EC 1.1.1.1 - alcohol:NAD ⁺ oxidoreductase (alcohol dehydrogenase)

3D structures of EC 1.1.1.1 - alcohol dehydrogenase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 1a4u: Alcohol Dehydrogenase from Drosophila Lebanonensis
2. 1a71: Ternary Complex of an Active Site Double Mutant of Horse Liver Alcohol Dehydrogenase, Phe93=>trp, Val203=>ala with Nad and Trifluoroethanol
3. 1a72: An Active-site Double Mutant (phe93->trp, Val203->ala) of Horse Liver Alcohol Dehydrogenase in Complex with The Isosteric Nad Analog Cpad
4. 1adb: Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes
5. 1adc: Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes
6. 1adf: Crystallographic Studies of Two Alcohol Dehydrogenase-bound Analogs of Thiazole-4-carboxamide Adenine Dinucleotide (tad), The Active Anabolite of The Antitumor Agent Tiazofurin
7. 1adg: Crystallographic Studies of Two Alcohol Dehydrogenase-bound Analogs of Thiazole-4-carboxamide Adenine Dinucleotide (tad), The Active Anabolite of The Antitumor Agent Tiazofurin
8. 1agn: X-ray Structure of Human Sigma Alcohol Dehydrogenase
9. 1axe: Crystal Structure of The Active-site Mutant Phe93->trp of Horse Liver Alcohol Dehydrogenase in Complex with Nad and Inhibitor Trifluoroethanol
10. 1axg: Crystal Structure of The Val203->ala Mutant of Liver Alcohol Dehydrogenase Complexed with Cofactor Nad and Inhibitor Trifluoroethanol Solved to 2.5 Angstrom Resolution
11. 1b14: Alcohol Dehydrogenase from Drosophila Lebanonensis Binary Complex with Nad+
12. 1b15: Alcohol Dehydrogenase from Drosophila Lebanonensis Ternary Complex with Nad-acetone
13. 1b16: Alcohol Dehydrogenase from Drosophila Lebanonensis Ternary Complex with Nad-3-pentanone
14. 1b2l: Alcohol Dehydrogenase from Drosophila Lebanonensis: Ternary Complex with Nad-cyclohexanone
15. 1bto: Horse Liver Alcohol Dehydrogenase Complexed to Nadh and (1s, 3r)3-butylthiolane 1-oxide
16. 1cdo: Alcohol Dehydrogenase (e.c.1.1.1.1) (ee Isozyme) Complexed with Nicotinamide Adenine Dinucleotide (nad), and Zinc
17. 1d1s: Wild-type Human Sigma (class Iv) Alcohol Dehydrogenase
18. 1d1t: Mutant of Human Sigma Alcohol Dehydrogenase with Leucine at Position 141
19. 1deh: Crystallization of Human Beta1 Alcohol Dehydrogenase (15 Mg/ml) in 50 Mm Sodium Phosphate (ph 7.5), 2.0 Mm Nad+ and 1 Mm 4-iodopyrazole at 25 Oc, 13% (w/v) Peg 8000
20. 1e3e: Mouse Class II Alcohol Dehydrogenase Complex with Nadh
21. 1e3i: Mouse Class II Alcohol Dehydrogenase Complex with Nadh and Inhibitor
22. 1e3l: P47H Mutant of Mouse Class II Alcohol Dehydrogenase Complex with Nadh
23. 1ee2: The Structure of Steroid-active Alcohol Dehydrogenase at 1.54 a Resolution
24. 1h2b: Crystal Structure of The Alcohol Dehydrogenase from The Hyperthermophilic Archaeon Aeropyrum Pernix at 1.65a Resolution
25. 1hdx: Three-dimensional Structures of Three Human Alcohol Dehydrogenase Variants: Correlations with Their Functional Differences
26. 1hdy: Three-dimensional Structures of Three Human Alcohol Dehydrogenase Variants: Correlations with Their Functional Differences
27. 1hdz: Three-dimensional Structures of Three Human Alcohol Dehydrogenase Variants: Correlations with Their Functional Differences
28. 1het: Atomic X-ray Structure of Liver Alcohol Dehydrogenase Containing a Hydroxide Adduct to Nadh
