EC 2.7.1.40 - ATP:pyruvate 2- O- phosphotransferase (pyruvate kinase)

3D structures of EC 2.7.1.40 - pyruvate kinase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1a3w: Pyruvate Kinase from Saccharomyces Cerevisiae Complexed with Fbp, Pg, Mn2+ and K+
2. 1a3x: Pyruvate Kinase from Saccharomyces Cerevisiae Complexed with Pg, Mn2+ and K+
3. 1a49: Bis Mg-atp-k-oxalate Complex of Pyruvate Kinase
4. 1a5u: Pyruvate Kinase Complex with Bis Mg-atp-na-oxalate
5. 1aqf: Pyruvate Kinase from Rabbit Muscle with Mg, K, and L- Phospholactate
6. 1e0t: R292D Mutant of E. Coli Pyruvate Kinase
7. 1e0u: Structure R271L Mutant of E. Coli Pyruvate Kinase
8. 1f3w: Recombinant Rabbit Muscle Pyruvate Kinase
9. 1f3x: S402P Mutant of Rabbit Muscle Pyruvate Kinase
10. 3n25: The Structure of Muscle Pyruvate Kinase in Complex with Proline, Pyruvate, and Mn2+
11. 3me3: Activator-bound Structure of Human Pyruvate Kinase M2
12. 3ma8: Crystal Structure of Cgd1_2040, a Pyruvate Kinase from Cryptosporidium Parvum
13. 3ktx: Crystal Structure of Leishmania Mexicana Pyruvate Kinase (lmpyk)in Complex with 1,3,6,8-pyrenetetrasulfonic Acid
14. 6tti: Pkm2 in Complex with Compound 6
15. 6ttq: Pkm2 in Complex with Compound 10
16. 3khd: Crystal Structure of PFF1300W.
17. 3is4: Crystal Structure of Leishmania Mexicana Pyruvate Kinase (lmpyk)in Complex with 1,3,6,8-pyrenetetrasulfonic Acid
18. 1pkl: The Structure of Leishmania Pyruvate Kinase
19. 1pkm: The Refined Three-dimensional Structure of Cat Muscle (m1) Pyruvate Kinase, at a Resolution of 2.6 Angstroms
20. 1pkn: Structure of Rabbit Muscle Pyruvate Kinase Complexed with Mn2+, K+, and Pyruvate
21. 1pky: Pyruvate Kinase from E. Coli in The T-state
22. 1pyk: Crystal Structure of Cat Muscle Pyruvate Kinase at a Resolution of 2.6 Angstroms
23. 3hqq: Crystal Structure of Leishmania Mexicana Pyruvate Kinase (lmpyk) in Complex with Fructose 2,6 Bisphosphate
24. 3hqp: Crystal Structure of Leishmania Mexicana Pyruvate Kinase (lmpyk) in Complex with Atp, Oxalate and Fructose 2,6 Bisphosphate
25. 3hqo: Crystal Structures of Leishmania Mexicana Pyruvate Kinase (lmpyk) in Complex with Atp and Oxalate
26. 3hqn: Apo Crystal Structure of Leishmania Mexicana(lmpyk)pyruvate Kinase
27. 3h6o: Activator-bound Structure of Human Pyruvate Kinase M2
28. 3gr4: Activator-bound Structure of Human Pyruvate Kinase M2
29. 3gqy: Activator-bound Structure of Human Pyruvate Kinase M2
30. 3gg8: Crystal Structure of The Toxoplasma Gondii Pyruvate Kinase N Terminal Truncated
31. 3g2g: S437Y Mutant of Human Muscle Pyruvate Kinase, Isoform M2
32. 1t5a: Human Pyruvate Kinase M2
33. 3eoe: Crystal Structure of Pyruvate Kinase from Toxoplasma Gondii, 55.m00007
34. 3e0w: Crystal Structure of Pyruvate Kinase from Leishmania Mexicana
35. 3e0v: Crystal Structure of Pyruvate Kinase from Leishmania Mexicana in Complex with Sulphate Ions
36. 3bjt: Pyruvate Kinase M2 Is a Phosphotyrosine Binding Protein
37. 3bjf: Pyruvate Kinase M2 Is a Phosphotyrosine Binding Protein
38. 1zjh: Structure of Human Muscle Pyruvate Kinase (pkm2)
39. 2vgi: Human Erythrocyte Pyruvate Kinase: R486W Mutant
40. 2vgg: Human Erythrocyte Pyruvate Kinase: R479H Mutant
41. 2vgf: Human Erythrocyte Pyruvate Kinase: T384M Mutant
42. 2vgb: Human Erythrocyte Pyruvate Kinase
43. 2e28: Crystal Structure Analysis of Pyruvate Kinase from Bacillus Stearothermophilus
44. 6b6u: Pyruvate Kinase M2 Mutant - S437Y
45. 2g50: The Location of The Allosteric Amino Acid Binding Site of Muscle Pyruvate Kinase.
