EC 3.2.1.52 - β- N- acetyl- D- hexosaminide N- acetylhexosaminohydrolase (\xCE\xB2- N- acetylhexosaminidase)

3D structures of EC 3.2.1.52 - \xCE\xB2-N-acetylhexosaminidase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1c7s: Beta-n-acetylhexosaminidase Mutant D539A Complexed with Di- N-acetyl-beta-d-glucosamine (chitobiase)
2. 1c7t: Beta-n-acetylhexosaminidase Mutant E540D Complexed with Di- N Acetyl-d-glucosamine (chitobiase)
3. 1hp4: Crystal Structure of Streptomyces Plicatus Beta-n- Acetylhexosaminidase
4. 1hp5: Streptomyces Plicatus Beta-n-acetylhexosaminidase Complexed with Intermediate Analouge Nag-thiazoline
5. 1jak: Streptomyces Plicatus Beta-n-acetylhexosaminidase in Complex with (2r,3r,4s,5r)-2-acetamido-3,4-dihydroxy-5- Hydroxymethyl-piperidinium Chloride (ifg)
6. 3nvd: Structure of Ybbd in Complex with Pugnac
7. 3nsn: Crystal Structure of Insect Beta-n-acetyl-d-hexosaminidase Ofhex1 Complexed with Tmg-chitotriomycin
8. 3nsm: Crystal Structure of Insect Beta-n-acetyl-d-hexosaminidase Ofhex1 from Ostrinia Furnacalis
9. 1m01: Wildtype Streptomyces Plicatus Beta-hexosaminidase in Complex with Product (glcnac)
10. 1m03: Mutant Streptomyces Plicatus Beta-hexosaminidase (D313A) in Complex with Product (glcnac)
11. 1m04: Mutant Streptomyces Plicatus Beta-hexosaminidase (D313N) in Complex with Product (glcnac)
12. 1nou: Native Human Lysosomal Beta-hexosaminidase Isoform B
13. 1now: Human Lysosomal Beta-hexosaminidase Isoform B in Complex with (2r,3r,4s,5r)-2-acetamido-3,4-dihydroxy-5- Hydroxymethyl-piperidinium Chloride (galnac-isofagomine)
14. 1np0: Human Lysosomal Beta-hexosaminidase Isoform B in Complex with Intermediate Analogue Nag-thiazoline
15. 1o7a: Human Beta-hexosaminidase B
16. 1qba: Bacterial Chitobiase, Glycosyl Hydrolase Family 20
17. 1qbb: Bacterial Chitobiase Complexed with Chitobiose (dinag)
18. 3gsm: Vibrio Cholerae Family 3 Glycoside Hydrolase (nagz) Bound to N-valeryl-pugnac
19. 3gs6: Vibrio Cholerea Family 3 Glycoside Hydrolase (nagz)in Complex with N-butyryl-pugnac
20. 3gh7: Crystal Structure of Beta-hexosaminidase from Paenibacillus Sp. Ts12 in Complex with Galnac
21. 3gh5: Crystal Structure of Beta-hexosaminidase from Paenibacillus Sp. Ts12 in Complex with Glcnac
22. 3gh4: Crystal Structure of Beta-hexosaminidase from Paenibacillus Sp. Ts12
23. 1tr9: Structure of Beta-hexosaminidase from Vibrio Cholerae
24. 2xj7: Btgh84 in Complex with 6-acetamido-6-deoxy-castanospermine
25. 2x0y: Screening-based Discovery of Drug-like O-glcnacase Inhibitor Scaffolds
26. 2x0h: Btgh84 Michaelis Complex
27. 1y65: Crystal Structure of Beta-hexosaminidase from Vibrio Cholerae in Complex with N-acetyl-d-glucosamine to a Resolution of 1.85
28. 2wzi: Btgh84 D243N in Complex with 5f-oxazoline
29. 2wzh: Btgh84 D242N in Complex with Meumb-derived Oxazoline
30. 1yht: Crystal Structure Analysis of Dispersin B
31. 2wca: Btgh84 in Complex with N-butyl Pugnac
32. 2wb5: Glcnacstatins Are Nanomolar Inhibitors of Human O-glcnacase Inducing Cellular Hyper-o-glcnacylation
33. 2w67: Btgh84 in Complex with Fma34
34. 2w66: Btgh84 in Complex with Hq602
35. 2w4x: Btgh84 in Complex with Stz
36. 2w1n: Cohesin and Fibronectin Type-iii Double Module Construct from The Clostridium Perfringens Glycoside Hydrolase GH84C
37. 2vvs: Btgh84 Structure in Complex with Pugnac
38. 2vvn: Btgh84 in Complex with Nh-butylthiazoline
39. 7cbo: Crystal Structure of Beta-n-acetylhexosaminidase Am0868 from Akkermansia Muciniphila in Complex with Glcnac
40. 7cbn: Crystal Structure of Beta-n-acetylhexosaminidase Am0868 from Akkermansia Muciniphila
41. 2v5d: Structure of a Family 84 Glycoside Hydrolase and a Family 32 Carbohydrate-binding Module in Tandem from Clostridium Perfringens.
