EC 6.5.1.2 - poly(deoxyribonucleotide) :poly(deoxyribonucleotide) ligase (AMP- forming, NMN- forming)

3D structures of EC 6.5.1.2 in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1b04: Structure of The Adenylation Domain of an Nad+ Dependent Ligase
2. 1dgs: Crystal Structure of Nad+-dependent Dna Ligase from T. Filiformis
3. 1l7b: Solution Nmr Structure of Brct Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT
4. 3jsn: Crystal Structure of The Adenylation Domain of Nad+- Dependent Dna Ligase from Staphylococcus Aureus
5. 3jsl: Crystal Structure of The Adenylation Domain of Nad+- Dependent Dna Ligase from Staphylococcus Aureus
6. 1ta8: Structural Rearrangement Accompanying Nad+ Synthesis within a Bacterial Dna Ligase Crystal
7. 1tae: Structural Rearrangement Accompanying Nad+ Synthesis within a Bacterial Dna Ligase Crystal
8. 1v9p: Crystal Structure of Nad+-dependent Dna Ligase
9. 3bac: Structural Basis for The Inhibition of Bacterial Nad+ Dependent Dna Ligase
10. 3bab: Structural Basis for The Inhibition of Bacterial Nad+ Dependent Dna Ligase
11. 3baa: Structural Basis for The Inhibition of Bacterial Nad+ Dependent Dna Ligase
12. 3ba9: Structural Basis for Inhbition of Nad-dependent Ligase
13. 3ba8: Structural Basis for The Inhibition of Bacterial Nad+ Dependent Dna Ligase
14. 1zau: Adenylation Domain of Nad+ Dependent Dna Ligase from M.tuberculosis
15. 7k72: Structure of Dna Ligase a from Mycobacterium Tuberculosis Bound to Nad
16. 2owo: Last Stop on The Road to Repair: Structure of E.coli Dna Ligase Bound to Nicked Dna-adenylate
17. 6ksd: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
18. 6ksc: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
19. 6krh: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
20. 6kkv: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
21. 6kjm: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
22. 6kdu: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
23. 3pn1: Novel Bacterial Nad+-dependent Dna Ligase Inhibitors with Broad Spectrum Potency and Antibacterial Efficacy in Vivo
24. 3uq8: Structure of Adenylation Domain of Haemophilus Influenzae Dna Ligases Bound to Nad+ in Adenylated State.
25. 3sgi: Crystal Structure of Dna Ligase a Brct Domain Deleted Mutant of Mycobacterium Tuberculosis
26. 4glw: Dna Ligase a in Complex with Inhibitor
27. 4glx: Dna Ligase a in Complex with Inhibitor
28. 4eeq: Crystal Structure of E. Faecalis Dna Ligase with Inhibitor
29. 4efb: Crystal Structure of Dna Ligase
30. 4efe: Crystal Structure of Dna Ligase
31. 4cc5: Fragment-based Discovery of 6 Azaindazoles as Inhibitors of Bacterial Dna Ligase
32. 4cc6: Fragment-based Discovery of 6 Azaindazoles as Inhibitors of Bacterial Dna Ligase
33. 4lh6: Crystal Structure of a Liga Inhibitor
34. 4lh7: Crystal Structure of a Liga Inhibitor
35. 5tt5: Escherichia Coli Liga (K115M) in Complex with Nad+
36. 5fpr: Structure of Bacterial Dna Ligase with Small-molecule Ligand Pyrimidin-2-amine (at371) in an Alternate Binding Site.
37. 5fpo: Structure of Bacterial Dna Ligase with Small-molecule Ligand 1h-indazol-7-amine (at4213) in an Alternate Binding Site.
38. 4uco: Fragment Bound to H.influenza Nad Dependent Dna Ligase
39. 4ucr: Fragment Bound to H.influenza Nad Dependent Dna Ligase
40. 4ucs: Fragment Bound to H.influenza Nad Dependent Dna Ligase
41. 4uct: Fragment Bound to H.influenza Nad Dependent Dna Ligase
42. 4ucu: Fragment Bound to H.influenza Nad Dependent Dna Ligase
43. 4ucv: Fragment Bound to H.influenza Nad Dependent Dna Ligase
44. 4ufz: Synthesis of Novel Nad Dependant Dna Ligase Inhibitors via Negishi Cross-coupling: Development of Sar and Resistance Studies
45. 6lw8: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis