EC 3.4.24.65 - macrophage elastase

3D structures of EC 3.4.24.65 - macrophage elastase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1jiz: Crystal Structure Analysis of Human Macrophage Elastase Mmp- 12
2. 1jk3: Crystal Structure of Human Mmp-12 (macrophage Elastase) at True Atomic Resolution
3. 3nx7: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with The Inhibitor N-hydroxy-2-(n-(2-hydroxyethyl)4- Methoxyphenylsulfonamido)acetamide
4. 3n2v: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with The Inhibitor N-hydroxy-2-(n-hydroxyethyl)biphenyl-4- Ylsulfonamido)acetamide
5. 3n2u: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with The Inhibitor N-hydroxy-2-(4-methoxy-n(2-(3,4,5-trihydroxy-6- (hydroxymethyl)tetrahydro-2h-pyran-2-yloxy)ethyl)phenylsulfonamido) Acetamide
6. 3lka: Catalytic Domain of Human Mmp-12 Complexed with Hydroxamic Acid and Paramethoxy-sulfonyl Amide
7. 3lk8: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with The Inhibitor Paramethoxy-sulfonyl-glycine Hydroxamate
8. 3ljg: Human Mmp12 in Complex with Non-zinc Chelating Inhibitor
9. 3lir: Human Mmp12 in Complex with Non-zinc Chelating Inhibitor
10. 3lil: Human Mmp12 in Complex with Non-zinc Chelating Inhibitor
11. 3lik: Human Mmp12 in Complex with Non-zinc Chelating Inhibitor
12. 1os2: Ternary Enzyme-product-inhibitor Complexes of Human Mmp12
13. 1os9: Binary Enzyme-product Complexes of Human Mmp12
14. 1rmz: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with The Inhibitor Nngh at 1.3 a Resolution
15. 1ros: Crystal Structure of Mmp-12 Complexed to 2-(1,3-dioxo-1,3- Dihydro-2h-isoindol-2-yl)ethyl-4-(4-ethoxy[1,1-biphenyl]-4- Yl)-4-oxobutanoic Acid
16. 3f1a: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with The Inhibitor N-(2-nitroso-2-oxoethyl) Benzenesulfonamide
17. 3f17: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with The Inhibitor N-(2-nitroso-2-oxoethyl) Biphenyl-4-sulfonamide
18. 3f16: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with The Inhibitor (r)-n-(3-hydroxy-1-nitroso-1- Oxopropan-2-yl)-4-methoxybenzenesulfonamide
19. 3f15: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with The Inhibitor (s)-n-(2,3-dihydroxypropyl)-4- Methoxy-n-(2-nitroso-2-oxoethyl)benzenesulfonamide
20. 3ehy: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with The Inhibitor (r)-2-(4- Methoxyphenylsulfonamido)propanoic Acid
21. 3ehx: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with The Inhibitor (r)-2-(biphenyl-4- Ylsulfonamido)-4-methylpentanoic Acid
22. 1utt: Crystal Structure of Mmp-12 Complexed to 2- (1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)ethyl-4- (4-ethoxy[1,1-biphenyl]-4-yl)-4-oxobutanoic Acid
23. 1utz: Crystal Structure of Mmp-12 Complexed to (2r)-3-({[4-[(pyri Din-4-yl)phenyl]-thien-2-yl}carboxamido)(phenyl)propanoic Acid
24. 3ba0: Crystal Structure of Full-length Human Mmp-12
25. 2z2d: Solution Structure of Human Macrophage Elastase (mmp-12) Catalytic Domain Complexed with a Gamma-keto Butanoic Acid Inhibitor
26. 1y93: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with Acetohydroxamic Acid at Atomic Resolution
27. 1ycm: Solution Structure of Matrix Metalloproteinase 12 (mmp12) in The Presence of N-isobutyl-n-[4- Methoxyphenylsulfonyl]glycyl Hydroxamic Acid (nngh)
28. 2woa: Mmp12 Complex with a Beta Hydroxy Carboxylic Acid
29. 2wo9: Mmp12 Complex with a Beta Hydroxy Carboxylic Acid
30. 2wo8: Mmp12 Complex with a Beta Hydroxy Carboxylic Acid
31. 1z3j: Solution Structure of Mmp12 in The Presence of N-isobutyl-n- 4-methoxyphenylsulfonyl]glycyl Hydroxamic Acid (nngh)
32. 2w0d: Does a Fast Nuclear Magnetic Resonance Spectroscopy- and X-ray Crystallography Hybrid Approach Provide Reliable Structural Information of Ligand-protein Complexes? a Case Study of Metalloproteinases.
