EC 4.2.1.20 - L- serine hydro- lyase [adding 1- C- (indol- 3- yl) glycerol 3- phosphate; L- tryptophan and glyceraldehyde- 3- phosphate- forming] (tryptophan synthase)

3D structures of EC 4.2.1.20 - tryptophan synthase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1a50: Crystal Structure of Wild-type Tryptophan Synthase Complexed with 5-fluoroindole Propanol Phosphate
2. 1a5a: Cryo-crystallography of a True Substrate, Indole-3-glycerol Phosphate, Bound to a Mutant (ALPHAD60N) Tryptophan Synthase ALPHA2BETA2 Complex Reveals The Correct Orientation of Active Site Alpha Glu 49
3. 1a5b: Cryo-crystallography of a True Substrate, Indole-3-glycerol Phosphate, Bound to a Mutant (alpha D60N) Tryptophan Synthase ALPHA2BETA2 Complex Reveals The Correct Orientation of Active Site Alpha Glu 49
4. 1a5s: Crystal Structure of Wild-type Tryptophan Synthase Complexed with 5-fluoroindole Propanol Phosphate and L-ser Bound as Amino Acrylate to The Beta Site
5. 1beu: Trp Synthase (D60N-IPP-SER) with K+
6. 1bks: Tryptophan Synthase (e.c.4.2.1.20) from Salmonella Typhimurium
7. 1c29: Crystal Structure of The Complex of Bacterial Tryptophan Synthase with The Transition State Analogue Inhibitor 4-(2- Hydroxyphenylthio)-1-butenylphosphonic Acid
8. 1c8v: Crystal Structure of The Complex of Bacterial Tryptophan Synthase with The Transition State Analogue Inhibitor 4-(2- Hydroxyphenylthio)-butylphosphonic Acid
9. 1c9d: Crystal Structure of The Complex of Bacterial Tryptophan Synthase with The Transition State Analogue Inhibitor 4-(2- Hydroxy-4-fluorophenylthio)-butylphosphonic Acid
10. 1cw2: Crystal Structure of The Complex of Bacterial Tryptophan Synthase with The Transition State Analogue Inhibitor 4-(2- Hydroxyphenylsulfinyl)-butylphosphonic Acid
11. 1cx9: Crystal Structure of The Complex of Bacterial Tryptophan Synthase with The Transition State Analogue Inhibitor 4-(2- Aminophenylthio)-butylphosphonic Acid
12. 1fuy: Crystal Structure of BETAA169L/BETAC170W Double Mutant of Tryptophan Synthase Complexed with 5-fluoro-indole- Propanol Phosphate
13. 1geq: Entropic Stabilization of The Tryptophan Synthase A-subunit from a Hyperthermophile, Pyrococcus Furiosus: X-ray Analysis and Calorimetry
14. 1k3u: Crystal Structure of Wild-type Tryptophan Synthase Complexed with N-[1h-indol-3-yl-acetyl]aspartic Acid
15. 1k7e: Crystal Structure of Wild-type Tryptophan Synthase Complexed with N-[1h-indol-3-yl-acetyl]glycine Acid
16. 1k7f: Crystal Structure of Wild-type Tryptophan Synthase Complexed with N-[1h-indol-3-yl-acetyl]valine Acid
17. 1k7x: Crystal Structure of The BETA-SER178PRO Mutant of Tryptophan Synthase
18. 1k8x: Crystal Structure of ALPHAT183V Mutant of Tryptophan Synthase from Salmonella Typhimurium
19. 1k8y: Crystal Structure of The Tryptophan Synthase BETA-SER178PRO Mutant Complexed with D,l-alpha-glycerol-3-phosphate
20. 1k8z: Crystal Structure of The Tryptophan Synthase BETA-SER178PRO Mutant Complexed with N-[1h-indol-3-yl-acetyl]glycine Acid
