EC 2.5.1.1 - dimethylallyl- diphosphate:isopentenyl- diphosphate dimethylallyl trans transferase (dimethylallyl trans transferase)

3D structures of EC 2.5.1.1 - dimethylallyltranstransferase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 3oac: Mint Deletion Mutant of Heterotetrameric Geranyl Pyrophosphate Synthase in Complex with Ligands
2. 3oab: Mint Deletion Mutant of Heterotetrameric Geranyl Pyrophosphate Synthase in Complex with Ligands
3. 3n6k: Human Fpps Complex with Nov_823
4. 3n5j: Human Fpps Complex with Nov_311
5. 3n5h: Human Fpps Complex with Nov_304
6. 3n49: Human Fpps Complex with Nov_292
7. 3n46: Human Fpps Complex with Nov_980 and Zoledronic Acid/mg2+
8. 3n45: Human Fpps Complex with Fbs_04 and Zoledronic Acid/mg2+
9. 3n3l: Human Fpps Complex with Fbs_03
10. 3n1w: Human Fpps Complex with Fbs_02
11. 3n1v: Human Fpps Complex with Fbs_01
12. 3lk5: Crystal Structure of Putative Geranylgeranyl Pyrophosphate Synthase from Corynebacterium Glutamicum
13. 3krp: Mint Heterotetrameric Geranyl Pyrophosphate Synthase in Complex with Magnesium and Gpp
14. 3kro: Mint Heterotetrameric Geranyl Pyrophosphate Synthase in Complex with Magnesium, Ipp, and Dmaspp (ii)
15. 3krf: Mint Heterotetrameric Geranyl Pyrophosphate Synthase in Complex with Magnesium, Ipp, and Dmaspp (i)
16. 3krc: Mint Heterotetrameric Geranyl Pyrophosphate Synthase in Complex with Ipp
17. 3kra: Mint Heterotetrameric Geranyl Pyrophosphate Synthase in Complex with Magnesium
18. 1r9c: Crystal Structure of Fosfomycin Resistance Protein Fosx from Mesorhizobium Loti
19. 1ubv: Structure of Farnesyl Pyrophosphate Synthetase
20. 1ubw: Structure of Farnesyl Pyrophosphate Synthetase
21. 1ubx: Structure of Farnesyl Pyrophosphate Synthetase
22. 1uby: Structure of Farnesyl Pyrophosphate Synthetase
23. 3cp6: Crystal Structure of Human Farnesyl Diphosphate Synthase (T201A Mutant) Complexed with Mg and Biphosphonate Inhibitor
24. 2z7i: S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Inhibitor Bph-742
25. 2z7h: S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Inhibitor Bph-210
26. 2z78: S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Bph-806
27. 2z52: S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Magnesium and Bph-23
28. 2z50: S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Bph-28
29. 2z4z: S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Magnesium and Bph-sc01
30. 2z4y: S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Magnesium and Bph-252
31. 2z4x: S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Magnesium and Bph-252 (p21)
32. 2z4w: S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Magnesium and Bph-749
33. 2z4v: S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Magnesium and Ggpp (inhibitory Site)
34. 2vf6: Human Fdps Synthase in Complex with Minodronate
35. 2azj: Crystal Structure for The Mutant D81C of Sulfolobus Solfataricus Hexaprenyl Pyrophosphate Synthase
36. 2azk: Crystal Structure for The Mutant W136E of Sulfolobus Solfataricus Hexaprenyl Pyrophosphate Synthase
37. 2rah: Human Fdps Synthase in Complex with Novel Inhibitor
38. 2q80: Crystal Structure of Human Geranylgeranyl Pyrophosphate Synthase Bound to Ggpp
39. 6c57: Crystal Structure of Mutant Human Geranylgeranyl Pyrophosphate Synthase (Y246D) in Complex with Bisphosphonate Inhibitor Fv0109
40. 6c56: Crystal Structure of Mutant Human Geranylgeranyl Pyrophosphate Synthase (Y246D) in Its Apo Form
41. 2f7m: Crystal Structure of Unliganded Human Fpps
42. 2f89: Crystal Structure of Human Fpps in Complex with Pamidronate
43. 2f8c: Crystal Structure of Fpps in Complex with Zoledronate
44. 2f8z: Crystal Structure of Human Fpps in Complex with Zoledronate and Isopentenyl Diphosphate
45. 2f92: Crystal Structure of Human Fpps in Complex with Alendronate
46. 2f94: Crystal Structure of Human Fpps in Complex with Ibandronate
47. 2f9k: Crystal Structure of Human Fpps in Complex with Zoledronate and Zn2+
48. 6ww1: Crystal Structure of The Lmfpps Mutant E97Y
