Enzyme classes: General information:
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EC 2.7.1.37 - obsolete, now divided into EC 2.7.11.1, EC 2.7.11.8, EC 2.7.11.9, EC 2.7.11.10, EC 2.7.11.11, EC 2.7.11.12, EC 2.7.11.13, EC 2.7.11.21, EC 2.7.11.22, EC 2.7.11.24, EC 2.7.11.25, EC 2.7.11.30 and EC 2.7.12.1
3D structures of EC 2.7.1.37 in Protein Data Bank
updated: 6 January 2022, 2:15
In total: 413 PDB structures of EC 2.7.1.37:
- 1apm: 2.0 Angstrom Refined Crystal Structure of The Catalytic Subunit of Camp-dependent Protein Kinase Complexed with a Peptide Inhibitor and Detergent
- 1aq1: Human Cyclin Dependent Kinase 2 Complexed with The Inhibitor Staurosporine
- 1atp: 2.2 Angstrom Refined Crystal Structure of The Catalytic Subunit of Camp-dependent Protein Kinase Complexed with Mnatp and a Peptide Inhibitor
- 1b38: Human Cyclin-dependent Kinase 2
- 1b39: Human Cyclin-dependent Kinase 2 Phosphorylated on Thr 160
- 1b6c: Crystal Structure of The Cytoplasmic Domain of The Type I Tgf-beta Receptor in Complex with Fkbp12
- 1bdy: C2 Domain from Protein Kinase C Delta
- 1bkx: A Binary Complex of The Catalytic Subunit of Camp-dependent Protein Kinase and Adenosine Further Defines Conformational Flexibility
- 1bx6: Crystal Structure of The Potent Natural Product Inhibitor Balanol in Complex with The Catalytic Subunit of Camp- Dependent Protein Kinase
- 1ckp: Human Cyclin Dependent Kinase 2 Complexed with The Inhibitor Purvalanol B
- 1ctp: Structure of The Mammalian Catalytic Subunit of Camp- Dependent Protein Kinase and an Inhibitor Peptide Displays an Open Conformation
- 1daw: Crystal Structure of a Binary Complex of Protein Kinase Ck2 (alpha-subunit) and Mg-amppnp
- 1day: Crystal Structure of a Binary Complex of Protein Kinase Ck2 (alpha-subunit) and Mg-gmppnp
- 1ddm: Solution Structure of The Numb Ptb Domain Complexed to a Nak Peptide
- 1ds5: Dimeric Crystal Structure of The Alpha Subunit in Complex with Two Beta Peptides Mimicking The Architecture of The Tetrameric Protein Kinase Ck2 Holoenzyme.
- 1e1v: Human Cyclin Dependent Kinase 2 Complexed with The Inhibitor Nu2058
- 1e1x: Human Cyclin Dependent Kinase 2 Complexed with The Inhibitor Nu6027
- 1e9h: Thr 160 Phosphorylated Cdk2 - Human Cyclin A3 Complex with The Inhibitor Indirubin-5-sulphonate Bound
- 1f0q: Crystal Structure of The Alpha Subunit of Protein Kinase Ck2 in Complex with The Nucleotide Competitive Inhibitor Emodin
- 1fmo: Crystal Structure of a Polyhistidine-tagged Recombinant Catalytic Subunit of Camp-dependent Protein Kinase Complexed with The Peptide Inhibitor Pki(5-24) and Adenosine
- 1fot: Structure of The Unliganded Camp-dependent Protein Kinase Catalytic Subunit from Saccharomyces Cerevisiae
- 1fvt: The Structure of Cyclin-dependent Kinase 2 (cdk2) in Complex with an Oxindole Inhibitor
- 1fvv: The Structure of Cdk2/cyclin a in Complex with an Oxindole Inhibitor
- 1g3n: Structure of a P18(INK4C)-CDK6-K-CYCLIN Ternary Complex
- 1gih: Human Cyclin Dependent Kinase 2 Complexed with The Cdk4 Inhibitor
- 1gii: Human Cyclin Dependent Kinase 2 Complexed with The Cdk4 Inhibitor
- 1gij: Human Cyclin Dependent Kinase 2 Complexed with The Cdk4 Inhibitor
- 1gng: Glycogen Synthase Kinase-3 Beta (gsk3) Complex with Frattide Peptide
- 1gz8: Human Cyclin Dependent Kinase 2 Complexed with The Inhibitor 2-amino-6-(3'-methyl-2'-oxo)butoxypurine
- 1h00: Cdk2 in Complex with a Disubstituted 4, 6-bis Anilino Pyrimidine Cdk4 Inhibitor
- 1h07: Cdk2 in Complex with a Disubstituted 4, 6-bis Anilino Pyrimidine Cdk4 Inhibitor
- 1h08: Cdk2 in Complex with a Disubstituted 2, 4-bis Anilino Pyrimidine Cdk4 Inhibitor
- 1h0v: Human Cyclin Dependent Protein Kinase 2 in Complex with The Inhibitor 2-amino-6-[(r)-pyrrolidino-5'-yl]methoxypurine
- 1h0w: Human Cyclin Dependent Protein Kinase 2 in Complex with The Inhibitor 2-amino-6-[cyclohex-3-enyl]methoxypurine
- 1h8f: Glycogen Synthase Kinase 3 Beta.
