EC 2.7.6.3 - ATP:2- amino- 4- hydroxy- 6- hydroxymethyl- 7,8- dihydropteridine 6'- diphosphotransferase (2- amino- 4- hydroxy- 6- hydroxymethyldihydropteridine diphosphokinase)

3D structures of EC 2.7.6.3 - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1dy3: Ternary Complex of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase from Escherichia Coli with Atp and a Substrate Analogue.
2. 1eq0: Solution Structure of 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Complexed with Mgamppcp
3. 1eqm: Crystal Structure of Binary Complex of 6-hydroxymethyl-7,8- Dihydropterin Pyrophosphokinase with Adenosine-5'- Diphosphate
4. 1ex8: Crystal Structure of 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Complexed with HP4A, The Two-substrate- Mimicking Inhibitor
5. 1f9h: Crystal Structure of The Ternary Complex of E. Coli HPPK(R92A) with Mgampcpp and 6-hydroxymethyl-7,8- Dihydropterin at 1.50 Angstrom Resolution
6. 1g4c: Crystal Structure of a Complex of HPPK(R92A) from E.coli with Mg2+ at 1.65 Angstrom Resolution
7. 1hka: 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase
8. 1hq2: Crystal Structure of a Ternary Complex of E.coli HPPK(R82A) with Mgampcpp and 6-hydroxymethyl-7,8-dihydropterin at 1.25 Angstrom Resolution
9. 1im6: Crystal Structure of Unligated HPPK(R82A) from E.coli at 1.74 Angstrom Resolution
10. 1kbr: Crystal Structure of Unligated HPPK(R92A) from E.coli at 1.55 Angstrom Resolution
11. 3kuh: Crystal Structure of E. Coli HPPK(H115A) in Complex with Ampcpp and Hp
12. 3kug: Crystal Structure of E. Coli HPPK(H115A)
13. 3kue: Crystal Structure of E. Coli HPPK(E77A)
14. 3ip0: Crystal Structure of E. Coli Hppk in Complx with Mgampcpp and 6-hydroxymethylpterin/6-carboxypterin
15. 3ilo: Crystal Structure of E. Coli HPPK(D97A) in Complex with Mgampcpp and 6-hydroxymethyl-7,8-dihydropterin
16. 3ill: Crystal Structure of E. Coli HPPK(D97A)
17. 3ilj: Crystal Structure of E. Coli HPPK(D95A) in Complex with Mgampcpp
18. 3ili: Crystal Structure of E. Coli HPPK(D95A)
19. 1q0n: Crystal Structure of a Ternary Complex of 6-hydroxymethyl-7, 8-dihydropterin Pyrophosphokinase from E. Coli with Mgampcpp and 6-hydroxymethyl-7,8-dihydropterin at 1.25 Angstrom Resolution
20. 3ht0: Crystal Structure of E. Coli HPPK(F123A) in Complex with Mgampcpp
21. 3hsz: Crystal Structure of E. Coli HPPK(F123A)
22. 3hsj: Crystal Structure of E. Coli HPPK(N55A)
23. 3hsg: Crystal Structure of E. Coli HPPK(Y53A) in Complex with Mgampcpp
24. 3hsd: Crystal Structure of E. Coli HPPK(Y53A)
25. 3hd2: Crystal Structure of E. Coli HPPK(Q50A) in Complex with Mgampcpp and Pterin
26. 3hd1: Crystal Structure of E. Coli HPPK(N10A) in Complex with Mgampcpp
27. 3hcx: Crystal Structure of E. Coli HPPK(N10A)
28. 1rao: Crystal Structure of a Ternary Complex of E. Coli Hppk with Amp and 6-hydroxymethylpterin-diphosphate at 1.56 Angstrom Resolution
29. 1rb0: Crystal Structure of a Binary Complex of E. Coli Hppk with 6-hydroxymethylpterin-diphosphate at 1.35 Angstrom Resolution
30. 1rtz: Crystal Structure of E.coli APO-HPPK(V83G/DEL84-89) at 1.33 Angstrom Resolution
31. 1ru1: Crystal Structure of a Ternary Complex of E. Coli HPPK(V83G/DEL84-89) with Mgampcpp and 6-hydroxymethyl-7,8- Dihydropterin at 1.40 Angstrom Resolution (monoclinic Form)
32. 1ru2: Crystal Structure of a Ternary Complex of E.coli HPPK(V83G/DEL84-89) with Mgampcpp and 6- Hydroxymethylpterin at 1.48 Angstrom Resolution (orthorhombic Form)
33. 1tmj: Crystal Structure of E.coli APO-HPPK(W89A) at 1.45 Angstrom Resolution
34. 1tmm: Crystal Structure of Ternary Complex of E.coli HPPK(W89A) with Mgampcpp and 6-hydroxymethylpterin
35. 7kdr: Crystal Structure of Escherichia Coli Hppk in Complex with Bisubstrate Inhibitor Hp-75
36. 7kdo: Crystal Structure of Escherichia Coli Hppk in Complex with Bisubstrate Inhibitor Hp-73
37. 2bmb: X-ray Structure of The Bifunctional 6-hydroxymethyl-7,8- Dihydroxypterin Pyrophosphokinase Dihydropteroate Synthase from Saccharomyces Cerevisiae
