EC 4.2.1, Hydro- Lyases or dehydratases that catalyze cleavage of carbon- oxygen bonds by elimination of water molecule

EC 4.2.1 sub-subclass definition

Members of EC 4.2.1 sub-subclass

• EC 4.2.1.1 - carbonate hydro-lyase (carbon-dioxide-forming)
• EC 4.2.1.2 - (S)-malate hydro-lyase (fumarate-forming)
• EC 4.2.1.3 - citrate(isocitrate) hydro-lyase (cis-aconitate-forming)
• EC 4.2.1.4 - citrate hydro-lyase
• EC 4.2.1.5 - D-arabinonate hydro-lyase (2-dehydro-3-deoxy-D-arabinonate-forming)
• EC 4.2.1.6 - D-galactonate hydro-lyase(2-dehydro-3-deoxy-D-galactonate-forming)
• EC 4.2.1.7 - D-altronate hydro-lyase(2-dehydro-3-deoxy-D-gluconate-forming)
• EC 4.2.1.8 - D-mannonate hydro-lyase(2-dehydro-3-deoxy-D-gluconate-forming)
• EC 4.2.1.9 - 2,3-dihydroxy-3-methylbutanoate hydro-lyase (3-methyl-2-oxobutanoate-forming)
• EC 4.2.1.10 - 3-dehydroquinate hydro-lyase (3-dehydroshikimate-forming)
• EC 4.2.1.11 - 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)
• EC 4.2.1.12 - 6-phospho-D-gluconate hydro-lyase(2-dehydro-3-deoxy-6-phospho-D-gluconate-forming)
• EC 4.2.1.13 - obsolete, reclassified now as L-serine ammonia-lyase, EC 4.3.1.17
• EC 4.2.1.14 - obsolete, reclassified now as L-serine ammonia-lyase, EC 4.3.1.17
• EC 4.2.1.15 - obsolete, reclassified now as cystathionine γ-lyase, EC 4.4.1.1
• EC 4.2.1.16 - obsolete, reclassified now as L-serine ammonia-lyase, EC 4.3.1.17
• EC 4.2.1.17 - (3S)-3-hydroxyacyl-CoA hydro-lyase
• EC 4.2.1.18 - (S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming)
• EC 4.2.1.19 - D-erythro-1-(imidazol-4-yl)glycerol-3-phosphate hydro-lyase [3-(imidazol-4-yl)-2-oxopropyl-phosphate-forming]
• EC 4.2.1.20 - L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]
• EC 4.2.1.21 - obsolete, reclassified now as cystathionine β-synthase, EC 4.2.1.22
• EC 4.2.1.22 - L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)
• EC 4.2.1.23 - obsolete, deleted
• EC 4.2.1.24 - 5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)
• EC 4.2.1.25 - L-arabinonate hydro-lyase (2-dehydro-3-deoxy-L-arabinonate-forming)
• EC 4.2.1.26 - obsolete, reclassified now as glucosaminate ammonia-lyase, EC 4.3.1.9
• EC 4.2.1.27 - 3-oxopropanoate hydro-lyase (propynoate-forming)
• EC 4.2.1.28 - propane-1,2-diol hydro-lyase (propanal-forming)
• EC 4.2.1.29 - obsolete, reclassified now as indoleacetaldoxime dehydratase, EC 4.99.1.6
• EC 4.2.1.30 - glycerol hydro-lyase (3-hydroxypropanal-forming)
• EC 4.2.1.31 - (R)-malate hydro-lyase (maleate-forming)
• EC 4.2.1.32 - (R,R)-tartrate hydro-lyase (oxaloacetate-forming)
• EC 4.2.1.33 - (2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)
• EC 4.2.1.34 - (S)-2-methylmalate hydro-lyase (2-methylfumarate-forming)
• EC 4.2.1.35 - (R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)
• EC 4.2.1.36 - (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(Z)-but-1-ene-1,2,4-tricarboxylate-forming]
• EC 4.2.1.37 - obsolete, reclassified now as trans-epoxysuccinate hydrolase, EC 3.3.2.4
• EC 4.2.1.38 - obsolete, reclassified now as L-serine ammonia-lyase, EC 4.3.1.17
• EC 4.2.1.39 - D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)
• EC 4.2.1.40 - D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)
