipid Bicelles at Ph 6.3
293. 6umw: Crystal Structure of Hephb1 Bound with Chlortetracycline
294. 2k9y: Epha2 Dimeric Structure in The Lipidic Bicelle at Ph 5.0
295. 6tg1: Crystal Structure of Egfr T790M/V948R in Complex with Covalent Pyrrolopyrimidine 21b
296. 6tg0: Crystal Structure of Egfr T790M/V948R in Complex with Covalent Pyrrolopyrimidine 21a
297. 6tfz: Crystal Structure of Egfr T790M/V948R in Complex with Covalent Pyrrolopyrimidine 19
298. 6tfy: Crystal Structure of Egfr T790M/V948R in Complex with Covalent Pyrrolopyrimidine 18c
299. 6tfw: Crystal Structure of Egfr T790M/V948R in Complex with Covalent Pyrrolopyrimidine 18d
300. 6tfv: Crystal Structure of Egfr T790M/V948R in Complex with Covalent Pyrrolopyrimidine 18b
301. 6tfu: Crystal Structure of Egfr T790M/V948R in Complex with Covalent Pyrrolopyrimidine 14d
302. 2kgt: Solution Structure of Sh3 Domain of Ptk6
303. 6pl4: Trk-a in Complex with Ligand 1
304. 6lud: Crystal Structure of EGFR(L858R/T790M/C797S) in Complex with Osimertinib
305. 6lub: Crystal Structure of EGFR(L858R/T790M/C797S) in Complex with Ch7233163
306. 2ks1: Heterodimeric Association of Transmembrane Domains of Erbb1 and Erbb2 Receptors Enabling Kinase Activation
307. 6lbx: Crystal Structure of Her2 Domain IV and Rb-h2
308. 6kbi: Crystal Structure of Erbb3 N418Q Mutant
309. 3nru: Ligand Binding Domain of Epha7
310. 3lzb: Egfr Kinase Domain Complexed with an Imidazo[2,1-b]thiazole Inhibitor
311. 6veq: Con-ins G1 in Complex with The Human Insulin Microreceptor in Turn in Complex with Fv 83-7
312. 6vep: Human Insulin in Complex with The Human Insulin Microreceptor in Turn in Complex with Fv 83-7
313. 3p1i: Ligand Binding Domain of Human Ephrin Type-b Receptor 3
314. 6xvk: Crystal Structure of The Kdr (vegfr2) Kinase Domain in Complex with a Type-ii Inhibitor Bearing an Acrylamide
315. 6xvj: Crystal Structure of The Kdr (vegfr2) Kinase Domain in Complex with a Type-ii Inhibitor
316. 6xvb: Crystal Structure of The Kinase Domain of Human C-kit with a Cyclic Imidate Inhibitor Covalently Bound to Cys788
317. 6xva: Crystal Structure of The Kinase Domain of Human C-kit in Complex with a Type-ii Inhibitor Bearing an Acrylamide
318. 6xv9: Crystal Structure of The Kinase Domain of Human C-kit in Complex with a Type-ii Inhibitor
319. 3q6u: Structure of The Apo Met Receptor Kinase in The Dually-phosphorylated, Activated State
320. 3q6w: Structure of Dually-phosphorylated Met Receptor Kinase in Complex with an Mk-2461 Analog with Specificity for The Activated Receptor
321. 2xir: Crystal Structure of The Vegfr2 Kinase Domain in Complex with Pf-00337210 (n,2-dimethyl-6-(7-(2-morpholinoethoxy) Quinolin-4-yloxy)benzofuran-3-carboxamide)
322. 6vwj: Leg Region of The Closed Conformation of The Human Type 1 Insulin-like Growth Factor Receptor Ectodomain in Complex with Human Insulin-like Growth Factor II
323. 6vwi: Head Region of The close Conformation of The Human Type 1 Insulin-like Growth Factor Receptor Ectodomain in Complex with Human Insulin-like Growth Factor Ii.
324. 6vwh: Leg Region of The Open Conformation of The Human Type 1 Insulin-like Growth Factor Receptor Ectodomain in Complex with Human Insulin-like Growth Factor Ii.
325. 6vwg: Head Region of The Open Conformation of The Human Type 1 Insulin-like Growth Factor Receptor Ectodomain in Complex with Human Insulin-like Growth Factor Ii.
326. 3poz: Egfr Kinase Domain Complexed with Tak-285
327. 3pp0: Crystal Structure of The Kinase Domain of Human Her2 (erbb2).
328. 3qqu: Cocrystal Structure of Unphosphorylated Igf with Pyrimidine 8
329. 3qs7: Crystal Structure of a Human Flt3 Ligand-receptor Ternary Complex
330. 3qs9: Crystal Structure of a Human Flt3 Ligand-receptor Ternary Complex
331. 6jpe: Crystal Structure of Fgfr4 Kinase Domain with Irreversible Inhibitor 1
332. 3rhk: Crystal Structure of The Catalytic Domain of C-met Kinase in Complex with Arq 197
333. 2yfx: Structure of L1196M Mutant Anaplastic Lymphoma Kinase in Complex with Crizotinib
334. 3o23: Human Unphosphorylated Igf1-r Kinase Domain in Complex with an Hydantoin Inhibitor
335. 3rhx: Crystal Structure of The Catalytic Domain of Fgfr1 Kinase in Complex with Arq 069
336. 3ri1: Crystal Structure of The Catalytic Domain of Fgfr2 Kinase in Complex with Arq 069
337. 6jxt: Crystal Structure of Egfr 696-1022 Wt in Complex with Azd9291 Prepared by Cocrystallization
338. 6vhp: Wild Type Egfr in Complex with Ln2899
339. 6vhn: Wild Type Egfr in Complex with Ln2057
340. 6vh4: Wild Type Egfr in Complex with Ln2380
341. 6v6o: EGFR(T790M/V948R) in Complex with Ln2380
342. 6v6k: EGFR(T790M/V948R) in Complex with Ln2057
343. 6v66: EGFR(T790M/V948R) in Complex with Ln2899
344. 6v5p: EGFR(T790M/V948R) in Complex with Ln2725
345. 6v5n: EGFR(T790M/V948R) in Complex with Ln2084
346. 2l9u: Spatial Structure of Dimeric Erbb3 Transmembrane Domain
347. 2yhv: Structure of L1196M Mutant Anaplastic Lymphoma Kinase
348. 3aox: X-ray Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with Ch5424802
349. 6jx4: Crystal Structure of Egfr 696-1022 T790M in Complex with Azd9291 Prepared by Soaking
350. 6jx0: Crystal Structure of Egfr 696-1022 T790M in Complex with Azd9291 Prepared by Co-crystallization
351. 6jwl: Crystal Structure of Egfr 696-1022 L858R in Complex with Azd9291
352. 6jrx: Egfr T790M/C797S in Complex with Compound 6i
353. 6jrk: The Structure of Co-crystals of 8r-b-egfr Wt Complex
354. 6jrj: The Structure of Co-crystals of 8r-b-egfr T790M/C797S Complex
355. 2xvd: Ephb4 Kinase Domain Inhibitor Complex
356. 6rw2: Bicycle Toxin Conjugate Bound to Epha2
357. 6lvm: Crystal Structure of Fgfr3 in Complex with Pyrimidine Derivative
358. 6lvl: Crystal Structure of Fgfr2 in Complex with 1,3,5-triazine Derivative
359. 6lvk: Crystal Structure of Fgfr2 in Complex with 1,3,5-triazine Derivative
360. 6osv: Potent and Selective Antitumor Antibody Targeting a Membrane-proximal Epitope of Ror2
361. 6osn: Potent and Selective Antitumor Antibody Targeting a Membrane-proximal Epitope of Ror2
362. 6osh: Potent and Selective Antitumor Antibody Targeting a Membrane-proximal Epitope of Ror2
363. 6v9c: Crystal Structure of Fgfr4 Kinase Domain in Complex with Covalent Inhibitor
364. 6jol: Crystal Structure of Pdgfra in Complex with Imatinib by Co- Crystallization
365. 6jok: Crystal Structure of Pdgfra in Complex with Sunitinib by Soaking
366. 6joj: Crystal Structure of Pdgfra T674I in Complex with Crenolanib by Soaking
367. 6joi: Crystal Structure of Pdgfra T674I in Complex with Crenolanib by Co- Crystallization
368. 3qti: C-met Kinase in Complex with Nvp-bvu972
369. 3rgx: Structural Insight into Brassinosteroid Perception by Bri1
370. 3rgz: Structural Insight into Brassinosteroid Perception by Bri1
371. 3riz: Crystal Structure of The Plant Steroid Receptor Bri1 Ectodomain
372. 3rj0: Plant Steroid Receptor Bri1 Ectodomain in Complex with Brassinolide
373. 6p8q: Egfr in Complex with a Dihydrodibenzodiazepinone Allosteric Inhibitor.
374. 6p1l: Crystal Structure of Egfr in Complex with Eai045
375. 6p1d: Crystal Structure of Egfr with Mutant-selective Dihydrodibenzodiazepinone Allosteric Inhibitor
376. 3s35: Structural Basis for The Function of Two Anti-vegf Receptor Antibodies
377. 3s36: Structural Basis for The Function of Two Anti-vegf Receptor Antibodies
378. 3s37: Structural Basis for The Function of Two Anti-vegf Receptor Antibodies
379. 3oj2: Crystal Structure of Fgf1 Complexed with The Ectodomain of FGFR2B Harboring The A172F Pfeiffer Syndrome Mutation
380. 3ojm: Crystal Structure of Fgf1 Complexed with The Ectodomain of FGFR2B Harboring P253R Apert Mutation
381. 3skj: Structural and Functional Characterization of an Agonistic Anti-human Epha2 Monoclonal Antibody
382. 3zxz: X-ray Structure of Pf-04217903 Bound to The Kinase Domain of C-met
383. 2l2t: Solution Nmr Structure of The Erbb4 Dimeric Membrane Domain
384. 3zze: Crystal Structure of C-met Kinase Domain in Complex with N'- ((3z)-4-chloro-7-methyl-2-oxo-1,2-dihydro-3h-indol-3- Ylidene)-2-(4-hydroxyphenyl)propanohydrazide
385. 3zzw: Crystal Structure of The Kinase Domain of Ror2
386. 6sof: Human Insulin Receptor Ectodomain Bound by 4 Insulin
387. 6sde: Crystal Structure of Wild-type Cmet Bound by Savolitinib
388. 6sdd: Crystal Structure of D1228V Cmet Bound by Bms-777607
389. 6sdc: Crystal Structure of D1228V Cmet Bound by Foretinib
390. 6sd9: Crystal Structure of Wild-type Cmet Bound by Foretinib
391. 6s9d: Egfr-kinase in Complex with Compound 6
392. 6s9c: Egfr-kinase in Complex with Compound 5
393. 6s9b: Egfr-kinase in Complex with Compound 1
394. 6s8a: Crystal Structure of EGFR-T790M/C797S in Complex with Covalent Pyrrolopyrimidine 19h
395. 6s89: Crystal Structure of EGFR-T790M/C797S in Complex with Covalent Pyrrolopyrimidine 19g
396. 3p0y: Anti-egfr/her3 Fab Dl11 in Complex with Domain III of Egfr Extracellular Region
397. 3p11: Anti-egfr/her3 Fab Dl11 in Complex with Domains I-iii of The Her3 Extracellular Region
398. 2y6m: Crystal Structure of Epha4 Kinase Domain
399. 2y6o: Crystal Structure of Epha4 Kinase Domain in Complex with Dasatinib.
400. 3u2p: Crystal Structure of N-terminal Three Extracellular Domains of Erbb4/her4
401. 3vhe: Crystal Structure of Human Vegfr2 Kinase Domain with a Novel Pyrrolopyrimidine Inhibitor.
402. 3rcd: Her2 Kinase Domain Complexed with Tak-285
403. 2xyu: Crystal Structure of Epha4 Kinase Domain in Complex with Vuf 12058
404. 3qup: Inhibitor Bound Structure of The Kinase Domain of The Murine Receptor Tyrosine Kinase Tyro3 (sky)
405. 6r1h: Crystal Structure of The Lrr Ectodomain of The Receptor Kinase Sobir1 from Arabidopsis Thaliana.