- 1hck: Human Cyclin-dependent Kinase 2
- 1hcl: Human Cyclin-dependent Kinase 2
- 1i09: Structure of Glycogen Synthase Kinase-3 (GSK3B)
- 1ia9: Crystal Structure of The Atypical Protein Kinase Domain of a Trp Ca-channel, Chak (amppnp Complex)
- 1iah: Crystal Structure of The Atypical Protein Kinase Domain of a Trp Ca-channel, Chak (adp-mg Complex)
- 1iaj: Crystal Structure of The Atypical Protein Kinase Domain of a Trp Ca-channel, Chak (apo)
- 1ias: Cytoplasmic Domain of Unphosphorylated Type I Tgf-beta Receptor Crystallized without Fkbp12
- 1id0: Crystal Structure of The Nucleotide Bond Conformation of Phoq Kinase Domain
- 1ik7: Crystal Structure of The Uncomplexed Pelle Death Domain
- 1j1b: Binary Complex Structure of Human Tau Protein Kinase I with Amppnp
- 1j1c: Binary Complex Structure of Human Tau Protein Kinase I with Adp
- 1j3h: Crystal Structure of Apoenzyme Camp-dependent Protein Kinase Catalytic Subunit
- 1j91: Crystal Structure of Z. Mays Ck2 Kinase Alpha Subunit in Complex with The Atp-competitive Inhibitor 4,5,6,7- Tetrabromobenzotriazole
- 1jam: Crystal Structure of Apo-form of Z. Mays Ck2 Protein Kinase Alpha Subunit
- 1jbp: Crystal Structure of The Catalytic Subunit of Camp- Dependent Protein Kinase Complexed with a Substrate Peptide, Adp and Detergent
- 1jlu: Crystal Structure of The Catalytic Subunit of Camp- Dependent Protein Kinase Complexed with a Phosphorylated Substrate Peptide and Detergent
- 1jvp: Crystal Structure of Human Cdk2 (unphosphorylated) in Complex with Pkf049-365
- 1jwh: Crystal Structure of Human Protein Kinase Ck2 Holoenzyme
- 1ke5: Cdk2 Complexed with N-methyl-4-{[(2-oxo-1,2-dihydro-3h- Indol-3-ylidene)methyl]amino}benzenesulfonamide
- 1ke6: Cyclin-dependent Kinase 2 (cdk2) Complexed with N-methyl-{4- [2-(7-oxo-6,7-dihydro-8h-[1,3]thiazolo[5,4-e]indol-8- Ylidene)hydrazino]phenyl}methanesulfonamide
- 1ke7: Cyclin-dependent Kinase 2 (cdk2) Complexed with 3-{[(2,2- Dioxido-1,3-dihydro-2-benzothien-5-yl)amino]methylene}-5- (1,3-oxazol-5-yl)-1,3-dihydro-2h-indol-2-one
- 1ke8: Cyclin-dependent Kinase 2 (cdk2) Complexed with 4-{[(2-oxo- 1,2-dihydro-3h-indol-3-ylidene)methyl]amino}-n-(1,3- Thiazol-2-yl)benzenesulfonamide
- 1ke9: Cyclin-dependent Kinase 2 (cdk2) Complexed with 3-{[4- ({[amino(imino)methyl]aminosulfonyl)anilino]methylene}-2- Oxo-2,3-dihydro-1h-indole
- 1ktz: Crystal Structure of The Human Tgf-beta Type II Receptor Extracellular Domain in Complex with Tgf-beta3
- 1l3r: Crystal Structure of a Transition State Mimic of The Catalytic Subunit of Camp-dependent Protein Kinase
- 1l6e: Solution Structure of The Docking and Dimerization Domain of Protein Kinase a Ii-alpha (riialpha D/d). Alternatively Called The N-terminal Dimerization Domain of The Regulatory Subunit of Protein Kinase A.
- 1ll8: Structure and Interactions of Pas Kinase N-terminal Pas Domain: Model for Intramolecular Kinase Regulation
- 1lp4: Crystal Structure of a Binary Complex of The Catalytic Subunit of Protein Kinase Ck2 with Mg-amppnp
- 1lpu: Low Temperature Crystal Structure of The Apo-form of The Catalytic Subunit of Protein Kinase Ck2 from Zea Mays
- 1lr4: Room Temperature Crystal Structure of The Apo-form of The Catalytic Subunit of Protein Kinase Ck2 from Zea Mays
- 1m2p: Crystal Structure of 1,8-di-hydroxy-4-nitro- Anthraquinone/ck2 Kinase Complex
- 1m2q: Crystal Structure of 1,8-di-hydroxy-4-nitro-xanten-9- One/ck2 Kinase Complex
- 1m2r: Crystal Structure of 5,8-di-amino-1,4-di-hydroxy- Anthraquinone/ck2 Kinase Complex
- 1mby: Murine Sak Polo Domain
- 1na7: Crystal Structure of The Catalytic Subunit of Human Protein Kinase Ck2
- 1o6k: Structure of Activated Form of Pkb Kinase Domain S474D with Gsk3 Peptide and Amp-pnp
- 1o6l: Crystal Structure of an Activated Akt/protein Kinase B (pkb-pif Chimera) Ternary Complex with Amp-pnp and Gsk3 Peptide
- 1o9u: Glycogen Synthase Kinase 3 Beta Complexed with Axin Peptide
- 1ogu: Structure of Human Thr160-phospho Cdk2/cyclin a Complexed with a 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine Inhibitor
- 1oi9: Structure of Human Thr160-phospho Cdk2/cyclin a Complexed with a 6-cyclohexylmethyloxy-2-anilino-purine Inhibitor
- 1oiq: Imidazopyridines: a Potent and Selective Class of Cyclin-dependent Kinase Inhibitors Identified through Structure-based Hybridisation
