EC 3.1.1.8 - acylcholine acylhydrolase (cholinesterase)

3D structures of EC 3.1.1.8 - cholinesterase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1p0i: Crystal Structure of Human Butyryl Cholinesterase
2. 1p0m: Crystal Structure of Human Butyryl Cholinesterase in Complex with a Choline Molecule
3. 1p0p: Crystal Structure of Soman-aged Human Butyryl Cholinesterase in Complex with The Substrate Analog Butyrylthiocholine
4. 1p0q: Crystal Structure of Soman-aged Human Butyryl Cholinesterase
5. 6rua: Structure of Recombinant Human Butyrylcholinesterase in Complex with a Coumarin-based Fluorescent Probe Linked to Sulfonamide Type Inhibitor.
6. 3dkk: Aged Form of Human Butyrylcholinesterase Inhibited by Tabun
7. 3djy: Nonaged Form of Human Butyrylcholinesterase Inhibited by Tabun
8. 1xlu: X-ray Structure of Di-isopropyl-phosphoro-fluoridate (dfp) Inhibited Butyrylcholinesterase after Aging
9. 1xlv: Ethylphosphorylated Butyrylcholinesterase (aged) Obtained by Reaction with Echothiophate
10. 1xlw: Diethylphosphorylated Butyrylcholinesterase (nonaged) Obtained by Reaction with Echothiophate
11. 2xmg: G117H Mutant of Human Butyrylcholinesterase in Complex with Vx
12. 2xmd: G117H Mutant of Human Butyrylcholinesterase in Complex with Echothiophate
13. 2xmc: G117H Mutant of Human Butyrylcholinesterase in Complex with Fluoride Anion
14. 2xmb: G117H Mutant of Human Butyrylcholinesterase in Complex with Sulfate
15. 2wsl: Aged Form of Human Butyrylcholinesterase Inhibited by Tabun Analogue Ta4
16. 2wil: Aged Form of Human Butyrylcholinesterase Inhibited by Tabun Analogue Ta5
17. 2wik: Nonaged Form of Human Butyrylcholinesterase Inhibited by Tabun Analogue Ta6
18. 2wij: Nonaged Form of Human Butyrylcholinesterase Inhibited by Tabun Analogue Ta5
19. 2wig: Nonaged Form of Human Butyrylcholinesterase Inhibited by Tabun Analogue Ta4
20. 2wif: Aged Form of Human Butyrylcholinesterase Inhibited by Tabun Analogue Ta1
21. 2wid: Nonaged Form of Human Butyrylcholinesterase Inhibited by Tabun Analogue Ta1
22. 2pm8: Crystal Structure of Recombinant Full Length Human Butyrylcholinesterase
23. 6xta: Recombinant Human Butyrylcholinesterase in Complex with (2s)-n-[2-(1- Benzylazepan-4-yl)ethyl]-2-(butylamino)-3-(1h-indol-3-yl)propanamide
24. 2j4c: Structure of Human Butyrylcholinesterase in Complex with 10mm Hgcl2
25. 6t9s: Human Butyrylcholinesterase in Complex with 2-(n-hydroxyimino)-n- [(1s)-3-{4-[(2-methyl-1h-imidazol-1-yl)methyl]-1h-1,2,3-triazol-1- Yl}-1- Phenylpropyl]acetamide
26. 6t9p: Human Butyrylcholinesterase in Complex with 2-(n-hydroxyimino)-n- [(1r)-3-{4-[(2-methyl-1h-imidazol-1-yl)methyl]-1h-1,2,3-triazol-1- Yl}-1- Phenylpropyl]acetamide
27. 2xqf: X-ray Structure of Human Butyrylcholinesterase Inhibited by Racemic Vx
28. 2xqg: X-ray Structure of Human Butyrylcholinesterase Inhibited by Racemic Vr
29. 2xqi: X-ray Structure of Human Butyrylcholinesterase Inhibited by Racemic Cvx
30. 2xqj: X-ray Structure of Human Butyrylcholinesterase Inhibited by Pure Enantiomer Vx-(r)
31. 2xqk: X-ray Structure of Human Butyrylcholinesterase Inhibited by Pure Enantiomer Vx-(s)
32. 3o9m: Co-crystallization Studies of Full Length Recombinant Bche with Cocaine Offers Insights into Cocaine Detoxification
33. 6sam: Structure of Human Butyrylcholinesterase in Complex with 1-(2,3- Dihydro-1h-inden2-yl)piperidin-3-yl N-phenyl Carbamate
34. 2y1k: Structure of Human Butyrylcholinesterase Inhibited by Cbdp ( 12h Soak): Phosphoserine Adduct
35. 6qae: Human Butyrylcholinesterase in Complex with (s)-n2-butyl-n1-(2- Cycloheptylethyl)-3-(1h-indol-3-yl)-n1,n2-dimethylpropane-1,2-diamine
36. 6qad: Human Butyrylcholinesterase in Complex with ((s)-2-(butylamino)-n-(2- (4-(dimethylamino)cyclohexyl)ethyl)-3-(1h-indol-3-yl)propanamide
37. 6qac: Human Butyrylcholinesterase in Complex with (s)-2-(butylamino)-n-(3- Cycloheptylpropyl)-3-(1h-indol-3-yl)propanamide
38. 6qab: Human Butyrylcholinesterase in Complex with (s)-n-(1-((2- Cycloheptylethyl)amino)-3-(1h-indol-3-yl)-1-oxopropan-2-yl)-n,n- Dimethylbutan-1-aminium
39. 6qaa: Human Butyrylcholinesterase in Complex with (s)-2-(butylamino)-n-(2- Cycloheptylethyl)-3-(1h-indol-3-yl)propanamide
40. 4aqd: Crystal Structure of Fully Glycosylated Human Butyrylcholinesterase
41. 4axb: Crystal Structure of Soman-aged Human Butyrylcholinesterase in Complex with 2-pam
42. 4b0o: Crystal Structure of Soman-aged Human Butyrylcholinesterase in Complex with Benzyl Pyridinium-4-methyltrichloroacetimidate
43. 4b0p: Crystal Structure of Soman-aged Human Butyrylcholinesterase in Complex with Methyl 2-(pentafluorobenzyloxyimino) Pyridinium
44. 6i2t: Cryoem Reconstruction of Full-length, Fully-glycosylated Human Butyrylcholinesterase Tetramer
45. 6i0c: Human Butyrylcholinesterase in Complex with The R Enantiomer of a Chlorotacrine-tryptophan Multi-target Inhibitor.