21. 1kfc: Crystal Structure of ALPHAT183V Mutant of Tryptophan Synthase from Salmonella Typhimurium with Indole Propanol Phosphate
22. 1kfj: Crystal Structure of Wild-type Tryptophan Synthase Complexed with L-serine
23. 1kfk: Crystal Structure of Tryptophan Synthase from Salmonella Typhimurium
24. 3nav: Crystal Structure of an Alpha Subunit of Tryptophan Synthase from Vibrio Cholerae O1 Biovar El Tor Str. N16961
25. 1qop: Crystal Structure of Wild-type Tryptophan Synthase Complexed with Indole Propanol Phosphate
26. 1qoq: Crystal Structure of Wild-type Tryptophan Synthase Complexed with Indole Glycerol Phosphate
27. 1rd5: Crystal Structure of Tryptophan Synthase Alpha Chain Homolog Bx1: a Member of The Chemical Plant Defense System
28. 1tjp: Crystal Structure of Wild-type Tryptophan Synthase Complexed with 1-[(2-hydroxylphenyl)amino]3- Glycerolphosphate
29. 1tjr: Crystal Structure of Wild-type Bx1 Complexed with a Sulfate Ion
30. 1ttp: Tryptophan Synthase (e.c.4.2.1.20) in The Presence of Cesium, Room Temperature
31. 1ttq: Tryptophan Synthase (e.c.4.2.1.20) in The Presence of Potassium at Room Temperature
32. 1ubs: Tryptophan Synthase (e.c.4.2.1.20) with a Mutation of Lys 87->thr in The B Subunit and in The Presence of Ligand L-serine
33. 1ujp: Crystal Structure of Tryptophan Synthase A-subunit from Thermus Thermophilus Hb8
34. 1v7y: Crystal Structure of Tryptophan Synthase Alpha-subunit from Escherichia Coli at Room Temperature
35. 1v8z: X-ray Crystal Structure of The Tryptophan Synthase B2 Subunit from Hyperthermophile, Pyrococcus Furiosus
36. 3cep: Structure of a Tryptophan Synthase Quinonoid Intermediate
37. 1wbj: Wildtype Tryptophan Synthase Complexed with Glycerol Phosphate
38. 1wdw: Structural Basis of Mutual Activation of The Tryptophan Synthase A2B2 Complex from a Hyperthermophile, Pyrococcus Furiosus
39. 1wq5: Crystal Structure of Tryptophan Synthase Alpha-subunit from Escherichia Coli
40. 1wxj: Crystal Structure of Tryptophan Synthase A-subunit with Indole-3-propanol Phosphate from Thermus Thermophilus Hb8
41. 1x1q: Crystal Structure of Tryptophan Synthase Beta Chain from Thermus Thermophilus Hb8
42. 1xc4: Crystal Structure of Wild-type Tryptophan Synthase Alpha- Subunits from Escherichia Coli
43. 1xcf: Crystal Structure of P28L/Y173F Tryptophan Synthase Alpha- Subunits from Escherichia Coli
44. 2wsy: Crystal Structure of Wild-type Tryptophan Synthase
45. 6v82: Crystal Structure of Tryptophan Synthase from Chlamydia Trachomatis D/uw-3/cx
46. 7a20: Azobenzene-based Inhibitors for Tryptophan Synthase
47. 2tys: Crystal Structures of Mutant (BETAK87T) Tryptophan Synthase Alpha2 Beta2 Complex with Ligands Bound to The Active Sites of The Alpha and Beta Subunits Reveal Ligand-induced Conformational Changes
48. 2tsy: Crystal Structures of Mutant (BETAK87T) Tryptophan Synthase Alpha2 Beta2 Complex with Ligands Bound to The Active Sites of The Alpha and Beta Subunits Reveal Ligand-induced Conformational Changes
49. 2trs: Crystal Structures of Mutant (BETAK87T) Tryptophan Synthase Alpha2 Beta2 Complex with Ligands Bound to The Active Sites of The Alpha and Beta Subunits Reveal Ligand-induced Conformational Changes