- 1oir: Imidazopyridines: a Potent and Selective Class of Cyclin-dependent Kinase Inhibitors Identified through Structure-based Hybridisation
- 1oit: Imidazopyridines: a Potent and Selective Class of Cyclin-dependent Kinase Inhibitors Identified through Structure-based Hybridisation
- 1oiu: Structure of Human Thr160-phospho Cdk2/cyclin a Complexed with a 6-cyclohexylmethyloxy-2-anilino-purine Inhibitor
- 1oiy: Structure of Human Thr160-phospho Cdk2/cyclin a Complexed with a 6-cyclohexylmethyloxy-2-anilino-purine Inhibitor
- 1okv: Cyclin a Binding Groove Inhibitor H-arg-arg-leu-ile-phe-nh2
- 1okw: Cyclin a Binding Groove Inhibitor Ac-arg-arg-leu-asn- (m-cl-phe)-nh2
- 1oky: Structure of Human Pdk1 Kinase Domain in Complex with Staurosporine
- 1okz: Structure of Human Pdk1 Kinase Domain in Complex with Ucn-01
- 1ol1: Cyclin a Binding Groove Inhibitor H-cit-cit-leu-ile- (p-f-phe)-nh2
- 1ol2: Cyclin a Binding Groove Inhibitor H-arg-arg-leu-asn- (p-f-phe)-nh2
- 1ol5: Structure of Aurora-a 122-403, Phosphorylated on Thr287, Thr288 and Bound to Tpx2 1-43
- 1ol6: Structure of Unphosphorylated D274N Mutant of Aurora-a
- 1ol7: Structure of Human Aurora-a 122-403 Phosphorylated on Thr287, Thr288
- 1om1: Crystal Structure of Maize Ck2 Alpha in Complex with Iqa
- 1ouk: The Structure of P38 Alpha in Complex with a Pyridinylimidazole Inhibitor
- 1ouy: The Structure of P38 Alpha in Complex with a Dihydropyrido- Pyrimidine Inhibitor
- 1ove: The Structure of P38 Alpha in Complex with a Dihydroquinolinone
- 1oz1: P38 Mitogen-activated Kinase in Complex with 4-azaindole Inhibitor
- 1pf8: Crystal Structure of Human Cyclin-dependent Kinase 2 Complexed with a Nucleoside Inhibitor
- 1pjk: Crystal Structure of a C-terminal Deletion Mutant of Human Protein Kinase Ck2 Catalytic Subunit
- 1plo: Transforming Growth Factor-beta Type II Receptor Extracellular Domain
- 1py5: Crystal Structure of Tgf-beta Receptor I Kinase with Inhibitor
- 1pyx: Gsk-3 Beta Complexed with Amp-pnp
- 1q24: Pka Double Mutant Model of Pkb in Complex with Mgatp
- 1q3d: Gsk-3 Beta Complexed with Staurosporine
- 1q3w: Gsk-3 Beta Complexed with Alsterpaullone
- 1q41: Gsk-3 Beta Complexed with Indirubin-3'-monoxime
- 1q4l: Gsk-3 Beta Complexed with Inhibitor I-5
- 1q5k: Crystal Structure of Glycogen Synthase Kinase 3 in Complexed with Inhibitor
- 1q61: Pka Triple Mutant Model of Pkb
- 1q62: Pka Double Mutant Model of Pkb
- 1q8t: The Catalytic Subunit of Camp-dependent Protein Kinase (pka) in Complex with Rho-kinase Inhibitor Y-27632
- 1q8u: The Catalytic Subunit of Camp-dependent Protein Kinase in Complex with Rho-kinase Inhibitor H-1152p
- 1q8w: The Catalytic Subunit of Camp-dependent Protein Kinase in Complex with Rho-kinase Inhibitor Fasudil (ha-1077)
- 1qf8: Truncated Form of Casein Kinase II Beta Subunit (2-182) from Homo Sapiens
- 1r0e: Glycogen Synthase Kinase-3 Beta in Complex with 3-indolyl-4- Arylmaleimide Inhibitor
- 1r2a: The Molecular Basis for Protein Kinase a Anchoring Revealed by Solution Nmr
- 1r39: The Structure of P38ALPHA
- 1r3c: The Structure of P38ALPHA C162S Mutant
- 1rdq: Hydrolysis of Atp in The Crystal of Y204A Mutant of Camp- Dependent Protein Kinase
- 1re8: Crystal Structure of Camp-dependent Protein Kinase Complexed with Balanol Analog 2
- 1rej: Crystal Structure of Camp-dependent Protein Kinase Complexed with Balanol Analog 1
- 1rek: Crystal Structure of Camp-dependent Protein Kinase Complexed with Balanol Analog 8
- 1rew: Structural Refinement of The Complex of Bone Morphogenetic Protein 2 and Its Type Ia Receptor
- 1rgs: Regulatory Subunit of Camp Dependent Protein Kinase
- 1rqf: Structure of Ck2 Beta Subunit Crystallized in The Presence of a P21WAF1 Peptide
- 1rw8: Crystal Structure of Tgf-beta Receptor I Kinase with Atp Site Inhibitor
- 1rwi: Extracellular Domain of Mycobacterium Tuberculosis Pknd
- 1rwl: Extracellular Domain of Mycobacterium Tuberculosis Pknd
- 1s4y: Crystal Structure of The Activin/actriib Extracellular Domain
- 1s9i: X-ray Structure of The Human Mitogen-activated Protein Kinase Kinase 2 (mek2)in a Complex with Ligand and Mgatp
- 1s9j: X-ray Structure of The Human Mitogen-activated Protein Kinase Kinase 1 (mek1) in a Complex with Ligand and Mgatp
- 1smh: Protein Kinase a Variant Complex with Completely Ordered N- Terminal Helix
