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enzyme (lysozyme)

 
Enzymes
  Enzyme classes:
  EC 1: Oxidoreductases
  EC 2: Transferases
  EC 3: Hydrolases
  EC 4: Lyases
    EC 4.1
    EC 4.2
      EC 4.2.1
      EC 4.2.2
      EC 4.2.3
      EC 4.2.99
        EC 4.2.99.1
        EC 4.2.99.2
        EC 4.2.99.3
        EC 4.2.99.4
        EC 4.2.99.5
        EC 4.2.99.6
        EC 4.2.99.7
        EC 4.2.99.8
        EC 4.2.99.9
        EC 4.2.99.10
        EC 4.2.99.11
        EC 4.2.99.12
        EC 4.2.99.13
        EC 4.2.99.14
        EC 4.2.99.15
        EC 4.2.99.16
        EC 4.2.99.17
        EC 4.2.99.18
        EC 4.2.99.19
    EC 4.3
    EC 4.4
    EC 4.5
    EC 4.6
    EC 4.99
  EC 5: Isomerases
  EC 6: Ligases
  General information:
  Catalytic mechanism
  Enzyme kinetics
  Inhibitors
  Enzymes in industry

EC 4.2.99.18 - DNA- (apurinic or apyrimidinic site) 5'- phosphomonoester- lyase (DNA- (apurinic or apyrimidinic site) lyase)



3D structures of EC 4.2.99.18 - DNA-(apurinic or apyrimidinic site) lyase in Protein Data Bank

updated: 6 January 2022, 2:15

In total: 189 PDB structures of EC 4.2.99.18 - DNA-(apurinic or apyrimidinic site) lyase:
  1. 1bix: The Crystal Structure of The Human Dna Repair Endonuclease Hap1 Suggests The Recognition of Extra-helical Deoxyribose at Dna Abasic Sites
  2. 1cqg: High Resolution Solution Nmr Structure of Mixed Disulfide Intermediate between Human Thioredoxin (C35A, C62A, C69A, C73A) Mutant and a 13 Residue Peptide Comprising Its Target Site in Human Ref-1 (residues 59-71 of The P50 Subunit of Nfkb), Nmr, 31 Structures
  3. 1cqh: High Resolution Solution Nmr Structure of Mixed Disulfide Intermediate between Human Thioredoxin (C35A, C62A, C69A, C73A) Mutant and a 13 Residue Peptide Comprising Its Target Site in Human Ref-1 (residues 59-71 of The P50 Subunit of Nfkb), Nmr, Minimized Average Structure
  4. 1de8: Human Apurinic/apyrimidinic Endonuclease-1 (ape1) Bound to Abasic Dna
  5. 1de9: Human Ape1 Endonuclease with Bound Abasic Dna and Mn2+ Ion
  6. 1dew: Crystal Structure of Human Ape1 Bound to Abasic Dna
  7. 1e9n: A Second Divalent Metal Ion in The Active Site of a New Crystal Form of Human Apurinic/apyrimidinic Endonuclease, Ape1, and Its Implications for The Catalytic Mechanism
  8. 1hd7: A Second Divalent Metal Ion in The Active Site of a New Crystal Form of Human Apurinic/apyridinimic Endonuclease, Ape1, and Its Implications for The Catalytic Mechanism
  9. 1n39: Structural and Biochemical Exploration of a Critical Amino Acid in Human 8-oxoguanine Glycosylase
  10. 1n3a: Structural and Biochemical Exploration of a Critical Amino Acid in Human 8-oxoguanine Glycosylase
  11. 3ktu: Structure of Human 8-oxoguanine Glycosylase 1 Bound to Fluorninated Oxog-containing Dna
  12. 3knt: Crystal Structure of Methanocaldococcus Jannaschii 8- Oxoguanine Glycosylase/lyase in Complex with 15mer Dna Containing 8-oxoguanine
  13. 3jr5: Mutm Lesion Recognition Control Complex with N174C Crosslinking Site