50. 2rhg: Tryptophan Synthase Complexed with Igp, Ph 7.0, Internal Aldimine
51. 2rh9: Tryptophan Synthase Complexed with Igp, Internal Aldimine, Ph 9.0
52. 2cle: Tryptophan Synthase in Complex with N-(4'- Trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (f6) - Lowf6 Complex
53. 2clf: Tryptophan Synthase in Complex with N-(4'- Trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (f6) - Highf6 Complex
54. 2clh: Tryptophan Synthase in Complex with (naphthalene-2'- Sulfonyl)-2-amino-1-ethylphosphate (f19)
55. 2cli: Tryptophan Synthase in Complex with N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (f9)
56. 2clk: Tryptophan Synthase in Complex with D-glyceraldehyde 3- Phosphate (G3P)
57. 2cll: Tryptophan Synthase (external Aldimine State) in Complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1- Ethylphosphate (f9)
58. 2clm: Tryptophan Synthase (external Aldimine State) in Complex with N-(4'-trifluoromethoxybenzoyl)-2-amino-1- Ethylphosphate (F6F)
59. 2clo: Tryptophan Synthase (external Aldimine State) in Complex with (naphthalene-2'-sulfonyl)-2-amino-1-ethylphosphate (f19)
60. 2dh5: Crystal Structure of E. Coli Holo-trpb
61. 2dh6: Crystal Structure of E. Coli Apo-trpb
62. 6c73: Tryptophan Synthase Q114A Mutant (internal Aldimine State) in Complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) with Cesium Ion Bound in The Metal Coordination Site
63. 2dzp: Structure of Mutant Tryptophan Synthase Alpha-subunit (D17N) from a Hyperthermophile, Pyrococcus Furiosus
64. 2dzs: Structure of Mutant Tryptophan Synthase Alpha-subunit (E103A) from a Hyperthermophile, Pyrococcus Furiosus
65. 2dzt: Structure of Mutant Tryptophan Synthase Alpha-subunit (D110A) from a Hyperthermophile, Pyrococcus Furiosus
66. 2dzu: Structure of Mutant Tryptophan Synthase Alpha-subunit (D110N) from a Hyperthermophile, Pyrococcus Furiosus
67. 2dzv: Structure of Mutant Tryptophan Synthase Alpha-subunit (D146A) from a Hyperthermophile, Pyrococcus Furiosus
68. 2dzw: Structure of Mutant Tryptophan Synthase Alpha-subunit (E244A) from a Hyperthermophile, Pyrococcus Furiosus
69. 2dzx: Structure of Mutant Tryptophan Synthase Alpha-subunit (e131- 132a) from a Hyperthermophile, Pyrococcus Furiosus
70. 2e09: Structure of Mutant Tryptophan Synthase Alpha-subunit (E74A) from a Hyperthermophile, Pyrococcus Furiosus
71. 2o2j: Mycobacterium Tuberculosis Tryptophan Synthase Beta Chain Dimer (apoform)
72. 2o2e: Mycobacterium Tuberculosis Tryptophan Synthase Beta Subunit Dimer (apoform)
73. 6ami: Engineered Tryptophan Synthase B-subunit from Pyrococcus Furiosus, PFTRPB4D11 with Trp Non-covalently Bound
74. 6amh: Engineered Tryptophan Synthase B-subunit from Pyrococcus Furiosus, PFTRPB4D11 with Ser Bound as E(aex1)
75. 6amc: Engineered Tryptophan Synthase B-subunit from Pyrococcus Furiosus, PFTRPB4D11
76. 6am9: Engineered Tryptophan Synthase B-subunit from Pyrococcus Furiosus, PFTRPB2B9, with Ser-bound in a Predominantly Closed State.
