EC 2.4.2.30 - NAD ⁺ :poly(adenosine- diphosphate- D- ribosyl) - acceptor ADP- D- ribosyl- transferase (NAD ⁺ ADP- ribosyltransferase)

3D structures of EC 2.4.2.30 - NAD+ ADP-ribosyltransferase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1a26: The Catalytic Fragment of Poly(adp-ribose) Polymerase Complexed with Carba-nad
2. 1efy: Crystal Structure of The Catalytic Fragment of Poly (adp- Ribose) Polymerase Complexed with a Benzimidazole Inhibitor
3. 1gs0: Crystal Structure of The Catalytic Fragment of Murine Poly (adp-ribose) Polymerase-2
4. 4pax: The Catalytic Fragment of Poly(adp-ribose) Polymerase Complexed with 8-hydroxy-2-methyl-3-hydro-quinazolin-4-one
5. 3pax: The Catalytic Fragment of Poly(adp-ribose) Polymerase Complexed with 3-methoxybenzamide
6. 3p0q: Human Tankyrase 2 - Catalytic Parp Domain in Complex with an Inhibitor
7. 3p0p: Human Tankyrase 2 - Catalytic Parp Domain in Complex with an Inhibitor
8. 3p0n: Human Tankyrase 2 - Catalytic Parp Domain in Complex with an Inhibitor
9. 6ntu: Crystal Structure of Human Parp-1 Art Domain Bound to Inhibitor Uktt- 15
10. 3mhk: Human Tankyrase 2 - Catalytic Parp Domain in Complex with 2-(2- Pyridyl)-7,8-dihydro-5h-thiino[4,3-d]pyrimidin-4-ol
11. 3mhj: Human Tankyrase 2 - Catalytic Parp Domain in Complex with 1-methyl-3- (trifluoromethyl)-5h-benzo[c][1,8]naphtyridine-6-one
12. 3l3m: Parp Complexed with A927929
13. 3kr8: Human Tankyrase 2 - Catalytic Parp Domain in Complex with an Inhibitor Xav939
14. 3kr7: Human Tankyrase 2 - Catalytic Parp Domain
15. 3kjd: Human Poly(adp-ribose) Polymerase 2, Catalytic Fragment in Complex with an Inhibitor Abt-888
16. 3kcz: Human Poly(adp-ribose) Polymerase 2, Catalytic Fragment in Complex with an Inhibitor 3-aminobenzamide
17. 1pax: The Catalytic Fragment of Poly(adp-ribose) Polymerase Complexed with 3,4-dihydro-5-methyl-isoquinolinone
18. 3hkv: Human Poly(adp-ribose) Polymerase 10, Catalytic Fragment in Complex with an Inhibitor 3-aminobenzamide
19. 1qs1: Crystal Structure of Vegetative Insecticidal Protein2 (vip2)
20. 1qs2: Crystal Structure of Vip2 with Nad
21. 3goy: Crystal Structure of Human Poly(adp-ribose) Polymerase 14, Catalytic Fragment in Complex with an Inhibitor 3- Aminobenzamide
22. 3gn7: Parp Complexed with A861696
23. 3gjw: Parp Complexed with A968427
24. 3gey: Crystal Structure of Human Poly(adp-ribose) Polymerase 15, Catalytic Fragment in Complex with an Inhibitor Pj34
25. 3fhb: Human Poly(adp-ribose) Polymerase 3, Catalytic Fragment in Complex with an Inhibitor 3-aminobenzoic Acid
26. 1uk0: Crystal Structure of Catalytic Domain of Human Poly(adp- Ribose) Polymerase with a Novel Inhibitor
27. 1uk1: Crystal Structure of Human Poly(adp-ribose) Polymerase Complexed with a Potent Inhibitor
28. 1uzi: C3 Exoenzyme from Clostridium Botulinum, Tetragonal Form
29. 3ce0: Human Poly(adp-ribose) Polymerase 3, Catalytic Fragment in Complex with an Inhibitor Pj34
30. 1v9x: Solution Structure of The First Zn-finger Domain of Poly(adp-ribose) Polymerase-1
31. 3c4h: Human Poly(adp-ribose) Polymerase 3, Catalytic Fragment in Complex with an Inhibitor Dr2313
32. 3c49: Human Poly(adp-ribose) Polymerase 3, Catalytic Fragment in Complex with an Inhibitor Ku0058948
33. 3blj: Crystal Structure of Human Poly(adp-ribose) Polymerase 15, Catalytic Fragment
34. 1wok: Crystal Structure of Catalytic Domain of Human Poly(adp- Ribose) Polymerase Complexed with a Quinoxaline-type Inhibitor
35. 7cmw: Complex Structure of Parp1 Catalytic Domain with Pamiparib
36. 6tx3: Hpf1 Bound to Catalytic Fragment of Parp2
37. 2riq: Crystal Structure of The Third Zinc-binding Domain of Human Parp-1
38. 2rf5: Crystal Structure of Human Tankyrase 1- Catalytic Parp Domain
39. 2rd6: Parp Complexed with A861695
40. 2rcw: Parp Complexed with A620223
41. 2cok: Solution Structure of Brct Domain of Poly(adp-ribose) Polymerase-1
42. 2cr9: Solution Structure of Wgr Domain of Poly(adp-ribose) Polymerase-1
43. 2cs2: Solution Structure of The Second Zn-finger Domain of Poly(adp-ribose) Polymerase-1
44. 2pqf: Human Poly(adp-ribose) Polymerase 12, Catalytic Fragment in Complex with an Inhibitor 3-aminobenzoic Acid
45. 2pax: The Catalytic Fragment of Poly(adp-ribose) Polymerase Complexed with 4-amino-1,8-naphthalimide
46. 2paw: The Catalytic Fragment of Poly(adp-ribose) Polymerase
