EC 3.4.11.18 - methionyl aminopeptidase

3D structures of EC 3.4.11.18 - methionyl aminopeptidase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1b59: Complex of Human Methionine Aminopeptidase-2 Complexed with Ovalicin
2. 1b6a: Human Methionine Aminopeptidase 2 Complexed with Tnp-470
3. 1bn5: Human Methionine Aminopeptidase 2
4. 1boa: Human Methionine Aminopeptidase 2 Complexed with Angiogenesis Inhibitor Fumagillin
5. 1c21: E. Coli Methionine Aminopeptidase: Methionine Complex
6. 1c22: E. Coli Methionine Aminopeptidase: Trifluoromethionine Complex
7. 1c23: E. Coli Methionine Aminopeptidase: Methionine Phosphonate Complex
8. 1c24: E. Coli Methionine Aminopeptidase: Methionine Phosphinate Complex
9. 1c27: E. Coli Methionine Aminopeptidase:norleucine Phosphonate Complex
10. 4mat: E.coli Methionine Aminopeptidase HIS79ALA Mutant
11. 1kq0: Human Methionine Aminopeptidase Type II in Complex with D- Methionine
12. 1kq9: Human Methionine Aminopeptidase Type II in Complex with L- Methionine
13. 1mat: Structure of The Cobalt-dependent Methionine Aminopeptidase from Escherichia Coli: a New Type of Proteolytic Enzyme
14. 3mx6: Crystal Structure of Methionine Aminopeptidase from Rickettsia Prowazekii Bound to Methionine
15. 3mr1: Crystal Structure of Methionine Aminopeptidase from Rickettsia Prowazekii
16. 3mat: E.coli Methionine Aminopeptidase Transition-state Inhibitor Complex
17. 1o0x: Crystal Structure of Methionine Aminopeptidase (tm1478) from Thermotoga Maritima at 1.90 a Resolution
18. 3iu9: M. Tuberculosis Methionine Aminopeptidase with Ni Inhibitor T07
19. 3iu8: M. Tuberculosis Methionine Aminopeptidase with Ni Inhibitor T03
20. 3iu7: M. Tuberculosis Methionine Aminopeptidase with Mn Inhibitor A02
21. 1qxw: Crystal Structure of Staphyloccocus Aureus in Complex with an Aminoketone Inhibitor 54135.
22. 1qxy: Crystal Structure of S. Aureus Methionine Aminopeptidase in Complex with a Ketoheterocycle 618
23. 1qxz: Crystal Structure of S. Aureus Methionine Aminopeptidase in Complex with a Ketoheterocycle Inhibitor 119
24. 1qzy: Human Methionine Aminopeptidase in Complex with Bengamide Inhibitor Laf153 and Cobalt
25. 1r58: Crystal Structure of Metap2 Complexed with A357300
26. 1r5g: Crystal Structure of Metap2 Complexed with A311263
27. 1r5h: Crystal Structure of Metap2 Complexed with A320282
28. 3fmr: Crystal Structure of an Encephalitozoon Cuniculi Methionine Aminopeptidase Type 2 with Angiogenesis Inhibitor Tnp470 Bound
29. 3fmq: Crystal Structure of an Encephalitozoon Cuniculi Methionine Aminopeptidase Type 2 with Angiogenesis Inhibitor Fumagillin Bound
30. 3fm3: Crystal Structure of an Encephalitozoon Cuniculi Methionine Aminopeptidase Type 2
31. 3d27: E. Coli Methionine Aminopeptidase with Fe Inhibitor W29
32. 1wkm: The Product Bound Form of The Mn(ii)loaded Methionine Aminopeptidase from Hyperthermophile Pyrococcus Furiosus
33. 1xgm: Methionine Aminopeptidase from Hyperthermophile Pyrococcus Furiosus
34. 1xgn: Methionine Aminopeptidase from Hyperthermophile Pyrococcus Furiosus
35. 1xgo: Methionine Aminopeptidase from Hyperthermophile Pyrococcus Furiosus
36. 1xnz: Crystal Structure of Mn(ii) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-chlorophenyl)furan-2- Carboxylic Acid
37. 1y1n: Identification of Sh3 Motif in M. Tuberculosis Methionine Aminopeptidase Suggests a Mode of Interaction with The Ribosome
38. 1yj3: Crystal Structure Analysis of Product Bound Methionine Aminopeptidase Type 1c from Mycobacterium Tuberculosis
39. 1yvm: E. Coli Methionine Aminopeptidase in Complex with Thiabendazole
40. 1yw7: H-metap2 Complexed with A444148
41. 1yw8: H-metap2 Complexed with A751277
42. 1yw9: H-metap2 Complexed with A849519
43. 2adu: Human Methionine Aminopeptidase Complex with 4-aryl-1,2,3- Triazole Inhibitor
44. 7a16: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with an Inhibitor GSK2229238A (compound 43)
45. 7a15: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with an Inhibitor GSK2224863A (compound 42)