- 1stc: Camp-dependent Protein Kinase, Alpha-catalytic Subunit in Complex with Staurosporine
- 1sve: Crystal Structure of Protein Kinase a in Complex with Azepane Derivative 1
- 1svg: Crystal Structure of Protein Kinase a in Complex with Azepane Derivative 4
- 1svh: Crystal Structure of Protein Kinase a in Complex with Azepane Derivative 8
- 1syk: Crystal Structure of E230Q Mutant of Camp-dependent Protein Kinase Reveals Unexpected Apoenzyme Conformation
- 1szm: Dual Binding Mode of Bisindolylmaleimide 2 to Protein Kinase a (pka)
- 1th8: Crystal Structures of The Adp and Atp Bound Forms of The Bacillus Anti-sigma Factor Spoiiab in Complex with The Anti-anti-sigma Spoiiaa: Inhibitory Complex with Adp, Crystal Form II
- 1thn: Crystal Structures of The Adp and Atp Bound Forms of The Bacillus Anti-sigma Factor Spoiiab in Complex with The Anti-anti-sigma Spoiiaa: Inhibitory Complex with Adp, Crystal Form I
- 1tid: Crystal Structures of The Adp and Atp Bound Forms of The Bacillus Anti-sigma Factor Spoiiab in Complex with The Anti-anti-sigma Spoiiaa: Poised for Phosphorylation Complex with Atp, Crystal Form I
- 1til: Crystal Structures of The Adp and Atp Bound Forms of The Bacillus Anti-sigma Factor Spoiiab in Complex with The Anti-anti-sigma Spoiiaa:poised for Phosphorylation Complex with Atp, Crystal Form II
- 3e3p: Glycogen Synthase Kinase from Leishmania Major
- 1tvo: The Structure of Erk2 in Complex with a Small Molecule Inhibitor
- 1ua2: Crystal Structure of Human Cdk7
- 1ukh: Structural Basis for The Selective Inhibition of Jnk1 by The Scaffolding Protein Jip1 and Sp600125
- 1uki: Structural Basis for The Selective Inhibition of Jnk1 by The Scaffolding Protein Jip1 and Sp600125
- 1urc: Cyclin a Binding Groove Inhibitor Ace-arg-lys-leu- Phe-gly
- 1urw: Cdk2 in Complex with an Imidazo[1,2-b]pyridazine
- 1uti: Mona/gads SH3C in Complex with Hpk Derived Peptide
- 1uu3: Structure of Human Pdk1 Kinase Domain in Complex with Ly333531
- 1uu7: Structure of Human Pdk1 Kinase Domain in Complex with Bim-2
- 1uu8: Structure of Human Pdk1 Kinase Domain in Complex with Bim-1
- 1uu9: Structure of Human Pdk1 Kinase Domain in Complex with Bim-3
- 1uv5: Glycogen Synthase Kinase 3 Beta Complexed with 6-bromoindirubin-3'-oxime
- 1uvr: Structure of Human Pdk1 Kinase Domain in Complex with Bim-8
- 1uwh: The Complex of Wild Type B-raf and Bay439006
- 1uwj: The Complex of Mutant V599E B-raf and Bay439006
- 1v1k: Cdk2 in Complex with a Disubstituted 4, 6-bis Anilino Pyrimidine Cdk4 Inhibitor
- 1vd2: Solution Structure of The Pb1 Domain of Pkciota
- 1veb: Crystal Structure of Protein Kinase a in Complex with Azepane Derivative 5
- 1vjy: Crystal Structure of a Naphthyridine Inhibitor of Human Tgf- Beta Type I Receptor
- 1vyw: Structure of Cdk2/cyclin a with Pnu-292137
- 1vyz: Structure of Cdk2 Complexed with Pnu-181227
- 1vzo: The Structure of The N-terminal Kinase Domain of Msk1 Reveals a Novel Autoinhibitory Conformation for a Dual Kinase Protein
- 1w0x: Crystals Structure of Human Cdk2 in Complex with The Inhibitor Olomoucine.
- 1w1d: Crystal Structure of The Pdk1 Pleckstrin Homology (ph) Domain Bound to Inositol (1,3,4,5)-tetrakisphosphate
- 1w1g: Crystal Structure of The Pdk1 Pleckstrin Homology (ph) Domain Bound to Dic4-phosphatidylinositol (3,4,5)- Trisphosphate
- 1w1h: Crystal Structure of The Pdk1 Pleckstrin Homology (ph) Domain
- 1w7h: P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor
- 1w82: P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor
- 1w83: P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor
- 1w84: P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor
- 1w8c: Co-crystal Structure of 6-cyclohexylmethoxy-8-isopropyl-9h- Purin-2-ylamine and Monomeric Cdk2
- 1w98: The Structural Basis of Cdk2 Activation by Cyclin E
- 1wak: X-ray Structure of Srpk1
- 1wbn: Fragment Based P38 Inhibitors
- 1wbo: Fragment Based P38 Inhibitors
- 1wbp: Srpk1 Bound to 9mer Docking Motif Peptide
- 1wbs: Identification of Novel P38 Alpha Map Kinase Inhibitors Using Fragment-based Lead Generation.
- 1wbt: Identification of Novel P38 Alpha Map Kinase Inhibitors Using Fragment-based Lead Generation.
- 1wbv: Identification of Novel P38 Alpha Map Kinase Inhibitors Using Fragment-based Lead Generation.
- 1wbw: Identification of Novel P38 Alpha Map Kinase Inhibitors Using Fragment-based Lead Generation.