  14. 3jr4: Mutm Interrogating an Extrahelical G
  15. 3ih7: Crystal Structure of Catalytically Active Human 8-oxoguanine Glycosylase Distally Crosslinked to Guanine-containing Dna
  16. 3i0x: Crystal Structure of Clostridium Acetobutylicum 8-oxoguanine Glycosylase/lyase in Complex with Dsdna Containing Adenine opposite to 8-oxog
  17. 3i0w: Crystal Structure of Clostridium Acetobutylicum 8-oxoguanine Glycosylase/lyase in Complex with Dsdna Containing Cytosine opposite to 8-oxog
  18. 3gq5: Sequence-matched Mutm Interrogation Complex 5 (ic5)
  19. 3gq4: Sequence-matched Mutm Lesion Recognition Complex 5 (lrc5)
  20. 3gq3: Mutm Encountering an Intrahelical 8-oxoguanine (oxog) Lesion in Ec5-loop Deletion Complex
  21. 3gpy: Sequence-matched Mutm Lesion Recognition Complex 3 (lrc3)
  22. 3gpx: Sequence-matched Mutm Interrogation Complex 4 (ic4)
  23. 3gpu: Mutm Encountering an Intrahelical 8-oxoguanine (oxog) Lesion in Ec4-loop Deletion Complex
  24. 3gpp: Mutm Encountering an Intrahelical 8-oxoguanine (oxog) Lesion in EC3-T224P Complex
  25. 3gp1: Mutm Encountering an Intrahelical 8-oxoguanine (oxog) Lesion in EC3-V222P Complex
  26. 3go8: Mutm Encountering an Intrahelical 8-oxoguanine (oxog) Lesion in Ec3-loop Deletion Complex
  27. 3fhg: Crystal Structure of Sulfolobus Solfataricus 8-oxoguanine Dna Glycosylase (ssogg)
  28. 3fhf: Crystal Structure of Methanocaldococcus Jannaschii 8- Oxoguanine Dna Glycosylase (mjogg)
  29. 3f10: Crystal Structure of Clostridium Acetobutylicum 8- Oxoguanine Dna Glycosylase in Complex with 8-oxoguanosine
  30. 3f0z: Crystal Structure of Clostridium Acetobutylicum 8- Oxoguanine Glycosylase/lyase in Its Apo-form
  31. 3c58: Crystal Structure of a Complex between The Wild-type Lactococcus Lactis Fpg (mutm) and a N7-benzyl-fapy-dg Containing Dna
  32. 2voa: Structure of an Ap Endonuclease from Archaeoglobus Fulgidus
  33. 6zxh: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State H2
  34. 7k5i: Sars-cov-2 Nsp1 in Complex with Human 40s Ribosome
  35. 7jqc: Sars-cov-2 Nsp1, Crpv Ires and Rabbit 40s Ribosome Complex
  36. 7jqb: Sars-cov-2 Nsp1 and Rabbit 40s Ribosome Complex
  37. 7jl5: Crystal Structure of Human Neil3 Tandem Zinc Finger Grf Domains
  38. 2abk: Refinement of The Native Structure of Endonuclease III to a Resolution of 1.85 Angstrom
  39. 6zxg: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State H1
  40. 6zxf: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State G
  41. 6zxe: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State F2
  42. 6zxd: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State F1
  43. 6zvh: Edf1-ribosome Complex
  44. 6zol: Sars-cov-2-nsp1-40s Complex, Focused on Head
  45. 6zoj: Sars-cov-2-nsp1-40s Complex, Composite Map
  46. 6zn5: Sars-cov-2 Nsp1 Bound to a Pre-40s-like Ribosome Complex - State 2
  47. 6zmt: Sars-cov-2 Nsp1 Bound to a Pre-40s-like Ribosome Complex
  48. 6zlw: Sars-cov-2 Nsp1 Bound to The Human 40s Ribosomal Subunit
