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enzyme (lysozyme)

 
Enzymes
  Enzyme classes:
  EC 1: Oxidoreductases
  EC 2: Transferases
    EC 2.1
    EC 2.2
    EC 2.3
    EC 2.4
      EC 2.4.1
      EC 2.4.2
        EC 2.4.2.1
        EC 2.4.2.2
        EC 2.4.2.3
        EC 2.4.2.4
        EC 2.4.2.5
        EC 2.4.2.6
        EC 2.4.2.7
        EC 2.4.2.8
        EC 2.4.2.9
        EC 2.4.2.10
        EC 2.4.2.11
        EC 2.4.2.12
        EC 2.4.2.13
        EC 2.4.2.14
        EC 2.4.2.15
        EC 2.4.2.16
        EC 2.4.2.17
        EC 2.4.2.18
        EC 2.4.2.19
        EC 2.4.2.20
        EC 2.4.2.21
        EC 2.4.2.22
        EC 2.4.2.23
        EC 2.4.2.24
        EC 2.4.2.25
        EC 2.4.2.26
        EC 2.4.2.27
        EC 2.4.2.28
        EC 2.4.2.29
        EC 2.4.2.30
        EC 2.4.2.31
        EC 2.4.2.32
        EC 2.4.2.33
        EC 2.4.2.34
        EC 2.4.2.35
        EC 2.4.2.36
        EC 2.4.2.37
        EC 2.4.2.38
        EC 2.4.2.39
        EC 2.4.2.40
      EC 2.4.99
    EC 2.5
    EC 2.6
    EC 2.7
    EC 2.8
    EC 2.9
  EC 3: Hydrolases
  EC 4: Lyases
  EC 5: Isomerases
  EC 6: Ligases
  General information:
  Catalytic mechanism
  Enzyme kinetics
  Inhibitors
  Enzymes in industry

EC 2.4.2.8 - IMP:diphosphate phospho- D- ribosyltransferase (hypoxanthine phosphoribosyltransferase)



3D structures of EC 2.4.2.8 - hypoxanthine phosphoribosyltransferase in Protein Data Bank

updated: 6 January 2022, 2:15

In total: 85 PDB structures of EC 2.4.2.8 - hypoxanthine phosphoribosyltransferase:
  1. 1bzy: Human Hgprtase with Transition State Inhibitor
  2. 1cjb: Malarial Purine Phosphoribosyltransferase
  3. 1d6n: Ternary Complex Structure of Human Hgprtase, Prpp, Mg2+, and The Inhibitor Hpp Reveals The Involvement of The Flexible Loop in Substrate Binding
  4. 1dqn: Crystal Structure of Giardia Guanine Phosphoribosyltransferase Complexed with a Transition State Analogue
  5. 1dqp: Crystal Structure of Giardia Guanine Phosphoribosyltransferase Complexed with Immucilling
  6. 1fsg: Toxoplasma Gondii Hypoxanthine-guanine Phosphoribosyltransferase Complexed with 9-deazaguanine, Alpha-d-5-phosphoribosyl-1-pyrophosphate (prpp) and Two Mg2+ Ions
  7. 1g9s: Crystal Structure of a Complex between E.coli Hprt and Imp
  8. 1g9t: Crystal Structure of E.coli Hprt-gmp Complex
  9. 1grv: Hypoxanthine Phosphoribosyltransferase from E. Coli
  10. 1hgx: Hypoxanthine-guanine-xanthine Phosphoribosyltransferase (hgxprtase)
  11. 1hmp: The Crystal Structure of Human Hypoxanthine-guanine Phosphoribosyltransferase with Bound Gmp
  12. 1i0i: Analysis of an Invariant Aspartic Acid in Hprts-glutamine Mutant
  13. 1i0l: Analysis of an Invariant Aspartic Acid in Hprts-asparagine Mutant
  14. 1i13: Analysis of an Invariant Aspartic Acid in Hprts-alanine Mutant
