EC 3.4.14.5 - dipeptidyl- peptidase IV

3D structures of EC 3.4.14.5 - dipeptidyl-peptidase IV in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1j2e: Crystal Structure of Human Dipeptidyl Peptidase IV
2. 3oc0: Structure of Human Dpp-iv with Hts Hit (2s,3s,11bs)-3-butyl-9,10- Dimethoxy-1,3,4,6,7,11b-hexahydro-2h-pyrido[2,1-a]isoquinolin-2- Ylamine
3. 1n1m: Human Dipeptidyl Peptidase Iv/cd26 in Complex with an Inhibitor
4. 1nu6: Crystal Structure of Human Dipeptidyl Peptidase IV (dpp-iv)
5. 1nu8: Crystal Structure of Human Dipeptidyl Peptidase IV (dpp-iv) in Complex with Diprotin a (ili)
6. 3kwj: Strucutre of Human Dpp-iv with (2s,3s,11bs)-3-(3-fluoromethyl-phenyl)- 9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2h-pyrido[2,1-a]isoquinolin-2- Ylamine
7. 3kwf: Human Dpp-iv with Carmegliptin (s)-1-((2s,3s,11bs)-2-amino- 9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2h-pyrido[2,1- A]isoquinolin-3-yl)-4-fluoromethyl-pyrrolidin-2-one
8. 1orv: Crystal Structure of Porcine Dipeptidyl Peptidase IV (cd26)
9. 1orw: Crystal Structure of Porcine Dipeptidyl Peptidase IV (cd26) in Complex with a Peptidomimetic Inhibitor
10. 1pfq: Crystal Structure of Human Apo Dipeptidyl Peptidase IV / Cd26
11. 3hac: The Structure of Dpp-4 in Complex with Piperidine Fused Imidazopyridine 34
12. 3hab: The Structure of Dpp4 in Complex with Piperidine Fused Benzimidazole 25
13. 3h0c: Crystal Structure of Human Dipeptidyl Peptidase IV (cd26) in Complex with a Reversed Amide Inhibitor
14. 1r9m: Crystal Structure of Human Dipeptidyl Peptidase IV at 2.1 Ang. Resolution.
15. 1r9n: Crystal Structure of Human Dipeptidyl Peptidase IV in Complex with a Decapeptide (tnpy) at 2.3 Ang. Resolution
16. 1rwq: Human Dipeptidyl Peptidase IV in Complex with 5-aminomethyl- 6-(2,4-dichloro-phenyl)-2-(3,5-dimethoxy-phenyl)-pyrimidin- 4-ylamine
17. 3g0g: Crystal Structure of Dipeptidyl Peptidase IV in Complex with a Pyrimidinone Inhibitor 3
18. 3g0d: Crystal Structure of Dipeptidyl Peptidase IV in Complex with a Pyrimidinedione Inhibitor 2
19. 3g0c: Crystal Structure of Dipeptidyl Peptidase IV in Complex with a Pyrimidinedione Inhibitor 1
20. 3g0b: Crystal Structure of Dipeptidyl Peptidase IV in Complex with Tak-322
21. 3f8s: Crystal Structure of Dipeptidyl Peptidase IV in Complex with Inhibitor
22. 3eio: Crystal Structure Analysis of Dppiv Inhibitor
23. 1tk3: Crystal Structure of Human Apo Dipeptidyl Peptidase Iv/cd26
24. 1tkr: Human Dipeptidyl Peptidase Iv/cd26 Inhibited with Diisopropyl Fluorophosphate
25. 1u8e: Human Dipeptidyl Peptidase Iv/cd26 Mutant Y547F
26. 3d4l: Human Dipeptidyl Peptidase Iv/cd26 in Complex with a Novel Inhibitor
27. 3ccc: Crystal Structure of Human Dpp4 in Complex with a Benzimidazole Derivative
