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enzyme (lysozyme)

 
Enzymes
  Enzyme classes:
  EC 1: Oxidoreductases
  EC 2: Transferases
    EC 2.1
    EC 2.2
    EC 2.3
    EC 2.4
    EC 2.5
    EC 2.6
    EC 2.7
      EC 2.7.1
      EC 2.7.2
      EC 2.7.3
      EC 2.7.4
      EC 2.7.5
      EC 2.7.6
      EC 2.7.7
      EC 2.7.8
      EC 2.7.9
      EC 2.7.10
        EC 2.7.10.1
        EC 2.7.10.2
      EC 2.7.11
      EC 2.7.12
      EC 2.7.13
      EC 2.7.14
    EC 2.8
    EC 2.9
  EC 3: Hydrolases
  EC 4: Lyases
  EC 5: Isomerases
  EC 6: Ligases
  General information:
  Catalytic mechanism
  Enzyme kinetics
  Inhibitors
  Enzymes in industry

EC 2.7.10.1 - ATP:[protein] - L- tyrosine O- phosphotransferase (receptor- type) (receptor protein- tyrosine kinase)



3D structures of EC 2.7.10.1 - receptor protein-tyrosine kinase in Protein Data Bank

updated: 29 May 2015, 1:12

In total: 544 PDB structures of EC 2.7.10.1 - receptor protein-tyrosine kinase:
  1. 1igr: Type 1 Insulin-like Growth Factor Receptor (domains 1-3)
  2. 3pls: Ron in Complex with Ligand Amp-pnp
  3. 3nw7: Crystal Structure of Insulin-like Growth Factor 1 Receptor (igf-1r-wt) Complex with a Carbon-linked Proline Isostere Inhibitor (34)
  4. 3nw6: Crystal Structure of Insulin-like Growth Factor 1 Receptor (igf-1r-wt) Complex with a Carbon-linked Proline Isostere Inhibitor (11a)
  5. 3nw5: Crystal Structure of Insulin-like Growth Factor 1 Receptor (igf-1r-wt) Complex with a Carbon-linked Proline Isostere Inhibitor (11b)
  6. 3njp: The Extracellular and Transmembrane Domain Interfaces in Epidermal Growth Factor Receptor Signaling
  7. 1m6b: Structure of The Her3 (erbb3) Extracellular Domain
  8. 3n85: Crystallographic Trimer of Her2 Extracellular Regions in Complex with Tryptophan-rich Antibody Fragment
  9. 3mzw: Her2 Extracelluar Region with Affinity Matured 3-helix Affibody Zher2:342
  10. 3mx0: Crystal Structure of Epha2 Ectodomain in Complex with Ephrin-a5
  11. 3mjg: The Structure of a Platelet Derived Growth Factor Receptor Complex
  12. 3mbw: Crystal Structure of The Human Ephrin A2 Lbd and Crd Domains in Complex with Ephrin A1
  13. 3lw0: Igf-1rk in Complex with Ligand MSC1609119A-1
  14. 3lvp: Crystal Structure of Bisphosphorylated Igf1-r Kinase Domain (2p) in Complex with a Bis-azaindole Inhibitor
  15. 3lq8: Structure of The Kinase Domain of C-met Bound to Xl880 (gsk1363089)
  16. 3loh: Structure of The Insulin Receptor Ectodomain, including Ct Peptide
  17. 3lmg: Crystal Structure of The Erbb3 Kinase Domain in Complex with Amp-pnp
  18. 3lct: Crystal Structure of The Anaplastic Lymphoma Kinase Catalytic Domain
  19. 3lcs: Crystal Structure of The Anaplastic Lymphoma Kinase Catalytic Domain
  20. 3lco: Inhibitor Bound to a Dfg-out Structure of The Kinase Domain of Csf-1r
  21. 3lcd: Inhibitor Bound to a Dfg-in Structure of The Kinase Domain of Csf-1r
  22. 3l9p: Crystal Structure of The Anaplastic Lymphoma Kinase Catalytic Domain
  23. 3l8v: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with a Biarylamine Based Inhibitor
  24. 3l8p: Crystal Structure of Cytoplasmic Kinase Domain of Tie2 Complexed with Inhibitor Cep11207
  25. 3ky2: Crystal Structure of Fibroblast Growth Factor Receptor 1 Kinase Domain
  26. 3kxx: Structure of The Mutant Fibroblast Growth Factor Receptor 1
  27. 3kvq: Crystal Structure of Vegfr2 Extracellular Domain D7
  28. 3kul: Kinase Domain of Human Ephrin Type-a Receptor 8 (epha8)
  29. 3krl: Cfms Tyrosine Kinase in Complex with 5-cyano-furan-2-carboxylic Acid [4-(4-methyl-piperazin-1-yl)-2-piperidin-1-yl-phenyl]-amide
  30. 3krj: Cfms Tyrosine Kinase in Complex with 4-cyano-1h-imidazole-2-carboxylic Acid (2-cyclohex-1-enyl-4-piperidin-4-yl-phenyl)-amide
  31. 3kka: Co-crystal Structure of The Sam Domains of Epha1 and Epha2
  32. 3kex: Crystal Structure of The Catalytically Inactive Kinase Domain of The Human Epidermal Growth Factor Receptor 3 (her3)
  33. 3js2: Crystal Structure of Minimal Kinase Domain of Fibroblast Growth Factor Receptor 1 in Complex with 5-(2-thienyl) Nicotinic Acid
  34. 3ika: Crystal Structure of Egfr 696-1022 T790M Mutant Covalently Binding to Wz4002
  35. 3i5n: Crystal Structure of C-met with Triazolopyridazine Inhibitor 13
  36. 3hpn: Ligand Recognition by A-class Eph Receptors: Crystal Structures of The Epha2 Ligand-binding Domain and The Epha2/ephrin-a1 Complex
  37. 3hng: Crystal Structure of Vegfr1 in Complex with N-(4- Chlorophenyl)-2-((pyridin-4-ylmethyl)amino)benzamide
  38. 3hkl: Crystal Structure of The Frizzled-like Cysteine-rich Domain of Musk
  39. 3hil: Sam Domain of Human Ephrin Type-a Receptor 1 (epha1)
  40. 3hei: Ligand Recognition by A-class Eph Receptors: Crystal Structures of The Epha2 Ligand-binding Domain and The Epha2/ephrin-a1 Complex
  41. 3h8m: Sam Domain of Human Ephrin Type-a Receptor 7 (epha7)
  42. 3h3b: Crystal Structure of The Single-chain Fv (scfv) Fragment of an Anti- Erbb2 Antibody Cha21 in Complex with Residues 1-192 of Erbb2 Extracellular Domain
  43. 3gxu: Crystal Structure of Eph Receptor and Ephrin Complex
  44. 3gt8: Crystal Structure of The Inactive Egfr Kinase Domain in Complex with Amp-pnp
  45. 3gql: Crystal Structure of Activated Receptor Tyrosine Kinase in Complex with Substrates
  46. 3gqi: Crystal Structure of Activated Receptor Tyrosine Kinase in Complex with Substrates
  47. 3gop: Crystal Structure of The Egf Receptor Juxtamembrane and Kinase Domains
  48. 3g0f: Kit Kinase Domain Mutant D816H in Complex with Sunitinib
  49. 3g0e: Kit Kinase Domain in Complex with Sunitinib
  50. 3fy2: Human Epha3 Kinase and Juxtamembrane Region Bound to Substrate Kqwdnyefiw
  51. 3fxx: Human Epha3 Kinase and Juxtamembrane Region Bound to Substrate Kqwdnye[ptyr]iw
  52. 3fl7: Crystal Structure of The Human Ephrin A2 Ectodomain
  53. 3f82: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with N- (4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4- Ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3- Carboxamide
  54. 3f66: Human C-met Kinase in Complex with Quinoxaline Inhibitor
  55. 3f5p: Complex Structure of Insulin-like Growth Factor Receptor and 3-cyanoquinoline Inhibitor
  56. 3ewh: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Pyridyl-pyrimidine Benzimidazole Inhibitor
  57. 3euu: Crystal Structure of The Fgfr2 D2 Domain
  58. 3etp: The Crystal Structure of The Ligand-binding Domain of The Ephb2 Receptor at 2.0 a Resolution
  59. 3eta: Kinase Domain of Insulin Receptor Complexed with a Pyrrolo Pyridine Inhibitor
  60. 3ekn: Insulin Receptor Kinase Complexed with an Inhibitor
  61. 3ekk: Insulin Receptor Kinase Complexed with an Inhibitor
  62. 3ejj: Structure of M-csf Bound to The First Three Domains of Fms
  63. 3efl: Crystal Structure of The Vegfr2 Kinase Domain in Complex with Motesanib
