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enzyme (lysozyme)

 
Enzymes
  Enzyme classes:
  EC 1: Oxidoreductases
  EC 2: Transferases
  EC 3: Hydrolases
    EC 3.1
    EC 3.2
    EC 3.3
    EC 3.4
    EC 3.5
      EC 3.5.1
        EC 3.5.1.1
        EC 3.5.1.2
        EC 3.5.1.3
        EC 3.5.1.4
        EC 3.5.1.5
        EC 3.5.1.6
        EC 3.5.1.7
        EC 3.5.1.8
        EC 3.5.1.9
        EC 3.5.1.10
        EC 3.5.1.11
        EC 3.5.1.12
        EC 3.5.1.13
        EC 3.5.1.14
        EC 3.5.1.15
        EC 3.5.1.16
        EC 3.5.1.17
        EC 3.5.1.18
        EC 3.5.1.19
        EC 3.5.1.20
        EC 3.5.1.21
        EC 3.5.1.22
        EC 3.5.1.23
        EC 3.5.1.24
        EC 3.5.1.25
        EC 3.5.1.26
        EC 3.5.1.27
        EC 3.5.1.28
        EC 3.5.1.29
        EC 3.5.1.30
        EC 3.5.1.31
        EC 3.5.1.32
        EC 3.5.1.33
        EC 3.5.1.34
        EC 3.5.1.35
        EC 3.5.1.36
        EC 3.5.1.37
        EC 3.5.1.39
        EC 3.5.1.40
        EC 3.5.1.41
        EC 3.5.1.42
        EC 3.5.1.43
        EC 3.5.1.44
        EC 3.5.1.45
        EC 3.5.1.46
        EC 3.5.1.47
        EC 3.5.1.48
        EC 3.5.1.49
        EC 3.5.1.50
        EC 3.5.1.51
        EC 3.5.1.52
        EC 3.5.1.53
        EC 3.5.1.54
        EC 3.5.1.55
        EC 3.5.1.56
        EC 3.5.1.57
        EC 3.5.1.58
        EC 3.5.1.59
        EC 3.5.1.60
        EC 3.5.1.61
        EC 3.5.1.62
        EC 3.5.1.63
        EC 3.5.1.64
        EC 3.5.1.65
        EC 3.5.1.66
        EC 3.5.1.67
        EC 3.5.1.68
        EC 3.5.1.69
        EC 3.5.1.70
        EC 3.5.1.71
        EC 3.5.1.72
        EC 3.5.1.73
        EC 3.5.1.74
        EC 3.5.1.75
        EC 3.5.1.76
        EC 3.5.1.77
        EC 3.5.1.78
        EC 3.5.1.79
        EC 3.5.1.80
        EC 3.5.1.81
        EC 3.5.1.82
        EC 3.5.1.83
        EC 3.5.1.84
        EC 3.5.1.85
        EC 3.5.1.86
        EC 3.5.1.87
        EC 3.5.1.88
        EC 3.5.1.89
        EC 3.5.1.90
        EC 3.5.1.91
        EC 3.5.1.92
        EC 3.5.1.93
        EC 3.5.1.94
        EC 3.5.1.95
        EC 3.5.1.96
        EC 3.5.1.97
        EC 3.5.1.98
      EC 3.5.2
      EC 3.5.3
      EC 3.5.4
      EC 3.5.5
      EC 3.5.99
    EC 3.6
    EC 3.7
    EC 3.8
    EC 3.9
    EC 3.10
    EC 3.11
    EC 3.12
    EC 3.13
  EC 4: Lyases
  EC 5: Isomerases
  EC 6: Ligases
  General information:
  Catalytic mechanism
  Enzyme kinetics
  Inhibitors
  Enzymes in industry

EC 3.5.1.98 - histone amidohydrolase (histone deacetylase)



3D structures of EC 3.5.1.98 - histone deacetylase in Protein Data Bank

updated: 29 October 2020, 11:13

In total: 121 PDB structures of EC 3.5.1.98 - histone deacetylase:
  1. 6pzr: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Resminostat
  2. 6pzo: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Yx-153
  3. 3mz7: Crystal Structure of D101L Co2+ Hdac8 Complexed with M344
  4. 3mz6: Crystal Structure of D101L Fe2+ Hdac8 Complexed with M344
  5. 3mz4: Crystal Structure of D101L Mn2+ Hdac8 Complexed with M344
  6. 3mz3: Crystal Structure of Co2+ Hdac8 Complexed with M344
  7. 3max: Crystal Structure of Human Hdac2 Complexed with an N-(2-aminophenyl) Benzamide
  8. 3gv4: Crystal Structure of Human Hdac6 Zinc Finger Domain and Ubiquitin C-terminal Peptide Rlrgg
  9. 3f0r: Crystal Structure Analysis of Human Hdac8 Complexed with Trichostatin a in a New Monoclinic Crystal Form
  10. 3f07: Crystal Structure Analysis of Human Hdac8 Complexed with Apha in a New Monoclinic Crystal Form
  11. 3f06: Crystal Structure Analysis of Human Hdac8 D101A Variant.
