EC 3.3.2.6 - (7 E ,9 E ,11 Z ,14 Z ) - (5 S ,6 S ) - 5,6- epoxyicosa- 7,9,11,14- tetraenoate hydrolase (leukotriene- A ₄ hydrolase)

3D structures of EC 3.3.2.6 - leukotriene-A4 hydrolase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1gw6: Structure of Leukotriene A4 Hydrolase D375N Mutant
2. 1h19: Structure of [E271Q] Leukotriene A4 Hydrolase
3. 1hs6: Structure of Leukotriene A4 Hydrolase Complexed with Bestatin.
4. 3fun: Leukotriene A4 Hydrolase in Complex with {4-[(2r)- Pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen-3-ylphenyl) Methanone
5. 3fum: Leukotriene A4 Hydrolase in Complex with (r)-pyridin-4-yl[4- (2-pyrrolidin-1-ylethoxy)phenyl]methanol
6. 3ful: Leukotriene A4 Hydrolase in Complex with Pyridin-4-yl[4-(2-pyrrolidin- 1-ylethoxy)phenyl]methanone
7. 3fuk: Leukotriene A4 Hydrolase in Complex with 1-[2-(1h-indol-5- Yloxy)ethyl]piperidine-4-carboxylic Acid
8. 3fuj: Leukotriene A4 Hydrolase in Complex with 5-[2-(1h-pyrrol-1- Yl)ethoxy]-1h-indole
9. 3fui: Leukotriene A4 Hydrolase in Complex with N-benzyl-4-[(2r)- Pyrrolidin-2-ylmethoxy]aniline
10. 3fuh: Leukotriene A4 Hydrolase in Complex with Fragment 5- Hydroxyindole and Bestatin
11. 3fuf: Leukotriene A4 Hydrolase in Complex with Fragment 5- Fluoroindole and Bestatin
12. 3fue: Leukotriene A4 Hydrolase in Complex with Fragment 5- Chloroindole and Bestatin
13. 3fud: Leukotriene A4 Hydrolase in Complex with N-methyl-1-(2- Thiophen-2-ylphenyl)methanamine
14. 3fu6: Leukotriene A4 Hydrolase in Complex with Fragment (4- Thiophen-2-ylphenyl)methanamine
15. 3fu5: Leukotriene A4 Hydrolase in Complex with (5-thiophen-2- Ylthiophen-2-yl)methylamine
16. 3fu3: Leukotriene A4 Hydrolase in Complex with Fragment 4-(2- Amino-1,3-thiazol-4-yl)phenol
17. 3fu0: Leukotriene A4 Hydrolase in Complex with Fragment 4-(4- Fluorobenzoyl)pyridine
18. 3ftz: Leukotriene A4 Hydrolase in Complex with Fragment 2-(pyridin-3- Ylmethoxy)aniline
19. 3fty: Leukotriene A4 Hydrolase in Complex with Fragment 3- (benzyloxy)pyridin-2-amine
20. 3ftx: Leukotriene A4 Hydrolase in Complex with Dihydroresveratrol and Bestatin
21. 3ftw: Leukotriene A4 Hydrolase in Complex with Fragments N- (pyridin-3-ylmethyl)aniline and Acetate
22. 3ftv: Leukotriene A4 Hydrolase in Complex with Fragment N- (pyridin-3-ylmethyl)aniline
23. 3ftu: Leukotriene A4 Hydrolase in Complex with Dihydroresveratrol
24. 3fts: Leukotriene A4 Hydrolase in Complex with Resveratrol
25. 3fhe: Leukotriene A4 Hydrolase Complexed with Inhibitor N-[3-(4- Benzylphenoxy)propyl]-n-methyl-beta-alanine.
26. 3fh8: Leukotriene A4 Hydrolase Complexed with Inhibitor 1-[2-(4- Benzylphenoxy)ethyl]pyrrolidine.
27. 3fh7: Leukotriene A4 Hydrolase Complexed with Inhibitor 4-[(2s)-2-{[4-(4- Chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate.
28. 3fh5: Leukotriene A4 Hydrolase Complexed with Inhibitor (2r)-2-[(4- Benzylphenoxy)methyl]pyrrolidine.
