EC 1.8.1.12 - trypanothione:NADP ⁺ oxidoreductase (trypanothione- disulfide reductase)

3D structures of EC 1.8.1.12 - trypanothione-disulfide reductase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 2wpf: Trypanosoma Brucei Trypanothione Reductase in Complex with 3,4-dihydroquinazoline Inhibitor (ddd00085762)
2. 2wpe: Trypanosoma Brucei Trypanothione Reductase in Complex with 3,4-dihydroquinazoline Inhibitor (ddd00073359)
3. 2wpc: Trypanosoma Brucei Trypanothione Reductase in Complex with 3,4-dihydroquinazoline Inhibitor (ddd00073357)
4. 2wp6: Trypanosoma Brucei Trypanothione Reductase in Complex with 3,4-dihydroquinazoline Inhibitor (ddd00071494)
5. 2wp5: Trypanosoma Brucei Trypanothione Reductase in Complex with 3,4-dihydroquinazoline Inhibitor (ddd00065414)
6. 2wow: Trypanosoma Brucei Trypanothione Reductase with Nadp and Trypanothione Bound
7. 2wov: Trypanosoma Brucei Trypanothione Reductase with Bound Nadp.
8. 2woi: Trypanothione Reductase from Trypanosoma Brucei
9. 2wba: Properties of Trypanothione Reductase from T. Brucei
10. 2w0h: X Ray Structure of Leishmania Infantum Trypanothione Reductase in Complex with Antimony and Nadph
11. 6bu7: Crystal Structure of Trypanothione Reductase from Trypanosoma Brucei in Complex with Inhibitor Rd130 1-[2-(piperidin-4-yl)ethyl]-5-{5-[1- (pyrrolidin-1-yl)cyclohexyl]-1,3-thiazol-2-yl}-1h-indole
12. 6btl: Crystal Structure of Trypanothione Reductase from Trypanosoma Brucei in Complex with Inhibitor Rd117 1-[2-(piperazin-1-yl)ethyl]-5-{5-[1- (pyrrolidin-1-yl)cyclohexyl]-1,3-thiazol-2-yl}-1h-indole
13. 2jk6: Structure of Trypanothione Reductase from Leishmania Infantum
14. 6t98: Trypanothione Reductase from Leishmania Infantum in Complex with Trl187
15. 6t97: Trypanothione Reductase from Leismania Infantum in Complex with Trl190
16. 6t95: Trypanothione Reductase from Leismania Infantum in Complex with Trl149
17. 2x50: Crystal Structure of Trypanothione Reductase from Leishmania Infantum in Complex with Nadph and Silver
18. 6rb5: Trypanothione Reductase in Complex with 4-(((3-(8-(2-((1r,2s,5r)-6,6- Dimethylbicyclo[3.1.1]heptan-2-yl)ethyl)-4-oxo-1-phenyl-1,3,8- Triazaspiro[4.5]decan-3-yl)propyl)(methyl)amino)methyl)-4- Hydroxypiperidine-1-carboximidamide
19. 2yau: X-ray Structure of The Leishmania Infantum Tryopanothione Reductase in Complex with Auranofin
20. 6oez: Crystal Structure of Trypanothione Reductase from Trypanosoma Brucei in Complex with Inhibitor (+)-n-(cyclobutylmethyl)-3-{5-[1- (pyrrolidin-1-yl)cyclohexyl]-2-(1-{[(2s)-pyrro-lidin-2-yl]methyl}-1h- Indol-5-yl)-1,3-thiazol-4-yl}prop-2-yn-1-amine
21. 6oey: Crystal Structure of Trypanothione Reductase from Trypanosoma Brucei in Complex with Inhibitor (+)-5-{5-[1-(pyrrolidin-1-yl)cyclohexyl]-1, 3-thiazol-2-yl}-1-{[(2s)-pyrrolidin-2-yl]methyl}-1h-indole
22. 6oex: Crystal Structure of Trypanothione Reductase from Trypanosoma Brucei in Complex with Inhibitor 3-(2-{1-[2-(piperidin-4-yl)ethyl]-1h-indol- 5-yl}-5-[1-(pyrrolidin-1-yl)cyclohexyl]-1,3- Thiazol-4-yl)-n-(2,2,2- Trifluoroethyl)prop-2-yn-1-amine
23. 6i7n: Trypanothione Reductase from Leismania Infantum in Complex with Trl156
24. 4adw: Crystal Structure of Leishmania Infantum Trypanothione Reductase in Complex with Nadph and Trypanothione
25. 4apn: Structure of Tr from Leishmania Infantum in Complex with a Diarylpirrole-based Inhibitor
26. 6er5: X-ray Structure of Trypanothione Reductase from Leishmania Infantum in Complex with 2-(diethylamino)ethyl 4-((3-(4-nitrophenyl)-3- Oxopropyl)amino)benzoate
27. 4nev: Crystal Structure of Trypanothione Reductase from Trypanosoma Brucei in Complex with Inhibitor Ep127 (5-{5-[1-(pyrrolidin-1-yl) Cyclohexyl]-1,3-thiazol-2-yl}-1h-indole)
28. 5ebk: Trypanothione Reductase in Complex with 6-(sec-butoxy)-2-((3- Chlorophenyl)thio)pyrimidin-4-amine