406. 6pma: Trk-a in Complex with Ligand
407. 6pmb: Trk-a in Complex with Ligand 1a
408. 3ojv: Crystal Structure of Fgf1 Complexed with The Ectodomain of FGFR1C Exhibiting an Ordered Ligand Specificity-determining Betac'-betae Loop
409. 3tl8: The Avrptob-bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains in a Single Type III Effector
410. 3v2a: Vegfr-2/vegf-a Complex Structure
411. 3v6b: Vegfr-2/vegf-e Complex Structure
412. 6q2s: Cryo-em Structure of Ret/gfra3/artn Extracellular Complex. The 3d Refinement Was Applied with C2 Symmetry.
413. 6q2r: Cryo-em Structure of Ret/gfra2/nrtn Extracellular Complex in The Tetrameric Form
414. 6q2o: Cryo-em Structure of Ret/gfra2/nrtn Extracellular Complex. The 3d Refinement Was Applied with C2 Symmetry.
415. 6q2n: Cryo-em Structure of Ret/gfra1/gdnf Extracellular Complex
416. 6q2j: Cryo-em Structure of Extracellular Dimeric Complex of Ret/gfral/gdf15
417. 6pyh: Cryo-em Structure of Full-length IGF1R-IGF1 Complex. Only The Extracellular Region of The Complex Is Resolved.
418. 6pxw: Cryo-em Structure of Full-length Insulin Receptor Bound to 4 Insulin. 3d Refinement Was Focused on The Top part of The Receptor Complex.
419. 6pxv: Cryo-em Structure of Full-length Insulin Receptor Bound to 4 Insulin. 3d Refinement Was Focused on The Extracellular Region.
420. 3qwq: Crystal Structure of The Extracellular Domain of The Epidermal Growth Factor Receptor in Complex with an Adnectin
421. 3r7o: Structure of Dually Phosphorylated C-met in Complex with Mk-2461
422. 3v5q: Discovery of a Selective Trk Inhibitor with Efficacy in Rodent Cancer Tumor Models
423. 4dce: Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with a Piperidine-carboxamide Inhibitor
424. 6pl3: Trk-a in Complex with Ligand 2a
425. 6pl2: Trk-a in Complex with Ligand 1a
426. 6pl1: Trk-a in Complex with Ligand 1b
427. 3u6h: Crystal Structure of C-met in Complex with Pyrazolone Inhibitor 26
428. 3u6i: Crystal Structure of C-met in Complex with Pyrazolone Inhibitor 58a
429. 3u6j: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Pyrazolone Inhibitor
430. 6p69: Crystal Structure of FGFR1-Y563C (fgfr4 Surrogate) Covalently Bound to Compound 11.
431. 6p68: Crystal Structure of FGFR1-Y563C (fgfr4 Surrogate) Covalently Bound to Compound 22.
432. 3ug1: Crystal Structure of The Mutated Egfr Kinase Domain (G719S/T790M) in The Apo Form
433. 3ug2: Crystal Structure of The Mutated Egfr Kinase Domain (G719S/T790M) in Complex with Gefitinib
434. 6op9: Her3 Pseudokinase Domain Bound to Bosutinib
435. 3vjn: Crystal Structure of The Mutated Egfr Kinase Domain (G719S/T790M) in Complex with Amppnp.
436. 3vjo: Crystal Structure of The Wild-type Egfr Kinase Domain in Complex with Amppnp.
437. 6oge: Cryo-em Structure of Her2 Extracellular Domain-trastuzumab Fab- Pertuzumab Fab Complex
438. 3vnt: Crystal Structure of The Kinase Domain of Human Vegfr2 with a [1, 3]thiazolo[5,4-b]pyridine Derivative
439. 4dkd: Crystal Structure of Human Interleukin-34 Bound to Human Csf-1r
440. 4ag4: Crystal Structure of a Ddr1-fab Complex
441. 6nvl: Fgfr1 Complex with N-(2-((5-((2,6-dichloro-3,5-dimethoxybenzyl)oxy) Pyrimidin-2-yl)amino)-3-methylphenyl)acrylamide
442. 6nvk: Fgfr4 Complex with Blu-554, N-((3s,4s)-3-((6-(2,6-dichloro-3,5- Dimethoxyphenyl)quinazolin-2-yl)amino)tetrahydro-2h-pyran-4-yl) Acrylamide
443. 6nvj: Fgfr4 Complex with N-(2-((5-((2,6-dichloro-3,5-dimethoxybenzyl)oxy) Pyrimidin-2-yl)amino)-3-fluorophenyl)acrylamide
444. 6nvi: Fgfr4 Complex with N-(3-chloro-2-((5-((2,6-dichloro-3,5- Dimethoxybenzyl)oxy)pyrimidin-2-yl)amino)-5-fluorophenyl)acrylamide
445. 6nvh: Fgfr4 Complex with N-(2-((5-((2,6-dichloro-3,5-dimethoxybenzyl)oxy) Pyrimidin-2-yl)amino)-3-methylphenyl)acrylamide
446. 6nvg: Fgfr4 Complex with N-(3,5-dichloro-2-((5-((2,6-dichloro-3,5- Dimethoxybenzyl)oxy)pyrimidin-2-yl)amino)phenyl)acrylamide
447. 6nss: Trk-a in Complex with Ligand 6
448. 6nsp: Trk-a in Complex with Ligand 9
449. 6npt: Trk-a in Complex with Ligand 1
450. 6nkp: Epha2 Lbd in Complex with Ba-wla-yskbio Peptide
451. 6nk2: Epha2 Lbd in Complex with Ba-wla-yrpk Bio Peptide
452. 6nk1: Epha2 Lbd in Complex with Ba-wla-yrpkbio Peptide
453. 6nk0: Epha2 Lbd in Complex with Ba-wla-yam Peptide
454. 6njz: Epha2 Lbd in Complex with Ysa-gsgsk-bio Peptide
455. 6vhg: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with a Pyrazolo[1,5-a]pyrimidine Inhibitor
456. 6nja: Structure of Wt Ret Protein Tyrosine Kinase Domain at 1.92a Resolution.
457. 2lcx: Spatial Structure of The Erbb4 Dimeric Tm Domain
458. 6nec: Structure of Ret Protein Tyrosine Kinase Domain in Complex with Nintedanib
459. 6ne7: Structure of G810A Mutant of Ret Protein Tyrosine Kinase Domain.
460. 3uim: Structural Basis for The Impact of Phosphorylation on Plant Receptor- like Kinase Bak1 Activation
461. 2l6w: Pdgfr Beta-tm
462. 4deg: Crystal Structure of C-met in Complex with Triazolopyridazine Inhibitor 2
463. 4deh: Crystal Structure of C-met in Complex with Triazolopyridinone Inhibitor 3
464. 4dei: Crystal Structure of C-met in Complex with Triazolopyridinone Inhibitor 24
465. 4exp: Structure of Mouse Interleukin-34 in Complex with Mouse Fms
466. 6n33: Crystal Structure of Fms Kinase Domain with a Small Molecular Inhibitor, Plx5622
467. 2yjr: Structure of F1174L Mutant Anaplastic Lymphoma Kinase
468. 2yjs: Structure of C1156Y Mutant Anaplastic Lymphoma Kinase
469. 3tt0: Co-structure of Fibroblast Growth Factor Receptor 1 Kinase Domain with 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1- Yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (bgj398)
470. 6mzw: Tas-120 Covalent Complex with Fgfr1
471. 6mzq: Tas-120 in Reversible Binding Mode with Fgfr1
472. 6mx8: Crystal Structure of Anaplastic Lymphoma Kinase (alk) Bound by Brigatinib
473. 6mwe: Crystal Structure of Tie2 in Complex with Decipera Compound Dp1919
474. 4f63: Crystal Structure of Human Fibroblast Growth Factor Receptor 1 Kinase Domain in Complex with Compound 1
475. 4f64: Crystal Structure of Human Fibroblast Growth Factor Receptor 1 Kinase Domain in Complex with Compound 6
476. 4f65: Crystal Structure of Human Fibroblast Growth Factor Receptor 1 Kinase Domain in Complex with Compound 8
477. 3tcp: Crystal Structure of The Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer in Complex with Inhibitor Unc569
478. 6mob: Crystal Structure of Kit1 in Complex with Dp2976 via Co- Crystallization
479. 6mep: Crystal Structure of The Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer in Complex with Inhibitor Unc3437
480. 4fob: Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with Acyliminobenzimidazole Inhibitor 1
481. 4foc: Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with Acyliminobenzimidazole Inhibitor 2
482. 4fod: Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with Acyliminobenzimidazole Inhibitor 36
483. 6kzd: Crystal Structure of Trkc in Complex with 3-((6-(4-aminophenyl) Imidazo[1,2-a]pyrazin-3-yl)ethynyl)- N-(3-isopropyl-5-((4- Methylpiperazin-1-yl)methyl)phenyl)-2- Methylbenzamide
484. 6kzc: Crystal Structure of Trkc in Complex with 3-(imidazo[1,2-a]pyrazin-3- Ylethynyl)-2-methyl-n-(3-((4- Methylpiperazin-1-yl)methyl)-5- (trifluoromethyl)phenyl)benzamide
485. 4aw5: Complex of The Ephb4 Kinase Domain with an Oxindole Inhibitor
486. 6kla: Crystal Structure of Human C-kit Kinase Domain in Complex with Compound 15a
487. 4fww: Crystal Structure of The Sema-psi Extracellular Domains of Human Ron Receptor Tyrosine Kinase
488. 3vid: Crystal Structure of Human Vegfr2 Kinase Domain with Compound A.