  64. 3efk: Structure of C-met with Pyrimidone Inhibitor 50
  65. 3efj: Structure of C-met with Pyrimidone Inhibitor 7
  66. 3dzq: Human Epha3 Kinase Domain in Complex with Inhibitor Awl-ii- 38.3
  67. 3dtw: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Benzisoxazole Inhibitor
  68. 3dpk: Cfms Tyrosine Kinase in Complex with a Pyridopyrimidinone Inhibitor
  69. 3dko: Complex between The Kinase Domain of Human Ephrin Type-a Receptor 7 (epha7) and Inhibitor Alw-ii-49-7
  70. 3dar: Crystal Structure of D2 Domain from Human Fgfr2
  71. 3d94: Crystal Structure of The Insulin-like Growth Factor-1 Receptor Kinase in Complex with Pqip
  72. 3czu: Crystal Structure of The Human Ephrin A2- Ephrin A1 Complex
  73. 3cu1: Crystal Structure of 2:2:2 FGFR2D2:FGF1:SOS Complex
  74. 3ctj: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with a Aminopyridine Based Inhibitor
  75. 3cth: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with a Aminopyridine Based Inhibitor
  76. 3cpc: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Pyridone Inhibitor
  77. 3cpb: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Bisamide Inhibitor
  78. 3cp9: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Pyridone Inhibitor
  79. 3cly: Crystal Structure of Fgf Receptor 2 (fgfr2) Kinase Domains Trapped in Trans-phosphorylation Reaction
  80. 3ckh: Crystal Structure of Eph A4 Receptor
  81. 3cjg: Crystal Structure of Vegfr2 in Complex with a 3,4,5- Trimethoxy Aniline Containing Pyrimidine
  82. 3cjf: Crystal Structure of Vegfr2 in Complex with a 3,4,5- Trimethoxy Aniline Containing Pyrimidine
  83. 3ce3: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with a Pyrrolopyridinepyridone Based Inhibitor
  84. 3cd8: X-ray Structure of C-met with Triazolopyridazine Inhibitor.
  85. 3ccn: X-ray Structure of C-met with Triazolopyridazine Inhibitor.
  86. 3caf: Crystal Structure of Hfgfr2 D2 Domain
  87. 3c8x: Crystal Structure of The Ligand Binding Domain of Human Ephrin A2 (epha2) Receptor Protein Kinase
  88. 3c7q: Structure of Vegfr2 Kinase Domain in Complex with Bibf1120
  89. 3c4f: Fgfr Tyrosine Kinase Domain in Complex with 3-(3- Methoxybenzyl)-7-azaindole
  90. 3c1x: Crystal Structure of The Tyrosine Kinase Domain of The Hepatocyte Growth Factor Receptor C-met in Complex with a Pyrrolotriazine Based Inhibitor
  91. 3c09: Crystal Structure The Fab Fragment of Matuzumab (fab72000) in Complex with Domain III of The Extracellular Region of Egfr
  92. 3bu6: Crystal Structure of The Insulin Receptor Kinase in Complex with Irs2 Krlb Phosphopeptide
  93. 3bu5: Crystal Structure of The Insulin Receptor Kinase in Complex with Irs2 Krlb Peptide and Atp
  94. 3bu3: Crystal Structure of The Insulin Receptor Kinase in Complex with Irs2 Krlb Peptide
  95. 3brb: Crystal Structure of Catalytic Domain of The Proto-oncogene Tyrosine- Protein Kinase Mer in Complex with Adp
  96. 3bpr: Crystal Structure of Catalytic Domain of The Proto-oncogene Tyrosine- Protein Kinase Mer in Complex with Inhibitor C52
  97. 3bel: X-ray Structure of Egfr in Complex with Oxime Inhibitor
  98. 3bea: Cfms Tyrosine Kinase (tie2 Kid) in Complex with a Pyrimidinopyridone Inhibitor
  99. 3be2: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Benzamide Inhibitor
  100. 3be1: Dual Specific Bh1 Fab in Complex with The Extracellular Domain of Her2/erbb-2
  101. 3bce: Crystal Structure of The Erbb4 Kinase
  102. 3bbw: Crystal Structure of The Erbb4 Kinase in Its Inactive Conformation
  103. 3bbt: Crystal Structure of The Erbb4 Kinase in Complex with Lapatinib
  104. 3b8r: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Naphthamide Inhibitor
  105. 3b8q: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Naphthamide Inhibitor
  106. 3b2v: Crystal Structure of The Extracellular Region of The Epidermal Growth Factor Receptor in Complex with The Fab Fragment of Imc-11f8
  107. 3b2u: Crystal Structure of Isolated Domain III of The Extracellular Region of The Epidermal Growth Factor Receptor in Complex with The Fab Fragment of Imc-11f8
  108. 3b2t: Structure of Phosphotransferase
  109. 3a4p: Human C-met Kinase Domain Complexed with 6- Benzyloxyquinoline Inhibitor
  110. 2zm3: Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor
  111. 2z8c: Phosphorylated Insulin Receptor Tyrosine Kinase in Complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2- Yl]amino}phenyl)acetic Acid
  112. 2z4f: Solution Structure of The Discoidin Domain of Ddr2
  113. 2ys5: Solution Structure of The Complex of The Ptb Domain of Snt-2 and 19- Residue Peptide (aa 1571-1589) of Halk
  114. 2xp2: Structure of The Human Anaplastic Lymphoma Kinase in Complex with Crizotinib (pf-02341066)
  115. 2xba: Structure of Human Anaplastic Lymphoma Kinase in Complex with Pha-e429
  116. 2xb7: Structure of Human Anaplastic Lymphoma Kinase in Complex with Nvp- Tae684
  117. 2xac: Structural Insights into The Binding of Vegf-b by Vegfr-1d2: Recognition and Specificity
  118. 2x9f: Ephb4 Kinase Domain Inhibitor Complex
  119. 2x2u: First Two Cadherin-like Domains from Human Ret
  120. 2x2m: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain with Inhibitor
  121. 2x2l: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain with Inhibitor
  122. 2x2k: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain with Inhibitor
  123. 2x11: Crystal Structure of The Complete Epha2 Ectodomain in Complex with Ephrin A5 Receptor Binding Domain
  124. 2x10: Crystal Structure of The Complete Epha2 Ectodomain
  125. 2wqb: Structure of The Tie2 Kinase Domain in Complex with a Thiazolopyrimidine Inhibitor
  126. 2wo3: Crystal Structure of The Epha4-ephrina2 Complex
  127. 2wo2: Crystal Structure of The Epha4-ephrinb2 Complex
  128. 2wo1: Crystal Structure of The Epha4 Ligand Binding Domain
  129. 2wkm: X-ray Structure of Pha-00665752 Bound to The Kinase Domain of C-met
  130. 2wgj: X-ray Structure of Pf-02341066 Bound to The Kinase Domain of C-met
  131. 1yy9: Structure of The Extracellular Domain of The Epidermal Growth Factor Receptor in Complex with The Fab Fragment of Cetuximab/erbitux/imc-c225
  132. 2wd1: Human C-met Kinase in Complex with Azaindole Inhibitor
  133. 2vx1: Ephb4 Kinase Domain Inhibitor Complex
  134. 2vx0: Ephb4 Kinase Domain Inhibitor Complex
  135. 2vwz: Ephb4 Kinase Domain Inhibitor Complex
  136. 2vwy: Ephb4 Kinase Domain Inhibitor Complex
  137. 2vwx: Ephb4 Kinase Domain Inhibitor Complex
  138. 2vww: Ephb4 Kinase Domain Inhibitor Complex
  139. 2vwv: Ephb4 Kinase Domain Inhibitor Complex
  140. 2vwu: Ephb4 Kinase Domain Inhibitor Complex
  141. 2rl5: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a 2,3-dihydro-1,4-benzoxazine Inhibitor
  142. 2rgp: Structure of Egfr in Complex with Hydrazone, a Potent Dual Inhibitor
  143. 2rfs: X-ray Structure of Su11274 Bound to C-met
  144. 2rfn: X-ray Structure of C-met with Inhibitor.