46. 7a14: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with an Inhibitor GSK2218325A (compound 32)
47. 7a13: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with an Inhibitor GSK1978537A (compound 27)
48. 7a12: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with an Inhibitor GW557358X (compound 9)
49. 2b3h: Crystal Structure of Human Methionine Aminopeptidase Type I with a Third Cobalt in The Active Site
50. 2b3k: Crystal Structure of Human Methionine Aminopeptidase Type I in The Holo Form
51. 2b3l: Crystal Structure of Type I Human Methionine Aminopeptidase in The Apo Form
52. 2bb7: Mn Form of E. Coli Methionine Aminopeptidase in Complex with a Quinolinyl Sulfonamide Inhibitor
53. 2q96: E. Coli Methionine Aminopeptidase Mn-form with Inhibitor A18
54. 2q95: E. Coli Methionine Aminopeptidase Mn-form with Inhibitor A05
55. 2q94: E. Coli Methionine Aminopeptidase Mn-form with Inhibitor A04
56. 2q93: E. Coli Methionine Aminopeptidase Mn-form with Inhibitor B21
57. 2q92: E. Coli Methionine Aminopeptidase Mn-form with Inhibitor B23
58. 2p9a: E. Coli Methionine Aminopeptidase Dimetalated with Inhibitor Ye6
59. 2p99: E. Coli Methionine Aminopeptidase Monometalated with Inhibitor Ye6
60. 2p98: E. Coli Methionine Aminopeptidase Monometalated with Inhibitor Ye7
61. 2dfi: Crystal Structure of Pf-map(1-292)-c
62. 2oaz: Human Methionine Aminopeptidase-2 Complexed with Sb-587094
63. 2ea2: H-metap2 Complexed with A773812
64. 2ea4: H-metap2 Complexed with A797859
65. 2nq7: Crystal Structure of Type 1 Human Methionine Aminopeptidase in Complex with 3-(2,2-dimethylpropionylamino)pyridine-2- Carboxylic Acid Thiazole-2-ylamide
66. 2nq6: Crystal Structure of Human Methionine Aminopeptidase Type 1 in Complex with 3-tert-butoxycarbonylaminopyridine-2- Carboxylic Acid Thiazole-2-ylamide
67. 2mat: E.coli Methionine Aminopeptidase at 1.9 Angstrom Resolution
68. 2evc: Crystal Structure of E. Coli. Methionine Amino Peptidase in Complex with 5-(2-(trifluoromethyl)phenyl)furan-2- Carboxylic Acid
69. 2evm: Crystal Structure of Methionine Aminopeptidase in Complex with 5-(2,5-dichlorophenyl)furan-2-carboxylic Acid
70. 2evo: Crystal Structure of Methionine Amino Peptidase in Complex with N-cyclopentyl-n-(thiazol-2-yl)oxalamide
71. 2g6p: Crystal Structure of Truncated (delta 1-89) Human Methionine Aminopeptidase Type 1 in Complex with Pyridyl Pyrimidine Derivative
72. 2ga2: H-metap2 Complexed with A193400
73. 2gg0: Novel Bacterial Methionine Aminopeptidase Inhibitors
74. 2gg2: Novel Bacterial Methionine Aminopeptidase Inhibitors
75. 2gg3: Novel Bacterial Methionine Aminopeptidase Inhibitors
76. 2gg5: Novel Bacterial Methionine Aminopeptidase Inhibitors
77. 2gg7: Novel Bacterial Methionine Aminopeptidase Inhibitors
78. 2gg8: Novel Bacterial Methionine Aminopeptidase Inhibitors
79. 2gg9: Novel Bacterial Methionine Aminopeptidase Inhibitors
80. 2ggb: Novel Bacterial Methionine Aminopeptidase Inhibitors
81. 2ggc: Novel Bacterial Methionine Aminopeptidase Inhibitors
82. 2gtx: Structural Basis of Catalysis by Mononuclear Methionine Aminopeptidase
83. 2gu4: E. Coli Methionine Aminopeptidase in Complex with Nlep, 1: 0.5, Di-metalated
84. 2gu5: E. Coli Methionine Aminopeptidase in Complex with Nlep, 1: 1, Di-metalated
85. 2gu6: E. Coli Methionine Aminopeptidase in Complex with Nlep, 1: 2, Di-metalated
86. 2gu7: E. Coli Methionine Aminopeptidase Unliganded, 1:0.5
87. 5yxf: Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1c (C105L Mutant) in Complex with Methionine
88. 2gz5: Human Type 1 Methionine Aminopeptidase in Complex with Ovalicin at 1.1 Ang
89. 5yr7: Human Methionine Aminopeptidase Type 1b (F309L Mutant)
90. 5yr6: Human Methionine Aminopeptidase Type 1b (F309L Mutant) in Complex with Tnp470
91. 5yr5: Human Methionine Aminopeptidase Type 1b (F309L Mutant) in Complex with Ovalicin
92. 5yr4: Human Methionine Aminopeptidase Type 1b (F309M Mutant) in Complex with Tnp470
93. 5ypj: Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1c (C105N Mutant).
