EC 3.4.24.27 - thermolysin

3D structures of EC 3.4.24.27 - thermolysin in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1bqb: Aureolysin, Staphylococcus Aureus Metalloproteinase
2. 1fj3: Thermolysin (50% Acetone Soaked)
3. 1fjo: Thermolysin (60% Acetone Soaked Crystals)
4. 1fjq: Thermolysin (70% Acetone Soaked Crystals)
5. 1fjt: Thermolysin (50% Acetonitrile Soaked Crystals)
6. 1fju: Thermolysin (80% Acetonitrile Soaked Crystals)
7. 1fjv: Thermolysin (60% Acetonitrile Soaked Crystals)
8. 1fjw: Thermolysin (50 Mm Phenol Soaked)
9. 1gxw: The 2.2 a Resolution Structure of Thermolysin Crystallized in Presence of Potassium Thiocyanate
10. 1hyt: Re-determination and Refinement of The Complex of Benzylsuccinic Acid with Thermolysin and Its Relation to The Complex with Carboxypeptidase a
11. 8tln: Structural Comparison Suggests That Thermolysin and Related Neutral Proteases Undergo Hinge-bending Motion during Catalysis
12. 8tli: Thermolysin (100% Isopropanol Soaked Crystals)
13. 7tln: Structural Analysis of The Inhibition of Thermolysin by an Active-site-directed Irreversible Inhibitor
14. 7tli: Thermolysin (90% Isopropanol Soaked Crystals)
15. 6tmn: Structures of Two Thermolysin-inhibitor Complexes That Differ by a Single Hydrogen Bond
16. 6tli: Thermolysin (60% Isopropanol Soaked Crystals)
17. 5tmn: Slow-and Fast-binding Inhibitors of Thermolysin Display Different Modes of Binding. Crystallographic Analysis of Extended Phosphonamidate Transition-state Analogues
18. 5tln: Binding of Hydroxamic Acid Inhibitors to Crystalline Thermolysin Suggests a Pentacoordinate Zinc Intermediate in Catalysis
19. 5tli: Thermolysin (60% Isopropanol Soaked Crystals)
20. 4tmn: Slow-and Fast-binding Inhibitors of Thermolysin Display Different Modes of Binding. Crystallographic Analysis of Extended Phosphonamidate Transition-state Analogues
21. 4tln: Binding of Hydroxamic Acid Inhibitors to Crystalline Thermolysin Suggests a Pentacoordinate Zinc Intermediate in Catalysis
22. 4tli: Thermolysin (25% Isopropanol Soaked Crystals)
23. 1kei: Thermolysin (substrate-free)
24. 3tmn: The Binding of L-valyl-l-tryptophan to Crystalline Thermolysin Illustrates The Mode of Interaction of a Product of Peptide Hydrolysis
25. 3tli: Thermolysin (10% Isopropanol Soaked Crystals)
26. 1kjo: Thermolysin Complexed with Z-l-threonine (benzyloxycarbonyl- L-threonine)
27. 1kjp: Thermolysin Complexed with Z-l-glutamic Acid (benzyloxycarbonyl-l-glutamic Acid)
28. 1kkk: Thermolysin Complexed with Z-l-aspartic Acid (benzyloxycarbonyl-l-aspartic Acid)
29. 1kl6: Thermolysin Complexed with Z-l-alanine (benzyloxycarbonyl-l- Alanine)
30. 1kr6: Thermolysin Complexed with Z-d-glutamic Acid (benzyloxycarbonyl-d-glutamic Acid)
31. 1kro: Thermolysin Complexed with Z-d-threonine (benzyloxycarbonyl- D-threonine)
32. 1ks7: Thermolysin Complexed with Z-d-aspartic Acid (benzyloxycarbonyl-d-aspartic Acid)
33. 1kto: Thermolysin Complexed with Z-d-alanine (benzyloxycarbonyl-d- Alanine)
34. 1l3f: Thermolysin in The Absence of Substrate Has an Open Conformation
35. 1lna: A Structural Analysis of Metal Substitutions in Thermolysin
36. 1lnb: A Structural Analysis of Metal Substitutions in Thermolysin
37. 1lnc: A Structural Analysis of Metal Substitutions in Thermolysin
38. 1lnd: A Structural Analysis of Metal Substitutions in Thermolysin
39. 1lne: A Structural Analysis of Metal Substitutions in Thermolysin
40. 1lnf: A Structural Analysis of Metal Substitutions in Thermolysin
41. 1npc: The Structure of Neutral Protease from Bacillus Cereus at 0.2-nm Resolution