28. 3ccb: Crystal Structure of Human Dpp4 in Complex with a Benzimidazole Derivative
29. 3c45: Human Dipeptidyl Peptidase Iv/cd26 in Complex with a Fluoroolefin Inhibitor
30. 3c43: Human Dipeptidyl Peptidase Iv/cd26 in Complex with a Flouroolefin Inhibitor
31. 3bjm: Crystal Structure of Human Dpp-iv in Complex with (1s,3s, 5s)-2-[(2s)- 2-amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1- Yl)acetyl]-2- Azabicyclo[3.1.0]hexane-3-carbonitrile (cas), (1s,3s,5s)-2-((2s)-2- Amino-2-(3-hydroxyadamantan-1- Yl)acetyl)-2-azabicyclo[3.1.0]hexane- 3-carbonitrile (iupac), or Bms-477118
32. 1w1i: Crystal Structure of Dipeptidyl Peptidase IV (dppiv or Cd26) in Complex with Adenosine Deaminase
33. 1wcy: Crystal Structure of Human Dipeptidyl Peptidase IV (dppiv) Complex with Diprotin a
34. 1x70: Human Dipeptidyl Peptidase IV in Complex with a Beta Amino Acid Inhibitor
35. 2aj8: Porcine Dipeptidyl Peptidase IV (cd26) in Complex with 7- Benzyl-1,3-dimethyl-8-piperazin-1-yl-3,7-dihydro-purine-2, 6-dione (bdpx)
36. 2ajb: Porcine Dipeptidyl Peptidase IV (cd26) in Complex with The Tripeptide Tert-butyl-gly-l-pro-l-ile (tbu-gpi)
37. 2ajc: Porcine Dipeptidyl Peptidase IV (cd26) in Complex with 4-(2- Aminoethyl)-benzene Sulphonyl Fluoride (aebsf)
38. 2ajd: Porcine Dipeptidyl Peptidase IV (cd26) in Complex with L- Pro-boro-l-pro (boropro)
39. 2ajl: X-ray Structure of Novel Biaryl-based Dipeptidyl Peptidase IV Inhibitor
40. 2bgn: Hiv-1 Tat Protein Derived N-terminal Nonapeptide Trp2-tat (1-9) Bound to The Active Site of Dipeptidyl Peptidase IV (cd26)
41. 2bgr: Crystal Structure of Hiv-1 Tat Derived Nonapeptides Tat(1-9) Bound to The Active Site of Dipeptidyl Peptidase IV (cd26)
42. 2rip: Structure of Dppiv in Complex with an Inhibitor
43. 2rgu: Crystal Structure of Complex of Human Dpp4 and Inhibitor
44. 2bua: Crystal Structure of Porcine Dipeptidyl Peptidase IV (cd26) in Complex with a Low Molecular Weight Inhibitor.
45. 2bub: Crystal Structure of Human Dipeptidyl Peptidase IV (cd26) in Complex with a Reversed Amide Inhibitor
46. 2buc: Crystal Structure of Porcine Dipeptidyl Peptidase IV (cd26) in Complex with a Tetrahydroisoquinoline Inhibitor
47. 2qtb: Human Dipeptidyl Peptidase Iv/cd26 in Complex with a 4-aryl Cyclohexylalanine Inhibitor
48. 2qt9: Human Dipeptidyl Peptidase Iv/cd26 in Complex with a 4-aryl Cyclohexylalanine Inhibitor
49. 2qoe: Human Dipeptidyl Peptidase IV in Complex with a Triazolopiperazine-based Beta Amino Acid Inhibitor
50. 2qky: Complex Structure of Dipeptidyl Peptidase IV and a Oxadiazolyl Ketone
51. 2qjr: Dipepdyl Peptidase IV in Complex with Inhibitor Pzf
52. 2p8s: Human Dipeptidyl Peptidase Iv/cd26 in Complex with a Cyclohexalamine Inhibitor