489. 4aoj: Human Trka in Complex with The Inhibitor Az-23
490. 4asz: Crystal Structure of Apo Trkb Kinase Domain
491. 4at3: Crystal Structure of Trkb Kinase Domain in Complex with CPD5N
492. 4at4: Crystal Structure of Trkb Kinase Domain in Complex with Ex429
493. 4at5: Crystal Structure of Trkb Kinase Domain in Complex with Gw2580
494. 6jz0: Crystal Structure of Egfr Kinase Domain in Complex with Compound 78
495. 6jqr: Crystal Structure of Flt3 in Complex with Gilteritinib
496. 6jpj: Crystal Structure of Fgf401 in Complex of Fgfr4
497. 3u7u: Crystal Structure of Extracellular Region of Human Epidermal Growth Factor Receptor 4 in Complex with Neuregulin-1 Beta
498. 3vhk: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Back Pocket Binder
499. 4ag8: Crystal Structure of The Vegfr2 Kinase Domain in Complex with Axitinib (ag-013736) (n-methyl-2-(3-((e)-2-pyridin-2- Yl-vinyl)-1h-indazol-6-ylsulfanyl)-benzamide)
500. 4agc: Crystal Structure of Vegfr2 (juxtamembrane and Kinase Domains) in Complex with Axitinib (ag-013736) (n-methyl-2-( 3-((e)-2-pyridin-2-yl-vinyl)-1h-indazol-6-ylsulfanyl)- Benzamide)
501. 4agd: Crystal Structure of Vegfr2 (juxtamembrane and Kinase Domains) in Complex with Sunitinib (su11248) (n-2- Diethylaminoethyl)-5-((z)-(5-fluoro-2-oxo-1h-indol-3- Ylidene)methyl)-2,4-dimethyl-1h-pyrrole-3-carboxamide)
502. 4aoi: Crystal Structure of C-met Kinase Domain in Complex with 4-( 3-((1h- Pyrrolo(2,3-b)pyridin-3-yl)methyl)-(1,2,4)triazolo( 4,3-b)(1,2,4) Triazin-6-yl)benzonitrile
503. 4ap7: Crystal Structure of C-met Kinase Domain in Complex with 4-( (6-(4- Fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin-3-yl)methyl) Phenol
504. 4asd: Crystal Structure of Vegfr2 (juxtamembrane and Kinase Domains) in Complex with Sorafenib (bay 43-9006)
505. 4ase: Crystal Structure of Vegfr2 (juxtamembrane and Kinase Domains) in Complex with Tivozanib (av-951)
506. 6j71: Hua21-scfv in Complex with The Extracellular Domain(ecd) of Her2
507. 6j6y: Fgfr4 D2 - Fab Complex
508. 4f0i: Crystal Structure of Apo Trka
509. 6j5l: Crystal Structure of Trk-a in Complex with The Pan-trk Kinase Inhibitor, Compound 10e
510. 4fnw: Crystal Structure of The Apo F1174L Anaplastic Lymphoma Kinase Catalytic Domain
511. 4fnx: Crystal Structure of The Apo R1275Q Anaplastic Lymphoma Kinase Catalytic Domain
512. 4fny: Crystal Structure of The R1275Q Anaplastic Lymphoma Kinase Catalytic Domain in Complex with a Benzoxazole Inhibitor
513. 4fnz: Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with Piperidine-carboxamide Inhibitor 2
514. 4g5j: Crystal Structure of Egfr Kinase in Complex with Bibw2992
515. 4g5p: Crystal Structure of Egfr Kinase T790M in Complex with Bibw2992
516. 4gt4: Structure of Unliganded, Inactive Ror2 Kinase Domain
517. 4gt5: Crystal Structure of The Inactive Trka Kinase Domain
518. 6iup: Crystal Structure of Fgfr4 Kinase Domain in Complex with Compound 5
519. 6iuo: Crystal Structure of Fgfr4 Kinase Domain in Complex with a Covalent Inhibitor
520. 6itv: Crystal Structure of Activated C-kit in Complex with Compound
521. 6itt: Crystal Structure of Unactivated C-kit in Complex with Compound
522. 6itj: Crystal Structure of Fgfr1 Kinase Domain in Complex with Compound 3
523. 6in0: Crystal Structure of Epha3 in Complex with 18-crown-6
524. 6il3: Crystal Structure of The Flt3 Kinase Bound to a Small Molecule Inhibitor
525. 4gg5: Crystal Structure of Cmet in Complex with Novel Inhibitor
526. 4gg7: Crystal Structure of Cmet in Complex with Novel Inhibitor
527. 6ig8: Crystal Structure of Csf-1r Kinase Domain with a Small Molecular Inhibitor, Jte-952
528. 3u9u: Crystal Structure of Extracellular Domain of Human Erbb4/her4 in Complex with The Fab Fragment of Mab1479
529. 4g2f: Human Epha3 Kinase Domain in Complex with Compound 7
530. 6i04: Crystal Structure of Sema Domain of The Met Receptor in Complex with Fab
531. 3ulz: Crystal Structure of Apo Bak1
532. 4hjo: Crystal Structure of The Inactive Egfr Tyrosine Kinase Domain with Erlotinib
533. 4hwu: Crystal Structure of The Ig-c2 Type 1 Domain from Mouse Fibroblast Growth Factor Receptor 2 (fgfr2) [nysgrc-005912]
534. 3w11: Insulin Receptor Ectodomain Construct Comprising Domains L1-cr in Complex with Human Insulin, Alpha-ct Peptide(704-719) and Fab 83-7
535. 3w12: Insulin Receptor Ectodomain Construct Comprising Domains L1-cr in Complex with High-affinity Insulin Analogue [d-pro-b26]-dti-nh2, Alpha-ct Peptide(704-719) and Fab 83-7
536. 3w13: Insulin Receptor Ectodomain Construct Comprising Domains L1-cr in Complex with High-affinity Insulin Analogue [d-pro-b26]-dti-nh2, Alphact Peptide(693-719) and Fab 83-7
537. 3w2o: Egfr Kinase Domain T790M/L858R Mutant with Tak-285
538. 3w2p: Egfr Kinase Domain T790M/L858R Mutant with Compound 2
539. 3w2q: Egfr Kinase Domain T790M/L858R Mutant with Hki-272
540. 3w2r: Egfr Kinase Domain T790M/L858R Mutant with Compound 4
541. 3w2s: Egfr Kinase Domain with Compound4
542. 4bb4: Ephb4 Kinase Domain Inhibitor Complex
543. 4gk2: Human Epha3 Kinase Domain in Complex with Ligand 66
544. 4gk3: Human Epha3 Kinase Domain in Complex with Ligand 87
545. 4gk4: Human Epha3 Kinase Domain in Complex with Ligand 90
546. 6hp9: Structure of The Kinase Domain of Human Ddr1 in Complex with a 2- Amino-2,3-dihydro-1h-indene-5-carboxamide-based Inhibitor
547. 6hn5: Leucine-zippered Human Insulin Receptor Ectodomain with Single Bound Insulin - "upper" Membrane-distal part
548. 6hn4: Leucine-zippered Human Insulin Receptor Ectodomain with Single Bound Insulin - "lower" Membrane-proximal part
549. 4i1z: Crystal Structure of The Monomeric (V948R) Form of The Gefitinib/erlotinib Resistant Egfr Kinase Domain L858R+T790M
550. 4i20: Crystal Structure of Monomeric (V948R) Primary Oncogenic Mutant L858R Egfr Kinase Domain
551. 4i21: Crystal Structure of L858R + T790M Egfr Kinase Domain in Complex with Mig6 Peptide
552. 4i22: Structure of The Monomeric (V948R)GEFITINIB/ERLOTINIB Resistant Double Mutant (L858R+T790M) Egfr Kinase Domain Co-crystallized with Gefitinib
553. 4i23: Crystal Structure of The Wild-type Egfr Kinase Domain in Complex with Dacomitinib (soaked)
554. 4i24: Structure of T790M Egfr Kinase Domain Co-crystallized with Dacomitinib
555. 6hh1: Structure of C-kit with Allosteric Inhibitor 3g8
556. 6hey: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with The Nvp-bhg712 Derivative Atnk002
557. 3vo3: Crystal Structure of The Kinase Domain of Human Vegfr2 with Imidazo[1, 2-b]pyridazine Derivative
558. 3vrp: Crystal Structure of The Tyrosine Kinase Binding Domain of Cbl-c in Complex with Phospho-egfr Peptide
559. 3vrr: Crystal Structure of The Tyrosine Kinase Binding Domain of Cbl-c (pl Mutant) in Complex with Phospho-egfr Peptide
560. 3w32: Egfr Kinase Domain Complexed with Compound 20a
561. 3w33: Egfr Kinase Domain Complexed with Compound 19b
562. 4anl: Structure of G1269A Mutant Anaplastic Lymphoma Kinase
563. 4anq: Structure of G1269A Mutant Anaplastic Lymphoma Kinase in Complex with Crizotinib
564. 4ans: Structure of L1196M,G1269A Double Mutant Anaplastic Lymphoma Kinase in Complex with Crizotinib
565. 4eev: Crystal Structure of C-met in Complex with Ly2801653
566. 4feq: Inhibitor Bound Structure of The Kinase Domain of The Murine Receptor Tyrosine Kinase Tyro3 (sky)
567. 4ff8: Inhibitor Bound Structure of The Kinase Domain of The Murine Receptor Tyrosine Kinase Tyro3 (sky)
568. 6gwr: Structure of The Kinase Domain of Human Ddr1 in Complex with a Potent and Selective Inhibitor of Ddr1 and Ddr2
569. 4hvs: Crystal Structure of Kit Kinase Domain with a Small Molecule Inhibitor, Plx647
570. 4hw7: Crystal Structure of Fms Kinase Domain with a Small Molecular Inhibitor, Plx647-ome
571. 6gqq: Crystal Structure of Human Kdr (vegfr2) Kinase Domain in Complex with Azd3229-analogue (compound 35)
572. 6gqp: Crystal Structure of Human Kdr (vegfr2) Kinase Domain in Complex with Azd3229-analogue (compound 23)
573. 6gqo: Crystal Structure of Human Kdr (vegfr2) Kinase Domain in Complex with Azd3229-analogue (compound 18)
574. 6gqm: Crystal Structure of Human C-kit Kinase Domain in Complex with a Small Molecule Inhibitor, Azd3229
575. 6gql: Crystal Structure of Human C-kit Kinase Domain in Complex with Azd3229-analogue (compound 35)
576. 6gqk: Crystal Structure of Human C-kit Kinase Domain in Complex with Azd3229-analogue (compound 23)
577. 6gqj: Crystal Structure of Human C-kit Kinase Domain in Complex with Azd3229-analogue (compound 18)
578. 6gl7: Neurturin-gfra2-ret Extracellular Complex
579. 3zos: Structure of The Ddr1 Kinase Domain in Complex with Ponatinib
580. 6gcu: Met Receptor in Complex with Inlb Internalin Domain and Darpin A3A
581. 6tua: The Ryk Pseudokinase Domain
582. 3zbf: Structure of Human Ros1 Kinase Domain in Complex with Crizotinib
583. 4bkj: Crystal Structure of The Human Ddr1 Kinase Domain in Complex with Imatinib
584. 4et7: Crystal Structure of Eph Receptor 5
585. 6fnm: Crystal Structure of Ephrin B4 (ephb4) Receptor Protein Kinase with Dasatinib
586. 6fnl: Crystal Structure of Ephrin B4 (ephb4) Receptor Protein Kinase
587. 6fnk: Crystal Structure of Ephrin B4 (ephb4) Receptor Protein Kinase with a Pyrazolo[3,4-d]pyrimidine Fragment of Nvp-bhg712
588. 6fnj: Crystal Structure of Ephrin B4 (ephb4) Receptor Protein Kinase with an Isomer of Nvp-bhg712
589. 6fni: Crystal Structure of Ephrin B4 (ephb4) Receptor Protein Kinase with Nvp-bhg712
590. 6fnh: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with a Pyrazolo[3,4-d]pyrimidine Fragment of Nvp-bhg712
591. 6fng: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with an Isomer of Nvp-bhg712
592. 6fnf: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Nvp-bhg712
593. 6fiq: Ddr1, 1-(1h-indazole-5-carbonyl)-5'-methoxy-1'-[2-oxo-2-[(2s)-2- (trifluoromethyl)pyrrolidin-1-yl]ethyl]spiro[piperidine-4,3'- Pyrrolo[3,2-b]pyridine]-2'-one, 1.790a, P212121, Rfree=23.8%
594. 6fio: Ddr1, 2-[1'-(1h-indazole-5-carbonyl)-4-methyl-2-oxospiro[indole-3,4'- Piperidine]-1-yl]-n-(2,2,2-trifluoroethyl)acetamide, 1.990a, P6522, Rfree=27.7%
595. 6fin: Ddr1, 3-[(3-cyclopropyl-1,2,4-oxadiazol-5-yl)methyl]-8-(1h-indazole-5- Carbonyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, 1.670a, P1211, Rfree=22.8%
596. 6fil: Ddr1, 2-[8-(1h-indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8- Triazaspiro[4.5]decan-3-yl]-n-methylacetamide, 1.730a, P212121, Rfree=24.5%
597. 6fif: Crystal Structure of The Bri1 Gly644-asp (bri1-6) Mutant from Arabidopsis Thaliana.
598. 6fg8: Crystal Structure of The Bir3 - Serk1 Complex from Arabidopsis Thaliana.
599. 6fex: Ddr1, 2-[4-bromo-2-oxo-1'-(1h-pyrazolo[4,3-b]pyridine-5-carbonyl) Spiro[indole-3,4'-piperidine]-1-yl]-n-(2,2,2-trifluoroethyl) Acetamide, 1.291a, P212121, Rfree=17.4%
600. 6few: Ddr1, 2-[8-(1h-indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8- Triazaspiro[4.5]decan-3-yl]-n-methylacetamide, 1.440a, P1211, Rfree=24.1%
601. 6fer: Crystal Structure of Human Ddr2 Kinase in Complex with 2-[4,5- Difluoro-2-oxo-1'-(1h-pyrazolo[3,4-b]pyridine-5-carbonyl) Spiro[indole-3,4'-piperidine]-1-yl]-n-(2,2,2-trifluoroethyl)acetamide
602. 6fek: Oncogenic Point Mutation of Ret Receptor Tyrosine Kinase
603. 4jq7: Crystal Structure of Egfr Kinase Domain in Complex with Compound 2a
604. 4jq8: Crystal Structure of Egfr Kinase Domain in Complex with Compound 4b
605. 4jr3: Crystal Structure of Egfr Kinase Domain in Complex with Compound 3g
606. 4jrv: Crystal Structure of Egfr Kinase Domain in Complex with Compound 4c
607. 6f7n: Nmr Structure of Epha2-sam Stapled Peptides (S13STSHORT)
608. 6f7m: Nmr Structure of Epha2-sam Stapled Peptides (S13ST)
609. 4bk4: Crystal Structure of The Human Epha4 Ectodomain
610. 4bk5: Crystal Structure of The Human Epha4 Ectodomain in Complex with Human Ephrin A5 (amine-methylated Sample)
611. 4bka: Crystal Structure of The Human Epha4 Ectodomain in Complex with Human Ephrin A5
612. 4bkf: Crystal Structure of The Human Epha4 Ectodomain in Complex with Human Ephrinb3
613. 6q7d: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with The Nvp-bhg712 Derivative Atdl13
614. 4joa: Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with 7-azaindole Based Inhibitor
615. 4leo: Crystal Structure of Anti-her3 Fab Rg7116 in Complex with The Extracellular Domains of Human Her3 (erbb3)
616. 4bsj: Crystal Structure of Vegfr-3 Extracellular Domains D4-5
617. 4bsk: Crystal Structure of Vegf-c in Complex with Vegfr-3 Domains D1-2
618. 6edl: Halk in Complex with Compound 1 (s)-n-(1-(2,4-difluorophenyl)ethyl)-3- (3-methyl-1h-pyrazol-5-yl)imidazo[1,2-b]pyridazin-6-amine
619. 6ebw: Halk in Complex with Compound 9 (6-(((1s)-1-(5-fluoropyridin-2-yl) Ethyl)amino)-1-(3-methyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-3- Yl)(morpholin-4-yl)methanone
620. 4j95: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome in Space Group C2.
