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enzyme (lysozyme)

 
Enzymes
  Enzyme classes:
  EC 1: Oxidoreductases
  EC 2: Transferases
  EC 3: Hydrolases
    EC 3.1
    EC 3.2
    EC 3.3
    EC 3.4
    EC 3.5
    EC 3.6
      EC 3.6.1
      EC 3.6.2
      EC 3.6.3
      EC 3.6.4
      EC 3.6.5
        EC 3.6.5.1
        EC 3.6.5.2
        EC 3.6.5.3
        EC 3.6.5.4
        EC 3.6.5.5
        EC 3.6.5.6
    EC 3.7
    EC 3.8
    EC 3.9
    EC 3.10
    EC 3.11
    EC 3.12
    EC 3.13
  EC 4: Lyases
  EC 5: Isomerases
  EC 6: Ligases
  General information:
  Catalytic mechanism
  Enzyme kinetics
  Inhibitors
  Enzymes in industry

EC 3.6.5.2 - GTP phosphohydrolase (cell- regulating) (small monomeric GTPase)



3D structures of EC 3.6.5.2 - small monomeric GTPase in Protein Data Bank

updated: 6 January 2022, 2:15

In total: 119 PDB structures of EC 3.6.5.2 - small monomeric GTPase:
  1. 1e0a: Cdc42 Complexed with The Gtpase Binding Domain of P21 Activated Kinase
  2. 3mjh: Crystal Structure of Human RAB5A in Complex with The C2H2 Zinc Finger of Eea1
  3. 1ryf: Alternative Splicing of Rac1 Generates RAC1B, a Self- Activating Gtpase
  4. 1ryh: Alternative Splicing of Rac1 Generates RAC1B, a Self- Activating Gtpase
  5. 3def: Crystal Structure of Toc33 from Arabidopsis Thaliana, Dimerization Deficient Mutant R130A
  6. 3ddc: Crystal Structure of NORE1A in Complex with Ras
  7. 3bfk: Crystal Structure of Plasmodium Falciparum RAB11A in Complex with Gdp
  8. 3bc1: Crystal Structure of The Complex RAB27A-SLP2A
  9. 2x1v: Crystal Structure of The Activating H-ras I163F Mutant in Costello Syndrome, Bound to Mg-gdp
  10. 6v6v: Crystal Structure of Oncogenic Rhoa Mutant G14V Complexed with Gdp
  11. 6v6u: Crystal Structure of Rhoa-gdp with Novel Switch I Conformation
  12. 7acq: Crystal Structure of Inactive Kras G12D (gdp) in Complex with The Soaked Dimeric Inhibitor Bi-5747
  13. 7ach: Crystal Structure of Active Kras G12D (gppcp) in Complex with The Soaked Dimeric Inhibitor Bi-5747
  14. 7acf: Crystal Structure of Crystal Form 2 of an Active Kras G12D (gppcp) Dimer in Complex with Bi-5747
  15. 7aca: Crystal Structure of an Active Kras G12D (gppcp) Dimer in Complex with Bi-5747
  16. 2atx: Crystal Structure of The Tc10 Gppnhp Complex
  17. 2bmd: High Resolution Structure of Gdp-bound Human RAB4A
  18. 2bme: High Resolution Structure of Gppnhp-bound Human RAB4A
  19. 2quz: Crystal Structure of The Activating H-RASK117R Mutant in Costello Syndrome, Bound to Mg-gdp
  20. 2c5l: Structure of Plc Epsilon Ras Association Domain with Hras
  21. 2dpx: Crystal Structure of Human Rad Gtpase
  22. 2ee4: Solution Structure of The Rhogap Domain from Human Rho Gtpase Activating Protein 5 Variant
  23. 2ee5: Solution Structure of The N-teruminus Extended Rhogap Domain from Human Rho Gtpase Activating Protein 5 Variant
  24. 2f9l: 3d Structure of Inactive Human RAB11B Gtpase
  25. 2f9m: 3d Structure of Active Human RAB11B Gtpase
  26. 2gzd: Crystal Structure of Rab11 in Complex with Rab11-fip2
  27. 2gzh: Crystal Structure of Rab11 in Complex with Rab11-family Interacting Protein 2
  28. 5ymx: Myxococcus Xanthus Mgla in Gdp Bound Conformation
  29. 2iey: Crystal Structure of Mouse RAB27B Bound to Gdp in Hexagonal Space Group
  30. 2iez: Crystal Structure of Mouse RAB27B Bound to Gdp in Monoclinic Space Group
  31. 2if0: Crystal Structure of Mouse RAB27B Bound to Gdp in Monoclinic Space Group
  32. 2j1l: Crystal Structure of Human Rho-related Gtp-binding Protein Rhod
  33. 6x1g: Crystal Structure of a Gef Domain from The Orientia Tsutsugamushi Protein Otdub in Complex with Rac1
  34. 6v6m: Crystal Structure of an Inactive State of Gmppnp-bound Rhoa
  35. 6tgc: Cryoem Structure of The Ternary Dock2-elmo1-rac1 Complex