53. 2oqv: Human Dipeptidyl Peptidase IV (dpp4) with Piperidine- Constrained Phenethylamine
54. 2oqi: Human Dipeptidyl Peptidase IV (dpp4) with Piperidinone- Constrained Phenethylamine
55. 2oph: Human Dipeptidyl Peptidase IV in Complex with an Alpha Amino Acid Inhibitor
56. 2onc: Crystal Structure of Human Dpp-4
57. 2ole: Crystal Structure of Human Dipeptidyl Peptidase IV (dppiv) Complex with Cyclic Hydrazine Derivatives
58. 2ogz: Crystal Structure of Dpp-iv Complexed with Lilly Aryl Ketone Inhibitor
59. 2oag: Crystal Structure of Human Dipeptidyl Peptidase IV (dppiv) with Pyrrolidine-constrained Phenethylamine 29g
60. 2oae: Crystal Structure of Rat Dipeptidyl Peptidase (dppiv) with Thiazole-based Peptide Mimetic #31
61. 6b1o: The Structure of Dpp4 in Complex with Vildagliptin Analog
62. 6b1e: The Structure of Dpp4 in Complex with Vildagliptin
63. 2ecf: Crystal Structure of Dipeptidyl Aminopeptidase IV from Stenotrophomonas Maltophilia
64. 5zid: Crystal Structure of Human Dpp-iv in Complex with Hl2
65. 2fjp: Human Dipeptidyl Peptidase Iv/cd26 in Complex with an Inhibitor
66. 2g5p: Crystal Structure of Human Dipeptidyl Peptidase IV (dppiv) Complexed with Cyanopyrrolidine (c5-pro-pro) Inhibitor 21ac
67. 2g5t: Crystal Structure of Human Dipeptidyl Peptidase IV (dppiv) Complexed with Cyanopyrrolidine (c5-pro-pro) Inhibitor 21ag
68. 2g63: Crystal Structure of Human Dipeptidyl Peptidase IV (dppiv) Complexed with Cyanopyrrolidine (c5-pro-pro) Inhibitor 24b
69. 2gbf: Rat Dpp-iv with Alkynyl Cyanopyrrolidine #1
70. 2gbg: Rat Dpp-iv with Alkynyl Cyanopyrrolidine #2
71. 2gbi: Rat Dpp-iv with Xanthine Inhibitor 4
72. 5yp4: Crystal Structure of Dipeptidyl Peptidase IV (dpp Iv) with Lys-pro from Pseudoxanthomonas Mexicana Wo24
73. 5yp3: Crystal Structure of Dipeptidyl Peptidase IV (dpp Iv) with Ile-pro from Pseudoxanthomonas Mexicana
74. 5yp2: Crystal Structure of Dipeptidyl Peptidase IV (dpp Iv) with Dpp4 Inhibitor from Pseudoxanthomonas Mexicana Wo24
75. 5yp1: Crystal Structure of Dipeptidyl Peptidase IV (dpp Iv) from Pseudoxanthomonas Mexicana Wo24
76. 2hha: The Structure of Dpp4 in Complex with an Oxadiazole Inhibitor
77. 2i03: Crystal Structure of Human Dipeptidyl Peptidase 4 (dpp Iv) with Potent Alkynyl Cyanopyrrolidine (abt-279)
78. 2i3z: Rat Dpp-iv with Xanthine Mimetic Inhibitor #7
79. 2i78: Crystal Structure of Human Dipeptidyl Peptidase IV (dpp Iv) Complexed with Abt-341, a Cyclohexene-constrained Phenethylamine Inhibitor
80. 2iit: Human Dipeptidyl Peptidase 4 in Complex with a Diazepan-2- One Inhibitor
81. 2iiv: Human Dipeptidyl Peptidase 4 in Complex with a Diazepan-2- One Inhibitor
82. 2jid: Human Dipeptidyl Peptidase IV in Complex with 1-(3,4- Dimethoxy-phenyl)-3-m-tolyl-piperidine-4-ylamine