94. 5ypd: Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1c (C105N Mutant) in Complex with Methionine
95. 5yoi: Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1c (C105T Mutant) in Complex with Methionine
96. 5yoh: Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1c (C105M Mutant) in Complex with Methionine
97. 6lh7: Crystal Structure of Vibrio Cholerae Methionine Aminopeptidase with Partially Occupied Metals
98. 6ksg: Vibrio Cholerae Methionine Aminopeptidase in Holo Form
99. 6k26: Crystal Structure of Vibrio Cholerae Methionine Aminopeptidase
100. 3pka: M. Tuberculosis Metap with Bengamide Analog Y02, in Mn Form
101. 3pkb: M. Tuberculosis Metap with Bengamide Analog Y16, in Mn Form
102. 3pkc: M. Tuberculosis Metap with Bengamide Analog Y08, in Mn Form
103. 3pkd: M. Tuberculosis Metap with Bengamide Analog Y10, in Mn Form
104. 3pke: M. Tuberculosis Metap with Bengamide Analog Y10, in Ni Form
105. 3s6b: Crystal Structure of Methionine Aminopeptidase 1b from Plasmodium Falciparum, Pf10_0150
106. 3tav: Crystal Structure of a Methionine Aminopeptidase from Mycobacterium Abscessus
107. 6qej: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with an Inhibitor Thiophene-2-sulfonic Acid (4-fluoro-benzyl)-(4h-[1,2, 4]triazol-3-ylmethyl)-amide
108. 6qei: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with an Inhibitor 5,6-difluoro-3-(2-isopropoxy-4-piperazin-1-yl-phenyl)- 1h-indole-2-carboxylic Acid Amide
109. 6qeh: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with an Inhibitor 5-chloro-quinolin-8-ol
110. 6qeg: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with an Inhibitor 2-oxo-1-phenyl-pyrrolidine-3-carboxylic Acid (2- Thiophen-2-yl-ethyl)-amide
111. 6qef: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with an Inhibitor (s)-3-hydroxy-2-oxo-1-phenyl-pyrrolidine-3-carboxylic Acid 3-chloro-5-fluoro-benzylamide
112. 6qed: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex; with an Inhibitor (s)-3-hydroxy-2-oxo-1-(2-oxo-1,2,3,4-tetrahydro- Quinolin-6-yl)-pyrrolidine-3-carboxylic Acid 3-chloro-5-fluoro- Benzylamide
113. 3ror: Crystal Structure of C105S Mutant of Mycobacterium Tuberculosis Methionine Aminopeptidase
114. 4a6v: X-ray Structures of Oxazole Hydroxamate Ecmetap-mn Complexes
115. 4a6w: X-ray Structures of Oxazole Hydroxamate Ecmetap-mn Complexes
116. 6mrf: Crystal Structure of a Methionine Aminopeptidase Metap from Acinetobacter Baumannii
117. 3tb5: Crystal Structure of The Enterococcus Faecalis Methionine Aminopeptidase Apo Form
118. 4fli: Human Metap1 with Bengamide Analog Y16, in Mn Form
119. 4flj: Human Metap1 with Bengamide Analog Y08, in Mn Form
120. 4flk: Human Metap1 with Bengamide Analog Y10, in Mn Form
121. 4fll: Human Metap1 with Bengamide Analog Yz6, in Mn Form
122. 4fuk: Aminopeptidase from Trypanosoma Brucei
123. 6j0a: Crystal Structure of E. Coli Methionine Aminopeptidase Enzyme and Chaperone Trigger Factor Fitted into The Cryo-em Density Map of The Complex
124. 6izi: Crystal Structure of E. Coli Peptide Deformylase and Methionine Aminopeptidase Fitted into The Cryo-em Density Map of The Complex
125. 6iz7: E. Coli Methionine Aminopeptidase Crystal Structure Fitted into The Cryo-em Density Map of E. Coli 70s Ribosome in Complex with Methionine Aminopeptidase
126. 4hxx: Pyridinylpyrimidines Selectively Inhibit Human Methionine Aminopeptidase-1
127. 4iu6: Human Methionine Aminopeptidase in Complex with Fz1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1
128. 4fo7: Pseudomonas Aeruginosa Metap, in Mn Form
129. 4fo8: Pseudomonas Aeruginosa Metap with Met, in Mn Form
