EC 1.5.1.33 - 5,6,7,8- tetrahydrobiopterin:NADP ⁺ oxidoreductase (pteridine reductase)

3D structures of EC 1.5.1.33 - pteridine reductase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 3mcv: Structure of Ptr1 from Trypanosoma Brucei in Ternary Complex with 2,4- Diamino-5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]-pyrimidine and Nadp+
2. 3jqg: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor (nadp+) and Inhibitor 6-[(4-methoxybenzyl)sulfanyl]pyrimidine-2,4- Diamine (ax6)
3. 3jqf: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor (nadp+) and Inhibitor 1,3,5-triazine-2,4,6-triamine (ax2)
4. 3jqe: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor (nadp+) and Inhibitor 2-amino-6-(4-methoxyphenyl)-4-oxo-4,7- Dihydro-3h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (dx8)
5. 3jqd: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor (nadp+) and Inhibitor 2-amino-4-oxo-6-phenyl-4,7-dihydro-3h- Pyrrolo[2,3-d]pyrimidine-5-carbonitrile (dx7)
6. 3jqc: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor (nadp+) and Inhibitor 2-amino-6-bromo-4-oxo-4,7-dihydro-3h- Pyrrolo[2,3-d]pyrimidine-5-carbonitrile (ju2)
7. 3jqb: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor (nadp+) and Inhibitor 2-amino-5-(2-phenylethyl)-3,7-dihydro-4h- Pyrrolo[2,3-d]pyrimidin-4-one (dx6)
8. 3jqa: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor (nadp+) and Inhibitor 2-amino-1,9-dihydro-6h-purine-6-thione (dx4)
9. 3jq9: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor (nadp+) and Inhibitor 2-amino-6-(1,3-benzodioxol-5-yl)-4-oxo-4,7- Dihydro-3h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (ax1)
10. 3jq8: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor (nadp+) and Inhibitor 6,7,7-trimethyl-7,8-dihydropteridine-2,4- Diamine (dx3)
11. 3jq7: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor (nadp+) and Inhibitor 6-phenylpteridine-2,4,7-triamine (dx2)
12. 3jq6: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor (nadp+) and Inhibitor 6,7-bis(1-methylethyl)pteridine-2,4-diamine (dx1)
13. 3h4v: Selective Screening and Design to Identify Inhibitors of Leishmania Major Pteridine Reductase 1
14. 1w0c: Inhibition of Leishmania Major Pteridine Reductase (ptr1) by 2,4,6-triaminoquinazoline; Structure of The Nadp Ternary Complex.
15. 2x9v: High Resolution Structure of Tbptr1 with Trimetrexate
16. 2x9n: High Resolution Structure of Tbptr1 in Complex with Cyromazine
17. 2x9g: High Resolution Structure of Tbptr1 in Complex with Pemetrexed
18. 2wd8: Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Complex with Nadp and Ddd00071204
19. 2wd7: Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Complex with Nadp and Ddd00066750
20. 2vz0: Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Complex with Nadp and Ddd00066641
21. 2bf7: Leishmania Major Pteridine Reductase 1 in Complex with Nadp and Biopterin
22. 2bfa: Leishmania Major Pteridine Reductase 1 in Complex with Nadp and Cb3717
23. 2bfm: Leishmania Major Pteridine Reductase 1 in Complex with Nadp and Trimethoprim
24. 2bfo: Leishmania Major Pteridine Reductase 1 in Complex with Nadph
25. 2bfp: Leishmania Major Pteridine Reductase 1 in Complex with Nadp and Tetrahydrobiopterin
26. 2c7v: Structure of Trypanosoma Brucei Pteridine Reductase (ptr1) in Ternary Complex with Cofactor and The Antifolate Methotrexate
27. 2qhx: Structure of Pteridine Reductase from Leishmania Major Complexed with a Ligand
28. 6rxc: Leishmania Major Pteridine Reductase 1 (lmptr1) in Complex with Inhibitor 4 (nmt-c0026)
29. 2xox: Crystal Structure of Pteridine Reductase (ptr1) from Leishmania Donovani
30. 2yhi: Trypanosoma Brucei Ptr1 in Complex with Inhibitor Wh16
31. 2yhu: Trypanosoma Brucei Ptr1 in Complex with Inhibitor Whf30
32. 5l4n: Leishmania Major Pteridine Reductase 1 (ptr1) in Complex with Compound 1
33. 5l42: Leishmania Major Pteridine Reductase 1 (ptr1) in Complex with Compound 3
34. 5izc: Trypanosoma Brucei Ptr1 in Complex with Inhibitor F032
35. 4cl8: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
36. 4cld: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
37. 4cle: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
38. 4clh: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
39. 4clo: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
40. 4clr: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
41. 4clx: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
42. 4cm1: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
43. 4cm3: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
44. 4cm4: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
45. 4cm5: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
46. 4cm6: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
47. 4cm7: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
48. 4cm8: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
49. 4cm9: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
50. 4cma: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
51. 4cmb: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
52. 4cmc: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
53. 4cme: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
54. 4cmg: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
55. 4cmi: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
56. 4cmj: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor
57. 4cmk: Crystal Structure of Pteridine Reductase 1 (ptr1) from Trypanosoma Brucei in Ternary Complex with Cofactor and Inhibitor