47. 2dmj: Solution Structure of The First Zf-parp Domain of Human Poly(adp-ribose)polymerase-1
48. 6bhv: Human Parp-1 Bound to Nad+ Analog Benzamide Adenine Dinucleotide (bad)
49. 6a84: Tankyrase-2 in Complex with Compound 15d
50. 5zqr: Tankyrase-2 in Complex with Compound 40c
51. 5zqq: Tankyrase-2 in Complex with Compound 52
52. 5zqp: Tankyrase-2 in Complex with Compound 12
53. 5zqo: Tankyrase-2 in Complex with Compound 1a
54. 2eoc: Solution Structure of The Wgr Domain from Human Poly [adp- Ribose] Polymerase-3
55. 2hw2: Crystal Structure of Rifampin Adp-ribosyl Transferase in Complex with Rifampin
56. 6x0n: Bridging of Double-strand Dna Break Activates Parp2/hpf1 to Modify Chromatin
57. 6x0m: Bridging of Double-strand Dna Break Activates Parp2/hpf1 to Modify Chromatin
58. 6x0l: Bridging of Double-strand Dna Break Activates Parp2/hpf1 to Modify Chromatin
59. 2jvn: Domain C of Human Parp-1
60. 6usj: Structure of Two Nucleosomes Bridged by Human Parp2
61. 6urq: Complex Structure of Human Poly-adp-ribosyltransferase Tnks1 Arc2-arc3 and P Antigen Family Member 4 (page4)
62. 2l30: Human Parp-1 Zinc Finger 1
63. 2l31: Human Parp-1 Zinc Finger 2
64. 2y0i: Factor Inhibiting Hif-1 Alpha in Complex with Tankyrase-2 (tnks2) Fragment Peptide (21-mer)
65. 6vkq: Crystal Structure of Human Parp-1 Cat Domain Bound to Inhibitor Eb-47
66. 6vko: Crystal Structure of Human Parp-1 Cat Domain Bound to Inhibitor Uktt15
67. 6vkk: Crystal Structure of Human Parp-1 Cat Domain Bound to Inhibitor Rucaparib
68. 3l3l: Parp Complexed with A906894
69. 3od8: Human Parp-1 Zinc Finger 1 (zn1) Bound to Dna
70. 3oda: Human Parp-1 Zinc Finger 1 (zn1) Bound to Dna
71. 3odc: Human Parp-1 Zinc Finger 2 (zn2) Bound to Dna
72. 3ode: Human Parp-1 Zinc Finger 2 (zn2) Bound to Dna
73. 6xvw: Catalytic Domain of Human Parp-1 in Complex with The Inhibitor Mc2050
74. 3q6z: Human Parp14 (artd8)-macro Domain 1 in Complex with Adenosine-5- Diphosphoribose
75. 3q71: Human Parp14 (artd8) - Macro Domain 2 in Complex with Adenosine-5- Diphosphoribose
76. 6kro: Tankyrase-2 in Complex with Rk-582
77. 3se2: Human Poly(adp-ribose) Polymerase 14 (parp14/artd8) - Catalytic Domain in Complex with 6(5h)-phenanthridinone
78. 3smi: Human Poly(adp-ribose) Polymerase 14 (parp14/artd8) - Catalytic Domain in Complex with a Quinazoline Inhibitor
79. 3smj: Human Poly(adp-ribose) Polymerase 14 (parp14/artd8) - Catalytic Domain in Complex with a Pyrimidine-like Inhibitor
80. 2le0: Parp Brct Domain
81. 3u9h: Complex Structure of Human Tankyrase 2 with Nicotinamide
82. 3twq: Crystal Structure of Arc4 from Human Tankyrase 2 (apo Form)
83. 3twr: Crystal Structure of Arc4 from Human Tankyrase 2 in Complex with Peptide from Human 3bp2
84. 3tws: Crystal Structure of Arc4 from Human Tankyrase 2 in Complex with Peptide from Human Terf1 (chimeric Peptide)
85. 3twt: Crystal Structure of Arc4 from Human Tankyrase 2 in Complex with Peptide from Human Mcl1 (chimeric Peptide)
86. 3twu: Crystal Structure of Arc4 from Human Tankyrase 2 in Complex with Peptide from Human Mcl1
87. 3twv: Crystal Structure of Arc4 from Human Tankyrase 2 in Complex with Peptide from Human Numa1 (chimeric Peptide)
88. 3tww: Crystal Structure of Arc4 from Human Tankyrase 2 in Complex with Peptide from Human Lnpep (chimeric Peptide)
89. 3twx: Crystal Structure of Arc4 from Human Tankyrase 2 in Complex with Peptide from Human Fnbp1 (chimeric Peptide)
90. 6qxu: Human Tnks1 in Complex with 6,8-difluoro-2-[4-(1-hydroxy-1-methyl- Ethyl)-phenyl]-3h-quinazolin-4-one
91. 3v2b: Human Poly(adp-ribose) Polymerase 15 (artd7, Bal3), Macro Domain 2 in Complex with Adenosine-5-diphosphoribose
92. 3utm: Crystal Structure of a Mouse Tankyrase-axin Complex
93. 3u9y: Crystal Structure of Human Tankyrase 2 Catalytic Domain in Complex with Olaparib
94. 3ua9: Crystal Structure of Human Tankyrase 2 in Complex with a Selective Inhibitor
95. 3udd: Tankyrase-1 in Complex with Small Molecule Inhibitor
96. 3uh2: Tankyrase-1 in Complexed with Pj34
97. 3uh4: Tankyrase-1 Complexed with Nvp-xav939
98. 4dvi: Crystal Structure of Tankyrase 1 with Iwr2
99. 6nrj: Crystal Structure of Human Parp-1 Art Domain Bound to Inhibitor Utt93
100. 6nri: Crystal Structure of Human Parp-1 Art Domain Bound to Inhibitor Utt83
101. 6nrh: Crystal Structure of Human Parp-1 Art Domain Bound Inhibitor Utt63
102. 6nrg: Crystal Structure of Human Parp-1 Art Domain Bound to Inhibitor Utt57
