EC 3.4.22.38 - cathepsin K

3D structures of EC 3.4.22.38 - cathepsin K in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1atk: Crystal Structure of The Cysteine Protease Human Cathepsin K in Complex with The Covalent Inhibitor E-64
2. 1au0: Crystal Structure of The Cysteine Protease Human Cathepsin K in Complex with a Covalent Symmetric Diacylaminomethyl Ketone Inhibitor
3. 1au2: Crystal Structure of The Cysteine Protease Human Cathepsin K in Complex with a Covalent Propanone Inhibitor
4. 1au3: Crystal Structure of The Cysteine Protease Human Cathepsin K in Complex with a Covalent Pyrrolidinone Inhibitor
5. 1au4: Crystal Structure of The Cysteine Protease Human Cathepsin K in Complex with a Covalent Pyrrolidinone Inhibitor
6. 1ayu: Crystal Structure of Cysteine Protease Human Cathepsin K in Complex with a Covalent Symmetric Biscarbohydrazide Inhibitor
7. 1ayv: Crystal Structure of Cysteine Protease Human Cathepsin K in Complex with a Covalent Thiazolhydrazide Inhibitor
8. 1ayw: Crystal Structure of Cysteine Protease Human Cathepsin K in Complex with a Covalent Benzyloxybenzoylcarbohydrazide Inhibitor
9. 1bgo: Crystal Structure of Cysteine Protease Human Cathepsin K in Complex with a Covalent Peptidomimetic Inhibitor
10. 1by8: The Crystal Structure of Human Procathepsin K
11. 7pck: Crystal Structure of Wild Type Human Procathepsin K
12. 3o1g: Cathepsin K Covalently Bound to a 2-cyano Pyrimidine Inhibitor with a Benzyl P3 Group.
13. 1mem: Crystal Structure of Cathepsin K Complexed with a Potent Vinyl Sulfone Inhibitor
14. 1nl6: Crystal Structure of The Cysteine Protease Human Cathepsin K in Complex with a Covalent Azepanone Inhibitor
15. 1nlj: Crystal Structure of The Cysteine Protease Human Cathepsin K in Complex with a Covalent Azepanone Inhibitor
16. 6ql8: Cathepsin-k in Complex with Miv-711
17. 3kx1: Cathepsin K in Complex with a Selective 2-cyano-pyrimidine Inhibitor
18. 3kwz: Cathepsin K in Complex with a Non-selective 2-cyano- Pyrimidine Inhibitor
19. 3kwb: Structure of Catk Covalently Bound to a Dioxo-triazine Inhibitor
20. 3kw9: X-ray Structure of Cathepsin K Covalently Bound to a Triazine Ligand
21. 1q6k: Cathepsin K Complexed with T-butyl(1s)-1-cyclohexyl-2- Oxoethylcarbamate
22. 3h7d: The Crystal Structure of The Cathepsin K Variant M5 in Complex with Chondroitin-4-sulfate
23. 1snk: Cathepsin K Complexed with Carbamate Derivatized Norleucine Aldehyde
24. 6qlm: Cathepsin-k in Complex with Miv-701
25. 1tu6: Cathepsin K Complexed with a Ketoamide Inhibitor
26. 1u9v: Crystal Structure of The Cysteine Protease Human Cathepsin K in Complex with The Covalent Inhibitor Nvp-abe854
27. 1u9w: Crystal Structure of The Cysteine Protease Human Cathepsin K in Complex with The Covalent Inhibitor Nvp-abi491
28. 1u9x: Crystal Structure of The Cysteine Protease Human Cathepsin K in Complex with The Covalent Inhibitor Nvp-abj688
29. 3c9e: Crystal Structure of The Cathepsin K : Chondroitin Sulfate Complex.