42. 1os0: Thermolysin with an Alpha-amino Phosphinic Inhibitor
43. 1pe5: Thermolysin with Tricyclic Inhibitor
44. 1pe7: Thermolysin with Bicyclic Inhibitor
45. 1pe8: Thermolysin with Monocyclic Inhibitor
46. 1qf0: Thermolysin (e.c.3.4.24.27) Complexed with (2-sulphanyl-3- Phenylpropanoyl)-phe-tyr. Parameters for Zn-bidentation of Mercaptoacyldipeptides in Metalloendopeptidase
47. 1qf1: Thermolysin (e.c.3.4.24.27) Complexed with (2- Sulphanylheptanoyl)-phe-ala. Parameters for Zn-bidentation of Mercaptoacyldipeptides in Metalloendopeptidase
48. 1qf2: Thermolysin (e.c.3.4.24.27) Complexed with (2-sulphanyl-3- Phenylpropanoyl)-gly-(5-phenylproline). Parameters for Zn- Monodentation of Mercaptoacyldipeptides in Metalloendopeptidase
49. 3fxs: Metal Exchange in Thermolysin
50. 3fxp: Thermolysin Inhibition
51. 3fvp: Thermolysin Inhibition
52. 3fv4: Thermolysin Inhibition
53. 3for: Thermolysin Complexed with Bnpa (2-benzyl-3-nitro Propanoic Acid Amide)
54. 3flf: Thermolysin Inhibition
55. 3fgd: Drugscore Fp: Thermoylsin in Complex with Fragment.
56. 3fcq: Thermolysin Inhibition
57. 3fbo: Metal Exchange in Thermolysin
58. 3fb0: Metal Exchange in Thermolysin
59. 3f2p: Thermolysin Inhibition
60. 3f28: Thermolysin Inhibition
61. 3eim: Metal Exchange in Thermolysin
62. 1thl: Thermolysin Complexed with a Novel Glutaramide Derivative, N-(1-(2(r,s)-carboxy-4-phenylbutyl) Cyclopentylcarbonyl)- (s)-tryptophan
63. 1tli: Thermolysin (2% Isopropanol Soaked Crystals)
64. 1tlp: Crystallographic Structural Analysis of Phosphoramidates as Inhibitors and Transition-state Analogs of Thermolysin
65. 1tlx: Thermolysin (native)
66. 1tmn: Binding of N-carboxymethyl Dipepetide Inhibitors to Thermolysin Determined by X-ray Crystallography. a Novel Class of Transition-state Analogues for Zinc Peptidases
67. 1trl: Nmr Solution Structure of The C-terminal Fragment 255-316 of Thermolysin: a Dimer Formed by Subunits Having The Native Structure
68. 3do2: Thermolysin by Lb Nanotemplate Method after High X-ray Dose on Esrf Id14-2 Beamline
69. 3do1: Thermolysin by Classical Hanging Drop Method before High X- Ray Dose on Esrf Id14-2 Beamline
70. 3do0: Thermolysin by Classical Hanging Drop Method after High X- Ray Dose on Esrf Id14-2 Beamline
71. 3dnz: Thermolysin by Lb Nanotemplate Method before High X-ray Dose on Esrf Id14-2 Beamline
72. 1y3g: Crystal Structure of a Silanediol Protease Inhibitor Bound to Thermolysin
73. 2wi0: Dipeptide Inhibitors of Thermolysin
74. 2whz: Dipeptide Inhibitors of Thermolysin
75. 1z9g: Crystal Structure Analysis of Thermolysin Complexed with The Inhibitor (r)-retro-thiorphan
76. 1zdp: Crystal Structure Analysis of Thermolysin Complexed with The Inhibitor (s)-thiorphan
77. 7akn: Thermolysin from Bacillus Thermoproteolyticus
78. 2tmn: Crystallographic Structural Analysis of Phosphoramidates as Inhibitors and Transition-state Analogs of Thermolysin
79. 2tlx: Thermolysin (native)
80. 2tli: Thermolysin (5% Isopropanol Soaked Crystals)
81. 2g4z: Anomalous Substructure of Thermolysin
82. 6scu: Thermolysin in Complex with Fragment J88
83. 6sck: Thermolysin in Complex with Fragment J77
84. 6sc3: Thermolysin in Complex with Fragment J62
85. 6sc1: Thermolysin in Complex with Fragment J96
86. 6sc0: Thermolysin in Complex with Fragment J22
87. 6sbk: Thermolysin in Complex with Fragment J13
88. 6sb9: Thermolysin in Complex with J28
89. 3p7p: Radiation Damage Study of Thermolysin - 100k Structure a (0.1 Mgy)
90. 3p7q: Radiation Damage Study of Thermolysin - 100k Structure B (2.5 Mgy)
