Enzyme classes: General information:
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EC 2.7.11.1 - ATP:protein phosphotransferase (non- specific) (non- specific serine/threonine protein kinase)
3D structures of EC 2.7.11.1 - non-specific serine/threonine protein kinase in Protein Data Bank
updated: 6 January 2022, 2:15
In total: 2648 PDB structures of EC 2.7.11.1 - non-specific serine/threonine protein kinase:
- 1e0a: Cdc42 Complexed with The Gtpase Binding Domain of P21 Activated Kinase
- 1h1w: High Resolution Crystal Structure of The Human Pdk1 Catalytic Domain
- 3p1a: Structure of Human Membrane-associated Tyrosine- and Threonine- Specific Cdc2-inhibitory Kinase Myt1 (pkmyt1)
- 3ow4: Discovery of Dihydrothieno- and Dihydrofuropyrimidines as Potent Pan Akt Inhibitors
- 3ot8: X-ray Crystal Structure of Compound 17r Bound to Human Chk1 Kinase Domain
- 3ot3: X-ray Crystal Structure of Compound 22k Bound to Human Chk1 Kinase Domain
- 3op5: Human Vaccinia-related Kinase 1
- 3omv: Crystal Structure of C-raf (raf-1)
- 3og7: B-raf Kinase V600E Oncogenic Mutant in Complex with Plx4032
- 3o96: Crystal Structure of Human Akt1 with an Allosteric Inhibitor
- 3o51: Crystal Structure of Anthranilamide 10 Bound to Auroraa
- 3o50: Crystal Structure of Benzamide 9 Bound to Auroraa
- 3ny5: Crystal Structure of The Rbd Domain of Serine/threonine-protein Kinase B-raf from Homo Sapiens. Northeast Structural Genomics Consortium Target HR4694F
- 3nrm: Imidazo[1,2-a]pyrazine-based Aurora Kinase Inhibitors
- 3nkx: Impaired Binding of 14-3-3 to Raf1 Is Linked to Noonan and Leopard Syndrome
- 3nay: Pdk1 in Complex with Inhibitor Mp6
- 3nax: Pdk1 in Complex with Inhibitor Mp7
- 3myg: Aurora a Kinase Complexed with Sch 1473759
- 3mvh: Crystal Structure of Akt-1-inhibitor Complexes
- 3mv5: Crystal Structure of Akt-1-inhibitor Complexes
- 3mop: The Ternary Death Domain Complex of Myd88, Irak4, and Irak2
- 3mn3: An Inhibited Conformation for The Protein Kinase Domain of The Saccharomyces Cerevisiae Ampk Homolog Snf1
- 1mry: Crystal Structure of an Inactive Akt2 Kinase Domain
- 3mfu: Cask-4m Cam Kinase Domain, Amppnp-mn2+
- 3mft: Cask-4m Cam Kinase Domain, Mn2+
- 3mfs: Cask-4m Cam Kinase Domain, Amppnp
- 3mfr: Cask-4m Cam Kinase Domain, Native
- 3mb7: Human Ck2 Catalytic Domain in Complex with a Difurane Derivative Inhibitor (amr)
- 3mb6: Human Ck2 Catalytic Domain in Complex with a Difurane Derivative Inhibitor (cpa)
- 3ma3: Crystal Structure of Human Proto-oncogene Serine Threonine Kinase (pim1) in Complex with a Consensus Peptide and a Naphtho-difuran Ligand
- 3m9g: Crystal Structure of The Three-pasta-domain of a Ser/thr Kinase from Staphylococcus Aureus
- 3m2w: Crystal Structure of Mapkak Kinase 2 (mk2) Complexed with a Spiroazetidine-tetracyclic Atp Site Inhibitor
- 3lm5: Crystal Structure of Human Serine/threonine Kinase 17b (STK17B) in Complex with Quercetin
- 3lm0: Crystal Structure of Human Serine/threonine Kinase 17b (STK17B)
- 3lj2: Ire1 Complexed with Jak Inhibitor I
- 3lj1: Ire1 Complexed with Cdk1/2 Inhibitor III
- 3lj0: Ire1 Complexed with Adp and Quercetin
- 3lau: Crystal Structure of Aurora2 Kinase in Complex with a GSK3BETA Inhibitor
- 3kxn: Crystal Structure of Z. Mays Ck2 Kinase Alpha Subunit in Complex with The Inhibitor Tetraiodobenzimidazole (k88)
- 3kxm: Crystal Structure of Z. Mays Ck2 Kinase Alpha Subunit in Complex with The Inhibitor K74
- 3kxh: Crystal Structure of Z. Mays Ck2 Kinase Alpha Subunit in Complex with The Inhibitor (2-dymethylammino-4,5,6,7-tetrabromobenzoimidazol-1yl- Acetic Acid (k66)
- 3kxg: Crystal Structure of Z. Mays Ck2 Kinase Alpha Subunit in Complex with The Inhibitor 3,4,5,6,7-pentabromo-1h-indazole (k64)
- 3kud: Complex of Ras-gdp with RAFRBD(A85K)
- 3kuc: Complex of RAP1A(E30D/K31E)GDP with RAFRBD(A85K/N71R)
