EC 3.4.24.69 - bontoxilysin

3D structures of EC 3.4.24.69 - bontoxilysin in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1e1h: Crystal Structure of Recombinant Botulinum Neurotoxin Type a Light Chain, Self-inhibiting Zn Endopeptidase.
2. 1epw: Crystal Structure of Clostridium Neurotoxin Type B
3. 1f31: Crystal Structure of Clostridium Botulinum Neurotoxin B Complexed with a Trisaccharide
4. 1f82: Botulinum Neurotoxin Type B Catalytic Domain
5. 1g9a: Crystal Structure of Clostridium Botulinum Neurotoxin B Complexed with an Inhibitor (experiment 3)
6. 1g9b: Crystal Structure of Clostridium Botulinum Neurotoxin B Complexed with an Inhibitor (experiment 1)
7. 1g9c: Crystal Structure of Clostridium Botulinum Neurotoxin B Complexed with an Inhibitor (experiment 4)
8. 1g9d: Crystal Structure of Clostridium Botulinum Neurotoxin B Complexed with an Inhibitor (experiment 2)
9. 1i1e: Crystal Structure of Clostridium Botulinum Neurotoxin B Complexed with Doxorubicin
10. 3ogg: Crystal Structure of The Receptor Binding Domain of Botulinum Neurotoxin D
11. 3obt: Crystal Structure of Botulinum Neurotoxin Serotype D Ligand Binding Domain in Complex with N-acetylneuraminic Acid
12. 3obr: Crystal Structure of Botulinum Neurotoxin Serotype D Binding Domain
13. 3mpp: Botulinum Neurotoxin Type G Receptor Binding Domain
14. 3k3q: Crystal Structure of a Llama Antibody Complexed with The C. Botulinum Neurotoxin Serotype a Catalytic Domain
15. 1s0b: Crystal Structure of Botulinum Neurotoxin Type B at Ph 4.0
16. 1s0c: Crystal Structure of Botulinum Neurotoxin Type B at Ph 5.0
17. 1s0d: Crystal Structure of Botulinum Neurotoxin Type B at Ph 5.5
18. 1s0e: Crystal Structure of Botulinum Neurotoxin Type B at Ph 6.0
19. 1s0f: Crystal Structure of Botulinum Neurotoxin Type B at Ph 7.0
20. 1s0g: Crystal Structure of Botulinum Neurotoxin Type B Apo Form
21. 3fuo: The Crystal Structure of Receptor Binding Domain of Botulinum Neurotoxin Serotype a
22. 3fii: Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Catalytic Domain with an Inhibitor (inh2)
23. 3fie: Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Catalytic Domain with an Inhibitor (inh1)
24. 3ffz: Domain Organization in Clostridium Butulinum Neurotoxin Type E Is Unique: Its Implication in Faster Translocation
25. 1t3a: Crystal Structure of Clostridium Botulinum Neurotoxin Type E Catalytic Domain
26. 1t3c: Clostridium Botulinum Type E Catalytic Domain E212Q Mutant
27. 6uc6: Crystal Structure of Bont/b Receptor-binding Domain in Complex with Vhh Jli-h11
28. 3dse: A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype a Has a Very Different Conformation than Snap-25 Substrate
29. 3ds9: A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype a Has a Very Different Conformation than Snap-25 Substrate
30. 3deb: Crystal Structure of Apo Form (zinc Removed) of The Botulinum Neurotoxin Type C Light Chain
31. 3ddb: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Serotype a with a Substrate Analog Peptide
32. 3dda: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Serotype a with a Snap-25 Peptide
33. 3c8b: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Serotype a with Inhibitory Peptide Rrgi
34. 3c8a: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Serotype a with Inhibitory Peptide Rrgl