91. 3p7r: Radiation Damage Study of Thermolysin - 100k Structure C (4.9 Mgy)
92. 3p7s: Radiation Damage Study of Thermolysin - 100k Structure D (7.2 Mgy)
93. 3p7t: Radiation Damage Study of Thermolysin - 160k Structure a (0.1 Mgy)
94. 3p7u: Radiation Damage Study of Thermolysin - 160k Structure B (2.4 Mgy)
95. 3p7v: Radiation Damage Study of Thermolysin - 160k Structure C (4.8 Mgy)
96. 3p7w: Radiation Damage Study of Thermolysin - 160k Structure D (7.1 Mgy)
97. 3ls7: Crystal Structure of Thermolysin in Complex with Xenon
98. 3ms3: Crystal Structure of Thermolysin in Complex with Aniline
99. 3msa: Crystal Structure of Thermolysin in Complex with 3-bromophenol
100. 3msf: Crystal Structure of Thermolysin in Complex with Urea
101. 3msn: Crystal Structure of Thermolysin in Complex with N-methylurea
102. 3n21: Crystal Structure of Thermolysin in Complex with S-1,2-propandiol
103. 3nn7: Crystal Structure of Thermolysin in Complex with 2-bromoacetate
104. 3ssb: Structure of Insect Metalloproteinase Inhibitor in Complex with Thermolysin
105. 6sel: Multicrystal Structure of Thermolysin at Room Temperature Using a Multilayer Monochromator.
106. 3t2h: Tetragonal Thermolysin in The Presence of Tmao
107. 3t2i: Tetragonal Thermolysin in The Presence of Sarcosine
108. 3t2j: Tetragonal Thermolysin in The Presence of Betaine
109. 3qgo: Structure of Thermolysin in Complex with L-phenylalanine Methylester
110. 3qh1: Structure of Thermolysin in Complex with N-benzyloxycarbonyl-l- Aspartic Acid
111. 3qh5: Structure of Thermolysin in Complex with N-carbobenzyloxy-l-aspartic Acid and L-phenylalanine Methyl Ester
112. 6qf3: X-ray Structure of Thermolysin Soaked with Sodium Aspartate on a Silicon Chip
113. 6qf2: X-ray Structure of Thermolysin Crystallized on a Silicon Chip
114. 6n4z: Tetragonal Thermolysin (with 50% Xylose) Plunge Cooled in Liquid Nitrogen to 77 K
115. 6n4w: Tetragonal Thermolysin (with 50% Xylose) Cryocooled in a Nitrogen Gas Stream to 100 K
116. 3t73: Thermolysin in Complex with Ubtln22
117. 3t74: Thermolysin in Complex with Ubtln27
118. 3t87: Thermolysin in Complex with Ubtln28
119. 3t8c: Thermolysin in Complex with Ubtln30
120. 3t8d: Thermolysin in Complex with Ubtln31
121. 3t8f: Thermolysin in Complex with Ubtln34
122. 3t8g: Thermolysin in Complex with Ubtln26
123. 3t8h: Thermolysin in Complex with Ubtln29
124. 4h57: Thermolysin Inhibition
125. 6ig7: Crystal Structure of Thermolysin Delivered in Polyacrylamide Using X- Ray Free Electron Laser
126. 4d91: Thermolysin in Complex with Dmso and Acetate
127. 4d9w: Thermolysin in Complex with Ubtln32
128. 3zi6: Structure of Thermolysin Solved by Sad from Data Collected by Direct Data Collection (ddc) Using The Grob Robot Goniometer
129. 6ghx: Alzheimer's Amyloid-beta Peptide Fragment 31-35 in Complex with Cd- Substituted Thermolysin
130. 6fsm: Crystal Structure of Tce-treated Thermolysin
131. 6fj2: Structure of Thermolysin Solved from Sad Data Collected at The Peak of The Zn Absorption Edge on ID30B
132. 6fhp: Daip in Complex with a C-terminal Fragment of Thermolysin
133. 6d5u: Hexagonal Thermolysin Cryocooled to 100 K with 50% Methanol as Cryoprotectant
134. 6d5t: Hexagonal Thermolysin Cryocooled to 100 K with 50% Mpd as Cryoprotectant
135. 6d5s: Hexagonal Thermolysin Cryocooled to 100 K with 50% Mpd as Cryoprotectant
136. 6d5r: Hexagonal Thermolysin Cryocooled to 100 K with 50% Xylose as Cryoprotectant
137. 6d5q: Hexagonal Thermolysin Cryocooled to 100 K with 30% Xylose as Cryoprotectant
138. 6d5p: Hexagonal Thermolysin Cryocooled to 100 K with 20% Xylose as Cryoprotectant