621. 4j96: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic Gain-of-function K659M Mutation Identified in Cervical Cancer.
622. 4j97: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic Gain-of-function K659E Mutation Identified in Endometrial Cancer.
623. 4j98: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Gain-of-function K659Q Mutation.
624. 4j99: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Gain-of-function K659T Mutation.
625. 2lzl: FGFR3TM
626. 2m0b: Homodimeric Transmembrane Domain of The Human Receptor Tyrosine Kinase Erbb1 (egfr, Her1) in Micelles
627. 6e0r: Halk in Complex with Compound 7 N-((1s)-1-(5-fluoropyridin-2-yl) Ethyl)-1-(5-methyl-1h-pyrazol-3-yl)-3-(oxetan-3-ylsulfonyl)-1h- Pyrrolo[2,3-b]pyridin-6-amine
628. 2m59: Spatial Structure of Dimeric Vegfr2 Membrane Domain in Dpc Micelles
629. 6duk: Egfr with an Allosteric Inhibitor
630. 2met: Nmr Spatial Structure of The Trimeric Mutant Tm Domain of Vegfr2 Receptor.
631. 2meu: Nmr Spatial Structure of Mutant Dimeric Tm Domain of Vegfr2 Receptor
632. 2mfq: Nmr Solution Structures of FRS2A Ptb Domain with Neurotrophin Receptor Trkb
633. 2mfr: Solution Structure of The Transmembrane Domain of The Insulin Receptor in Micelles
634. 6dkw: Crystal Structure of Trk-a in Complex with The Pan-trk Kinase Inhibitor, Compound 3.
635. 6dki: Crystal Structure of Trk-a in Complex with The Pan-trk Kinase Inhibitor, Compound 19.
636. 6dkg: Crystal Structure of Trk-a in Complex with The Pan-trk Kinase Inhibitor, Compound 13b.
637. 6dkb: Crystal Structure of Trk-a in Complex with The Pan-trk Kinase Inhibitor, Compound 10b.
638. 6d8e: Discovery of a Highly Potent and Broadly Effective Egfr and Her2 Exon 20 Insertion Mutant Inhibitor
639. 2yn8: Ephb4 Kinase Domain Inhibitor Complex
640. 6d22: Crystal Structure of Tyrosine-protein Kinase Receptor
641. 6d20: Crystal Structure of Tyrosine-protein Kinase Receptor in Complex with 5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3h)-one and 5-{[2,4- Dichloro-5-(pyridin-2-yl)benzene-1-carbonyl]amino}-n-(2-hydroxy-2- Methylpropyl)-1-phenyl-1h-pyrazole-3-carboxamide Inhibitors
642. 6d1z: Crystal Structure of Tyrosine-protein Kinase Receptor in Complex with 5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3h)-one Inhibitor
643. 6d1y: Crystal Structure of Tyrosine-protein Kinase Receptor in Complex with 2,4-dichloro-n-(3-methyl-1-phenyl-1h-pyrazol-5-yl)benzamide Inhibitor
644. 3vw8: Crystal Structure of Human C-met Kinase Domain with Its Inhibitor
645. 3zbx: X-ray Structure of C-met Kinase in Complex with Inhibitor 6- ((6-(4-fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin- 3-yl)methyl)quinoline.
646. 3zc5: X-ray Structure of C-met Kinase in Complex with Inhibitor ( S)-6-(1-(6-(1-methyl-1h-pyrazol-4-yl)-(1,2,4)triazolo(4,3- B)pyridazin-3-yl)ethyl)quinoline.
647. 3zcl: X-ray Structure of C-met Kinase in Complex with Inhibitor ( S)-3-(1-(1h-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-n-isopropyl-( 1,2,4)triazolo(4,3-b)pyridazin-6-amine
648. 3zew: Crystal Structure of Ephb4 in Complex with Staurosporine
649. 3zfm: Crystal Structure of Ephb2
650. 3zfx: Crystal Structure of Ephb1
651. 3zfy: Crystal Structure of Ephb3
652. 6ceb: Insulin Receptor Ectodomain in Complex with Two Insulin Molecules - C1 Symmetry
653. 6ce9: Insulin Receptor Ectodomain in Complex with Two Insulin Molecules
654. 6ce7: Insulin Receptor Ectodomain in Complex with One Insulin Molecule
655. 6cdt: Structure of Human Anaplastic Lymphoma Kinase Domain
656. 6pnx: Crystal Structure of an Asymmetric Dimer of Fgf Receptor 3 Kinases Trapped in A-loop Tyrosine Transphosphorylation Reaction
657. 4ccb: Structure of The Human Anaplastic Lymphoma Kinase in Complex with 3-((r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl) Phenyl)ethoxy)-5-(5-methyl-1h-pyrazol-4-yl)pyridin-2-amine
658. 4ccu: Structure of The Human Anaplastic Lymphoma Kinase in Complex with 2-(5-(6-amino-5-((r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl) Phenyl)ethoxy)pyridin-3-yl)-4-methylthiazol-2-yl)propan-2-ol
659. 4cd0: Structure of L1196M Mutant Human Anaplastic Lymphoma Kinase in Complex with 2-(5-(6-amino-5-((r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl) Phenyl)ethoxy)pyridin-3-yl)-4-methylthiazol-2-yl)propane-1,2-diol
660. 4cki: Crystal Structure of Oncogenic Ret Tyrosine Kinase M918T Bound to Adenosine
661. 4ckj: Crystal Structure of Ret Tyrosine Kinase Domain Bound to Adenosine
662. 4ckr: Crystal Structure of The Human Ddr1 Kinase Domain in Complex with Ddr1-in-1
663. 6pmc: Trk-a in Complex with Ligand 1a
664. 6pme: Trk-a in Complex with Ligand
665. 4cli: Structure of The Human Anaplastic Lymphoma Kinase in Complex with Pf-06463922 ((10r)-7-amino-12-fluoro-2,10,16-trimethyl-15 -oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo(4,3-h) (2,5,11)benzoxadiazacyclotetradecine-3-carbonitrile).
666. 4clj: Structure of L1196M Mutant Human Anaplastic Lymphoma Kinase in Complex with Pf-06463922 ((10r)-7-amino-12-fluoro-2,10, 16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno) Pyrazolo(4,3-h)(2,5,11)benzoxadiazacyclotetradecine-3- Carbonitrile).
667. 4cmo: Structure of The Human Anaplastic Lymphoma Kinase in Complex with The Inhibitor 2-((1r)-1-((3-amino-6-(2- Methoxypyridin- -yl)pyrazin-2-yl)oxy)ethyl)-4-fluoro-n-methylbenzamide
668. 4cmt: Structure of The Human Anaplastic Lymphoma Kinase in Complex with The Inhibitor 3-((1r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl) Phenyl)ethoxy)-5-(3-(methylsulfonyl)phenyl)pyridin-2-amine
669. 4cmu: Structure of The Human Anaplastic Lymphoma Kinase in Complex with The Inhibitor (10r)-7-amino-12-fluoro-1,3,10, 16-tetramethyl-16,17-dihydro-1h-8,4-(metheno)pyrazolo(4,3- H)(2,5,11)benzoxadiazacyclotetradecin-15(10h)-one
670. 4cnh: Structure of The Human Anaplastic Lymphoma Kinase in Complex with The Inhibitor 3-((1r)-1-(5-fluoro-2- Methoxyphenyl)ethoxy)-5-(1-methyl-1h-1,2,3-triazol-5-yl) Pyridin-2-amine
671. 4ctb: Structure of The Human Anaplastic Lymphoma Kinase in Complex with The Inhibitor (5r)-8-amino-3-fluoro-5,19-dimethyl-20-oxo-5,18,19,20- Tetrahydro-7,11-(azeno)pyrido(2',1':2,3)imidazo(4,5-h)(2,5,11) Benzoxadiazacyclotetradecine-14-carbonitrile
672. 4ctc: Structure of The Human Anaplastic Lymphoma Kinase in Complex with The Inhibitor 7-amino-3-cyclopropyl-12-fluoro- 1,10,16-trimethyl-16,17-dihydro-1h-8,4-(metheno)pyrazolo(4, 3-h)(2,5,11)benzoxadiazacyclotetradecin-15(10h)-one
673. 4hrl: Structural Basis for Eliciting a Cytotoxic Effect in Her2- Overexpressing Cancer Cells via Binding to The Extracellular Domain of Her2
674. 4hrm: Structural Basis for Eliciting a Cytotoxic Effect in Her2- Overexpressing Cancer Cells via Binding to The Extracellular Domain of Her2
675. 4hrn: Structural Basis for Eliciting a Cytotoxic Effect in Her2- Overexpressing Cancer Cells via Binding to The Extracellular Domain of Her2
676. 4ibm: Crystal Structure of Insulin Receptor Kinase Domain in Complex with an Inhibitor Irfin-1
677. 4iwd: Structure of Dually Phosphorylated C-met Receptor Kinase in Complex with an Mk-8033 Analog
678. 4j23: Low Resolution Crystal Structure of The FGFR2D2D3/FGF1/SR128545 Complex
679. 4k33: Crystal Strucure of Fgf Receptor 3 (fgfr3) Kinase Domain Harboring The K650E Mutation, a Gain-of-function Mutation Responsible for Thanatophoric Dysplasia Type II and Spermatocytic Seminoma
680. 4k3j: Crystal Structure of Onartuzumab Fab in Complex with Met and Hgf-beta
681. 4k94: Crystal Structure of Kit D4D5 Fragment in Complex with Anti-kit Antibody Fab19
682. 4k9e: Crystal Structure of Kit D4D5 Fragment in Complex with Anti-kit Antibodies FAB79D
683. 6q7f: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with The Nvp-bhg712 Derivative Atdl18
684. 4knb: C-met in Complex with Osi Ligand
685. 4krl: Nanobody/vhh Domain 7d12 in Complex with Domain III of The Extracellular Region of Egfr, Ph 6.0
686. 4krm: Nanobody/vhh Domain 7d12 in Complex with Domain III of The Extracellular Region of Egfr, Ph 3.5
687. 4kro: Nanobody/vhh Domain Ega1 in Complex with The Extracellular Region of Egfr
688. 4krp: Nanobody/vhh Domain 9g8 in Complex with The Extracellular Region of Egfr
689. 4li5: Egfr-k in Complex with N-[3-[[5-chloro-4-(1h-indol-3-yl)pyrimidin-2- Yl]amino]-4-methoxy-phenyl] Prop-2-enamide
690. 4liq: Structure of The Extracellular Domain of Human Csf-1 Receptor in Complex with The Fab Fragment of Rg7155
691. 4ll0: Egfr L858R/T790M in Complex with Pd168393
692. 4lqm: Egfr L858R in Complex with Pd168393
693. 4lrm: Egfr D770_N771INSNPG in Complex with Pd168393
694. 4m3q: Crystal Structure of The Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer in Complex with Inhibitor Unc1917
695. 4m4p: Crystal Structure of Epha4 Ectodomain
696. 4m4r: Epha4 Ectodomain Complex with Ephrin A5
697. 4m7e: Structural Insight into Bl-induced Activation of The Bri1-bak1 Complex
698. 4mh7: Crystal Structure of The Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer in Complex with Inhibitor Unc1896
699. 4mha: Crystal Structure of The Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer in Complex with Inhibitor Unc1817
700. 4mkc: Crystal Structure of Anaplastic Lymphoma Kinase Complexed with Ldk378
701. 4mn8: Crystal Structure of Flg22 in Complex with The Fls2 and Bak1 Ectodomains
702. 4mxc: Crystal Structure of Cmet in Complex with Novel Inhibitor
703. 4nk9: Crystal Structure of Human Fibroblast Growth Factor Receptor 1 Kinase Domain in Complex with Pyrazolaminopyrimidine 1
704. 4nka: Crystal Structure of Human Fibroblast Growth Factor Receptor 1 Kinase Domain in Complex with Pyrazolaminopyrimidine 2
705. 4nks: Crystal Structure of Human Fibroblast Growth Factor Receptor 1 Kinase Domain in Complex with Pyrazolaminopyrimidine 3
706. 4o3t: Zymogen Hgf-beta/met with Zymogen Activator Peptide Zap.14