35. 3c89: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Serotype a with Inhibitory Peptide Rrgm
36. 3c88: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Serotype a with Inhibitory Peptide Rrgc
37. 3bwi: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Serotype a with an Acetate Ion Bound at The Active Site
38. 3bta: Crystal Structure of Botulinum Neurotoxin Serotype a
39. 3boo: Structure of The C. Botulinum Neurotoxin Serotype a with an Inhibitory Peptide Bound
40. 2xhl: Structure of a Functional Derivative of Clostridium Botulinum Neurotoxin Type B
41. 1z0h: N-terminal Helix Reorients in Recombinant C-fragment of Clostridium Botulinum Type B
42. 2w2d: Crystal Structure of a Catalytically Active, Non-toxic Endopeptidase Derivative of Clostridium Botulinum Toxin a
43. 1zkw: Crystal Structure of ARG347ALA Mutant of Botulinum Neurotoxin E Catalytic Domain
44. 1zkx: Crystal Structure of GLU158ALA/THR159ALA/ASN160ALA- a Triple Mutant of Clostridium Botulinum Neurotoxin E Catalytic Domain
45. 1zl5: Crystal Structure of GLU335GLN Mutant of Clostridium Botulinum Neurotoxin E Catalytic Domain
46. 1zl6: Crystal Structure of TYR350ALA Mutant of Clostridium Botulinum Neurotoxin E Catalytic Domain
47. 1zn3: Crystal Structure of GLU335ALA Mutant of Clostridium Botulinum Neurotoxin Type E
48. 2vua: Crystal Structure of The Botulinum Neurotoxin Serotype a Binding Domain
49. 2vu9: Crystal Structure of Botulinum Neurotoxin Serotype a Binding Domain in Complex with GT1B
50. 7kz7: Crystals Structure of The Mutated Protease Domain of Botulinum Neurotoxin X (X4130B1).
51. 2a8a: Crystal Structure of Clostridium Botulinum Neurotoxin Serotype F Light Chain
52. 2a97: Crystal Structure of Catalytic Domain of Clostridium Botulinum Neurotoxin Serotype F
53. 2nz9: Crystal Structure of Botulinum Neurotoxin Type a Complexed with Monoclonal Antibody Ar2
54. 2nyy: Crystal Structure of Botulinum Neurotoxin Type a Complexed with Monoclonal Antibody Cr1
55. 2np0: Crystal Structure of The Botulinum Neurotoxin Type B Complexed with Synaptotagamin-ii Ectodomain
56. 2nm1: Structure of Bont/b in Complex with Its Protein Receptor
57. 2etf: Crystal Structure of Full Length Botulinum Neurotoxin (type B) Light Chain
58. 2fpq: Crystal Structure of Botulinum Neurotoxin Type D Light Chain
59. 2g7k: Structure of The Light Chain of Botulinum Neurotoxin, Serotype a Bound to Small Molecule Inhibitors
60. 2g7n: Structure of The Light Chain of Botulinum Neurotoxin Serotype a Bound to Small Molecule Inhibitors
61. 2g7p: Structure of The Light Chain of Botulinum Neurotoxin Serotype a Bound to Small Molecule Inhibitors
62. 2g7q: Structure of The Light Chain of Botulinum Neurotoxin Serotype a Bound to Small Molecule Inhibitors
63. 2ilp: Clostridium Botulinum Serotype a Light Chain Inhibited by 4- Chlorocinnamic Hydroxamate
64. 2ima: Clostridium Botulinum Neurotoxin Serotype a Light Chain Inhibited by 2,4-dichlorocinnamic Hydroxamate
65. 2imb: Clostridium Botulinum Neurotoxin Serotype a Light Chain Inhibited by L-arginine Hydroxamate
66. 2imc: Clostridium Botulinum Neurotoxin Serotype a Light Chain, Residues 1-424
67. 6xcf: Structure of The C. Botulinum Neurotoxin Serotype a Light Chain Protease in Complex with Noncovalent Inhibitor 59