29. 1heu: Atomic X-ray Structure of Liver Alcohol Dehydrogenase Containing Cadmium and a Hydroxide Adduct to Nadh
30. 1hf3: Atomic X-ray Structure of Liver Alcohol Dehydrogenase Containing Cadmium and a Hydroxide Adduct to Nadh
31. 1hld: Structures of Horse Liver Alcohol Dehydrogenase Complexed with Nad+ and Substituted Benzyl Alcohols
32. 1hso: Human Alpha Alcohol Dehydrogenase (ADH1A)
33. 1hsz: Human Beta-1 Alcohol Dehydrogenase (ADH1B*1)
34. 1ht0: Human Gamma-2 Alcohol Dehydrogense
35. 1htb: Crystallization of Human Beta3 Alcohol Dehydrogenase (10 Mg/ml) in 100 Mm Sodium Phosphate (ph 7.5), 7.5 Mm Nad+ and 1 Mm 4-iodopyrazole at 25 C
36. 1ju9: Horse Liver Alcohol Dehydrogenase VAL292SER Mutant
37. 1jvb: Alcohol Dehydrogenase from The Archaeon Sulfolobus Solfataricus
38. 8adh: Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of The Hinge Bending Mode
39. 7adh: Three-dimensional Structure of Isonicotinimidylated Liver Alcohol Dehydrogenase
40. 6adh: Structure of Triclinic Ternary Complex of Horse Liver Alcohol Dehydrogenase at 2.9 Angstroms Resolution
41. 5adh: Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of The Hinge Bending Mode
42. 3oq6: Horse Liver Alcohol Dehydrogenase A317C Mutant Complexed with Nad+ and 2,3,4,5,6-pentafluorobenzyl Alcohol
43. 1lde: Horse Liver Alcohol Dehydrogenase Complexed to Nadh and N- Formyl Piperdine
44. 1ldy: Horse Liver Alcohol Dehydrogenase Complexed to Nadh and Cyclohexyl Formamide (cxf)
45. 1llu: The Ternary Complex of Pseudomonas Aeruginosa Alcohol Dehydrogenase with Its Coenzyme and Weak Substrate
46. 1m6h: Human Glutathione-dependent Formaldehyde Dehydrogenase
47. 1m6w: Binary Complex of Human Glutathione-dependent Formaldehyde Dehydrogenase and 12-hydroxydodecanoic Acid
48. 1ma0: Ternary Complex of Human Glutathione-dependent Formaldehyde Dehydrogenase with Nad+ and Dodecanoic Acid
49. 1mc5: Ternary Complex of Human Glutathione-dependent Formaldehyde Dehydrogenase with S-(hydroxymethyl)glutathione and Nadh
50. 1mg0: Horse Liver Alcohol Dehydrogenase Complexed with Nad+ and 2, 3-difluorobenzyl Alcohol
51. 1mg5: Crystal Structure of Drosophila Melanogaster Alcohol Dehydrogenase Complexed with Nadh and Acetate at 1.6 a
52. 1mgo: Horse Liver Alcohol Dehydrogenase PHE93ALA Mutant
53. 1mp0: Binary Complex of Human Glutathione-dependent Formaldehyde Dehydrogenase with Nad(h)
54. 1n8k: Horse Liver Alcohol Dehydrogenase VAL292THR Mutant Complexed to Nad+ and Pyrazole
55. 1n92: Horse Liver Alcohol Dehydrogenase Complexed with Nad+ and 4- Iodopyrazole
56. 1nto: N249Y Mutant of Alcohol Dehydrogenase from The Archaeon Sulfolobus Solfataricus-monoclinic Crystal Form
57. 1nvg: N249Y Mutant of The Alcohol Dehydrogenase from The Archaeon Sulfolobus Solfataricus-tetragonal Crystal Form
58. 1o2d: Crystal Structure of Alcohol Dehydrogenase, Iron-containing (tm0920) from Thermotoga Maritima at 1.30 a Resolution
59. 1p1r: Horse Liver Alcohol Dehydrogenase Complexed with Nadh and R- N-1-methylhexylformamide
60. 3jv7: Structure of Adh-a from Rhodococcus Ruber
61. 3i4c: Crystal Structure of Sulfolobus Solfataricus Adh(ssadh) Double Mutant (W95L,N249Y)
62. 3hud: The Structure of Human Beta 1 Beta 1 Alcohol Dehydrogenase: Catalytic Effects of Non-active-site Substitutions
63. 1qlh: Horse Liver Alcohol Dehydrogenase Complexed to Nad Double Mutant of Gly 293 Ala and pro 295 Thr