• EC 4.2.1.41 - 5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating; 2,5-dioxopentanoate-forming)
• EC 4.2.1.42 - D-galactarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)
• EC 4.2.1.43 - 2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)
• EC 4.2.1.44 - 2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase (3,5/4-trihydroxycyclohexa-1,2-dione-forming)
• EC 4.2.1.45 - CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming)
• EC 4.2.1.46 - dTDP-glucose 4,6-hydro-lyase (dTDP-4-dehydro-6-deoxy-D-glucose-forming)
• EC 4.2.1.47 - GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming)
• EC 4.2.1.48 - D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming)
• EC 4.2.1.49 - 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase (urocanate-forming)
• EC 4.2.1.50 - L-serine hydro-lyase [adding pyrazole; 3-(pyrazol-1-yl)-L-alanine-forming]
• EC 4.2.1.51 - prephenate hydro-lyase (decarboxylating; phenylpyruvate-forming)
• EC 4.2.1.52 - L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing; (S)-2,3-dihydropyridine-2,6-dicarboxylate-forming]
• EC 4.2.1.53 - (R)-10-hydroxystearate 10-hydro-lyase (oleate-forming)
• EC 4.2.1.54 - lactoyl-CoA hydro-lyase (acryloyl-CoA-forming)
• EC 4.2.1.55 - (3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming)
• EC 4.2.1.56 - citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)
• EC 4.2.1.57 - 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase [3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA-forming]
• EC 4.2.1.58 - (3R)-3-hydroxybutanoyl-[acyl-carrier protein] hydro-lyase (but-2-enoyl-[acyl-carrier protein]-forming)
• EC 4.2.1.59 - (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] hydro-lyase (oct-2-enoyl-[acyl-carrier protein]-forming)
• EC 4.2.1.60 - (3R)-3-hydroxydecanoyl-[acyl-carrier protein] hydro-lyase
• EC 4.2.1.61 - (3R)-3-hydroxypalmitoyl-[acyl-carrier protein] hydro-lyase (hexadec-2-enoyl-[acyl-carrier protein]-forming)
• EC 4.2.1.62 - 5α-ergosta-7,22-diene-3β,5-diol 5,6-hydro-lyase (ergosterol-forming)
• EC 4.2.1.63 - obsolete, reclassified now as microsomal epoxide hydrolase, EC 3.3.2.9 and soluble epoxide hydrolase, EC 3.3.2.10
• EC 4.2.1.64 - obsolete, reclassified now as microsomal epoxide hydrolase, EC 3.3.2.9 and soluble epoxide hydrolase, EC 3.3.2.10
• EC 4.2.1.65 - L-asparagine hydro-lyase (3-cyanoalanine-forming)
• EC 4.2.1.66 - formamide hydro-lyase (cyanide-forming)
• EC 4.2.1.67 - D-fuconate hydro-lyase(2-dehydro-3-deoxy-D-fuconate-forming)
• EC 4.2.1.68 - L-fuconate hydro-lyase (2-dehydro-3-deoxy-L-fuconate-forming)
• EC 4.2.1.69 - urea hydro-lyase (cyanamide-forming)
• EC 4.2.1.70 - uracil hydro-lyase (adding D-ribose 5'-phosphate; pseudouridine-5'-phosphate-forming)
• EC 4.2.1.71 - obsolete, identical to acetylenecarboxylate hydratase, EC 4.2.1.27
• EC 4.2.1.72 - obsolete, reclassified now as acetylenedicarboxylate decarboxylase , EC 4.1.1.78
• EC 4.2.1.73 - protoaphin-aglucone hydro-lyase (cyclizing; xanthoaphin-forming)
• EC 4.2.1.74 - long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase
• EC 4.2.1.75 - hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming)
• EC 4.2.1.76 - UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming)