130. 4idy: Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1c in Complex with 2-hydroxyethyl Disulfide
131. 4iec: Cys105 Covalent Modification by 2-hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1c
132. 4if7: Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1c in Complex with Homocysteine-methyl Disulfide
133. 4ikr: Crystal Structure of Type 1 Human Methionine Aminopeptidase in Complex with 2-(4-(5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl) Piperazin-1-yl)ethanol
134. 4iks: Crystal Structure of Truncated (delta 1-89) Human Methionine Aminopeptidase Type 1 in Complex with N1-(5-chloro-6-methyl-2- (pyridin-2-yl)pyrimidin-4-yl)-n2-(6-(trifluoromethyl)pyridin-2-yl) Ethane-1,2-diamine
135. 4ikt: Crystal Structure of Truncated (delta 1-89) Human Methionine Aminopeptidase Type 1 in Complex with N1-(5-chloro-6-methyl-2- (pyridin-2-yl)pyrimidin-4-yl)-n2-(5-(trifluoromethyl)pyridin-2-yl) Ethane-1,2-diamine
136. 4iku: Crystal Structure of Truncated (delta 1-89) Human Methionine Aminopeptidase Type 1 in Complex with 2-((5-chloro-6-methyl-2- (pyridin-2-yl)pyrimidin-4-yl)amino)-3-phenylpropanamide
137. 4juq: Pseudomonas Aeruginosa Metap T2N Mutant, in Mn Form
138. 5ykp: Human Methionine Aminopeptidase Type 1b (F309M Mutant) in Complex with Ovalicin
139. 4pnc: E. Coli Methionine Aminopeptidase in Complex with Inhibitor 7-methoxy- 2-methylen-3,4-dihydronaphthalen-1(2h)-one
140. 5lyx: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex; with an Inhibitor 5-((r)-1-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl- Pyrrolidin-2-ylmethoxy)-isoquinoline
141. 5lyw: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex; with an Inhibitor 6-((r)-2-o-tolyloxymethyl-pyrrolidin-1-yl)-9h- Purine
142. 5ji6: Potent, Reversible Metap2 Inhibitors via Fbdd
143. 5jhu: Potent, Reversible Metap2 Inhibitors via Fbdd
144. 5jfr: Potent, Reversible Metap2 Inhibitors via Fragment Based Drug Discovery
145. 5d6f: Structure of Human Methionine Aminopeptidase-2 Complexed with Spiroepoxytriazole Inhibitor (+)-31b
146. 5d6e: Structure of Human Methionine Aminopeptidase 2 with Covalent Spiroepoxytriazole Inhibitor (-)-31b
147. 5cls: Structure of Human Methionine Aminopeptidase-2 Complexed with Spiroepoxytriazole Inhibitor (+)-31a
148. 4ook: Third Metal Bound M.tuberculosis Methionine Aminopeptidase
149. 4z7m: Novel Inhibitors of Bacterial Methionine Aminopeptidase with Broad- Spectrum Biochemical Activity
150. 4u1b: Hsmetap in Complex with (1-amino-2-propylpentyl)phosphonic Acid
151. 4u69: Hsmetap Complex with (1-amino-2-methylpentyl)phosphonic Acid
152. 4u6c: Hsmetap in Complex with [(1r)-1-amino-3-cyclopentylpropyl]phosphonic Acid
153. 4u6e: Hsmetap in Complex with (amino(phenyl)methyl)phosphonic Acid
154. 4u6j: Hsmetap in Complex with Methionine
155. 4u6w: Hsmetap (F220M) in Complex with 1-amino-2-propylpentyl]phosphonic Acid
156. 4u70: Hsmetap (F309M) in Complex with (1-amino-2-cyclohexylethyl)phosphonic Acid
157. 4u71: HSMETAP(F309M) in Complex with 1- Amino(cyclohexyl)methy)phosphonic Acid
158. 4u73: HSMETAP(F309M) in Complex with (amino(phenyl)methyl)phosphonic Acid
159. 4u75: Hsmetap (F309M) in Complex with Methionine
160. 4u76: Hsmetap (F309M) Holo Form
161. 4u6z: HSMETAP(F309M) in Complex with 1-amino-2-propylpentyl)phosphonic Acid
162. 6lvh: Crystal Structure of Methionine Aminopeptidase from Pyrococcus Furiosus
163. 6lzb: Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with An-p2-5h-06
164. 6lzc: Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with Kv-p2-4h-05
165. 6m00: Crystal Structure of Methionine Aminopeptidase from Pyrococcus Furiosus