64. 1qlj: Horse Liver Alcohol Dehydrogenase Apo Enzyme Double Mutant of Gly 293 Ala and pro 295 Thr
65. 1qv6: Horse Liver Alcohol Dehydrogenase HIS51GLN/LYS228ARG Mutant Complexed with Nad+ and 2,4-difluorobenzyl Alcohol
66. 1qv7: Horse Liver Alcohol Dehydrogenase HIS51GLN/LYS228ARG Mutant Complexed with Nad+ and 2,3-difluorobenzyl Alcohol
67. 1r37: Alcohol Dehydrogenase from Sulfolobus Solfataricus Complexed with Nad(h) and 2-ethoxyethanol
68. 1rjw: Crystal Structure of Nad(+)-dependent Alcohol Dehydrogenase from Bacillus Stearothermophilus Strain Lld-r
69. 1sby: Alcohol Dehydrogenase from Drosophila Lebanonensis Complexed with Nad+ and 2,2,2-trifluoroethanol at 1.1 a Resolution
70. 1teh: Structure of Human Liver Chichi Alcohol Dehydrogenase (a Glutathione-dependent Formaldehyde Dehydrogenase)
71. 1u3t: Crystal Structure of Human Alcohol Dehydrogenase Alpha- Alpha Isoform Complexed with N-cyclopentyl-n- Cyclobutylformamide Determined to 2.5 Angstrom Resolution
72. 1u3u: Crystal Structure of Human Alcohol Dehydrogenase Beta-1- Beta-1 Isoform Complexed with N-benzylformamide Determined to 1.6 Angstrom Resolution
73. 1u3v: Crystal Structure of Human Alcohol Dehydrogenase Beta-1- Beta-1 Isoform Complexed with N-heptylformamide Determined to 1.65 Angstrom Resolution
74. 1u3w: Crystal Structure of Human Alcohol Dehydrogenase Gamma-2- Gamma-2 Isoform Complexed with N-1-methylheptylformamide Determined to 1.45 Angstrom Resolution
75. 3cos: Crystal Structure of Human Class II Alcohol Dehydrogenase (adh4) in Complex with Nad and Zn
76. 1vj0: Crystal Structure of Alcohol Dehydrogenase (tm0436) from Thermotoga Maritima at 2.00 a Resolution
77. 3bto: Horse Liver Alcohol Dehydrogenase Complexed to Nadh and (1s, 3s)3-butylthiolane 1-oxide
78. 2xaa: Alcohol Dehydrogenase Adh-'a' from Rhodococcus Ruber Dsm 44541 at Ph 8.5 in Complex with Nad and Butane-1,4-diol
79. 1ye3: Horse Liver Alcohol Dehydrogenase Apoenzyme
80. 7k35: Eqadh-nadh-4-methylbenzyl Alcohol, P21
81. 7jqa: Eqadh-nadh-4-bromobenzyl Alcohol, P21
82. 2oxi: Refined Crystal Structure of Cu-substituted Alcohol Dehydrogenase at 2.1 Angstroms Resolution
83. 2ohx: Refined Crystal Structure of Liver Alcohol Dehydrogenase- Nadh Complex at 1.8 Angstroms Resolution
84. 6xt2: Eqadh-nadh-heptafluorobutanol, P21
85. 6c49: Crystal Structure of Alcohol Dehydrogenase from Acinetobacter Baumannii
86. 6ahc: Cryo-em Structure of Aldehyde-alcohol Dehydrogenase Reveals a High- Order Helical Architecture Critical for Its Activity
87. 2eer: Structural Study of Project Id St2577 from Sulfolobus Tokodaii Strain7
88. 2fze: Crystal Structure of The Binary Complex of Human Glutathione-dependent Formaldehyde Dehydrogenase with Adp- Ribose
89. 2fzw: Structure of The Binary Complex of The E67L Mutant of Human Glutathione-dependent Formaldehyde Dehydrogenase with Nad(h)
90. 5yln: Zinc Dependent Alcohol Dehydrogenase 2 from Streptococcus Pneumonia - Apo Form
91. 2jhf: Structural Evidence for a Ligand Coordination Switch in Liver Alcohol Dehydrogenase
92. 2jhg: Structural Evidence for a Ligand Coordination Switch in Liver Alcohol Dehydrogenase
93. 6sci: Structure of Adhe Form 1
94. 6scg: Structure of Adhe Form 1
95. 7bvp: Adhe Spirosome in Extended Conformation
96. 6z42: The Low Resolution Structure of a Zinc-dependent Alcohol Dehydrogenase from Halomonas Elongata.