29. 1sqm: Structure of [R563A] Leukotriene A4 Hydrolase
30. 3chs: Crystal Structure of Leukotriene A4 Hydrolase in Complex with (2s)-2-amino-5-[[4-[(2s)-2-hydroxy-2-phenyl- Ethoxy]phenyl]amino]-5-oxo-pentanoic Acid
31. 3chr: Crystal Structure of Leukotriene A4 Hydrolase in Complex with 4-amino-n-[4-(phenylmethoxy)phenyl]-butanamide
32. 3chq: Crystal Structure of Leukotriene A4 Hydrolase in Complex with N5-[4-(phenylmethoxy)phenyl]-l-glutamine
33. 3chp: Crystal Structure of Leukotriene A4 Hydrolase in Complex with (3s)-3-amino-4-oxo-4-[(4-phenylmethoxyphenyl) Amino]butanoic Acid
34. 3cho: Crystal Structure of Leukotriene A4 Hydrolase in Complex with 2-amino-n-[4-(phenylmethoxy)phenyl]-acetamide
35. 3b7u: Leukotriene A4 Hydrolase Complexed with Kelatorphan
36. 3b7t: [E296Q]LTA4H in Complex with Arg-ala-arg Substrate
37. 3b7s: [E296Q]LTA4H in Complex with Rsr Substrate
38. 3b7r: Leukotriene A4 Hydrolase Complexed with Inhibitor Rb3040
39. 2vj8: Complex of Human Leukotriene A4 Hydrolase with a Hydroxamic Acid Inhibitor
40. 2r59: Leukotriene A4 Hydrolase Complexed with Inhibitor Rb3041
41. 2xpy: Structure of Native Leukotriene A4 Hydrolase from Saccharomyces Cerevisiae
42. 2xpz: Structure of Native Yeast Lta4 Hydrolase
43. 2xq0: Structure of Yeast Lta4 Hydrolase in Complex with Bestatin
44. 6o5h: The Effect of Modifier Structure on The Activation of Leukotriene A4 Hydrolase Aminopeptidase Activity.
45. 3u9w: Structure of Human Leukotriene A4 Hydrolase in Complex with Inhibitor SC57461A
46. 4dpr: Structure of Human Leukotriene A4 Hydrolase in Complex with Inhibitor Captopril
47. 4gaa: Structure of Leukotriene A4 Hydrolase from Xenopus Laevis Complexed with Inhibitor Bestatin
48. 6end: Lta4 Hydrolase in Complex with Compound15
49. 6enc: Lta4 Hydrolase in Complex with Compound11
50. 6enb: Lta4 Hydrolase (E297Q) Mutant in Complex with Pro-gly-pro Peptide
51. 4l2l: Human Leukotriene A4 Hydrolase Complexed with Ligand 4-(4- Benzylphenyl)thiazol-2-amine
52. 4mkt: Human Leukotriene A4 Hydrolase in Complex with Pro-gly-pro Analogue and 4-(4-benzylphenyl)thiazol-2-amine
53. 4ms6: Human Leukotriene A4 Hydrolase in Complex with Pro-gly-pro Analogue
54. 5nie: Crystal Structure of Human LTA4H Mutant R563A in Open Conformation
55. 5nid: Crystal Structure of Human LTA4H Mutant D375N in Open Conformation (crystal Form Ii)
56. 5nia: Crystal Structure of Human LTA4H Mutant D375N in Open Conformation (crystal Form I)
57. 5ni6: Crystal Structure of Human LTA4H Mutant D375N in Complex with Lta4
58. 5ni4: Crystal Structure of Human LTA4H Mutant E271A in Complex with Lta4 (crystal Form Ii)
59. 5ni2: Crystal Structure of Human LTA4H Mutant E271A in Complex with Lta4 (crystal Form I)
60. 5n3w: Crystal Structure of LTA4H Bound to a Selective Inhibitor against Ltb4 Generation
61. 5fwq: Apo Structure of Human Leukotriene A4 Hydrolase
62. 5bpp: Structure of Human Leukotriene A4 Hydrolase in Complex with Inhibitor 4az
63. 5aen: Structure of Human Leukotriene A4 Hydrolase in Complex with Inhibitor Dimethyl(2-(4-phenoxyphenoxy)ethyl)amine
64. 4r7l: Structure of Human Leukotriene A4 Hydrolase in Complex with Inhibitor H1
65. 4rsy: Crystal Structures of The Human Leukotriene A4 Hydrolase Complex with a Potential Inhibitor H7
66. 4rvb: Crystal Structure Analysis of The Human Leukotriene A4 Hydrolase
67. 7auz: Lta4 Hydrolase in Complex with Compound Lys006
68. 7av0: Lta4 Hydrolase in Complex with Compound R(13)
69. 7av1: Lta4 Hydrolase in Complex with Fragment2
70. 7av2: Lta4 Hydrolase in Complex with Fragment1