EC 3.4.16.4 - serine- type D- Ala- D- Ala carboxypeptidase

3D structures of EC 3.4.16.4 - serine-type D-Ala-D-Ala carboxypeptidase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1cef: Cefotaxime Complexed with The Streptomyces R61 Dd-peptidase
2. 1ceg: Cephalothin Complexed with Dd-peptidase
3. 1es2: S96A Mutant of Streptomyces K15 Dd-transpeptidase
4. 1es3: C98A Mutant of Streptomyces K15 Dd-transpeptidase
5. 1es4: C98N Mutant of Streptomyces K15 Dd-transpeptidase
6. 1es5: S216A Mutant of Streptomyces K15 Dd-transpeptidase
7. 1esi: R248L Mutant of Streptomyces K15 Dd-transpeptidase
8. 1hd8: Crystal Structure of a Deacylation-defective Mutant of Penicillin-binding Protein 5 at 2.3 a Resolution
9. 1hvb: Crystal Structure of Streptomyces R61 Dd-peptidase Complexed with a Novel Cephalosporin Analog of Cell Wall Peptidoglycan
10. 1ikg: Michaelis Complex of Streptomyces R61 Dd-peptidase with a Specific Peptidoglycan Substrate Fragment
11. 1iki: Complex of Streptomyces R61 Dd-peptidase with The Products of a Specific Peptidoglycan Substrate Fragment
12. 1j9m: K38H Mutant of Streptomyces K15 Dd-transpeptidase
13. 3pte: The Refined Crystallographic Structure of a Dd-peptidase Penicillin-target Enzyme at 1.6 a Resolution
14. 1mpl: Crystal Structure of Phosphonate-inhibited D-ala-d-ala Peptidase Reveals an Analog of a Tetrahedral Transition State
15. 3mfd: The Structure of The Beta-lactamase Superfamily Domain of D-alanyl-d- Alanine Carboxypeptidase from Bacillus Subtilis
16. 1mwt: Structure of Penicillin G Acyl-penicillin Binding Protein 2a from Methicillin Resistant Staphylococcus Aureus Strain 27r at 2.45 a Resolution.
17. 3lo7: Crystal Structure of Pbpa from Mycobacterium Tuberculosis
18. 1nj4: Crystal Structure of a Deacylation-defective Mutant of Penicillin-binding Protein 5 at 1.9 a Resolution
19. 1nzo: The Crystal Structure of Wild Type Penicillin-binding Protein 5 from E. Coli
20. 1nzu: Wild-type Penicillin-binding Protein 5 from E. Coli Modified by Beta-mercaptoethanol
21. 3itb: Crystal Structure of Penicillin-binding Protein 6 (pbp6) from E. Coli in Complex with a Substrate Fragment
22. 3ita: Crystal Structure of Penicillin-binding Protein 6 (pbp6) from E. Coli in Acyl-enzyme Complex with Ampicillin
23. 3it9: Crystal Structure of Penicillin-binding Protein 6 (pbp6) from E. Coli in Apo State
24. 1pw1: Non-covalent Complex of Streptomyces R61 Dd-peptidase with a Highly Specific Penicillin
25. 1pw8: Covalent Acyl Enzyme Complex of The R61 Dd-peptidase with a Highly Specific Cephalosporin
26. 1pwc: Penicilloyl Acyl Enzyme Complex of The Streptomyces R61 Dd- Peptidase with Penicillin G
27. 1pwd: Covalent Acyl Enzyme Complex of The Streptomyces R61 Dd- Peptidase with Cephalosporin C
28. 1pwg: Covalent Penicilloyl Acyl Enzyme Complex of The Streptomyces R61 Dd-peptidase with a Highly Specific Penicillin
29. 3hun: Crystal Structure of Penicillin Binding Protein 4 from Staphylococcus Aureus Col in Complex with Ampicillin
30. 3hum: Crystal Structure of Penicillin Binding Protein 4 from Staphylococcus Aureus Col in Complex with Cefotaxime
31. 1scw: Toward Better Antibiotics: Crystal Structure of R61 Dd- Peptidase Inhibited by a Novel Monocyclic Phosphate Inhibitor
32. 1sde: Toward Better Antibiotics: Crystal Structure of D-ala-d-ala Peptidase Inhibited by a Novel Bicyclic Phosphate Inhibitor
33. 1sdn: Crystal Structure of a Deacylation-defective Mutant of Penicillin-binding Protein 5 Modified by Mercury
34. 1skf: Crystal Structure of The Streptomyces K15 Dd-transpeptidase
35. 3eqv: Crystal Structure of Penicillin-binding Protein 2 from Neisseria Gonorrhoeae Containing Four Mutations Associated with Penicillin Resistance
36. 3equ: Crystal Structure of Penicillin-binding Protein 2 from Neisseria Gonorrhoeae
37. 3bec: Crystal Structure of E. Coli Penicillin-binding Protein 5 in Complex with a Peptide-mimetic Cephalosporin
38. 3beb: Crystal Structure of E. Coli Penicillin-binding Protein 5 in Complex with a Peptide-mimetic Penicillin
39. 1w5d: Crystal Structure of PBP4A from Bacillus Subtilis
40. 1w79: Crystal Structure of The Dd-transpeptidase-carboxypeptidase from Actinomadura R39
41. 1w8q: Crystal Structure of The Dd-transpeptidase-carboxypeptidase from Actinomadura R39
42. 1w8y: Crystal Structure of The Nitrocefin Acyl-dd-peptidase from Actinomadura R39.