103. 6nrf: Crystal Structure of Human Parp-1 Art Domain Bound to Inhibitor Utt103
104. 4dqy: Structure of Human Parp-1 Bound to a Dna Double Strand Break
105. 4av1: Crystal Structure of The Human Parp-1 Dna Binding Domain in Complex with Dna
106. 4avu: Crystal Structure of Human Tankyrase 2 in Complex with 6(5h) -phenanthridinone
107. 4avw: Crystal Structure of Human Tankyrase 2 in Complex with Tiq-a
108. 4f0d: Human Artd15/parp16 in Complex with 3-aminobenzamide
109. 4f0e: Human Adp-ribosyltransferase 7 (artd7/parp15), Catalytic Domain in Complex with Sto1102
110. 4f1l: Human Artd8 (parp14, Bal2) - Catalytic Domain in Complex with Inhibitor A16(z)
111. 4f1q: Human Artd8 (parp14, Bal2) - Catalytic Domain in Complex with A16(e)
112. 6i8t: The Catalytic Fragment of Poly(adp-ribose) Polymerase Complexed with an Isoindolinone Inhibitor
113. 6i8m: The Catalytic Fragment of Poly(adp-ribose) Polymerase Complexed with Isoindolinone Inhibitor
114. 4hki: Tankyrase 2 in Complex with Flavone
115. 4hkk: Complex Structure of Human Tankyrase 2 with Apigenin
116. 4hkn: Complex Structure of Human Tankyrase 2 with Luteolin
117. 4hl5: Complex Structure of Human Tankyrase 2 with 7-hydroxy -4'- Methoxyflavone
118. 4hlf: Crystal Structure of Tankyrase 2 in Complex with 7,3',4'- Trihydroxyflavone
119. 4hlg: Crystal Structure of Tankyrase 2 in Complex with 3'-hydroxyflavone
120. 4hlh: Crystal Structure of Tankyrase 2 in Complex with 4'-fluoroflavone
121. 4hlk: Crystal Structure of Tankyrase 2 in Complex with 4'-methylflavone
122. 4hlm: Crystal Structure of Tankyrase 2 in Complex with 3',4'- Dihydroxyflavone
123. 4hmh: Crystal Structure of Tankyrase 2 in Complex with 7,3-dihydroxyflavone
124. 6hxs: Human Parp16 (artd15) in Complex with Carba-nad
125. 6hxr: Human Parp16 (artd15) in Complex with Eb-47
126. 4abk: Human Parp14 (artd8, Bal2) - Macro Domain 3 in Complex with Adenosine-5-diphosphoribose
127. 4abl: Human Parp14 (artd8, Bal2) - Macro Domain 3
128. 4i9i: Crystal Structure of Tankyrase 1 with Compound 4
129. 3vfq: Human Parp14 (artd8, Bal2) - Macro Domains 1 and 2 in Complex with Adenosine-5-diphosphoribose
130. 4d86: Human Parp14 (artd8, Bal2) - Macro Domains 1 and 2 in Complex with Adenosine-5-diphosphate
131. 4hhy: Crystal Structure of Parp Catalytic Domain in Complex with Novel Inhibitors
132. 4hhz: Crystal Structure of Parp Catalytic Domain in Complex with Novel Inhibitors
133. 4hyf: Structural Basis and Sar for Od 270, a Lead Stage 1,2,4-triazole Based Specific Tankyrase1/2 Inhibitor
134. 6ghk: Human Parp1 (artd1) - Catalytic Domain in Complex with Inhibitor Me0527
135. 6g0w: Human Parp14 (artd8), Catalytic Fragment in Complex with Inhibitor Mcd72
136. 6fzm: Human Parp14 (artd8), Catalytic Fragment in Complex with Inhibitor Itk6
137. 6fym: Human Parp14 (artd8), Catalytic Fragment in Complex with Inhibitor Itk1
138. 6fxi: Human Parp10 (artd10), Catalytic Fragment in Complex with 3- Aminobenzamide and Citrate
139. 4k4e: Co-crystal Structure of Tnks1 with Compound 52 [n~2-(5-chloro-2- Methoxyphenyl)-n-[trans-4-(2-oxo-2,3-dihydro-1h-benzimidazol-1-yl) Cyclohexyl]glycinamide]
140. 4k4f: Co-crystal Structure of Tnks1 with Compound 18 [4-[(4s)-5,5-dimethyl- 2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-n-(quinolin-8-yl)benzamide]
141. 4bfp: Crystal Structure of Human Tankyrase 2 in Complex with Wiki4
142. 4gv0: Human Artd3 (parp3) - Catalytic Domain in Complex with Inhibitor Me0355
143. 4gv2: Human Artd3 (parp3) - Catalytic Domain in Complex with Inhibitor Me0354
144. 4gv4: Human Artd3 (parp3) - Catalytic Domain in Complex with Inhibitor Me0328
145. 4gv7: Human Artd1 (parp1) - Catalytic Domain in Complex with Inhibitor Me0328
146. 4iue: Tankyrase in Complex with 7-(2-fluorophenyl)-4-methyl-1,2- Dihydroquinolin-2-one
147. 4j21: Tankyrase 2 in Complex with 7-(4-amino-2-chlorophenyl)-4- Methylquinolin-2(1h)-one
148. 4j22: Tankyrase 2 in Complex with 3-chloro-4-(4-methyl-2-oxo-1,2- Dihydroquinolin-7-yl)-n-[2-(morpholin-4-yl)ethyl]benzamide
149. 4j3l: Tankyrase 2 in Complex with 3-chloro-n-(2-methoxyethyl)-4-(4-methyl-2- Oxo-1,2-dihydroquinolin-7-yl)benzamide
150. 4j3m: Tankyrase 2 in Complex with 3-chloro-4-(4-methyl-2-oxo-1,2- Dihydroquinolin-7-yl)benzoic Acid
151. 6f5f: Structure of Artd2/parp2 Wgr Domain Bound to Double Strand Dna with 5 Nucleotide Overhang and 5'phosphate