- 1o6y: Catalytic Domain of Pknb Kinase from Mycobacterium Tuberculosis
- 3knb: Crystal Structure of The Titin C-terminus in Complex with Obscurin- like 1
- 3kn6: Crystal Structure of The C-terminal Kinase Domain of Msk1
- 3kn5: Crystal Structure of The C-terminal Kinase Domain of Msk1 in Complex with Amp-pnp
- 3khf: The Crystal Structure of The Pdz Domain of Human Microtubule Associated Serine/threonine Kinase 3 (mast3)
- 3kgv: Crystal Structure of Human Dna-dependent Protein Kinase Catalytic Subunit (dna-pkcs)
- 3kga: Crystal Structure of Mapkap Kinase 2 (mk2) Complexed with a Potent 3-aminopyrazole Atp Site Inhibitor
- 3kc3: Mk2 Complexed to Inhibitor N4-(7-(benzofuran-2-yl)-1h-indazol-5-yl) Pyrimidine-2,4-diamine
- 3ka0: Mk2 Complex with Inhibitor 6-(5-(2-aminopyrimidin-4-ylamino)-2- Hydroxyphenyl)-n-methylbenzo[b]thiophene-2-carboxamide
- 3k5u: Identification, Sar Studies and X-ray Cocrystal Analysis of a Novel Furano-pyrimidine Aurora Kinase a Inhibitor
- 3k21: Crystal Structure of Carboxy-terminus of PFC0420W.
- 3k0e: Crystal Structure of The Phosphorylation-site Mutant T426N of The Kaic Circadian Clock Protein
- 3k0c: Crystal Structure of The Phosphorylation-site Double Mutant S431A/T432E of The Kaic Circadian Clock Protein
- 3k0a: Crystal Structure of The Phosphorylation-site Mutant S431A of The Kaic Circadian Clock Protein
- 3k09: Crystal Structure of The Phosphorylation-site Mutant S431D of The Kaic Circadian Clock Protein
- 3jzm: Crystal Structure of The Phosphorylation-site Mutant T432A of The Kaic Circadian Clock Protein
- 3jya: Discovery of 3h-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors
- 3jy0: Discovery of 3h-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors
- 3jxw: Discovery of 3h-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors
- 3jvs: Characterization of The Chk1 Allosteric Inhibitor Binding Site
- 3jvr: Characterization of The Chk1 Allosteric Inhibitor Binding Site
- 3juh: Crystal Structure of a Mutant of Human Protein Kinase CK2ALPHA with Altered Cosubstrate Specificity
- 3jpv: Crystal Structure of Human Proto-oncogene Serine Threonine Kinase (pim1) in Complex with a Consensus Peptide and a Pyrrolo[2,3-a]carbazole Ligand
- 3ixe: Structural Basis of Competition between Pinch1 and Pinch2 for Binding to The Ankyrin Repeat Domain of Integrin-linked Kinase
- 3iq7: Crystal Structure of Human Haspin in Complex with 5-iodotubercidin
- 3iop: Pdk-1 in Complex with The Inhibitor Compound-8i
- 3ion: Pdk1 in Complex with Compound 8h
- 3ii5: The Complex of Wild-type B-raf with Pyrazolo Pyrimidine Inhibitor
- 3iec: Helicobacter Pylori Caga Inhibits Par1/mark Family Kinases by Mimicking Host Substrates
- 3idp: B-raf V600E Kinase Domain in Complex with an Aminoisoquinoline Inhibitor
- 3i6w: Structure and Activation Mechanism of The Chk2 Dna-damage Checkpoint Kinase
- 3i6u: Structure and Activation Mechanism of The Chk2 Dna-damage Checkpoint Kinase
- 3hyh: Crystal Structure of The Protein Kinase Domain of Yeast Amp- Activated Protein Kinase Snf1
- 3hrc: Crystal Structure of a Mutant of Human Pdk1 Kinase Domain in Complex with Atp
- 3hdn: Crystal Structure of Serum and Glucocorticoid-regulated Kinase 1 in Complex with Compound 2
- 3hdm: Crystal Structure of Serum and Glucocorticoid-regulated Kinase 1 in Complex with Compound 1
- 3ha6: Crystal Structure of Aurora a in Complex with Tpx2 and Compound 10
- 3h9o: Phosphoinositide-dependent Protein Kinase 1 (pdk-1) in Complex with Compound 9
- 3h4j: Crystal Structure of Pombe Ampk Kdaid Fragment
- 3h30: Crystal Structure of The Catalytic Subunit of Human Protein Kinase Ck2 with 5,6-dichloro-1-beta-d- Ribofuranosylbenzimidazole
- 3h10: Aurora a Inhibitor Complex
- 3h0z: Aurora a in Complex with a Bisanilinopyrimidine
