EC 2.5.1.21 - farnesyl- diphosphate:farnesyl- diphosphate farnesyltransferase (squalene synthase)

3D structures of EC 2.5.1.21 - squalene synthase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1d8d: Co-crystal Structure of Rat Protein Farnesyltransferase Complexed with a K-RAS4B Peptide Substrate and Fpp Analog at 2.0a Resolution
2. 1d8e: Zinc-depleted Ftase Complexed with K-RAS4B Peptide Substrate and Fpp Analog.
3. 1ezf: Crystal Structure of Human Squalene Synthase
4. 1kzo: Protein Farnesyltransferase Complexed with Farnesylated K- RAS4B Peptide Product and Farnesyl Diphosphate Substrate Bound Simultaneously
5. 1kzp: Protein Farnesyltransferase Complexed with a Farnesylated K- RAS4B Peptide Product
6. 3lee: Crystal Structure of The Human Squalene Synthase Complexed with Bph- 652
7. 3asx: Human Squalene Synthase in Complex with 1-{4-[{4-chloro-2-[(2- Chlorophenyl)(hydroxy)methyl]phenyl}(2,2-dimethylpropyl)amino]-4- Oxobutanoyl}piperidine-3-carboxylic Acid
8. 3q2z: Human Squalene Synthase in Complex with N-[(3r,5s)-7-chloro-5-(2,3- Dimethoxyphenyl)-1-neopentyl-2-oxo-1,2,3,5-tetrahydro-4,1- Benzoxazepine-3-acetyl]-l-aspartic Acid
9. 3q30: Human Squalene Synthase in Complex with (2r,3r)-2-carboxymethoxy-3-[5- (2-naphthalenyl)pentyl]aminocarbonyl-3-[5-(2-naphthalenyl) Pentyloxy]propionic Acid
10. 3vj8: Crystal Structure of The Human Squalene Synthase
11. 3vj9: Crystal Structure of The Human Squalene Synthase
12. 3vja: Crystal Structure of The Human Squalene Synthase
13. 3vjb: Crystal Structure of The Human Squalene Synthase
14. 3vjc: Crystal Structure of The Human Squalene Synthase in Complex with Zaragozic Acid a
15. 3v66: Human Squalene Synthase in Complex with 2-(1-{2-[(4r,6s)-8-chloro-6- (2,3-dimethoxyphenyl)-4h,6h-pyrrolo[1,2-a][4,1]benzoxazepin-4- Yl]acetyl}-4-piperidinyl)acetic Acid
16. 3wc9: The Complex Structure of Hssqs Wtih Ligand, Fspp
17. 3wca: The Complex Structure of Tcsqs with Ligand, Fspp
18. 3wcb: The Complex Structure of Tcsqs with Ligand, Bph1237
19. 3wcc: The Complex Structure of Tcsqs with Ligand, E5700
20. 3wcd: The Complex Structure of Hssqs Wtih Ligand, Wc-9
21. 3wce: The Complex Structure of Tcsqs with Ligand, Er119884
22. 3wcf: The Complex Structure of Hssqs Wtih Ligand,bph1218
23. 3wcg: The Complex Structure of Tcsqs with Ligand, Bph1344
24. 3wch: The Complex Structure of Hssqs Wtih Ligand Bph1237
25. 3wci: The Complex Structure of Hssqs Wtih Ligand,bph1325
26. 3wcj: The Complex Structure of Hssqs Wtih Ligand,e5700
27. 3wcl: The Complex Structure of Hssqs Wtih Ligand,bph1344
28. 3wcm: The Complex Structure of Hssqs Wtih Ligand, Er119884
29. 3wef: Crystal Structure of The Human Squalene Synthase in Complex with Farnesyl Thiopyrophosphate
30. 3weg: Crystal Structure of The Human Squalene Synthase in Complex with Farnesyl Thiopyrophosphate and Magnesium Ion
31. 3weh: Crystal Structure of The Human Squalene Synthase in Complex with Presqualene Pyrophosphate
32. 3wei: Crystal Structure of The Human Squalene Synthase Y73A Mutant in Complex with Presqualene Pyrophosphate
33. 3wej: Crystal Structure of The Human Squalene Synthase F288A Mutant in Complex with Presqualene Pyrophosphate
34. 3wek: Crystal Structure of The Human Squalene Synthase F288L Mutant in Complex with Presqualene Pyrophosphate
35. 4okm: Selinadiene Synthase Apo and in Complex with Diphosphate
36. 4okz: Selinadiene Synthase in Complex with Dihydrofarnesyl Pyrophosphate
37. 3wsa: The Tuberculosis Drug Sq109 Inhibits Trypanosoma Cruzi Cell Proliferation and Acts Synergistically with Posaconazole
38. 3wsb: The Tuberculosis Drug Sq109 Inhibits Trypanosoma Cruzi Cell Proliferation and Acts Synergistically with Posaconazole