  145. 2rfe: Crystal Structure of The Complex between The Egfr Kinase Domain and a Mig6 Peptide
  146. 2rfd: Crystal Structure of The Complex between The Egfr Kinase Domain and a Mig6 Peptide
  147. 2rf9: Crystal Structure of The Complex between The Egfr Kinase Domain and a Mig6 Peptide
  148. 2rei: Kinase Domain of Human Ephrin Type-a Receptor 7 (epha7)
  149. 2r4b: Erbb4 Kinase Domain Complexed with a Thienopyrimidine Inhibitor
  150. 2r2p: Kinase Domain of Human Ephrin Type-a Receptor 5 (epha5)
  151. 2qu6: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Benzoxazole Inhibitor
  152. 2qu5: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Benzimidazole Inhibitor
  153. 2qoq: Human Epha3 Kinase and Juxtamembrane Region, Base, Amp-pnp Bound Structure
  154. 2qoo: Human Epha3 Kinase and Juxtamembrane Region, Y596F:Y602F:Y742F Triple Mutant
  155. 2qon: Human Epha3 Kinase and Juxtamembrane Region, Y596F:Y602F:Y742A Triple Mutant
  156. 2qol: Human Epha3 Kinase and Juxtamembrane Region, Y596:Y602:S768G Triple Mutant
  157. 2qok: Human Epha3 Kinase and Juxtamembrane Region, Y596F:Y602F:S768A Triple Mutant
  158. 2qoi: Human Epha3 Kinase and Juxtamembrane Region, Y596F:Y602F Double Mutant
  159. 2qof: Human Epha3 Kinase and Juxtamembrane Region, Y596F Mutant
  160. 2qod: Human Epha3 Kinase and Juxtamembrane Region, Y602F Mutant
  161. 2qoc: Human Epha3 Kinase Domain, Phosphorylated, Amp-pnp Bound Structure
  162. 2qob: Human Epha3 Kinase Domain, Base Structure
  163. 2qo9: Human Epha3 Kinase and Juxtamembrane Region, Phosphorylated, Amp-pnp Bound
  164. 2qo7: Human Epha3 Kinase and Juxtamembrane Region, Dephosphorylated, Amp-pnp Bound
  165. 2qo2: Human Epha3 Kinase and Juxtamembrane Region, Dephosphorylated, Apo Structure
  166. 2qkq: Structure of The Sam Domain of Human Ephrin Type-b Receptor 4
  167. 2ckn: Nmr Structure of The First Ig Module of Mouse Fgfr1
  168. 2qbx: Ephb2/snew Antagonistic Peptide Complex
  169. 2q0b: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic E565A Mutation Responsible for Pfeiffer Syndrome
  170. 2pzr: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome
  171. 2pzp: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic K526E Mutation Responsible for Crouzon Syndrome
  172. 2pz5: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic N549T Mutation Responsible for Pfeiffer Syndrome
  173. 2py3: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic E565G Mutation Responsible for Pfeiffer Syndrome
  174. 2pwl: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic N549H Mutation Responsible for Crouzon Syndrome.
  175. 2pvy: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome.
  176. 2pvf: Crystal Structure of Tyrosine Phosphorylated Activated Fgf Receptor 2 (fgfr2) Kinase Domain in Complex with Atp Analog and Substrate Peptide
  177. 2psq: Crystal Structure of Unphosphorylated Unactivated Wild Type Fgf Receptor 2 (fgfr2) Kinase Domain
  178. 2p4i: Evolution of a Highly Selective and Potent 2-(pyridin-2-yl)- 1,3,5-triazine Tie-2 Kinase Inhibitor
  179. 2p2i: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Nicotinamide Inhibitor
  180. 2p2h: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Pyridinyl-triazine Inhibitor
  181. 2p0c: Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer
  182. 2osc: Synthesis, Structural Analysis, and Sar Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors
  183. 2oo8: Synthesis, Structural Analysis, and Sar Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors
  184. 2oh4: Crystal Structure of Vegfr2 with a Benzimidazole-urea Inhibitor
  185. 2ogv: Crystal Structure of The Autoinhibited Human C-fms Kinase Domain
  186. 2dtg: Insulin Receptor (ir) Ectodomain in Complex with Fab's
  187. 2o26: Structure of a Class III Rtk Signaling Assembly
  188. 2e7h: Solution Structure of The Second Fn3 Domain from Human Ephrin Type-b Receptor 4
  189. 2e8n: Solution Structure of The C-terminal Sam-domain of Ephaa2: Ephrin Type-a Receptor 2 Precursor (ec 2.7.10.1)
  190. 2e9w: Crystal Structure of The Extracellular Domain of Kit in Complex with Stem Cell Factor (scf)
  191. 2eao: Solution Structure of The C-terminal Sam-domain of Mouse Ephrin Type-b Receptor 1 Precursor (ec 2.7.1.112)
  192. 2eb2: Crystal Structure of Mutated Egfr Kinase Domain (G719S)
  193. 2eb3: Crystal Structure of Mutated Egfr Kinase Domain (L858R) in Complex with Amppnp
  194. 2ec8: Crystal Structure of The Exctracellular Domain of The Receptor Tyrosine Kinase, Kit
  195. 2l4k: Water Refined Solution Structure of The Human Grb7-sh2 Domain in Complex with The 10 Amino Acid Peptide Py1139
  196. 2gs2: Crystal Structure of The Active Egfr Kinase Domain
  197. 2gs6: Crystal Structure of The Active Egfr Kinase Domain in Complex with an Atp Analog-peptide Conjugate
  198. 2gs7: Crystal Structure of The Inactive Egfr Kinase Domain in Complex with Amp-pnp
  199. 2gsf: The Human Epha3 Receptor Tyrosine Kinase and Juxtamembrane Region
  200. 2gy5: Tie2 Ligand-binding Domain Crystal Structure
  201. 2gy7: Angiopoietin-2/tie2 Complex Crystal Structure
  202. 2hen: Crystal Structure of The Ephb2 Receptor Kinase Domain in Complex with Adp
  203. 2hle: Structural and Biophysical Characterization of The Ephb4- Ephrinb2 Protein Protein Interaction and Receptor Specificity.