139. 6d5o: Hexagonal Thermolysin (295 K) in The Presence of 50% Dmf
140. 6d5n: Hexagonal Thermolysin (295) in The Presence of 50% Xylose
141. 4mtw: Thermolysin in Complex with Ubtln36
142. 4mwp: Thermolysin in Complex with Ubtln46
143. 4mxj: Thermolysin in Complex with Ubtln35
144. 4mzn: Thermolysin in Complex with Ubtln59
145. 4n4e: Thermolysin in Complex with Ubtln58
146. 4n5p: Thermolysin in Complex with Ubtln20
147. 4n66: Thermolysin in Complex with Ubtln37
148. 4oi5: Glycerol-free Structure of Thermolysin in Complex with Ubtln58
149. 4ow3: Thermolysin Structure Determined by Free-electron Laser
150. 5wr6: Thermolysin, Liganded Form with Cryo Condition 2
151. 5wr5: Thermolysin, Liganded Form with Cryo Condition 1
152. 5wr4: Thermolysin, Sfx Unliganded Form with Oil-based Carrier
153. 5wr3: Thermolysin, Sfx Liganded Form with Water-based Carrier
154. 5wr2: Thermolysin, Sfx Liganded Form with Oil-based Carrier
155. 4tnl: 1.8 a Resolution Room Temperature Structure of Thermolysin Recorded Using an Xfel
156. 6qar: Thermolysine under 2 Kbar of Argon
157. 5uue: Tetragonal Thermolysin Cryocooled to 100 K with 50% Methanol as Cryoprotectant
158. 5uud: Tetragonal Thermolysin Cryocooled to 100 K with 50% Dmf as Cryoprotectant
159. 5uuc: Tetragonal Thermolysin Cryocooled to 100 K with 50% Mpd as Cryoprotectant
160. 5uub: Tetragonal Thermolysin Cryocooled to 100 K with 25% Xylose/25% Mpd as Cryoprotectant
161. 5uua: Tetragonal Thermolysin Cryocooled to 100 K with 50% Xylose as Cryoprotectant
162. 5uu9: Tetragonal Thermolysin Cryocooled to 100 K with 40% Xylose as Cryoprotectant
163. 5uu8: Tetragonal Thermolysin Cryocooled to 100 K with 30% Xylose as Cryoprotectant
164. 5uu7: Tetragonal Thermolysin (295 K) in The Presence of 50% Mpd
165. 5un3: Tetragonal Thermolysin (295 K) in The Presence of 50% Xylose
166. 5tak: Conformational Sampling Differences across The Arrhenius Plot Biphasic Break Point at Ambient Temperature in The Enzyme Thermolysin
167. 5taj: Conformational Sampling Differences across The Arrhenius Plot Biphasic Break Point at Ambient Temperature in The Enzyme Thermolysin
168. 5tai: Conformational Sampling Differences across The Arrhenius Plot Biphasic Break Point at Ambient Temperature in The Enzyme Thermolysin
169. 5tae: Conformational Sampling Differences across The Arrhenius Plot Biphasic Break Point at Ambient Temperature in The Enzyme Thermolysin
170. 5tad: Conformational Sampling Differences across The Arrhenius Plot Biphasic Break Point at Ambient Temperature in The Enzyme Thermolysin
171. 5tac: Conformational Sampling Differences across The Arrhenius Plot Biphasic Break Point at Ambient Temperature in The Enzyme Thermolysin
172. 5t9q: Conformational Sampling Differences across The Arrhenius Plot Biphasic Break Point at Ambient Temperature in The Enzyme Thermolysin
173. 5t9k: Conformational Sampling Differences across The Arrhenius Plot Biphasic Break Point at Ambient Temperature in The Enzyme Thermolysin
174. 5t9i: Conformational Sampling Differences across The Arrhenius Plot Biphasic Break Point at Ambient Temperature in The Enzyme Thermolysin
175. 5onr: Alzheimer's Amyloid-beta Peptide Fragment 1-40 in Complex with Thermolysin
176. 5onq: Alzheimer's Amyloid-beta Peptide Fragment 29-40 in Complex with Cd- Substituted Thermolysin
177. 5onp: Alzheimer's Amyloid-beta Peptide Fragment 1-40 in Complex with Cd- Substituted Thermolysin
178. 5o8n: Structure of Thermolysin at Room Temperature via a Method of Acoustically Induced Rotation.