• EC 4.2.1.77 - trans-L-3-hydroxyproline hydro-lyase (Δ¹-pyrroline-2-carboxylate-forming)
• EC 4.2.1.78 - 4-hydroxyphenylacetaldehyde hydro-lyase [adding dopamine; (S)-norcoclaurine-forming]
• EC 4.2.1.79 - (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]
• EC 4.2.1.80 - 4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming)
• EC 4.2.1.81 - (S,S)-tartrate hydro-lyase (oxaloacetate-forming)
• EC 4.2.1.82 - D-xylonate hydro-lyase(2-dehydro-3-deoxy-D-xylonate-forming)
• EC 4.2.1.83 - 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase[(E)-4-oxobut-1-ene-1,2,4-tricarboxylate-forming]
• EC 4.2.1.84 - aliphatic-amide hydro-lyase (nitrile-forming)
• EC 4.2.1.85 - (2R,3S)-2,3-dimethylmalate hydro-lyase (dimethylmaleate-forming)
• EC 4.2.1.86 - obsolete, deleted due to repetition of 16α-hydroxyprogesterone dehydratase, EC 4.2.1.98
• EC 4.2.1.87 - 1-(4-hydroxyphenyl)-2-aminoethanol hydro-lyase [deaminating; (4-hydroxyphenyl)acetaldehyde-forming]
• EC 4.2.1.88 - 1-(4-hydroxyphenyl)-2-(methylamino)ethanol hydro-lyase (methylamine-forming)
• EC 4.2.1.89 - L-carnitine hydro-lyase [4-(trimethylammonio)but-2-enoate-forming]
• EC 4.2.1.90 - L-rhamnonate hydro-lyase (2-dehydro-3-deoxy-L-rhamnonate-forming)
• EC 4.2.1.91 - L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming)
• EC 4.2.1.92 - (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]
• EC 4.2.1.93 - (6S)-6β-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ATP-hydrolysing; NADH-forming)
• EC 4.2.1.94 - scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming)
• EC 4.2.1.95 - kievitone-hydrate hydro-lyase (kievitone-forming)
• EC 4.2.1.96 - (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming]
• EC 4.2.1.97 - phaseollidin-hydrate hydro-lyase (phaseollidin-forming)
• EC 4.2.1.98 - 16α-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming)
• EC 4.2.1.99 - (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]
• EC 4.2.1.100 - 6-hydroxycyclohex-1-enecarbonyl-CoA hydro-lyase (cyclohexa-1,5-dienecarbonyl-CoA-forming)
• EC 4.2.1.101 - 4-hydroxy-3-methoxyphenyl-β-hydroxypropanoyl-CoA hydro-lyase (feruloyl-CoA-forming)
• EC 4.2.1.102 - obsolete, reclassified now as cyclohexa-1,5-dienecarbonyl-CoA hydratase, EC 4.2.1.100
• EC 4.2.1.103 - N-cyclohexylformamide hydro-lyase (cyclohexyl-isocyanide-forming)
• EC 4.2.1.104 - carbamate hydro-lyase
• EC 4.2.1.105 - 2,7,4'-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
• EC 4.2.1.106 - 7α,12α-dihydroxy-3-oxochol-4-enoate hydro-lyase (12α-hydroxy-3-oxochola-4,6-dienoate-forming)
• EC 4.2.1.107 - (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl-CoA hydro-lyase [(24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA-forming]
• EC 4.2.1.108 - N⁴acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming)
• EC 4.2.1.109 - S-methyl-5-thio-D-ribulose-1-phosphate 4-hydro-lyase [5-(methylthio)-2,3-dioxopentyl-phosphate-forming]
• EC 4.2.1.110 - 1,5-anhydro-D-fructose hydro-lyase (microthecin-forming)
• EC 4.2.1.111 - 1,5-anhydro-D-fructose hydro-lyase (ascopyrone-M-forming)
• EC 4.2.1.112 - acetaldehyde hydro-lyase (acetylene-forming)
• EC 4.2.1.113 - (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate hydrolyase (2-succinylbenzoate-forming)