  12. 3ezt: Crystal Structure Analysis of Human Hdac8 D101E Variant
  13. 3ezp: Crystal Structure Analysis of Human Hdac8 D101N Variant
  14. 3ewf: Crystal Structure Analysis of Human Hdac8 H143A Variant Complexed with Substrate.
  15. 3ew8: Crystal Structure Analysis of Human Hdac8 D101L Variant
  16. 2vqw: Structure of Inhibitor-free Hdac4 Catalytic Domain (with Gain-of-function Mutation HIS332TYR)
  17. 3phd: Crystal Structure of Human Hdac6 in Complex with Ubiquitin
  18. 3sff: Crystal Structure of Human Hdac8 Inhibitor Complex, an Amino Acid Derived Inhibitor
  19. 3sfh: Crystal Structure of Human Hdac8 Inhibitor Complex, an Amino Acid Derived Inhibitor
  20. 3rqd: Ideal Thiolate-zinc Coordination Geometry in Depsipeptide Binding to Histone Deacetylase 8
  21. 4a69: Structure of Hdac3 Bound to Corepressor and Inositol Tetraphosphate
  22. 3uzd: Crystal Structure of 14-3-3 Gamma
  23. 3v31: Crystal Structure of The Peptide Bound Complex of The Ankyrin Repeat Domains of Human Ankra2
  24. 3uxg: Crystal Structure of Rfxank
  25. 3znr: Hdac7 Bound with Inhibitor Tmp269
  26. 3zns: Hdac7 Bound with Tfmo Inhibitor Tmp942
  27. 6j6t: Crystal Structure of Hda15 Hd Domain
  28. 4bkx: The Structure of Hdac1 in Complex with The Dimeric Elm2-sant Domain of Mta1 from The Nurd Complex
  29. 4cbt: Design, Synthesis, and Biological Evaluation of Potent and Selective Class Iia Hdac Inhibitors as a Potential Therapy for Huntingtons Disease
  30. 4cby: Design, Synthesis, and Biological Evaluation of Potent and Selective Class Iia Hdac Inhibitors as a Potential Therapy for Huntingtons Disease
  31. 4lxz: Structure of Human Hdac2 in Complex with Saha (vorinostat)
  32. 4ly1: Structure of Human Hdac2 in Complex with Inhibitor 4-(acetylamino)-n- [2-amino-5-(thiophen-2-yl)phenyl]benzamide
  33. 4qa0: Crystal Structure of C153F Hdac8 in Complex with Saha
  34. 4qa1: Crystal Structure of A188T Hdac8 in Complex with M344
  35. 4qa2: Crystal Structure of I243N Hdac8 in Complex with Saha
  36. 4qa3: Crystal Structure of T311M Hdac8 in Complex with Trichostatin a (tsa)
  37. 4qa4: Crystal Structure of H334R Hdac8 in Complex with M344
  38. 4qa5: Crystal Structure of A188T/Y306F Hdac8 in Complex with a Tetrapeptide Substrate
  39. 4qa6: Crystal Structure of I243N/Y306F Hdac8 in Complex with a Tetrapeptide Substrate
  40. 4qa7: Crystal Structure of H334R/Y306F Hdac8 in Complex with a Tetrapeptide Substrate
  41. 4rn0: Crystal Structure of S39D Hdac8 in Complex with a Largazole Analogue.
  42. 4rn1: Crystal Structure of S39D Hdac8 in Complex with a Largazole Analogue.
  43. 4rn2: Crystal Structure of S39D Hdac8 in Complex with a Largazole Analogue.