49. 6w7i: Lmfpps Mutant T164W in Complex with 476a, Ipp & Ca
50. 6vjc: Lmfpps Mutant T164Y in Complex with 476a, Ipp & Ca
51. 3qkc: Crystal Structure of Geranyl Diphosphate Synthase Small Subunit from Antirrhinum Majus
52. 3qqv: Crystal Structure of Geranylgeranyl Pyrophosphate Synthase from Corynebacterium Glutamicum Complexed with Isoprenyl Diphosphate and Magnesium
53. 3rye: Human Fdps Synthase in Complex with a N-methyl Pyridinum Bisphosphonate
54. 3s4j: Human Fdps Synthase in Complex with a Rigid Analog of Risedronate
55. 6r4v: Crystal Structure of Human Geranylgeranyl Diphosphate Synthase Bound to Ibandronate
56. 6oah: Crystal Structure of Human Fpps in Complex with an Allosteric Inhibitor Yf-02-78
57. 6oag: Crystal Structure of Human Fpps in Complex with an Allosteric Inhibitor Yf-02-82
58. 4dem: Crystal Structure of Human Fpps in Complex with Ys_04_70
59. 6n83: Crystal Structure of Human Fpps in Complex with an Allosteric Inhibitor Yf-02037
60. 6n82: Crystal Structure of Human Fpps in Complex with an Allosteric Inhibitor Yf-02037
61. 6n7z: Crystal Structure of Human Fpps in Complex with an Allosteric Inhibitor Yf-02037
62. 6n7y: Crystal Structure of Human Fpps in Complex with an Allosteric Inhibitor Mit-01-102
63. 4h5c: Crystal Structure of Human Fpps in Ternary Complex with Ys0470 and Inorganic Phosphate
64. 4h5d: Crystal Structure of Human Fpps in Ternary Complex with Ys0470 and Inorganic Pyrophosphate
65. 4h5e: Crystal Structure of Human Fpps in Ternary Complex with Ys0470 and Isopentenyl Pyrophosphate
66. 4ga3: Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with Bph-1260
67. 6g32: Crystal Structure of Human Geranylgeranyl Diphosphate Synthase Mutant D188Y
68. 6g31: Crystal Structure of Human Geranylgeranyl Diphosphate Synthase Mutant D188Y Bound to Zoledronate
69. 4kk2: Crystal Structure of a Chimeric Fpp/gfpp Synthase (target Efi-502313c) from Artemisia Spiciformis (1-72:gi751454468,73-346:gi75233326), Apo Structure
70. 4jvj: Crystal Structure of Human Fpps in Complex with Magnesium, Cl01131, and Sulfate
71. 4jzb: Crystal Structure of Leshmaniasis Major Farnesyl Diphosphate Synthase in Complex with 1-(2-hydroxy-2,2-diphosphonoethyl)-3- Phenylpyridinium, Ipp and Ca2+
72. 4jzx: Crystal Structure of Leshmaniasis Major Farnesyl Diphosphate Synthase in Complex with 3-butyl-1-(2,2-diphosphonoethyl)pyridinium, Ipp and Ca2+
73. 4k10: Crystal Structure of Leshmaniasis Major Farnesyl Diphosphate Synthase in Complex with 3-fluoro-1-(2-hydroxy-2,2-diphosphonoethyl)pyridinium and Mg2+
74. 4kfa: Crystal Structure of Human Farnesyl Pyrophosphate Synthase (T201A Mutant) Complexed with Mg and Zoledronate
75. 4kpd: Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate
76. 4kpj: Crystal Structure of Farnesyl Pyrophosphate Synthase (Y204A) Mutant Complexed with Mg, Pamidronate
77. 4kq5: Crystal Structure of Human Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg and Zoledronate
78. 4kqs: Crystal Structure of Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate
79. 4kqu: Crystal Structure of Farnesyl Synthase Mutant (Y204A) Complexed with Mg, Alendronate and Isopentenyl Pyrophosphate
80. 4l2x: Crystal Structure of Human Fpps in Complex with Magnesium, Cl02134, and Inorganic Pyrophosphate
81. 4lfv: Crystal Structure of Human Fpps in Complex with Ys0470 and Two Molecules of Inorganic Phosphate
82. 4lpg: Crystal Structure of Human Fpps in Complex with Cl01131
83. 4lph: Crystal Structure of Human Fpps in Complex with Cl03093
84. 4n9u: The Role of Lysine 200 in The Human Farnesyl Pyrophosphate Synthase Catalytic Mechanism and The Mode of Inhibition by The Nitrogen- Containing Bisphosphonates
85. 4ng6: The Effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (fpps) Mutations on The Catalytic Activity, Crystal Structure and Inhibition by Nitrogen Containing Bisphosphonates
86. 4nke: The Effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (fpps) Mutations on The Catalytic Activity, Crystal Structure and Inhibition by Nitrogen Containing Bisphosphonates
