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enzyme (lysozyme)

 
Enzymes
  Enzyme classes:
  EC 1: Oxidoreductases
  EC 2: Transferases
  EC 3: Hydrolases
  EC 4: Lyases
  EC 5: Isomerases
  EC 6: Ligases
    EC 6.1
    EC 6.2
    EC 6.3
    EC 6.4
    EC 6.5
      EC 6.5.1
        EC 6.5.1.1
        EC 6.5.1.2
        EC 6.5.1.3
        EC 6.5.1.4
    EC 6.6
  General information:
  Catalytic mechanism
  Enzyme kinetics
  Inhibitors
  Enzymes in industry

EC 6.5.1.2 - poly(deoxyribonucleotide) :poly(deoxyribonucleotide) ligase (AMP- forming, NMN- forming)



3D structures of EC 6.5.1.2 in Protein Data Bank

updated: 6 January 2022, 2:15

In total: 45 PDB structures of EC 6.5.1.2:
  1. 1b04: Structure of The Adenylation Domain of an Nad+ Dependent Ligase
  2. 1dgs: Crystal Structure of Nad+-dependent Dna Ligase from T. Filiformis
  3. 1l7b: Solution Nmr Structure of Brct Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT
  4. 3jsn: Crystal Structure of The Adenylation Domain of Nad+- Dependent Dna Ligase from Staphylococcus Aureus
  5. 3jsl: Crystal Structure of The Adenylation Domain of Nad+- Dependent Dna Ligase from Staphylococcus Aureus
  6. 1ta8: Structural Rearrangement Accompanying Nad+ Synthesis within a Bacterial Dna Ligase Crystal
  7. 1tae: Structural Rearrangement Accompanying Nad+ Synthesis within a Bacterial Dna Ligase Crystal
  8. 1v9p: Crystal Structure of Nad+-dependent Dna Ligase
  9. 3bac: Structural Basis for The Inhibition of Bacterial Nad+ Dependent Dna Ligase
  10. 3bab: Structural Basis for The Inhibition of Bacterial Nad+ Dependent Dna Ligase
  11. 3baa: Structural Basis for The Inhibition of Bacterial Nad+ Dependent Dna Ligase
  12. 3ba9: Structural Basis for Inhbition of Nad-dependent Ligase
  13. 3ba8: Structural Basis for The Inhibition of Bacterial Nad+ Dependent Dna Ligase
  14. 1zau: Adenylation Domain of Nad+ Dependent Dna Ligase from M.tuberculosis
  15. 7k72: Structure of Dna Ligase a from Mycobacterium Tuberculosis Bound to Nad
  16. 2owo: Last Stop on The Road to Repair: Structure of E.coli Dna Ligase Bound to Nicked Dna-adenylate
  17. 6ksd: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
  18. 6ksc: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
  19. 6krh: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
  20. 6kkv: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
  21. 6kjm: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
  22. 6kdu: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
  23. 3pn1: Novel Bacterial Nad+-dependent Dna Ligase Inhibitors with Broad Spectrum Potency and Antibacterial Efficacy in Vivo
  24. 3uq8: Structure of Adenylation Domain of Haemophilus Influenzae Dna Ligases Bound to Nad+ in Adenylated State.
  25. 3sgi: Crystal Structure of Dna Ligase a Brct Domain Deleted Mutant of Mycobacterium Tuberculosis
  26. 4glw: Dna Ligase a in Complex with Inhibitor
  27. 4glx: Dna Ligase a in Complex with Inhibitor
  28. 4eeq: Crystal Structure of E. Faecalis Dna Ligase with Inhibitor
  29. 4efb: Crystal Structure of Dna Ligase
  30. 4efe: Crystal Structure of Dna Ligase
  31. 4cc5: Fragment-based Discovery of 6 Azaindazoles as Inhibitors of Bacterial Dna Ligase
  32. 4cc6: Fragment-based Discovery of 6 Azaindazoles as Inhibitors of Bacterial Dna Ligase
  33. 4lh6: Crystal Structure of a Liga Inhibitor
  34. 4lh7: Crystal Structure of a Liga Inhibitor
  35. 5tt5: Escherichia Coli Liga (K115M) in Complex with Nad+
  36. 5fpr: Structure of Bacterial Dna Ligase with Small-molecule Ligand Pyrimidin-2-amine (at371) in an Alternate Binding Site.
  37. 5fpo: Structure of Bacterial Dna Ligase with Small-molecule Ligand 1h-indazol-7-amine (at4213) in an Alternate Binding Site.
  38. 4uco: Fragment Bound to H.influenza Nad Dependent Dna Ligase
  39. 4ucr: Fragment Bound to H.influenza Nad Dependent Dna Ligase
  40. 4ucs: Fragment Bound to H.influenza Nad Dependent Dna Ligase
  41. 4uct: Fragment Bound to H.influenza Nad Dependent Dna Ligase
  42. 4ucu: Fragment Bound to H.influenza Nad Dependent Dna Ligase
  43. 4ucv: Fragment Bound to H.influenza Nad Dependent Dna Ligase
  44. 4ufz: Synthesis of Novel Nad Dependant Dna Ligase Inhibitors via Negishi Cross-coupling: Development of Sar and Resistance Studies
  45. 6lw8: Structural Basis for Domain Rotation during Adenylation of Active Site K123 and Fragment Library Screening against Nad+ -dependent Dna Ligase from Mycobacterium Tuberculosis
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