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enzyme (lysozyme)

 
Enzymes
  Enzyme classes:
  EC 1: Oxidoreductases
  EC 2: Transferases
  EC 3: Hydrolases
  EC 4: Lyases
  EC 5: Isomerases
  EC 6: Ligases
    EC 6.1
      EC 6.1.1
        EC 6.1.1.1
        EC 6.1.1.2
        EC 6.1.1.3
        EC 6.1.1.4
        EC 6.1.1.5
        EC 6.1.1.6
        EC 6.1.1.7
        EC 6.1.1.8
        EC 6.1.1.9
        EC 6.1.1.10
        EC 6.1.1.11
        EC 6.1.1.12
        EC 6.1.1.13
        EC 6.1.1.14
        EC 6.1.1.15
        EC 6.1.1.16
        EC 6.1.1.17
        EC 6.1.1.18
        EC 6.1.1.19
        EC 6.1.1.20
        EC 6.1.1.21
        EC 6.1.1.22
        EC 6.1.1.23
        EC 6.1.1.24
        EC 6.1.1.25
        EC 6.1.1.26
    EC 6.2
    EC 6.3
    EC 6.4
    EC 6.5
    EC 6.6
  General information:
  Catalytic mechanism
  Enzyme kinetics
  Inhibitors
  Enzymes in industry

EC 6.1.1.10 - L- methionine:tRNA Met ligase (AMP- forming)