43. 3a3j: Crystal Structures of Penicillin Binding Protein 5 from Haemophilus Influenzae
44. 3a3i: Crystal Structure of Penicillin Binding Protein 4 (dacb) from Haemophilus Influenzae, Complexed with Ampicillin (aix)
45. 3a3f: Crystal Structure of Penicillin Binding Protein 4 (dacb) from Haemophilus Influenzae,complexed with Novel Beta- Lactam (fmz)
46. 3a3e: Crystal Structure of Penicillin Binding Protein 4 (dacb) from Haemophilus Influenzae, Complexed with Novel Beta- Lactam (cmv)
47. 3a3d: Crystal Structure of Penicillin Binding Protein 4 (dacb) from Haemophilus Influenzae
48. 1xp4: Crystal Structure of a Peptidoglycan Synthesis Regulatory Factor (pbp3) from Streptococcus Pneumoniae
49. 2xdm: Crystal Structure of a Complex between Actinomadura R39 Dd Peptidase and a Peptidoglycan Mimetic Boronate Inhibitor
50. 1yqs: Inhibition of The R61 Dd-peptidase by N-benzoyl-beta-sultam
51. 2wke: Crystal Structure of The Actinomadura R39 Dd-peptidase Inhibited by 6-beta-iodopenicillanate.
52. 1z6f: Crystal Structure of Penicillin-binding Protein 5 from E. Coli in Complex with a Boronic Acid Inhibitor
53. 2vgk: Crystal Structure of Actinomadura R39 Dd-peptidase Complexed with a Peptidoglycan-mimetic Cephalosporin
54. 2vgj: Crystal Structure of Actinomadura R39 Dd-peptidase Complexed with a Peptidoglycan-mimetic Cephalosporin
55. 2v2f: Crystal Structure of PBP1A from Drug-resistant Strain 5204 from Streptococcus Pneumoniae
56. 6yn0: Structure of E. Coli PBP1B with a Ftsn Peptide Activating Transglycosylase Activity
57. 6azi: 1.75 Angstrom Resolution Crystal Structure of D-alanyl-d-alanine Endopeptidase from Enterobacter Cloacae in Complex with Covalently Bound Boronic Acid
58. 6a6a: Vanyb in Complex with D-alanine
59. 5zhw: Vanyb in Complex with D-alanine-d-alanine
60. 5zhf: Structure of Vanyb Unbound
61. 2ex2: Crystal Structure of Penicillin Binding Protein 4 (dacb) from Escherichia Coli
62. 2ex6: Crystal Structure of Penicillin Binding Protein 4 (dacb) from Escherichia Coli, Complexed with Ampicillin
63. 2ex8: Crystal Structure of Penicillin Binding Protein 4 (dacb) from Escherichia Coli, Complexed with Penicillin-g
64. 2ex9: Crystal Structure of Penicillin Binding Protein 4 (dacb) from Escherichia Coli, Complexed with Penicillin-v
65. 2exa: Crystal Structure of Penicillin Binding Protein 4 (dacb) from Escherichia Coli, Complexed with Farom
66. 2exb: Crystal Structure of Penicillin Binding Protein 4 (dacb) from Escherichia Coli, Complexed with Flomox
67. 6r3x: Structure of Pseudomonas Aeruginosa Penicillin-binding Protein 3 (pbp3) in Complex with Piperacillin
68. 2j7v: Structure of Pbp-a
69. 2j8y: Structure of Pbp-a Acyl-enzyme Complex with Penicillin-g
70. 2j9o: Structure of Pbp-a, L158E Mutant
71. 2j9p: Crystal Structure of The Bacillus Subtilis PBP4A, and Its Complex with a Peptidoglycan Mimetic Peptide.