- 3h0y: Aurora a in Complex with a Bisanilinopyrimidine
- 3gub: Crystal Structure of DAPKL93G Complexed with N6-(2- Phenylethyl)adenosine
- 3gu8: Crystal Structure of DAPKL93G with N6-cyclopentyladenosine
- 3gu7: Crystal Structure of DAPKQ23V-ADP-MG2+
- 3gu6: Crystal Structure of DAPKQ23V-ADP
- 3gu5: Crystal Structure of DAPKQ23V-AMPPNP-MG2+
- 3gu4: Crystal Structure of DAPKQ23V-AMPPNP
- 3gre: Crystal Structure of Saccharomyces Cerevisiae Vps15 Wd Repeat Domain
- 3gok: Binding Site Mapping of Protein Ligands
- 3ggf: Crystal Structure of Human Serine/threonine-protein Kinase Mst4 in Complex with an Quinazolin
- 3g51: Structural Diversity of The Active Conformation of The N- Terminal Kinase Domain of P90 Ribosomal S6 Kinase 2
- 3fyk: Crystal Structure of a Benzthiophene Lead Bound to Mapkap Kinase-2 (mk-2)
- 3fyj: Crystal Structure of an Optimzied Benzothiophene Inhibitor Bound to Mapkap Kinase-2 (mk-2)
- 3fy0: Crystal Structure of Pak1 Kinase Domain with Ruthenium Complex Dw1
- 3fxz: Crystal Structure of Pak1 Kinase Domain with Ruthenium Complex Lambda-fl172
- 3fxw: High Resolution Crystal Structure of Mitogen-activated Protein Kinase-activated Protein Kinase 3/inhibitor 2 Complex
- 3fwq: Inactive Conformation of Human Protein Kinase Ck2 Catalytic Subunit
- 3fpm: Crystal Structure of a Squarate Inhibitor Bound to Mapkap Kinase-2
- 3fmd: Crystal Structure of Human Haspin with an Isoquinoline Ligand
- 3fl5: Protein Kinase Ck2 in Complex with The Inhibitor Quinalizarin
- 3fhr: High Resolution Crystal Structure of Mitogen-activated Protein Kinase-activated Protein Kinase 3 (mk3)-inhibitor Complex
- 3fe3: Crystal Structure of The Kinase Mark3/par-1: T211A-S215A Double Mutant
- 3fdn: Structure-based Drug Design of Novel Aurora Kinase a Inhibitors: Structure Basis for Potency and Specificity
- 3fbv: Crystal Structure of The Oligomer Formed by The Kinase- Ribonuclease Domain of Ire1
- 3f9n: Crystal Structure of Chk1 Kinase in Complex with Inhibitor 38
- 3f6q: Crystal Structure of Integrin-linked Kinase Ankyrin Repeat Domain in Complex with Pinch1 Lim1 Domain
- 3f69: Crystal Structure of The Mycobacterium Tuberculosis Pknb Mutant Kinase Domain in Complex with Kt5720
- 3f61: Crystal Structure of M. Tuberculosis Pknb LEU33ASP/VAL222ASP Double Mutant in Complex with Adp
- 3f5u: Crystal Structure of The Death Associated Protein Kinase in Complex with Amppnp and Mg2+
- 3f5g: Crystal Structure of Death Associated Protein Kinase in Complex with Adp and Mg2+
- 3f2n: Crystal Structure of Human Haspin with an Imidazo- Pyridazine Ligand
- 3f2a: Crystal Structure of Human Pim-1 in Complex with Dappa
- 3eha: Crystal Structure of Death Associated Protein Kinase Complexed with Amppnp
- 3eh9: Crystal Structure of Death Associated Protein Kinase Complexed with Adp
- 3efw: Structure of Auroraa with Pyridyl-pyrimidine Urea Inhibitor
- 3e8d: Crystal Structures of The Kinase Domain of Akt2 in Complex with Atp-competitive Inhibitors
- 3e88: Crystal Structures of The Kinase Domain of Akt2 in Complex with Atp-competitive Inhibitors
- 3e87: Crystal Structures of The Kinase Domain of Akt2 in Complex with Atp-competitive Inhibitors
- 3e7v: Crystal Structure of Human Haspin with a Pyrazolo- Pyrimidine Ligand
- 3e5a: Crystal Structure of Aurora a in Complex with Vx-680 and Tpx2
- 3e3b: Crystal Structure of Catalytic Subunit of Human Protein Kinase CK2ALPHA Prime with a Potent Indazole-derivative Inhibitor
- 3dvl: Crystal Structure of Full Length Circadian Clock Protein Kaic with Correct Geometry at Phosphorylation Sites
- 3dlz: Crystal Structure of Human Haspin in Complex with Amp
- 3dls: Crystal Structure of Human Pas Kinase Bound to Adp
- 3dj7: Crystal Structure of The Mouse Aurora-a Catalytic Domain (asn186->gly, Lys240->arg, Met302->leu) in Complex with Compound 130.