152. 6f5b: Structure of Artd2/parp2 Wgr Domain Bound to Double Stranded Dna with 5'phosphate
153. 3w51: Tankyrase in Complex with 2-hydroxy-4-methylquinoline
154. 6f1k: Structure of Artd2/parp2 Wgr Domain Bound to Double Strand Dna without 5'phosphate
155. 4j1z: Tankyrase 2 in Complex with 4-chloro-1,2-dihydrophatalzin-one
156. 6ek3: Parp15 Catalytic Domain Mutant (Y598L) in Complex with Oul35
157. 4l6s: Parp Complexed with Benzo[1,4]oxazin-3-one Inhibitor
158. 6cf6: Rnf146 Tbm-tankyrase Arc2-3 Complex
159. 4bj9: Crystal Structure of Human Tankyrase 2 in Complex with Eb-47
160. 4bjb: Crystal Structure of Human Tankyrase 2 in Complex with Pj-34
161. 4bjc: Crystal Structure of Human Tankyrase 2 in Complex with Rucaparib
162. 4bs4: Crystal Structure of Human Tankyrase 2 in Complex with 4'-isopropylflavone
163. 4bu3: Crystal Structure of Human Tankyrase 2 in Complex with 2-phenyl-3,4-dihydroquinazolin-4-one
164. 4bu5: Crystal Structure of Human Tankyrase 2 in Complex with 2-(4- Hydroxyphenyl)-3,4-dihydroquinazolin-4-one
165. 4bu6: Crystal Structure of Human Tankyrase 2 in Complex with 2-(4- Aminophenyl)-3,4-dihydroquinazolin-4-one
166. 4bu7: Crystal Structure of Human Tankyrase 2 in Complex with 2-(4- Bromophenyl)-3,4-dihydroquinazolin-4-one
167. 4bu8: Crystal Structure of Human Tankyrase 2 in Complex with 4-(4- Oxo-1,4-dihydroquinazolin-2-yl)benzonitrile
168. 4bu9: Crystal Structure of Human Tankyrase 2 in Complex with 2-(4- Methoxyphenyl)-3,4-dihydroquinazolin-4-one
169. 4bua: Crystal Structure of Human Tankyrase 2 in Complex with 2-(4- (methylsulfanyl)phenyl)-3,4-dihydroquinazolin-4-one
170. 4bud: Crystal Structure of Human Tankyrase 2 in Complex with 2-(4- Tert-butylphenyl)-1,4-dihydroquinazolin-4-one
171. 4bue: Crystal Structure of Human Tankyrase 2 in Complex with 3-methyl- N-(4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl)butanamide
172. 4buf: Crystal Structure of Human Tankyrase 2 in Complex with 2-(4- Acetylphenyl)-3,4-dihydroquinazolin-4-one
173. 4bui: Crystal Structure of Human Tankyrase 2 in Complex with Methyl 4-(4-oxo-3,4-dihydroquinazolin-2-yl)benzoate
174. 4bus: Crystal Structure of Human Tankyrase 2 in Complex with 2-(4- (4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetic Acid
175. 4but: Crystal Structure of Human Tankyrase 2 in Complex with 4-(4- Oxo-3,4-dihydroquinazolin-2-yl)benzene-1-sulfonamide
176. 4buu: Crystal Structure of Human Tankyrase 2 in Complex with (4- (4-oxo-3,4-dihydroquinazolin-2-yl)phenyl)methanesulfonamide
177. 4buv: Crystal Structure of Human Tankyrase 2 in Complex with N-(4- (4-oxo-3,4-dihydroquinazolin-2-yl)phenyl)thiophene-2-carboxamide
178. 4buw: Crystal Structure of Human Tankyrase 2 in Complex with 2-(4- (2-oxo-1,3-oxazolidin-3-yl)phenyl)-3,4- Dihydroquinazolin-4-one
179. 4bux: Crystal Structure of Human Tankyrase 2 in Complex with 3-(( 4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl)methyl) Imidazolidine-2,4-dione
180. 4buy: Crystal Structure of Human Tankyrase 2 in Complex with 5- Methyl-5-(4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl) Imidazolidine-2,4-dione
181. 4krs: Tankyrase-1 Complexed with Small Molecule Inhibitor
182. 4kzl: Crystal Structure of Human Tankyrase 2 in Complex with 4'-fluoro Flavone
183. 4kzq: Crystal Structure of Human Tankyrase 2 in Complex with 4' -hydroxy Flavone
184. 4kzu: Crystal Structure of Human Tankyrase 2 in Complex with 4' -bromo Flavone
185. 4l09: Crystal Structure of Human Tankyrase 2 in Complex with 4-(4-oxo-4h- Chromen-2-yl)benzoic Acid
186. 4l0b: Tankyrase 2 in Complex with 4'-dimethylamino Flavone
187. 4l0i: Tankyrase 2 Catalytic Domain in Complex with Ethyl 4-(4-oxo-4h- Chromen-2-yl)benzoate
188. 4l0s: Tankyrase 2 in Complex with 4'-cyano Flavone
189. 4l0t: Tankyrase 2 in Complex with 4'-nitro Flavone
190. 4l0v: Tankyrase 2 in Complex with 4'-chloro Flavone
191. 4l10: Tankyrase 2 in Complex with 4'-methoxy Flavone
192. 4l2f: Tankyrase 2 in Complex with 6-chloro Flavone
193. 4l2g: Tankyrase 2 in Complex with 6- Fluoro Flavone
194. 4l2k: Tankyrase 2 in Complex with 2-(1,3-benzodioxol-5-yl)-4h-chromen-4-one
195. 4l31: Tankyrase 2 in Complex with Methyl 4-(4-oxochromen-2-yl)benzoate
196. 4l32: Tankyrase 2 in Complex with 2-[4-(4-methylpiperazine-1-carbonyl) Phenyl]chromen-4-one