46. 6wp6: Pyruvate Kinase M2 MUTANT-S37E K433E
47. 6wp5: Pyruvate Kinase M2 MUTANT-S37D
48. 6wp4: Pyruvate Kinase M2 MUTANT-S37E
49. 6wp3: Pyruvate Kinase M2 MUTANT-K433Q
50. 6ksh: Crystal Structure of Pyruvate Kinase (pyk) from Plasmodium Falciparum in Complex with Oxalate and Atp
51. 3pp7: Crystal Structure of Leishmania Mexicana Pyruvate Kinase in Complex with The Drug Suramin, an Inhibitor of Glycolysis.
52. 6k0k: Crystal Structure of Escherichia Coli Pyruvate Kinase II
53. 6jfb: Crystal Structure of Human Pyruvate Kinase M2 Isoform
54. 6v76: Crystal Structure of Human Pkm2 in Complex with L-valine
55. 6v75: Crystal Structure of Human Pkm2 in Complex with L-aspartate
56. 6v74: Crystal Structure of Human Pkm2 in Complex with L-asparagine
57. 3qv6: Crystal Structure of Leishmania Mexicana Pyruvate Kinase(lmpyk)in Complex with Acid Blue 80.
58. 3qv7: Crystal Structure of Leishmania Mexicana Pyruvate Kinase(lmpyk)in Complex with Ponceau S and Acid Blue 25.
59. 3qv8: Crystal Structure of Leishmania Mexicana Pyruvate Kinase(lmpyk)in Complex with Benzothiazole-2,5-disulfonic Acid.
60. 3qv9: Crystal Structure of Trypanosoma Cruzi Pyruvate Kinase(tcpyk)in Complex with Ponceau S.
61. 3t05: Crystal Structure of S. Aureus Pyruvate Kinase
62. 3t07: Crystal Structure of S. Aureus Pyruvate Kinase in Complex with a Naturally Occurring Bis-indole Alkaloid
63. 6qxl: Crystal Structure of Pyruvate Kinase II (pyka) from Pseudomonas Aeruginosa in Complex with Sodium Malonate, Magnesium and Glucose-6- Phosphate
64. 3qtg: Crystal Structure of Pyruvate Kinase from Pyrobaculum Aerophilum
65. 6p0y: Cryptosporidium Parvum Pyruvate Kinase in Complex with Adp
66. 6nub: Pyruvate Kinase M2 Mutant - S437Y in Complex with L-serine
67. 6nu5: Pyruvate Kinase M2 Mutant - S437Y in Complex with L-cysteine
68. 6nu1: Crystal Structure of Human Pkm2 in Complex with L-cysteine
69. 6nn8: The Structure of Human Liver Pyruvate Kinase, HLPYK-S531E
70. 6nn7: The Structure of Human Liver Pyruvate Kinase, Hlpyk-ggg
71. 6nn5: The Structure of Human Liver Pyruvate Kinase, HLPYK-W527H
72. 6nn4: The Structure of Human Liver Pyruvate Kinase, HLPYK-D499N, in Complex with Fru-1,6-bp
73. 3t0t: Crystal Structure of S. Aureus Pyruvate Kinase
74. 3srk: A New Class of Suicide Inhibitor Blocks Nucleotide Binding to Pyruvate Kinase
75. 3srd: Human M2 Pyruvate Kinase in Complex with Fructose 1-6 Bisphosphate and Oxalate.
76. 3srf: Human M1 Pyruvate Kinase
77. 3srh: Human M2 Pyruvate Kinase
78. 3u2z: Activator-bound Structure of Human Pyruvate Kinase M2
79. 6ito: Crystal Structure of Pyruvate Kinase (pyk) from Mycobacterium Tuberculosis in Complex with Oxalate, Amp and Inhibitor Ribose 5- Phosphate
80. 4b2d: Human Pkm2 with L-serine and Fbp Bound.
81. 4drs: Crystal Structure of Cryptosporidium Parvum Pyruvate Kinase
82. 4g1n: Pkm2 in Complex with an Activator
83. 6su1: Trypanosoma Congolense Pyruvate Kinase in Complex with Citrate and Glycerol
84. 6su2: Trypanosoma Congolense Pyruvate Kinase in Complex with Citrate and Glycerol
85. 4ima: The Structure of C436M-HLPYK in Complex with Citrate/mn/atp/fru-1,6-bp
86. 4ip7: Structure of The S12D Variant of Human Liver Pyruvate Kinase in Complex with Citrate and Fbp.