  49. 2oq4: Crystal Structure of The Dna Repair Enzyme Endonuclease- VIII (nei) from E. Coli (E2Q) in Complex with Ap-site Containing Dna Substrate
  50. 2opf: Crystal Structure of The Dna Repair Enzyme Endonuclease- VIII (nei) from E. Coli (R252A) in Complex with Ap-site Containing Dna Substrate
  51. 6ybs: Structure of a Human 48s Translational Initiation Complex - Head
  52. 6bow: Human Ape1 Substrate Complex with an T/t Mismatch Adjacent The Thf
  53. 6bov: Human Ape1 Substrate Complex with an A/g Mismatch Adjacent The Thf
  54. 6bou: Human Ape1 Substrate Complex with an T/c Mismatch Adjacent The Thf
  55. 6bot: Human Ape1 Substrate Complex with an C/c Mismatch Adjacent The Thf
  56. 6bos: Human Ape1 Substrate Complex with an A/c Mismatch Adjacent The Thf
  57. 6bor: Human Ape1 Substrate Complex with an G/g Mismatch Adjacent The Thf
  58. 6boq: Human Ape1 Substrate Complex with an A/a Mismatch Adjacent The Thf
  59. 2o3h: Crystal Structure of The Human C65A Ape
  60. 2ea0: Crystal Structure of The Dna Repair Enzyme Endonuclease- VIII (nei) from E. Coli in Complex with Ap-site Containing Dna Substrate
  61. 2noz: Structure of Q315F Human 8-oxoguanine Glycosylase Distal Crosslink to 8-oxoguanine Dna
  62. 2nol: Structure of Catalytically Inactive Human 8-oxoguanine Glycosylase Distal Crosslink to Oxog Dna
  63. 2noi: Structure of G42A Human 8-oxoguanine Glycosylase Crosslinked to Undamaged G-containing Dna
  64. 2noh: Structure of Catalytically Inactive Q315A Human 8- Oxoguanine Glycosylase Complexed to 8-oxoguanine Dna
  65. 2nof: Structure of Q315F Human 8-oxoguanine Glycosylase Proximal Crosslink to 8-oxoguanine Dna
  66. 2noe: Structure of Catalytically Inactive G42A Human 8-oxoguanine Glycosylase Complexed to 8-oxoguanine Dna
  67. 2nob: Structure of Catalytically Inactive H270A Human 8- Oxoguanine Glycosylase Crosslinked to 8-oxoguanine Dna
  68. 2i5w: Structure of Hogg1 Crosslinked to Dna Sampling a Normal G Adjacent to an Oxog
  69. 2isi: Crystal Structure of Ape1 from Homo Sapiens in a New Crystal Form Complexed with a Ligand
  70. 2j63: Crystal Structure of Ap Endonuclease Lmap from Leishmania Major
  71. 6w13: Human 8-oxoguanine Glycosylase Interrogating Fully Intrahelical Oxog Lesion Dna
  72. 6w0r: Human 8-oxoguanine Glycosylase Interrogating Fully Intrahelical Undamaged Dna
  73. 6w0m: Human 8-oxoguanine Glycosylase Crosslinked with Oxog Lesion Containing Dna
  74. 6tc9: Crystal Structure of Mutm from Neisseria Meningitidis
  75. 6tc6: Crystal Structure of Mutm from Neisseria Meningitidis
  76. 2kqb: First Pbz Domain of Human Aplf Protein
  77. 2kqc: Second Pbz Domain of Human Aplf Protein
  78. 2kqd: First Pbz Domain of Human Aplf Protein in Complex with Ribofuranosyladenosine
  79. 2kqe: Second Pbz Domain of Human Aplf Protein in Complex with Ribofuranosyladenosine
  80. 6l94: The Structure of The Dioxygenase Abh1 from Mouse
  81. 2xhi: Separation-of-function Mutants Unravel The Dual Reaction Mode of Human 8-oxoguanine Dna Glycosylase
  82. 6w4t: Ape1 Y269A Phosphorothioate Substrate Complex with Abasic Dna
