EC 1.14.99.1 - (5 Z ,8 Z ,11 Z ,14 Z ) - icosa- 5,8,11,14- tetraenoate,hydrogen- donor:oxygen oxidoreductase (prostaglandin- endoperoxide synthase)

3D structures of EC 1.14.99.1 - prostaglandin-endoperoxide synthase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1cqe: Prostaglandin H2 Synthase-1 Complex with Flurbiprofen
2. 1cvu: Crystal Structure of Arachidonic Acid Bound to The Cyclooxygenase Active Site of Cox-2
3. 1cx2: Cyclooxygenase-2 (prostaglandin Synthase-2) Complexed with a Selective Inhibitor, Sc-558
4. 1ddx: Crystal Structure of a Mixture of Arachidonic Acid and Prostaglandin Bound to The Cyclooxygenase Active Site of Cox-2: Prostaglandin Structure
5. 1diy: Crystal Structure of Arachidonic Acid Bound in The Cyclooxygenase Active Site of Pghs-1
6. 1ebv: Ovine Pghs-1 Complexed with Salicyl Hydroxamic Acid
7. 1eqg: The 2.6 Angstrom Model of Ovine Cox-1 Complexed with Ibuprofen
8. 1eqh: The 2.7 Angstrom Model of Ovine Cox-1 Complexed with Flurbiprofen
9. 1fe2: Crystal Structure of Dihomo-gamma-linoleic Acid Bound in The Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1.
10. 1ht5: The 2.75 Angstrom Resolution Model of Ovine Cox-1 Complexed with Methyl Ester Flurbiprofen
11. 1ht8: The 2.7 Angstrom Resolution Model of Ovine Cox-1 Complexed with Alclofenac
12. 1igx: Crystal Structure of Eicosapentanoic Acid Bound in The Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1.
13. 1igz: Crystal Structure of Linoleic Acid Bound in The Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1.
14. 6cox: Cyclooxygenase-2 (prostaglandin Synthase-2) Complexed with a Selective Inhibitor, Sc-558 in I222 Space Group
15. 5cox: Uninhibited Mouse Cyclooxygenase-2 (prostaglandin Synthase- 2)
16. 4cox: Cyclooxygenase-2 (prostaglandin Synthase-2) Complexed with a Non-selective Inhibitor, Indomethacin
17. 3pgh: Cyclooxygenase-2 (prostaglandin Synthase-2) Complexed with a Non-selective Inhibitor, Flurbiprofen
18. 3ntg: Crystal Structure of Cox-2 with Selective Compound 23d-(r)
19. 3ntb: Structure of 6-methylthio Naproxen Analog Bound to Mcox-2.
20. 3nt1: High Resolution Structure of Naproxen:cox-2 Complex.
21. 3n8z: Crystal Structure of Cyclooxygenase-1 in Complex with Flurbiprofen
22. 3n8y: Structure of Aspirin Acetylated Cyclooxygenase-1 in Complex with Diclofenac
23. 3n8x: Crystal Structure of Cyclooxygenase-1 in Complex with Nimesulide
24. 3n8w: Crystal Structure of R120Q/NATIVE Cyclooxygenase-1 Heterodimer Mutant in Complex with Flurbiprofen
25. 3n8v: Crystal Structure of Unoccupied Cyclooxygenase-1
26. 3mqe: Structure of Sc-75416 Bound at The Cox-2 Active Site
27. 3ln1: Structure of Celecoxib Bound at The Cox-2 Active Site
28. 3ln0: Structure of Compound 5c-s Bound at The Active Site of Cox-2
29. 3krk: X-ray Crystal Structure of Arachidonic Acid Bound in The Cyclooxygenase Channel of L531F Murine Cox-2
30. 3kk6: Crystal Structure of Cyclooxygenase-1 in Complex with Celecoxib
31. 1pge: Prostaglandin H2 Synthase-1 Complexed with P-(2'-iodo-5'- Thenoyl)hydrotropic Acid (iodosuprofen)
32. 1pgf: Prostaglandin H2 Synthase-1 Complexed with 1-(4- Iodobenzoyl)-5-methoxy-2-methylindole-3-acetic Acid (iodoindomethacin), Cis Model
33. 1pgg: Prostaglandin H2 Synthase-1 Complexed with 1-(4- Iodobenzoyl)-5-methoxy-2-methylindole-3-acetic Acid (iodoindomethacin), Trans Model
34. 1prh: The X-ray Crystal Structure of The Membrane Protein Prostaglandin H2 Synthase-1
35. 1pth: The Structural Basis of Aspirin Activity Inferred from The Crystal Structure of Inactivated Prostaglandin H2 Synthase
36. 1pxx: Crystal Structure of Diclofenac Bound to The Cyclooxygenase Active Site of Cox-2
37. 1q4g: 2.0 Angstrom Crystal Structure of Ovine Prostaglandin H2 Synthase-1, in Complex with Alpha-methyl-4-biphenylacetic Acid
38. 6v3r: Crystal Structure of Murine Cycloxygenase in Complex with a Harmaline Analog, 4,9-dihydro-3h-pyrido[3,4-b]indole
39. 3hs7: X-ray Crystal Structure of Docosahexaenoic Acid Bound to The Cyclooxygenase Channel of Cyclooxygenase-2
40. 3hs6: X-ray Crystal Structure of Eicosapentaenoic Acid Bound to The Cyclooxygenase Channel of Cyclooxygenase-2
41. 3hs5: X-ray Crystal Structure of Arachidonic Acid Bound to The Cyclooxygenase Channel of Cyclooxygenase-2
42. 6ofy: Crystal Structure of Arachidonic Acid Bound to V349I Murine Cox-2
43. 1u67: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostagladin H Synthase-1 That Forms Predominantly 11- Hpete.