707. 4o3u: Zymogen Hgf-beta/met with Zymogen Activator Peptide Zap2.3
708. 4oh4: Crystal Structure of Bri1 in Complex with Bki1
709. 4p2k: Structure of Ephrin Type-a Receptor 2
710. 4p4c: Human Epha3 Kinase Domain in Complex with Quinoxaline Derivatives
711. 5ya5: Crystal Structure of C-met in Complex with Novel Inhibitor
712. 4p59: Her3 Extracellular Domain in Complex with Fab Fragment of Mor09825
713. 5y9t: Crystal Structure of Egfr T790M Mutant in Complex with Naquotinib
714. 4p5q: Human Epha3 Kinase Domain in Complex with Quinoxaline Derivatives
715. 4p5z: Human Epha3 Kinase Domain in Complex with Quinoxaline Derivatives
716. 4pbv: Crystal Structure of Chicken Receptor Protein Tyrosine Phosphatase Sigma in Complex with Trkc
717. 4pbw: Crystal Structure of Chicken Receptor Protein Tyrosine Phosphatase Sigma in Complex with Trkc
718. 4pdo: Structure of Ephrin Type-a Receptor 2
719. 5y25: Egfr Kinase Domain Mutant (T790M/L858R) with Covalent Ligand Ns-062
720. 4pmm: The Structure of Trka Kinase Bound to The Inhibitor N-(3-cyclopropyl- 1-phenyl-1h-pyrazol-5-yl)-2-{4-[3-methoxy-4-(4-methyl-1h-imidazol-1- Yl)phenyl]-1h-1,2,3-triazol-1-yl}acetamide
721. 4pmp: The Structure of Trka Kinase Bound to The Inhibitor 1-cyclopropyl-1- [3-(1,3-thiazol-2-yl)benzyl]-3-[4-(trifluoromethoxy)phenyl]urea
722. 4pms: The Structure of Trka Kinase Bound to The Inhibitor 4-naphthalen-1-yl- 1-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1h-pyrrolo[3,2-c]pyridine- 2-carboxylic Acid
723. 4pmt: The Structure of Trka Kinase Bound to The Inhibitor N~4~-(4-morpholin- 4-ylphenyl)-n~6~-(pyridin-3-ylmethyl)pyrido[3,2-d]pyrimidine-4,6- Diamine
724. 5xwd: Crystal Structure of The Complex of 059-152-fv and Egfr-ecd
725. 4q5j: Crystal Structure of Semet Derivative Bri1 in Complex with Bki1
726. 5xgn: Crystal Structure of Egfr 696-1022 T790M/C797S in Complex with Go6976
727. 5xgm: Crystal Structure of Egfr 696-1022 T790M in Complex with Go6976
728. 5xfj: Crystal Structure of Ly2874455 in Complex of Fgfr4 Gatekeeper Mutation (V550M)
729. 5xff: Crystal Structure of Ly2874455 in Complex of Fgfr4 Gatekeeper Mutation (V550L)
730. 5xdl: Crystal Structure of Egfr 696-1022 L858R in Complex with Co-1686
731. 5xdk: Crystal Structure of Egfr 696-1022 T790M in Complex with Co-1686
732. 5x2k: Crystal Structure of Egfr 696-1022 T790M in Complex with Wz4003
733. 5x2f: Crystal Structure of Egfr 696-1022 T790M/V948R in Complex with Sklb(6)
734. 5x2c: Crystal Structure of Egfr 696-1022 T790M/V948R in Complex with Sklb(5)
735. 5x2a: Crystal Structure of Egfr 696-1022 T790M/V948R in Complex with Sklb(3)
736. 5x28: Crystal Structure of Egfr 696-1022 L858R in Complex with Sklb(6)
737. 5x27: Crystal Structure of Egfr 696-1022 L858R in Complex with Sklb(5)
738. 5x26: Crystal Structure of Egfr 696-1022 L858R in Complex with Sklb(3)
739. 5x02: Crystal Structure of The Flt3 Kinase Domain Bound to The Inhibitor Ff- 10101
740. 5wr7: Crystal Structure of Trk-a Complexed with a Selective Inhibitor Ch7057288
741. 5wno: Crystal Structure of C. Elegans Let-23 Kinase Domain Complexed with Amp-pnp
742. 5wb8: Crystal Structure of The Epidermal Growth Factor Receptor Extracellular Region in Complex with Epigen
743. 5wb7: Crystal Structure of The Epidermal Growth Factor Receptor Extracellular Region in Complex with Epiregulin
744. 5w59: Crystal Structure of a Monomeric Human Fgf9 in Complex with The Ectodomain of Human FGFR1C
745. 5w21: Crystal Structure of a 1:1:1 FGF23-FGFR1C-AKLOTHO Ternary Complex
746. 4qq5: Crystal Structure of Fgf Receptor (fgfr) 4 Kinase Harboring The V550L Gate-keeper Mutation in Complex with Fiin-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming Fgfr Kinase Gate-keeper Mutations
747. 4qqc: Crystal Structure of Fgf Receptor (fgfr) 4 Kinase Domain in Complex with Fiin-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming Fgfr Kinase Gate-keeper Mutations
748. 4qqj: Crystal Structure of Fgf Receptor (fgfr) 4 Kinase Domain Harboring The V550L Gate-keeper Mutation
749. 4qqt: Crystal Structure of Fgf Receptor (fgfr) 4 Tyrosine Kinase Domain
750. 4qrc: Crystal Structure of The Tyrosine Kinase Domain of Fgf Receptor 4 in Complex with Ponatinib
751. 5vz5: Crystal Structure of an Anaplastic Lymphoma Kinase-derived Neuroblastoma Tumor Antigen Bound to The Human Major Histocompatibility Complex Class I Molecule Hla-b*1501
752. 4qt8: Crystal Structure of Ron Sema-psi-ipt1 Extracellular Domains in Complex with Msp Beta-chain
753. 5vxz: High-affinity Axl Decoy Receptor
754. 4r5s: Crystal Structure of Egfr 696-1022 L858R in Complex with Fiin-3
755. 4r6v: Crystal Structure of Fgf Receptor (fgfr) 4 Kinase Harboring The V550L Gate-keeper Mutation in Complex with Fiin-3, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming Fgfr Kinase Gate-keeper Mutations
756. 4ra0: An Engineered Axl 'decoy Receptor' Effectively Silences The Gas6-axl Signaling Axis
757. 4tks: Native-sad Phasing for Human Egfr Kinase Domain.
758. 5vnd: Crystal Structure of FGFR1-Y563C (fgfr4 Surrogate) Covalently Bound to H3B-6527
759. 4trl: Structure of Ephrin Type-a Receptor 2
760. 4tye: Structural Analysis of The Human Fibroblast Growth Factor Receptor 4 Kinase
761. 4tyg: Structural Analysis of The Human Fibroblast Growth Factor Receptor 4 Kinase
762. 4tyi: Structural Analysis of The Human Fibroblast Growth Factor Receptor 4
763. 4tyj: Structural Analysis of The Human Fibroblast Growth Factor Receptor 4 Kinase
764. 4u0i: Crystal Structure of Kit in Complex with Ponatinib
765. 6iqn: Crystal Structure of Trka Kinase with Ligand
766. 4ux8: Ret Recognition of Gdnf-gfralpha1 Ligand by a Composite Binding Site Promotes Membrane-proximal Self-association
767. 4w4z: Structure of The Epha4 Lbd in Complex with Peptide
768. 4w50: Structure of The Epha4 Lbd in Complex with Peptide
769. 4wkq: 1.85 Angstrom Structure of Egfr Kinase Domain with Gefitinib
770. 4wrg: 1.9 Angstrom Structure of Egfr Kinase Domain
771. 4wun: Structure of Fgfr1 in Complex with Azd4547 (n-{3-[2-(3,5- Dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5- Dimethylpiperazin-1-yl]benzamide) at 1.65 Angstrom
772. 4rj4: Egfr Kinase (T790M/L858R) with Inhibitor Compound 6
773. 4rj5: Egfr Kinase (T790M/L858R) with Inhibitor Compound 5
774. 4rj6: Egfr Kinase (T790M/L858R) with Inhibitor Compound 4
775. 4rj7: Egfr Kinase (T790M/L858R) with Inhibitor Compound 1
776. 4rj8: Egfr Kinase (T790M/L858R) with Inhibitor Compound 8
777. 5uwd: Crystal Structure of Egfr Kinase Domain (L858R, T790M, V948R) in Complex with The Covalent Inhibitor Co-1686
778. 5utk: Crystal Structure of The Membrane Proximal Three Fibronectin Type III (fniii) Domains of Tie2 (tie2[fniiia-c])
779. 5ur1: Fgfr1 Kinase Domain Complex with Sn37333 in Reversible Binding Mode
780. 5uq0: Fgfr1 Kinase Domain Complex with Fragment 2,2-dimethyl-2,3- Dihydrobenzofuran-7-carboxamide
781. 4uxq: Fgfr4 in Complex with Ponatinib
782. 5ui0: Crystal Structure of The Tyrosine Kinase Domain of Fgf Receptor 2 Harboring an E565A/K659M Double Gain-of-function Mutation
783. 5uhn: Crystal Structure of The Tyrosine Kinase Domain of Fgf Receptor 2 Harboring a N549H/E565A Double Gain-of-function Mutation
784. 5ugx: Crystal Structure of The Tyrosine Kinase Domain of Fgf Receptor 2 Harboring a E565A/D650V Double Gain-of-function Mutation
785. 5ugl: Crystal Structure of Fgf Receptor 2 Tyrosine Kinase Domain Harboring The D650V Activating Mutation
786. 5ugc: Crystal Structure of The Egfr Kinase Domain (L858R, T790M, V948R) in Complex with a Covalent Inhibitor N-[(3r,4r)-4-fluoro-1-{6-[(3- Methoxy-1-methyl-1h-pyrazol-4-yl)amino]-9-methyl-9h-purin-2- Yl}pyrrolidin-3-yl]propanamide
787. 5ugb: Crystal Structure of The Egfr Kinase Domain in Complex with 4-(4-{[2- {[(3s)-1-acetylpyrrolidin-3-yl]amino}-9-(propan-2-yl)-9h-purin-6- Yl]amino}phenyl)-1-methylpiperazin-1-ium
788. 5uga: Crystal Structure of The Egfr Kinase Domain (L858R, T790M, V948R) in Complex with 4-(4-{[2-{[(3s)-1-acetylpyrrolidin-3-yl]amino}-9- (propan-2-yl)-9h-purin-6-yl]amino}phenyl)-1-methylpiperazin-1-ium
789. 5ug9: Crystal Structure of The Egfr Kinase Domain (L858R, T790M, V948R) in Complex with a Covalent Inhibitor N-[(3r,4r)-4-fluoro-1-{6-[(3- Methoxy-1-methyl-1h-pyrazol-4-yl)amino]-9-(propan-2-yl)-9h-purin-2- Yl}pyrrolidin-3-yl]propanamide
790. 5ug8: Crystal Structure of The Egfr Kinase Domain (L858R, T790M, V948R) in Complex with a Covalent Inhibitor N-[(3r,4r)-4-fluoro-1-{6-[(1- Methyl-1h-pyrazol-4-yl)amino]-9-(propan-2-yl)-9h-purin-2- Yl}pyrrolidin-3-yl]propanamide
791. 5uad: Met Tyrosine Kinase Inhibition Enhances The Antitumor Efficacy of an Hgf Antibody
792. 5uab: Met Tyrosine Kinase Inhibition Enhances The Antitumor Efficacy of an Hgf Antibody
793. 5u8r: Structure of The Ectodomain of The Human Type 1 Insulin-like Growth Factor Receptor
794. 5u8q: Structure of The Ectodomain of The Human Type 1 Insulin-like Growth Factor Receptor in Complex with Igf-i
795. 5u8l: Crystal Structure of Egfr Kinase Domain in Complex with a Sulfonyl Fluoride Probe Xo44
796. 5u6c: Crystal Structure of The Mer Kinase Domain in Complex with a Macrocyclic Inhibitor
797. 5u6b: Structure of The Axl Kinase Domain in Complex with a Macrocyclic Inhibitor
798. 5td2: Structure-based Optimization of 1h-imidazole-2-carboxamides as Axl Kinase Inhibitors Utilizing a Mer Mutant Surrogate
799. 5tc0: Structure-based Optimization of 1h-imidazole-2-carboxamides as Axl Kinase Inhibitors Utilizing a Mer Mutant Surrogate
800. 5t89: Crystal Structure of Vegf-a in Complex with Vegfr-1 Domains D1-6
801. 5t3q: Crystal Structure of The C-met Kinase Domain in Complex with a Pyrazolone Inhibitor
802. 5sx5: Crystal Structure of Panitumumab in Complex with Epidermal Growth Factor Receptor Domain 3 Mutant S468R.