  204. 2i0v: C-fms Tyrosine Kinase in Complex with a Quinolone Inhibitor
  205. 2i0y: Cfms Tyrosine Kinase (fgf Kid) in Complex with an Arylamide Inhibitor
  206. 2i1m: Cfms Tyrosine Kinase (tie2 Kid) in Complex with an Arylamide Inhibitor
  207. 2iep: Crystal Structure of Immunoglobulin-like Domains 1 and 2 of The Receptor Tyrosine Kinase Musk
  208. 2ifg: Structure of The Extracellular Segment of Human Trka in Complex with Nerve Growth Factor
  209. 2itn: Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Amp-pnp
  210. 2ito: Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Iressa
  211. 2itp: Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Aee788
  212. 2itq: Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Afn941
  213. 2itt: Crystal Structure of Egfr Kinase Domain L858R Mutation in Complex with Aee788
  214. 2itu: Crystal Structure of Egfr Kinase Domain L858R Mutation in Complex with Afn941
  215. 2itv: Crystal Structure of Egfr Kinase Domain L858R Mutation in Complex with Amp-pnp
  216. 2itw: Crystal Structure of Egfr Kinase Domain in Complex with Afn941
  217. 2itx: Crystal Structure of Egfr Kinase Domain in Complex with Amp- Pnp
  218. 2ity: Crystal Structure of Egfr Kinase Domain in Complex with Iressa
  219. 2itz: Crystal Structure of Egfr Kinase Domain L858R Mutation in Complex with Iressa
  220. 2ivs: Crystal Structure of Non-phosphorylated Ret Tyrosine Kinase Domain
  221. 2ivt: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain
  222. 2ivu: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with The Inhibitor Zd6474
  223. 2ivv: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with The Inhibitor Pp1
  224. 2j5e: Crystal Structure of Egfr Kinase Domain in Complex with an Irreversible Inhibitor 13-jab
  225. 2j5f: Crystal Structure of Egfr Kinase Domain in Complex with an Irreversible Inhibitor 34-jab
  226. 2j6m: Crystal Structure of Egfr Kinase Domain in Complex with Aee788
  227. 2jiv: Crystal Structure of Egfr Kinase Domain T790M Mutation in Compex with Hki-272
  228. 2jwa: Erbb2 Transmembrane Segment Dimer Spatial Structure
  229. 2k1l: Nmr Structures of Dimeric Transmembrane Domain of The Receptor Tyrosine Kinase Epha1 in Lipid Bicelles at Ph 6.3
  230. 2k9y: Epha2 Dimeric Structure in The Lipidic Bicelle at Ph 5.0
  231. 2kgt: Solution Structure of Sh3 Domain of Ptk6
  232. 2ks1: Heterodimeric Association of Transmembrane Domains of Erbb1 and Erbb2 Receptors Enabling Kinase Activation
  233. 3nru: Ligand Binding Domain of Epha7
  234. 3lzb: Egfr Kinase Domain Complexed with an Imidazo[2,1-b]thiazole Inhibitor
  235. 3p1i: Ligand Binding Domain of Human Ephrin Type-b Receptor 3
  236. 3q6u: Structure of The Apo Met Receptor Kinase in The Dually-phosphorylated, Activated State
  237. 3q6w: Structure of Dually-phosphorylated Met Receptor Kinase in Complex with an Mk-2461 Analog with Specificity for The Activated Receptor
  238. 2xir: Crystal Structure of The Vegfr2 Kinase Domain in Complex with Pf-00337210 (n,2-dimethyl-6-(7-(2-morpholinoethoxy) Quinolin-4-yloxy)benzofuran-3-carboxamide)
  239. 3poz: Egfr Kinase Domain Complexed with Tak-285
  240. 3pp0: Crystal Structure of The Kinase Domain of Human Her2 (erbb2).
  241. 3qqu: Cocrystal Structure of Unphosphorylated Igf with Pyrimidine 8
  242. 3qs7: Crystal Structure of a Human Flt3 Ligand-receptor Ternary Complex
  243. 3qs9: Crystal Structure of a Human Flt3 Ligand-receptor Ternary Complex
  244. 3rhk: Crystal Structure of The Catalytic Domain of C-met Kinase in Complex with Arq 197
  245. 2yfx: Structure of L1196M Mutant Anaplastic Lymphoma Kinase in Complex with Crizotinib
  246. 3o23: Human Unphosphorylated Igf1-r Kinase Domain in Complex with an Hydantoin Inhibitor
  247. 3rhx: Crystal Structure of The Catalytic Domain of Fgfr1 Kinase in Complex with Arq 069
  248. 3ri1: Crystal Structure of The Catalytic Domain of Fgfr2 Kinase in Complex with Arq 069
  249. 2l9u: Spatial Structure of Dimeric Erbb3 Transmembrane Domain
  250. 2yhv: Structure of L1196M Mutant Anaplastic Lymphoma Kinase
  251. 3aox: X-ray Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with Ch5424802
  252. 2xvd: Ephb4 Kinase Domain Inhibitor Complex
  253. 3qti: C-met Kinase in Complex with Nvp-bvu972
  254. 3rgx: Structural Insight into Brassinosteroid Perception by Bri1
  255. 3rgz: Structural Insight into Brassinosteroid Perception by Bri1
  256. 3riz: Crystal Structure of The Plant Steroid Receptor Bri1 Ectodomain
  257. 3rj0: Plant Steroid Receptor Bri1 Ectodomain in Complex with Brassinolide
  258. 3s35: Structural Basis for The Function of Two Anti-vegf Receptor Antibodies
  259. 3s36: Structural Basis for The Function of Two Anti-vegf Receptor Antibodies
  260. 3s37: Structural Basis for The Function of Two Anti-vegf Receptor Antibodies
  261. 3oj2: Crystal Structure of Fgf1 Complexed with The Ectodomain of FGFR2B Harboring The A172F Pfeiffer Syndrome Mutation
  262. 3ojm: Crystal Structure of Fgf1 Complexed with The Ectodomain of FGFR2B Harboring P253R Apert Mutation
  263. 3skj: Structural and Functional Characterization of an Agonistic Anti-human Epha2 Monoclonal Antibody
  264. 3zxz: X-ray Structure of Pf-04217903 Bound to The Kinase Domain of C-met
  265. 2l2t: Solution Nmr Structure of The Erbb4 Dimeric Membrane Domain
  266. 3zze: Crystal Structure of C-met Kinase Domain in Complex with N'- ((3z)-4-chloro-7-methyl-2-oxo-1,2-dihydro-3h-indol-3- Ylidene)-2-(4-hydroxyphenyl)propanohydrazide
  267. 3zzw: Crystal Structure of The Kinase Domain of Ror2
  268. 3p0y: Anti-egfr/her3 Fab Dl11 in Complex with Domain III of Egfr Extracellular Region
  269. 3p11: Anti-egfr/her3 Fab Dl11 in Complex with Domains I-iii of The Her3 Extracellular Region
  270. 2y6m: Crystal Structure of Epha4 Kinase Domain
  271. 2y6o: Crystal Structure of Epha4 Kinase Domain in Complex with Dasatinib.
  272. 3u2p: Crystal Structure of N-terminal Three Extracellular Domains of Erbb4/her4
  273. 3vhe: Crystal Structure of Human Vegfr2 Kinase Domain with a Novel Pyrrolopyrimidine Inhibitor.
  274. 3rcd: Her2 Kinase Domain Complexed with Tak-285
  275. 2xyu: Crystal Structure of Epha4 Kinase Domain in Complex with Vuf 12058
  276. 3qup: Inhibitor Bound Structure of The Kinase Domain of The Murine Receptor Tyrosine Kinase Tyro3 (sky)
  277. 3ojv: Crystal Structure of Fgf1 Complexed with The Ectodomain of FGFR1C Exhibiting an Ordered Ligand Specificity-determining Betac'-betae Loop
  278. 3tl8: The Avrptob-bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains in a Single Type III Effector
  279. 3v2a: Vegfr-2/vegf-a Complex Structure
  280. 3v6b: Vegfr-2/vegf-e Complex Structure
  281. 3qwq: Crystal Structure of The Extracellular Domain of The Epidermal Growth Factor Receptor in Complex with an Adnectin
  282. 3r7o: Structure of Dually Phosphorylated C-met in Complex with Mk-2461
  283. 3v5q: Discovery of a Selective Trk Inhibitor with Efficacy in Rodent Cancer Tumor Models
  284. 4dce: Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with a Piperidine-carboxamide Inhibitor
  285. 3u6h: Crystal Structure of C-met in Complex with Pyrazolone Inhibitor 26
  286. 3u6i: Crystal Structure of C-met in Complex with Pyrazolone Inhibitor 58a
  287. 3u6j: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Pyrazolone Inhibitor
  288. 3ug1: Crystal Structure of The Mutated Egfr Kinase Domain (G719S/T790M) in The Apo Form
  289. 3ug2: Crystal Structure of The Mutated Egfr Kinase Domain (G719S/T790M) in Complex with Gefitinib
  290. 3vjn: Crystal Structure of The Mutated Egfr Kinase Domain (G719S/T790M) in Complex with Amppnp.
  291. 3vjo: Crystal Structure of The Wild-type Egfr Kinase Domain in Complex with Amppnp.