3D structures of EC 6.1.1.10 in Protein Data Bank

updated: 6 January 2022, 2:15

In total: 93 PDB structures of EC 6.1.1.10:
  1. 1a8h: Methionyl-trna Synthetase from Thermus Thermophilus
  2. 1f4l: Crystal Structure of The E.coli Methionyl-trna Synthetase Complexed with Methionine
  3. 1mea: Methionyl-trna Synthetase Zinc Binding Domain. 3d Structure and Homology with Rubredoxin and Gag Retroviral Proteins
  4. 1med: Methionyl-trna Synthetase Zinc Binding Domain. 3d Structure and Homology with Rubredoxin and Gag Retroviral Proteins
  5. 1mkh: C-terminal Domain of Methionyl-trna Synthetase from Pyrococcus Abyssi
  6. 3kfl: Leishmania Major Methionyl-trna Synthetase in Complex with Methionyladenylate and Pyrophosphate
  7. 1p7p: Methionyl-trna Synthetase from Escherichia Coli Complexed with Methionine Phosphonate
  8. 1pfu: Methionyl-trna Synthetase from Escherichia Coli Complexed with Methionine Phosphinate
  9. 1pfv: Methionyl-trna Synthetase from Escherichia Coli Complexed with Difluoromethionine
  10. 1pfw: Methionyl-trna Synthetase from Escherichia Coli Complexed with Trifluoromethionine
  11. 1pfy: Methionyl-trna Synthetase from Escherichia Coli Complexed with Methionyl Sulphamoyl Adenosine
  12. 1pg0: Methionyl-trna Synthetase from Escherichia Coli Complexed with Methioninyl Adenylate
  13. 1pg2: Methionyl-trna Synthetase from Escherichia Coli Complexed with Methionine and Adenosine
  14. 1qqt: Methionyl-trna Synthetase from Escherichia Coli
  15. 3h9c: Structure of Methionyl-trna Synthetase: Crystal Form 2
  16. 3h9b: Structure of a Mutant Methionyl-trna Synthetase with Modified Specificity Complexed with Azidonorleucine
  17. 3h99: Structure of a Mutant Methionyl-trna Synthetase with Modified Specificity Complexed with Methionine
  18. 3h97: Structure of a Mutant Methionyl-trna Synthetase with Modified Specificity
  19. 1rqg: Methionyl-trna Synthetase from Pyrococcus Abyssi
  20. 1woy: Crystal Structure of Methionyl Trna Synthetase Y225F Mutant from Thermus Thermophilus
  21. 2x1m: Crystal Structure of Mycobacterium Smegmatis Methionyl-trna Synthetase in Complex with Methionine
  22. 2x1l: Crystal Structure of Mycobacterium Smegmatis Methionyl-trna Synthetase in Complex with Methionine and Adenosine
  23. 2csx: Crystal Structure of Aquifex Aeolicus Methionyl-trna Synthetase Complexed with Trna(met)
  24. 2ct8: Crystal Structure of Aquifex Aeolicus Methionyl-trna Synthetase Complexed with Trna(met) and Methionyl-adenylate Anologue
  25. 2d54: Crystal Structure of Methionyl Trna Synthetase Y225A Mutant from Thermus Thermophilus
  26. 2d5b: Crystal Structure of Thermus Thermophilus Methionyl Trna Synthetase Y225F Mutant Obtained in The Presence of Peg6000
  27. 2djv: Solution Structures of The Whep-trs Domain of Human Methionyl-trna Synthetase
  28. 6ax8: Mycobacterium Tuberculosis Methionyl-trna Synthetase in Complex with Methionyl-adenylate
  29. 2hsn: Structural Basis of Yeast Aminoacyl-trna Synthetase Complex Formation Revealed by Crystal Structures of Two Binary Sub- Complexes
  30. 6swx: Leishmania Major Methionyl-trna Synthetase in Complex with an Allosteric Inhibitor
  31. 6spr: Structure of The Escherichia Coli Methionyl-trna Synthetase Variant Vi298 Complexed with Beta-methionine
  32. 6spq: Structure of The Escherichia Coli Methionyl-trna Synthetase Variant Vi298 Complexed with Methionine
  33. 6spp: Structure of The Escherichia Coli Methionyl-trna Synthetase Variant Vi298
  34. 6spo: Structure of The Escherichia Coli Methionyl-trna Synthetase Complexed with Methionine
  35. 6spn: Structure of The Escherichia Coli Methionyl-trna Synthetase Complexed with Beta-methionine
  36. 4dlp: Crystal Structure of Methionyl-trna Synthetase Metrs from Brucella Melitensis Bound to Selenomethionine
  37. 6mes: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor (chem 1907)
  38. 4eg1: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Substrate Methionine
  39. 4eg3: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Product Methionyl-adenylate
  40. 4eg4: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor Chem 1289
  41. 4eg5: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor Chem 1312
  42. 4eg6: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor Chem 1325
  43. 4eg7: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor Chem 1331
  44. 4eg8: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Compound Chem 89
  45. 4ega: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor Chem 1320
  46. 3vu8: Metionyl-trna Synthetase from Thermus Thermophilus Complexed with Methionyl-adenylate Analogue
  47. 6cml: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor (chem 2093)
  48. 4bl7: Crystal Structure of The Aimp3-mrs N-terminal Domain Complex in Different Space Group
  49. 4bvx: Crystal Structure of The Aimp3-mrs N-terminal Domain Complex with I3C
  50. 4bvy: Crystal Structure of The Aimp3-mrs N-terminal Domain Complex
  51. 4mvw: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-thiophen-3-ylurea (chem 1433)
  52. 4mvx: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-phenylurea (chem 1356)
  53. 4mvy: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-(3-hydroxyphenyl)urea (chem 1387)