- 1wcc: Screening for Fragment Binding by X-ray Crystallography
- 1wh4: Solution Structure of The Death Domain of Interleukin-1 Receptor-associated Kinase4 (irak4) from Mus Musculus
- 1wmh: Crystal Structure of a Pb1 Domain Complex of Protein Kinase C Iota and Par6 Alpha
- 1wmk: Human Death-associated Kinase Drp-1, Mutant S308D D40
- 1wrz: Calmodulin Complexed with a Peptide from a Human Death- Associated Protein Kinase
- 1wvw: Crystal Structures of Kinase Domain of Dap Kinase in Complex with Small Molecular Inhibitors
- 1wvx: Crystal Structures of Kinase Domain of Dap Kinase in Complex with Small Molecular Inhibitors
- 1wvy: Crystal Structures of Kinase Domain of Dap Kinase in Complex with Small Molecular Inhibitors
- 1wxm: Solution Structure of The N-terminal Ras-binding Domain (rbd) in Human A-raf Kinase
- 1wzy: Crystal Structure of Human Erk2 Complexed with a Pyrazolopyridazine Derivative
- 1x9x: Solution Structure of Dimeric Sam Domain from Mapkkk Ste11
- 1xh4: Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase a and Mutants
- 1xh5: Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase a and Mutants
- 1xh6: Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase a and Mutants
- 1xh7: Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase a and Mutants
- 1xh8: Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase a and Mutants
- 1xh9: Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase a and Mutants
- 1xha: Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase a and Mutants
- 2xmy: Discovery and Characterisation of 2-anilino-4-(thiazol-5-yl) Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents
- 1xo2: Crystal Structure of a Human Cyclin-dependent Kinase 6 Complex with a Flavonol Inhibitor, Fisetin
- 1xqz: Crystal Structure of Hpim-1 Kinase at 2.1 a Resolution
- 1xr1: Crystal Structure of Hpim-1 Kinase in Complex with Amp-pnp at 2.1 a Resolution
- 1xte: Crystal Structure of Cisk-px Domain
- 1xtn: Crystal Structure of Cisk-px Domain with Sulfates
- 1xws: Crystal Structure of The Human Pim1 Kinase Domain
- 2x1n: Truncation and Optimisation of Peptide Inhibitors of Cdk2, Cyclin a through Structure Guided Design
- 1y8g: Catalytic and Ubiqutin-associated Domains of Mark2/par-1: Inactive Double Mutant with Selenomethionine
- 2wxv: Structure of Cdk2-cyclin a with a Pyrazolo(4,3-h) Quinazoline-3-carboxamide Inhibitor
- 1y8y: Crystal Structure of Human Cdk2 Complexed with a Pyrazolo[1, 5-a]pyrimidine Inhibitor
- 1y91: Crystal Structure of Human Cdk2 Complexed with a Pyrazolo[1, 5-a]pyrimidine Inhibitor
- 1ydr: Structure of Camp-dependent Protein Kinase, Alpha-catalytic Subunit in Complex with H7 Protein Kinase Inhibitor 1-(5- Isoquinolinesulfonyl)-2-methylpiperazine
- 1yds: Structure of Camp-dependent Protein Kinase, Alpha-catalytic Subunit in Complex with H8 Protein Kinase Inhibitor [n-(2- Methylamino)ethyl]-5-isoquinolinesulfonamide
- 1ydt: Structure of Camp-dependent Protein Kinase, Alpha-catalytic Subunit in Complex with H89 Protein Kinase Inhibitor N-[2- (4-bromocinnamylamino)ethyl]-5-isoquinoline
- 1ygo: Solution Structure of The Pelle Death Domain
- 1yhs: Crystal Structure of Pim-1 Bound to Staurosporine
- 1yhv: Crystal Structure of Pak1 Kinase Domain with Two Point Mutations (K299R, T423E)
- 1yhw: Crystal Structure of Pak1 Kinase Domain with One Point Mutations (K299R)
- 1yi3: Crystal Structure of Pim-1 Bound to Ly294002
- 1yi4: Structure of Pim-1 Bound to Adenosine
- 2wpa: Optimisation of 6,6-dimethyl Pyrrolo 3,4-c Pyrazoles: Identification of Pha-793887, a Potent Cdk Inhibitor Suitable for Intravenous Dosing
- 1ykr: Crystal Structure of Cdk2 with an Aminoimidazo Pyridine Inhibitor
- 1yqj: Crystal Structure of P38 Alpha in Complex with a Selective Pyridazine Inhibitor
- 1yr5: 1.7-a Structure of Calmodulin Bound to a Peptide from Dap Kinase
- 1yrp: Catalytic Domain of Human Zip Kinase Phosphorylated at Thr265
- 2wip: Structure of Cdk2-cyclin a Complexed with 8-anilino-1- Methyl-4,5-dihydro-1h-pyrazolo[4,3-h] Quinazoline-3- Carboxylic Acid
- 2wih: Structure of Cdk2-cyclin a with Pha-848125
- 2whb: Truncation and Optimisation of Peptide Inhibitors of Cdk2, Cyclin a through Structure Guided Design
- 1yw2: Mutated Mus Musculus P38 Kinase (mp38)
- 1ywr: Crystal Structure Analysis of Inactive P38 Kinase Domain in Complex with a Monocyclic Pyrazolone Inhibitor
- 1ywv: Crystal Structures of Proto-oncogene Kinase Pim1: a Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma
- 2wfy: Truncation and Optimisation of Peptide Inhibitors of Cdk2, Cyclin a through Structure Guided Design
- 2wev: Truncation and Optimisation of Peptide Inhibitors of Cdk2, Cyclin a through Structure Guided Design
- 1yxs: Crystal Structure of Kinase Pim1 with P123M Mutation
- 1yxt: Crystal Structure of Kinase Pim1 in Complex with Amppnp
- 1yxu: Crystal Structure of Kinase Pim1 in Complex with Amp
- 1yxv: Crystal Structure of Kinase Pim1 in Complex with 3,4- Dihydroxy-1-methylquinolin-2(1h)-one
- 1yxx: Crystal Structure of Kinase Pim1 in Complex with (3e)-3-[(4- Hydroxyphenyl)imino]-1h-indol-2(3h)-one
- 1z5m: Crystal Structure of N1-[3-[[5-bromo-2-[[3-[(1- Pyrrolidinylcarbonyl)amino]phenyl]amino]-4- Pyrimidinyl]amino]propyl]-2,2-dimethylpropanediamide Complexed with Human Pdk1
- 1z9x: Human Drp-1 Kinase, W305S S308A D40 Mutant, Crystal Form with 3 Monomers in The Asymmetric Unit
- 2w1h: Fragment-based Discovery of The Pyrazol-4-yl Urea (at9283), a Multi-targeted Kinase Inhibitor with Potent Aurora Kinase Activity
- 1zlt: Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog
- 1zmu: Catalytic and Ubiqutin-associated Domains of Mark2/par-1: Wild Type
- 1zmv: Catalytic and Ubiqutin-associated Domains of Mark2/par-1: K82R Mutant
- 1zmw: Catalytic and Ubiqutin-associated Domains of Mark2/par-1: T208A/S212A Inactive Double Mutant
- 1zoe: Crystal Structure of Protein Kinase Ck2 in Complex with Tbb- Derivatives Inhibitors
- 1zog: Crystal Structure of Protein Kinase Ck2 in Complex with Tbb- Derivatives
- 1zoh: Crystal Structure of Protein Kinase Ck2 in Complex with Tbb- Derivatives Inhibitors
- 1zsg: Beta Pix-sh3 Complexed with an Atypical Peptide from Alpha- Pak
- 1zxa: Solution Structure of The Coiled-coil Domain of Cgmp- Dependent Protein Kinase Ia
- 1zxe: Crystal Structure of EIF2ALPHA Protein Kinase Gcn2: D835N Inactivating Mutant in Apo Form
- 1zy4: Crystal Structure of EIF2ALPHA Protein Kinase Gcn2: R794G Hyperactivating Mutant in Apo Form.
