EC 2.5.1.15 - (2- amino- 4- hydroxy- 7,8- dihydropteridin- 6- yl) methyl- diphosphate:4- aminobenzoate 2- amino- 4- hydroxydihydropteridine- 6- methenyltransferase (dihydropteroate synthase)

3D structures of EC 2.5.1.15 - dihydropteroate synthase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1ad1: Dihydropteroate Synthetase (apo Form) from Staphylococcus Aureus
2. 1ad4: Dihydropteroate Synthetase Complexed with Oh-ch2-pterin- Pyrophosphate from Staphylococcus Aureus
3. 1aj0: Crystal Structure of a Ternary Complex of E. Coli Dihydropteroate Synthase
4. 1aj2: Crystal Structure of a Binary Complex of E. Coli Dihydropteroate Synthase
5. 1ajz: Structure of Dihydropteroate Pyrophosphorylase
6. 1eye: 1.7 Angstrom Resolution Crystal Structure of 6- Hydroxymethyl-7,8-dihydropteroate Synthase (dhps) from Mycobacterium Tuberculosis in Complex with 6- Hydroxymethylpterin Monophosphate
7. 3h2o: Structural Studies of Pterin-based Inhibitors of Dihydropteroate Synthase
8. 3h2n: Structural Studies of Pterin-based Inhibitors of Dihydropteroate Synthase
9. 3h2m: Structural Studies of Pterin-based Inhibitors of Dihydropteroate Synthase
10. 3h2f: Structural Studies of Pterin-based Inhibitors of Dihydropteroate Synthase
11. 3h2e: Structural Studies of Pterin-based Inhibitors of Dihydropteroate Synthase
12. 3h2c: Structural Studies of Pterin-based Inhibitors of Dihydropteroate Synthase
13. 3h2a: Structural Studies of Pterin-based Inhibitors of Dihydropteroate Synthase
14. 3h26: Structural Studies of Pterin-based Inhibitors of Dihydropteroate Synthase
15. 3h24: Structural Studies of Pterin-based Inhibitors of Dihydropteroate Synthase
16. 3h23: Structural Studies of Pterin-based Inhibitors of Dihydropteroate Synthase
17. 3h22: Structural Studies of Pterin-based Inhibitors of Dihydropteroate Synthase
18. 3h21: Structural Studies of Pterin-based Inhibitors of Dihydropteroate Synthase
19. 1tws: Dihydropteroate Synthetase from Bacillus Anthracis
20. 1tww: Dihydropteroate Synthetase, with Bound Substrate Analogue Ptpp, from Bacillus Anthracis
21. 1twz: Dihydropteroate Synthetase, with Bound Substrate Analogue Ptp, from Bacillus Anthracis
22. 1tx0: Dihydropteroate Synthetase, with Bound Product Analogue Pteroic Acid, from Bacillus Anthracis
23. 1tx2: Dihydropteroate Synthetase, with Bound Inhibitor Manic, from Bacillus Anthracis
24. 2veg: Dihydropteroate Synthase from Streptococcus Pneumoniae: Complex with 6-hydroxymethyl-7,8-dihydropterin Monophosphate
25. 2vef: Dihydropteroate Synthase from Streptococcus Pneumoniae
26. 2dqw: Crystal Structure of Dihydropteroate Synthase (folp) from Thermus Thermophilus Hb8
27. 2dza: Crystal Structure of Dihydropteroate Synthase from Thermus Thermophilus Hb8 in Complex with 4-aminobenzoate
28. 2dzb: Crystal Structure of Dihydropteroate Synthase from Thermus Thermophilus Hb8 in Complex with 6hmppp
29. 5z79: Crystal Structure Analysis of The Hppk-dhps in Complex with Substrates
30. 2y5j: Crystal Structure of Burkholderia Cenocepacia Dihydropteroate Synthase.
31. 2y5s: Crystal Structure of Burkholderia Cenocepacia Dihydropteroate Synthase Complexed with 7,8-dihydropteroate.
32. 6ofw: Dihydropteroate Synthase from Xanthomonas Albilineans in Complex with 7,8-dihydropteroate
33. 6ucz: Crystal Structure of Dihydropteroate Synthase from Anaplasma Phagocytophilum with Bound 6-hydroxymethylpterin-monophosphate
34. 3tr9: Structure of a Dihydropteroate Synthase (folp) in Complex with Pteroic Acid from Coxiella Burnetii
35. 6pz2: Crystal Structure of Folp (dihydropteroate Synthase) from Colstridium Difficile in The Presence of Pteroic Acid
36. 3tya: Dihydropteroate Synthase in Complex with Product
37. 3tyb: Dihydropteroate Synthase in Complex with Phba and Dhp+
38. 3tyc: Dihydropteroate Synthase in Complex with Dhp+
39. 3tyd: Dihydropteroate Synthase in Complex with Ppi and Dhp+
40. 3tye: Dihydropteroate Synthase in Complex with Dhp-stz
41. 3tyu: Crystal Structure of Dihydropteroate Synthetase with Product1
42. 3tyz: Crystal Structure of The Yersinia Pestis Dihydropteroate Synthetase with Substrate Transition State Complex.
