EC 3.6.5.2 - GTP phosphohydrolase (cell- regulating) (small monomeric GTPase)

3D structures of EC 3.6.5.2 - small monomeric GTPase in Protein Data Bank

updated: 3 March 2021, 5:15

1. 1e0a: Cdc42 Complexed with The Gtpase Binding Domain of P21 Activated Kinase
2. 3mjh: Crystal Structure of Human RAB5A in Complex with The C2H2 Zinc Finger of Eea1
3. 1ryf: Alternative Splicing of Rac1 Generates RAC1B, a Self- Activating Gtpase
4. 1ryh: Alternative Splicing of Rac1 Generates RAC1B, a Self- Activating Gtpase
5. 3def: Crystal Structure of Toc33 from Arabidopsis Thaliana, Dimerization Deficient Mutant R130A
6. 3ddc: Crystal Structure of NORE1A in Complex with Ras
7. 3bfk: Crystal Structure of Plasmodium Falciparum RAB11A in Complex with Gdp
8. 3bc1: Crystal Structure of The Complex RAB27A-SLP2A
9. 2x1v: Crystal Structure of The Activating H-ras I163F Mutant in Costello Syndrome, Bound to Mg-gdp
10. 6v6v: Crystal Structure of Oncogenic Rhoa Mutant G14V Complexed with Gdp
11. 6v6u: Crystal Structure of Rhoa-gdp with Novel Switch I Conformation
12. 7acq: Crystal Structure of Inactive Kras G12D (gdp) in Complex with The Soaked Dimeric Inhibitor Bi-5747
13. 7ach: Crystal Structure of Active Kras G12D (gppcp) in Complex with The Soaked Dimeric Inhibitor Bi-5747
14. 7acf: Crystal Structure of Crystal Form 2 of an Active Kras G12D (gppcp) Dimer in Complex with Bi-5747
15. 7aca: Crystal Structure of an Active Kras G12D (gppcp) Dimer in Complex with Bi-5747
16. 2atx: Crystal Structure of The Tc10 Gppnhp Complex
17. 2bmd: High Resolution Structure of Gdp-bound Human RAB4A
18. 2bme: High Resolution Structure of Gppnhp-bound Human RAB4A
19. 2quz: Crystal Structure of The Activating H-RASK117R Mutant in Costello Syndrome, Bound to Mg-gdp
20. 2c5l: Structure of Plc Epsilon Ras Association Domain with Hras
21. 2dpx: Crystal Structure of Human Rad Gtpase
22. 2ee4: Solution Structure of The Rhogap Domain from Human Rho Gtpase Activating Protein 5 Variant
23. 2ee5: Solution Structure of The N-teruminus Extended Rhogap Domain from Human Rho Gtpase Activating Protein 5 Variant
24. 2f9l: 3d Structure of Inactive Human RAB11B Gtpase
25. 2f9m: 3d Structure of Active Human RAB11B Gtpase
26. 2gzd: Crystal Structure of Rab11 in Complex with Rab11-fip2
27. 2gzh: Crystal Structure of Rab11 in Complex with Rab11-family Interacting Protein 2
28. 5ymx: Myxococcus Xanthus Mgla in Gdp Bound Conformation
29. 2iey: Crystal Structure of Mouse RAB27B Bound to Gdp in Hexagonal Space Group
30. 2iez: Crystal Structure of Mouse RAB27B Bound to Gdp in Monoclinic Space Group
31. 2if0: Crystal Structure of Mouse RAB27B Bound to Gdp in Monoclinic Space Group
32. 2j1l: Crystal Structure of Human Rho-related Gtp-binding Protein Rhod
33. 6x1g: Crystal Structure of a Gef Domain from The Orientia Tsutsugamushi Protein Otdub in Complex with Rac1
34. 6v6m: Crystal Structure of an Inactive State of Gmppnp-bound Rhoa
35. 6tgc: Cryoem Structure of The Ternary Dock2-elmo1-rac1 Complex
36. 6kx3: Crystal Structure of Rhoa Protein with Covalent Inhibitor Dc-rhoin
37. 6kx2: Crystal Structure of Gdp Bound Rhoa Protein
38. 3msx: Crystal Structure of Rhoa.gdp.mgf3 in Complex with Gap Domain of Arhgap20
39. 6siu: Crystal Structure of Ibpafic2 Covalently Tethered to Cdc42
40. 3t12: Mgla in Complex with Mglb in Transition State
41. 3t1o: Mgla Bound to Gdp
42. 3t1q: Mgla Bound to Gppnhp in Complex with Mglb
43. 3t1t: Mgla Bound to Gdp in P1 Tetrameric Arrangement
44. 3t1v: Mgla Bound to Gdp in P2(1) Tetrameric Arrangement
45. 6sup: Crystal Structure of Tcdb2-tccc3-cdc42
46. 4dxa: Co-crystal Structure of Rap1 in Complex with Krit1