77. 6am8: Engineered Tryptophan Synthase B-subunit from Pyrococcus Furiosus, PFTRPB2B9 with Trp Bound as E(aex2)
78. 6am7: Engineered Tryptophan Synthase B-subunit from Pyrococcus Furiosus, PFTRPB2B9
79. 2ekc: Structural Study of Project Id Aq_1548 from Aquifex Aeolicus Vf5
80. 6o1h: Tryptophan Synthase Q114A Mutant in Complex with N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Enzyme Alpha-site, Cesium Ion at The Metal Coordination Site, and 2-aminophenol Quinonoid at The Enzyme Beta Site
81. 2j9x: Tryptophan Synthase in Complex with Gp, Alpha-d,l-glycerol- Phosphate, Cs, Ph6.5 - Alpha Aminoacrylate Form - (gp)e(a- A)
82. 2j9y: Tryptophan Synthase Q114N Mutant in Complex with Compound II
83. 2j9z: Tryptophan Synthase T110 Mutant Complex
84. 6vfd: Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at The Metal Coordination Site and 2-aminophenol Quinonoid at The Enzyme Beta Site
85. 6usa: Crystal Structure of Tryptophan Synthase from M. Tuberculosis - Aminoacrylate- and Gsk1-bound Form
86. 6u6c: Crystal Structure of Tryptophan Synthase from M. Tuberculosis - Aminoacrylate- and Gsk2-bound Form
87. 3pr2: Tryptophan Synthase Indoline Quinonoid Structure with F9 Inhibitor in Alpha Site
88. 6ouy: The Crystal Structure of The Isolate Tryptophan Synthase Alpha-chain from Salmonella Enterica Serovar Typhimurium at 1.60 Angstrom Resolution
89. 6oso: The Crystal Structure of The Isolate Tryptophan Synthase Alpha-chain from Salmonella Enterica Serovar Typhimurium at 1.75 Angstrom Resolution
90. 3tha: Tryptophan Synthase Subunit Alpha from Campylobacter Jejuni.
91. 6ub9: Crystal Structure of Tryptophan Synthase from M. Tuberculosis - Aminoacrylate- and Brd6309-bound Form
92. 6uap: Crystal Structure of Tryptophan Synthase from M. Tuberculosis - Open Form with Brd6309 Bound
93. 6qky: Tryptophan Synthase Subunit Alpha from Streptococcus Pneumoniae with 3d Domain Swap in The Core of Tim Barrel
94. 3vnd: Crystal Structure of Tryptophan Synthase Alpha-subunit from The Psychrophile Shewanella Frigidimarina K14-2
95. 6hul: Sulfolobus Solfataricus Tryptophan Synthase Ab Complex
96. 6hte: Sulfolobus Solfataricus Tryptophan Synthase B2A
97. 6eqn: Sulfolobus Solfataricus Tryptophan Synthase B2O
98. 6e9p: Crystal Structure of Tryptophan Synthase from M. Tuberculosis - Open Form with Brd0059 Bound
99. 6dzo: Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant BETA-Q114A with 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl Dihydrogen Phosphate (F9F) at The Alpha-site, Cesium Ion at The Metal Coordination Site, and [3-hydroxy-2-methyl-5-phosphonooxymethyl- Pyridin-4-ylmethyl]-serine (pls) at The Beta-site.
100. 6dz4: Crystal Structure of Salmonella Typhimurium Tryptophan Synthase with Sodium Ion at The Metal Coordination Site and [3-hydroxy-2-methyl-5- Phosphonooxymethyl-pyridin-4-ylmethyl]-serine (pls) at The Beta-site.