  83. 6w4i: Ape1 Y269A Product Complex with Abasic Dna
  84. 6w43: Ape1 Ap-endonuclease Product Complex R237C
  85. 6w3u: Ape1 Exonuclease Substrate Complex R237C
  86. 6w3q: Ape1 Exonuclease Substrate Complex L104R
  87. 6w3n: Ape1 Exonuclease Substrate Complex D148E
  88. 6w3l: Ape1 Exonuclease Substrate Complex Wild-type
  89. 6w2p: Ape1 Endonuclease Product Complex L104R
  90. 6w0q: Ape1 Endonuclease Product Complex D148E
  91. 3n0u: Crystal Structure of Tm1821, The 8-oxoguanine Dna Glycosylase of Thermotoga Maritima
  92. 6wcd: Crystal Structure of Xenopus Laevis Ape2 Catalytic Domain
  93. 6rp7: The Crystal Structure of a Complex between The Llfpg Protein, a Thf- Dna and an Inhibitor
  94. 6rok: The Crystal Structure of a Complex between The Llfpg Protein, a Thf- Dna and an Inhibitor
  95. 6ro2: The Crystal Structure of a Complex between The Llfpg Protein, a Thf- Dna and an Inhibitor
  96. 6rnr: The Crystal Structure of a Complex between The Llfpg Protein, a Thf- Dna and an Inhibitor
  97. 6rno: Crystal Structure of a Complex between The Llfpg Protein, a Thf-dna and an Inhibitor
  98. 6rnm: Crystal Structure of a Complex between The Llfpg Protein, a Thf-dna and an Inhibitor
  99. 6p94: Human Ape1 C65A Ap-endonuclease Product Complex
  100. 6p93: Human Ape1 K98A Ap-endonuclease Product Complex
  101. 2xzu: Crystal Structure of a Complex between The Wild-type Lactococcus Lactis Fpg (mutm) and an Oxidized Pyrimidine Containing Dna at 310k
  102. 3u8u: Crystal Structure of Human Apurinic/apyridinimic Endonuclease, Ape1 in a New Crystal Form
  103. 3vk7: Crystal Structure of Dna-glycosylase Bound to Dna Containing 5- Hydroxyuracil
  104. 3vk8: Crystal Structure of Dna-glycosylase Bound to Dna Containing Thymine Glycol
  105. 3sas: Mutm Slanted Complex 4 with R112A Mutation
  106. 3sat: Mutm Slanted Complex 6 with R112A Mutation
  107. 3sau: Mutm Interrogation Complex 6
  108. 3sav: Mutm Slanted Complex 8
  109. 3saw: Mutm Slanted Complex 8 with R112A Mutation
  110. 6mko: Crystallographic Solvent Mapping Analysis of Glycerol Bound to Ape1
  111. 6mkm: Crystallographic Solvent Mapping Analysis of Dmso/tris Bound to Ape1
  112. 6mkk: Crystallographic Solvent Mapping Analysis of Dmso/mg Bound to Ape1
  113. 6mk3: Crystallographic Solvent Mapping Analysis of Dmso Bound to Ape1
  114. 4iem: Human Apurinic/apyrimidinic Endonuclease (ape1) with Product Dna and Mg2+
  115. 6h0s: Crystal Structure of The Complex between The Lactococcus Lactis Fpg Mutant G226P and a Fapy-dg Containing Dna
  116. 6g5i: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State R
  117. 6g5h: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - Mature
  118. 6g53: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State E
  119. 6g51: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State D
  120. 6g40: Structure of The Mouse 8-oxoguanine Dna Glycosylase Mogg1 in Complex with Ligand Th9525
  121. 6g3y: Structure of The Mouse 8-oxoguanine Dna Glycosylase Mogg1 in Complex with Ligand Th5675
