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enzyme (lysozyme)

 
Enzymes
  Enzyme classes:
  EC 1: Oxidoreductases
  EC 2: Transferases
    EC 2.1
    EC 2.2
    EC 2.3
    EC 2.4
    EC 2.5
    EC 2.6
    EC 2.7
      EC 2.7.1
      EC 2.7.2
      EC 2.7.3
      EC 2.7.4
        EC 2.7.4.1
        EC 2.7.4.2
        EC 2.7.4.3
        EC 2.7.4.4
        EC 2.7.4.5
        EC 2.7.4.6
        EC 2.7.4.7
        EC 2.7.4.8
        EC 2.7.4.9
        EC 2.7.4.10
        EC 2.7.4.11
        EC 2.7.4.12
        EC 2.7.4.13
        EC 2.7.4.14
        EC 2.7.4.15
        EC 2.7.4.16
        EC 2.7.4.17
        EC 2.7.4.18
        EC 2.7.4.19
        EC 2.7.4.20
        EC 2.7.4.21
        EC 2.7.4.22
        EC 2.7.4.23
        EC 2.7.4.24
      EC 2.7.5
      EC 2.7.6
      EC 2.7.7
      EC 2.7.8
      EC 2.7.9
      EC 2.7.10
      EC 2.7.11
      EC 2.7.12
      EC 2.7.13
      EC 2.7.14
    EC 2.8
    EC 2.9
  EC 3: Hydrolases
  EC 4: Lyases
  EC 5: Isomerases
  EC 6: Ligases
  General information:
  Catalytic mechanism
  Enzyme kinetics
  Inhibitors
  Enzymes in industry

EC 2.7.4.9 - ATP:dTMP phosphotransferase (dTMP kinase)