  44. 5a2s: Potent, Selective and Cns-penetrant Tetrasubstituted Cyclopropane Class Iia Histone Deacetylase (hdac) Inhibitors
  45. 5b8d: Crystal Structure of a Low Occupancy Fragment Candidate (n-(4-methyl- 1,3-thiazol-2-yl)propanamide) Bound Adjacent to The Ubiquitin Binding Pocket of The Hdac6 Zinc-finger Domain
  46. 5bwz: Crystal Structure of S39E Hdac8 in Complex with Droxinostat
  47. 5d1b: Crystal Structure of G117E Hdac8 in Complex with Tsa
  48. 5d1c: Crystal Structure of D233G-Y306F Hdac8 in Complex with a Tetrapeptide Substrate
  49. 5d1d: Crystal Structure of P91L-Y306F Hdac8 in Complex with a Tetrapeptide Substrate
  50. 5dc5: Crystal Structure of D176N Hdac8 in Complex with M344
  51. 5dc6: Crystal Structure of D176N-Y306F Hdac8 in Complex with a Tetrapeptide Substrate
  52. 5dc7: Crystal Structure of D176A-Y306F Hdac8 in Complex with a Tetrapeptide Substrate
  53. 5dc8: Crystal Structure of H142A-Y306F Hdac8 in Complex with a Tetrapeptide Substrate
  54. 5edu: Crystal Structure of Human Histone Deacetylase 6 Catalytic Domain 2 in Complex with Trichostatin a
  55. 5eei: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 in Complex with Saha
  56. 5eek: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 in Complex with Trichostatin a
  57. 5eem: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2
  58. 5een: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 in Complex with Belinostat
  59. 5ef7: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 in Complex with Hpob
  60. 5ef8: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 in Complex with Panobinostat
  61. 5efb: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 in Complex with Oxamflatin
  62. 5efg: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 in Complex with Acetate
  63. 5efh: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 in Complex with Trifluoroketone Transition State Analogue
  64. 5efj: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 in Complex with Hc Toxin
  65. 5efk: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 (Y745F Mutant) in Complex with Alpha Tubulin K40 Tripeptide Substrate
  66. 5efn: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 (H574A) in Complex with Histone H4 Lys6 Tripeptide Substrate
  67. 5fcw: Hdac8 Complexed with a Hydroxamic Acid
  68. 5icn: Hdac1:mta1 in Complex with Inositol-6-phosphate and a Novel Peptide Inhibitor Based on Histone H4
  69. 5ikk: Structure of The Histone Deacetylase Clr3
  70. 5iwg: Hdac2 with Ligand Brd4884
  71. 5ix0: Hdac2 with Ligand Brd7232
  72. 5j8j: A Histone Deacetylase from Saccharomyces Cerevisiae
  73. 5kh3: Crystal Structure of Fragment (3-(5-chloro-1,3-benzothiazol-2-yl) Propanoic Acid) Bound in The Ubiquitin Binding Pocket of The Hdac6 Zinc-finger Domain
  74. 5kh7: Crystal Structure of Fragment (3-[6-oxo-3-(3-pyridinyl)-1(6h)- Pyridazinyl]propanoic Acid) Bound in The Ubiquitin Binding Pocket of The Hdac6 Zinc-finger Domain
  75. 5kh9: Crystal Structure of a Low Occupancy Fragment Candidate (5-[(4- Isopropylphenyl)amino]-6-methyl-1,2,4-triazin-3(2h)-one) Bound in The Ubiquitin Binding Pocket of The Hdac6 Zinc-finger Domain
  76. 5ths: Crystal Structure of G302A Hdac8 in Complex with M344
  77. 5tht: Crystal Structure of G303A Hdac8 in Complex with M344
  78. 5thu: Crystal Structure of G304A Hdac8 in Complex with M344
  79. 5thv: Crystal Structure of G305A Hdac8 in Complex with M344
  80. 5vi6: Crystal Structure of Histone Deacetylase 8 in Complex with Trapoxin a
  81. 5wbn: Crystal Structure of Fragment 3-(3-benzyl-2-oxo-2h-[1,2,4]triazino[2, 3-c]quinazolin-6-yl)propanoic Acid Bound in The Ubiquitin Binding Pocket of The Hdac6 Zinc-finger Domain
  82. 5wpb: Crystal Structure of Fragment 3-(3-(pyridin-2-ylmethoxy)quinoxalin-2- Yl)propanoic Acid Bound in The Ubiquitin Binding Pocket of The Hdac6 Zinc-finger Domain
  83. 5zoo: Crystal Structure of Histone Deacetylase 4 (hdac4) in Complex with a Smrt Corepressor Sp1 Fragment
  84. 5zop: Crystal Structure of Histone Deacetylase 4 (hdac4) in Complex with a Smrt Corepressor Sp2 Fragment