83. 6qzw: Dpp8 Bound to a Dipeptide (mp) from The N-terminus of Brca2
84. 6qzv: Dpp9 Bound to a Dipeptide (mp) from The N-terminus of Brca2
85. 3o95: Crystal Structure of Human Dpp4 Bound to Tak-100
86. 3o9v: Crystal Structure of Human Dpp4 Bound to Tak-986
87. 3q8w: A B-aminoacyl Containing Thiazolidine Derivative and Dppiv Complex
88. 3opm: Crystal Structure of Human Dpp4 Bound to Tak-294
89. 3sww: Crystal Structure of Human Dpp-iv in Complex with Sa-(+)-3- (aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyphenyl)- 2-methyl- 5h-pyrrolo[3,4-b]pyridin-7(6h)-one
90. 3sx4: Crystal Structure of Human Dpp-iv in Complex with Sa-(+)-3- (aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyphenyl)- 2-methyl- 5h-pyrrolo[3,4-b]pyridin-7(6h)-one
91. 3qbj: Crystal Structure of Dipeptidyl Peptidase IV in Complex with Inhibitor
92. 4a5s: Crystal Structure of Human Dpp4 in Complex with a Noval Heterocyclic Dpp4 Inhibitor
93. 3q0t: Crystal Structure of Human Dpp-iv in Complex Withsa-(+)- Methyl2-(3- (aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl- 7-oxo-5h-pyrrolo[3,4- B]pyridin-6(7h)-yl)acetate
94. 3vjm: Crystal Structure of Human Depiptidyl Peptidase IV (dpp-4) in Complex with a Prolylthiazolidine Inhibitor #1
95. 3vjk: Crystal Structure of Human Depiptidyl Peptidase IV (dpp-4) in Complex with Mp-513
96. 3vjl: Crystal Structure of Human Depiptidyl Peptidase IV (dpp-4) in Complex with a Prolylthiazolidine Inhibitor #2
97. 4ffv: Crystal Structure of Dipeptidyl Peptidase IV (dpp4, Dpp-iv, Cd26) in Complex with 11a19 Fab
98. 4ffw: Crystal Structure of Dipeptidyl Peptidase IV (dpp4, Dpp-iv, Cd26) in Complex with Fab + Sitagliptin
99. 4dsa: Crystal Structure of Dpp-iv with Compound C1
100. 4dsz: Crystal Structure of Dpp-iv with Compound C2
101. 4dtc: Crystal Structure of Dpp-iv with Compound C5
102. 4g1f: Crystal Structure of Human Dipeptidyl Peptidase IV in Complex with a Pyridopyrimidinedione Analogue
103. 6hp8: Crystal Structure of Dpp8 in Complex with Val-boropro
104. 3w2t: Crystal Structure of Human Depiptidyl Peptidase IV (dpp-4) in Complex with Vildagliptin
105. 4kr0: Complex Structure of Mers-cov Spike Rbd Bound to Cd26
106. 6eot: Dpp8 - Slrflyeg, Space Group 19
107. 6eos: Dpp8 - Apo, Space Group 19
108. 6eor: Dpp9 - 1g244
109. 6eoq: Dpp9 - Apo
110. 6eop: Dpp8 - Slrflyeg, Space Group 20
111. 6eoo: Dpp8 - Apo, Space Group 20
112. 4j3j: Crystal Structure of Dpp-iv with Compound C3
113. 4jh0: Crystal Structure of Dipeptidyl-peptidase 4 (cd26, Adenosine Deaminase Complexing Protein 2) (dpp-iv-wt) Complex with Bms-767778 Aka 2-(3- (aminomethyl)-4-(2,4- Dichlorophenyl)-2-methyl-5-oxo-5,7-dihydro-6h- Pyrrolo[3,4- B]pyridin-6-yl)-n,n-dimethylacetamide
114. 4l72: Crystal Structure of Mers-cov Complexed with Human Dpp4