68. 6xce: Structure of The C. Botulinum Neurotoxin Serotype a Light Chain Protease in Complex with Covalent Inhibitor 53
69. 6xcc: Structure of The C. Botulinum Neurotoxin Serotype a Light Chain Protease in Complex with Covalent Inhibitor 21
70. 6xcb: Structure of The C. Botulinum Neurotoxin Serotype a Light Chain Protease in Complex with Covalent Inhibitor 20
71. 3qix: Crystal Structure of Bont/a Lc with Zinc Bound
72. 3qiy: Crystal Structure of Bont/a Lc Complexed with Hydroxamate-based Inhibitor Pt-1
73. 3qiz: Crystal Structure of Bont/a Lc Complexed with Hydroxamate-based Inhibitor Pt-2
74. 3qj0: Crystal Structure of Bont/a Lc Complexed with Hydroxamate-based Inhibitor Pt-3
75. 3r4s: Cell Entry of Botulinum Neurotoxin Type C Is Dependent upon Interaction with Two Ganglioside Molecules
76. 3r4u: Cell Entry of Botulinum Neurotoxin Type C Is Dependent upon Interaction with Two Ganglioside Molecules
77. 6rim: Crystal Structure of The Catalytic Domain of The Weissela Oryzae Botulinum like Toxin
78. 3zuq: Crystal Structure of an Engineered Botulinum Neurotoxin Type B-derivative, Lc-b-gs-hn-b
79. 3zur: Crystal Structure of an Engineered Botulinum Neurotoxin Type A-snare23 Derivative, Lc0-a-snap25-hn-a
80. 3zus: Crystal Structure of an Engineered Botulinum Neurotoxin Type A-snare23 Derivative, Lc-a-snap23-hn-a
81. 3qw5: Crystal Structure of The Protease Domain of Botulinum Neurotoxin Serotype a with a Peptide Inhibitor Rrgf
82. 3qw6: Crystal Structure of The Protease Domain of Botulinum Neurotoxin Serotype a with a Peptide Inhibitor Rygc
83. 3qw7: Crystal Structure of The Protease Domain of Botulinum Neurotoxin Serotype a with a Peptide Inhibitor Rrfc
84. 3qw8: Crystal Structure of The Protease Domain of Botulinum Neurotoxin Serotype a with a Peptide Inhibitor Crgc
85. 6qns: Crystal Structure of The Binding Domain of Botulinum Neurotoxin Type B Mutant I1248W/V1249W in Complex with Human Synaptotagmin 1 and GD1A Receptors
86. 6mhj: Structure of Bont Mutant
87. 6ul6: Crystal Structure of Bont/a-lchn Domain in Complex with Vna Cia- D12/11/cia-b5 and Vhh Cia-h7
88. 4ej5: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Bont/a Wild-type
89. 4el4: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Bont/a C134S/C165S Double Mutant
90. 4elc: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Bont/a C134 Mutant with Mtsea Modified Cys-165
91. 4hev: Clostridium Botulinum Serotype a Light Chain Inhibited by Adamantane Hydroxamate
92. 6g5k: Crystal Structure of The Binding Domain of Botulinum Neurotoxin Type B in Complex with Human Synaptotagmin 1
93. 6g5g: Crystal Structure of an Engineered Botulinum Neurotoxin Type B Mutant E1191M/S1199Y in Complex with Human Synaptotagmin 2
94. 6g5f: Crystal Structure of an Engineered Botulinum Neurotoxin Type B Mutant E1191M/S1199Y in Complex with Human Synaptotagmin 1
95. 4iqp: Crystal Structure of HCRA-W1266A
96. 6f0o: Botulinum Neurotoxin A3 Hc Domain
97. 4kbb: Structure of Botulinum Neurotoxin B Binding Domain in Complex with Both Synaptotagmin II and GD1A
98. 6es1: Crystal Structure of The Binding Domain from Botulinum Neurotoxin A2 Bound to Extracellular Domain of Human Receptor SV2C
99. 6uht: Crystal Structure of Bont/b Receptor-binding Domain in Complex with Vhh Jli-g10