  292. 3vnt: Crystal Structure of The Kinase Domain of Human Vegfr2 with a [1, 3]thiazolo[5,4-b]pyridine Derivative
  293. 4dkd: Crystal Structure of Human Interleukin-34 Bound to Human Csf-1r
  294. 4ag4: Crystal Structure of a Ddr1-fab Complex
  295. 2lcx: Spatial Structure of The Erbb4 Dimeric Tm Domain
  296. 3uim: Structural Basis for The Impact of Phosphorylation on Plant Receptor- like Kinase Bak1 Activation
  297. 2l6w: Pdgfr Beta-tm
  298. 4deg: Crystal Structure of C-met in Complex with Triazolopyridazine Inhibitor 2
  299. 4deh: Crystal Structure of C-met in Complex with Triazolopyridinone Inhibitor 3
  300. 4dei: Crystal Structure of C-met in Complex with Triazolopyridinone Inhibitor 24
  301. 4exp: Structure of Mouse Interleukin-34 in Complex with Mouse Fms
  302. 2yjr: Structure of F1174L Mutant Anaplastic Lymphoma Kinase
  303. 2yjs: Structure of C1156Y Mutant Anaplastic Lymphoma Kinase
  304. 3tt0: Co-structure of Fibroblast Growth Factor Receptor 1 Kinase Domain with 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1- Yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (bgj398)
  305. 4f63: Crystal Structure of Human Fibroblast Growth Factor Receptor 1 Kinase Domain in Complex with Compound 1
  306. 4f64: Crystal Structure of Human Fibroblast Growth Factor Receptor 1 Kinase Domain in Complex with Compound 6
  307. 4f65: Crystal Structure of Human Fibroblast Growth Factor Receptor 1 Kinase Domain in Complex with Compound 8
  308. 3tcp: Crystal Structure of The Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer in Complex with Inhibitor Unc569
  309. 4fob: Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with Acyliminobenzimidazole Inhibitor 1
  310. 4foc: Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with Acyliminobenzimidazole Inhibitor 2
  311. 4fod: Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with Acyliminobenzimidazole Inhibitor 36
  312. 4aw5: Complex of The Ephb4 Kinase Domain with an Oxindole Inhibitor
  313. 4fww: Crystal Structure of The Sema-psi Extracellular Domains of Human Ron Receptor Tyrosine Kinase
  314. 3vid: Crystal Structure of Human Vegfr2 Kinase Domain with Compound A.
  315. 4aoj: Human Trka in Complex with The Inhibitor Az-23
  316. 4asz: Crystal Structure of Apo Trkb Kinase Domain
  317. 4at3: Crystal Structure of Trkb Kinase Domain in Complex with CPD5N
  318. 4at4: Crystal Structure of Trkb Kinase Domain in Complex with Ex429
  319. 4at5: Crystal Structure of Trkb Kinase Domain in Complex with Gw2580
  320. 3u7u: Crystal Structure of Extracellular Region of Human Epidermal Growth Factor Receptor 4 in Complex with Neuregulin-1 Beta
  321. 3vhk: Crystal Structure of The Vegfr2 Kinase Domain in Complex with a Back Pocket Binder
  322. 4ag8: Crystal Structure of The Vegfr2 Kinase Domain in Complex with Axitinib (ag-013736) (n-methyl-2-(3-((e)-2-pyridin-2- Yl-vinyl)-1h-indazol-6-ylsulfanyl)-benzamide)
  323. 4agc: Crystal Structure of Vegfr2 (juxtamembrane and Kinase Domains) in Complex with Axitinib (ag-013736) (n-methyl-2-( 3-((e)-2-pyridin-2-yl-vinyl)-1h-indazol-6-ylsulfanyl)- Benzamide)
  324. 4agd: Crystal Structure of Vegfr2 (juxtamembrane and Kinase Domains) in Complex with Sunitinib (su11248) (n-2- Diethylaminoethyl)-5-((z)-(5-fluoro-2-oxo-1h-indol-3- Ylidene)methyl)-2,4-dimethyl-1h-pyrrole-3-carboxamide)
  325. 4aoi: Crystal Structure of C-met Kinase Domain in Complex with 4-( 3-((1h- Pyrrolo(2,3-b)pyridin-3-yl)methyl)-(1,2,4)triazolo( 4,3-b)(1,2,4) Triazin-6-yl)benzonitrile
  326. 4ap7: Crystal Structure of C-met Kinase Domain in Complex with 4-( (6-(4- Fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin-3-yl)methyl) Phenol
  327. 4asd: Crystal Structure of Vegfr2 (juxtamembrane and Kinase Domains) in Complex with Sorafenib (bay 43-9006)
  328. 4ase: Crystal Structure of Vegfr2 (juxtamembrane and Kinase Domains) in Complex with Tivozanib (av-951)
  329. 4f0i: Crystal Structure of Apo Trka
  330. 4fnw: Crystal Structure of The Apo F1174L Anaplastic Lymphoma Kinase Catalytic Domain
  331. 4fnx: Crystal Structure of The Apo R1275Q Anaplastic Lymphoma Kinase Catalytic Domain
  332. 4fny: Crystal Structure of The R1275Q Anaplastic Lymphoma Kinase Catalytic Domain in Complex with a Benzoxazole Inhibitor
  333. 4fnz: Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with Piperidine-carboxamide Inhibitor 2
  334. 4g5j: Crystal Structure of Egfr Kinase in Complex with Bibw2992
  335. 4g5p: Crystal Structure of Egfr Kinase T790M in Complex with Bibw2992
  336. 4gt4: Structure of Unliganded, Inactive Ror2 Kinase Domain
  337. 4gt5: Crystal Structure of The Inactive Trka Kinase Domain
  338. 4gg5: Crystal Structure of Cmet in Complex with Novel Inhibitor
  339. 4gg7: Crystal Structure of Cmet in Complex with Novel Inhibitor
  340. 3u9u: Crystal Structure of Extracellular Domain of Human Erbb4/her4 in Complex with The Fab Fragment of Mab1479
  341. 4g2f: Human Epha3 Kinase Domain in Complex with Compound 7
  342. 3ulz: Crystal Structure of Apo Bak1
  343. 4hjo: Crystal Structure of The Inactive Egfr Tyrosine Kinase Domain with Erlotinib
  344. 4hwu: Crystal Structure of The Ig-c2 Type 1 Domain from Mouse Fibroblast Growth Factor Receptor 2 (fgfr2) [nysgrc-005912]
  345. 3w11: Insulin Receptor Ectodomain Construct Comprising Domains L1-cr in Complex with Human Insulin, Alpha-ct Peptide(704-719) and Fab 83-7
  346. 3w12: Insulin Receptor Ectodomain Construct Comprising Domains L1-cr in Complex with High-affinity Insulin Analogue [d-pro-b26]-dti-nh2, Alpha-ct Peptide(704-719) and Fab 83-7
  347. 3w13: Insulin Receptor Ectodomain Construct Comprising Domains L1-cr in Complex with High-affinity Insulin Analogue [d-pro-b26]-dti-nh2, Alphact Peptide(693-719) and Fab 83-7
  348. 3w14: Insulin Receptor Ectodomain Construct Comprising Domains L1,cr,l2, Fniii-1 and Alphact Peptide in Complex with Bovine Insulin and Fab 83-14
  349. 3w2o: Egfr Kinase Domain T790M/L858R Mutant with Tak-285
  350. 3w2p: Egfr Kinase Domain T790M/L858R Mutant with Compound 2
  351. 3w2q: Egfr Kinase Domain T790M/L858R Mutant with Hki-272
  352. 3w2r: Egfr Kinase Domain T790M/L858R Mutant with Compound 4
  353. 3w2s: Egfr Kinase Domain with Compound4
  354. 4bb4: Ephb4 Kinase Domain Inhibitor Complex
  355. 4gk2: Human Epha3 Kinase Domain in Complex with Ligand 66
  356. 4gk3: Human Epha3 Kinase Domain in Complex with Ligand 87
  357. 4gk4: Human Epha3 Kinase Domain in Complex with Ligand 90
  358. 4i1z: Crystal Structure of The Monomeric (V948R) Form of The Gefitinib/erlotinib Resistant Egfr Kinase Domain L858R+T790M