97. 3owo: Structures of Iron-dependent Alcohol Dehydrogenase 2 from Zymomonas Mobilis Zm4 with and without Nad Cofactor
98. 3ox4: Structures of Iron-dependent Alcohol Dehydrogenase 2 from Zymomonas Mobilis Zm4 Complexed with Nad Cofactor
99. 6tqm: Escherichia Coli Adhe Structure in Its Compact Conformation
100. 6tqh: Escherichia Coli Adhe Structure in Its Extended Conformation
101. 3qj5: S-nitrosoglutathione Reductase (gsnor) in Complex with N6022
102. 3pii: Crystal Structure of Mutant of Ht- Alcohol Dehydrogenase with Substrate Analogue Butyramide
103. 3uog: Crystal Structure of Putative Alcohol Dehydrogenase from Sinorhizobium Meliloti 1021
104. 6qhe: Alcohol Dehydrogenase from Arthrobacter Sp. Ts-15 in Complex with Nad+
105. 6owp: Horse Liver F93W Alcohol Dehydrogenase Complexed with Nad and Trifluoroethanol
106. 6owm: Horse Liver F93W Alcohol Dehydrogenase Complexed with Nad and Pentafluorobenzyl Alcohol
107. 6oa7: Horse Liver L57F Alcohol Dehydrogenase E Complexed with Nad and Trifluoroethanol
108. 6o91: Horse Liver L57F Alcohol Dehydrogenase Complexed with Nad and Pentafluorobenzyl Alcohol
109. 4dwv: Horse Alcohol Dehydrogenase Complexed with Nad+ and 2,3,4,5,6- Pentafluorobenzyl Alcohol
110. 4dxh: Horse Liver Alcohol Dehydrogenase Complexed with Nad+ and 2,2,2- Trifluoroethanol
111. 3rj5: Structure of Alcohol Dehydrogenase from Drosophila Lebanonesis T114V Mutant Complexed with Nad+
112. 3rj9: Structure of Alcohol Dehydrogenase from Drosophila Lebanonesis T114V Mutant Complexed with Nad+
113. 6nbb: Horse Liver Alcohol Dehydrogenase Determined Using Single-particle Cryo-em at 200 Kev
114. 4eex: Crystal Structure of Lactococcus Lactis Alcohol Dehydrogenase
115. 4eez: Crystal Structure of Lactococcus Lactis Alcohol Dehydrogenase Variant Re1
116. 6iqd: Crystal Structure of Alcohol Dehydrogenase from Geobacillus Stearothermophilus
117. 3uko: Crystal Structure of S-nitrosoglutathione Reductase from Arabidopsis Thaliana, Complex with Nadh
118. 4dl9: Crystal Structure of S-nitrosoglutathione Reductase from Tomato (solanum Lycopersicum) in Complex with Nad+
119. 4dla: Crystal Structure of S-nitrosoglutathione Reductase Apoenzyme from Tomato (solanum Lycopersicum)
120. 4dlb: Structure of S-nitrosoglutathione Reductase from Tomato (solanum Lycopersicum) Crystallized in Presence of Nadh and Glutathione
121. 4gl4: Crystal Structure of Oxidized S-nitrosoglutathione Reductase from Arabidopsis Thalina, Complex with Nadh
122. 4j6f: Crystal Structure of Putative Alcohol Dehydrogenase from Sinorhizobium Meliloti 1021, Nysgrc-target 012230
123. 4jji: Crystal Structure of S-nitrosoglutathione Reductase from Arabidopsis Thalina, Complex with Nad+
124. 4jbg: 1.75a Resolution Structure of a Thermostable Alcohol Dehydrogenase from Pyrobaculum Aerophilum
125. 4jbh: 2.2a Resolution Structure of Cobalt and Zinc Bound Thermostable Alcohol Dehydrogenase from Pyrobaculum Aerophilum
126. 4jbi: 2.35a Resolution Structure of Nadph Bound Thermostable Alcohol Dehydrogenase from Pyrobaculum Aerophilum
127. 4gkv: Structure of Escherichia Coli Adhp (ethanol-inducible Dehydrogenase) with Bound Nad
128. 6cxx: Horse Liver E267H Alcohol Dehydrogenase Complex with 3'- Dephosphocoenzyme a
129. 3wle: Crystal Structure of (r)-carbonyl Reductase from Candida Parapsilosis in Complex with Nad
130. 3wlf: Crystal Structure of (r)-carbonyl Reductase from Candida Parapsilosis in Complex with (r)-1-phenyl-1,2-ethanediol