42. 2v5c: Family 84 Glycoside Hydrolase from Clostridium Perfringens, 2.1 Angstrom Structure
43. 2chn: Bacteroides Thetaiotaomicron Hexosaminidase with O- Glcnacase Activity - Nag-thiazoline Complex
44. 2cho: Bacteroides Thetaiotaomicron Hexosaminidase with O- Glcnacase Activity
45. 2oxn: Vibrio Cholerae Family 3 Glycoside Hydrolase (nagz) in Complex with Pugnac
46. 6yhh: X-ray Structure of Flavobacterium Johnsoniae Chitobiase (fjgh20)
47. 2o4e: The Solution Structure of a Protein-protein Interaction Module from a Family 84 Glycoside Hydrolase of Clostridium Perfringens
48. 2epk: N-acetyl-b-d-glucosaminidase (gcna) from Streptococcus Gordonii
49. 2epl: N-acetyl-b-d-glucosaminidase (gcna) from Streptococcus Gordonii
50. 2epm: N-acetyl-b-d-glucoasminidase (gcna) from Stretococcus Gordonii
51. 2epn: N-acetyl-b-d-glucosaminidase (gcna) from Streptococcus Gordonii
52. 2epo: N-acetyl-b-d-glucosaminidase (gcna) from Streptococcus Gordonii
53. 2gjx: Crystallographic Structure of Human Beta-hexosaminidase a
54. 2gk1: X-ray Crystal Structure of Ngt-bound Hexa
55. 2j47: Bacteroides Thetaiotaomicron Gh84 O-glcnacase in Complex with a Imidazole-pugnac Hybrid Inhibitor
56. 2j4g: Bacteroides Thetaiotaomicron Gh84 O-glcnacase in Complex with N-butyl-thiazoline Inhibitor
57. 2jiw: Bacteroides Thetaiotaomicron Gh84 O-glcnacase in Complex with 2-acetylamino-2-deoxy-1-epivalienamine
58. 3lmy: The Crystal Structure of Beta-hexosaminidase B in Complex with Pyrimethamine
59. 2xpk: Cell-penetrant, Nanomolar O-glcnacase Inhibitors Selective against Lysosomal Hexosaminidases
60. 2xsa: Ogoga Apostructure
61. 2xsb: Ogoga Pugnac Complex
62. 6k35: Crystal Structure of Gh20 Exo Beta-n-acetylglucosaminidase from Vibrio Harveyi in Complex with Nag-thiazoline
63. 6jtl: Crystal Structure of Nagz from Neisseria Gonorrhoeae in Complex with Zinc Ion
64. 6jtk: Crystal Structure of Nagz from Neisseria Gonorrhoeae in Complex with N-trifluoroacetyl-d-glucosamine
65. 6jtj: Crystal Structure of Nagz from Neisseria Gonorrhoeae in Complex with N-acetylglucosamine
66. 6jti: Crystal Structure of Native Nagz from Neisseria Gonorrhoeae
67. 3rcn: Crystal Structure of Beta-n-acetylhexosaminidase from Arthrobacter Aurescens
68. 2xm1: Btgh84 in Complex with N-acetyl Gluconolactam
69. 2xm2: Btgh84 in Complex with Lognac
70. 3ozp: Crystal Structure of Insect Beta-n-acetyl-d-hexosaminidase Ofhex1 Complexed with Pugnac
71. 2yl8: Inhibition of The Pneumococcal Virulence Factor Strh and Molecular Insights into N-glycan Recognition and Hydrolysis
72. 2yla: Inhibition of The Pneumococcal Virulence Factor Strh and Molecular Insights into N-glycan Recognition and Hydrolysis
73. 2yl5: Inhibition of The Pneumococcal Virulence Factor Strh and Molecular Insights into N-glycan Recognition and Hydrolysis