- 3dj6: Crystal Structure of The Mouse Aurora-a Catalytic Domain (asn186->gly, Lys240->arg, Met302->leu) in Complex with Compound 823.
- 3dj5: Crystal Structure of The Mouse Aurora-a Catalytic Domain (asn186->gly, Lys240->arg, Met302->leu) in Complex with Compound 290.
- 3dgk: Crystal Structure of a Glycine-rich Loop Mutant of The Death Associated Protein Kinase Catalytic Domain
- 3dfc: Crystal Structure of a Glycine-rich Loop Mutant of The Death Associated Protein Kinase Catalytic Domain with Amppnp
- 3dcv: Crystal Structure of Human Pim1 Kinase Complexed with 4-(4- Hydroxy-3-methyl-phenyl)-6-phenylpyrimidin-2(1h)-one
- 3dak: Crystal Structure of Domain-swapped Osr1 Kinase Domain
- 3dae: Crystal Structure of Phosphorylated Snf1 Kinase Domain
- 3d9v: Crystal Structure of Rock I Bound to H-1152p a Di- Methylated Variant of Fasudil
- 3d6t: Structure of The Roc Domain from The Parkinson's Disease- Associated Leucine-rich Repeat Kinase 2 Reveals a Dimeric Gtpase
- 3d4q: Pyrazole-based Inhibitors of B-raf Kinase
- 1ul7: Solution Structure of Kinase Associated Domain 1 of Mouse Map/microtubule Affinity-regulating Kinase 3
- 3d2k: Crystal Structure of Mouse Aurora a (asn186->gly, Lys240- >arg, Met302->leu) in Complex with [7-(2-{2-[3-(3-chloro- Phenyl)-ureido]-thiazol-5-yl}-ethylamino)-pyrazolo[4,3- D]pyrimidin-1-yl]-acetic Acid
- 3d2i: Crystal Structure of Mouse Aurora a (asn186->gly, Lys240- >arg, Met302->leu) in Complex with 1-{5-[2-(1-methyl-1h- Pyrazolo[4,3-d]pyrimidin-7-ylamino)-ethyl]-thiazol-2-yl}-3- (3-trifluoromethyl-phenyl)-urea
- 1unr: Crystal Structure of The Ph Domain of Pkb Alpha in Complex with a Sulfate Molecule
- 3d15: Crystal Structure of Mouse Aurora a (asn186->gly, Lys240- >arg, Met302->leu) in Complex with 1-(3-chloro-phenyl)-3- {5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)- Ethyl]-thiazol-2- Yl}-urea [sns-314]
- 3d14: Crystal Structure of Mouse Aurora a (asn186->gly, Lys240- >arg, Met302->leu) in Complex with 1-{5-[2-(thieno[3,2- D]pyrimidin-4-ylamino)-ethyl]- Thiazol-2-yl}-3-(3- Trifluoromethyl-phenyl)-urea
- 3d0e: Crystal Structure of Human Akt2 in Complex with Gsk690693
- 3cy3: Crystal Structure of Human Proto-oncogene Serine Threonine Kinase (pim1) in Complex with a Consensus Peptide and The Jnk Inhibitor V
- 3cy2: Crystal Structure of Human Proto-oncogene Serine Threonine Kinase (pim1) in Complex with a Consensus Peptide and a Beta Carboline Ligand II
- 3cxw: Crystal Structure of Human Proto-oncogene Serine Threonine Kinase (pim1) in Complex with a Consensus Peptide and a Beta Carboline Ligand I
- 3cu8: Impaired Binding of 14-3-3 to Raf1 Is Linked to Noonan and Leopard Syndrome
- 1uwh: The Complex of Wild Type B-raf and Bay439006
- 1uwj: The Complex of Mutant V599E B-raf and Bay439006
- 3cqw: Crystal Structure of Akt-1 Complexed with Substrate Peptide and Inhibitor