- 1zy5: Crystal Structure of EIF2ALPHA Protein Kinase Gcn2: R794G Hyperactivating Mutant Complexed with Amppnp.
- 1zyc: Crystal Structure of EIF2ALPHA Protein Kinase Gcn2: Wild- Type in Apo Form.
- 1zyd: Crystal Structure of EIF2ALPHA Protein Kinase Gcn2: Wild- Type Complexed with Atp.
- 1zyj: Human P38 Map Kinase in Complex with Inhibitor 1a
- 1zys: Co-crystal Structure of Checkpoint Kinase Chk1 with a Pyrrolo-pyridine Inhibitor
- 1zz2: Two Classes of P38ALPHA Map Kinase Inhibitors Having a Common Diphenylether Core but Exhibiting Divergent Binding Modes
- 1zzl: Crystal Structure of P38 with Triazolopyridine
- 2a0c: Human Cdk2 in Complex with Olomoucine Ii, a Novel 2,6,9- Trisubstituted Purine Cyclin-dependent Kinase Inhibitor
- 2a0t: Nmr Structure of The Fha1 Domain of Rad53 in Complex with a Biological Relevant Phosphopeptide Derived from Madt1
- 2a27: Human Drp-1 Kinase, W305S S308A D40 Mutant, Crystal Form with 8 Monomers in The Asymmetric Unit
- 2a2a: High-resolution Crystallographic Analysis of The Autoinhibited Conformation of a Human Death-associated Protein Kinase
- 2a4l: Human Cyclin-dependent Kinase 2 in Complex with Roscovitine
- 2a9i: Molecular Structure of The Interleukin-1 Receptor- Associated Kinase-4 Death Domain
- 2ac3: Structure of Human Mnk2 Kinase Domain
- 2ac5: Structure of Human Mnk2 Kinase Domain Mutant D228G
- 2v22: Replace: a Strategy for Iterative Design of Cyclin Binding Groove Inhibitors
- 2v0d: Crystal Structure of Human Cdk2 Complexed with a Thiazolidinone Inhibitor
- 2uzo: Crystal Structure of Human Cdk2 Complexed with a Thiazolidinone Inhibitor
- 2uzn: Crystal Structure of Human Cdk2 Complexed with a Thiazolidinone Inhibitor
- 2uzl: Crystal Structure of Human Cdk2 Complexed with a Thiazolidinone Inhibitor
- 2uze: Crystal Structure of Human Cdk2 Complexed with a Thiazolidinone Inhibitor
- 2uzd: Crystal Structure of Human Cdk2 Complexed with a Thiazolidinone Inhibitor
- 2uzb: Crystal Structure of Human Cdk2 Complexed with a Thiazolidinone Inhibitor
- 2ayp: Crystal Structure of Chk1 with an Indol Inhibitor
- 2b1p: Inhibitor Complex of Jnk3
- 2b52: Human Cyclin Dependent Kinase 2 (cdk2) Complexed with Dph- 042562
- 2b53: Human Cyclin Dependent Kinase 2 (cdk2) Complexed with Din- 234325
- 2b54: Human Cyclin Dependent Kinase 2 (ckd2)complexed with Din- 232305
- 2b55: Human Cyclin Dependent Kinase 2 (cdk2) Complexed with Indenopyraxole Din-101312
- 2b9f: Crystal Structure of Non-phosphorylated Fus3
- 2b9h: Crystal Structure of Fus3 with a Docking Motif from Ste7
- 2b9i: Crystal Structure of Fus3 with a Docking Motif from Msg5
- 2b9j: Crystal Structure of Fus3 with a Docking Motif from Far1
- 2baj: P38ALPHA Bound to Pyrazolourea
- 2bak: P38ALPHA Map Kinase Bound to Mpaq
- 2bal: P38ALPHA Map Kinase Bound to Pyrazoloamine
- 2baq: P38ALPHA Bound to Ro3201195
- 2bhe: Human Cyclin Dependent Protein Kinase 2 in Complex with The Inhibitor 5-bromo-indirubine
- 2bhh: Human Cyclin Dependent Protein Kinase 2 in Complex with The Inhibitor 4-hydroxypiperindinesulfonyl-indirubine
- 2bik: Human Pim1 Phosphorylated on Ser261
- 2bil: The Human Protein Kinase Pim1 in Complex with Its Consensus Peptide Pimtide
- 2biy: Structure of PDK1-S241A Mutant Kinase Domain
- 2bkz: Structure of Cdk2-cyclin a with Pha-404611
- 2bmc: Aurora-2 T287D T288D Complexed with Pha-680632
- 2bpm: Structure of Cdk2-cyclin a with Pha-630529
- 2br1: Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-ligand Affinity
- 2brb: Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-ligand Affinity
- 2brg: Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-ligand Affinity
- 2brh: Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-ligand Affinity
- 2brm: Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-ligand Affinity
- 2brn: Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-ligand Affinity
- 2bro: Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-ligand Affinity
- 2btr: Structure of Cdk2 Complexed with Pnu-198873
- 2bts: Structure of Cdk2 Complexed with Pnu-230032
- 2buj: Crystal Structure of The Human Serine-threonine Kinase 16 in Complex with Staurosporine
- 2bva: Crystal Structure of The Human P21-activated Kinase 4
- 2bzh: Crystal Structure of The Human Pim1 in Complex with a Ruthenium Organometallic Ligand Ru1
- 2bzi: Crystal Structure of The Human Pim1 in Complex with a Ruthenium Organometallic Ligand Ru2
- 2bzj: Crystal Structure of The Human Pim1 in Complex with a Ruthenium Organometallic Ligand Ru3
- 2bzk: Crystal Structure of The Human Pim1 in Complex with Amppnp and Pimtide
