EC 3.4.23.15 - renin

3D structures of EC 3.4.23.15 - renin in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1bbs: X-ray Analyses of Peptide Inhibitor Complexes Define The Structural Basis of Specificity for Human and Mouse Renins
2. 1bil: Crystallographic Studies on The Binding Modes of P2-p3 Butanediamide Renin Inhibitors
3. 1bim: Crystallographic Studies on The Binding Modes of P2-p3 Butanediamide Renin Inhibitors
4. 3oqk: Crystal Structure Analysis of Renin-indole-piperazin Inhibitor Complexes
5. 3oqf: Crystal Structure Analysis of Renin-indole-piperazine Inhibitor Complexes
6. 3oot: Crystal Structure Analysis of Renin-indole-piperazin Inhibitor Complexes
7. 3oag: Design and Optimization of New Piperidines as Renin Inhibitors
8. 3oad: Design and Optimization of New Piperidines as Renin Inhibitors
9. 3km4: Optimization of Orally Bioavailable Alkyl Amine Renin Inhibitors
10. 3k1w: New Classes of Potent and Bioavailable Human Renin Inhibitors
11. 3gw5: Crystal Structure of Human Renin Complexed with a Novel Inhibitor
12. 1rne: The Crystal Structure of Recombinant Glycosylated Human Renin Alone and in Complex with a Transition State Analog Inhibitor
13. 3g72: Design and Preparation of Potent, Non-peptidic, Bioavailable Renin Inhibitors
14. 3g70: Design and Preparation of Potent, Non-peptidic, Bioavailable Renin Inhibitors
15. 3g6z: Design and Preparation of Potent, Non-peptidic, Bioavailable Renin Inhibitors
16. 1smr: The 3-d Structure of Mouse Submaxillary Renin Complexed with a Decapeptide Inhibitor Ch-66 Based on The 4-16 Fragment of Rat Angiotensinogen
17. 3d91: Human Renin in Complex with Remikiren
18. 2x0b: Crystal Structure of Human Angiotensinogen Complexed with Renin
19. 2v16: Crystal Structure of Renin with Inhibitor 3
20. 2v13: Crystal Structure of Renin with Inhibitor 7
21. 2v12: Crystal Structure of Renin with Inhibitor 8
22. 2v11: Crystal Structure of Renin with Inhibitor 6
23. 2v10: Crystal Structure of Renin with Inhibitor 9
24. 2v0z: Crystal Structure of Renin with Inhibitor 10 (aliskiren)
25. 2bks: Crystal Structure of Renin-pf00074777 Complex
26. 2bkt: Crystal Structure of Renin-pf00257567 Complex
27. 2ren: Structure of Recombinant Human Renin, a Target for Cardiovascular-active Drugs, at 2.5 Angstroms Resolution
28. 2fs4: Ketopiperazine-based Renin Inhibitors: Optimization of The C Ring
29. 2g1n: Ketopiperazine-based Renin Inhibitors: Optimization of The "c" Ring
30. 2g1o: Ketopiperazine-based Renin Inhibitors: Optimization of The "c" Ring
31. 2g1r: Ketopiperazine-based Renin Inhibitors: Optimization of The C Ring
32. 2g1s: Ketopiperazine-based Renin Inhibitors: Optimization of The C Ring
33. 2g1y: Ketopiperazine-based Renin Inhibitors: Optimization of The "c" Ring
34. 2g20: Ketopiperazine-based Renin Inhibitors: Optimization of The C Ring
35. 2g21: Ketopiperazine-based Renin Inhibitors: Optimization of The "c" Ring
36. 2g22: Ketopiperazine-based Renin Inhibitors: Optimization of The "c" Ring
37. 2g24: Ketopiperazine-based Renin Inhibitors: Optimization of The "c" Ring
38. 2g26: Ketopiperazine-based Renin Inhibitors: Optimization of The "c" Ring
39. 2g27: Ketopiperazine-based Renin Inhibitors: Optimization of The "c" Ring
40. 2i4q: Human Renin/pf02342674 Complex
41. 2iko: Crystal Structure of Human Renin Complexed with Inhibitor
42. 2iku: Crystal Structure of Human Renin Complexed with Inhibitors
43. 2il2: Crystal Structure of Human Renin Complexed with Inhibitor
44. 3o9l: Design and Optimisation of New Piperidines as Renin Inhibitors
45. 3own: Potent Macrocyclic Renin Inhibitors
46. 3q3t: Alkyl Amine Renin Inhibitors: Filling S1 from S3
47. 3sfc: Structure-based Optimization of Potent 4- and 6-azaindole-3- Carboxamides as Renin Inhibitors
