EC 4.2.99.18 - DNA- (apurinic or apyrimidinic site) 5'- phosphomonoester- lyase (DNA- (apurinic or apyrimidinic site) lyase)

3D structures of EC 4.2.99.18 - DNA-(apurinic or apyrimidinic site) lyase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1bix: The Crystal Structure of The Human Dna Repair Endonuclease Hap1 Suggests The Recognition of Extra-helical Deoxyribose at Dna Abasic Sites
2. 1cqg: High Resolution Solution Nmr Structure of Mixed Disulfide Intermediate between Human Thioredoxin (C35A, C62A, C69A, C73A) Mutant and a 13 Residue Peptide Comprising Its Target Site in Human Ref-1 (residues 59-71 of The P50 Subunit of Nfkb), Nmr, 31 Structures
3. 1cqh: High Resolution Solution Nmr Structure of Mixed Disulfide Intermediate between Human Thioredoxin (C35A, C62A, C69A, C73A) Mutant and a 13 Residue Peptide Comprising Its Target Site in Human Ref-1 (residues 59-71 of The P50 Subunit of Nfkb), Nmr, Minimized Average Structure
4. 1de8: Human Apurinic/apyrimidinic Endonuclease-1 (ape1) Bound to Abasic Dna
5. 1de9: Human Ape1 Endonuclease with Bound Abasic Dna and Mn2+ Ion
6. 1dew: Crystal Structure of Human Ape1 Bound to Abasic Dna
7. 1e9n: A Second Divalent Metal Ion in The Active Site of a New Crystal Form of Human Apurinic/apyrimidinic Endonuclease, Ape1, and Its Implications for The Catalytic Mechanism
8. 1hd7: A Second Divalent Metal Ion in The Active Site of a New Crystal Form of Human Apurinic/apyridinimic Endonuclease, Ape1, and Its Implications for The Catalytic Mechanism
9. 1n39: Structural and Biochemical Exploration of a Critical Amino Acid in Human 8-oxoguanine Glycosylase
10. 1n3a: Structural and Biochemical Exploration of a Critical Amino Acid in Human 8-oxoguanine Glycosylase
11. 3ktu: Structure of Human 8-oxoguanine Glycosylase 1 Bound to Fluorninated Oxog-containing Dna
12. 3knt: Crystal Structure of Methanocaldococcus Jannaschii 8- Oxoguanine Glycosylase/lyase in Complex with 15mer Dna Containing 8-oxoguanine
13. 3jr5: Mutm Lesion Recognition Control Complex with N174C Crosslinking Site
14. 3jr4: Mutm Interrogating an Extrahelical G
15. 3ih7: Crystal Structure of Catalytically Active Human 8-oxoguanine Glycosylase Distally Crosslinked to Guanine-containing Dna
16. 3i0x: Crystal Structure of Clostridium Acetobutylicum 8-oxoguanine Glycosylase/lyase in Complex with Dsdna Containing Adenine opposite to 8-oxog
17. 3i0w: Crystal Structure of Clostridium Acetobutylicum 8-oxoguanine Glycosylase/lyase in Complex with Dsdna Containing Cytosine opposite to 8-oxog
18. 3gq5: Sequence-matched Mutm Interrogation Complex 5 (ic5)
19. 3gq4: Sequence-matched Mutm Lesion Recognition Complex 5 (lrc5)
20. 3gq3: Mutm Encountering an Intrahelical 8-oxoguanine (oxog) Lesion in Ec5-loop Deletion Complex
21. 3gpy: Sequence-matched Mutm Lesion Recognition Complex 3 (lrc3)
22. 3gpx: Sequence-matched Mutm Interrogation Complex 4 (ic4)
23. 3gpu: Mutm Encountering an Intrahelical 8-oxoguanine (oxog) Lesion in Ec4-loop Deletion Complex
24. 3gpp: Mutm Encountering an Intrahelical 8-oxoguanine (oxog) Lesion in EC3-T224P Complex
25. 3gp1: Mutm Encountering an Intrahelical 8-oxoguanine (oxog) Lesion in EC3-V222P Complex
26. 3go8: Mutm Encountering an Intrahelical 8-oxoguanine (oxog) Lesion in Ec3-loop Deletion Complex
27. 3fhg: Crystal Structure of Sulfolobus Solfataricus 8-oxoguanine Dna Glycosylase (ssogg)
