EC 2.5.1.58 - farnesyl- diphosphate:protein- cysteine farnesyltransferase (protein farnesyltransferase)

3D structures of EC 2.5.1.58 - protein farnesyltransferase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1n4p: Protein Geranylgeranyltransferase Type-i Complexed with Geranylgeranyl Diphosphate
2. 1n4q: Protein Geranylgeranyltransferase Type-i Complexed with a Ggpp Analog and a Kkksktkcvil Peptide
3. 1n4r: Protein Geranylgeranyltransferase Type-i Complexed with a Geranylgeranylated Kkksktkcvil Peptide Product
4. 1n4s: Protein Geranylgeranyltransferase Type-i Complexed with Ggpp and a Geranylgeranylated Kkksktkcvil Peptide Product
5. 3ksq: Discovery of C-imidazole Azaheptapyridine Fpt Inhibitors
6. 3ksl: Structure of Fpt Bound to Datfp-dh-gpp
7. 1s63: Human Protein Farnesyltransferase Complexed with L-778,123 and Fpp
8. 1s64: Rat Protein Geranylgeranyltransferase Type-i Complexed with L-778,123 and a Sulfate Anion
9. 1sa4: Human Protein Farnesyltransferase Complexed with Fpp and R115777
10. 1sa5: Rat Protein Farnesyltransferase Complexed with Fpp and Bms- 214662
11. 3euv: Crystal Structure of Ftase(alpha-subunit; Beta-subunit Delta C10, W102T, Y154T) in Complex with Biotingpp
12. 3eu5: Crystal Structure of Ftase(alpha-subunit; Beta-subunit Delta C10) in Complex with Biotingpp
13. 1tn6: Protein Farnesyltransferase Complexed with a RAP2A Peptide Substrate and a Fpp Analog at 1.8a Resolution
14. 1tn7: Protein Farnesyltransferase Complexed with a Tc21 Peptide Substrate and a Fpp Analog at 2.3a Resolution
15. 1tn8: Protein Farnesyltransferase Complexed with a H-ras Peptide Substrate and a Fpp Analog at 2.25a Resolution
16. 3e37: Protein Farnesyltransferase Complexed with Bisubstrate Ethylenediamine Scaffold Inhibitor 5
17. 3e34: Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine-scaffold Inhibitor 10
18. 3e33: Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine Scaffold Inhibitor 7
19. 3e32: Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine Scaffold Inhibitor 2
20. 3e30: Protein Farnesyltransferase Complexed with Fpp and Ethylene Diamine Inhibitor 4
21. 3dra: Candida Albicans Protein Geranylgeranyltransferase-i Complexed with Ggpp
22. 3dpy: Protein Farnesyltransferase Complexed with Fpp and Caged Tkcvim Substrate
23. 2zis: Crystal Structure of Rat Protein Farnesyltransferase Complexed with a Bezoruran Inhibitor and Fpp
24. 2zir: Crystal Structure of Rat Protein Farnesyltransferase Complexed with a Benzofuran Inhibitor and Fpp
25. 1x81: Farnesyl Transferase Structure of Jansen Compound
26. 2bed: Structure of Fpt Bound to Inhibitor Sch207736
27. 2r2l: Structure of Farnesyl Protein Transferase Bound to Pb-93
28. 2f0y: Crystal Structure of Human Protein Farnesyltransferase Complexed with Farnesyl Diphosphate and Hydantoin Derivative
29. 2h6f: Protein Farnesyltransferase Complexed with a Farnesylated Ddptasacvls Peptide Product at 1.5a Resolution
30. 2h6g: W102T Protein Farnesyltransferase Mutant Complexed with a Geranylgeranylated Ddptasacvls Peptide Product at 1.85a Resolution
31. 2h6h: Y365F Protein Farnesyltransferase Mutant Complexed with a Farnesylated Ddptasacvls Peptide Product at 1.8a
32. 2h6i: W102T/Y365F Protein Farnesyltransferase Double Mutant Complexed with a Geranylgeranylated Ddptasacvls Peptide Product at 3.0a
33. 2iej: Human Protein Farnesyltransferase Complexed with Inhibitor Compound Stn-48 and Fpp Analog at 1.8a Resolution
34. 3pz4: Crystal Structure of Ftase(alpha-subunit; Beta-subunit Delta C10) in Complex with Bms3 and Lipid Substrate Fpp
35. 4gtm: Ftase in Complex with Bms Analogue 11
36. 4gto: Ftase in Complex with Bms Analogue 14
37. 4gtp: Ftase in Complex with Bms Analogue 16
38. 4gtq: Ftase in Complex with Bms Analogue 12
39. 4gtr: Ftase in Complex with Bms Analogue 13
40. 4l9p: Crystal Structure of Aspergillus Fumigatus Protein Farnesyltransferase Complexed with The Fii Analog, Fpt-ii, and The Kcvvm Peptide
41. 4lnb: Aspergillus Fumigatus Protein Farnesyltransferase Ternary Complex with Farnesyldiphosphate and Ethylenediamine Scaffold Inhibitor 5
42. 4lng: Aspergillus Fumigatus Protein Farnesyltransferase Complex with Farnesyldiphosphate and Tipifarnib
43. 4mbg: Crystal Structure of Aspergillus Fumigatus Protein Farnesyltransferase Binary Complex with Farnesyldiphosphate
44. 4ydo: Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form
45. 7rn5: Discovery of an Anion-dependent Farnesyltransferase Inhibitor from a Phenotypic Screen
46. 7rni: Discovery of an Anion-dependent Farnesyltransferase Inhibitor from a Phenotypic Screen