197. 4l33: Tankyrase 2 in Complex with Cyanomethyl 4-(4-oxo-4h-chromen-2-yl) Benzoate
198. 4l34: Tankyrase 2 in Complex with 4'-tetrazole Flavone
199. 4l6z: Human Artd3 (parp3) - Catalytic Domain in Complex with Inhibitor Sto1168
200. 4l70: Human Artd3 (parp3) - Catalytic Domain in Complex with Inhibitor Me0352
201. 4l7l: Human Artd3 (parp3) - Catalytic Domain in Complex with Inhibitor Me0368
202. 4l7n: Human Artd3 (parp3) - Catalytic Domain in Complex with Inhibitor Sto1542
203. 4l7o: Human Artd3 (parp3) - Catalytic Domain in Complex with Inhibitor Sto1542
204. 4l7p: Human Artd3 (parp3) - Catalytic Domain in Complex with Inhibitor Me0395
205. 4l7r: Human Artd3 (parp3) - Catalytic Domain in Complex with Inhibitor Me0400
206. 4l7u: Human Artd3 (parp3) - Catalytic Domain in Complex with Inhibitor Me0398
207. 4li6: Tankyrase-1 Complexed with Small Molecule Inhibitor N-[(4-oxo-3,4- Dihydroquinazolin-2-yl)methyl]-3-phenyl-n-(thiophen-2-ylmethyl) Propanamide
208. 4li7: Tankyrase-1 Complexed with Small Molecule Inhibitor 4-chloro-5-cyano- N-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-2-methoxybenzamide
209. 4li8: Tankyrase-1 Complexed with Small Molecule Inhibitor 2-[4-(4- Fluorobenzoyl)piperidin-1-yl]-n-[(4-oxo-3,5,7,8-tetrahydro-4h- Pyrano[4,3-d]pyrimidin-2-yl)methyl]-n-(thiophen-2-ylmethyl)acetamide
210. 4m7b: Human Tankyrase 2 - Catalytic Parp Domain in Complex with an Inhibitor Upf1854
211. 4msg: Crystal Structure of Tankyrase 1 with Compound 22
212. 4msk: Co-crystal Structure of Tankyrase 1 with Compound 34
213. 4mt9: Co-crystal Structure of Tankyrase 1 with Compound 49
214. 4n3r: Co-crystal Structure of Tankyrase 1 with Compound 2 (5-(2- Aminoquinazolin-6-yl)-n-(4,4-dimethyl-2-oxo-1,2,3,4- Tetrahydroquinolin-7-yl)-2-fluorobenzamide)
215. 4n4t: Co-crystal Structure of Tankyrase 1 with Compound 3 [(4s)-3-{4-[6- Amino-5-(pyrimidin-2-yl)pyridin-3-yl]phenyl}-5,5-dimethyl-4-phenyl-1, 3-oxazolidin-2-one]
216. 4n4v: Co-crystal Structure of Tankyrase 1 with Compound 4 [(4s)-3-{trans-4- [6-amino-5-(pyrimidin-2-yl)pyridin-3-yl]cyclohexyl}-5,5-dimethyl-4- Phenyl-1,3-oxazolidin-2-one]
217. 4opx: Structure of Human Parp-1 Bound to a Dna Double Strand Break in Complex with (2r)-5-fluoro-2-methyl-2,3-dihydro-1-benzofuran-7- Carboxamide
218. 4oqa: Structure of Human Parp-1 Bound to a Dna Double Strand Break in Complex with (2z)-2-(2,4-dihydroxybenzylidene)-3-oxo-2,3-dihydro-1- Benzofuran-7-carboxamide
219. 4oqb: Structure of Human Parp-1 Bound to a Dna Double Strand Break in Complex with (2z)-2-{4-[2-(morpholin-4-yl)ethoxy]benzylidene}-3-oxo- 2,3-dihydro-1-benzofuran-7-carboxamide
220. 4pjt: Structure of Parp1 Catalytic Domain Bound to Inhibitor Bmn 673
221. 4pjv: Structure of Parp2 Catalytic Domain Bound to Inhibitor Bmn 673
222. 4pml: Crystal Structure of Human Tankyrase 2 in Complex with 3-amino- Benzamide.
223. 4pnl: Crystal Structure of Tnks-2 in Complex with Dr2313.
224. 4pnm: Crystal Structure of Human Tankyrase 2 in Complex with Nu1025.
225. 4pnn: Crystal Structure of Human Tankyrase 2 in Complex with 4hqn.
226. 4pnq: Crystal Structure of Human Tankyrase 2 in Complex with 5aiq.
227. 4pnr: Crystal Structure of Human Tankyrase 2 in Complex with Tiq-a.
228. 4pns: Crystal Structure of Human Tankyrase 2 in Complex with INH2BP.
229. 4pnt: Crystal Structure of Human Tankyrase 2 in Complex with 1,5-iqd.
230. 5xsu: Novel Orally Efficacious Inhibitors Complexed with Parp1
231. 5xst: Novel Orally Efficacious Inhibitors Complexed with Parp1
232. 5xsr: Novel Orally Efficacious Inhibitors Complexed with Parp1
233. 5wtc: Structure of Human Parp1 Catalytic Domain Bound to a Quinazoline-2, 4(1h,3h)-dione Inhibitor
234. 5ws1: Structure of Human Parp1 Catalytic Domain Bound to a Benzoimidazole Inhibitor
235. 5ws0: Structure of Human Parp1 Catalytic Domain Bound to a Benzoimidazole Inhibitor
236. 5wrz: Structure of Human Parp1 Catalytic Domain Bound to a Phthalazinone Inhibitor
237. 5wry: Structure of Human Parp1 Catalytic Domain Bound to a Quinazoline-2, 4(1h,3h)-dione Inhibitor
238. 5wrq: Structure of Human Parp1 Catalytic Domain Bound to a Quinazoline-2, 4(1h,3h)-dione Inhibitor
239. 4tju: Crystal Structure of Human Tankyrase 2 in Complex with 3,4-cpq-5-c.
240. 4tjw: Crystal Structure of Human Tankyrase 2 in Complex with Pj-34.
241. 4tjy: Crystal Structure of Human Tankyrase 2 in Complex with Abt-888.