30. 1vsn: Crystal Structure of a Potent Small Molecule Inhibitor Bound to Cathepsin K
31. 6qlw: Cathepsin-k in Complex with Miv-710
32. 6qlx: Cathepsin-k in Complex with Fluoro-oxa-azabicyclo[3.3.0]octanyl Containing Inhibitor
33. 1yk7: Cathepsin K Complexed with a Cyanopyrrolidine Inhibitor
34. 1yk8: Cathepsin K Complexed with a Cyanamide-based Inhibitor
35. 1yt7: Cathepsin K Complexed with a Constrained Ketoamide Inhibitor
36. 2ato: Crystal Structure of Human Cathepsin K in Complex with Myocrisin
37. 2aux: Cathepsin K Complexed with a Semicarbazone Inhibitor
38. 2auz: Cathepsin K Complexed with a Semicarbazone Inhibitor
39. 2bdl: Cathepsin K Complexed with a Pyrrolidine Ketoamide-based Inhibitor
40. 2r6n: Crystal Structure of a Pyrrolopyrimidine Inhibitor in Complex with Human Cathepsin K
41. 6bki: Crystal Structure of T101A Variant Mouse Cathepsin K at 2.94 Angstrom Resolution.
42. 6ash: Crystal Structure of Human Cathepsin K with a Non-active Site Inhibitor at 1.42 Angstrom Resolution
43. 2f7d: A Mutant Rabbit Cathepsin K with a Nitrile Inhibitor
44. 2ftd: Crystal Structure of Cathepsin K Complexed with 7-methyl- Substituted Azepan-3-one Compound
45. 5z5o: Structure of Pycnonodysostosis Disease Related I249T Mutant of Human Cathepsin K
46. 6pxf: Structure of Human Cathepsin K with an Ectosteric Inhibitor at 1.85 Angstrom Resolution
47. 3ovz: Cathepsin K in Complex with a Covalent Inhibitor with a Ketoamide Warhead
48. 3o0u: Cathepsin K Covalently Bound to a Cyano-pyrimidine Inhibitor with Improved Selectivity over Herg
49. 6qbs: The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K
50. 4dmx: Cathepsin K Inhibitor
51. 4dmy: Cathepsin K Inhibitor
52. 6qm0: Cathepsin-k in Complex with Amino-oxaazabicyclo[3.3.0]octanyl Containing Inhibitor
53. 6hgy: Crystal Structure of Cathepsin K with N-desmethyl Thalassospiramide C
54. 4n79: Structure of Cathepsin K-dermatan Sulfate Complex
55. 4n8w: Cathepsin K - Chondroitin Sulfate Complex
56. 5tun: Crystal Structure of Uninhibited Human Cathepsin K at 1.62 Angstrom Resolution
57. 5tdi: Crystal Structure of Cathepsin K with a Covalently-linked Inhibitor at 1.4 Angstrom Resolution.
58. 5t6u: Crystal Structure of Mouse Cathepsin K at 2.9 Angstroms Resolution.
59. 5jh3: Human Cathepsin K Mutant C25S
60. 5ja7: Human Cathepsin K Mutant C25S in Complex with The Allosteric Effector Nsc94914
61. 5j94: Human Cathepsin K Mutant C25S in Complex with The Allosteric Effector Nsc13345
62. 4yva: Cathepsin K Co-crystallized with Actinomycetes Extract
63. 4yv8: Crystal Structure of Cathepsin K Bound to The Covalent Inhibitor Lichostatinal
64. 4x6h: Development of N-(functionalized Benzoyl)-homocycloleucyl- Glycinonitriles as Potent Cathepsin K Inhibitors.
65. 4x6i: Development of N-(functionalized Benzoyl)-homocycloleucyl- Glycinonitriles as Potent Cathepsin K Inhibitors.
66. 4x6j: Development of N-(functionalized Benzoyl)-homocycloleucyl- Glycinonitriles as Potent Cathepsin K Inhibitors.
67. 7nxm: Structure of Human Cathepsin K in Complex with The Selective Activity- Based Probe Gu3416