44. 2ayl: 2.0 Angstrom Crystal Structure of Manganese Protoporphyrin Ix-reconstituted Ovine Prostaglandin H2 Synthase-1 Complexed with Flurbiprofen
45. 2oyu: Indomethacin-(s)-alpha-ethyl-ethanolamide Bound to Cyclooxygenase-1
46. 2oye: Indomethacin-(r)-alpha-ethyl-ethanolamide Bound to Cyclooxygenase-1
47. 6bl4: Crystal Complex of Cyclooxygenase-2 with Indomethacin-ethylenediamine- Dansyl Conjugate
48. 6bl3: Crystal Complex of Cyclooxygenase-2 with Indomethacin-butyldiamine- Dansyl Conjugate
49. 3mdl: X-ray Crystal Structure of 1-arachidonoyl Glycerol Bound to The Cyclooxygenase Channel of Cyclooxygenase-2
50. 3olt: X-ray Crystal Structure of Arachidonic Acid Bound to The Cyclooxygenase Channel of R513H Murine Cox-2
51. 3olu: X-ray Crystal Structure of 1-arachidonoyl Glycerol Bound to The Cyclooxygenase Channel of R513H Murine Cox-2
52. 3qh0: X-ray Crystal Structure of Palmitic Acid Bound to The Cyclooxygenase Channel of Cyclooxygenase-2
53. 3qmo: X-ray Crystal Structure of Ns-398 Bound to The Cyclooxygenase Channel of Cyclooxygenase-2
54. 3q7d: Structure of (r)-naproxen Bound to Mcox-2.
55. 3rr3: Structure of (r)-flurbiprofen Bound to Mcox-2
56. 3tzi: X-ray Crystal Structure of Arachidonic Acid Bound in The Cyclooxygenase Channel of G533V Murine Cox-2
57. 4e1g: X-ray Crystal Structure of Alpha-linolenic Acid Bound to The Cyclooxygenase Channel of Cyclooxygenase-2
58. 6y3c: Human Cox-1 Crystal Structure
59. 4fm5: X-ray Structure of Des-methylflurbiprofen Bound to Murine Cox-2
60. 4m10: Crystal Structure of Murine Cyclooxygenase-2 Complex with Isoxicam
61. 4m11: Crystal Structure of Murine Cyclooxygenase-2 Complex with Meloxicam
62. 4o1z: Crystal Structure of Ovine Cyclooxygenase-1 Complex with Meloxicam
63. 4oty: Crystal Structure of Lumiracoxib Bound to The Apo-mouse- Cyclooxygenase-2
64. 5wbe: Cox-1:mofezolac Complex Structure
65. 5w58: Crystal Complex of Cyclooxygenase-2: (s)-arn-2508 (a Dual Cox and Faah Inhibitor)
66. 4ph9: The Structure of Ibuprofen Bound to Cyclooxygenase-2
67. 5u6x: Cox-1:p6 Complex Structure
68. 5kir: The Structure of Vioxx Bound to Human Cox-2
69. 5jw1: Crystal Structure of Celecoxib Bound to S121P Murine Cox-2 Mutant
70. 5jvz: Crystal Structure of Flurbiprofen Bound to S121P Murine Cox-2 Mutant
71. 5jvy: Crystal Structure of S121P Murine Cox-2 Mutant
72. 5ikv: The Structure of Flufenamic Acid Bound to Human Cyclooxygenase-2
73. 5ikt: The Structure of Tolfenamic Acid Bound to Human Cyclooxygenase-2
74. 5ikr: The Structure of Mefenamic Acid Bound to Human Cyclooxygenase-2
75. 5ikq: The Structure of Meclofenamic Acid Bound to Human Cyclooxygenase-2
76. 5fdq: Murine Cox-2 S530T Mutant
77. 5f1a: The Crystal Structure of Salicylate Bound to Human Cyclooxygenase-2
78. 5f19: The Crystal Structure of Aspirin Acetylated Human Cyclooxygenase-2
79. 4rut: Crystal Structure of Murine Cyclooxygenase-2 with 13-methyl- Arachidonic Acid
80. 4z0l: The Murine Cyclooxygenase-2 Complexed with a Nido-dicarbaborate- Containing Indomethacin Derivative
81. 4otj: The Complex of Murine Cyclooxygenase-2 with a Conjugate of Indomefathin and Podophyllotoxin, N-{(succinylpodophyllotoxinyl)but- 4-yl}-2-{1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indol-3- Yl}acetamide
82. 4rrw: Crystal Structure of Apo Murine Cyclooxygenase-2
83. 4rrx: Crystal Structure of Apo Murine V89W Cyclooxygenase-2 Complexed with Lumiracoxib
84. 4rry: Crystal Structure of Apo Murine H90W Cyclooxygenase-2
85. 4rrz: Crystal Structure of Apo Murine H90W Cyclooxygenase-2 Complexed with Lumiracoxib
86. 4rs0: Crystal Structure of Murine H90W Cyclooxygenase-2 Complexed with S- Ibuprofen
87. 7jxt: Structure of The Ovine Cox-1 Bound to Compound 2a