74. 2yl6: Inhibition of The Pneumococcal Virulence Factor Strh and Molecular Insights into N-glycan Recognition and Hydrolysis
75. 2yl9: Inhibition of The Pneumococcal Virulence Factor Strh and Molecular Insights into N-glycan Recognition and Hydrolysis
76. 2yll: Inhibition of The Pneumococcal Virulence Factor Strh and Molecular Insights into N-glycan Recognition and Hydrolysis
77. 3ozo: Crystal Structure of Insect Beta-n-acetyl-d-hexosaminidase Ofhex1 Complexed with Ngt
78. 3rpm: Crystal Structure of The First Gh20 Domain of a Novel Beta-n-acetyl- Hexosaminidase Strh from Streptococcus Pneumoniae R6
79. 6q63: Bt0459
80. 2ydq: Cpoga D298N in Complex with Hoga-derived O-glcnac Peptide
81. 2ydr: Cpoga D298N in Complex with P53-derived O-glcnac Peptide
82. 3s6t: Crystal Structure of Insect Beta-n-acetyl-d-hexosaminidase Ofhex1 V327G Complexed with Pugnac
83. 3sur: Crystal Structure of Beta-hexosaminidase from Paenibacillus Sp. Ts12 in Complex with Nag-thiazoline.
84. 3sus: Crystal Structure of Beta-hexosaminidase from Paenibacillus Sp. Ts12 in Complex with Gal-nag-thiazoline
85. 3sut: Crystal Structure of Beta-hexosaminidase from Paenibacillus Sp. Ts12 in Complex with Pugnac
86. 3suu: Crystal Structure of Beta-hexosaminidase from Paenibacillus Sp. Ts12 in Complex with Gal-pugnac
87. 3suv: Crystal Structure of Beta-hexosaminidase from Paenibacillus Sp. Ts12 in Complex with Nhac-dnj
88. 3suw: Crystal Structure of Beta-hexosaminidase from Paenibacillus Sp. Ts12 in Complex with Nhac-cas
89. 4ais: A Complex Structure of Btgh84
90. 4aiu: A Complex Structure of Btgh84
91. 4g6c: Crystal Structure of Beta-hexosaminidase 1 from Burkholderia Cenocepacia J2315
92. 6k5j: Structure of a Glycoside Hydrolase Family 3 Beta-n- Acetylglucosaminidase from Paenibacillus Sp. Str. Fpu-7
93. 6jeb: Crystal Structure of a Beta-n-acetylhexosaminidase
94. 6jea: Crystal Structure of a Beta-n-acetylhexosaminidase
95. 6je8: Crystal Structure of a Beta-n-acetylhexosaminidase
96. 4gnv: Crystal Structure of Beta-hexosaminidase 1 from Burkholderia Cenocepacia J2315 with Bound N-acetyl-d-glucosamine
97. 2ltj: Conformational Analysis of Strh, The Surface-attached Exo- Beta-d-n- Acetylglucosaminidase from Streptococcus Pneumoniae
98. 3vtr: Crystal Structure of Insect Beta-n-acetyl-d-hexosaminidase Ofhex1 E328A Complexed with Tmg-chitotriomycin
99. 4gvf: Crystal Structure of Salmonella Typhimurium Family 3 Glycoside Hydrolase (nagz) Bound to Glcnac
100. 4gvg: Crystal Structure of Salmonella Typhimurium Family 3 Glycoside Hydrolase (nagz)
101. 4gvh: Crystal Structure of Salmonella Typhimurium Family 3 Glycoside Hydrolase (nagz) Covalently Bound to 5-fluoro-glcnac.