115. 4lko: Crystal Structure of Human Dpp-iv in Complex with Bms-744891
116. 4n8d: Dpp4 Complexed with Syn-7aa
117. 4n8e: Dpp4 Complexed with Compound 12a
118. 5y7k: Crystal Structure of Human Dpp4 in Complex with Inhibitor1
119. 5y7j: Crystal Structure of Human Dpp4 in Complex with Inhibitor2
120. 5y7h: Crystal Structure of Human Dpp4 in Complex with Inhibitor3
121. 4pnz: Human Dipeptidyl Peptidase Iv/cd26 in Complex with The Long-acting Inhibitor Omarigliptin (mk-3102)
122. 4qzv: Bat-derived Coronavirus Hku4 Uses Mers-cov Receptor Human Cd26 for Cell Entry
123. 5vta: Co-crystal Structure of Dppiv with a Chemibody Inhibitor
124. 5t4h: Human Dpp4 in Complex with Ligand 34n
125. 5t4f: Human Dpp4 in Complex with Ligand 34p
126. 5t4e: Human Dpp4 in Complex with Ligand 19a
127. 5t4b: Human Dpp4 in Complex with a Ligand 34a
128. 5lls: Porcine Dipeptidyl Peptidase IV in Complex with 8-(3-aminopiperidin-1- Yl)-7-[(2-bromophenyl)methyl]-1,3-dimethyl-2,3,6,7-tetrahydro-1h- Purine-2,6-dione
129. 5kby: Crystal Structure of Dipeptidyl Peptidase IV in Complex with Syr-472
130. 5j3j: Crystal Structure of Human Dpp-iv in Complex with Hl1
131. 5ism: Human Dpp4 in Complex with a Novel 5,5,6-tricyclic Pyrrolidine Inhibitor
132. 5i7u: Human Dpp4 in Complex with a Novel Tricyclic Hetero-cycle Inhibitor
133. 4pv7: Cocrystal Structure of Dipeptidyl-peptidase 4 with an Indole Scaffold Inhibitor
134. 3wqh: Crystal Structure of Human Dpp-iv in Complex with Anagliptin
135. 6trw: Crystal Structure of Dpp8 in Complex with The Eil Peptide (slrflfegqriadnh)
136. 6trx: Crystal Structure of Dpp8 in Complex with 1g244
137. 6y0f: Structure of Human Fapalpha in Complex with Linagliptin
138. 6x6a: Cryo-em Structure of Nlrp1-dpp9 Complex
139. 6x6c: Cryo-em Structure of Nlrp1-dpp9-vbp Complex
140. 7jn7: Human Dpp9-card8 Complex
141. 7jkq: Human Dpp9-card8 Complex
142. 7a3f: Crystal Structure of Apo Dpp9
143. 7a3g: Crystal Structure of Dpp8 in Complex with a 4-oxo-b-lactam Based Inhibitor, 91
144. 7a3i: Crystal Structure of Dpp8 in Complex with a 4-oxo-b-lactam Based Inhibitor, Lmc375
145. 7a3j: Crystal Structure of Dpp8 in Complex with a 4-oxo-b-lactam Based Inhibitor, A272
146. 7a3l: Crystal Structure of Dpp8 in Complex with a 4-oxo-b-lactam Based Inhibitor, A241
147. 7ayq: Crystal Structure of Dpp8 in Complex with a 4-oxo-b-lactam Based Inhibitor, B114
148. 7ayr: Crystal Structure of Dpp8 in Complex with a 4-oxo-b-lactam Based Inhibitor, B115
149. 7a3k: Crystal Structure of Dpp8 in Complex with a B-lactam Based Inhibitor, A296.1
150. 7or4: Crystal Structure of Dpp8 in Complex with a 4-oxo-b-lactam Based Inhibitor, B142
151. 7oz7: Crystal Structure of Dpp8 in Complex with a 4-oxo-b-lactam Based Inhibitor, L84