101. 6dwe: Crystal Structure of Tryptophan Synthase from M. Tuberculosis - Aminoacrylate- and Brd0059-bound Form
102. 6duc: Crystal Structure of Mutant BETA-K167T Tryptophan Synthase in Complex with Inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1- Ethylphosphate (F9F) at The Alpha-site, Cesium Ion at The Metal Coordination Site, and 2-aminophenol Quinonoid (1d0) at The Beta-site
103. 6d0v: Tryptophan Synthase Q114A Mutant in Complex with Inhibitor N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Alpha-site, Aminoacrylate (P1T) at The Beta Site, and Cesium Ion at The Metal Coordination Site
104. 6cuz: Engineered Trpb from Pyrococcus Furiosus, PFTRPB7E6 with (2s,3r)- Ethylserine Bound as The Amino-acrylate
105. 6cuv: Engineered Holo Trpb from Pyrococcus Furiosus, PFTRPB7E6
106. 6cut: Engineered Holo Trpb from Pyrococcus Furiosus, PFTRPB7E6 with (2s,3s)- Isopropylserine Bound as The External Aldimine
107. 4hn4: Tryptophan Synthase in Complex with Alpha Aminoacrylate E(a-a) Form and The F9 Inhibitor in The Alpha Site
108. 4hpj: Crystal Structure of Tryptophan Synthase at 1.45 a Resolution in Complex with 2-aminophenol Quinonoid in The Beta Site and The F9 Inhibitor in The Alpha Site
109. 4hpx: Crystal Structure of Tryptophan Synthase at 1.65 a Resolution in Complex with Alpha Aminoacrylate E(a-a) and Benzimidazole in The Beta Site and The F9 Inhibitor in The Alpha Site
110. 4ht3: The Crystal Structure of Salmonella Typhimurium Tryptophan Synthase at 1.30a Complexed with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino- 1-ethylphosphate (f9) Inhibitor in The Alpha Site, Internal Aldimine
111. 4kkx: Crystal Structure of Tryptophan Synthase from Salmonella Typhimurium with 2-aminophenol Quinonoid in The Beta Site and The F6 Inhibitor in The Alpha Site
112. 4neg: The Crystal Structure of Tryptophan Synthase Subunit Beta from Bacillus Anthracis Str. 'ames Ancestor'
113. 5vm5: Engineered Tryptophan Synthase B-subunit from Pyrococcus Furiosus, PFTRPB2B9, with Ser Bound
114. 5tcj: Crystal Structure of Tryptophan Synthase from M. Tuberculosis - Aminoacrylate and Brd4592-bound Form
115. 5tci: Crystal Structure of Tryptophan Synthase from M. Tuberculosis - Brd4592-bound Form
116. 5tch: Crystal Structure of Tryptophan Synthase from M. Tuberculosis - Ligand-free Form, TRPA-G66V Mutant
117. 5tcg: Crystal Structure of Tryptophan Synthase from M. Tuberculosis - Aminoacrylate-bound Form
118. 5tcf: Crystal Structure of Tryptophan Synthase from M. Tuberculosis - Ligand-free Form
119. 5t6m: Structure of The Tryptophan Synthase B-subunit from Pyroccus Furiosus with B-methyltryptophan Non-covalently Bound
120. 5ocw: Structure of Mycobacterium Tuberculosis Tryptophan Synthase in Space Group F222
121. 5n2p: Sulfolobus Solfataricus Tryptophan Synthase a
122. 5kzm: Crystal Structure of Tryptophan Synthase Alpha-beta Chain Complex from Francisella Tularensis
123. 5kmy: Crystal Structure of Tryptophan Synthase Subunit Alpha from Legionella Pneumophila Str. Paris
124. 5kin: Crystal Structure of Tryptophan Synthase Alpha Beta Complex from Streptococcus Pneumoniae
125. 5k9x: Crystal Structure of Tryptophan Synthase Alpha Chain from Legionella Pneumophila Subsp. Pneumophila
126. 5ixj: Tryptophan Synthase Beta-subunit from Pyrococcus Furiosus with L- Threonine Non-covalently Bound in The Active Site
127. 5e0k: X-ray Crystal Structure of Tryptophan Synthase Complex from Pyrococcus Furiosus at 2.76 a
128. 5dw3: Tryptophan Synthase Beta-subunit from Pyrococcus Furiosus with Product L-tryptophan Non-covalently Bound in The Active Site
129. 5dw0: Trpb from Pyrococcus Furiosus with L-serine Bound as The External Aldimine
130. 5dvz: Holo Trpb from Pyrococcus Furiosus
131. 5cgq: Crystal Structure of Tryptophan Synthase from Salmonella Typhimurium in Complex with F9 Ligand in The Alpha-site and The Product L- Tryptophan in The Beta-site.
132. 5bw6: Tryptophan Synthase from Salmonella Typhimurium in Complex with a Single Molecule of 2-({[4-(trifluoromethoxy)phenyl]carbonyl}amino) Ethyl Dihydrogen Phosphate (f6) in The Alpha-site.
