EC 3.4.21.46 - complement factor D

3D structures of EC 3.4.21.46 - complement factor D in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1bio: Human Complement Factor D in Complex with Isatoic Anhydride Inhibitor
2. 1dfp: Factor D Inhibited by Diisopropyl Fluorophosphate
3. 1dic: Structure of 3,4-dichloroisocoumarin-inhibited Factor D
4. 1dst: Mutant of Factor D with Enhanced Catalytic Activity
5. 1dsu: Human Factor D, Complement Activating Enzyme
6. 1fdp: Proenzyme of Human Complement Factor D, Recombinant Profactor D
7. 1hfd: Human Complement Factor D in a P21 Crystal Form
8. 2xw9: Crystal Structure of Complement Factor D Mutant S183A
9. 2xwa: Crystal Structure of Complement Factor D Mutant R202A
10. 2xwb: Crystal Structure of Complement C3B in Complex with Factors B and D
11. 6qmt: Complement Factor D in Complex with The Inhibitor 2-(2-(3'- (aminomethyl)-[1,1'-biphenyl]-3-carboxamido)phenyl)acetic Acid
12. 6qmr: Complement Factor D in Complex with The Inhibitor (s)-2-(2-((3'-(1- Amino-2-hydroxyethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)acetic Acid
13. 4d9r: Inhibiting Alternative Pathway Complement Activation by Targeting The Exosite on Factor D
14. 6fut: Complement Factor D in Complex with The Inhibitor (s)-3'- (aminomethyl)-n-(1,2,3,4-tetrahydronaphthalen-1-yl)-[1,1'-biphenyl]- 3-carboxamide
15. 6fuj: Complement Factor D in Complex with The Inhibitor N-(3'-(aminomethyl)- [1,1'-biphenyl]-3-yl)-3-methylbutanamide
16. 6fui: Complement Factor D in Complex with The Inhibitor 3-((3-((3- (aminomethyl)phenyl)amino)-1h-pyrazolo[3,4-d]pyrimidin-4-yl)amino) Phenol
17. 6fuh: Complement Factor D in Complex with The Inhibitor (4-((3- (aminomethyl)phenyl)amino)quinazolin-2-yl)-l-valine
18. 6fug: Complement Factor D in Complex with The Inhibitor 3-((3-((3- (aminomethyl)phenyl)amino)-1h-pyrazolo[3,4-d]pyrimidin-4-yl)amino) Phenol
19. 6ftz: Complement Factor D Complexed with Compound 6
20. 6fty: Complement Factor D Complexed with Compound 5
21. 4cbn: Crystal Structure of Complement Factor D Mutant R202A after Conventional Refinement
22. 4cbo: Crystal Structure of Complement Factor D Mutant R202A after Ensemble Refinement
23. 5tcc: Complement Factor D Inhibited with Jh4
24. 5tca: Complement Factor D Inhibited with Jh3
25. 5nba: Complement Factor D in Complex with The Inhibitor (2s,4r)-4-fluoro- Pyrrolidine-1,2-dicarboxylic Acid 1-[(1-carbamoyl-1h-indol-3-yl)- Amide] 2-[(3-trifluoromethoxy-phenyl)-amide]
26. 5nb7: Complement Factor D
27. 5nb6: Complement Factor D in Complex with The Inhibitor (2s,4s)-4-amino- Pyrrolidine-1,2-dicarboxylic Acid 1-[(1-carbamoyl-1h-indol-3-yl)- Amide] 2-[(3-trifluoromethoxy-phenyl)-amide]
28. 5naw: Complement Factor D in Complex with The Inhibitor (1r,3s,5r)-2-aza- Bicyclo[3.1.0]hexane-2,3-dicarboxylic Acid 2-[(1-carbamoyl-1h-indol- 3-yl)-amide] 3-[(3-trifluoromethoxy-phenyl)-amide]
29. 5nat: Complement Factor D in Complex with The Inhibitor (s)-pyrrolidine-1,2- Dicarboxylic Acid 1-[(1-methyl-1h-indol-3-yl)-amide] 2-[(3- Trifluoromethoxy-phenyl)-amide]
30. 5nar: Complement Factor D in Complex with The Inhibitor (s)-pyrrolidine-1,2- Dicarboxylic Acid 1-[(1-carbamoyl-1h-indol-3-yl)-amide] 2-[(3- Trifluoromethoxy-phenyl)-amide]
31. 5mt4: Complement Factor D in Complex with a Reversible Benzoic Acid Based Inhibitor
32. 5mt0: Complement Factor D in Complex with a Reversible Indole Carboxylic Acid Based Inhibitor
33. 5fcr: Mouse Complement Factor D
34. 5fck: Complement Factor D in Complex with Compound 5
35. 5fbi: Complement Factor D in Complex with Compound 3b
36. 5fbe: Complement Factor D in Complex with Compound2
37. 6vmj: Crystal Structure of Human Complement Factor D with Anti-factor D Fab 20d12
38. 6vmk: Crystal Structure of Human Complement Factor D with Anti-factor D Fab 20d12