28. 3fhf: Crystal Structure of Methanocaldococcus Jannaschii 8- Oxoguanine Dna Glycosylase (mjogg)
29. 3f10: Crystal Structure of Clostridium Acetobutylicum 8- Oxoguanine Dna Glycosylase in Complex with 8-oxoguanosine
30. 3f0z: Crystal Structure of Clostridium Acetobutylicum 8- Oxoguanine Glycosylase/lyase in Its Apo-form
31. 3c58: Crystal Structure of a Complex between The Wild-type Lactococcus Lactis Fpg (mutm) and a N7-benzyl-fapy-dg Containing Dna
32. 2voa: Structure of an Ap Endonuclease from Archaeoglobus Fulgidus
33. 6zxh: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State H2
34. 7k5i: Sars-cov-2 Nsp1 in Complex with Human 40s Ribosome
35. 7jqc: Sars-cov-2 Nsp1, Crpv Ires and Rabbit 40s Ribosome Complex
36. 7jqb: Sars-cov-2 Nsp1 and Rabbit 40s Ribosome Complex
37. 7jl5: Crystal Structure of Human Neil3 Tandem Zinc Finger Grf Domains
38. 2abk: Refinement of The Native Structure of Endonuclease III to a Resolution of 1.85 Angstrom
39. 6zxg: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State H1
40. 6zxf: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State G
41. 6zxe: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State F2
42. 6zxd: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State F1
43. 6zvh: Edf1-ribosome Complex
44. 6zol: Sars-cov-2-nsp1-40s Complex, Focused on Head
45. 6zoj: Sars-cov-2-nsp1-40s Complex, Composite Map
46. 6zn5: Sars-cov-2 Nsp1 Bound to a Pre-40s-like Ribosome Complex - State 2
47. 6zmt: Sars-cov-2 Nsp1 Bound to a Pre-40s-like Ribosome Complex
48. 6zlw: Sars-cov-2 Nsp1 Bound to The Human 40s Ribosomal Subunit
49. 2oq4: Crystal Structure of The Dna Repair Enzyme Endonuclease- VIII (nei) from E. Coli (E2Q) in Complex with Ap-site Containing Dna Substrate
50. 2opf: Crystal Structure of The Dna Repair Enzyme Endonuclease- VIII (nei) from E. Coli (R252A) in Complex with Ap-site Containing Dna Substrate
51. 6ybs: Structure of a Human 48s Translational Initiation Complex - Head
52. 6bow: Human Ape1 Substrate Complex with an T/t Mismatch Adjacent The Thf
53. 6bov: Human Ape1 Substrate Complex with an A/g Mismatch Adjacent The Thf
54. 6bou: Human Ape1 Substrate Complex with an T/c Mismatch Adjacent The Thf
55. 6bot: Human Ape1 Substrate Complex with an C/c Mismatch Adjacent The Thf
56. 6bos: Human Ape1 Substrate Complex with an A/c Mismatch Adjacent The Thf
57. 6bor: Human Ape1 Substrate Complex with an G/g Mismatch Adjacent The Thf
58. 6boq: Human Ape1 Substrate Complex with an A/a Mismatch Adjacent The Thf
59. 2o3h: Crystal Structure of The Human C65A Ape
60. 2ea0: Crystal Structure of The Dna Repair Enzyme Endonuclease- VIII (nei) from E. Coli in Complex with Ap-site Containing Dna Substrate
61. 2noz: Structure of Q315F Human 8-oxoguanine Glycosylase Distal Crosslink to 8-oxoguanine Dna
62. 2nol: Structure of Catalytically Inactive Human 8-oxoguanine Glycosylase Distal Crosslink to Oxog Dna
63. 2noi: Structure of G42A Human 8-oxoguanine Glycosylase Crosslinked to Undamaged G-containing Dna
64. 2noh: Structure of Catalytically Inactive Q315A Human 8- Oxoguanine Glycosylase Complexed to 8-oxoguanine Dna
65. 2nof: Structure of Q315F Human 8-oxoguanine Glycosylase Proximal Crosslink to 8-oxoguanine Dna
66. 2noe: Structure of Catalytically Inactive G42A Human 8-oxoguanine Glycosylase Complexed to 8-oxoguanine Dna