33. 2poj: Nmr Solution Structure of The Inhibitor-free State of Macrophage Metalloelastase (mmp-12)
34. 2oxz: Human Mmp-12 in Complex with Two Peptides Pqg and Iag
35. 2oxw: Human Mmp-12 Complexed with The Peptide Iag
36. 2oxu: Uninhibited Form of Human Mmp-12
37. 2hu6: Crystal Structure of Human Mmp-12 in Complex with Acetohydroxamic Acid and a Bicyclic Inhibitor
38. 2jxy: Solution Structure of The Hemopexin-like Domain of Mmp12
39. 2k2g: Solution Structure of The Wild-type Catalytic Domain of Human Matrix Metalloproteinase 12 (mmp-12) in Complex with a Tight-binding Inhibitor
40. 2k9c: Paramagnetic Shifts in Solid-state Nmr of Proteins to Elicit Structural Information
41. 2krj: High-resolution Solid-state Nmr Structure of a 17.6 Kda Protein
42. 6rly: Human Mmp12 (catalytic Domain) in Complex with Ap316
43. 3ts4: Human Mmp12 in Complex with L-glutamate Motif Inhibitor
44. 3tsk: Human Mmp12 in Complex with L-glutamate Motif Inhibitor
45. 4efs: Human Mmp12 in Complex with L-glutamate Motif Inhibitor
46. 3rts: Human Mmp-12 Catalytic Domain in Complex With*n*-hydroxy-2-(2- Phenylethylsulfonamido)acetamide
47. 3rtt: Human Mmp-12 Catalytic Domain in Complex With*(r)-n*-hydroxy-1- (phenethylsulfonyl)pyrrolidine-2-carboxamide
48. 4guy: Human Mmp12 Catalytic Domain in Complex With*n*-hydroxy-2-(2-(4- Methoxyphenyl)ethylsulfonamido)acetamide
49. 3uvc: Mmp12 in a Complex with The Dimeric Adduct: 5-(5-phenylhydantoin)-5- Phenylhydantoin
50. 4gql: Crystal Structure of The Catalytic Domain of Human Mmp12 in Complex with Selective Phosphinic Inhibitor Rxp470.1
51. 4gr0: Crystal Structure of The Catalytic Domain of Human Mmp12 in Complex with Selective Phosphinic Inhibitor RXP470B
52. 4gr3: Crystal Structure of The Catalytic Domain of Human Mmp12 in Complex with Selective Phosphinic Inhibitor RXP470A
53. 4gr8: Crystal Structure of The Catalytic Domain of Human Mmp12 in Complex with Selective Phosphinic Inhibitor RXP470C
54. 4h30: Crystal Structure of The Catalytic Domain of Mmp-12 in Complex with a Twin Inhibitor.
55. 4h49: Crystal Structure of The Catalytic Domain of Mmp-12 in Complex with a Twin Inhibitor.
56. 4h76: Crystal Structure of The Catalytic Domain of Human Mmp12 in Complex with a Broad Spectrum Hydroxamate Inhibitor
57. 4h84: Crystal Structure of The Catalytic Domain of Human Mmp12 in Complex with a Selective Carboxylate Based Inhibitor.
58. 4i03: Human Mmp12 in Complex with a Peg-linked Bifunctional L-glutamate Motif Inhibitor
59. 4ijo: Unraveling Hidden Allosteric Regulatory Sites in Structurally Homologues Metalloproteases
60. 6eox: Crystal Structure of Mmp12 in Complex with Carboxylic Inhibitor Lp165.
61. 6enm: Crystal Structure of Mmp12 in Complex with Hydroxamate Inhibitor Lp168.
62. 6ela: Crystal Structure of Mmp12 in Complex with Inhibitor Be4.
63. 6ekn: Crystal Structure of Mmp12 in Complex with Inhibitor Be7.
64. 6rd0: Human Mmp12 Catalytic Domain in Complex with Ap280
65. 2mlr: Membrane Bilayer Complex with Matrix Metalloproteinase-12 at Its Alpha-face
66. 2mls: Membrane Bilayer Complex with Matrix Metalloproteinase-12 at Its Beta- Face
67. 5n5k: Human Catalytic Mmp-12 in Complex with 5-(1,2-dithiolan-3-yl)-n-(3- Hydroxypropyl)pentanamide
68. 5n5j: Human Mmp12 in Complex with 3-(5-(1,2-dithiolan-3-yl)pentanamido) Propane-1-sulfonate
69. 5lab: Crystal Structure of The Catalytic Domain of Human Mmp12 Complexed with The Inhibitor Nngh
70. 5l7f: Crystal Structure of Mmp12 Mutant K421A in Complex with Rxp470.1 Conjugated with Fluorophore Cy5,5 in Space Group P21.
71. 5l79: Crystal Structure of Mmp12 in Complex with Rxp470.1 Conjugated with Fluorophore Cy5,5 in Space Group P21212.
72. 5i4o: Crystal Structure of The Catalytic Domain of Mmp-12 in Complex with a Selective Sugar-conjugated Triazole-linked Carboxylate Zinc-chelator Water-soluble Inhibitor (dc28).
73. 5i43: Crystal Structure of The Catalytic Domain of Mmp-12 in Complex with a Selective Sugar-conjugated Triazole-linked Carboxylate Chelator Water-soluble Inhibitor (dc32).
74. 5i3m: Crystal Structure of The Catalytic Domain of Mmp-12 in Complex with a Selective Sugar-conjugated Thiourea-linked Carboxylate Zinc-chelator Water-soluble Inhibitor (dc31).
75. 5i2z: Crystal Structure of The Catalytic Domain of Mmp-12 in Complex with a Selective Sugar-conjugated Triazole-linked Carboxylate Chelating Water-soluble Inhibitor (dc24).
76. 5i0l: Crystal Structure of The Catalytic Domain of Mmp-12 in Complex with a Selective Sugar-conjugated Arylsulfonamide Carboxylate Water-soluble Inhibitor (dc27).
77. 5d3c: Crystal Structure of a Double Mutant Catalytic Domain of Human Mmp12 in Complex with an Hydroxamate Analogue of Rxp470
78. 5d2b: Crystal Structure of a Mutated Catalytic Domain of Human Mmp12 in Complex with an Hydroxamate Analogue of Rxp470
79. 5czm: Crystal Structure of a Mutated Catalytic Domain of Human Mmp12 in Complex with Rxp470
80. 5cxa: Crystal Structure of The Catalytic Domain of Human Mmp12 in Complex with a Carboxylate Inhibitor Related to Rxp470
81. 2n8r: Productive Complex between Mmp-12 and Synthetic Triple-helical Collagen, Revealed through Paramagnetic Nmr
82. 7ovy: Crystal Structure of a Dimeric Based Inhibitor Jg34 in Complex with The Mmp-12 Catalytic Domain