  15. 1i14: Analysis of an Invariant Aspartic Acid in Hprts-glutamic Acid Mutant
  16. 1j7j: Crystal Structure of The Hprt from Salmonella Typhimurium
  17. 3ohp: Crystal Structure of Hgprt from Vibrio Cholerae
  18. 3o7m: 1.98 Angstrom Resolution Crystal Structure of a Hypoxanthine-guanine Phosphoribosyltransferase (hpt-2) from Bacillus Anthracis Str. 'ames Ancestor'
  19. 3kb8: 2.09 Angstrom Resolution Structure of a Hypoxanthine-guanine Phosphoribosyltransferase (hpt-1) from Bacillus Anthracis Str. 'ames Ancestor' in Complex with Gmp
  20. 1p17: Hypoxanthine Phosphoribosyltransferase from Trypanosoma Cruzi, K68R Mutant, Complexed with The Product Imp
  21. 1p18: Hypoxanthine Phosphoribosyltransferase from Trypanosoma Cruzi, K68R Mutant, Ternary Substrates Complex
  22. 1p19: Hypoxanthine Phosphoribosyltransferase from Trypanosoma Cruzi, in Complex with The Product Imp
  23. 1pzm: Crystal Structure of Hgprt-ase from Leishmania Tarentolae in Complex with Gmp
  24. 1qk3: Toxoplasma Gondii Hypoxanthine-guanine Phosphoribosyltransferase Gmp Complex
  25. 1qk4: Toxoplasma Gondii Hypoxanthine-guanine Phosphoribosyltransferase Imp Complex
  26. 1qk5: Toxoplasma Gondii Hypoxanthine-guanine Phosphoribosyltransferase with Xmp, Pyrophosphate and Two Mg2+ Ions
  27. 1r3u: Crystal Structure of Hypoxanthine-guanine Phosphoribosyltransferase from Thermoanaerobacter Tengcongensis
  28. 3ggj: Human Hypoxanthine-guanine Phosphoribosyltransferase in Complex with 9-(2-phosphonoethoxyethyl)guanine
  29. 3ggc: Human Hypoxanthine-guanine Phosphoribosyltransferase in Complex with 9-(2-phosphonoethoxyethyl)hypoxanthine
  30. 3gep: Human Hypoxanthine Guanine Phosphoribosyltranserfase in Complex with (s)-9-(3-hydroxy-2-phosphonylmethoxypropyl) Guanine
  31. 1tc1: A 1.4 Angstrom Crystal Structure for The Hypoxanthine Phosphoribosyltransferase of Trypanosoma Cruzi
  32. 1tc2: Ternary Substrate Complex of The Hypoxanthine Phosphoribosyltransferase from Trypanosoma Cruzi
  33. 3acd: Crystal Structure of Hypoxanthine-guanine Phosphoribosyltransferase with Imp from Thermus Thermophilus Hb8
  34. 3acc: Crystal Structure of Hypoxanthine-guanine Phosphoribosyltransferase with Gmp from Thermus Thermophilus Hb8
  35. 3acb: Crystal Structure of Hypoxanthine-guanine Phosphoribosyltransferase from Thermus Thermophilus Hb8
  36. 1yfz: Novel Imp Binding in Feedback Inhibition of Hypoxanthine- Guanine Phosphoribosyltransferase from Thermoanaerobacter Tengcongensis
  37. 1z7g: Free Human Hgprt
  38. 2vfa: Crystal Structure of a Chimera of Plasmodium Falciparum and Human Hypoxanthine-guanine Phosphoribosyl Transferases
  39. 6bo7: Crystal Structure of Plasmodium Vivax Hypoxanthine Guanine Phosphoribosyltransferase in Complex with [3r,4r]-4-guanin-9-yl-3- ((s)-2-hydroxy-2-phosphonoethyl)oxy-1-n-(phosphonopropionyl) Pyrrolidine
