EC 6.1.1.4 - L- leucine:tRNA ^Leu ligase (AMP- forming)

3D structures of EC 6.1.1.4 in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1h3n: Leucyl-trna Synthetase from Thermus Thermophilus Complexed with a Sulphamoyl Analogue of Leucyl-adenylate
2. 3o0a: Crystal Structure of The Wild Type Cp1 Hydrolitic Domain from Aquifex Aeolicus Leucyl-trna
3. 1wkb: Crystal Structure of Leucyl-trna Synthetase from The Archaeon Pyrococcus Horikoshii Reveals a Novel Editing Domain Orientation
4. 1wz2: The Crystal Structure of Leucyl-trna Synthetase and Trna(leucine) Complex
5. 2wfd: Structure of The Human Cytosolic Leucyl-trna Synthetase Editing Domain
6. 7bzj: The Discovery of Benzhydrol-oxaborole Hybrid Derivatives as Leucyl- Trna Synthetase Inhibitors
7. 7ap2: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound LEUS7HMDDA
8. 2ajg: Crystal Structure of The Editing Domain of E. Coli Leucyl- Trna Synthetase
9. 2ajh: Crystal Structure of The Editing Domain of E. Coli Leucyl- Trna Synthetase Complexes with Methionine
10. 2aji: Crystal Structure of The Editing Domain of E. Coli Leucyl- Trna Synthetase Complexes with Isoleucine
11. 7a0p: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound 11i
12. 2bte: Thermus Thermophilus Leucyl-trna Synthetase Complexed with with a Trnaleu Transcript in The Post-editing Conformation and a Post-transfer Editing Substrate Analogue
13. 6ykx: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound 11j
14. 6ykw: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound 11h
15. 6ykv: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound 11g
16. 6yku: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound 11f
17. 6ykt: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound 11e
18. 6yks: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound 11d
19. 6ykq: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound 11c
20. 6yko: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound 11a
21. 6ykn: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound 11b
22. 6ykl: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound 11k
23. 6ykk: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with Compound 15
24. 2xgt: Asparaginyl-trna Synthetase from Brugia Malayi Complexed with The Sulphamoyl Analogue of Asparaginyl-adenylate
25. 2xti: Asparaginyl-trna Synthetase from Brugia Malayi Complexed with Atp:mg and L-asp-beta-noh Adenylate:ppi:mg
26. 6kr7: Crystal Structure of Methylated Human Leucyl-trna Synthetase, Leu-ams- Bound Form
27. 6kqy: Crystal Structure of Human Leucyl-trna Synthetase, Leucine-bound Form
28. 6kie: Crystal Structure of Human Leucyl-trna Synthetase, Leu-ams-bound Form
29. 6lr6: The Crystal Structure of Human Cytoplasmic Lrs
30. 6lpf: The Crystal Structure of Human Cytoplasmic Lrs
31. 3pz0: The Crystal Structure of Aaleurs-cp1
32. 3pz5: The Crystal Structure of Aaleurs-cp1-d20
33. 3pz6: The Crystal Structure of Glleurs-cp1
34. 6q8c: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with 5'-o-(n- (l-leucyl)-sulfamoyl)uridine
35. 6q8b: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with 5'-o-(n- (l-leucyl)-sulfamoyl)n3-methyluridine
36. 6q8a: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with 5'-o-(n- (l-leucyl)-sulfamoyl)cytidine
37. 6q89: Neisseria Gonorrhoeae Leucyl-trna Synthetase in Complex with The Intermediate Analog 5'-o-(n-(l-leucyl)-sulfamoyl)adenosine
38. 4aq7: Ternary Complex of E. Coli Leucyl-trna Synthetase, Trna(leu) and Leucyl-adenylate Analogue in The Aminoacylation Conformation
39. 4arc: Ternary Complex of E. Coli Leucyl-trna Synthetase, Trna(leu) and Leucine in The Editing Conformation
40. 4ari: Ternary Complex of E. Coli Leucyl-trna Synthetase, Trna(leu) and The Benzoxaborole An2679 in The Editing Conformation
41. 4as1: Ternary Complex of E. Coli Leucyl-trna Synthetase, Trna(leu) and The Benzoxaborole An2679 in The Editing Conformation
42. 6kid: Crystal Structure of Human Leucyl-trna Synthetase, Atp-bound Form