102. 4gvi: Crystal Structure of Mutant (D248N) Salmonella Typhimurium Family 3 Glycoside Hydrolase (nagz) in Complex with Glcnac-1,6-anhmurnac
103. 4hzm: Crystal Structure of Salmonella Typhimurium Family 3 Glycoside Hydrolase (nagz) Bound to N-[(3s,4r,5r,6r)-4,5-dihydroxy-6- (hydroxymethyl)piperidin-3-yl]butanamide
104. 4az5: Differential Inhibition of The Tandem Gh20 Catalytic Modules in The Pneumococcal Exo-beta-d-n-acetylglucosaminidase, Strh
105. 4az6: Differential Inhibition of The Tandem Gh20 Catalytic Modules in The Pneumococcal Exo-beta-d-n-acetylglucosaminidase, Strh
106. 4az7: Differential Inhibition of The Tandem Gh20 Catalytic Modules in The Pneumococcal Exo-beta-d-n-acetylglucosaminidase, Strh
107. 4azb: Differential Inhibition of The Tandem Gh20 Catalytic Modules in The Pneumococcal Exo-beta-d-n- Acetylglucosaminidase, Strh
108. 4azg: Differential Inhibition of The Tandem Gh20 Catalytic Modules in The Pneumococcal Exo-beta-d-n- Acetylglucosaminidase, Strh
109. 4azh: Differential Inhibition of The Tandem Gh20 Catalytic Modules in The Pneumococcal Exo-beta-d-n-acetylglucosaminidase, Strh
110. 4azi: Differential Inhibition of The Tandem Gh20 Catalytic Modules in The Pneumococcal Exo-beta-d-n-acetylglucosaminidase, Strh
111. 6ezt: Crystal Structure of Gh20 Exo Beta-n-acetylglucosaminidase D437A Inactive Mutant from Vibrio Harveyi
112. 6ezs: Crystal Structure of Gh20 Exo Beta-n-acetylglucosaminidase from Vibrio Harveyi in Complex with N-acetylglucosamine
113. 6ezr: Crystal Structure of Gh20 Exo Beta-n-acetylglucosaminidase from Vibrio Harveyi
114. 6dte: Glcnac-inspired Cyclophellitol Bound to Nagz
115. 3wmb: Crystal Structure of Insect Beta-n-acetyl-d-hexosaminidase Ofhex1 Complexed with Naphthalimide Derivative Q1
116. 3wmc: Crystal Structure of Insect Beta-n-acetyl-d-hexosaminidase Ofhex1 Complexed with Naphthalimide Derivative Q2
117. 4c7d: Structure and Activity of The Gh20 Beta-n- Acetylhexosaminidase from Streptomyces Coelicolor A3(2)
118. 4c7f: Structure and Activity of The Gh20 Beta-n- Acetylhexosaminidase from Streptomyces Coelicolor A3(2)
119. 4c7g: Structure and Activity of The Gh20 Beta-n- Acetylhexosaminidase from Streptomyces Coelicolor A3(2)
120. 4mss: Crystal Structure of Burkholderia Cenocepacia Family 3 Glycoside Hydrolase (nagz) Bound to (3s,4r,5r,6s)-3-acetamido-4,5,6- Trihydroxyazepane
121. 5y1b: Crystal Structure of Insect Beta-n-acetyl-d-hexosaminidase Ofhex1 Complexed with a Berberine Derivative (sysu-00679)
122. 5y0v: Crystal Structure of Insect Beta-n-acetyl-d-hexosaminidase Ofhex1 Complexed with Berberine
123. 5utr: Crystal Structure of Burkholderia Cenocepacia Family 3 Glycoside Hydrolase (nagz) Bound to (3s,4r,5r,6s)-3-butyryl-4,5,6- Trihydroxyazepane
124. 5utq: Crystal Structure of Burkholderia Cenocepacia Family 3 Glycoside Hydrolase (nagz) Bound to Pugnac