  40. 6bnj: Human Hypoxanthine Guanine Phosphoribosyltransferase in Complex with [3r,4r]-4-guanin-9-yl-3-((r)-2-hydroxy-2-phosphonoethyl)oxy-1-n- (phosphonopropionyl)pyrrolidine
  41. 6apv: Trypanosoma Brucei Hypoxanthine Guanine Phosphoribosyltransferase in Complex with [(2-{[2-(2-amino-6-oxo-1,6-dihydro-9h-purin-9-yl) Ethyl][(e)-2-phosphonoethenyl]amino}ethoxy)methyl]phosphonic Acid
  42. 6apu: Crystal Structure of Trypanosoma Brucei Hypoxanthine-guanine Phosphoribosyltranferase in Complex with (2-{[2-(2-amino-6-oxo-1,6- Dihydro-9h-purin-9-yl)ethyl](3-aminopropyl)amino}ethyl)phosphonic Acid
  43. 6apt: Trypanosoma Brucei Hypoxanthine Guanine Phosphoribosyltransferase in Complex with {[(2s)-3-(2-amino-6-oxo-1,6-dihydro-9h-purin-9-yl) Propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic Acid)
  44. 6aps: Trypanosoma Brucei Hypoxanthine Guanine Phosphoribosyltransferase in Complex with [(2-((guanine-9h-yl)methyl)propane-1,3 Diyl)bis(oxy) ]bis(methylene))diphosphonic Acid
  45. 2geb: Crystal Structure of The Thermoanaerobacter Tengcongensis Hypoxanthine-guanine Phosphoribosyltransferase L160I Mutant: Insights into The Inhibitor Design
  46. 2jbh: Human Phosphoribosyl Transferase Domain Containing 1
  47. 2jky: Saccharomyces Cerevisiae Hypoxanthine-guanine Phosphoribosyltransferase in Complex with Gmp (guanosine 5' -monophosphate) (tetragonal Crystal Form)
  48. 2jkz: Saccharomyces Cerevisiae Hypoxanthine-guanine Phosphoribosyltransferase in Complex with Gmp (guanosine 5' -monophosphate) (orthorhombic Crystal Form)
  49. 2xbu: Saccharomyces Cerevisiae Hypoxanthine-guanine Phosphoribosyltransferase in Complex with Gmp (monoclinic Crystal Form)
  50. 6mxg: Crystal Structure of Trypanosoma Brucei Hypoxanthine-guanine Phosphoribosyltranferase in Complex with Xmp
  51. 6igs: Crystal Structure of Hprt from F. Tularensis with Zinc
  52. 4ijq: Human Hypoxanthine-guanine Phosphoribosyltransferase in Complex with [(2-((guanine-9h-yl)methyl)propane-1,3-diyl)bis(oxy)]bis(methylene)) Diphosphonic Acid
  53. 6d9s: The (p)ppgpp-bound Crystal Structure of Hprt (hypoxanthine Phosphoribosyltransferase)
  54. 6d9r: The Substrate-bound Crystal Structure of Hprt (hypoxanthine Phosphoribosyltransferase)
  55. 6d9q: The Sulfate-bound Crystal Structure of Hprt (hypoxanthine Phosphoribosyltransferase)
  56. 4kn6: Crystal Structure of Human Hypoxanthine-guanine Phosphoribosyltransferase in Complex with 6-fluoro-3-hydroxy-2- Pyrazinecarboxamide (t-705) Ribose-5'-monophosphate
  57. 4lyy: Crystal Structure of Hypoxanthine Phosphoribosyltransferase from Shewanella Pealeana Atcc 700345, Nysgrc Target 029677.
  58. 4pfq: Crystal Structure of Hypoxanthine Phosphoribosyltransferase from Brachybacterium Faecium Dsm 4810, Nysgrc Target 029763.