133. 4qys: Trpb2 Enzymes
134. 4zqc: Tryptophan Synthase from Salmonella Typhimurium in Complex with Two Molecules of N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) Inhibitor in The Alpha-site and a Single F6F Molecule in The Beta-site at 1.54 Angstrom Resolution.
135. 4wx2: Crystal Structure of Tryptophan Synthase from Salmonella Typhimurium in Complex with Two F6F Molecules in The Alpha-site and One F6F Molecule in The Beta-site
136. 4xug: Crystal Structure of Tryptophan Synthase from Salmonella Typhimurium in Complex with 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl Dihydrogen Phosphate (F9F) Inhibitor in The Alpha Site and Ammonium Ion in The Metal Coordination Site.
137. 4y6g: Crystal Structure of Tryptophan Synthase from Salmonella Typhimurium in Complex with N-(4'-trifluoromethoxybenzoyl)-2-amino-1- Ethylphosphate (F6F) Inhibitor in The Alpha-site and Beta-site.
138. 6vnt: Tryptophan Synthase in Complex with Inhibitor N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Alpha-site, Aminoacrylate at The Beta Site, and Sodium Ion at The Metal Coordination Site at 1.25 Angstrom Resolution
139. 6xnc: Salmonella Typhimurium Tryptophan Synthase Complexed with L-tryptophan and D-glycerol-3-phosphate
140. 6xoy: Salmonella Typhimurium Tryptophan Synthase Complexed with D-tryptophan and D-glycerol-3-phosphate
141. 6xrh: Salmonella Typhimurium Tryptophan Synthase Complexed with Oxindolyl-l- Alanine and D-glycerol-3-phosphate
142. 6xt0: Salmonella Typhimurium Tryptophan Synthase Complexed with Dioxindolyl- L-alanine and D-glycerol-3-phosphate
143. 6wdu: The External Aldimine Form of The Salmonella Thypi Wild-type Tryptophan Synthase in Open Conformation Showing Multiple Side Chain Conformations for The Residue Beta Q114 and Sodium Ion at The Metal Coordination Site. One of The Beta-q114 Rotamer Conformations Allows a Hydrogen Bond to Form with The Plp Oxygen at The Position 3 in The Ring.
144. 6wx3: High Resolution Tryptophan Synthase Crystal Structure from Salmonella Typhimurium in Complex with F9 Inhibitor in The Alpha-site, Cesium Ion at The Metal Coordination Site and Internal Aldimine Form.
145. 6x0c: Tryptophan Synthase Mutant BETA-Q114A in Complex with Cesium Ion at The Metal Coordination Site and Aminoacrylate and Benzimidazole at The Enzyme Beta Site
146. 6xe3: Salmonella Typhimurium Tryptophan Synthase BETA-S377A Mutant in Complex with Inhibitor F9 at The Enzyme Alpha-site, Cesium Ion at The Metal Coordination Site and Carbanion III E(c3) at The Enzyme Beta- Site.
147. 6xin: The Crystal Structure of Tryptophan Synthase from Salmonella Enterica Serovar Typhimurium in Complex with (2s)-3-amino-3-imino-2- Phenyldiazenylpropanamide at The Enzyme Alpha-site.