803. 5sx4: Crystal Structure of Panitumumab in Complex with Epidermal Growth Factor Receptor Domain 3.
804. 5oyj: Crystal Structure of Vegfr-2 Domains 4-5 in Complex with Darpin D4B
805. 5ob4: Nmr Spatial Structure of Her2 Tm Domain Dimer in Dpc Micelles.
806. 5o7p: Her3 in Complex with Fab Mf3178
807. 5o4o: Her3 in Complex with Fab Mf3178
808. 5o4g: Her2 in Complex with Fab Mf3958
809. 5o4a: Human Fgf in Complex with a Covalent Inhibitor
810. 5o49: Human Fgf in Complex with a Covalent Inhibitor
811. 5nz9: Nmr Structure of an Epha2-sam Fragment
812. 5nwz: Fibroblast Growth Factor Receptor 4 Kinase Domain (449-753) in Complex with Irreversible Ligand Cga159527
813. 5nud: Fibroblast Growth Factor Receptor 4 Kinase Domain (449-753) in Complex with Irreversible Ligand Cga159527
814. 5nki: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 4b
815. 5nkh: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 3e
816. 5nkg: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 3d
817. 5nkf: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 3b
818. 5nke: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 3a
819. 5nkd: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 2i
820. 5nkc: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 2h
821. 5nkb: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 4a
822. 5nka: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 2g
823. 5nk9: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 2e
824. 5nk8: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 2f
825. 5nk7: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 2a
826. 5nk6: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 2d
827. 5nk5: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 1m
828. 5nk4: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 2c
829. 5nk3: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 1l
830. 5nk2: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 2b
831. 5nk1: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 1k
832. 5nk0: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 1j
833. 5njz: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 1g
834. 5n06: Crystal Structure of Tie1 Fibronectin-like Domain 3
835. 5myb: Homodimerization of Tie2 Fibronectin-like Domains 2 and 3 in Space Group P21
836. 5mya: Homodimerization of Tie2 Fibronectin-like Domains 1-3 in Space Group C2
837. 5my6: Crystal Structure of a Her2-nb Complex
838. 5mo9: Structure of Human Trkb Receptor Ligand Binding Domain in Complex with The Fab Frgment of Antibody Ab20
839. 5mjb: Kinase Domain of Human Ephb1, G703C Mutant, Covalently Bound to a Quinazoline-based Inhibitor
840. 5mja: Kinase Domain of Human Ephb1 Bound to a Quinazoline-based Inhibitor
841. 5lv6: N-terminal Motif Dimerization of Egfr Transmembrane Domain in Bicellar Environment
842. 5lsp: 107_a07 Fab in Complex with Fragment of The Met Receptor
843. 5lpz: Crystal Structure of The Bri1 Kinase Domain (865-1196) in Complex with Adp from Arabidopsis Thaliana
844. 5lpy: Crystal Structure of The Bri1 Kinase Domain (865-1160) in Complex with Atp from Arabidopsis Thaliana
845. 5lpw: Crystal Structure of The Apo-bri1 Kinase Domain (865-1160)
846. 5lpv: Crystal Structure of The Bri1 Kinase Domain (865-1160) in Complex with Amppnp and Mn from Arabidopsis Thaliana
847. 5lpb: Crystal Structure of The Bri1 Kinase Domain (865-1160) in Complex with Adp from Arabidopsis Thaliana
848. 5l6p: Ephb3 Kinase Domain Covalently Bound to an Irreversible Inhibitor (compound 6)
849. 5l6o: Ephb3 Kinase Domain Covalently Bound to an Irreversible Inhibitor (compound 3)
850. 5kz0: Structure of Human Anaplastic Lymphoma Kinase in Complex with 2-[(1r)- 1-{[2-amino-5-(1,3-dimethyl-1h-pyrazol-4-yl)pyridin-3-yl]oxy}ethyl]- 4-fluoro-n,n-dimethylbenzamide
851. 5kwg: Crystal Structure of Extracellular Domain of Her2 in Complex with Fcab H10-03-6
852. 5kvt: The Structure of Trka Kinase Domain Bound to The Inhibitor Entrectinib
853. 5kqv: Insulin Receptor Ectodomain Construct Comprising Domains L1,cr,l2, Fniii-1 and Alphact Peptide in Complex with Bovine Insulin and Fab 83-14 (revised Structure)
854. 5kmo: Trka Jm-kinase with 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-(2- Pyridyl)urea
855. 5kmn: Trka Jm-kinase with 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-[[2- (trifluoromethyl)phenyl]methyl]urea
856. 5kmm: Trka Jm-kinase with 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-(1- Naphthyl)urea
857. 5kml: Trka Jm-kinase with 1-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-3-[[2- (trifluoromethyl)phenyl]methyl]urea
858. 5kmk: Trka Jm-kinase with 2-fluoro-{n}-[2-(4-fluorophenyl)-6-methyl-3- Pyridyl]-4-(trifluoromethyl)benzamide
859. 5kmj: Trka Jm-kinase with {n}-(2-pyridylmethyl)-2-[2-(2-thienyl)indol-1- Yl]acetamide
860. 5kmi: Trka Jm-kinase with 1-(9{h}-fluoren-9-yl)-3-(2-methyl-4-phenyl- Pyrimidin-5-yl)urea
861. 5k5x: Crystal Structure of Human Pdgfra
862. 5k33: Crystal Structure of Extracellular Domain of Her2 in Complex with Fcab Stab19
863. 5k0x: Crystal Structure of The Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer in Complex with Inhibitor Unc2541
864. 5k0k: Crystal Structure of The Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer in Complex with Inhibitor Unc2434
865. 5jr2: Crystal Structure of The Epha4 Lbd in Complex with Apyd3 Peptide Inhibitor
866. 5jkg: The Crystal Structure of Fgfr4 Kinase Domain in Complex with Ly2874455
867. 5jfx: Crystal Structure of Trka in Complex with Pf-06273340
868. 5jfw: Crystal Structure of Trka in Complex with Pf-05247452
869. 5jfv: Crystal Structure of Trka in Complex with Pf-05206283
870. 5jfs: Crystal Structure of Trka in Complex with Pf-00593174
871. 5jeb: Crystal Structure of Egfr Tyrosine Kinase Domain with Novel Inhibitor of Active State of Her2
872. 5j9z: EGFR-T790M in Complex with Pyrazolopyrimidine Inhibitor 1a
873. 5j9y: EGFR-T790M in Complex with Pyrazolopyrimidine Inhibitor 1b
874. 5j3h: Human Insulin Receptor Domains L1-cr in Complex with Peptide S519C16 and 83-7 Fv
875. 5iyx: Crystal Structure of The Arabidopsis Receptor Kinase Haesa in Complex with The Peptide Hormone Ida and The Co-receptor Serk1
876. 5iyv: Crystal Structure of The Arabidopsis Receptor Kinase Haesa Lrr Ectdomain in Complex with The Peptide Hormone Idl1.
877. 5ixt: The Crystal Structure of The Arabidopsis Receptor Kinase Haesa Lrr Ectdomain in Complex with a N-terminal Extended Ida Peptide Hormone Ligand.
878. 5ixq: Crystal Structure of The Arabidopsis Receptor Kinase Haesa Lrr Ectdomain in Complex with The Peptide Hormone Ida.
879. 5ixo: Crystal Structure of The Arabidopsis Receptor Kinase Haesa Lrr Ectdomain (apo Form).
880. 5iui: Crystal Structure of Anaplastic Lyphoma Kinase (alk) in Complex with 4
881. 5iuh: Crystal Structure of The Anaplastic Lymphoma Kinase (alk) in Complex with 5d
882. 5iug: Crystal Structure of Anaplastic Lymphoma Kinase (alk) in Complex with 5a
883. 5imx: Anaplastic Lymphoma Kinase (alk) Catalytic Domain Complexed with Novel Inhibitor 3-sulfonylpyrazol-4-amino Pyrimidine
884. 5ia5: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Golvatinib (e7050)
885. 5ia4: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Foretinib (xl880)
886. 5ia3: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Pd173955
887. 5ia2: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Compound 66
888. 5ia1: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Mln8054
889. 5ia0: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Alisertib (mln8237)
890. 5i9z: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Danusertib (pha739358)
891. 5i9y: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Dasatinib
892. 5i9x: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Bosutinib (ski-606)
893. 5i9w: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Anp
894. 5i9v: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase with Ags
895. 5i9u: Crystal Structure of Ephrin A2 (epha2) Receptor Protein Kinase
896. 5i8a: Trka with (6~{r})-3-methylsulfanyl-6-phenyl-1-(1~{h}-pyrazol-3-yl)-6, 7-dihydro-5~{h}-thieno[3,4-c]pyridin-4-one
897. 5hzn: Structure of Nvp-aew541 in Complex with Igf-1r Kinase
898. 5hti: Crystal Structure of C-met Kinase Domain in Complex with Lxm108
899. 5hor: Crystal Structure of C-MET-M1250T in Complex with Sar125844.
900. 5hoa: Crystal Structure of C-met L1195V in Complex with Sar125844
901. 5ho6: Crystal Structure of Cmet in Complex with Cmpd.
902. 5hni: Crystal Structure of Cmet Wt with Compound 3
903. 5hlw: Crystal Structure of C-met Mutant Y1230H in Complex with Compound 14
904. 5hic: Egfr Kinase Domain Mutant "tmlr" with a Imidazopyridinyl- Aminopyrimidine Inhibitor
905. 5hib: Egfr Kinase Domain Mutant "tmlr" with a Pyrazolopyrimidine Inhibitor
906. 5hhw: Crystal Structure of Insulin Receptor Kinase Domain in Complex with Cis-(r)-7-(3-(azetidin-1-ylmethyl)cyclobutyl)-5-(3-((tetrahydro-2h- Pyran-2-yl)methoxy)phenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine.
907. 5hg9: Egfr (L858R, T790M, V948R) in Complex with 1-[(3r,4r)-3-[({2-[(1- Methyl-1h-pyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl}oxy) Methyl]-4-(trifluoromethyl)pyrrolidin-1-yl]prop-2-en-1-one
908. 5hg8: Egfr (L858R, T790M, V948R) in Complex with N-[3-({2-[(1-methyl-1h- Pyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop- 2-enamide
909. 5hg7: Egfr (L858R, T790M, V948R) in Complex with 1-{(3r,4r)-3-[5-chloro-2- (1-methyl-1h-pyrazol-4-ylamino)-7h-pyrrolo[2,3-d]pyrimidin-4- Yloxymethyl]-4-methoxy-pyrrolidin-1-yl}propenone (pf-06459988)
910. 5hg5: Egfr (L858R, T790M, V948R) in Complex with N-{3-[(2-{[4-(4- Methylpiperazin-1-yl)phenyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-4-yl) Oxy]phenyl}prop-2-enamide
911. 5hcz: Egfr Kinase Domain Mutant "tmlr" with 3-azetidinyl Azaindazole Compound 21
912. 5hcy: Egfr Kinase Domain Mutant "tmlr" with 3-carboxamide Azaindole Compound 13
913. 5hcx: Egfr Kinase Domain Mutant "tmlr" with Azabenzimidazole Compound 7
914. 5h3q: Crystal Structure of Trka Kinase with Ligand
915. 5gtz: Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39
916. 5gty: Crystal Structure of Egfr 696-1022 T790M in Complex with Lxx-6-26
917. 5grn: Crystal Structure of Pdgfra in Complex with Wq-c-159
918. 5gnk: Crystal Structure of Egfr 696-988 T790M in Complex with Lxx-6-34
919. 5gmp: Crystal Structure of Egfr 696-1022 T790M in Complex with Xtf-262
920. 5fxs: Igfr-1r Complex with a Pyrimidine Inhibitor.