  59. 5w8v: Human Hgprt in Complex with [(2-[(guanin-9-yl)methyl]propane-1,3- Diyl)bis(oxy)]bis(methylene)diphosphonic Acid
  60. 4qri: 2.35 Angstrom Resolution Crystal Structure of Hypoxanthine-guanine- Xanthine Phosphoribosyltransferase from Leptospira Interrogans Serovar Copenhageni Str. Fiocruz L1-130
  61. 4qyi: 1.95 Angstrom Resolution Crystal Structure of a Hypoxanthine-guanine Phosphoribosyltransferase (hpt-2) from Bacillus Anthracis Str. 'ames Ancestor' with Hepes Molecule in The Active Site
  62. 4rqa: Crystal Structure of a Hypoxanthine Phosphoribosyltransferase (target Id Nysgrc-029686) from Staphylococcus Aureus (orthorhombic Space Group)
  63. 4rqb: Crystal Structure of a Hypoxanthine Phosphoribosyltransferase (target Id Nysgrc-029686) from Staphylococcus Aureus (tetragonal Space Group)
  64. 5kny: Crystal Structure of Mycobacterium Tuberculosis Hypoxanthine Guanine Phosphoribosyltransferase in Complex with (3-((3r,4r)-3-(guanin-9- Yl)-4-((s)-2-hydroxy-2-phosphonoethoxy)pyrrolidin-1-yl)-3-oxopropyl) Phosphonic Acid
  65. 5knq: Crystal Structure of Mycobacterium Tuberculosis Hypoxanthine Guanine Phosphoribosyltransferase in Complex with [3s,4r]-(4-(guanin-9-yl) Pyrrolidin-3-yl)oxymethanephosphonic Acid and Pyrophosphate
  66. 5knp: Crystal Structure of Mycobacterium Tuberculosis Hypoxanthine Guanine Phosphoribosyltransferase in Complex with [3s,4r]-(4-(hypoxanthin-9- Yl)pyrrolidin-3-yl)-oxymethanephosphonic Acid
  67. 5kap: Trypanosome Brucei Hypoxanthine-guanine Phosphoribosyltranferase in Complex with a 9-(4-(phosphonobutil)hypoxanthine
  68. 5kam: Trypanosome Brucei Hypoxanthine-guanine Phosphoribosyltranferase in Complex with Inosine 5' Monophosphate
  69. 5k51: Trypanosome Brucei Hypoxanthine-guanine Phosphoribosyltranferase in Complex with a 9-[5-(phosphonoheptyl]hypoxanthine
  70. 5jv5: Trypanosome Brucei Hypoxanthine-guanine Phosphoribosyltranferase in Complex with Guanosine 5' Monophosphate
  71. 5jsq: Trypanosome Brucei Hypoxanthine-guanine Phosphoribosyltranferase in Complex with a 9-[7-(phosphonoheptyl]guanine
  72. 5ipf: Crystal Structure of Hypoxanthine-guanine Phosphoribosyltransferase from Schistosoma Mansoni in Complex with Imp
  73. 5hia: Human Hypoxanthine-guanine Phosphoribosyltransferase in Complex with [3r,4r]-4-guanin-9-yl-3-((s)-2-hydroxy-2-phosphonoethyl)oxy-1-n- (phosphonopropionyl)pyrrolidine
  74. 5esw: Crystal Structure of Apo Hypoxanthine-guanine Phosphoribosyltransferase from Legionella Pneumophila
  75. 5bsk: Human Hgprt in Complex with (s)-hpepg, an Acyclic Nucleoside Phosphonate
  76. 5brn: Human Hgprt in Complex with (s)-hpephx, an Acyclic Nucleoside Phosphonate
  77. 5bqo: Hypoxanthine-guanine-xanthine Phosphoribosyltransferase (hgxprt) from Sulfolobus Solfataricus with Sulfate Bound in The 5-phosphoribosyl Binding Site.
  78. 4rab: Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group as Inhibitors of The Human, Plasmodium Falciparum and Vivax 6- Oxopurine Phosphoribosyltransferases and Their Pro-drugs as Antimalarial Agents
  79. 4rac: Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group as Inhibitors of The Human, Plasmodium Falciparum and Vivax 6- Oxopurine Phosphoribosyltransferases and Their Pro-drugs as Antimalarial Agents
  80. 4rad: Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group as Inhibitors of The Human, Plasmodium Falciparum and Vivax 6- Oxopurine Phosphoribosyltransferases and Their Pro-drugs as Antimalarial Agents
  81. 4ran: Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group as Inhibitors of The Human, Plasmodium Falciparum and Vivax 6- Oxopurine Phosphoribosyltransferases and Their Pro-drugs as Antimalarial Agents
  82. 4rao: Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group as Inhibitors of The Human, Plasmodium Falciparum and Vivax 6- Oxopurine Phosphoribosyltransferases and Their Pro-drugs as Antimalarial Agents
  83. 4raq: Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group as Inhibitors of The Human, Plasmodium Falciparum and Vivax 6- Oxopurine Phosphoribosyltransferases and Their Pro-drugs as Antimalarial Agents
  84. 4z1o: Hypoxanthine-guanine-xanthine Phosphoribosyltransferase (hgxprt) from Sulfolobus Solfataricus in Complex with Alpha- Phosphoribosylpyrophosphoric Acid (prpp) and Magnesium
  85. 7cmj: Crystal Structure of L.donovani Hypoxanthine-guanine Phosphoribosyl Transferase (hgprt)
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