148. 6xsy: The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant BETA-S377A with Inhibitor 2-({[4- (trifluoromethoxy)phenyl]sulfonyl}amino)ethyl Dihydrogen Phosphate (F9F) at The Alpha-site, Cesium Ion at The Metal Coordination Site, and (e)-n-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4- Yl}methylidene)-l-serine (kou) at The Beta-site
149. 7jhw: The Internal Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant BETA-S377A in Complex with Inhibitor 2- ({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl Dihydrogen Phosphate (F9F) at The Alpha-site and Cesium Ion at The Metal Coordination Site
150. 7jll: The Internal Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant BETA-S377A in Complex with Inhibitor 2- ({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl Dihydrogen Phosphate (F9F) at The Alpha-site, Cesium Ion at The Metal Coordination Site and L-tryptophan at The Enzyme Beta-site
151. 7jmq: The External Aldimine Form of The Mutant BETA-S377A Salmonella Thypi Tryptophan Synthase in Open Conformation Showing Dual Side Chain Conformations for The Residue Beta-q114, Sodium Ion at The Metal Coordination Site, and F9 Inhibitor at The Alpha-site. One of The Beta-q114 Rotamer Conformations Allows a Hydrogen Bond to Form with The Plp Oxygen at The Position 3 in The Ring
152. 7jqw: The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant BETA-S377A in Complex with Cesium Ion at The Metal Coordination Site. The Single Beta-q114 Rotamer Conformation Allows a Hydrogen Bond to Form with The Plp Oxygen at The Position 3 in The Ring
153. 7jtt: The External Aldimine Crystal Structure of Salmonella Typhimurium Tryptophan Synthase Mutant BETA-S377A in Complex F9 Inhibitor at The Alpha-site and Cesium Ion at The Metal Coordination Site. The Single Beta-q114 Rotamer Conformation Allows a Hydrogen Bond to Form with The Plp Oxygen at The Position 3 in The Ring
154. 7k0b: The Internal Aldimine Form of Salmonella Typhimurium Tryptophan Synthase Mutant BETA-Q114A with Cesium Ion at The Metal Coordination Site. a Random BETA-P270L Mutation Was Inserted during Pcr Step
155. 7k5a: The External Aldimine Form of Salmonella Typhimurium Tryptophan Synthase Mutant BETA-Q114A in Complex with Cesium Ion at The Metal Coordination Site.
156. 7m2l: The Internal Aldimine Form of The Wild-type Salmonella Typhimurium Tryptophan Synthase in Complex with N-(4'-trifluoromethoxybenzoyl)-2- Amino-1-ethylphosphate (F6F) Inhibitor at The Alpha-and Beta-site, Sodium Ion at The Metal Coordination Site, and Another F6F Molecule at The Enzyme Beta-site at 1.60 Angstrom Resolution. Two of The Beta- Q114 Rotamer Conformations Allows a Hydrogen Bond to Form with The Plp Oxygen at The Position 3 in The Ring
157. 7m3s: The Internal Aldimine Form of The Wild-type Salmonella Typhimurium Tryptophan Synthase in Complex with N-(4'-trifluoromethoxybenzoyl)-2- Amino-1-ethylphosphate (F6F) Inhibitor at The Alpha-and Beta-site, Sodium Ion at The Metal Coordination Site, and Another F6F Molecule at The Enzyme Beta-site at 1.55 Angstrom Resolution. One of The Beta- Q114 Rotamer Conformations Allows a Hydrogen Bond to Form with The Plp Oxygen at The Position 3 in The Ring
158. 7ka1: 1.60 Angstrom Resolution Crystal Structure of The BETA-Q114A Mutant Tryptophan Synthase in Complex with Inhibitor N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Alpha-site, Aminoacrylate at The Beta Site, and Cesium Ion at The Metal Coordination Site
159. 7kbn: 1.60 Angstrom Resolution Crystal Structure of The BETA-Q114A Mutant of Tryptophan Synthase in Complex with N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Enzyme Alpha-site, Cesium Ion at The Metal Coordination Site, and 2-aminophenol Quinonoid at The Enzyme Beta Site
160. 7me8: The Internal Aldimine Form of The Wild-type Salmonella Typhimurium Tryptophan Synthase in Complex with N-(4'-trifluoromethoxybenzoyl)-2- Amino-1-ethylphosphate (F6F) Inhibitor at The Beta-site, Sodium Ion at The Metal Coordination Site and Dual Beta-q114 Rotamer Conformation at 1.60 Angstrom Resolution