46. 6i0b: Human Butyrylcholinesterase in Complex with The S Enantiomer of a Chlorotacrine-tryptophan Multi-target Inhibitor.
47. 4bbz: Structure of Human Butyrylcholinesterase Inhibited by Cbdp ( 2-min Soak): Cresyl-phosphoserine Adduct
48. 6r6v: Structure of Recombinant Human Butyrylcholinesterase in Complex with a Fluorescent Coumarin-based Probe
49. 6r6w: Structure of Recombinant Human Butyrylcholinesterase in Complex with a Fluorescent Nbd-based Probe
50. 4bds: Human Butyrylcholinesterase in Complex with Tacrine
51. 6f7q: Human Butyrylcholinesterase Complexed with N-propargyliperidines
52. 6ez2: Human Butyrylcholinesterase Carbamylated.
53. 6eyf: Butyrylcolinesterase Expressed in Cho Cells Co-crystallised with a Rivastigmine Analogue
54. 6eul: Butyrylcolinesterase Expressed in Cho Cells Co-crystallised with a Rivastigmine Analogue
55. 6esy: Human Butyrylcholinesterase in Complex with Thioflavine T
56. 6esj: Human Butyrylcholinesterase in Complex with Propidium
57. 6eqq: Human Butyrylcholinesterase in Complex with Huprine 19
58. 6eqp: Human Butyrylcholinesterase in Complex with Ethopropazine
59. 6ep4: Human Butyrylcholinesterase in Complex with Decamethonium
60. 6emi: Crystal Structure of a Variant of Human Butyrylcholinesterase Expressed in Bacteria.
61. 4tpk: Human Butyrylcholinesterase in Complex with N-((1-(2,3-dihydro-1h- Inden-2-yl)piperidin-3-yl)methyl)-n-(2-methoxyethyl)-2-naphthamide
62. 5nn0: Crystal Structure of Hubche with N-((1-(2,3-dihydro-1h-inden-2-yl) Piperidin-3-yl)methyl)-n-(2-(dimethylamino)ethyl)-2-naphthamide.
63. 5lkr: Human Butyrylcholinesterase Complexed with N-propargyliperidines
64. 5k5e: Discovery and Structure-activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-based Virtual Screening
65. 5dyy: Crystal Structure of Human Butyrylcholinesterase in Complex with N- ((1-benzylpiperidin-3-yl)methyl)naphthalene-2-sulfonamide
66. 5dyw: Crystal Structure of Human Butyrylcholinesterase in Complex with N- ((1-benzylpiperidin-3-yl)methyl)-n-(2-methoxyethyl)naphthalene-2- Sulfonamide
67. 5dyt: Crystal Structure of Human Butyrylcholinesterase in Complex with N- ((1-benzylpiperidin-3-yl)methyl)-n-methylnaphthalene-2-sulfonamide
68. 4xii: X-ray Structure of Human Butyrylcholinesterase in Complex with N-((1- (2,3-dihydro-1h-inden-2-yl)piperidin-3-yl)methyl)-8-hydroxy-n-(2- Methoxyethyl)-5-nitroquinoline-7-carboxamide
69. 7bgc: Human Butyrylcholinesterase in Complex with a Tacrine-methylanacardate Hybrid Inhibitor
70. 7amz: Crystal Structure of Human Butyrylcholinesterase in Complex with N- ((2s,3r)-4-((2,2-dimethylpropyl)amino)-3-hydroxy-1-phenylbutan-2-yl)- 2,2-diphenylacetamide
71. 6zwi: Human Butyrylcholinesterase in Complex with ((6-((2e,4e)-5- (benzo[d][1,3]dioxol-5-yl)penta-2,4-dienamido)hexyl) Triphenylphosphonium Bromide)
72. 7awg: Crystal Structure of Human Butyrylcholinesterase in Complex with (2- ((1-(benzenesulfonyl)-1h-indol-4-yl)oxy)ethyl)(benzyl)amine
73. 7awh: Crystal Structure of Human Butyrylcholinesterase in Complex with Tert- Butyl 3-(((2-((1-(benzenesulfonyl)-1h-indol-4-yl)oxy)ethyl)amino) Methyl)piperidine-1-carboxylate
74. 7awi: Crystal Structure of Human Butyrylcholinesterase in Complex with Tert- Butyl 3-(((2-((1-benzyl-1h-indol-4-yl)oxy)ethyl)amino) Methyl]piperidine-1-carboxylate
75. 7aiy: Crystal Structure of Human Butyrylcholinesterase in Complex with 2-{1- [4-(12-amino-3-chloro-6,7,10,11-tetrahydro-7,11- Methanocycloocta[b]quinolin-9-yl)butyl]-1h-1,2,3-triazol-4-yl}-n-[4- Hydroxy-3-methoxybenzyl]acetamide