- 3cqu: Crystal Structure of Akt-1 Complexed with Substrate Peptide and Inhibitor
- 3com: Crystal Structure of Mst1 Kinase
- 3coh: Crystal Structure of Aurora-a in Complex with a Pentacyclic Inhibitor
- 3ckx: Crystal Structure of Sterile 20-like Kinase 3 (mst3, Stk24) in Complex with Staurosporine
- 3ckw: Crystal Structure of Sterile 20-like Kinase 3 (mst3, Stk24)
- 3c4e: Pim-1 Kinase Domain in Complex with 3-aminophenyl-7- Azaindole
- 3c4c: B-raf Kinase in Complex with Plx4720
- 3c13: Low Ph-value Crystal Structure of Emodin in Complex with The Catalytic Subunit of Protein Kinase Ck2
- 3c0i: Cask Cam-kinase Domain- 3'-amp Complex, P212121 Form
- 3c0h: Cask Cam-kinase Domain- Amppnp Complex, P1 Form
- 3c0g: Cask Cam-kinase Domain- 3'-amp Complex, P1 Form
- 3bwf: Crystal Structure of The Human Pim1 in Complex with an Osmium Compound
- 3bqr: Crystal Structure of Human Death Associated Protein Kinase 3 (dapk3) in Complex with an Imidazo-pyridazine Ligand
- 3bqc: High Ph-value Crystal Structure of Emodin in Complex with The Catalytic Subunit of Protein Kinase Ck2
- 3bhy: Crystal Structure of Human Death Associated Protein Kinase 3 (dapk3) in Complex with a Beta-carboline Ligand
- 3bgz: Human Pim-1 Kinase in Complex with Diphenyl Indole Inhibitor Vx3
- 3bgq: Human Pim-1 Kinase in Complex with an Triazolo Pyridazine Inhibitor Vx2
- 3bgp: Human Pim-1 Complexed with a Benzoisoxazole Inhibitor Vx1
- 3beg: Crystal Structure of Sr Protein Kinase 1 Complexed to Its Substrate Asf/sf2
- 3be9: Structure-based Design and Synthesis of Novel Macrocyclic Pyrazolo[1,5-a] [1,3,5]triazine Compounds as Potent Inhibitors of Protein Kinase Ck2 and Their Anticancer Activities
- 1wak: X-ray Structure of Srpk1
- 3b43: I-band Fragment I65-i70 from Titin
- 3akl: Crystal Structure of a Helicobacter Pylori Proinflammatory Kinase Ctka
- 3akk: Crystal Structure of a Helicobacter Pylori Proinflammatory Kinase Ctka
- 3akj: Crystal Structure of a Helicobacter Pylori Proinflammatory Kinase Ctka
- 3aad: Structure of The Histone Chaperone Cia/asf1-double Bromodomain Complex Linking Histone Modifications and Site-specific Histone Eviction
- 3a99: Structure of Pim-1 Kinase Crystallized in The Presence of P27KIP1 Carboxy-terminal Peptide
- 3a62: Crystal Structure of Phosphorylated P70S6K1
- 3a61: Crystal Structure of Unphosphorylated P70S6K1 (form Ii)
- 3a60: Crystal Structure of Unphosphorylated P70S6K1 (form I)
- 3a2c: Crystal Structure of a Pyrazolopyrimidine Inhibitor Complex Bound to Mapkap Kinase-2 (mk2)
- 2zjw: Crystal Structure of Human Ck2 Alpha Complexed with Ellagic Acid
- 2zej: Structure of The Roc Domain from The Parkinson's Disease- Associated Leucine-rich Repeat Kinase 2 Reveals a Dimeric Gtpase
- 2z7s: Crystal Structure of The N-terminal Kinase Domain of Human Rsk1 Bound to Purvalnol a