242. 4tk0: Crystal Structure of Human Tankyrase 2 in Complex with Dpq.
243. 4tk5: Crystal Structure of Human Tankyrase 2 in Complex with Eb47.
244. 4tkf: Crystal Structure of Human Tankyrase 2 in Complex with Iwr-1.
245. 4tkg: Crystal Structure of Human Tankyrase 2 in Complex with Azd2281.
246. 4tki: Crystal Structure of Human Tankyrase 2 in Complex with Bsi-201.
247. 5v7w: Crystal Structure of Human Parp14 Bound to 2-{[(1-methylpiperidin-4- Yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin- 4(3h)-one Inhibitor
248. 5v7t: Crystal Structure of Parp14 Bound to N-{4-[4-(diphenylmethoxy) Piperidin-1-yl]butyl}[1,2,4]triazolo[4,3-b]pyridazin-6-amine Inhibitor
249. 5qia: Pandda Analysis Group Deposition of Models with Modelled Events (e.g. Bound Ligands) -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000242A
250. 5qi8: Pandda Analysis Group Deposition -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000605A
251. 5qi7: Pandda Analysis Group Deposition of Models with Modelled Events (e.g. Bound Ligands) -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000506A
252. 5qi5: Pandda Analysis Group Deposition of Models with Modelled Events (e.g. Bound Ligands) -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000633A
253. 5qi4: Pandda Analysis Group Deposition -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000466A
254. 5qi3: Pandda Analysis Group Deposition of Models with Modelled Events (e.g. Bound Ligands) -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000475A
255. 5qi2: Pandda Analysis Group Deposition of Models with Modelled Events (e.g. Bound Ligands) -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000110A
256. 5qi1: Pandda Analysis Group Deposition of Models with Modelled Events (e.g. Bound Ligands) -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000474A
257. 5qi0: Pandda Analysis Group Deposition of Models with Modelled Events (e.g. Bound Ligands) -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000352A
258. 5qhz: Pandda Analysis Group Deposition of Models with Modelled Events (e.g. Bound Ligands) -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000385A
259. 5qhy: Pandda Analysis Group Deposition of Models with Modelled Events (e.g. Bound Ligands) -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000462A
260. 5qhx: Pandda Analysis Group Deposition of Models with Modelled Events (e.g. Bound Ligands) -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000278A
261. 5qhw: Pandda Analysis Group Deposition of Models with Modelled Events (e.g. Bound Ligands) -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000347A
262. 5qhv: Pandda Analysis Group Deposition -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000299A
263. 5qhu: Pandda Analysis Group Deposition of Models with Modelled Events (e.g. Bound Ligands) -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMSOA000341B
264. 5qht: Pandda Analysis Group Deposition -- Crystal Structure of Human Parp14 Macrodomain 3 in Complex with FMOPL000065A
265. 5owt: Crystal Structure of Tnks2 in Complex with (5s)-5-methyl-5-[4-(4-oxo- 3,4-dihydroquinazolin-2-yl)phenyl]imidazolidine-2,4-dione
266. 5ows: Crystal Structure of Tnks2 in Complex with 2-[4-(4-methyl-2- Oxoimidazolidin-4-yl)phenyl]-3,4-dihydroquinazolin-4-one
267. 5o2d: Parp14 Macrodomain 2 with Inhibitor
268. 5nxe: Crystal Structure of Tnks2 in Complex with 2-{4-[(2-hydroxyethyl) (methyl)amino]phenyl}-1,2,3,4-tetrahydroquinazolin-4-one
269. 5nwg: Crystal Structure of Tnks2 in Complex with 7-chloro-2-{4-[(2- Hydroxyethyl)(methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one
270. 5nwd: Crystal Structure of Tnks2 in Complex with 2-[4-(diethylamino)phenyl]- 3,4-dihydroquinazolin-4-one
271. 5nwc: Crystal Structure of Tnks2 in Complex with 2-(2-aminophenyl)-3,4- Dihydroquinazolin-4-one
272. 5nwb: Crystal Structure of Tnks2 in Complex with 2-{4-[(2-hydroxyethyl) (methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one
273. 5nvh: Crystal Structure of Tnks2 in Complex with 2-[4-(piperidin-1-yl) Phenyl]-3,4-dihydroquinazolin-4-one
274. 5nvf: Crystal Structure of Tnks2 in Complex with 2-[4-(pyridin-2-yl)phenyl]- 3,4-dihydroquinazolin-4-one
275. 5nve: Crystal Structure of Tnks2 in Complex with 2-(4-ethoxyphenyl)-3,4- Dihydroquinazolin-4-one
276. 5nvc: Crystal Structure of Tnks2 in Complex with 2-(3-hydroxyphenyl)-3,4- Dihydroquinazolin-4-one
277. 5nut: Crystal Structure of Tnks2 in Complex with 2-[4-(propan-2-yloxy) Phenyl]-3,4-dihydroquinazolin-4-one
278. 5nt4: Crystal Structure of Tnks2 in Complex with 2-[4-(morpholin-4-yl) Phenyl]-3,4-dihydroquinazolin-4-one
279. 5nt0: Crystal Structure of Tnks2 in Complex with 2-(3-aminophenyl)-3,4- Dihydroquinazolin-4-one