  359. 4i20: Crystal Structure of Monomeric (V948R) Primary Oncogenic Mutant L858R Egfr Kinase Domain
  360. 4i21: Crystal Structure of L858R + T790M Egfr Kinase Domain in Complex with Mig6 Peptide
  361. 4i22: Structure of The Monomeric (V948R)GEFITINIB/ERLOTINIB Resistant Double Mutant (L858R+T790M) Egfr Kinase Domain Co-crystallized with Gefitinib
  362. 4i23: Crystal Structure of The Wild-type Egfr Kinase Domain in Complex with Dacomitinib (soaked)
  363. 4i24: Structure of T790M Egfr Kinase Domain Co-crystallized with Dacomitinib
  364. 3vo3: Crystal Structure of The Kinase Domain of Human Vegfr2 with Imidazo[1, 2-b]pyridazine Derivative
  365. 3vrp: Crystal Structure of The Tyrosine Kinase Binding Domain of Cbl-c in Complex with Phospho-egfr Peptide
  366. 3vrr: Crystal Structure of The Tyrosine Kinase Binding Domain of Cbl-c (pl Mutant) in Complex with Phospho-egfr Peptide
  367. 3w32: Egfr Kinase Domain Complexed with Compound 20a
  368. 3w33: Egfr Kinase Domain Complexed with Compound 19b
  369. 4anl: Structure of G1269A Mutant Anaplastic Lymphoma Kinase
  370. 4anq: Structure of G1269A Mutant Anaplastic Lymphoma Kinase in Complex with Crizotinib
  371. 4ans: Structure of L1196M,G1269A Double Mutant Anaplastic Lymphoma Kinase in Complex with Crizotinib
  372. 4eev: Crystal Structure of C-met in Complex with Ly2801653
  373. 4feq: Inhibitor Bound Structure of The Kinase Domain of The Murine Receptor Tyrosine Kinase Tyro3 (sky)
  374. 4ff8: Inhibitor Bound Structure of The Kinase Domain of The Murine Receptor Tyrosine Kinase Tyro3 (sky)
  375. 4hvs: Crystal Structure of Kit Kinase Domain with a Small Molecule Inhibitor, Plx647
  376. 4hw7: Crystal Structure of Fms Kinase Domain with a Small Molecular Inhibitor, Plx647-ome
  377. 3zos: Structure of The Ddr1 Kinase Domain in Complex with Ponatinib
  378. 3zbf: Structure of Human Ros1 Kinase Domain in Complex with Crizotinib
  379. 4bkj: Crystal Structure of The Human Ddr1 Kinase Domain in Complex with Imatinib
  380. 4et7: Crystal Structure of Eph Receptor 5
  381. 4jq7: Crystal Structure of Egfr Kinase Domain in Complex with Compound 2a
  382. 4jq8: Crystal Structure of Egfr Kinase Domain in Complex with Compound 4b
  383. 4jr3: Crystal Structure of Egfr Kinase Domain in Complex with Compound 3g
  384. 4jrv: Crystal Structure of Egfr Kinase Domain in Complex with Compound 4c
  385. 4bk4: Crystal Structure of The Human Epha4 Ectodomain
  386. 4bk5: Crystal Structure of The Human Epha4 Ectodomain in Complex with Human Ephrin A5 (amine-methylated Sample)
  387. 4bka: Crystal Structure of The Human Epha4 Ectodomain in Complex with Human Ephrin A5
  388. 4bkf: Crystal Structure of The Human Epha4 Ectodomain in Complex with Human Ephrinb3
  389. 4joa: Crystal Structure of Human Anaplastic Lymphoma Kinase in Complex with 7-azaindole Based Inhibitor
  390. 4leo: Crystal Structure of Anti-her3 Fab Rg7116 in Complex with The Extracellular Domains of Human Her3 (erbb3)
  391. 4bsj: Crystal Structure of Vegfr-3 Extracellular Domains D4-5
  392. 4bsk: Crystal Structure of Vegf-c in Complex with Vegfr-3 Domains D1-2
  393. 4j95: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome in Space Group C2.
  394. 4j96: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic Gain-of-function K659M Mutation Identified in Cervical Cancer.
  395. 4j97: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Pathogenic Gain-of-function K659E Mutation Identified in Endometrial Cancer.
  396. 4j98: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Gain-of-function K659Q Mutation.
  397. 4j99: Crystal Strucure of Fgf Receptor 2 (fgfr2) Kinase Domain Harboring The Gain-of-function K659T Mutation.
  398. 2lzl: FGFR3TM
  399. 2m0b: Homodimeric Transmembrane Domain of The Human Receptor Tyrosine Kinase Erbb1 (egfr, Her1) in Micelles
  400. 2m59: Spatial Structure of Dimeric Vegfr2 Membrane Domain in Dpc Micelles
  401. 2met: Nmr Spatial Structure of The Trimeric Mutant Tm Domain of Vegfr2 Receptor.
  402. 2meu: Nmr Spatial Structure of Mutant Dimeric Tm Domain of Vegfr2 Receptor
  403. 2mfq: Nmr Solution Structures of FRS2A Ptb Domain with Neurotrophin Receptor Trkb
  404. 2mfr: Solution Structure of The Transmembrane Domain of The Insulin Receptor in Micelles
  405. 2yn8: Ephb4 Kinase Domain Inhibitor Complex
  406. 3vw8: Crystal Structure of Human C-met Kinase Domain with Its Inhibitor
  407. 3wj6: Human Fgfr1 Kinase in Complex with Ch5183284
  408. 3zbx: X-ray Structure of C-met Kinase in Complex with Inhibitor 6- ((6-(4-fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin- 3-yl)methyl)quinoline.
  409. 3zc5: X-ray Structure of C-met Kinase in Complex with Inhibitor ( S)-6-(1-(6-(1-methyl-1h-pyrazol-4-yl)-(1,2,4)triazolo(4,3- B)pyridazin-3-yl)ethyl)quinoline.
  410. 3zcl: X-ray Structure of C-met Kinase in Complex with Inhibitor ( S)-3-(1-(1h-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-n-isopropyl-( 1,2,4)triazolo(4,3-b)pyridazin-6-amine
  411. 3zew: Crystal Structure of Ephb4 in Complex with Staurosporine
  412. 3zfm: Crystal Structure of Ephb2
  413. 3zfx: Crystal Structure of Ephb1
  414. 3zfy: Crystal Structure of Ephb3
  415. 4ccb: Structure of The Human Anaplastic Lymphoma Kinase in Complex with 3-((r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl) Phenyl)ethoxy)-5-(5-methyl-1h-pyrazol-4-yl)pyridin-2-amine
  416. 4ccu: Structure of The Human Anaplastic Lymphoma Kinase in Complex with 2-(5-(6-amino-5-((r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl) Phenyl)ethoxy)pyridin-3-yl)-4-methylthiazol-2-yl)propan-2-ol
  417. 4cd0: Structure of L1196M Mutant Human Anaplastic Lymphoma Kinase in Complex with 2-(5-(6-amino-5-((r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl) Phenyl)ethoxy)pyridin-3-yl)-4-methylthiazol-2-yl)propane-1,2-diol
  418. 4cki: Crystal Structure of Oncogenic Ret Tyrosine Kinase M918T Bound to Adenosine
  419. 4ckj: Crystal Structure of Ret Tyrosine Kinase Domain Bound to Adenosine
  420. 4ckr: Crystal Structure of The Human Ddr1 Kinase Domain in Complex with Ddr1-in-1
  421. 4cli: Structure of The Human Anaplastic Lymphoma Kinase in Complex with Pf-06463922 ((10r)-7-amino-12-fluoro-2,10,16-trimethyl-15 -oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo(4,3-h) (2,5,11)benzoxadiazacyclotetradecine-3-carbonitrile).
  422. 4clj: Structure of L1196M Mutant Human Anaplastic Lymphoma Kinase in Complex with Pf-06463922 ((10r)-7-amino-12-fluoro-2,10, 16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno) Pyrazolo(4,3-h)(2,5,11)benzoxadiazacyclotetradecine-3- Carbonitrile).