125. 5utp: Crystal Structure of Burkholderia Cenocepacia Family 3 Glycoside Hydrolase (nagz) Bound to N-ethylbutyryl-pugnac
126. 5oxd: Complex of a C. Perfringens O-glcnacase with a Fragment Hit
127. 5oar: Crystal Structure of Native Beta-n-acetylhexosaminidase Isolated from Aspergillus Oryzae
128. 5mi7: Btgh84 Mutant with Covalent Modification by Ma4 in Complex with Pugnac
129. 5mi6: Btgh84 Mutant with Covalent Modification by Ma3 in Complex with Thiamet G
130. 5mi5: Btgh84 Mutant with Covalent Modification by Ma3 in Complex with Pugnac
131. 5mi4: Btgh84 Mutant with Covalent Modification by Ma3
132. 5ly7: Crystal Structure of Nagz H174A Mutant from Pseudomonas Aeruginosa in Complex with The Inhibitor 2-acetamido-1,2-dideoxynojirimycin
133. 5iob: Crystal Structure of Beta-n-acetylglucosaminidase-like Protein from Corynebacterium Glutamicum
134. 5g6t: Crystal Structure of Zn-containing Nagz H174A Mutant from Pseudomonas Aeruginosa
135. 5g5u: Crystal Structure of Nagz H174A Mutant from Pseudomonas Aeruginosa
136. 5g5k: Crystal Structure of Nagz from Pseudomonas Aeruginosa in Complex with The Inhibitor 2-acetamido-1,2-dideoxynojirimycin
137. 5g3r: Crystal Structure of Nagz from Pseudomonas Aeruginosa in Complex with N-acetylglucosamine and L-ala-1,6-anhydromurnac
138. 5g2m: Crystal Structure of Nagz from Pseudomonas Aeruginosa in Complex with N-acetylglucosamine
139. 5g1m: Crystal Structure of Nagz from Pseudomonas Aeruginosa
140. 5c0q: Crystal Structure of Zn Bound Cbsa from Thermotoga Neapolitana
141. 5bza: Crystal Structure of Cbsa from Thermotoga Neapolitana
142. 3wo8: Crystal Structure of The Beta-n-acetylglucosaminidase from Thermotoga Maritima
143. 5bu9: Crystal Structure of Beta-n-acetylhexosaminidase from Beutenbergia Cavernae Dsm 12333
144. 5bro: Crystal Structure of Modified Hexb (modb)
145. 5ac5: GH20C, Beta-hexosaminidase from Streptococcus Pneumoniae in Complex with Glcnac
146. 5ac4: GH20C, Beta-hexosaminidase from Streptococcus Pneumoniae in Complex with Galnac
147. 5abh: Structure of Gh84 with Ligand
148. 5abg: Structure of Gh84 with Ligand
149. 5a6k: GH20C, Beta-hexosaminidase from Streptococcus Pneumoniae in Complex with Gal-ngt
150. 5a6j: GH20C, Beta-hexosaminidase from Streptococcus Pneumoniae
151. 5a6a: GH20C, Beta-hexosaminidase from Streptococcus Pneumoniae in Complex with Ngt
152. 4zxl: Cpoga D298N in Complex with Drosophila Hcf -derived Thr-o-glcnac Peptide
153. 4zm6: A Unique Gcn5-related Glucosamine N-acetyltransferase Region Exist in The Fungal Multi-domain Gh3 Beta-n-acetylglucosaminidase
154. 4yyf: The Crystal Structure of a Glycosyl Hydrolase of Gh3 Family Member from [mycobacterium Smegmatis Str. Mc2 155
155. 7vi6: Crystal Structure of Gh3 Beta-n-acetylhexosaminidase Amuc_2109 from Akkermansia Muciniphila
156. 7vi7: Crystal Structure of Gh3 Beta-n-acetylhexosaminidase Amuc_2109 from Akkermansia Muciniphila in Complex with Glcnac