67. 2nob: Structure of Catalytically Inactive H270A Human 8- Oxoguanine Glycosylase Crosslinked to 8-oxoguanine Dna
68. 2i5w: Structure of Hogg1 Crosslinked to Dna Sampling a Normal G Adjacent to an Oxog
69. 2isi: Crystal Structure of Ape1 from Homo Sapiens in a New Crystal Form Complexed with a Ligand
70. 2j63: Crystal Structure of Ap Endonuclease Lmap from Leishmania Major
71. 6w13: Human 8-oxoguanine Glycosylase Interrogating Fully Intrahelical Oxog Lesion Dna
72. 6w0r: Human 8-oxoguanine Glycosylase Interrogating Fully Intrahelical Undamaged Dna
73. 6w0m: Human 8-oxoguanine Glycosylase Crosslinked with Oxog Lesion Containing Dna
74. 6tc9: Crystal Structure of Mutm from Neisseria Meningitidis
75. 6tc6: Crystal Structure of Mutm from Neisseria Meningitidis
76. 2kqb: First Pbz Domain of Human Aplf Protein
77. 2kqc: Second Pbz Domain of Human Aplf Protein
78. 2kqd: First Pbz Domain of Human Aplf Protein in Complex with Ribofuranosyladenosine
79. 2kqe: Second Pbz Domain of Human Aplf Protein in Complex with Ribofuranosyladenosine
80. 6l94: The Structure of The Dioxygenase Abh1 from Mouse
81. 2xhi: Separation-of-function Mutants Unravel The Dual Reaction Mode of Human 8-oxoguanine Dna Glycosylase
82. 6w4t: Ape1 Y269A Phosphorothioate Substrate Complex with Abasic Dna
83. 6w4i: Ape1 Y269A Product Complex with Abasic Dna
84. 6w43: Ape1 Ap-endonuclease Product Complex R237C
85. 6w3u: Ape1 Exonuclease Substrate Complex R237C
86. 6w3q: Ape1 Exonuclease Substrate Complex L104R
87. 6w3n: Ape1 Exonuclease Substrate Complex D148E
88. 6w3l: Ape1 Exonuclease Substrate Complex Wild-type
89. 6w2p: Ape1 Endonuclease Product Complex L104R
90. 6w0q: Ape1 Endonuclease Product Complex D148E
91. 3n0u: Crystal Structure of Tm1821, The 8-oxoguanine Dna Glycosylase of Thermotoga Maritima
92. 6wcd: Crystal Structure of Xenopus Laevis Ape2 Catalytic Domain
93. 6rp7: The Crystal Structure of a Complex between The Llfpg Protein, a Thf- Dna and an Inhibitor
94. 6rok: The Crystal Structure of a Complex between The Llfpg Protein, a Thf- Dna and an Inhibitor
95. 6ro2: The Crystal Structure of a Complex between The Llfpg Protein, a Thf- Dna and an Inhibitor
96. 6rnr: The Crystal Structure of a Complex between The Llfpg Protein, a Thf- Dna and an Inhibitor
97. 6rno: Crystal Structure of a Complex between The Llfpg Protein, a Thf-dna and an Inhibitor
98. 6rnm: Crystal Structure of a Complex between The Llfpg Protein, a Thf-dna and an Inhibitor
99. 6p94: Human Ape1 C65A Ap-endonuclease Product Complex
100. 6p93: Human Ape1 K98A Ap-endonuclease Product Complex
101. 2xzu: Crystal Structure of a Complex between The Wild-type Lactococcus Lactis Fpg (mutm) and an Oxidized Pyrimidine Containing Dna at 310k
102. 3u8u: Crystal Structure of Human Apurinic/apyridinimic Endonuclease, Ape1 in a New Crystal Form
103. 3vk7: Crystal Structure of Dna-glycosylase Bound to Dna Containing 5- Hydroxyuracil
104. 3vk8: Crystal Structure of Dna-glycosylase Bound to Dna Containing Thymine Glycol
105. 3sas: Mutm Slanted Complex 4 with R112A Mutation
106. 3sat: Mutm Slanted Complex 6 with R112A Mutation
107. 3sau: Mutm Interrogation Complex 6
108. 3sav: Mutm Slanted Complex 8
109. 3saw: Mutm Slanted Complex 8 with R112A Mutation
110. 6mko: Crystallographic Solvent Mapping Analysis of Glycerol Bound to Ape1