- 2c1a: Structure of Camp-dependent Protein Kinase Complexed with Isoquinoline-5-sulfonic Acid (2-(2-(4-chlorobenzyloxy) Ethylamino)ethyl)amide
- 2c1b: Structure of Camp-dependent Protein Kinase Complexed with ( 4r,2s)-5'-(4-(4-chlorobenzyloxy)pyrrolidin-2- Ylmethanesulfonyl)isoquinoline
- 2c30: Crystal Structure of The Human P21-activated Kinase 6
- 2c3i: Crystal Structure of Human Pim1 in Complex with Imidazopyridazin I
- 2c3j: Identification of a Buried Pocket for Potent and Selective Inhibition of Chk1: Prediction and Verification
- 2c3k: Identification of a Buried Pocket for Potent and Selective Inhibition of Chk1: Prediction and Verification
- 2c3l: Identification of a Buried Pocket for Potent and Selective Inhibition of Chk1: Prediction and Verification
- 2c4g: Structure of Cdk2-cyclin a with Pha-533514
- 2c5n: Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design
- 2c5o: Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design
- 2c5v: Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design
- 2c5x: Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design
- 2c5y: Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design
- 2c60: Crystal Structure of Human Mitogen-activated Protein Kinase Kinase Kinase 3 Isoform 2 Phox Domain at 1.25 a Resolution
- 2c68: Crystal Structure of The Human Cdk2 Complexed with The Triazolopyrimidine Inhibitor
- 2c69: Crystal Structure of The Human Cdk2 Complexed with The Triazolopyrimidine Inhibitor
- 2c6d: Aurora a Kinase Activated Mutant (T287D) in Complex with Adpnp
- 2c6e: Aurora a Kinase Activated Mutant (T287D) in Complex with a 5-aminopyrimidinyl Quinazoline Inhibitor
- 2c6i: Crystal Structure of The Human Cdk2 Complexed with The Triazolopyrimidine Inhibitor
- 2c6k: Crystal Structure of The Human Cdk2 Complexed with The Triazolopyrimidine Inhibitor
- 2c6l: Crystal Structure of The Human Cdk2 Complexed with The Triazolopyrimidine Inhibitor
- 2c6m: Crystal Structure of The Human Cdk2 Complexed with The Triazolopyrimidine Inhibitor
- 2c6o: Crystal Structure of The Human Cdk2 Complexed with The Triazolopyrimidine Inhibitor
- 2c6t: Crystal Structure of The Human Cdk2 Complexed with The Triazolopyrimidine Inhibitor
- 2cdz: Crystal Structure of The Human P21-activated Kinase 4 in Complex with CGP74514A
- 2cgu: Identification of Chemically Diverse Chk1 Inhibitors by Receptor-based Virtual Screening
- 2cgv: Identification of Chemically Diverse Chk1 Inhibitors by Receptor-based Virtual Screening
- 2cgw: Identification of Chemically Diverse Chk1 Inhibitors by Receptor-based Virtual Screening
- 2cgx: Identification of Chemically Diverse Chk1 Inhibitors by Receptor-based Virtual Screening
- 2cjm: Mechanism of Cdk Inhibition by Active Site Phosphorylation: Cdk2 Y15P T160P in Complex with Cyclin a Structure
- 2clx: 4-arylazo-3,5-diamino-1h-pyrazole Cdk Inhibitors: Sar Study, Crystal Structure in Complex with Cdk2, Selectivity, and Cellular Effects
- 2cos: Solution Structure of Rsgi Ruh-038, a Uba Domain from Mouse Lats2 (large Tumor Suppressor Homolog 2)
- 2cpk: Crystal Structure of The Catalytic Subunit of Cyclic Adenosine Monophosphate-dependent Protein Kinase
- 2cu1: Solution Structure of The Pb1 Domain of Human Protein Kinase MEKK2B
- 2df6: Crystal Structure of The Sh3 Domain of Betapix in Complex with a High Affinity Peptide from Pak2
- 2drn: Docking and Dimerization Domain (d/d) of The Type Ii-alpha Regulatory Subunity of Protein Kinase a (pka) in Complex with a Peptide from an A-kinase Anchoring Protein
- 2erz: Crystal Structure of C-amp Dependent Kinase (pka) Bound to Hydroxyfasudil
- 2esm: Crystal Structure of Rock 1 Bound to Fasudil
- 2etk: Crystal Structure of Rock 1 Bound to Hydroxyfasudil
- 2etr: Crystal Structure of Rock I Bound to Y-27632
- 2euf: X-ray Structure of Human Cdk6-vcyclin in Complex with The Inhibitor Pd0332991
- 2eva: Structural Basis for The Interaction of Tak1 Kinase with Its Activating Protein Tab1
- 2ewa: Dual Binding Mode of Pyridinylimidazole to Map Kinase P38
- 2exc: Inhibitor Complex of Jnk3
- 2exm: Human Cdk2 in Complex with Isopentenyladenine
- 2ezw: Solution Structure of The Docking and Dimerization Domain of The Type I Alpha Regulatory Subunit of Protein Kinase a (rialpha D/d)
- 2f2c: X-ray Structure of Human Cdk6-vcyclinwith The Inhibitor Aminopurvalanol
- 2f2u: Crystal Structure of The Rho-kinase Kinase Domain
- 2f49: Crystal Structure of Fus3 in Complex with a Ste5 Peptide
- 2f57: Crystal Structure of The Human P21-activated Kinase 5
- 2f7e: Pka Complexed with (s)-2-(1h-indol-3-yl)-1-(5-isoquinolin-6- Yl-pyridin-3-yloxymethyl-etylamine