  423. 4cmo: Structure of The Human Anaplastic Lymphoma Kinase in Complex with The Inhibitor 2-((1r)-1-((3-amino-6-(2- Methoxypyridin- -yl)pyrazin-2-yl)oxy)ethyl)-4-fluoro-n-methylbenzamide
  424. 4cmt: Structure of The Human Anaplastic Lymphoma Kinase in Complex with The Inhibitor 3-((1r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl) Phenyl)ethoxy)-5-(3-(methylsulfonyl)phenyl)pyridin-2-amine
  425. 4cmu: Structure of The Human Anaplastic Lymphoma Kinase in Complex with The Inhibitor (10r)-7-amino-12-fluoro-1,3,10, 16-tetramethyl-16,17-dihydro-1h-8,4-(metheno)pyrazolo(4,3- H)(2,5,11)benzoxadiazacyclotetradecin-15(10h)-one
  426. 4cnh: Structure of The Human Anaplastic Lymphoma Kinase in Complex with The Inhibitor 3-((1r)-1-(5-fluoro-2- Methoxyphenyl)ethoxy)-5-(1-methyl-1h-1,2,3-triazol-5-yl) Pyridin-2-amine
  427. 4ctb: Structure of The Human Anaplastic Lymphoma Kinase in Complex with The Inhibitor (5r)-8-amino-3-fluoro-5,19-dimethyl-20-oxo-5,18,19,20- Tetrahydro-7,11-(azeno)pyrido(2',1':2,3)imidazo(4,5-h)(2,5,11) Benzoxadiazacyclotetradecine-14-carbonitrile
  428. 4ctc: Structure of The Human Anaplastic Lymphoma Kinase in Complex with The Inhibitor 7-amino-3-cyclopropyl-12-fluoro- 1,10,16-trimethyl-16,17-dihydro-1h-8,4-(metheno)pyrazolo(4, 3-h)(2,5,11)benzoxadiazacyclotetradecin-15(10h)-one
  429. 4hrl: Structural Basis for Eliciting a Cytotoxic Effect in Her2- Overexpressing Cancer Cells via Binding to The Extracellular Domain of Her2
  430. 4hrm: Structural Basis for Eliciting a Cytotoxic Effect in Her2- Overexpressing Cancer Cells via Binding to The Extracellular Domain of Her2
  431. 4hrn: Structural Basis for Eliciting a Cytotoxic Effect in Her2- Overexpressing Cancer Cells via Binding to The Extracellular Domain of Her2
  432. 4ibm: Crystal Structure of Insulin Receptor Kinase Domain in Complex with an Inhibitor Irfin-1
  433. 4iwd: Structure of Dually Phosphorylated C-met Receptor Kinase in Complex with an Mk-8033 Analog
  434. 4j23: Low Resolution Crystal Structure of The FGFR2D2D3/FGF1/SR128545 Complex
  435. 4k33: Crystal Strucure of Fgf Receptor 3 (fgfr3) Kinase Domain Harboring The K650E Mutation, a Gain-of-function Mutation Responsible for Thanatophoric Dysplasia Type II and Spermatocytic Seminoma
  436. 4k3j: Crystal Structure of Onartuzumab Fab in Complex with Met and Hgf-beta
  437. 4k94: Crystal Structure of Kit D4D5 Fragment in Complex with Anti-kit Antibody Fab19
  438. 4k9e: Crystal Structure of Kit D4D5 Fragment in Complex with Anti-kit Antibodies FAB79D
  439. 4knb: C-met in Complex with Osi Ligand
  440. 4krl: Nanobody/vhh Domain 7d12 in Complex with Domain III of The Extracellular Region of Egfr, Ph 6.0
  441. 4krm: Nanobody/vhh Domain 7d12 in Complex with Domain III of The Extracellular Region of Egfr, Ph 3.5
  442. 4kro: Nanobody/vhh Domain Ega1 in Complex with The Extracellular Region of Egfr
  443. 4krp: Nanobody/vhh Domain 9g8 in Complex with The Extracellular Region of Egfr
  444. 4li5: Egfr-k in Complex with N-[3-[[5-chloro-4-(1h-indol-3-yl)pyrimidin-2- Yl]amino]-4-methoxy-phenyl] Prop-2-enamide
  445. 4liq: Structure of The Extracellular Domain of Human Csf-1 Receptor in Complex with The Fab Fragment of Rg7155
  446. 4ll0: Egfr L858R/T790M in Complex with Pd168393
  447. 4lqm: Egfr L858R in Complex with Pd168393
  448. 4lrm: Egfr D770_N771INSNPG in Complex with Pd168393
  449. 4m3q: Crystal Structure of The Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer in Complex with Inhibitor Unc1917
  450. 4m4p: Crystal Structure of Epha4 Ectodomain
  451. 4m4r: Epha4 Ectodomain Complex with Ephrin A5
  452. 4m7e: Structural Insight into Bl-induced Activation of The Bri1-bak1 Complex
  453. 4mh7: Crystal Structure of The Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer in Complex with Inhibitor Unc1896
  454. 4mha: Crystal Structure of The Catalytic Domain of The Proto-oncogene Tyrosine-protein Kinase Mer in Complex with Inhibitor Unc1817
  455. 4mkc: Crystal Structure of Anaplastic Lymphoma Kinase Complexed with Ldk378
  456. 4mn8: Crystal Structure of Flg22 in Complex with The Fls2 and Bak1 Ectodomains
  457. 4mxc: Crystal Structure of Cmet in Complex with Novel Inhibitor
  458. 4nk9: Crystal Structure of Human Fibroblast Growth Factor Receptor 1 Kinase Domain in Complex with Pyrazolaminopyrimidine 1
  459. 4nka: Crystal Structure of Human Fibroblast Growth Factor Receptor 1 Kinase Domain in Complex with Pyrazolaminopyrimidine 2
  460. 4nks: Crystal Structure of Human Fibroblast Growth Factor Receptor 1 Kinase Domain in Complex with Pyrazolaminopyrimidine 3
  461. 4o3t: Zymogen Hgf-beta/met with Zymogen Activator Peptide Zap.14
  462. 4o3u: Zymogen Hgf-beta/met with Zymogen Activator Peptide Zap2.3
  463. 4oa2: Crystal Structure of The Bri1 Kinase Domain (865-1196) in Complex with Adp from Arabidopsis Thaliana
  464. 4oa6: Crystal Structure of The Apo-bri1 Kinase Domain (865-1160)
  465. 4oa9: Crystal Structure of The Bri1 Kinase Domain (865-1160) in Complex with Amppnp and Mn from Arabidopsis Thaliana
  466. 4oab: Crystal Structure of The Bri1 Kinase Domain (865-1160) in Complex with Atp from Arabidopsis Thaliana
  467. 4oac: Crystal Structure of The Bri1 Kinase Domain (865-1160) in Complex with Adp from Arabidopsis Thaliana
  468. 4oh4: Crystal Structure of Bri1 in Complex with Bki1
  469. 4otw: Her3 Pseudokinase Domain Bound to Bosutinib
  470. 4p2k: Structure of Ephrin Type-a Receptor 2
  471. 4p4c: Human Epha3 Kinase Domain in Complex with Quinoxaline Derivatives
  472. 4p59: Her3 Extracellular Domain in Complex with Fab Fragment of Mor09825
  473. 4p5q: Human Epha3 Kinase Domain in Complex with Quinoxaline Derivatives
  474. 4p5z: Human Epha3 Kinase Domain in Complex with Quinoxaline Derivatives
  475. 4pbv: Crystal Structure of Chicken Receptor Protein Tyrosine Phosphatase Sigma in Complex with Trkc
  476. 4pbw: Crystal Structure of Chicken Receptor Protein Tyrosine Phosphatase Sigma in Complex with Trkc
  477. 4pdo: Structure of Ephrin Type-a Receptor 2
  478. 4pmm: The Structure of Trka Kinase Bound to The Inhibitor N-(3-cyclopropyl- 1-phenyl-1h-pyrazol-5-yl)-2-{4-[3-methoxy-4-(4-methyl-1h-imidazol-1- Yl)phenyl]-1h-1,2,3-triazol-1-yl}acetamide
  479. 4pmp: The Structure of Trka Kinase Bound to The Inhibitor 1-cyclopropyl-1- [3-(1,3-thiazol-2-yl)benzyl]-3-[4-(trifluoromethoxy)phenyl]urea
  480. 4pms: The Structure of Trka Kinase Bound to The Inhibitor 4-naphthalen-1-yl- 1-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1h-pyrrolo[3,2-c]pyridine- 2-carboxylic Acid
  481. 4pmt: The Structure of Trka Kinase Bound to The Inhibitor N~4~-(4-morpholin- 4-ylphenyl)-n~6~-(pyridin-3-ylmethyl)pyrido[3,2-d]pyrimidine-4,6- Diamine
  482. 4q5j: Crystal Structure of Semet Derivative Bri1 in Complex with Bki1
  483. 4qq5: Crystal Structure of Fgf Receptor (fgfr) 4 Kinase Harboring The V550L Gate-keeper Mutation in Complex with Fiin-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming Fgfr Kinase Gate-keeper Mutations
  484. 4qqc: Crystal Structure of Fgf Receptor (fgfr) 4 Kinase Domain in Complex with Fiin-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming Fgfr Kinase Gate-keeper Mutations
  485. 4qqj: Crystal Structure of Fgf Receptor (fgfr) 4 Kinase Domain Harboring The V550L Gate-keeper Mutation
  486. 4qqt: Crystal Structure of Fgf Receptor (fgfr) 4 Tyrosine Kinase Domain
  487. 4qrc: Crystal Structure of The Tyrosine Kinase Domain of Fgf Receptor 4 in Complex with Ponatinib
  488. 4qt8: Crystal Structure of Ron Sema-psi-ipt1 Extracellular Domains in Complex with Msp Beta-chain
  489. 4r5s: Crystal Structure of Egfr 696-1022 L858R in Complex with Fiin-3
  490. 4r6v: Crystal Structure of Fgf Receptor (fgfr) 4 Kinase Harboring The V550L Gate-keeper Mutation in Complex with Fiin-3, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming Fgfr Kinase Gate-keeper Mutations
  491. 4ra0: An Engineered Axl 'decoy Receptor' Effectively Silences The Gas6-axl Signaling Axis
  492. 4tks: Native-sad Phasing for Human Egfr Kinase Domain.