100. 6ui1: Crystal Structure of Bont/a-lchn Domain in Complex with Vhh Cia-d12, Cia-b5, and Cia-h7
101. 6dkk: Structure of Bont
102. 4jra: Crystal Structure of The Botulinum Neurotoxin a Receptor-binding Domain in Complex with The Luminal Domain of SV2C
103. 4ks6: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Bont/a C134S Mutant with Covalent Inhibitor That Modifies Cys-165 Causing Disorder in 166-174 Stretch
104. 4ktx: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Bont/a C134S Mutant with Covalent Inhibitor That Modifies Cys-165 Causing Disorder in 167-174 Stretch
105. 4kuf: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Bont/a C134 Mutant with Mtsea Modified Cys-165 Causing Stretch Disorder
106. 6uft: Crystal Structure of Bont/b Receptor-binding Domain in Complex with Vhh Jlk-g12
107. 6ul4: Crystal Structure of Bont/b Receptor-binding Domain in Complex with Vhh Jlo-g11
108. 5vmr: Receptor Binding Domain of Bont/b in Complex with Mini-protein Binder Bot.2110.4
109. 5vid: Receptor Binding Domain of Bont/b in Complex with Mini-protein Binder Bot.0671.2
110. 5vgx: Structure of The C. Botulinum Neurotoxin Serotype a with Hg Bound
111. 5vgv: Structure of The C. Botulinum Neurotoxin Serotype a with Cu Bound
112. 5v8u: Small Molecule Inhibitor Abs-143 Bound to The Botulinum Neurotoxin Serotype a Light Chain
113. 5v8r: Small Molecule Inhibitor Abs-143 Bound to The Botulinum Neurotoxin Serotype a Light Chain
114. 5v8p: Small Molecule Inhibitor Abs-143 Bound to The Botulinum Neurotoxin Serotype a Light Chain
115. 5tpc: Binding Domain of Bont/a Complexed with Ganglioside
116. 5tpb: Binding Domain of Bont/a Complexed with Ganglioside Variant
117. 5moy: Crystal Structure of The Bont/a2 Receptor-binding Domain in Complex with The Luminal Domain of Its Neuronal Receptor SV2C
118. 5mk7: Crystal Structure of The Receptor-binding Domain of Botulinum Neurotoxin A1 (crystal Form 2)
119. 5mk6: Crystal Structure of The Receptor-binding Domain of Botulinum Neurotoxin A1 (crystal Form 1)
120. 5lr0: Binding Domain of Botulinum Neurotoxin Dc in Complex with Sialylt
121. 5l21: Crystal Structure of Bont/a Receptor Binding Domain in Complex with Vhh C2
122. 5jmc: Receptor Binding Domain of Botulinum Neurotoxin a in Complex with Rat SV2C
123. 5jlv: Receptor Binding Domain of Botulinum Neurotoxin a in Complex with Human Glycosylated SV2C
124. 5bqn: Crystal Structure of The Lhn Fragment of Botulinum Neurotoxin Type D, Mutant H233Y E230Q
125. 5bqm: Crystal Structure of Sxn101959, a Clostridium Botulinum Neurotoxin Type D Derivative and Targeted Secretion Inhibitor
126. 4zkt: Crystal Structure of The Progenitor M Complex of Clostridium Botulinum Type E Neurotoxin
127. 4zjx: Crystal Structure of The Catalytic Domain of Botulinum Neurotoxin Serotype a with a Novel Cyclic Peptide Inhibitor
128. 6xcd: Structure of The C. Botulinum Neurotoxin Serotype a Light Chain Protease in Complex with Covalent Inhibitor 22
129. 7l6v: Crystal Structure of Bont/a-lc-jpu-a5-jpu-c1-jpu-h7-jpu-d12-cia-f12
130. 7lzp: Lc/a-jpu-b9-jpu-a11-jpu-g11
131. 7m1h: Crystal Structure of Lc/a-jpu-c10-jpu-d12-jpu-b8-jpu-g3-cia-f12-cia- D12
132. 7t5f: Botulinum Neurotoxin Type B Light Chain Complexed with Nanobodies Jlj- G3 and Jne-b10