43. 3tzf: Crystal Structure of The Yersinia Pestis Dihydropteroate Synthase with Sulfonamide Drug Complex.
44. 3tzn: Crystal Structure of The Yersinia Pestis Dihydropteroate Synthase.
45. 6omz: Crystal Structure of Dihydropteroate Synthase from Mycobacterium Smegmatis with Bound 6-hydroxymethylpterin-monophosphate
46. 3v5o: Structural and Mechanistic Studies of Catalysis and Sulfa Drug Resistance in Dihydropteroate Synthase
47. 4d8z: Crystal Structure of B. Anthracis Dhps with Compound 24
48. 4d9p: Crystal Structure of B. Anthracis Dhps with Compound 17
49. 4dai: Crystal Structure of B. Anthracis Dhps with Compound 23
50. 4db7: Crystal Structure of B. Anthracis Dhps with Compound 25
51. 4d8a: Crystal Structure of B. Anthracis Dhps with Compound 21
52. 4daf: Crystal Structure of B. Anthracis Dhps with Compound 19
53. 4hb7: The Structure of Dihydropteroate Synthase from Staphylococcus Aureus Subsp. Aureus Mu50.
54. 6day: Xanthomonas Albilineans Dihydropteroate Synthase with 4-aminobenzoic Acid at 1.65 a
55. 6clv: Staphylococcus Aureus Dihydropteroate Synthase (sadhps) F17L E208K Double Mutant Structure
56. 6clu: Staphylococcus Aureus Dihydropteroate Synthase (sadhps) F17L E208K Double Mutant Structure
57. 4nhv: Crystal Structure of B. Anthracis Dhps with Interfacial Compound 4: 5- (trifluoromethyl)-1,2-benzoxazol-3-amine
58. 4nil: Crystal Structure of B. Anthracis Dhps with Compound 5: 4- [(trifluoromethyl)sulfanyl]benzamide
59. 4nir: Crystal Structure of B. Anthracis Dhps with Compound 6: 3-[6- (trifluoromethyl)-1h-benzimidazol-2-yl]propan-1-ol
60. 4nl1: Crystal Structure of B. Anthracis Dhps with Compound 11: (e)-n-[4- (trifluoromethyl)benzyl]-1-[4-(trifluoromethyl)phenyl]methanimine
61. 4pzv: Crystal Structure of Francisella Tularensis Hppk-dhps in Complex with Bisubstrate Analog Hppk Inhibitor J1D
62. 5v7a: E. Coli Dihydropteroate Synthase Complexed with an 8-mercaptoguanine Derivative: 2-((2-amino-9-methyl-6-oxo-6,9-dihydro-1h-purin-8-yl) Thio)acetic Acid
63. 5v79: E. Coli Dihydropteroate Synthase Complexed with an 8-mercaptoguanine Derivative: 2-((2-amino-9-methyl-6-oxo-6,9-dihydro-1h-purin-8-yl) Thio)-n-phenylacetamide
64. 6q62: Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (indole-2-carboxylic Acid) and (6-chloroguanine)
65. 5usw: The Crystal Structure of 7,8-dihydropteroate Synthase from Vibrio Fischeri Es114
66. 5umg: Crystal Structure of Dihydropteroate Synthase from Klebsiella Pneumoniae Subsp.
67. 5u14: E. Coli Dihydropteroate Synthase Complexed with an 8-mercaptoguanine Derivative: 4-{2-[(2-amino-6-oxo-6,9-dihydro-1h-purin-8-yl) Sulfanyl]ethyl}benzene-1-sulfonamide
68. 5u13: E. Coli Dihydropteroate Synthase Complexed with an 8-mercaptoguanine Derivative: 2-amino-8-{[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl}-1,7- Dihydro-6h-purin-6-one
69. 5u12: E. Coli Dihydropteroate Synthase Complexed with an 8-mercaptoguanine Derivative: 2-azanyl-8-[(2-fluorophenyl)methylsulfanyl]-1,9- Dihydropurin-6-one
70. 5u11: E. Coli Dihydropteroate Synthase Complexed with an 8-mercaptoguanine Derivative: 2-[(2-amino-6-oxo-6,9-dihydro-1h-purin-8-yl)sulfanyl]-n- Methylacetamide
71. 5u10: E. Coli Dihydropteroate Synthase Complexed with Pteroic Acid
72. 5u0z: E. Coli Dihydropteroate Synthase Complexed with an 8-mercaptoguanine Derivative
73. 5u0y: E. Coli Dihydropteroate Synthase Complexed with an 8-mercaptoguanine Derivative: [(2-amino-6-oxo-6,9-dihydro-1h-purin-8-yl)sulfanyl]acetic Acid
74. 5u0w: E. Coli Dihydropteroate Synthase Complexed with 9-methylguanine
75. 5u0v: E. Coli Dihydropteroate Synthase Complexed with 6-methylamino-5- Nitrosoisocytosine
76. 5jq9: Yersinia Pestis Dhps with Pterine-sulfa Conjugate Compound 16
77. 7l6p: Crystal Structure of Dihydropteroate Synthase from Stenotrophomonas Maltophilia with Active Site-bound Imidazole
78. 7mpy: Crystal Structure of Cytosolic Hppk-dhps from A.thaliana