  36. 6kx3: Crystal Structure of Rhoa Protein with Covalent Inhibitor Dc-rhoin
  37. 6kx2: Crystal Structure of Gdp Bound Rhoa Protein
  38. 3msx: Crystal Structure of Rhoa.gdp.mgf3 in Complex with Gap Domain of Arhgap20
  39. 6siu: Crystal Structure of Ibpafic2 Covalently Tethered to Cdc42
  40. 3t12: Mgla in Complex with Mglb in Transition State
  41. 3t1o: Mgla Bound to Gdp
  42. 3t1q: Mgla Bound to Gppnhp in Complex with Mglb
  43. 3t1t: Mgla Bound to Gdp in P1 Tetrameric Arrangement
  44. 3t1v: Mgla Bound to Gdp in P2(1) Tetrameric Arrangement
  45. 6sup: Crystal Structure of Tcdb2-tccc3-cdc42
  46. 4dxa: Co-crystal Structure of Rap1 in Complex with Krit1
  47. 5qu9: Pandda Analysis Group Deposition of Ground-state Model of Kalirin/rac1 Screened against a Customized Urea Fragment Library by X-ray Crystallography at The Xchem Facility of Diamond Light Source Beamline I04-1
  48. 4epr: Crystal Structure of Kras-gdp (G12D)
  49. 4ept: Discovery of Small Molecules That Bind to K-ras and Inhibit Sos- Mediated Activation
  50. 4epv: Discovery of Small Molecules That Bind to K-ras and Inhibit Sos- Mediated Activation
  51. 4epw: Discovery of Small Molecules That Bind to K-ras and Inhibit Sos- Mediated Activation
  52. 4epx: Discovery of Small Molecules That Bind to K-ras and Inhibit Sos- Mediated Activation
  53. 4epy: Discovery of Small Molecules That Bind to K-ras and Inhibit Sos- Mediated Activation
  54. 6izw: Myxococcus Xanthus Mgla Bound to Gtp-gamma-s and Mglb
  55. 4bas: Structure of The Arl6 Bbs3 Small Gtpase from Trypanosoma Brucei with Bound Nucleotide Analogue Gppnp
  56. 4dvg: Crystal Structure of E. Histolytica Formin1 Bound to Ehrho1-gtpgammas
  57. 4gzl: Crystal Structure of Rac1 Q61L Mutant
  58. 4gzm: Crystal Structure of Rac1 F28L Mutant
  59. 4iru: Crystal Structure of Lepb Gap Core in a Transition State Mimetic Complex with RAB1A and Alf3
  60. 6e6p: Hras G13D Bound to Gppnhp (HA,B,C13GNP)
  61. 4cym: Complex of Human Varp-ankrd1 with Rab32-gppcp
  62. 4d0l: Phosphatidylinositol 4-kinase III Beta-pik93 in a Complex with RAB11A-GTP Gammas
  63. 4d0m: Phosphatidylinositol 4-kinase III Beta in a Complex with RAB11A-GTP- Gamma-s and The Rab-binding Domain of Fip3
  64. 4d0n: Akap13 (akap-lbc) Rhogef Domain in Complex with Rhoa
  65. 4l9s: Crystal Structure of H-ras G12C, Gdp-bound
  66. 4l9w: Crystal Structure of H-ras G12C, Gmppnp-bound
  67. 4m9q: Crystal Structure of C-terminally Truncated ARL13B from Chlamydomonas Rheinhardtii Bound to Gppnhp
  68. 4mit: Crystal Structure of E. Histolytica Racc Bound to The Ehpak4 Pbd
  69. 4nmm: Crystal Structure of a G12C Oncogenic Variant of Human Kras Bound to a Novel Gdp Competitive Covalent Inhibitor
  70. 4obe: Crystal Structure of Gdp-bound Human Kras
  71. 4ojk: Structure of The Cgmp Dependent Protein Kinase II and RAB11B Complex
  72. 4pzy: Second-site Screening of K-ras in The Presence of Covalently Attached First-site Ligands
  73. 4pzz: Second-site Screening of K-ras in The Presence of Covalently Attached First-site Ligands
  74. 4q01: Second-site Screening of K-ras in The Presence of Covalently Attached First-site Ligands
  75. 4q02: Second-site Screening of K-ras in The Presence of Covalently Attached First-site Ligands
  76. 4q03: Second-site Screening of K-ras in The Presence of Covalently Attached First-site Ligands
  77. 5wds: Choanoflagellate Salpingoeca Rosetta Ras with Gdp Bound
  78. 5wdr: Choanoflagellate Salpingoeca Rosetta Ras with Gmp-pnp
  79. 5wdq: H-ras Mutant L120A Bound to Gmp-pnp at 100k
  80. 5wdp: H-ras Mutant L120A Bound to Gmp-pnp at 277k
  81. 5wdo: H-ras Bound to Gmp-pnp at 277k
  82. 6tkz: Crystal Structure of The Dhr2 Domain of Dock10 in Complex with Cdc42