72. 2jbf: Structure of Pbp-a, L158E Mutant. Acyl-enzyme Complex with Penicillin-g.
73. 6syn: Crystal Structure of Y. Pestis Penicillin-binding Protein 3
74. 6y6z: Structure of Pseudomonas Aeruginosa Penicillin-binding Protein 3 (pbp3) in Complex with Compound 1
75. 6y6u: Structure of Pseudomonas Aeruginosa Penicillin-binding Protein 3 (pbp3) in Complex with Compound 6
76. 2xk1: Crystal Structure of a Complex between Actinomadura R39 Dd- Peptidase and a Boronate Inhibitor
77. 2xln: Crystal Structure of a Complex between Actinomadura R39 Dd-peptidase and a Boronate Inhibitor
78. 6r40: Apo Structure of R504C Mutant of Pseudomonas Aeruginosa Penicillin- Binding Protein 3 (pbp3)
79. 6r42: Structure of R504C Mutant of Pseudomonas Aeruginosa Penicillin-binding Protein 3 (pbp3) in Complex with Piperacillin
80. 6vot: Crystal Structure of Pseudomonas Aerugonisa Pbp3 Complexed to Gamma- Lactam Yu253434
81. 3mzd: Structure of Penicillin-binding Protein 5 from E. Coli: Cloxacillin Acyl-enzyme Complex
82. 3mze: Structure of Penicillin-binding Protein 5 from E.coli: Cefoxitin Acyl- Enzyme Complex
83. 3mzf: Structure of Penicillin-binding Protein 5 from E. Coli: Imipenem Acyl- Enzyme Complex
84. 6vbm: Crystal Structure of a S310A Mutant of Pbp2 from Neisseria Gonorrhoeae
85. 6vbl: Crystal Structure of The Transpeptidase Domain of Pbp2 from The Neisseria Gonorrhoeae Cephalosporin Decreased Susceptibility Strain 35/02
86. 6vbd: Crystal Structure of Transpeptidase Domain of Pbp2 from Neisseria Gonorrhoeae Cephalosporin-resistant Strain H041 Acylated by Ceftriaxone
87. 6vbc: Crystal Structure of Transpeptidase Domain of Pbp2 from Neisseria Gonorrhoeae Cephalosporin-resistant Strain H041
88. 2y4a: Unexpected Tricovalent Binding Mode of Boronic Acids within The Active Site of a Penicillin Binding Protein
89. 2y55: Unexpected Tricovalent Binding Mode of Boronic Acids within The Active Site of a Penicillin Binding Protein
90. 2y59: Unexpected Tricovalent Binding Mode of Boronic Acids within The Active Site of a Penicillin Binding Protein
91. 6vje: Penicillin-binding Protein in Complex with Antibiotic
92. 6un3: Crystal Structure of Pseudomonas Aeruginosa Pbp3 in Complex with Ticarcillin
93. 6un1: Crystal Structure of Pseudomonas Aeruginosa Pbp3 in Complex with Temocillin
94. 3v39: Bd3459, a Predatory Peptidoglycan Endopeptidase from Bdellovibrio Bacteriovorus
95. 3zvt: Unexpected Tricovalent Binding Mode of Boronic Acids within The Active Site of a Penicillin Binding Protein
96. 3zvw: Unexpected Tricovalent Binding Mode of Boronic Acids within The Active Site of a Penicillin Binding Protein
97. 6p56: Crystal Structure of The Transpeptidase Domain of a T498A Mutant of Pbp2 from Neisseria Gonorrhoeae
98. 6p55: Crystal Structure of Transpeptidase Domain of Pbp2 from Neisseria Gonorrhoeae Acylated by Cefixime
99. 6p54: Crystal Structure of Transpeptidase Domain of Pbp2 from Neisseria Gonorrhoeae Acylated by Ceftriaxone
100. 6p53: Crystal Structure of The Transpeptidase Domain of Pbp2 from Neisseria Gonorrhoeae in Apo Form
101. 6p52: Crystal Structure of Transpeptidase Domain of Pbp2 from Neisseria Gonorrhoeae with a Bound Phosphate at The Active Site
102. 6osu: Crystal Structure of The D-alanyl-d-alanine Carboxypeptidase Dacd from Francisella Tularensis
103. 6ntz: Crystal Structure of E. Coli Pbp5-meropenem
104. 4dki: Structural Insights into The Anti- Methicillin-resistant Staphylococcus Aureus (mrsa) Activity of Ceftobiprole