47. 5qu9: Pandda Analysis Group Deposition of Ground-state Model of Kalirin/rac1 Screened against a Customized Urea Fragment Library by X-ray Crystallography at The Xchem Facility of Diamond Light Source Beamline I04-1
48. 4epr: Crystal Structure of Kras-gdp (G12D)
49. 4ept: Discovery of Small Molecules That Bind to K-ras and Inhibit Sos- Mediated Activation
50. 4epv: Discovery of Small Molecules That Bind to K-ras and Inhibit Sos- Mediated Activation
51. 4epw: Discovery of Small Molecules That Bind to K-ras and Inhibit Sos- Mediated Activation
52. 4epx: Discovery of Small Molecules That Bind to K-ras and Inhibit Sos- Mediated Activation
53. 4epy: Discovery of Small Molecules That Bind to K-ras and Inhibit Sos- Mediated Activation
54. 6izw: Myxococcus Xanthus Mgla Bound to Gtp-gamma-s and Mglb
55. 4bas: Structure of The Arl6 Bbs3 Small Gtpase from Trypanosoma Brucei with Bound Nucleotide Analogue Gppnp
56. 4dvg: Crystal Structure of E. Histolytica Formin1 Bound to Ehrho1-gtpgammas
57. 4gzl: Crystal Structure of Rac1 Q61L Mutant
58. 4gzm: Crystal Structure of Rac1 F28L Mutant
59. 4iru: Crystal Structure of Lepb Gap Core in a Transition State Mimetic Complex with RAB1A and Alf3
60. 6e6p: Hras G13D Bound to Gppnhp (HA,B,C13GNP)
61. 4cym: Complex of Human Varp-ankrd1 with Rab32-gppcp
62. 4d0l: Phosphatidylinositol 4-kinase III Beta-pik93 in a Complex with RAB11A-GTP Gammas
63. 4d0m: Phosphatidylinositol 4-kinase III Beta in a Complex with RAB11A-GTP- Gamma-s and The Rab-binding Domain of Fip3
64. 4d0n: Akap13 (akap-lbc) Rhogef Domain in Complex with Rhoa
65. 4l9s: Crystal Structure of H-ras G12C, Gdp-bound
66. 4l9w: Crystal Structure of H-ras G12C, Gmppnp-bound
67. 4m9q: Crystal Structure of C-terminally Truncated ARL13B from Chlamydomonas Rheinhardtii Bound to Gppnhp
68. 4mit: Crystal Structure of E. Histolytica Racc Bound to The Ehpak4 Pbd
69. 4nmm: Crystal Structure of a G12C Oncogenic Variant of Human Kras Bound to a Novel Gdp Competitive Covalent Inhibitor
70. 4obe: Crystal Structure of Gdp-bound Human Kras
71. 4ojk: Structure of The Cgmp Dependent Protein Kinase II and RAB11B Complex
72. 4pzy: Second-site Screening of K-ras in The Presence of Covalently Attached First-site Ligands
73. 4pzz: Second-site Screening of K-ras in The Presence of Covalently Attached First-site Ligands
74. 4q01: Second-site Screening of K-ras in The Presence of Covalently Attached First-site Ligands
75. 4q02: Second-site Screening of K-ras in The Presence of Covalently Attached First-site Ligands
76. 4q03: Second-site Screening of K-ras in The Presence of Covalently Attached First-site Ligands
77. 5wds: Choanoflagellate Salpingoeca Rosetta Ras with Gdp Bound
78. 5wdr: Choanoflagellate Salpingoeca Rosetta Ras with Gmp-pnp
79. 5wdq: H-ras Mutant L120A Bound to Gmp-pnp at 100k
80. 5wdp: H-ras Mutant L120A Bound to Gmp-pnp at 277k
81. 5wdo: H-ras Bound to Gmp-pnp at 277k
82. 6tkz: Crystal Structure of The Dhr2 Domain of Dock10 in Complex with Cdc42
83. 6tky: Crystal Structure of The Dhr2 Domain of Dock10 in Complex with Cdc42
84. 4ql3: Crystal Structure of a Gdp-bound G12R Oncogenic Mutant of Human Gtpase Kras
85. 4xvq: H-ras Y137E
86. 4xvr: H-ras Y137F
87. 6xgu: Crystal Structure of KRAS-Q61R (gmppnp-bound) in Complex with Ras- Binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf
88. 6xgv: Crystal Structure of KRAS-G13D (gmppnp-bound) in Complex with Ras- Binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf
89. 6xha: Crystal Structure of KRAS-G12V (gmppnp-bound) in Complex with Ras- Binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf
90. 6xi7: Crystal Structure of Wild-type Kras (gmppnp-bound) in Complex with Ras-binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf (crystal Form I)