  85. 6ce6: Structure of Hdac6 Zinc-finger Ubiquitin Binding Domain Soaked with 3, 3'-(benzo[1,2-d:5,4-d']bis(thiazole)-2,6-diyl)dipropionic Acid
  86. 6ce8: Crystal Structure of Fragment 2-(benzo[d]thiazol-2-yl)acetic Acid Bound in The Ubiquitin Binding Pocket of The Hdac6 Zinc-finger Domain
  87. 6cea: Crystal Structure of Fragment 3-(quinolin-2-yl)propanoic Acid Bound in The Ubiquitin Binding Pocket of The Hdac6 Zinc-finger Domain
  88. 6cec: Crystal Structure of Fragment 3-(3-methoxy-2-quinoxalinyl)propanoic Acid Bound in The Ubiquitin Binding Pocket of The Hdac6 Zinc-finger Domain
  89. 6ced: Crystal Structure of Fragment 3-(3-methyl-4-oxo-3,4-dihydroquinazolin- 2-yl)propanoic Acid Bound in The Ubiquitin Binding Pocket of The Hdac6 Zinc-finger Domain
  90. 6cee: Crystal Structure of Fragment 3-(1-methyl-2-oxo-1,2-dihydroquinoxalin- 3-yl)propionic Acid Bound in The Ubiquitin Binding Pocket of The Hdac6 Zinc-finger Domain
  91. 6cef: Crystal Structure of Fragment 3-(1,3-benzothiazol-2-yl)propanoic Acid Bound in The Ubiquitin Binding Pocket of The Hdac6 Zinc-finger Domain
  92. 6fu1: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with a N- Alkyl Hydroxamate
  93. 6fyz: Development and Characterization of a Cns-penetrant Benzhydryl Hydroxamic Acid Class Iia Histone Deacetylase Inhibitor
  94. 6g3o: Crystal Structure of Human Hdac2 in Complex with (r)-6-[3,4-dioxo-2- (4-trifluoromethoxy-phenylamino)-cyclobut-1-enylamino]-heptanoic Acid Hydroxyamide
  95. 6gx3: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with an Hydroxamate 1
  96. 6gxa: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with an Hydroxamate 2
  97. 6gxu: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with an Hydroxamate 3
  98. 6gxw: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with an Hydroxamate 4
  99. 6hqy: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with Pci- 34051
  100. 6hrq: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with Ncc-149
  101. 6hsf: Crystal Structure of Schistosoma Mansoni Hdac8 Mutant H292M Complexed with Pci-34051
  102. 6hsg: Crystal Structure of Schistosoma Mansoni Hdac8 H292M Mutant Complexed with Ncc-149
  103. 6hsh: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with Quisinostat
  104. 6hsk: Crystal Structure of a Human Hdac8 L6 Loop Mutant Complexed with Quisinostat
  105. 6hsz: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with a Benzohydroxamate Inhibitor 2
  106. 6ht8: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with a Benzohydroxamate Inhibitor 3
  107. 6htg: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with a Benzohydroxamate Inhibitor 4
  108. 6hth: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with a Benzohydroxamate Inhibitor 5
  109. 6hti: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with a Benzohydroxamate Inhibitor 6
  110. 6htt: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with a Benzohydroxamate Inhibitor 7
  111. 6htz: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with a Benzohydroxamate Inhibitor 8
  112. 6hu0: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with a Benzohydroxamate Inhibitor 9
  113. 6hu1: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with a Benzohydroxamate Inhibitor 10
  114. 6hu2: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with a Benzohydroxamate Inhibitor 11
  115. 6hu3: Crystal Structure of Schistosoma Mansoni Hdac8 Complexed with a Triazole Hydroxamate Inhibitor
  116. 6pzs: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Jr005
  117. 6oda: Crystal Structure of Hdac8 in Complex with Compound 2
  118. 6odb: Crystal Structure of Hdac8 in Complex with Compound 3
  119. 6odc: Crystal Structure of Hdac8 in Complex with Compound 30
  120. 6wbw: Structure of Human Hdac2 in Complex with an Ethyl Ketone Inhibitor
  121. 6wbz: Structure of Human Hdac2 in Complex with an Ethyl Ketone Inhibitor Containing a Spiro-bicyclic Group
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