179. 5n3y: Thermolysin in Complex with Inhibitor Jc267
180. 5n3v: Thermolysin in Complex with Inhibitor Jc292
181. 5n34: Thermolysin in Complex with Inhibitor Jc276
182. 5n31: Thermolysin in Complex with Inhibitor Jc277
183. 5n2z: Thermolysin in Complex with Inhibitor Jc286
184. 5n2x: Thermolysin in Complex with Inhibitor Jc272
185. 5n2t: Thermolysin in Complex with Inhibitor Jc287
186. 5mnr: Thermolysin in Complex with Inhibitor Jc256
187. 5ma7: Structure of Thermolysin in Complex with Inhibitor (jc306).
188. 5m9w: Experimental Mad Phased Structure of Thermolysin in Complex with Inhibitor Jc65.
189. 5m69: Thermolysin in Complex with Inhibitor and Xenon
190. 5m5f: Thermolysin in Complex with Inhibitor and Krypton
191. 5lwd: Thermolysin in Complex with Inhibitor (jc96)
192. 5lvd: Thermolysin in Complex with Inhibitor (jc67)
193. 5lif: Thermolysin in Complex with Inhibitor
194. 5l8p: Thermolysin in Complex with Jc114 (peg400 Cryo Protectant)
195. 5l41: Thermolysin in Complex with Jc148 (mpd Cryo Protectant)
196. 5l3u: Thermolysin in Complex with Jc149 (mpd Cryo Protectant)
197. 5k7t: Microed Structure of Thermolysin at 2.5 a Resolution
198. 5jxn: Thermolysin in Complex with Jc240.
199. 5jvi: Thermolysin in Complex with Jc148.
200. 5jt9: Thermolysin in Complex with Jc106.
201. 5jss: Thermolysin in Complex with Jc149.
202. 5js3: Thermolysin in Complex with Jc114.
203. 5fxn: Structure of Thermolysin Solved by Sad from Data Collected by Direct Data Collection (ddc) Using The Esrf Robodiff Goniometer
204. 5fss: Structure of Thermolysin Prepared by The 'soak-and-freeze' Method under 40 Bar of Krypton Pressure
205. 5fsp: Structure of Thermolysin Prepared by The 'soak-and-freeze' Method under 100 Bar of Krypton Pressure
206. 5fsj: Structure of Thermolysin Prepared by The 'soak-and-freeze' Method under 45 Bar of Oxygen Pressure
207. 5dpf: Thermolysin in Complex with Inhibitor.
208. 5dpe: Thermolysin in Complex with Inhibitor.
209. 5dlh: Sfx Structure of Thermolysin
210. 5a3y: Sad Structure of Thermolysin Obtained by Multi Crystal Data Collection
211. 6lzn: Thermolysin
212. 6lzo: Thermolysin with 1,10-phenanthroline
213. 6zhj: 3d Electron Diffraction Structure of Thermolysin from Bacillus Thermoproteolyticus
214. 6y4i: Structural and Kinetic Evaluation of Phosphoramidate Inhibitors on Thermolysin
215. 6yi6: Structural and Kinetic Evaluation of Phosphoramidate Inhibitors on Thermolysin
216. 6ymr: Structural and Kinetic Evaluation of Phosphoramidate Inhibitors on Thermolysin
217. 6yms: Structural and Kinetic Evaluation of Phosphoramidate Inhibitors on Thermolysin