161. 7kh6: 1.45 Angstrom Resolution Internal Aldimine Crystal Structure of The BETA-Q114A Mutant of Tryptophansynthase in Complex with N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Enzyme Alpha-site and Cesium Ion at The Metal Coordination Site
162. 7ki7: The External Aldimine Crystal Structure of The BETA-K167T Mutant Tryptophan Synthase at 1.75 Angstrom Resolution in Complex with N- (4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Enzyme Alpha-site and Cesium Ion at The Metal Coordination Site
163. 7kmc: The Internal Aldimine Crystal Structure of The BETA-K167T Mutant Tryptophan Synthase at 1.50 Angstrom Resolution with Cesium Ion at The Metal Coordination Site
164. 7kq9: The Aminoacrylate Form of The BETA-Q114A Mutant Tryptophan Synthase at 1.50 Angstrom Resolution with Cesium Ion at The Metal Coordination Site
165. 7kqf: The Internal Aldimine Form of The Wild-type Tryptophan Synthase from Salmonella in Complex with Inhibitor N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Enzyme Alpha-site and Cesium Ion at The Metal Coordination Site at 1.47 Angstrom Resolution
166. 7ku9: The Internal Aldimine Form of The Wild-type Salmonella Typhimurium Tryptophan Synthase with Sodium Ion at The Metal Coordination Site, Two Molecules of F6F Inhibitor at The Enzyme Alpha-site and Another F6F Molecule at The Enzyme Beta-site at 1.40 Angstrom Resolution
167. 7kwv: The Aminoacrylate Form of The Wild-type Salmonella Typhimurium Tryptophan Synthase in Complex with Inhibitor N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Enzyme Alpha-site and Cesium Ion at The Metal Coordination Site at 1.30 Angstrom Resolution
168. 7kxc: The Aminoacrylate Form of The Wild-type Salmonella Typhimurium Tryptophan Synthase in Complex with Inhibitor N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Enzyme Alpha-site, Sodium Ion at The Metal Coordination Site and Benzimidazole (bzi) at The Enzyme Beta-site at 1.30 Angstrom Resolution. One of The Beta-q114 Rotamer Conformations Allows a Hydrogen Bond to Form with The Plp Oxygen at The Position 3 in The Ring
169. 7kyt: The Aminoacrylate Form of The Wild-type Salmonella Typhimurium Tryptophan Synthase in Complex with Inhibitor N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Enzyme Alpha-site, Cesium Ion at The Metal Coordination Site and Benzimidazole (bzi) at The Enzyme Beta-site at 1.35 Angstrom Resolution
170. 7l03: The Aminoacrylate Form of The Wild-type Salmonella Typhimurium Tryptophan Synthase in Complex with Inhibitor N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Enzyme Alpha-site and Sodium Ion at The Metal Coordination Site at 1.60 Angstrom Resolution. Three Water Molecules Are close to The Amynoacrylate at The Enzyme Beta-site
171. 7l1h: The Aminoacrylate Form of The Wild-type Salmonella Typhimurium Tryptophan Synthase in Complex with Inhibitor N-(4'- Trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at The Enzyme Alpha-site and Cesium Ion at The Metal Coordination Site at 1.50 Angstrom Resolution. Three Water Molecules Are close to The Amynoacrylate at The Enzyme Beta-site
172. 7l47: The Internal Aldimine Form of The BETA-K167T Mutant Tryptophan Synthase from Salmonella at 1.55 Angstrom Resolution with Cesium Ion at The Metal Coordination Site
173. 7l4d: The Internal Aldimine Form of The Wild-type Salmonella Typhimurium Tryptophan Synthase with Cesium Ion at The Metal Coordination Site at 1.60 Angstrom Resolution
174. 7l5h: The External Aldimine Form of The Wild-type Salmonella Typhimurium Tryptophan Synthase at 1.80 Angstrom Resolution with Cesium Ion at The Metal Coordination Site
175. 7mt4: Crystal Structure of Tryptophan Synthase in Complex with F9, Nh4+, Ph7.8 - Alpha Aminoacrylate Form - E(a-a)
176. 7mt5: Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, Ph7.8 - Alpha Aminoacrylate Form - E(a-a)
177. 7mt6: Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, Benzimidazole, Ph7.8 - Alpha Aminoacrylate Form - E(a-a)(bzi)