921. 5fxr: Igfr-1r Complex with a Pyrimidine Inhibitor.
922. 5fxq: Igfr-1r Complex with a Pyrimidine Inhibitor.
923. 5ftq: Crystal Structure of The Alk Kinase Domain in Complex with Cmpd 17
924. 5fto: Crystal Structure of The Alk Kinase Domain in Complex with Entrectinib
925. 5fm3: Crystal Structure of Hyper-phosphorylated Ret Kinase Domain with (proximal) Juxtamembrane Segment
926. 5fm2: Crystal Structure of Hyper-phosphorylated Ret Kinase Domain with (proximal) Juxtamembrane Segment
927. 5flf: Disease Linked Mutation in Fgfr
928. 5feq: Egfr Kinase Domain in Complex with a Covalent Aminobenzimidazole
929. 5fee: Egfr Kinase Domain T790M Mutant in Complex with a Covalent Aminobenzimidazole Inhibitor.
930. 5fed: Egfr Kinase Domain in Complex with a Covalent Aminobenzimidazole Inhibitor.
931. 5fdx: Structure of Ddr1 Receptor Tyrosine Kinase in Complex with D2164 Inhibitor at 2.65 Angstroms Resolution.
932. 5fdp: Structure of Ddr1 Receptor Tyrosine Kinase in Complex with D2099 Inhibitor at 2.25 Angstroms Resolution.
933. 5eyd: Crystal Structure of C-met in Complex with Amg 337
934. 5eyc: Crystal Structure of C-met in Complex with Naphthyridinone Inhibitor 5
935. 5ew8: Fibroblast Growth Factor Receptor 1 in Complex with Jnj-4275693
936. 5ew3: Human Vascular Endothelial Growth Factor Receptor 2 (kdr) Kinase Domain in Complex with Aal993
937. 5eob: Crystal Structure of Cmet in Complex with Novel Inhibitor
938. 5em8: Egfr Kinase Domain with Pyridone Compound 13: 4-[(2-methoxyphenyl) Amino]-~{n}-[4-(4-methylpiperazin-1-yl)phenyl]-2-oxidanylidene-1~{h}- Pyridine-3-carboxamide
939. 5em7: Egfr Kinase Domain Mutant "tmlr" with Pyridone Compound 13: 4-[(2- Methoxyphenyl)amino]-~{n}-[4-(4-methylpiperazin-1-yl)phenyl]-2- Oxidanylidene-1~{h}-pyridine-3-carboxamide
940. 5em6: Egfr Kinase Domain Mutant "tmlr" with Pyridone Compound 19: 4-[(2- Azanylpyrimidin-4-yl)amino]-~{n}-[4-(4-methylpiperazin-1-yl)phenyl]- 2-oxidanylidene-1~{h}-pyridine-3-carboxamide
941. 5em5: Egfr Kinase Domain Mutant "tmlr" with Pyridone Compound 2: 4-[2-(4- Chlorophenyl)ethylamino]-~{n}-[4-(4-methylpiperazin-1-yl)phenyl]-2- Oxidanylidene-1~{h}-pyridine-3-carboxamide
942. 5ek7: Structure of The Autoinhibited Epha2 Jms-kd
943. 5eg3: Crystal Structure of The Activated Fgf Receptor 2 (fgfr2) Kinase Domain in Complex with The Csh2 Domain of Phospholipase C Gamma (plcgamma)
944. 5edr: Egfr Kinase (T790M/L858R) with Inhibitor Compound 27: ~{n}-(1~{h}- Indazol-3-yl)-7,7-dimethyl-2-(2-methylpyrazol-3-yl)-5~{h}-furo[3,4- D]pyrimidin-4-amine
945. 5edq: Egfr Kinase (T790M/L858R) with Inhibitor Compound 15: ~{n}-(7- Chloranyl-1~{h}-indazol-3-yl)-7,7-dimethyl-2-(1~{h}-pyrazol-4-yl)- 5~{h}-furo[3,4-d]pyrimidin-4-amine
946. 5edp: Egfr Kinase (T790M/L858R) Apo
947. 5e1s: The Crystal Structure of Insr Tyrosine Kinase in Complex with The Inhibitor Bi 885578
948. 5dg5: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with Altiratinib Analog Dp- 4157
949. 5d41: Egfr Kinase Domain in Complex with Mutant Selective Allosteric Inhibitor
950. 5czi: Egfr L858R Mutant in Complex with a Shc Peptide Substrate
951. 5czh: Egfr L858R Mutant in Complex with an Optimal Peptide Substrate
952. 5cus: Crystal Structure of Serbb3-fab3379 Complex
953. 5cno: Crystal Structure of The Egfr Kinase Domain Mutant V924R
954. 5cnn: Crystal Structure of The Egfr Kinase Domain Mutant I682Q
955. 5cav: Egfr Kinase Domain with Compound 41a
956. 5cau: Egfr Kinase Domain Mutant "tmlr" with Compound 41b
957. 5cas: Egfr Kinase Domain Mutant "tmlr" with Compound 41a
958. 5caq: Egfr Kinase Domain Mutant "tmlr" with Compound 33
959. 5cap: Egfr Kinase Domain Mutant "tmlr" with Compound 30
960. 5cao: Egfr Kinase Domain Mutant "tmlr" with Compound 29
961. 5can: Egfr Kinase Domain Mutant "tmlr" with Compound 27
962. 5cal: Egfr Kinase Domain Mutant "tmlr" with Compound 24
963. 5c8n: Egfr Kinase Domain Mutant "tmlr" with Compound 23
964. 5c8m: Egfr Kinase Domain Mutant "tmlr" with Compound 17
965. 5c8k: Egfr Kinase Domain Mutant "tmlr" with Compound 1
966. 5bvw: Fragment-based Discovery of Potent and Selective Ddr1/2 Inhibitors
967. 5bvo: Fragment-based Discovery of Potent and Selective Ddr1/2 Inhibitors
968. 5bvn: Fragment-based Discovery of Potent and Selective Ddr1/2 Inhibitors
969. 5bvk: Fragment-based Discovery of Potent and Selective Ddr1/2 Inhibitors
970. 4riw: Crystal Structure of an Egfr/her3 Kinase Domain Heterodimer
971. 4rix: Crystal Structure of an Egfr/her3 Kinase Domain Heterodimer Containing The Cancer-associated HER3-Q790R Mutation
972. 4riy: Crystal Structure of an Egfr/her3 Kinase Domain Heterodimer Containing The Cancer-associated HER3-E909G Mutation
973. 4x3j: Selection of Fragments for Kinase Inhibitor Design: Decoration Is Key
974. 4ckv: Crystal Structure of Vegfr-1 Domain 2 in Presence of Zn
975. 4cl7: Crystal Structure of Vegfr-1 Domain 2 in Presence of Cobalt
976. 4crp: Solution Structure of a Trkaig2 Domain Construct for Use in Drug Discovery
977. 5b7v: Human Fgfr1 Kinase in Complex with Ch5183284
978. 5aoq: Structural Basis of Neurohormone Perception by The Receptor Tyrosine Kinase Torso
979. 5amn: The Discovery of 2-substituted Phenol Quinazolines as Potent and Selective Ret Kinase Inhibitors
980. 5abd: Crystal Structure of Vegfr-1 Domain 2 in Presence of Cu
981. 5aac: Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib
982. 5aab: Structure of C1156Y,L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib
983. 5aaa: Structure of L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib
984. 5aa9: Structure of L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with Pf-06463922 ((10r)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo- 10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) Benzoxadiazacyclotetradecine-3-carbonitrile).
985. 5aa8: Structure of C1156Y,L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with Pf-06463922 ((10r)-7-amino-12- Fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2h- 8,4-(metheno)pyrazolo(4,3-h)(2,5,11) Benzoxadiazacyclotetradecine-3-carbonitrile).
986. 5a9u: Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with Pf-06463922 ((10r)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo- 10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) Benzoxadiazacyclotetradecine-3-carbonitrile).
987. 4tt7: Crystal Structure of Human Alk with a Covalent Modification
988. 4zse: Crystal Structure of Egfr 696-1022 T790M/V948R, Crystal Form II
989. 4zsa: Crystal Structure of Fgfr1 Kinase Domain in Complex with 7n
990. 4zjv: Crystal Structure of Egfr Kinase Domain in Complex with Mitogen- Inducible Gene 6 Protein
991. 4uwy: Fgfr1 Apo Structure
992. 4zau: Azd9291 Complex with Wild Type Egfr
993. 4uxl: Structure of Human Ros1 Kinase Domain in Complex with Pf-06463922
994. 4z64: The Plant Peptide Hormone Receptor Complex in Arabidopsis
995. 4z55: Anaplastic Lymphoma Kinase Catalytic Domain Complexed with Pyrazolopyrimidine Derivative of Ldk378
996. 4xmo: Crystal Structure of C-met in Complex with (r)-5-(8-fluoro-3-(1- Fluoro-1-(3-methoxyquinolin-6-yl)ethyl)-[1,2,4]triazolo[4,3- A]pyridin-6-yl)-3-methylisoxazole
997. 4xyf: Crystal Structure of C-met in Complex with (s)-5-(8-fluoro-3-(1-(3-(2- Methoxyethoxy)quinolin-6-yl)ethyl)-[1,2,4]triazolo[4,3-a]pyridin-6- Yl)-3-methylisoxazole
998. 4pgz: Structural Basis of Kit Activation by Oncogenic Mutations in The Extracellular Region Reveals a Zipper-like Mechanism for Ligand- Dependent or Oncogenic Receptor Tyrosine Kinase Activation
999. 4r1v: Identification and Optimization of Pyridazinones as Potent and Selective C-met Kinase Inhibitors
1000. 4r1y: Identification and Optimization of Pyridazinones as Potent and Selective C-met Kinase Inhibitor
1001. 5am6: Native Fgfr1 with an Inhibitor
1002. 5am7: Fgfr1 Mutant with an Inhibitor
1003. 3wsq: Structure of Her2 with an Fab
1004. 4xlv: Crystal Structure of The Activated Insulin Receptor Tyrosine Kinase Dimer
1005. 4xcu: Crystal Structure of Fgfr4 with an Irreversible Inhibitor
1006. 4yps: (r)-2-phenylpyrrolidine Substitute Imidazopyridazines: a New Class of Potent and Selective Pan-trk Inhibitors
1007. 4yne: (r)-2-phenylpyrrolidine Substitute Imidazopyridazines: a New Class of Potent and Selective Pan-trk Inhibitors
1008. 4ymj: (r)-2-phenylpyrrolidine Substitute Imidazopyridazines: a New Class of Potent and Selective Pan-trk Inhibitors
1009. 3wlw: Molecular Architecture of The Erbb2 Extracellular Domain Homodimer
1010. 3wzd: Kdr in Complex with Ligand Lenvatinib
1011. 3wze: Kdr in Complex with Ligand Sorafenib
1012. 4d2r: Human Igf in Complex with a DYRK1B Inhibitor
1013. 4rt7: Crystal Structure of Flt3 with a Small Molecule Inhibitor
1014. 4rwi: Crystal Structure of V561M Fgfr1 Gatekeeper Mutation (C488A, C584S, V561M), Apo
1015. 4rwj: Crystal Structure of Fgfr1 (C488A, C584S) in Complex with Azd4547 (n- {3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5- Dimethylpiperazin-1-yl]benzamide)
1016. 4rwk: Crystal Structure of V561M Fgfr1 Gatekeeper Mutation (C488A, C584S, V561M) in Complex with N-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h- Pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide (azd4547)
1017. 4rwl: Crystal Structure of Fgfr1 (C488A, C584C) in Complex with 6-(7-((1- Aminocyclopropyl) Methoxy)-6-methoxyquinolin-4-yloxy)-n-methyl-1- Naphthamide (e3810)
1018. 4twn: Human Epha3 Kinase Domain in Complex with Birb796
1019. 4two: Human Epha3 Kinase Domain in Complex with Compound 164
1020. 4xuf: Crystal Structure of The Flt3 Kinase Domain Bound to The Inhibitor Quizartinib (ac220)
1021. 2n5s: Spatial Structure of Egfr Transmembrane and Juxtamembrane Domains in Dpc Micelles
1022. 2n90: Trka Transmembrane Domain Nmr Structure in Dpc Micelles
1023. 4r3p: Crystal Structures of Egfr in Complex with Mig6
1024. 4r3r: Crystal Structures of Egfr in Complex with Mig6
1025. 4r7h: Crystal Structure of Fms Kinase Domain with a Small Molecular Inhibitor, Plx3397
1026. 4r7i: Crystal Structure of Fms Kinase Domain with a Small Molecular Inhibitor, Gleevec
1027. 4uv7: The Complex Structure of Extracellular Domain of Egfr and GC1118A
1028. 4uwb: Fibroblast Growth Factor Receptor 1 Kinase in Complex with Jk-p5
1029. 4uwc: Fibroblast Growth Factor Receptor 1 Kinase in Complex with Jk-p3
1030. 4wd5: Crystal Structure of Egfr 696-1022 T790M in Complex with Ql-x138
1031. 4wrl: Structure of The Human Csf-1:csf-1r Complex
1032. 4wrm: Structure of The Human Csf-1:csf-1r Complex
1033. 4wv1: Crystal Structure of The Fgfr2 D2 Domain in Complex with Fab 2b.1.3
1034. 4xss: Insulin-like Growth Factor I in Complex with Site 1 of a Hybrid Insulin Receptor / Type 1 Insulin-like Growth Factor Receptor
1035. 4xst: Structure of The Endoglycosidase-h Treated L1-cr Domains of The Human Insulin Receptor in Complex with Residues 697-719 of The Human Insulin Receptor (a-isoform)
1036. 7aml: Ret/gdnf/gfra1 Extracellular Complex Cryo-em Structure
1037. 7b7n: Human Herpesvirus-8 Gh/gl in Complex with Epha2
1038. 7jy4: Halk in Complex with ((1s,2s)-1-(2,4-difluorophenyl)-2-(2-(3-methyl- 1h-pyrazol-5-yl)-4-(trifluoromethyl)phenoxy)cyclopropyl)methanamine
1039. 7jyr: Halk in Complex with 1-[(1r,2r)-1-(2,4-difluorophenyl)-2-[2-(5-methyl- 1h-pyrazol-3-yl)-4-(trifluoromethyl)phenoxy]cyclopropyl]methanamine
1040. 7jys: Halk in Complex with 3-(3-chlorophenyl)-5-methyl-1h-pyrazole
1041. 7jyt: Halk in Complex with 3-(3-methyl-1h-pyrazol-5-yl)pyridine
1042. 7amk: Zebrafish Ret Cadherin like Domains 1 to 4.