87. 4fxf: Structure of M2 Pyruvate Kinase in Complex with Phenylalanine
88. 4fxj: Structure of M2 Pyruvate Kinase in Complex with Phenylalanine
89. 6gg6: Crystal Structure of M2 Pyk in Complex with Serine.
90. 6gg5: Crystal Structure of M2 Pyk in Complex with Tryptophan.
91. 6gg4: Crystal Structure of M2 Pyk in Complex with Phenyalanine.
92. 6gg3: Crystal Structure of M2 Pyk in Complex with Alanine.
93. 4jpg: 2-((1h-benzo[d]imidazol-1-yl)methyl)-4h-pyrido[1,2-a]pyrimidin-4-ones as Novel Pkm2 Activators
94. 6eck: Pyruvate Kinase Isoform L-type with Phosphorylated Ser113 (ps113) in Complex with Fbp
95. 6ech: Pyruvate Kinase Isoform L-type with Phosphorylated Ser12 (ps12) in Complex with Fbp
96. 6du6: Crystal Structure of The Pyruvate Kinase (pk1) from The Mosquito Aedes Aegypti
97. 4hyv: Pyruvate Kinase (pyk) from Trypanosoma Brucei in The Presence of Magnesium, Pep and F26BP
98. 4hyw: Pyruvate Kinase (pyk) from Trypanosoma Brucei in The Presence of Magnesium and F26BP
99. 4kct: Pyruvate Kinase (pyk) from Trypanosoma Brucei Soaked with Oxaloacetate
100. 4kcu: Pyruvate Kinase (pyk) from Trypanosoma Brucei Soaked with D-malate
101. 4kcv: Pyruvate Kinase (pyk) from Trypanosoma Brucei Soaked with 2- Oxoglutaric Acid
102. 4kcw: Pyruvate Kinase (pyk) from Trypanosoma Brucei Soaked with Oxalate
103. 4krz: Apo Crystal Structure of Pyruvate Kinase (pyk) from Trypanosoma Cruzi
104. 4ks0: Pyruvate Kinase (pyk) from Trypanosoma Cruzi in The Presence of Magnesium, Oxalate and F26BP
105. 5x1w: Pkm2 in Complex with Compound 5
106. 5x1v: Pkm2 in Complex with Compound 2
107. 5x0i: Crystal Structure of Pkm2 R399E Mutant Complexed with Fbp and Serine
108. 5wsc: Crystal of Pyruvate Kinase (pyk) from Mycobacterium Tuberculosis in Complex with Oxalate, Soaked with Allosteric Activators Amp and Glucose 6-phosphate
109. 5wsb: Pyruvate Kinase (pyk) from Mycobacterium Tuberculosis in Complex with Oxalate, Allosteric Activators Amp and Glucose 6-phosphate
110. 5wsa: Pyruvate Kinase (pyk) from Mycobacterium Tuberculosis in Complex with Oxalate and Allosteric Activator Glucose 6-phosphate
111. 5ws9: Pyruvate Kinase (pyk) from Mycobacterium Tuberculosis in Complex with Oxalate, Atp and Allosteric Activator Amp
112. 5ws8: Pyruvate Kinase (pyk) from Mycobacterium Tuberculosis in Complex with Oxalate
113. 5wrp: T-state Crystal Structure of Pyruvate Kinase from Mycobacterium Tuberculosis
114. 4qg6: Cystal Structure of Pkm2 Mutant 1
115. 4qg8: Crystal Structure of Pkm2 Mutant 2
116. 4qg9: Crystal Structure of Pkm2 Mutant 3
117. 4qgc: Crystal Structure of Pkm2 Mutant 4
118. 4rpp: Crystal Structure of Pkm2 Mutant 4 Bound with Fbp
119. 6ttf: Pkm2 in Complex with Compound 5
120. 6tth: Pkm2 in Complex with L-threonine
121. 4yng: Twinned Pyruvate Kinase from E. Coli in The T-state
122. 4yj5: Crystal Structure of Pkm2 Mutant
123. 4wj8: Human Pyruvate Kinase M2 Mutant C424A
124. 7oo1: Structure, Function and Characterization of a Second Pyruvate Kinase Isozyme in Pseudomonas Aeruginosa.
125. 7l21: Pyruvate Kinase M2 MUTANT-N70D