- 2z7r: Crystal Structure of The N-terminal Kinase Domain of Human Rsk1 Bound to Staurosporine
- 2z7q: Crystal Structure of The N-terminal Kinase Domain of Human Rsk-1 Bound to Amp-pcp
- 2z6d: Crystal Structure of Lov1 Domain of Phototropin2 from Arabidopsis Thaliana
- 2z6c: Crystal Structure of Lov1 Domain of Phototropin1 from Arabidopsis Thaliana
- 2yza: Crystal Structure of Kinase Domain of Human 5'-amp- Activated Protein Kinase Alpha-2 Subunit Mutant (T172D)
- 2yz0: Solution Structure of Rwd/gi Domain of Saccharomyces Cerevisiae Gcn2
- 2ywp: Crystal Structure of Chk1 with a Urea Inhibitor
- 2yub: Solution Structure of The Pdz Domain from Mouse Lim Domain Kinase
- 2xru: Aurora-a T288E Complexed with Pha-828300
- 2xng: Structure of Aurora-a Bound to a Selective Imidazopyrazine Inhibitor
- 2xne: Structure of Aurora-a Bound to an Imidazopyrazine Inhibitor
- 2xkf: Structure of Nek2 Bound to Aminopyrazine Compound 2
- 2xke: Structure of Nek2 Bound to Aminipyrazine Compound 5
- 2xkd: Structure of Nek2 Bound to Aminopyrazine Compound 12
- 2xkc: Structure of Nek2 Bound to Aminopyrazine Compound 14
- 2xk8: Structure of Nek2 Bound to Aminopyrazine Compound 15
- 2xk7: Structure of Nek2 Bound to Aminopyrazine Compound 23
- 2xk6: Structure of Nek2 Bound to Aminopyrazine Compound 36
- 2xk4: Structure of Nek2 Bound to Aminopyrazine Compound 17
- 2xk3: Structure of Nek2 Bound to Aminopyrazine Compound 35
- 2xik: Structure of Human Ysk1 (yeast Sps1-ste20-related Kinase 1)
- 2xh5: Structure of 4-(4-tert-butylbenzyl)-1-(7h-pyrrolo(2,3-d) Pyrimidin-4-yl)piperidin-4-amine Bound to Pkb
- 2xf0: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2xez: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2xey: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2xck: Crystal Structure of Pdk1 in Complex with a Pyrazoloquinazoline Inhibitor
- 2xch: Crystal Structure of Pdk1 in Complex with a Pyrazoloquinazoline Inhibitor
- 2x8i: Discovery of a Novel Class of Triazolones as Checkpoint Kinase Inhibitors - Hit to Lead Exploration
- 2x8e: Discovery of a Novel Class of Triazolones as Checkpoint Kinase Inhibitors - Hit to Lead Exploration
- 2x8d: Discovery of a Novel Class of Triazolones as Checkpoint Kinase Inhibitors - Hit to Lead Exploration
- 2x81: Structure of Aurora a in Complex with Mln8054
- 2x7g: Structure of Human Serine-arginine-rich Protein-specific Kinase 2 (srpk2) Bound to Purvalanol B
- 2x7f: Crystal Structure of The Kinase Domain of Human Traf2- and Nck-interacting Kinase with WEE1CHK1 Inhibitor
- 2x6e: Aurora-a Bound to an Inhibitor
- 2x6d: Aurora-a Bound to an Inhibitor
- 2x4z: Crystal Structure of The Human P21-activated Kinase 4 in Complex with Pf-03758309
- 2x4f: The Crystal Structure of The Human Myosin Light Chain Kinase Loc340156.