1043. 7dhl: Crystal Structure of Fgfr3 in Complex with Pyrimidine Derivative
1044. 7kja: Crystal Structure of The Epha2 Intracellular Kd-sam Domains
1045. 7kjb: Crystal Structure of The Epha2 S897E/S901E Mutant Intracellular Kd-sam Domains
1046. 7kjc: Crystal Structure of The Epha2 S901E Mutant Intracellular Kd-sam Domains
1047. 6wxj: CSF1R Signaling Is a Regulator of Pathogenesis in Progressive Ms
1048. 7kia: Crystal Structure of Fgfr2 Kinase Domain Gatekeeper Mutant V564F in Complex with Covalent Compound 19
1049. 7kie: Crystal Structure of Fgfr2 Kinase Domain Gatekeeper Mutant V564F in Complex with Covalent Compound 3
1050. 7avx: Mertk Kinase Domain in Complex with Nps-1034
1051. 7avy: Mertk Kinase Domain in Complex with Quinazoline-based Inhbitor
1052. 7avz: Mertk Kinase Domain in Complex with a Bisaminopyrimidine Inhibitor
1053. 7aw0: Mertk Kinase Domain in Complex with Purine Inhibitor
1054. 7aw1: Mertk Kinase Domain in Complex with a Type 2 Inhibitor
1055. 7aw2: Mertk Kinase Domain with Type 1.5 Inhibitor from a Dna-encoded Library
1056. 7aw3: Mertk Kinase Domain with Type 1 Inhibitor from a Dna-encoded Library
1057. 7aw4: Mertk Kinase Domain with Type 3 Inhibitor from a Dna-encoded Library
1058. 7bcm: The Ddr1 Kinase Domain Bound to Sr302
1059. 7be6: Structure of Ddr1 Receptor Tyrosine Kinase in Complex with Inhibitor Sr159
1060. 7kpl: Crystal Structure of Hephb1 in Apo Form
1061. 7kpm: Crystal Structure of Hephb1 Bound with Adp
1062. 7lbf: Cryoem Structure of The Hcmv Trimer Ghglgo in Complex with Human Platelet-derived Growth Factor Receptor Alpha and Neutralizing Fabs 13h11 and Msl-109
1063. 6wa2: Crystal Structure of EGFR(T790M/V948R) in Complex with Ln3753
1064. 6wak: A Crystal Structure of EGFR(T790M/V948R) in Complex with Ln3754
1065. 7aem: Studies towards a Reversible Egfr C797S Triple Mutant Inhibitor Series
1066. 7btt: A X-ray Cocrystal Structure of Xmu-mp-5 Bound to The Alk Kinase Domain
1067. 7d85: Crystal Structure of Anti-erbb3 Fab Isu104 in Complex with Human Erbb3 Extracellular Domain 3
1068. 7bw7: Cryo-em Structure for The Ectodomain of The Full-length Human Insulin Receptor in Complex with 1 Insulin.
1069. 7bw8: Cryo-em Structure for The Insulin Binding Region in The Ectodomain of The Full-length Human Insulin Receptor in Complex with 1 Insulin
1070. 7bwa: Cryo-em Structure for The Ectodomain of The Full-length Human Insulin Receptor in Complex with 2 Insulin
1071. 7dtz: Fgfr4 Complex with a Covalent Inhibitor
1072. 6wxn: EGFR(T790M/V948R) in Complex with Ln3844
1073. 7oam: Kinase Domain of Mertk in Complex with Compound 8
1074. 7aei: Studies towards a Reversible Egfr C797S Triple Mutant Inhibitor Series
1075. 7mo7: Cryo-em Structure of 2:2 C-met/hgf Holo-complex
1076. 7mo8: Cryo-em Structure of 1:1 C-met I/hgf I Complex after Focused 3d Refinement of Holo-complex
1077. 7mo9: Cryo-em Map of The C-met Ii/hgf I/hgf II (k4 and Sph) Sub-complex
1078. 7moa: Cryo-em Structure of The C-met Ii/hgf I Complex Bound with Hgf II in a Rigid Conformation
1079. 7mob: Cryo-em Structure of 2:2 C-met/nk1 Complex
1080. 6xl4: EGFR(T790M/V948R) in Complex with Azd9291 and Ddc4002
1081. 7eec: Crystal Structure of Epha7 Mutant G656R
1082. 7eed: Crystal Structure of Epha7 Mutant D751H
1083. 7eef: Crystal Structure of Epha7 Mutant G656E
1084. 7khg: Crystal Structure of Kit Kinase Domain with a Small Molecule Inhibitor, Plx3397
1085. 7ofv: Nmr-guided Design of Potent and Selective Epha4 Agonistic Ligands
1086. 7jxh: Her2 in Complex with Jbj-08-178-01
1087. 7jxi: Egfr Kinase (T790M/V948R) in Complex with Pf-06747775
1088. 7jxk: Egfr Kinase (T790M/V948R) in Complex with Pf-06747775 and Jbj-04-125- 02
1089. 7jxl: Egfr Kinase (T790M/V948R) in Complex with Az5104
1090. 7jxm: Egfr Kinase (T790M/V948R) in Complex with Osimertinib and Eai045
1091. 7jxp: Egfr Kinase (T790M/V948R) in Complex with Osimertinib and Jbj-04-125- 02
1092. 7jxq: Egfr Kinase (T790M/V948R) in Complex with Allosteric Inhibitor Jbj-09- 063
1093. 7jxw: Egfr Kinase (T790M/V948R) in Complex with Osimertinib and Jbj-09-063
1094. 7k1h: Egfr L858R/V948R in Complex with Osimertinib and Allosteric Inhibitor Jbj-09-063
1095. 7k1i: Egfr Kinase (L858R/V948R) in Complex with Allosteric Inhibitor Jbj-09- 063
1096. 7ols: Mertk Kinase Domain with Type 1.5 Inhibitor Containing a Di-methyl Pyrazole Group
1097. 7olv: Mertk Kinase Domain with Type 1.5 Inhibitor Containing a Di-methyl, Cyano Pyrazole Group
1098. 7olx: Mertk Kinase Domain with Type 1.5 Inhibitor Containing a Tri-methyl Pyrazole Group
1099. 7lgs: Structure of EGFR_D770_N771INSNPG/V948R in Complex with Covalent Inhibitor Osimertinib.
1100. 7m5z: Crystal Structure of The Mertk Kinase Domain in Complex with Inhibitor Mips15692
1101. 7dxl: Fragment-based Lead Discovery of Indazole-based Compounds as Axl Kinase Inhibitors
1102. 7kd6: Insulin Receptor L1-cr plus Alphact Fragment in Co-complex with Fv 83- 7 and Single-chain Insulin Sci-b
1103. 7me4: Structure of The Extracellular Wnt-binding Module in Drosophila Ror2/nrk
1104. 7vkm: Crystal Structure of Trka (G595R) Kinase Domain
1105. 7vkn: Crystal Structure of Trka (G595R) Kinase with Repotrectinib
1106. 7vko: Crystal Structure of Trka Kinase with Repotrectinib
1107. 7oxb: Crystal Structure of Egfr Double Mutant (T790M/L858R) in Complex with Compound 6.
1108. 7mn5: Structure of The HER2/HER3/NRG1B Heterodimer Extracellular Domain
1109. 7mn6: Structure of The Her2 S310F/HER3/NRG1B Heterodimer Extracellular Domain
1110. 7nwz: Alk:alkal2 Complex
1111. 7nx0: Extracellular Tg and Egf-like Domains of Alk
1112. 7nx1: Tg Domain of Ltk
1113. 7nx3: Crystal Structure of Alk in Complex with Fab324
1114. 7nx4: Crystal Structure of The Tg and Egf-like Domains of Alk
1115. 7s7k: Crystal Structure of The Ephb2 Extracellular Domain
1116. 7e72: Crystal Structure of Tie2-agonistic Antibody in Complex with Human Tie2 Fn2-3
1117. 7mn8: Structure of The HER2/HER3/NRG1B Heterodimer Extracellular Domain Bound to Trastuzumab Fab
1118. 7len: Crystal Structure of The Epidermal Growth Factor Receptor Extracellular Region with R84K Mutation in Complex with Epiregulin Crystallized with Trehalose
1119. 7lfr: Crystal Structure of The Epidermal Growth Factor Receptor Extracellular Region with R84K Mutation in Complex with Epiregulin Crystallized with Spermine
1120. 7lfs: Crystal Structure of The Epidermal Growth Factor Receptor Extracellular Region with A265V Mutation in Complex with Epiregulin
1121. 7bhe: Darpin_d5/her3 Domain 4 Complex, Monoclinic Crystals
1122. 7bhf: Darpin_d5/her3 Domain 4 Complex, Orthorhombic Crystals
1123. 7lir: Structure of The Invertebrate Alk Grd
1124. 7lrz: Structure of The Human Alk Grd
1125. 7ls0: Structure of The Human Alk Grd Bound to Aug
1126. 7mfc: Crystal Structure of CSF1R in Complex with Vimseltinib
1127. 7mzy: Anaplastic Lymphoma Kinase (alk) Extracellular Fragment of Ligand Binding Region 673-986
1128. 7n00: Anaplastic Lymphoma Kinase (alk) Extracellular Fragment of Ligand Binding Region 648-1025 in Complex with Aug-alpha
1129. 7mzw: Anaplastic Lymphoma Kinase (alk) Extracellular Ligand Binding Region 673-1025
1130. 7sz7: Cryo-em Structure of The Extracellular Module of The Full-length Egfr Bound to Tgf-alpha. "tips-juxtaposed" Conformation
1131. 7syd: Cryo-em Structure of The Extracellular Module of The Full-length Egfr Bound to Egf "tips-juxtaposed" Conformation
1132. 7sye: Cryo-em Structure of The Extracellular Module of The Full-length Egfr Bound to Egf. "tips-separated" Conformation
1133. 7sz0: Cryo-em Structure of The Extracellular Module of The Full-length Egfr L834R Bound to Egf. "tips-juxtaposed" Conformation
1134. 7sz1: Cryo-em Structure of The Extracellular Module of The Full-length Egfr L834R Bound to Egf. "tips-separated" Conformation
1135. 7sz5: Cryo-em Structure of The Extracellular Module of The Full-length Egfr Bound to Tgf-alpha "tips-separated" Conformation