105. 3upn: Structure of Penicillin-binding Protein a from M. Tuberculosis: Imipenem Acyl-enzyme Complex
106. 3upo: Structure of Penicillin-binding Protein a from M. Tuberculosis: Penicillin G Acyl-enzyme Complex
107. 3upp: Structure of Penicillin-binding Protein a from M. Tuberculosis: Ceftrixaone Acyl-enzyme Complex
108. 6i1i: Crystal Structure of Tp Domain from Escherichia Coli Penicillin- Binding Protein 3 in Complex with Penicillin
109. 6i1e: Crystal Structure of Pseudomonas Aeruginosa Penicillin-binding Protein 3 in Complex with Amoxicillin
110. 6hzr: Apo Structure of Pseudomonas Aeruginosa Penicillin-binding Protein 3
111. 6hzq: Apo Structure of Tp Domain from Escherichia Coli Penicillin-binding Protein 3
112. 6hzj: Apo Structure of Tp Domain from Clinical Penicillin-resistant Mutant Neisseria Gonorrhoea Strain 6140 Penicillin-binding Protein 2 (pbp2)
113. 6hzi: Apo Structure of Tp Domain from Burkholderia Pseudomallei Penicillin- Binding Protein 3
114. 6hr9: Nitrocefin Acylation of Both Catalytic Serines of The Y409 Mutant of Penicillin-binding Protein 3 from P. Aeruginosa
115. 6hr6: Nitrocefin Acylation of Single Catalytic Serine of Penicillin-binding Protein 3 from P. Aeruginosa
116. 6hr4: Apo Form of Penicillin-binding Protein 3 from P. Aeruginosa
117. 3zcz: Crystal Structure of a Complex between Actinomadura R39 Dd- Peptidase and a Trifluoroketone Inhibitor
118. 6h5o: Crystal Structure of PBP2A from Mrsa in Complex with Piperacillin at Active Site.
119. 4ben: R39-imipenem Acyl-enzyme Crystal Structure
120. 4jid: 2.3 Angstrom Resolution Crystal Structure of D-alanyl-d-alanine Carboxypeptidase from Bacillus Anthracis.
121. 6g9s: Structural Basis for The Inhibition of E. Coli Pbp2
122. 6g9p: Structural Basis for The Inhibition of E. Coli Pbp2
123. 6g9f: Structural Basis for The Inhibition of E. Coli Pbp2
124. 6g5r: Structure of The UB2H Domain of E.coli PBP1B in Complex with Lpob
125. 6fzk: Nmr Structure of UB2H, Regulatory Domain of PBP1B from E. Coli
126. 3zfz: Crystal Structure of Ceftaroline ACYL-PBP2A from Mrsa with Non-covalently Bound Ceftaroline and Muramic Acid at Allosteric Site Obtained by Soaking
127. 3zg0: Crystal Structure of Ceftaroline ACYL-PBP2A from Mrsa with Non-covalently Bound Ceftaroline and Muramic Acid at Allosteric Site Obtained by Cocrystallization
128. 3zg5: Crystal Structure of PBP2A from Mrsa in Complex with Peptidoglycan Analogue at Allosteric
129. 4b4x: Crystal Structure of a Complex between Actinomadura R39 Dd- Peptidase and a Sulfonamide Boronate Inhibitor
130. 4b4z: Crystal Structure of a Complex between Actinomadura R39 Dd-peptidase and a Sulfonamide Boronate Inhibitor
131. 4bl2: Crystal Structure of PBP2A Clinical Mutant E150K from Mrsa
132. 4bl3: Crystal Structure of PBP2A Clinical Mutant N146K from Mrsa
133. 4cpk: Crystal Structure of PBP2A Double Clinical Mutant N146K- E150K from Mrsa
134. 4k91: Crystal Structure of Penicillin-binding Protein 5 (pbp5) from Pseudomonas Aeruginosa in Apo State
135. 4p0m: Crystal Structure of an Evolved Putative Penicillin-binding Protein Homolog, Rv2911, from Mycobacterium Tuberculosis
136. 4u3t: Crystal Structure of The Transpeptidase Domain of Neisseria Gonorrhoeae Penicillin-binding Protein 2 Derived from The Penicillin- Resistant Strain 6140
137. 5tr7: Crystal Structure of a Putative D-alanyl-d-alanine Carboxypeptidase from Vibrio Cholerae O1 Biovar Eltor Str. N16961