- 2x39: Structure of 4-amino-n-(4-chlorobenzyl)-1-(7h-pyrrolo(2,3-d) Pyrimidin-4-yl)piperidine-4-carboxamide Bound to Pkb
- 2x18: The Crystal Structure of The Ph Domain of Human Akt3 Protein Kinase
- 2x0g: X-ray Structure of a Dap-kinase Calmodulin Complex
- 2wzj: Catalytic and Uba Domain of Kinase Mark2/(par-1) K82R, T208E Double Mutant
- 2wwm: Crystal Structure of The Titin M10-obscurin like 1 Ig Complex in Space Group P1
- 2wwk: Crystal Structure of The Titin M10-obscurin like 1 Ig F17R Mutant Complex
- 2wvi: Crystal Structure of The N-terminal Domain of Bubr1
- 2wtw: Aurora-a Inhibitor Structure (2nd Crystal Form)
- 2wtv: Aurora-a Inhibitor Structure
- 2wtk: Structure of The Heterotrimeric LKB1-STRADALPHA-MO25ALPHA Complex
- 2wtj: Crystal Structure of Chk2 in Complex with an Inhibitor
- 2wti: Crystal Structure of Chk2 in Complex with an Inhibitor
- 2wtd: Crystal Structure of Chk2 in Complex with an Inhibitor
- 2wtc: Crystal Structure of Chk2 in Complex with an Inhibitor
- 2wqo: Structure of Nek2 Bound to The Aminopyridine Cct241950
- 2wqn: Structure of Adp-bound Human Nek7
- 2wqm: Structure of Apo Human Nek7
- 2wqe: Structure of S155R Aurora-a Somatic Mutant
- 2wp3: Crystal Structure of The Titin M10-obscurin like 1 Ig Complex
- 2wnt: Crystal Structure of The Human Ribosomal Protein S6 Kinase
- 2wmx: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2wmw: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2wmv: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2wmu: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2wmt: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2wms: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2wmr: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2wmq: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2wiu: Mercury-modified Bacterial Persistence Regulator Hipba
- 2wb8: Crystal Structure of Haspin Kinase
- 2w7x: Cellular Inhibition of Checkpoint Kinase 2 and Potentiation of Cytotoxic Drugs by Novel Chk2 Inhibitor Pv1019
- 2w7r: Structure of The Pdz Domain of Human Microtubule Associated Serine-threonine Kinase 4
- 2w5h: Human Nek2 Kinase Apo
- 2w5b: Human Nek2 Kinase Atpgammas-bound
- 2w5a: Human Nek2 Kinase Adp-bound
- 2w4k: X-ray Structure of a Dap-kinase 2-302
- 2w4j: X-ray Structure of a Dap-kinase 2-277
- 2w1g: Structure Determination of Aurora Kinase in Complex with Inhibitor
- 2w1f: Structure Determination of Aurora Kinase in Complex with Inhibitor
- 2w1e: Structure Determination of Aurora Kinase in Complex with Inhibitor
- 2w1d: Structure Determination of Aurora Kinase in Complex with Inhibitor
- 2w1c: Structure Determination of Aurora Kinase in Complex with Inhibitor
- 2w0j: Crystal Structure of Chk2 in Complex with Nsc 109555, a Specific Inhibitor
- 2vwi: Structure of The Osr1 Kinase, a Hypertension Drug Target
- 2vuw: Structure of Human Haspin Kinase Domain
- 2vu3: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design.
- 2vtt: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design.
- 2vts: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design.
- 2vtr: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design.
- 2vtq: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design.
- 2vtp: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design.
- 2vto: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design.
- 2vtn: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design.
- 2vtm: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design.
- 2vtl: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design.
- 2vtj: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design.
- 2vti: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design.
- 2vth: Identification of N-(4-piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1h-pyrazole-3-carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-ray Crystallography and Structure Based Drug Design
- 2vrx: Structure of Aurora B Kinase in Complex with Zm447439
- 7atu: The Limk1 Kinase Domain Bound to Lijtf500025
- 7b6f: Gsk3-beta in Complex with Compound (s)-5c
- 7b36: Mst4 in Complex with Compound G-5555
- 7b35: Mst3 in Complex with Compound Mria13
- 7b34: Mst3 in Complex with Compound Mria12
- 7b33: Mst3 in Complex with Mria11
- 7b32: Mst3 in Complex with Mria7
- 7b31: Mst3 in Complex with Compound Mria9
- 7b30: Mst3 in Complex with Compound G-5555
- 6zxh: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State H2