111. 6mkm: Crystallographic Solvent Mapping Analysis of Dmso/tris Bound to Ape1
112. 6mkk: Crystallographic Solvent Mapping Analysis of Dmso/mg Bound to Ape1
113. 6mk3: Crystallographic Solvent Mapping Analysis of Dmso Bound to Ape1
114. 4iem: Human Apurinic/apyrimidinic Endonuclease (ape1) with Product Dna and Mg2+
115. 6h0s: Crystal Structure of The Complex between The Lactococcus Lactis Fpg Mutant G226P and a Fapy-dg Containing Dna
116. 6g5i: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State R
117. 6g5h: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - Mature
118. 6g53: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State E
119. 6g51: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State D
120. 6g40: Structure of The Mouse 8-oxoguanine Dna Glycosylase Mogg1 in Complex with Ligand Th9525
121. 6g3y: Structure of The Mouse 8-oxoguanine Dna Glycosylase Mogg1 in Complex with Ligand Th5675
122. 6g3x: Native Structure of The Mouse 8-oxoguanine Dna Glycosylase Mogg1
123. 6fl1: Crystal Structure of The Complex between The Lactococcus Lactis Fpg Mutant T221P and a Fapy-dg Containing Dna
124. 6fbu: Crystal Structure of The Dna Repair Enzyme Endonuclease-viii (nei) from E. Coli (E2Q) in Complex with Ap-site Containing Dna Substrate
125. 6erf: Complex of Aplf Factor and Ku Heterodimer Bound to Dna
126. 4lnd: Crystal Structure of Human Apurinic/apyrimidinic Endonuclease 1 with Essential Mg2+ Cofactor
127. 4mb7: Crystal Structure of a Viral Dna Glycosylase
128. 4nrv: Crystal Structure of Non-edited Human Neil1
129. 4nrw: MVNEI1-G86D
130. 4qh9: Crystal Structure of Mn2+ Bound Human Ape1
131. 4qhd: Crystal Structure of Apo Human Ape1
132. 4qhe: Crystal Structure of Mg2+ Bound Human Ape1
133. 5wn5: Ape1 Exonuclease Substrate Complex with a C/t Mismatch and Mn2+
134. 5wn4: Ape1 Exonuclease Substrate Complex with a C/t Mismatch
135. 5wn3: Ape1 F266A Exonuclease Substrate Complex with a C/t Mismatch
136. 5wn2: Ape1 Exonuclease Substrate Complex with Phosphoglycolate
137. 5wn1: Ape1 Exonuclease Product Complex
138. 5wn0: Ape1 Exonuclease Substrate Complex with a C/g Match
139. 5w7y: Crystal Structure of Fha Domain of Human Aplf in Complex with Xrcc1 Monophosphorylated Mutated Peptide
140. 5w7x: Crystal Structure of Fha Domain of Human Aplf in Complex with Xrcc1 Bisphospho Peptide
141. 5w7w: Crystal Structure of Fha Domain of Human Aplf
142. 6ima: Crystal Structure of Alkbh1 without Alpha-1 (n37-c369)
143. 6imc: Crystal Structure of Alkbh1 in Complex with Mn(ii) and N-oxalylglycine
144. 4pii: Crystal Structure of Hypothetical Protein Pf0907 from Pyrococcus Furiosus Solved by Sulfur Sad Using Swiss Light Source Data
145. 5u6z: Crystal Structure of Xenopus Laevis Apex2 C-terminal Znf-grf Domain
146. 5oa3: Human 40S-EIF2D-RE-INITIATION Complex
147. 6lwa: Crystal Structure of Human NEIL1(P2G, E3Q, K242) Bound to Duplex Dna Containing 5-hydroxyuracil (5-ohu)
148. 5ity: Crystal Structure of Human NEIL1(P2G) Bound to Duplex Dna Containing Thymine Glycol
149. 5itx: Crystal Structure of Human NEIL1(P2G R242K) Bound to Duplex Dna Containing Thymine Glycol
150. 5itu: Crystal Structure of Human Neil1(242k) Bound to Duplex Dna Containing Thf
151. 5itt: Crystal Structure of Human Neil1 Bound to Duplex Dna Containing Thf
152. 5itr: Crystal Structure of Human NEIL1(P2G) Bound to Duplex Dna Containing Thf