138. 5ksh: Crystal Structure of Penicillin-binding Protein 2 from Neisseria Gonorrhoeae Containing an A501T Mutation Associated with Cephalosporin Resistance
139. 5j8x: Crystal Structure of E. Coli Pbp5 with 2c
140. 5hnm: Crystal Structure of Vancomycin Resistance D,d-pentapeptidase Vany E175A Mutant from Vanb-type Resistance Cassette in Complex with Zn(ii)
141. 5fsr: Crystal Structure of Penicillin Binding Protein 6b from Escherichia Coli
142. 5cer: Bd0816 Predatory Endopeptidase from Bdellovibrio Bacteriovorus in Complex with Immunity Protein Bd3460
143. 5ced: Penicillin G Acylated Bd3459 Predatory Endopeptidase from Bdellovibrio Bacteriovorus in Complex with Immunity Protein Bd3460
144. 5cec: Bd3459 Predatory Endopeptidase from Bdellovibrio Bacteriovorus in Complex with Immunity Protein Bd3460
145. 5ceb: Bd3459 Predatory Endopeptidase from Bdellovibrio Bacteriovorus, K38M Form
146. 4cjn: Crystal Structure of PBP2A from Mrsa in Complex with Quinazolinone Ligand
147. 7kis: Crystal Structure of Pseudomonas Aeruginosa Pbp2 in Complex with Wck 5153
148. 7kit: Crystal Structure of Pseudomonas Aeruginosa Pbp3 in Complex with Wck 4234
149. 7kiv: Crystal Structure of Pseudomonas Aeruginosa Pbp3 in Complex with Avibactam
150. 7kiw: Crystal Structure of Pseudomonas Aeruginosa Pbp3 in Complex with Zidebactam
151. 7lc4: Crystal Structure of Pseudomonas Aeruginosa Pbp3 in Complex with Gamma-lactam Yu253911
152. 7jwl: Crystal Structure of Pseudomonas Aeruginosa Penicillin Binding Protein 3 (pae-pbp3) Bound to Etx0462
153. 7lq6: Cryoem Structure of Escherichia Coli PBP1B
154. 6xqv: Crystal Structure of The Catalytic Domain of Pbp2 S310A from Neisseria Gonorrhoeae in a Pre-acylation Complex with Ceftriaxone
155. 6xqx: Crystal Structure of The Catalytic Domain of Pbp2 S310A from Neisseria Gonorrhoeae with The H514A Mutation at Ph 7.5
156. 6xqy: Crystal Structure of The Catalytic Domain of Pbp2 S310A from Neisseria Gonorrhoeae at Ph 9.5
157. 6xqz: Crystal Structure of The Catalytic Domain of Pbp2 S310A from Neisseria Gonorrhoeae at Ph 7.5
158. 7onk: Crystal Structure of Pbp3 from P. Aeruginosa in Complex with Aic499
159. 7onn: Crystal Structure of Pbp3 Transpeptidase Domain from E. Coli in Complex with Aic499
160. 7ono: Crystal Structure of Pbp3 Transpeptidase Domain from E. Coli
161. 7onw: Crystal Structure of Pbp3 from E. Coli in Complex with Aic499
162. 7onx: Crystal Structure of Pbp3 from P. Aeruginosa
163. 7ony: Crystal Structure of Pbp3 from P. Aeruginosa
164. 7onz: Crystal Structure of Pbp3 from P. Aeruginosa
165. 7atm: Structure of P. Aeruginosa Pbp3 in Complex with a Phenyl Boronic Acid (compound 1)
166. 7ato: Structure of P. Aeruginosa Pbp3 in Complex with an Aryl Boronic Acid (compound 2)
167. 7atw: Structure of P. Aeruginosa Pbp3 in Complex with a Benzoxaborole (compound 3)
168. 7atx: Structure of P. Aeruginosa Pbp3 in Complex with a Benzoxaborole (compound 4)
169. 7au0: Structure of P. Aeruginosa Pbp3 in Complex with a Benzoxaborole (compound 7)
170. 7au1: Structure of P. Aeruginosa Pbp3 in Complex with a Benzoxaborole (compound 12)
171. 7au8: Structure of P. Aeruginosa Pbp3 in Complex with a Benzoxaborole (compound 13)
172. 7au9: Structure of P. Aeruginosa Pbp3 in Complex with a Benzoxaborole (compound 14)
173. 7aub: Structure of P. Aeruginosa Pbp3 in Complex with a Benzoxaborole (compound 15)
174. 7auh: Structure of P. Aeruginosa Pbp3 in Complex with Vaborbactam
175. 7ly1: Crystal Structure of Pseudomonas Aeruginosa Pbp3 in Complex with Vaborbactam