- 2f7x: Protein Kinase a Bound to (s)-2-(1h-indol-3-yl)-1-[5-((e)-2- Pyridin-4-yl-vinyl)-pyridin-3-yloxymethyl]-ethylamine
- 2f7z: Protein Kinase a Bound to (r)-1-(1h-indol-3-ylmethyl)-2-(2- Pyridin-4-yl-[1,7]naphtyridin-5-yloxy)-ehylamine
- 2f9g: Crystal Structure of Fus3 Phosphorylated on Tyr182
- 2fa2: Crystal Structure of Fus3 without a Peptide from Ste5
- 2fb8: Structure of The B-raf Kinase Domain Bound to Sb-590885
- 2fk9: Human Protein Kinase C, Eta
- 2fsl: Mitogen Activated Protein Kinase P38ALPHA (D176A+F327S) Activating Mutant Form-a
- 2fsm: Mitogen Activated Protein Kinase P38ALPHA (D176A+F327S) Activating Mutant Form-b
- 2fso: Mitogen Activated Protein Kinase P38ALPHA (D176A) Activating Mutant
- 2fst: Mitogen Activated Protein Kinase P38ALPHA (D176A+F327L) Activating Mutant
- 2fum: Catalytic Domain of Protein Kinase Pknb from Mycobacterium Tuberculosis in Complex with Mitoxantrone
- 2fvd: Cyclin Dependent Kinase 2 (cdk2) with Diaminopyrimidine Inhibitor
- 2fys: Crystal Structure of Erk2 Complex with Kim Peptide Derived from Mkp3
- 2g01: Pyrazoloquinolones as Novel, Selective Jnk1 Inhibitors
- 2g9x: Structure of Thr 160 Phosphorylated Cdk2/cyclin a in Complex with The Inhibitor Nu6271
- 2gbl: Crystal Structure of Full Length Circadian Clock Protein Kaic with Phosphorylation Sites
- 2gcd: Tao2 Kinase Domain-staurosporine Structure
- 2gdo: 4-(aminoalkylamino)-3-benzimidazole-quinolinones as Potent Chk1 Inhibitors
- 2gfc: Camp-dependent Protein Kinase Pka Catalytic Subunit with Pki-5-24
- 2gfs: P38 Kinase Crystal Structure in Complex with Ro3201195
- 2ghg: H-chk1 Complexed with A431994
- 2ghl: Mutant Mus Musculus P38 Kinase Domain in Complex with Inhibitor Pg-874743
- 2ghm: Mutated Map Kinase P38 (mus Musculus) in Complex with Inhbitor Pg-895449
- 2gu8: Discovery of 2-pyrimidyl-5-amidothiophenes as Novel and Potent Inhibitors for Akt: Synthesis and Sar Studies
- 2h9r: Docking and Dimerization Domain (d/d) of The Regulatory Subunit of The Type Ii-alpha Camp-dependent Protein Kinase a Associated with a Peptide Derived from an A-kinase Anchoring Protein (akap)
- 2iw6: Structure of Human Thr160-phospho Cdk2-cyclin a Complexed with a Bisanilinopyrimidine Inhibitor
- 2iw8: Structure of Human Thr160-phospho Cdk2-cyclin a F82H-L83V- H84D Mutant with an O6-cyclohexylmethylguanine Inhibitor
- 2iw9: Structure of Human Thr160-phospho Cdk2-cyclin a Complexed with a Bisanilinopyrimidine Inhibitor
- 2j0i: Crystal Structure of The Human P21-activated Kinase 4
- 2j4z: Structure of Aurora-2 in Complex with Pha-680626
- 2j9m: Crystal Structure of Cdk2 in Complex with Macrocyclic Aminopyrimidine
- 3ndm: Crystal Structure of Rho-associated Protein Kinase (rock1) with a Potent Isoquinolone Derivative
- 2xix: Protein Kinase Pim-1 in Complex with Fragment-1 from Crystallographic Fragment Screen
- 2xiy: Protein Kinase Pim-1 in Complex with Fragment-2 from Crystallographic Fragment Screen
- 2xiz: Protein Kinase Pim-1 in Complex with Fragment-3 from Crystallographic Fragment Screen
- 2xj0: Protein Kinase Pim-1 in Complex with Fragment-4 from Crystallographic Fragment Screen
- 2xj1: Protein Kinase Pim-1 in Complex with Small Molecule Inibitor
- 3pna: Crystal Structure of Camp Bound (91-244)ria Subunit of Camp-dependent Protein Kinase
- 4a7c: Crystal Structure of Pim1 Kinase with Etp46546
- 4a9y: P38ALPHA Map Kinase Bound to Cmpd 8
- 4aa0: P38ALPHA Map Kinase Bound to Cmpd 2
- 4aa4: P38ALPHA Map Kinase Bound to Cmpd 22
- 4aa5: P38ALPHA Map Kinase Bound to Cmpd 33
- 4app: Crystal Structure of The Human P21-activated Kinase 4 in Complex with (s)-n-(5-(3-benzyl-1-methylpiperazine-4- Carbonyl)-6,6-dimethyl-1,4,5,6-tetrahydropyrrolo(3,4-c) Pyrazol-3-yl)-3-phenoxybenzamide
- 4alu: Benzofuropyrimidinone Inhibitors of Pim-1
- 4alv: Benzofuropyrimidinone Inhibitors of Pim-1
- 4alw: Benzofuropyrimidinone Inhibitors of Pim-1
- 4g1w: Crystal Structure of Jnk1 in Complex with Jip1 Peptide and 7-fluoro-3- [4-(2-hydroxy-ethanesulfonyl)-benzyl]-4-oxo-1-phenyl-1,4-dihydro- Quinoline-2-carboxylic Acid Methyl Ester
- 4hys: Crystal Structure of Jnk1 in Complex with Jip1 Peptide and 4-(4- Indazol-1-yl-pyrimidin-2-ylamino)-cyclohexan
- 4hyu: Crystal Structure of Jnk1 in Complex with Jip1 Peptide and 4-{4-[4-(3- Methanesulfonyl-propoxy)-indazol-1-yl]-pyrimidin-2-ylamino}- Cyclohexan
- 4izy: Crystal Structure of Jnk1 in Complex with Jip1 Peptide and 4-{4-[4-(4- Methanesulfonyl-piperidin-1-yl)-indol-1-yl]-pyrimidin-2-ylamino}- Cyclohexan
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