48. 3q4b: Clinically Useful Alkyl Amine Renin Inhibitors
49. 3q5h: Clinically Useful Alkyl Amine Renin Inhibitors
50. 3vcm: Crystal Structure of Human Prorenin
51. 3vsw: Human Renin in Complex with Compound 8
52. 3vsx: Human Renin in Complex with Compound 18
53. 6i3f: Crystal Structure of The Complex of Human Angiotensinogen and Renin at 2.55 Angstrom
54. 3vyd: Human Renin in Complex with Inhibitor 6
55. 3vye: Human Renin in Complex with Inhibitor 7
56. 3vyf: Human Renin in Complex with Inhibitor 9
57. 4gj8: Crystal Structure of Renin in Complex with Pkf909-724 (compound 3)
58. 4gj9: Crystal Structure of Renin in Complex with Gp055321 (compound 4)
59. 4gja: Crystal Structure of Renin in Complex with Nvp-ayl747 (compound 5)
60. 4gjb: Crystal Structure of Renin in Complex with Nvp-bbv031 (compound 6)
61. 4gjc: Crystal Structure of Renin in Complex with Nvp-bch965 (compound 9)
62. 4gjd: Crystal Structure of Renin in Complex with Nvp-bgq311 (compound 12)
63. 4amt: Crystal Structure at 2.6a of Human Prorenin
64. 4gj5: Crystal Structure of Renin in Complex with Nvp-amq838 (compound 5)
65. 4gj6: Crystal Structure of Renin in Complex with Nvp-ayz832 (compound 6a)
66. 4gj7: Crystal Structure of Renin in Complex with Nvp-bca079 (compound 12a)
67. 3vuc: Human Renin in Complex with Compound 5
68. 4pyv: Crystal Structure of Renin in Complex with Compound4
69. 4q1n: Structure-based Design of 4-hydroxy-3,5-substituted Piperidines as Direct Renin Inhibitors
70. 5vrp: Crystal Structure of Human Renin in Complex with a Biphenylpipderidinylcarbinol
71. 5vpm: Crystal Structure of Human Renin in Complex with a Biphenylpipderidinylcarbinol
72. 5v8v: Crystal Structure of Human Renin in Complex with a Biphenylpipderidinylcarbinol
73. 5tmk: Optimization of 3,5-disubstitued Piperidine: Discovery of Non-peptide Mimetics as an Orally Active Renin Inhibitor
74. 5tmg: Optimization of 3,5-disubstitued Piperidine: Discovery of Non-peptide Mimetics as an Orally Active Renin Inhibitor
75. 5t4s: Novel Approach of Fragment-based Lead Discovery Applied to Renin Inhibitors
76. 5sz9: Structure-based Design of a New Series of N-piperidin-3-ylpyrimidine- 5-carboxamides as Renin Inhibitors
77. 5sy3: Structure-based Design of a New Series of N-piperidin-3-ylpyrimidine- 5-carboxamides as Renin Inhibitors
78. 5sy2: Structure-based Design of a New Series of N-piperidin-3-ylpyrimidine- 5-carboxamides as Renin Inhibitors
79. 5sxn: Structure-based Design of a New Series of N-piperidin-3-ylpyrimidine- 5-carboxamides as Renin Inhibitors
80. 5mlg: Crystal Structure of Rat Prorenin
81. 5mkt: Crystal Structure of Mouse Prorenin
82. 5kot: Discovery of Tak-272: a Novel, Potent and Orally Active Renin In- Hibitor
83. 5kos: Discovery of Tak-272: a Novel, Potent and Orally Active Renin In- Hibitor
84. 5koq: Discovery of Tak-272: a Novel, Potent and Orally Active Renin In- Hibitor
85. 4xx3: Renin in Complex with (s)-1-(3-(benzylcarbamoyl)benzyl)-4-isopropyl-4- Methyl-6-oxotetrahydropyrimidin-2(1h)-iminium
86. 4xx4: Renin in Complex with (4s)-4-isopropyl-4-methyl-6-oxo-1-(3-(2-oxo-4- Phenylpyrrolidin-1-yl)benzyl)tetrahydropyrimidin-2(1h)-iminium
87. 4s1g: Rein in Complex with (s)-1-(3-fluoro-5-(((s)-1-phenylethyl)carbamoyl) Benzyl)-4-isopropyl-4-methyl-6-oxotetrahydropyrimidin-2(1h)-iminium
88. 4ryc: Renin in Complexed with 4-methoxy-3-(3-methoxypropoxy)-n-{[(3s,4s)-4- {[(4-methylphenyl)sulfonyl]amino}pyrrolidin-3-yl]methyl}-n-(propan-2- Yl)benzamide Inhibitor
89. 4ryg: Renin in Complexed with N-({(3s,4s)-4-[(benzylsulfonyl) Amino]pyrrolidin-3-yl}methyl)-4-methoxy-3-(3-methoxypropoxy)-n- (propan-2-yl)benzamide Inhibitor
90. 4rz1: Renin in Complexed with (3s,4s)-4-({[4-methoxy-3-(3-methoxypropoxy) Benzoyl](propan-2-yl)amino}methyl)pyrrolidin-3-yl Benzylcarbamate Inhibitor