EC 2.5.1.59 - geranylgeranyl- diphosphate:protein- cysteine geranyltransferase (protein geranylgeranyltransferase type I)

3D structures of EC 2.5.1.59 - protein geranylgeranyltransferase type I in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1n4p: Protein Geranylgeranyltransferase Type-i Complexed with Geranylgeranyl Diphosphate
2. 1n4q: Protein Geranylgeranyltransferase Type-i Complexed with a Ggpp Analog and a Kkksktkcvil Peptide
3. 1n4r: Protein Geranylgeranyltransferase Type-i Complexed with a Geranylgeranylated Kkksktkcvil Peptide Product
4. 1n4s: Protein Geranylgeranyltransferase Type-i Complexed with Ggpp and a Geranylgeranylated Kkksktkcvil Peptide Product
5. 1s63: Human Protein Farnesyltransferase Complexed with L-778,123 and Fpp
6. 1s64: Rat Protein Geranylgeranyltransferase Type-i Complexed with L-778,123 and a Sulfate Anion
7. 1sa4: Human Protein Farnesyltransferase Complexed with Fpp and R115777
8. 1sa5: Rat Protein Farnesyltransferase Complexed with Fpp and Bms- 214662
9. 3euv: Crystal Structure of Ftase(alpha-subunit; Beta-subunit Delta C10, W102T, Y154T) in Complex with Biotingpp
10. 3eu5: Crystal Structure of Ftase(alpha-subunit; Beta-subunit Delta C10) in Complex with Biotingpp
11. 1tnb: Rat Protein Geranylgeranyltransferase Type-i Complexed with a Ggpp Analog and a Substrate Kksktkcvif Peptide Derived from Tc21
12. 1tno: Rat Protein Geranylgeranyltransferase Type-i Complexed with a Ggpp Analog and a Kkksktkcvim Peptide Derived from K- RAS4B
13. 1tnu: Rat Protein Geranylgeranyltransferase Type-i Complexed with a Ggpp Analog and a Gcincckvl Peptide Derived from Rhob
14. 1tny: Rat Protein Geranylgeranyltransferase Type-i Complexed with a Ggpp Analog and a Frekkffcail Peptide Derived from The Heterotrimeric G Protein Gamma-2 Subunit
15. 1tnz: Rat Protein Geranylgeranyltransferase Type-i Complexed with a Ggpp Analog and a Rrcvll Peptide Derived from Cdc42 Splice Isoform-2
16. 3e37: Protein Farnesyltransferase Complexed with Bisubstrate Ethylenediamine Scaffold Inhibitor 5
17. 3e34: Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine-scaffold Inhibitor 10
18. 3e33: Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine Scaffold Inhibitor 7
19. 3e32: Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine Scaffold Inhibitor 2
20. 3e30: Protein Farnesyltransferase Complexed with Fpp and Ethylene Diamine Inhibitor 4
21. 3dra: Candida Albicans Protein Geranylgeranyltransferase-i Complexed with Ggpp
22. 3dpy: Protein Farnesyltransferase Complexed with Fpp and Caged Tkcvim Substrate
23. 1x81: Farnesyl Transferase Structure of Jansen Compound
24. 2bed: Structure of Fpt Bound to Inhibitor Sch207736
25. 2f0y: Crystal Structure of Human Protein Farnesyltransferase Complexed with Farnesyl Diphosphate and Hydantoin Derivative
26. 2h6f: Protein Farnesyltransferase Complexed with a Farnesylated Ddptasacvls Peptide Product at 1.5a Resolution
27. 2h6g: W102T Protein Farnesyltransferase Mutant Complexed with a Geranylgeranylated Ddptasacvls Peptide Product at 1.85a Resolution
28. 2h6h: Y365F Protein Farnesyltransferase Mutant Complexed with a Farnesylated Ddptasacvls Peptide Product at 1.8a
29. 2h6i: W102T/Y365F Protein Farnesyltransferase Double Mutant Complexed with a Geranylgeranylated Ddptasacvls Peptide Product at 3.0a
30. 2iej: Human Protein Farnesyltransferase Complexed with Inhibitor Compound Stn-48 and Fpp Analog at 1.8a Resolution
31. 3pz4: Crystal Structure of Ftase(alpha-subunit; Beta-subunit Delta C10) in Complex with Bms3 and Lipid Substrate Fpp
32. 4gtm: Ftase in Complex with Bms Analogue 11
33. 4gto: Ftase in Complex with Bms Analogue 14
34. 4gtp: Ftase in Complex with Bms Analogue 16
35. 4gtq: Ftase in Complex with Bms Analogue 12
36. 4gtr: Ftase in Complex with Bms Analogue 13
37. 4ydo: Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form
38. 7rn5: Discovery of an Anion-dependent Farnesyltransferase Inhibitor from a Phenotypic Screen
39. 7rni: Discovery of an Anion-dependent Farnesyltransferase Inhibitor from a Phenotypic Screen