3D structures of EC 2.7.4.9 - dTMP kinase in Protein Data Bank

updated: 29 May 2015, 1:12

In total: 81 PDB structures of EC 2.7.4.9 - dTMP kinase:
  1. 1e2d: Human Thymidylate Kinase Complexed with Thymidine Monophosphate, Adenosine Diphosphate and a Magnesium-ion
  2. 1e2e: Human Thymidylate Kinase Complexed with Thymidine Monophosphate, Adenosine Diphosphate,a Magnesium-ion and Alf3
  3. 1e2f: Human Thymidylate Kinase Complexed with Thymidine Monophosphate, Adenosine Diphosphate and a Magnesium-ion
  4. 1e2g: Human Thymidylate Kinase Complexed with Adp, Tdp and a Magnesium-ion
  5. 1e2q: Human Thymidylate Kinase Complexed with TP5A and a Magnesium-ion
  6. 1e98: Wild Type Human Thymidylate Kinase Complexed with Aztmp and Adp
  7. 1e99: Human Thymidylate Kinase Complexed with Aztmp and Adp
  8. 1e9a: Human Thymidylate Kinase Complexed with The Bisubstrate Inhibitor AZTP5A
  9. 1e9b: Human Thymidylate Kinase Complexed with Aztmp and Appnp
  10. 1e9c: Mutant Human Thymidylate Kinase Complexed with Tmp and Appnp
  11. 1e9d: Mutant Human Thymidylate Kinase (F105Y) Complexed with Aztmp and Adp
  12. 1e9e: Mutant Human Thymidylate Kinase (F105Y) Complexed with Dtmp and Adp
  13. 1e9f: Mutant Human Thymidylate Kinase Complexed with Tmp and Adp
  14. 1g3u: Crystal Structure of Mycobacterium Tuberculosis Thymidylate Kinase Complexed with Thymidine Monophosphate (tmp)
  15. 1gsi: Crystal Structure of Mycobacterium Tuberculosis Thymidylate Kinase Complexed with Thymidine Monophosphate (tmp)
  16. 1gtv: Crystal Structure of Mycobacterium Tuberculosis Thymidylate Kinase Complexed with Thymidine-5'-diphosphate (tdp)
  17. 5tmp: Complex of E. Coli Thymidylate Kinase with The Bisubstrate Inhibitor AZTP5A
  18. 4tmk: Complex of E. Coli Thymidylate Kinase with The Bisubstrate Inhibitor TP5A
  19. 3tmk: Crystal Structure of Yeast Thymidylate Kinase Complexed with The Bisubstrate Inhibitor TP5A at 2.0 a Resolution: Implications for Catalysis and Azt Activation
  20. 3n2i: 2.25 Angstrom Resolution Crystal Structure of a Thymidylate Kinase (tmk) from Vibrio Cholerae O1 Biovar Eltor Str. N16961 in Complex with Thymidine
  21. 1mrn: Crystal Structure of Mycobacterium Tuberculosis Thymidylate Kinase Complexed with Bisubstrate Inhibitor (TP5A)
  22. 1mrs: Crystal Structure of Mycobacterium Tuberculosis Thymidylate Kinase Complexed with 5-CH2OH Deoxyuridine Monophosphate
  23. 1n5i: Crystal Structure of Inactive Mycobacterium Tuberculosis Thymidylate Kinase Complexed with Thymidine Monophosphate (tmp) at Ph 4.6 (resolution 1.85 A)
  24. 1n5j: Crystal Structure of Mycobacterium Tuberculosis Thymidylate Kinase Complexed with Thymidine Diphosphate (tdp) and Thymidine Triphosphate (ttp) at Ph 5.4 (1.85 a Resolution)
  25. 1n5k: Crystal Structure of Mycobacterium Tuberculosis Thymidylate Kinase Crystallized in Sodium Malonate (resolution 2.1 A)
  26. 1n5l: Crystal Structure of Mycobacterium Tuberculosis Thymidylate Kinase Crystallized in Sodium Malonate, after Catalysis in The Crystal (2.3 a Resolution)
  27. 3lv8: 1.8 Angstrom Resolution Crystal Structure of a Thymidylate Kinase (tmk) from Vibrio Cholerae O1 Biovar Eltor Str. N16961 in Complex with Tmp, Thymidine-5'-diphosphate and Adp
  28. 3ld9: Crystal Structure of Thymidylate Kinase from Ehrlichia Chaffeensis at 2.15a Resolution
  29. 1nmx: Crystal Structure of Human Thymidylate Kinase with Fltmp and Adp
  30. 1nmy: Crystal Structure of Human Thymidylate Kinase with Fltmp and Appnhp
  31. 1nmz: Crystal Structure of Human Thymidylate Kinase with NH2TMP and Appnhp
  32. 1nn0: Crystal Structure of Human Thymidylate Kinase with Ddtmp and Adp
  33. 1nn1: Crystal Structure of Human Thymidylate Kinase with Ddtmp and Appnhp
  34. 1nn3: Crystal Structure of Human Thymidylate Kinase with D4TMP + Adp
  35. 1nn5: Crystal Structure of Human Thymidylate Kinase with D4TMP + Appnhp
  36. 3hjn: Crystal Structure of Thymidylate Kinase in Complex with Dtdp and Adp from Thermotoga Maritima
  37. 1tmk: Yeast Thymidylate Kinase Complexed with Thymidine Monophosphate (dtmp)
  38. 1w2g: Crystal Structure of Mycobacterium Tuberculosis Thymidylate Kinase Complexed with Deoxythymidine (dt) (2.1 a Resolution)
  39. 1w2h: Crystal Structure of Mycobacterium Tuberculosis Thymidylate Kinase Complexed with Azidothymidine Monophosphate (azt-mp) (2.0 a Resolution)
  40. 2wwi: Plasmodium Falciparum Thymidylate Kinase in Complex with Aztmp and Adp
  41. 2wwh: Plasmodium Falciparum Thymidylate Kinase in Complex with AP5DT
  42. 2wwg: Plasmodium Falciparum Thymidylate Kinase in Complex with Dgmp and Adp