  122. 6g3x: Native Structure of The Mouse 8-oxoguanine Dna Glycosylase Mogg1
  123. 6fl1: Crystal Structure of The Complex between The Lactococcus Lactis Fpg Mutant T221P and a Fapy-dg Containing Dna
  124. 6fbu: Crystal Structure of The Dna Repair Enzyme Endonuclease-viii (nei) from E. Coli (E2Q) in Complex with Ap-site Containing Dna Substrate
  125. 6erf: Complex of Aplf Factor and Ku Heterodimer Bound to Dna
  126. 4lnd: Crystal Structure of Human Apurinic/apyrimidinic Endonuclease 1 with Essential Mg2+ Cofactor
  127. 4mb7: Crystal Structure of a Viral Dna Glycosylase
  128. 4nrv: Crystal Structure of Non-edited Human Neil1
  129. 4nrw: MVNEI1-G86D
  130. 4qh9: Crystal Structure of Mn2+ Bound Human Ape1
  131. 4qhd: Crystal Structure of Apo Human Ape1
  132. 4qhe: Crystal Structure of Mg2+ Bound Human Ape1
  133. 5wn5: Ape1 Exonuclease Substrate Complex with a C/t Mismatch and Mn2+
  134. 5wn4: Ape1 Exonuclease Substrate Complex with a C/t Mismatch
  135. 5wn3: Ape1 F266A Exonuclease Substrate Complex with a C/t Mismatch
  136. 5wn2: Ape1 Exonuclease Substrate Complex with Phosphoglycolate
  137. 5wn1: Ape1 Exonuclease Product Complex
  138. 5wn0: Ape1 Exonuclease Substrate Complex with a C/g Match
  139. 5w7y: Crystal Structure of Fha Domain of Human Aplf in Complex with Xrcc1 Monophosphorylated Mutated Peptide
  140. 5w7x: Crystal Structure of Fha Domain of Human Aplf in Complex with Xrcc1 Bisphospho Peptide
  141. 5w7w: Crystal Structure of Fha Domain of Human Aplf
  142. 6ima: Crystal Structure of Alkbh1 without Alpha-1 (n37-c369)
  143. 6imc: Crystal Structure of Alkbh1 in Complex with Mn(ii) and N-oxalylglycine
  144. 4pii: Crystal Structure of Hypothetical Protein Pf0907 from Pyrococcus Furiosus Solved by Sulfur Sad Using Swiss Light Source Data
  145. 5u6z: Crystal Structure of Xenopus Laevis Apex2 C-terminal Znf-grf Domain
  146. 5oa3: Human 40S-EIF2D-RE-INITIATION Complex
  147. 6lwa: Crystal Structure of Human NEIL1(P2G, E3Q, K242) Bound to Duplex Dna Containing 5-hydroxyuracil (5-ohu)
  148. 5ity: Crystal Structure of Human NEIL1(P2G) Bound to Duplex Dna Containing Thymine Glycol
  149. 5itx: Crystal Structure of Human NEIL1(P2G R242K) Bound to Duplex Dna Containing Thymine Glycol
  150. 5itu: Crystal Structure of Human Neil1(242k) Bound to Duplex Dna Containing Thf
  151. 5itt: Crystal Structure of Human Neil1 Bound to Duplex Dna Containing Thf
  152. 5itr: Crystal Structure of Human NEIL1(P2G) Bound to Duplex Dna Containing Thf
  153. 5itq: Crystal Structure of Human Neil1, Free Protein
  154. 5flx: Mammalian 40s Hcv-ires Complex
  155. 5e50: Aplf/xrcc4 Complex
  156. 5dg0: Human Ape1 Phosphorothioate Substrate Complex with Mn2+
  157. 5dfj: Human Ape1 E96Q/D210N Mismatch Substrate Complex
  158. 5dfi: Human Ape1 Phosphorothioate Substrate Complex
  159. 5dfh: Human Ape1 Mismatch Product Complex
  160. 5dff: Human Ape1 Product Complex
  161. 5cfg: C2 Crystal Form of Ape1 with Mg2+