  83. 6tky: Crystal Structure of The Dhr2 Domain of Dock10 in Complex with Cdc42
  84. 4ql3: Crystal Structure of a Gdp-bound G12R Oncogenic Mutant of Human Gtpase Kras
  85. 4xvq: H-ras Y137E
  86. 4xvr: H-ras Y137F
  87. 6xgu: Crystal Structure of KRAS-Q61R (gmppnp-bound) in Complex with Ras- Binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf
  88. 6xgv: Crystal Structure of KRAS-G13D (gmppnp-bound) in Complex with Ras- Binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf
  89. 6xha: Crystal Structure of KRAS-G12V (gmppnp-bound) in Complex with Ras- Binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf
  90. 6xi7: Crystal Structure of Wild-type Kras (gmppnp-bound) in Complex with Ras-binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf (crystal Form I)
  91. 6whe: Structure of Phosphomimetic RAB8A Gtpase (T72E) in The Gtp-bound State
  92. 7l0f: Monobody 12vc3 Bound to Hras(wt)
  93. 7l0g: Monobody 12vc1 Bound to HRAS(G12C)
  94. 7kfz: Structure of a Ternary KRAS(G13D)-SOS Complex
  95. 7eyx: Crystal Structure of Mg-free KRAS-G12D Bound to Gdp
  96. 7f0w: Crystal Structure of KRAS-G12D Bound to Gdp with Switch 1 Open Conformation
  97. 7lgi: The Haddock Model of Gdp Kras in Complex with Promazine Using Chemical Shift Perturbations and Intermolecular Noes
  98. 7dph: H-ras Q61H in Complex with Gppnhp (state 1) after Structural Transition by Humidity Control
  99. 7dpj: H-ras Q61L in Complex with Gppnhp (state 1) after Structural Transition by Humidity Control
  100. 7lc2: Crystal Structure of KRAS4B-Q61R (gmppnp-bound) in Complex with The Ras-binding Domain (rbd) of Sin1
  101. 7dpa: Cryo-em Structure of The Human Elmo1-dock5-rac1 Complex
  102. 7lc1: Crystal Structure of KRAS4B (gmppnp-bound) in Complex with The Rbd-ph Domains of Sin1
  103. 7s0y: Structures of Tcdb in Complex with Cdc42
  104. 7nqc: Calmodulin Extracts The Ras Family Protein Rala from Lipid Bilayers by Engagement with Two Membrane Targeting Motifs
  105. 7rov: Kras G12D Mutant in Complex with Gmppcp and Cyclic Peptide Mp-9903
  106. 7a1w: KRASG12C Gdp Form in Complex with Cpd3
  107. 7a1x: KRASG12C Gdp Form in Complex with Cpd1
  108. 7a1y: KRASG12C Gdp Form in Complex with Cpd2
  109. 7a47: KRASG12C Gdp Form in Complex with Cpd4
  110. 7kmr: Crystal Structure Analysis of Human Kras Mutant
  111. 7rpz: Kras G12D in Complex with Mrtx-1133
  112. 7rt1: Crystal Structure of Kras G12D with Compound 15 (4-(4-[(1r,5s)-3,8- Diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2s)-1-methylpyrrolidin- 2-yl]methoxy}pyrido[4,3-d]pyrimidin-7-yl)naphthalen-2-ol) Bound
  113. 7rt2: Crystal Structure of Kras G12D with Compound 25 (4-(4-[(1r,5s)-3,8- Diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2r,4r,7as)-2- Fluorotetrahydro-1h-pyrrolizin-7a(5h)-yl]methoxy}pyrido[4,3- D]pyrimidin-7-yl)naphthalen-2-ol) Bound
  114. 7rt3: Crystal Structure of Kras G12D with Compound 24 (4-(4-[(1r,5s)-3,8- Diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2s,4s,7ar)-2- Fluorotetrahydro-1h-pyrrolizin-7a(5h)-yl]methoxy}pyrido[4,3- D]pyrimidin-7-yl)naphthalen-2-ol) Bound
  115. 7rt4: Kras G12D in Complex with Compound 5b (7-(8-chloronaphthalen-1-yl)-8- Fluoro-2-{[(2s)-1-methylpyrrolidin-2-yl]methoxy}-4-(piperazin-1-yl) Pyrido[4,3-d]pyrimidine)
  116. 7rt5: Crystal Structure of Kras G12D with Compound 36 (4-[(1r,5s)-3,8- Diazabicyclo[3.2.1]octan-3-yl]-7-(8-ethynyl-7-fluoronaphthalen-1-yl)- 8-fluoro-2-{[(4s,7as)-tetrahydro-1h-pyrrolizin-7a(5h)- Yl]methoxy}pyrido[4,3-d]pyrimidine) Bound
  117. 7ew9: Gdp-bound Kras G12D in Complex with Th-z816
  118. 7ewa: Gdp-bound Kras G12D in Complex with Th-z827
  119. 7ewb: Gdp-bound Kras G12D in Complex with Th-z835
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