280. 5nsx: Crystal Structure of Tnks2 in Complex with 2-(1h-indazol-5-yl)-3,4- Dihydroquinazolin-4-one
281. 5nsp: Crystal Structure of Tnks2 in Complex with Od334
282. 5nqe: Human Parp14 (artd8), Catalytic Fragment in Complex with an N-aryl Piperazine Inhibitor
283. 5nob: Crystal Structure of Human Tankyrase 2 in Complex with Od336
284. 5lyh: Human Parp14 (artd8), Catalytic Fragment in Complex with Inhibitor H10
285. 5lxp: Human Parp14 (artd8), Catalytic Fragment in Complex with Inhibitor H5
286. 5lx6: Human Parp10 (artd10), Catalytic Fragment in Complex with Parp Inhibitor Veliparib
287. 5kpq: Structure of Human Parp1 Catalytic Domain Bound to a Quinazoline-2, 4(1h,3h)-dione Inhibitor
288. 5kpp: Structure of Human Parp1 Catalytic Domain Bound to a Quinazoline-2, 4(1h,3h)-dione Inhibitor
289. 5kpo: Structure of Human Parp1 Catalytic Domain Bound to a Quinazoline-2, 4(1h,3h)-dione Inhibitor
290. 5kpn: Structure of Human Parp1 Catalytic Domain Bound to a Quinazoline-2, 4(1h,3h)-dione Inhibitor
291. 5kni: Crystal Structure of The Wild-type Sam Domain of Human Tankyrase-1
292. 5ju5: Crystal Structure of The Human Tankyrase 1 (tnks) Sam Domain (D1055R), Crystal Form 1
293. 5jti: Crystal Structure of The Human Tankyrase 1 (tnks) Sam Domain (D1055R), Crystal Form 2
294. 5jrt: Crystal Structure of The Human Tankyrase 2 (tnks2) Sam Domain (dh902/924re)
295. 5jhq: Arcs 1-3 of Human Tankyrase-1 Bound to a Peptide Derived from Irap
296. 5hkp: Crystal Structure of Mouse Tankyrase/human Trf1 Complex
297. 5ha9: Crystal Structure-based Design and Disovery of a Novel Parp1 Antiagonist (bl-pa10) That Induces Apoptosis and Inhibits Metastasis in Triple Negative Breast Cancer
298. 5gp7: Structural Basis for The Binding between Tankyrase-1 and Usp25
299. 5ety: Crystal Structure of Human Tankyrase-1 Bound to K-756
300. 5ece: Tankyrase 1 with Phthalazinone 1
301. 5ebt: Tankyrase 1 with Phthalazinone 2
302. 5dzq: C3LARVIN Toxin, an Adp-ribosyltransferase from Paenibacillus Larvae, Orthorhombic Form
303. 5dsy: Crystal Structure of Constitutively Active Parp-2
304. 5ds3: Crystal Structure of Constitutively Active Parp-1
305. 5dcz: Tankyrase 2 Complexed with a Selective Inhibitor
306. 5d5k: Crystal Structure Nls from Human Parp-2 Complexed with Importin Alpha Delta Ibb
307. 5c5r: Crystal Structure of Human Tankyrase-2 in Complex with a Pyranopyridone Inhibitor
308. 5c5q: Crystal Structure of Human Tankyrase-2 in Complex with a Pyranopyridone Inhibitor
309. 5c5p: Crystal Structure of Human Tankyrase-2 in Complex with a Pyranopyridone Inhibitor
310. 5bxu: Human Tankyrase-2 in Complex with Macrocyclised Extended Peptide CP4N4M5
311. 5bxo: Human Tankyrase-2 in Complex with Macrocyclised Extended Peptide CP4N2M3
312. 4oa7: Crystal Structure of Tankyrase1 in Complex with Iwr1
313. 5al5: Crystal Structure of Tnks2 in Complex with 2-(4-((pyridin-4- Yl)methyl)piperazin-1-yl)-3,4,5,6,7,8-hexahydroquinazolin-4-one
314. 5al4: Crystal Structure of Tnks2 in Complex with 2-(4- Methylpiperazin-1-yl)-3,4,5,6,7,8-hexahydroquinazolin-4-one
315. 5al3: Crystal Structure of Tnks2 in Complex with 2-(2,4- Dichlorophenyl)-1-methyl-1h,2h,3h,4h-pyrido(2,3-d) Pyrimidin-4-one
316. 5al2: Crystal Structure of Tnks2 in Complex with 2-(4-(propan-2- Yl)phenyl)-1h,2h,3h,4h-pyrido(2,3-d)pyrimidin-4-one
317. 5al1: Crystal Structure of Tnks2 in Complex with 2-(4-tert- Butylphenyl)-1h,2h,3h,4h-pyrido(2,3-d)pyrimidin-4-one
318. 5akw: Crystal Structure of Tnks2 in Complex with 2-(4- Chlorophenyl)-1,2,3,4-tetrahydroquinazolin-4-one
319. 5aku: Crystal Structure of Tnks2 in Complex with 2-(4-tert- Butylphenyl)-1,2,3,4-tetrahydroquinazolin-4-one
320. 5aeh: Crystal Structure of Human Tankyrase 2 in Complex with Od332
321. 5a3c: Crystal Structure of The Adp-ribosylating Sirtuin (sirtm) from Streptococcus Pyogenes in Complex with Nad
322. 5a3b: Crystal Structure of The Adp-ribosylating Sirtuin (sirtm) from Streptococcus Pyogenes in Complex with Adp-ribose
323. 5a3a: Crystal Structure of The Adp-ribosylating Sirtuin (sirtm) from Streptococcus Pyogenes (apo Form)
324. 5a00: Structure of Human Parp1 Catalytic Domain Bound to an Isoindolinone Inhibitor
325. 4zzz: Structure of Human Parp1 Catalytic Domain Bound to an Isoindolinone Inhibitor
326. 4zzy: Structure of Human Parp2 Catalytic Domain Bound to an Isoindolinone Inhibitor
327. 4zzx: Structure of Parp2 Catalytic Domain Bound to an Isoindolinone Inhibitor
328. 4z9c: Ecpltab Oxidized
329. 4z68: Hybrid Structural Analysis of The Arp2/3 Regulator Arpin Identifies Its Acidic Tail as a Primary Binding Epitope
330. 4py4: Crystal Structure of Human Poly(adp-ribose) Polymerase 14, Catalytic Domain in Complex with an Inhibitor Xl2