38. 2qx0: Crystal Structure of Yersinia Pestis Hppk (ternary Complex)
39. 2cg8: The Bifunctional Dihydroneopterin Aldolase 6-hydroxymethyl- 7,8-dihydropterin Synthase from Streptococcus Pneumoniae
40. 6an6: Crystal Structure of Escherichia Coli Hppk in Complex with Bisubstrate Analogue Inhibitor Hp-72
41. 6an4: Crystal Structure of Escherichia Coli Hppk in Complex with Bisubstrate Analogue Inhibitor Hp-39 (J1F)
42. 2f63: Solution Structure of Hppk in Complex with Inhibitor Analogs Ampcpp and Hp-1
43. 2f65: Solution Structure of Hppk in Complex with Inhibitor Analog Ampcpp
44. 5z79: Crystal Structure Analysis of The Hppk-dhps in Complex with Substrates
45. 3ud5: Crystal Structure of E. Coli Hppk in Complex with Bisubstrate Analogue Inhibitor J1A
46. 3ude: Crystal Structure of E. Coli Hppk in Complex with Bisubstrate Analogue Inhibitor J1B
47. 3udv: Crystal Structure of E. Coli Hppk in Complex with Bisubstrate Analogue Inhibitor J1C
48. 3qbc: Structure and Design of a New Pterin Site Inhibitor of S. Aureus Hppk
49. 4f7v: Crystal Structure of E. Coli Hppk in Complex with Bisubstrate Analogue Inhibitor J1D (hp26)
50. 4m5g: The Identification, Analysis and Structure-based Development of Novel Inhibitors of 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase
51. 4m5h: The Identification, Analysis and Structure-based Development of Novel Inhibitors of 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase
52. 4m5i: The Identification, Analysis and Structure-based Development of Novel Inhibitors of 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase
53. 4m5j: The Identification, Analysis and Structure-based Development of Novel Inhibitors of 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase
54. 4m5k: The Identification, Analysis and Structure-based Development of Novel Inhibitors of 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase
55. 4m5l: The Identification, Analysis and Structure-based Development of Novel Inhibitors of 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase
56. 4m5m: The Identification, Analysis and Structure-based Development of Novel Inhibitors of 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase
57. 4m5n: The Identification, Analysis and Structure-based Development of Novel Inhibitors of 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase
58. 4pzv: Crystal Structure of Francisella Tularensis Hppk-dhps in Complex with Bisubstrate Analog Hppk Inhibitor J1D
59. 5etv: S. Aureus 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.72 Angstrom Resolution
60. 5ett: S. Aureus 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.55 Angstrom Resolution
61. 5ets: S. Aureus 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.95 Angstrom Resolution
62. 5etr: S. Aureus 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.32 Angstrom Resolution
63. 5etp: E. Coli 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.05 Angstrom Resolution
64. 5eto: E. Coli 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.07 Angstrom Resolution
65. 5etn: E. Coli 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.40 Angstrom Resolution
66. 5etm: E. Coli 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.46 Angstrom Resolution
67. 5etl: E. Coli 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.82 Angstrom Resolution
68. 5etk: E. Coli 6-hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.09 Angstrom Resolution
69. 4crj: Staphylococcus Aureus 7,8-dihydro-6-hydroxymethylpterin- Pyrophosphokinase in Complex with Ampcpp and an Inhibitor
70. 4cwb: Staphylococcus Aureus 7,8-dihydro-6-hydroxymethylpterin- Pyrophosphokinase in Complex with Ampcpp and an Inhibitor
71. 4cyu: Staphylococcus Aureus 7,8-dihydro-6-hydroxymethylpterin- Pyrophosphokinase in Complex with Ampcpp
72. 7mpy: Crystal Structure of Cytosolic Hppk-dhps from A.thaliana