131. 3wnq: Crystal Structure of (r)-carbonyl Reductase H49A Mutant from Candida Parapsilosis in Complex with 2-hydroxyacetophenone
132. 3zdr: Structure of The Alcohol Dehydrogenase (adh) Domain of a Bifunctional Adhe Dehydrogenase from Geobacillus Thermoglucosidasius Ncimb 11955
133. 4bmn: Apo Structure of Short-chain Alcohol Dehydrogenase from Ralstonia Sp. Dsm 6428
134. 4bms: Short Chain Alcohol Dehydrogenase from Ralstonia Sp. Dsm 6428 in Complex with Nadph
135. 4bmv: Short-chain Dehydrogenase from Sphingobium Yanoikuyae in Complex with Nadph
136. 4c4o: Structure of Carbonyl Reductase Cpcr2 from Candida Parapsilosis in Complex with Nadh
137. 4nfh: V207A Horse Liver Alcohol Dehydrogenase E Complexed with Nad and 2,3, 4,5,6-pentafluorobenzyl Alcohol
138. 4nfs: V203A Horse Liver Alcohol Dehydrogenase E Complexed with Nad and 2,2, 2-trifluoroethanol
139. 4ng5: V203A Horse Liver Alcohol Dehydrogenase E Complexed with Nad+ and 2,3, 4,5,6-pentafluorobenzyl Alcohol
140. 5vn1: Horse Liver Alcohol Dehydrogenae Complexed with Nadh (r,s)-n-1- Methylhexylformamide
141. 5vl0: Horse Liver Alcohol Dehydrogenase Complexed with Nadh and N- Benzyformamide
142. 5vkr: Horse Liver Alcohol Dehydrogenase Complexed with Adenosine-5- Diphosphoribose
143. 5vjg: Horse Liver Alcohol Dehydrogenase Complexed with 2,2'bipyridine
144. 5vj5: Horse Liver Alcohol Dehydrogenase Complexed with 1,10-phenanthroline
145. 4w6z: Yeast Alcohol Dehydrogenase I, Saccharomyces Cerevisiae Fermentative Enzyme
146. 4cpd: Alcohol Dehydrogenase Tadh from Thermus Sp. Atn1
147. 5kjf: V222I Horse Liver Alcohol Dehydrogenase Complexed with Nad+ and Trifluoroethanol
148. 5kje: F322L Horse Liver Alcohol Dehydrogenase Complexed with Nad+ and Pentafluorobenzyl Alcohol
149. 5kjc: V222I Horse Liver Alcohol Dehydrogenase Complexed with Nad+ and Pentafluorobenzyl Alcohol
150. 5kj6: V197I Horse Liver Alcohol Dehydrogenase Complexed with Nad+ and Pentafluorobenzyl Alcohol
151. 5kj1: G173A Horse Liver Alcohol Dehydrogenase Complexed with Nad+ and Pentafluorobenzyl Alcohol
152. 5kcz: Horse Liver S48T Alcohol Dehydrogenase Complexed with Nad and Trifluoroethanol
153. 5kcp: Horse Liver S48T Alcohol Dehydrogenase Complexed with Nad and Pentafluorobenzyl Alcohol
154. 5ilo: Crystal Structure of Photoreceptor Dehydrogenase from Drosophila Melanogaster
155. 5ilg: Crystal Structure of Photoreceptor Dehydrogenase from Drosophila Melanogaster
156. 5env: Yeast Alcohol Dehydrogenase with Bound Coenzyme
157. 5cdu: I220V Horse Liver Alcohol Dehydrogenase Complexed with Nad and Pyrazole
158. 5cdt: I220V Horse Liver Alcohol Dehydrogenase Complexed with Nad and Pentafluorobenzyl Alcohol
159. 5cds: I220L Horse Liver Alcohol Dehydrogenase Complexed with Nad and Pentafluorobenzyl Alcohol
160. 5cdg: I220F Horse Liver Alcohol Dehydrogenase Complexed with Nad and Pentafluorobenzyl Alcohol
161. 4rqt: Alcohol Dehydrogenase Crystal Structure
162. 4rqu: Alcohol Dehydrogenase Crystal Structure in Complex with Nad
163. 4xd2: Horse Liver Alcohol Dehydrogenase-nadh Complex
164. 4z6k: Alcohol Dehydrogenase from The Antarctic Psychrophile Moraxella Sp. Tae 123
165. 7kc2: Symmetry in Yeast Alcohol Dehydrogenase 1 -closed Form with Nadh
166. 7kcq: Symmetry in Yeast Alcohol Dehydrogenase 1 -open Form of Apoenzyme
167. 7kjy: Symmetry in Yeast Alcohol Dehydrogenase 1 - Open Form with Nadh