87. 4nkf: The Effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (fpps) Mutations on The Catalytic Activity, Crystal Structure and Inhibition by Nitrogen Containing Bisphosphonates
88. 4nua: The Effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (fpps) Mutations on The Catalytic Activity, Crystal Structure and Inhibition by Nitrogen Containing Bisphosphonates
89. 4p0v: Crystal Structure of Human Farnesyl Diphosphoate Synthase in Complex with Zoledronate and Taxodione
90. 4p0w: Human Farnesyl Diphosphate Synthase in Complex with Arenarone and Zoledronate
91. 4p0x: Human Farnesyl Diphosphate Synthase in Complex with Taxodione
92. 5ygi: Crystal Structure of Human Fpps in Complex with an Inhibitor Thz93
93. 4n1z: Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with Bph-1222
94. 5ksx: Crystal Structure of Human Fpps in Complex with an Allosteric Inhibitor Am-02-072
95. 5jv2: Crystal Structure of Human Fpps in Complex with an Allosteric Inhibitor Mit-01-055
96. 5jv1: Crystal Structure of Human Fpps in Complex with an Allosteric Inhibitor Cl-08-066
97. 5jv0: Crystal Structure of Human Fpps in Complex with an Allosteric Inhibitor Cl-08-038
98. 5juz: Crystal Structure of Human Fpps in Complex with an Allosteric Inhibitor Cl-06-057
99. 5ja0: Crystal Structure of Human Fpps with Allosterically Bound Fpp
100. 5h9d: Crystal Structure of Heptaprenyl Diphosphate Synthase from Staphylococcus Aureus
101. 5e8l: Crystal Structure of Geranylgeranyl Pyrophosphate Synthase 11 from Arabidopsis Thaliana
102. 5e8k: Crystal Structure of Polyprenyl Pyrophosphate Synthase 2 from Arabidopsis Thaliana
103. 5e8h: Crystal Structure of Geranylfarnesyl Pyrophosphate Synthases 2 from Arabidopsis Thaliana
104. 5djv: Crystal Structure of Human Fpps in Complex with Biaryl Compound 8e
105. 5djr: Crystal Structure of Human Fpps in Complex with Biaryl Compound 6
106. 5djp: Crystal Structure of Human Fpps in Complex with Biaryl Compound 5
107. 5diq: Crystal Structure of Human Fpps in Complex with Salicylic Acid Derivative 3a
108. 5dgs: Crystal Structure of Human Fpps in Complex with The Monophosphonate Compound 15
109. 5dgn: Crystal Structure of Human Fpps in Complex with Compound 13
110. 5dgm: Crystal Structure of Human Fpps in Complex with Monophosphonate Compound 7
111. 5cg6: Neutron Crystal Structure of Human Farnesyl Pyrophosphate Synthase in Complex with Risedronate and Isopentenyl Pyrophosphate
112. 5cg5: Neutron Crystal Structure of Human Farnesyl Pyrophosphate Synthase in Complex with Risedronate
113. 4nfi: Crystal Structure of Human Fpps in Complex with Magnesium and Jds05120
114. 4nfj: Crystal Structure of Human Fpps in Complex with Magnesium, Jds05120, and Sulfate
115. 4nfk: Crystal Structure of Human Fpps in Complex with Nickel, Jds05120, and Sulfate
116. 4ogu: The Effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (fpps) Mutations on The Catalytic Activity, Crystal Structure and Inhibition by Nitrogen Containing Bisphosphonates
117. 4qxs: Crystal Structure of Human Fpps in Complex with Wc01088
118. 4q23: The Role of Threonine 201 and Tyrosine 204 in The Human Farnesyl Pyrophosphate Synthase Catalytic Mechanism and The Mode of Inhibition by The Nitrogen-containing Bisphosphonates
119. 4pvx: Crystal Structure of Human Fpps in Complex with [({4-[4- (cyclopropyloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic Acid)
120. 4pvy: Crystal Structure of Human Fpps in Complex with [({5-[4-(propan-2- Yloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic Acid)
121. 4rxa: Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with Bph-1358
122. 4qpf: New Lower Bone Affinity Bisphosphonate Drug Design for Effective Use in Diseases Characterized by Abnormal Bone Resorption
123. 4xqr: Crystal Structure of Unliganded Human Fpps at 2.15 Angstrom Resolution
124. 4xqs: Crystal Structure of Human Fpps in Complex with One Magnesium Ion
125. 4xqt: Crystal Structure of Human Fpps in Complex with Three Magnesium Ions