331. 4tor: Crystal Structure of Tankyrase 1 with Iwr-8
332. 4tos: Crystal Structure of Tankyrase 1 with 355
333. 4w5s: Tankyrase in Complex with Compound
334. 4w6e: Human Tankyrase 1 with Small Molecule Inhibitor
335. 2n8a: 1h, 13c and 15n Chemical Shift Assignments and Solution Structure for Parp-1 F1F2 Domains in Complex with a Dna Single-strand Break
336. 4r5w: Human Artd1 (parp1) - Catalytic Domain in Complex with Inhibitor Xav939
337. 4r6e: Human Artd1 (parp1) - Catalytic Domain in Complex with Inhibitor Niraparib
338. 4rv6: Human Artd1 (parp1) Catalytic Domain in Complex with Inhibitor Rucaparib
339. 4tvj: Human Artd2 (parp2) - Catalytic Domain in Complex with Olaparib
340. 4u6a: X-ray Crystal Structure of Human Tnks in Complex with a Small Molecule Inhibitor
341. 4ufu: Crystal Structure of Human Tankyrase 2 in Complex with Ta-12
342. 4ufy: Crystal Structure of Human Tankyrase 2 in Complex with Ta-13
343. 4uhg: Crystal Structure of Human Tankyrase 2 in Complex with Ta-21
344. 4ui3: Crystal Structure of Human Tankyrase 2 in Complex with Ta-26
345. 4ui4: Crystal Structure of Human Tankyrase 2 in Complex with Ta-29
346. 4ui5: Crystal Structure of Human Tankyrase 2 in Complex with Ta-41
347. 4ui6: Crystal Structure of Human Tankyrase 2 in Complex with Ta-47
348. 4ui7: Crystal Structure of Human Tankyrase 2 in Complex with Ta-49
349. 4ui8: Crystal Structure of Human Tankyrase 2 in Complex with Ta-55
350. 4und: Human Artd1 (parp1) - Catalytic Domain in Complex with Inhibitor Talazoparib
351. 4uuh: X-ray Crystal Structure of Human Tnks in Complex with a Small Molecule Inhibitor
352. 4uvl: Crystal Structure of Human Tankyrase 2 in Complex with 5-amino-1,2- Dihydroisoquinolin-1-one
353. 4uvn: Crystal Structure of Human Tankyrase 2 in Complex with 5-amino-3-(4- Chlorophenyl)-1,2-dihydroisoquinolin-1-one
354. 4uvo: Crystal Structure of Human Tankyrase 2 in Complex with 5-amino-3-(4- Methoxyphenyl)-1,2-dihydroisoquinolin-1-one
355. 4uvs: Crystal Structure of Human Tankyrase 2 in Complex with 5-amino-3- Pentyl-1,2-dihydroisoquinolin-1-one
356. 4uvt: Crystal Structure of Human Tankyrase 2 in Complex with 5-amino-4- Methyl-1,2-dihydroisoquinolin-1-one
357. 4uvu: Crystal Structure of Human Tankyrase 2 in Complex with 1-((4-(5- Methyl-1-oxo-1,2-dihydroisoquinolin-3-yl)phenyl)methyl)pyrrolidin-1- Ium
358. 4uvv: Crystal Structure of Human Tankyrase 2 in Complex with 3-(4- Chlorophenyl)-5-methyl-1,2-dihydroisoquinolin-1-one
359. 4uvw: Crystal Structure of Human Tankyrase 2 in Complex with 4,5-dimethyl-3- Phenyl-1,2-dihydroisoquinolin-1-one
360. 4uvx: Crystal Structure of Human Tankyrase 2 in Complex with 3-(4- Chlorophenyl)-5-fluoro-1,2-dihydroisoquinolin-1-one
361. 4uvy: Crystal Structure of Human Tankyrase 2 in Complex with 3-(4- Chlorophenyl)-5-methoxy-1,2- Dihydroisoquinolin-1-one
362. 4uvz: Crystal Structure of Human Tankyrase 2 in Complex with 5-amino-3- Phenyl-1,2-dihydroisoquinolin-1-one
363. 4uw1: X-ray Crystal Structure of Human Tnks in Complex with a Small Molecule Inhibitor
364. 4ux4: Crystal Structure of Human Tankyrase 2 in Complex with 1-methyl-7-(4- Methylphenyl)-5-oxo-5,6-dihydro-1,6-naphthyridin-1-ium
365. 4uxb: Human Artd1 (parp1) - Catalytic Domain in Complex with Inhibitor Pj34
366. 4w5i: Crystal Structure of Human Tankyrase 2 in Complex with 1-methyl-7- Phenyl-1,2,3,4,5,6-hexahydro-1,6- Naphthyridin-5-one
367. 4xhu: The Complex Structure of Timeless_pab and Parp-1_catalytic Domain
368. 7aaa: Crystal Structure of The Catalytic Domain of Human Parp1 (apo)
369. 7aab: Crystal Structure of The Catalytic Domain of Human Parp1 in Complex with Inhibitor Eb-47
370. 7aac: Crystal Structure of The Catalytic Domain of Human Parp1 in Complex with Veliparib
371. 7aad: Crystal Structure of The Catalytic Domain of Human Parp1 in Complex with Olaparib
372. 7kk2: Structure of The Catalytic Domain of Parp1
373. 7kk3: Structure of The Catalytic Domain of Parp1 in Complex with Talazoparib
374. 7kk4: Structure of The Catalytic Domain of Parp1 in Complex with Olaparib
375. 7kk5: Structure of The Catalytic Domain of Parp1 in Complex with Niraparib
376. 7kk6: Structure of The Catalytic Domain of Parp1 in Complex with Veliparib
377. 6m3i: Crystal Structure of Hpf1/parp1 Complex
378. 7ce4: Tankyrase2 Catalytic Domain in Complex with K-476
379. 7aeo: Human Artd2 in Complex with Dna Oligonucleotides
380. 7onr: Parp1 Catalytic Domain in Complex with 8-chloroquinazolinone-based Inhibitor (compound 9)
381. 7ons: Parp1 Catalytic Domain in Complex with Isoquinolone-based Inhibitor (compound 16)
382. 7ont: Parp1 Catalytic Domain in Complex with a Selective Pyridine Carboxamide-based Inhibitor (compound 22)