  493. 4trl: Structure of Ephrin Type-a Receptor 2
  494. 4tye: Structural Analysis of The Human Fibroblast Growth Factor Receptor 4 Kinase
  495. 4tyg: Structural Analysis of The Human Fibroblast Growth Factor Receptor 4 Kinase
  496. 4tyi: Structural Analysis of The Human Fibroblast Growth Factor Receptor 4
  497. 4tyj: Structural Analysis of The Human Fibroblast Growth Factor Receptor 4 Kinase
  498. 4u0i: Crystal Structure of Kit in Complex with Ponatinib
  499. 4ux8: Ret Recognition of Gdnf-gfralpha1 Ligand by a Composite Binding Site Promotes Membrane-proximal Self-association
  500. 4w4z: Structure of The Epha4 Lbd in Complex with Peptide
  501. 4w50: Structure of The Epha4 Lbd in Complex with Peptide
  502. 4wkq: 1.85 Angstrom Structure of Egfr Kinase Domain with Gefitinib
  503. 4wrg: 1.9 Angstrom Structure of Egfr Kinase Domain
  504. 4wun: Structure of Fgfr1 in Complex with Azd4547 (n-{3-[2-(3,5- Dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5- Dimethylpiperazin-1-yl]benzamide) at 1.65 Angstrom
  505. 4rj4: Egfr Kinase (T790M/L858R) with Inhibitor Compound 6
  506. 4rj5: Egfr Kinase (T790M/L858R) with Inhibitor Compound 5
  507. 4rj6: Egfr Kinase (T790M/L858R) with Inhibitor Compound 4
  508. 4rj7: Egfr Kinase (T790M/L858R) with Inhibitor Compound 1
  509. 4rj8: Egfr Kinase (T790M/L858R) with Inhibitor Compound 8
  510. 4uxq: Fgfr4 in Complex with Ponatinib
  511. 4riw: Crystal Structure of an Egfr/her3 Kinase Domain Heterodimer
  512. 4rix: Crystal Structure of an Egfr/her3 Kinase Domain Heterodimer Containing The Cancer-associated HER3-Q790R Mutation
  513. 4riy: Crystal Structure of an Egfr/her3 Kinase Domain Heterodimer Containing The Cancer-associated HER3-E909G Mutation
  514. 4x3j: Selection of Fragments for Kinase Inhibitor Design: Decoration Is Key
  515. 4ckv: Crystal Structure of Vegfr-1 Domain 2 in Presence of Zn
  516. 4cl7: Crystal Structure of Vegfr-1 Domain 2 in Presence of Cobalt
  517. 4crp: Solution Structure of a Trkaig2 Domain Construct for Use in Drug Discovery
  518. 4tt7: Crystal Structure of Human Alk with a Covalent Modification
  519. 4uwy: Fgfr1 Apo Structure
  520. 4uwz: Native Fgfr1 with an Inhibitor
  521. 4ux0: Fgfr1 Mutant with an Inhibitor
  522. 4uxl: Structure of Human Ros1 Kinase Domain in Complex with Pf-06463922
  523. 4xmo: Crystal Structure of C-met in Complex with (r)-5-(8-fluoro-3-(1- Fluoro-1-(3-methoxyquinolin-6-yl)ethyl)-[1,2,4]triazolo[4,3- A]pyridin-6-yl)-3-methylisoxazole
  524. 4xyf: Crystal Structure of C-met in Complex with (s)-5-(8-fluoro-3-(1-(3-(2- Methoxyethoxy)quinolin-6-yl)ethyl)-[1,2,4]triazolo[4,3-a]pyridin-6- Yl)-3-methylisoxazole
  525. 4pgz: Structural Basis of Kit Activation by Oncogenic Mutations in The Extracellular Region Reveals a Zipper-like Mechanism for Ligand- Dependent or Oncogenic Receptor Tyrosine Kinase Activation
  526. 4r1v: Identification and Optimization of Pyridazinones as Potent and Selective C-met Kinase Inhibitors
  527. 4r1y: Identification and Optimization of Pyridazinones as Potent and Selective C-met Kinase Inhibitor
  528. 5am6: Native Fgfr1 with an Inhibitor
  529. 5am7: Fgfr1 Mutant with an Inhibitor
  530. 3wsq: Structure of Her2 with an Fab
  531. 4xlv: Crystal Structure of The Activated Insulin Receptor Tyrosine Kinase Dimer
  532. 4xcu: Crystal Structure of Fgfr4 with an Irreversible Inhibitor
  533. 3wlw: Molecular Architecture of The Erbb2 Extracellular Domain Homodimer
  534. 3wzd: Kdr in Complex with Ligand Lenvatinib
  535. 3wze: Kdr in Complex with Ligand Sorafenib
  536. 4d2r: Human Igf in Complex with a DYRK1B Inhibitor
  537. 4rt7: Crystal Structure of Flt3 with a Small Molecule Inhibitor
  538. 4rwi: Crystal Structure of V561M Fgfr1 Gatekeeper Mutation (C488A, C584S, V561M), Apo
  539. 4rwj: Crystal Structure of Fgfr1 (C488A, C584S) in Complex with Azd4547 (n- {3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5- Dimethylpiperazin-1-yl]benzamide)
  540. 4rwk: Crystal Structure of V561M Fgfr1 Gatekeeper Mutation (C488A, C584S, V561M) in Complex with N-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h- Pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide (azd4547)
  541. 4rwl: Crystal Structure of Fgfr1 (C488A, C584C) in Complex with 6-(7-((1- Aminocyclopropyl) Methoxy)-6-methoxyquinolin-4-yloxy)-n-methyl-1- Naphthamide (e3810)
  542. 4twn: Human Epha3 Kinase Domain in Complex with Birb796
  543. 4two: Human Epha3 Kinase Domain in Complex with Compound 164
  544. 4xuf: Crystal Structure of The Flt3 Kinase Domain Bound to The Inhibitor Quizartinib (ac220)
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