  43. 2wwf: Plasmodium Falciparum Thymidylate Kinase in Complex with Tmp and Adp
  44. 2w0s: Crystal Structure of Vaccinia Virus Thymidylate Kinase Bound to Brivudin-5'-monophosphate
  45. 2v54: Crystal Structure of Vaccinia Virus Thymidylate Kinase Bound to Tdp
  46. 2tmk: Yeast Thymidylate Kinase Complexed with 3'-azido-3'- Deoxythymidine Monophosphate (azt-mp)
  47. 2ccg: Crystal Structure of His-tagged S. Aureus Thymidylate Kinase Complexed with Thymidine Monophosphate (tmp)
  48. 2ccj: Crystal Structure of S. Aureus Thymidylate Kinase Complexed with Thymidine Monophosphate
  49. 2cck: Crystal Structure of Unliganded S. Aureus Thymidylate Kinase
  50. 2plr: Crystal Structure of Dtmp Kinase (st1543) from Sulfolobus Tokodaii Strain7
  51. 2pbr: Crystal Structure of Thymidylate Kinase (aq_969) from Aquifex Aeolicus Vf5
  52. 2xx3: Human Thymidylate Kinase Complexed with Thymidine Butenyl Phosphonate Monophosphate and Adp
  53. 3v9p: Crystal Structure of Thymidylate Kinase from Burkholderia Thailandensis
  54. 3uwk: Structure Guided Development of Novel Thymidine Mimetics Targeting Pseudomonas Aeruginosa Thymidylate Kinase: from Hit to Lead Generation
  55. 3uwo: Structure Guided Development of Novel Thymidine Mimetics Targeting Pseudomonas Aeruginosa Thymidylate Kinase: from Hit to Lead Generation
  56. 3uxm: Structure Guided Development of Novel Thymidine Mimetics Targeting Pseudomonas Aeruginosa Thymidylate Kinase: from Hit to Lead Generation
  57. 4dwj: Crystal Structure of Thymidylate Kinase from Staphylococcus Aureus in Complex with Thymidine Monophosphate
  58. 4e5u: The Crystal Structure of Thymidylate Kinase from Pseudomonas Aeruginosa Pao1 in Complex with Thymidine Monophosphate.
  59. 4eaq: Crystal Structure of Thymidylate Kinase from Staphylococcus Aureus in Complex with 3'-azido-3'-deoxythymidine-5'-monophosphate
  60. 4edh: The Crystal Structure of Thymidylate Kinase from Pseudomonas Aeruginosa Pao1 in Complex with Adp,tmp and Mg.
  61. 4esh: The Crystal Structure of Thymidylate Kinase from Pseudomonas Aeruginosa Pao1 in Complex with Deoxythymidine.
  62. 4f4i: Crystal Structure of Thymidylate Kinase from Staphylococcus Aureus in Apo-form
  63. 4gmd: The Crystal Structure of Thymidylate Kinase from Pseudomonas Aeruginosa Pao1 in Complex with Azt Monophosphate
  64. 4gfd: Thymidylate Kinase (tmk) from S. Aureus in Complex with Tk-666
  65. 4gsy: Crystal Structure of Thymidylate Kinase from Staphylococcus Aureus Bound to Inhibitor.
  66. 4hdc: Discovery of Selective and Potent Inhibitors of Gram-positive Bacterial Thymidylate Kinase (tmk: Compound 41)
  67. 4hej: Discovery of Selective and Potent Inhibitors of Gram-positive Bacterial Thymidylate Kinase (tmk): Compund 16
  68. 4hlc: Sulfonylpiperidines as Novel, Antibacterial Inhibitors of Gram- Positive Thymidylate Kinase (tmk): Compound 5
  69. 4hld: Sulfonylpiperidines as Novel, Antibacterial Inhibitors of Gram- Positive Thymidylate Kinase (tmk): Compound 11
  70. 2yof: Plasmodium Falciparum Thymidylate Kinase in Complex with a (thio)urea-beta-deoxythymidine Inhibitor
  71. 2yog: Plasmodium Falciparum Thymidylate Kinase in Complex with a (thio)urea-alpha-deoxythymidine Inhibitor
  72. 2yoh: Plasmodium Falciparum Thymidylate Kinase in Complex with a Urea-alpha-deoxythymidine Inhibitor
  73. 4mqb: Crystal Structure of Thymidylate Kinase from Staphylococcus Aureus in Complex with 2-(n-morpholino)ethanesulfonic Acid
  74. 4qg7: S.aureus Tmk in Complex with a Potent Inhibitor Compound 18, 2-(3- Chlorophenoxy)-3-methoxy-4-{[(3s)-3-(5-methyl-2,4-dioxo-3,4- Dihydropyrimidin-1(2h)-yl)piperidin-1-yl]methyl}benzoic Acid
  75. 4qga: S.aureus Tmk in Complex with Potent Inhibitor Compound 19, 2-(3- Chlorophenoxy)-3-fluoro-4-{[(3s)-3-(5-methyl-2,4-dioxo-3,4- Dihydropyrimidin-1(2h)-yl)piperidin-1-yl]methyl}benzoic Acid
  76. 4qgf: S.aureus Tmk in Complex with The Potent Inhibitor Compound 38, 2-(3- Chlorophenoxy)-3-methoxy-4-{(1r)-1-[(3s)-3-(5-methyl-2,4-dioxo-3,4- Dihydropyrimidin-1(2h)-yl)piperidin-1-yl]propyl}benzoic Acid
  77. 4qgg: Tmk in Complex with Compound 46, 2-(3-chlorophenoxy)-3-fluoro-4-{(1r)- 3-methyl-1-[(3s)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)- Yl)piperidin-1-yl]butyl}benzoic Acid
  78. 4qgh: S.aureus Tmk in Complex with Potent Inhibitor Compound 47
  79. 4nzy: Crystal Structure (type-2) of Dtmp Kinase (st1543) from Sulfolobus Tokodaii Strain7
  80. 4unp: Mtb Tmk in Complex with Compound 34
  81. 4xwa: Tmk from S.aureus in Complex with The Piperidinyl Thymine Class Inhibitor with a C5 Ethyl-amine
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