153. 5itq: Crystal Structure of Human Neil1, Free Protein
154. 5flx: Mammalian 40s Hcv-ires Complex
155. 5e50: Aplf/xrcc4 Complex
156. 5dg0: Human Ape1 Phosphorothioate Substrate Complex with Mn2+
157. 5dfj: Human Ape1 E96Q/D210N Mismatch Substrate Complex
158. 5dfi: Human Ape1 Phosphorothioate Substrate Complex
159. 5dfh: Human Ape1 Mismatch Product Complex
160. 5dff: Human Ape1 Product Complex
161. 5cfg: C2 Crystal Form of Ape1 with Mg2+
162. 5an4: Crystal Structure of The Human 8-oxoguanine Glycosylase (ogg1) Processed with The Crystaldirect Automated Mounting and Cryo-cooling Technology
163. 4unf: Crystal Structure of Deinococcus Radiodurans Endonuclease Iii-1
164. 4uob: Crystal Structure of Deinococcus Radiodurans Endonuclease Iii-3
165. 6zuo: Human Rio1(kd)-stha Late Pre-40s Particle, Structural State a (pre 18s Rrna Cleavage)
166. 6zv6: Human Rio1(kd)-stha Late Pre-40s Particle, Structural State B (post 18s Rrna Cleavage)
167. 6lwb: Crystal Structure of Human NEIL1(P2G, E3Q, R242) Bound to Duplex Dna Containing 5-hydroxyuracil (5-ohu)
168. 6lwc: Crystal Structure of Human NEIL1(P2G, E3Q, K242) Bound to Duplex Dna Containing Spiroiminodihydantoin (sp)
169. 6lwd: Crystal Structure of Human NEIL1(P2G, E3Q, R242) Bound to Duplex Dna Containing Spiroiminodihydantoin (sp)
170. 6lwf: Crystal Structure of Human NEIL1(P2G, E3Q, K242) Bound to Duplex Dna Containing Guanidinohydantoin (gh)
171. 6lwg: Crystal Structure of Human NEIL1(P2G, E3Q, R242) Bound to Duplex Dna Containing Guanidinohydantoin (gh)
172. 6lwh: Crystal Structure of Human NEIL1(P2G, E3Q, K242) Bound to Duplex Dna Containing Dihydrothymine (dht)
173. 6lwi: Crystal Structure of Human NEIL1(P2G, E3Q, R242) Bound to Duplex Dna Containing Dihydrothymine (dht)
174. 6lwj: Crystal Structure of Human NEIL1(P2G, E3Q, K242) Bound to Duplex Dna Containing Dihydrouracil (dhu)
175. 6lwk: Crystal Structure of Human NEIL1(P2G, E3Q, R242) Bound to Duplex Dna Containing Dihydrouracil (dhu)
176. 6lwl: Crystal Structure of Human Neil1(r242) Bound to Duplex Dna Containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
177. 6lwm: Crystal Structure of Human Neil1(k242) Bound to Duplex Dna Containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
178. 6lwn: Crystal Structure of Human Neil1(r242, G249P) Bound to Duplex Dna Containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
179. 6lwo: Crystal Structure of Human Neil1(r242, Y244H) Bound to Duplex Dna Containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
180. 6lwp: Crystal Structure of Human Neil1(r242, Y244R) Bound to Duplex Dna Containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
181. 6lwq: Crystal Structure of Human Neil1(r242) Bound to Duplex Dna Containing a C:t Mismatch
182. 6lwr: Crystal Structure of Human Neil1(k242) Bound to Duplex Dna Containing a Cleaved C:t Mismatch
183. 7lpg: Ape1 Product Complex with Abasic Ribonucleotide Dna
184. 7lph: Ape1 Mn-bound Product Complex with Abasic Ribonucleotide Dna
185. 7lpi: Ape1 Phosphorothioate Substrate Complex with Abasic Ribonucleotide Dna
186. 7lpj: Ape1 Mn-bound Phosphorothioate Substrate Complex with Abasic Ribonucleotide Dna
187. 6yn1: Crystal Structure of Histone Chaperone Aplf Acidic Domain Bound to The Histone H2A-H2B-H3-H4 Octamer
188. 7rds: Structure of Human Nthl1
189. 7rdt: Structure of Human Nthl1 - Linker 1 Chimera