43. 3zgz: Ternary Complex of E. Coli Leucyl-trna Synthetase, Trna(leu) and Toxic Moiety from Agrocin 84 (tm84) in Aminoacylation- like Conformation
44. 3ziu: Crystal Structure of Mycoplasma Mobile Leucyl-trna Synthetase with Leu-ams in The Active Site
45. 3zjt: Ternary Complex of E .coli Leucyl-trna Synthetase, Trna(leu) 574 The Benzoxaborole An3017 in The Editing Conformation
46. 3zju: Ternary Complex of E .coli Leucyl-trna Synthetase, Trna(leu) and The Benzoxaborole An3016 in The Editing Conformation
47. 3zjv: Ternary Complex of E .coli Leucyl-trna Synthetase, Trna(leu) and The Benzoxaborole An3213 in The Editing Conformation
48. 4cqn: Crystal Structure of The E.coli Leurs-trna Complex with The Non-cognate Isoleucyl Adenylate Analogue
49. 4k47: Structure of The Streptococcus Pneumoniae Leucyl-trna Synthetase Editing Domain Bound to a Benzoxaborole-amp Adduct
50. 4k48: Structure of The Streptococcus Pneumoniae Leucyl-trna Synthetase Editing Domain
51. 5onh: Quaternary Complex of Wild Type E. Coli Leucyl-trna Synthetase with Trna(leu), Leucyl-adenylate Analogue, and Post-transfer Editing Analogue of Norvaline in The Aminoacylation Conformation
52. 5on3: Quaternary Complex of Mutant T252A of E. Coli Leucyl-trna Synthetase with Trna(leu), Leucyl-adenylate Analogue, and Post-transfer Editing Analogue of Leucine in The Aminoacylation Conformation
53. 5on2: Quaternary Complex of Mutant T252A of E. Coli Leucyl-trna Synthetase with Trna(leu), Leucyl-adenylate Analogue, and Post-transfer Editing Analogue of Norvaline in The Aminoacylation Conformation
54. 5omw: Mutant T252A of E. Coli Leucyl-trna Synthetase, Trna(leu) and Leucyl- Adenylate Analogue in The Aminoacylation Conformation
55. 5fon: Crystal Structure of The Cryptosporidium Muris Cytosolic Leucyl-trna Synthetase Editing Domain (apo Structure)
56. 5fom: Crystal Structure of The Cryptosporidium Muris Cytosolic Leucyl-trna Synthetase Editing Domain Complex with The Adduct Amp-an6426
57. 5fol: Crystal Structure of The Cryptosporidium Muris Cytosolic Leucyl-trna Synthetase Editing Domain Complex with a Post- Transfer Editing Analogue of Isoeucine (ILE2AA)
58. 5fog: Crystal Structure of Hte Cryptosporidium Muris Cytosolic Leucyl-trna Synthetase Editing Domain Complex with a Post- Transfer Editing Analogue of Norvaline (NV2AA)
59. 5fof: Crystal Structure of The P.knowlesi Cytosolic Leucyl-trna Synthetase Editing Domain
60. 5fod: Crystal Structure of The P.falciparum Cytosolic Leucyl-trna Synthetase Editing Domain (space Group P1) Containing Deletions of Insertions 1 and 3
61. 5foc: Crystal Structure of The P.falciparum Cytosolic Leucyl-trna Synthetase Editing Domain (space Group P21)
62. 5fo4: Crystal Structure of The P.falciparum Cytosolic Leucyl- Trna Synthetase Editing Domain (space Group P1)
63. 5ah5: Crystal Structure of The Ternary Complex of Agrobacterium Radiobacter K84 Agnb2 Leurs-trna-leuams
64. 5agt: Crystal Structure of The Leurs Editing Domain of Mycobacterium Tuberculosis in Complex with The Adduct (s)-3-(aminomethyl)-4- Chloro-7-ethoxybenzo[c][1,2]oxaborol-1(3h)-ol-amp
65. 5ags: Crystal Structure of The Leurs Editing Domain of Mycobacterium Tuberculosis in Complex with The Adduct 3-(aminomethyl)-4-bromo-7- Ethoxybenzo[c][1,2]oxaborol-1(3h)-ol-amp
66. 5agr: Crystal Structure of The Leurs Editing Domain of Mycobacterium Tuberculosis in Complex with The Adduct (s)-3-(aminomethyl)-7- Ethoxybenzo[c][1,2]oxaborol-1(3h)-ol-amp
67. 5agj: Crystal Structure of The Leurs Editing Domain of Candida Albicans in Complex with The Adduct An2690-amp
68. 5agi: Crystal Structure of The Leurs Editing Domain of Candida Albicans Mutant K510A in Complex with The Adduct Formed by An2690-amp
69. 5agh: Crystal Structure of The Leurs Editing Domain of Candida Albicans Mutant K510A
70. 7n11: Crystal Structure of The M. Abscessus Leurs Editing Domain in Complex with Epetraborole-amp Adduct
71. 7n12: Crystal Structure of The M. Abscessus Leurs Editing Domain in Complex with Epetraborole-amp Adduct