  54. 4mw0: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-(2-hydroxyphenyl)urea (chem 1392)
  55. 4mw1: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-thiophen-3-ylurea (chem 1444)
  56. 4mw2: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-(3-{[5-chloro-2-hydroxy-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3- Thiophen-3-ylurea (chem 1472)
  57. 4mw4: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-{3-[(5-chloro-2-hydroxy-3-iodobenzyl)amino]propyl}-3-thiophen-3- Ylurea (chem 1473)
  58. 4mw5: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-phenylurea (chem 1415)
  59. 4mw6: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-(3-{[2-(benzyloxy)-5-chloro-3-(prop-2-en-1-yl)benzyl]amino}propyl)- 3-thiophen-3-ylurea (chem 1476)
  60. 4mw7: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-{3-[(5-chloro-2-ethoxy-3-iodobenzyl)amino]propyl}-3-thiophen-3- Ylurea (chem 1469)
  61. 4mw9: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-{3-[(3-ethynylbenzyl)amino]propyl}-3-thiophen-3-ylurea (chem 1478)
  62. 4mwb: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-(3-{[(2,5-dichlorothiophen-3-yl)methyl]amino}propyl)-3-thiophen-3- Ylurea (chem 1509)
  63. 4mwc: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-(3-{[(2-methyl-1-benzothiophen-3-yl)methyl]amino}propyl)-3- Thiophen-3-ylurea (chem 1540)
  64. 4mwd: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-thiophen-3-ylurea (chem 1433) and Atp Analog Amppcp
  65. 4mwe: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor 1-(3-{[5-chloro-3-(prop-2-en-1-yl)-2-(prop-2-en-1-yloxy) Benzyl]amino}propyl)-3-thiophen-3-ylurea (chem 1475)
  66. 5y6l: A Subcomplex Crystal Structure of Human Cytosolic Aspartyl-trna Synthetase and Heterotetrameric Glutathione Transferase-homology Domains in Multi-trna Synthetase Complex
  67. 5xgq: Crystal Structure of Apo Form (free-state) Mycobacterium Tuberculosis Methionyl-trna Synthetase
  68. 5xet: Crystal Structure of Mycobacterium Tuberculosis Methionyl-trna Synthetase Bound by Methionyl-adenylate (met-amp)
  69. 5v49: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor (chem 1917)
  70. 5urb: Crystal Structure of Methionyl-trna Synthetase (metrs) from Acinetobacter Baumannii with Bound L-methionine
  71. 5tqu: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor
  72. 5nfh: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with a Quinazolinone Inhibitor
  73. 5k0t: Crystal Structure of Methionyl-trna Synthetase Metrs from Brucella Melitensis in Complex with Inhibitor Chem 1415
  74. 5k0s: Crystal Structure of Methionyl-trna Synthetase Metrs from Brucella Melitensis in Complex with Inhibitor Chem 1312
  75. 5j5a: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor (chem 70786556)
  76. 5j59: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor (chem 1893)
  77. 5j58: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor (chem 1856)
  78. 5h34: Crystal Structure of The C-terminal Domain of Methionyl-trna Synthetase (metrs-c) in Nanoarchaeum Equitans
  79. 5goy: The Crystal Structure of Human Cytosolic Methionyl-trna Synthetase in Complex with Methionine
  80. 5gl7: Crystal Structure of a Truncated Human Cytosolic Methionyl-trna Synthetase
  81. 4zt7: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor N-[(4r)-6,8-dichloro-1,2,3,4-tetrahydroquinolin-4-yl]-n'-(5-fluoro- 3h-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (chem 1717)
  82. 4zt6: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor N-[(4r)-6,8-dichloro-3,4-dihydro-2h-chromen-4-yl]-n'-(5-fluoro-1h- Imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (chem 1709)
  83. 4zt5: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor (2s)-n-(3,5-dichlorobenzyl)-n'-(1h-imidazo[4,5-b]pyridin-2-yl)-2- Methylpropane-1,3-diamine (chem 1655)
  84. 4zt4: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitorn-(3,5-dichlorobenzyl)-2,2-difluoro-n'-(1h-imidazo[4,5- B]pyridin-2-yl)propane-1,3-diamine (chem 1708)
  85. 4zt3: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor N-(3,5-dichlorobenzyl)-n'-(5-fluoro-1h-imidazo[4,5-b]pyridin-2-yl) Propane-1,3-diamine (chem 1614)
  86. 4zt2: Trypanosoma Brucei Methionyl-trna Synthetase in Complex with Inhibitor N-(3,5-dichlorobenzyl)-n'-(1h-imidazo[4,5-b]pyridin-2-yl)propane-1,3- Diamine (chem 1575)
  87. 4py2: Crystal Structure of Methionyl-trna Synthetase Metrs from Brucella Melitensis in Complex with Inhibitor 1-{3-[(3,5-dichlorobenzyl) Amino]propyl}-3-thiophen-3-ylurea
  88. 4qrd: Structure of Methionyl-trna Synthetase in Complex with N-(1h- Benzimidazol-2-ylmethyl)-n'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)- 1,3,5-triazine-2,4-diamine
  89. 4qre: Structure of Methionyl-trna Synthetase in Complex with 1-(4-{4-[(1h- Benzimidazol-2-ylmethyl)amino]-6-(4,5-dimethoxy-2-methylphenoxy) Pyrimidin-2-yl}piperazin-1-yl)ethanone
  90. 6wq6: Xanthomonas Citri Methionyl-trna Synthetase in Complex with Methionine
  91. 6wqi: Xanthomonas Citri Methionyl-trna Synthetase (apo)
  92. 6wqs: Xanthomonas Citri Methionyl-trna Synthetase in Complex with Rep8839
  93. 6wqt: Xanthomonas Citri Methionyl-trna Synthetase in Complex with Rep3123
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