  162. 5an4: Crystal Structure of The Human 8-oxoguanine Glycosylase (ogg1) Processed with The Crystaldirect Automated Mounting and Cryo-cooling Technology
  163. 4unf: Crystal Structure of Deinococcus Radiodurans Endonuclease Iii-1
  164. 4uob: Crystal Structure of Deinococcus Radiodurans Endonuclease Iii-3
  165. 6zuo: Human Rio1(kd)-stha Late Pre-40s Particle, Structural State a (pre 18s Rrna Cleavage)
  166. 6zv6: Human Rio1(kd)-stha Late Pre-40s Particle, Structural State B (post 18s Rrna Cleavage)
  167. 6lwb: Crystal Structure of Human NEIL1(P2G, E3Q, R242) Bound to Duplex Dna Containing 5-hydroxyuracil (5-ohu)
  168. 6lwc: Crystal Structure of Human NEIL1(P2G, E3Q, K242) Bound to Duplex Dna Containing Spiroiminodihydantoin (sp)
  169. 6lwd: Crystal Structure of Human NEIL1(P2G, E3Q, R242) Bound to Duplex Dna Containing Spiroiminodihydantoin (sp)
  170. 6lwf: Crystal Structure of Human NEIL1(P2G, E3Q, K242) Bound to Duplex Dna Containing Guanidinohydantoin (gh)
  171. 6lwg: Crystal Structure of Human NEIL1(P2G, E3Q, R242) Bound to Duplex Dna Containing Guanidinohydantoin (gh)
  172. 6lwh: Crystal Structure of Human NEIL1(P2G, E3Q, K242) Bound to Duplex Dna Containing Dihydrothymine (dht)
  173. 6lwi: Crystal Structure of Human NEIL1(P2G, E3Q, R242) Bound to Duplex Dna Containing Dihydrothymine (dht)
  174. 6lwj: Crystal Structure of Human NEIL1(P2G, E3Q, K242) Bound to Duplex Dna Containing Dihydrouracil (dhu)
  175. 6lwk: Crystal Structure of Human NEIL1(P2G, E3Q, R242) Bound to Duplex Dna Containing Dihydrouracil (dhu)
  176. 6lwl: Crystal Structure of Human Neil1(r242) Bound to Duplex Dna Containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
  177. 6lwm: Crystal Structure of Human Neil1(k242) Bound to Duplex Dna Containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
  178. 6lwn: Crystal Structure of Human Neil1(r242, G249P) Bound to Duplex Dna Containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
  179. 6lwo: Crystal Structure of Human Neil1(r242, Y244H) Bound to Duplex Dna Containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
  180. 6lwp: Crystal Structure of Human Neil1(r242, Y244R) Bound to Duplex Dna Containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
  181. 6lwq: Crystal Structure of Human Neil1(r242) Bound to Duplex Dna Containing a C:t Mismatch
  182. 6lwr: Crystal Structure of Human Neil1(k242) Bound to Duplex Dna Containing a Cleaved C:t Mismatch
  183. 7lpg: Ape1 Product Complex with Abasic Ribonucleotide Dna
  184. 7lph: Ape1 Mn-bound Product Complex with Abasic Ribonucleotide Dna
  185. 7lpi: Ape1 Phosphorothioate Substrate Complex with Abasic Ribonucleotide Dna
  186. 7lpj: Ape1 Mn-bound Phosphorothioate Substrate Complex with Abasic Ribonucleotide Dna
  187. 6yn1: Crystal Structure of Histone Chaperone Aplf Acidic Domain Bound to The Histone H2A-H2B-H3-H4 Octamer
  188. 7rds: Structure of Human Nthl1
  189. 7rdt: Structure of Human Nthl1 - Linker 1 Chimera
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