- 6tlw: Human Ck2 Kinase Alpha Subunit in Complex with The Atp-competitive Inhibitor 4-bromobenzotriazole
- 6tlv: Human Ck2 Kinase Alpha Subunit in Complex with The Atp-competitive Inhibitor 5-bromobenzotriazole
- 6tls: Human Ck2 Kinase Alpha Subunit in Complex with The Atp-competitive Inhibitor 4,6-dibromobenzotriazole
- 6tlr: Human Ck2 Kinase Alpha Subunit in Complex with The Atp-competitive Inhibitor 4,7-dibromobenzotriazole
- 6tlp: Human Ck2 Kinase Alpha Subunit in Complex with The Atp-competitive Inhibitor 5,6-dibromobenzotriazole
- 6tlo: Human Ck2 Kinase Alpha Subunit in Complex with The Atp-competitive Inhibitor 4,5,6-tribromobenzotriazole
- 6tll: Human Ck2 Kinase Alpha Subunit in Complex with The Atp-competitive Inhibitor 4,5,6,7-tetrabromobenzotriazole (tbbt)
- 2vki: Structure of The Pdk1 Ph Domain K465E Mutant
- 2a38: Crystal Structure of The N-terminus of Titin
- 7jv1: Crystal Structure of Ksr1:mek1 in Complex with Amp-pnp, and Allosteric Mek Inhibitor Aps-9-95-1
- 7jv0: Crystal Structure of Ksr1:mek1 in Complex with Amp-pnp, and Allosteric Mek Inhibitor Pd0325901
- 7juz: Crystal Structure of Ksr1:mek1 in Complex with Amp-pnp, and Allosteric Mek Inhibitor Selumetinib
- 7juy: Crystal Structure of Ksr1:mek1 in Complex with Amp-pnp, and Allosteric Mek Inhibitor Cobimetinib
- 7jux: Crystal Structure of Ksr1:mek1 in Complex with Amp-pnp, and Allosteric Mek Inhibitor Trametinib
- 7juw: Crystal Structure of Ksr1:mek1 in Complex with Amp-pnp
- 7juv: Crystal Structure of Ksr2:mek1 in Complex with Amp-pnp, and Allosteric Mek Inhibitor Aps-9-95-1
- 7juu: Crystal Structure of Ksr2:mek1 in Complex with Amp-pnp, and Allosteric Mek Inhibitor Pd0325901
- 7jut: Crystal Structure of Ksr2:mek1 in Complex with Anp-pnp, and Allosteric Mek Inhibitor Selumetinib
- 7jus: Crystal Structure of Ksr2:mek1 in Complex with Amp-pnp, and Allosteric Mek Inhibitor Cobimetinib
- 7jur: Crystal Structure of Ksr2:mek1 in Complex with Amp-pnp, and Allosteric Mek Inhibitor Trametinib
- 7juq: Crystal Structure of Ksr2:mek1 in Complex with Adp
- 7jov: Crystal Structure of Rho-associated Protein Kinase 2 (rock2) in Complex with a Phenylpyrazole Amide Inhibitor
- 7jou: Crystal Structure of Rho-associated Protein Kinase 1 (rock1) in Complex with a Phenylpyrazole Amide Inhibitor
- 7jnt: Crystal Structure of Rho-associated Protein Kinase 2 (rock2) in Complex with a Potent and Selective Dual Rock Inhibitor
- 2vgp: Crystal Structure of Aurora B Kinase in Complex with a Aminothiazole Inhibitor
- 2vgo: Crystal Structure of Aurora B Kinase in Complex with Reversine Inhibitor
- 7jhp: Crystal Structure of Hras in Complex with The Ras-binding and Cysteine-rich Domains of Craf-kinase
- 2vd5: Structure of Human Myotonic Dystrophy Protein Kinase in Complex with The Bisindoylmaleide Inhibitor Bim VIII
- 2v9j: Crystal Structure of The Regulatory Fragment of Mammalian Ampk in Complexes with Mg.atp-amp
- 7c2w: Crystal Structure of Irak4 Kinase in Complex with a Small Molecule Inhibitor
- 7c2v: Crystal Structure of Irak4 Kinase in Complex with The Inhibitor Ca- 4948
- 2v92: Crystal Structure of The Regulatory Fragment of Mammalian Ampk in Complexes with Atp-amp
- 2v8q: Crystal Structure of The Regulatory Fragment of Mammalian Ampk in Complexes with Amp
- 7brc: Crystal Structure of The Tmk3 Lrr Domain
- 7avq: Crystal Structure of Haspin in Complex with Disubstituted Imidazo[1,2- B]pyridazine Inhibitor (compound 12)
- 7ats: The Limk1 Kinase Domain Bound to Lijtf500127
- 2v62: Structure of Vaccinia-related Kinase 2
- 2v55: Mechanism of Multi-site Phosphorylation from a Rock-i:rhoe Complex Structure
- 7akg: Crystal Structure of STK17B with Bound Dovitinib
- 2v3s: Structural Insights into The Recognition of Substrates and Activators by The Osr1 Kinase
- 7a4c: Crystal Structure of Human Protein Kinase CK2ALPHA (CSNK2A1 Gene Product) in Complex with The Atp-competitive Inhibitor 5,6,7- Tribromo-1h-triazolo[4,5-b]pyridine
- 7a4b: Crystal Structure of Human Protein Kinase CK2ALPHA (CSNK2A1 Gene Product) in Complex with The Atp-competitive Inhibitor 5,6-dibromo- 1h-triazolo[4,5-b]pyridine
- 7a49: Crystal Structure of Human Protein Kinase CK2ALPHA (CSNK2A1 Gene Product) in Complex with The Atp-competitive Inhibitor 6-bromo-5- Chloro-1h-triazolo[4,5-b]pyridine
- 7a2h: Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with The Atp-competitive Inhibitor 5,6,7- Tribromo-1h-imidazo[4,5-b]pyridine
- 7a22: Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with The Atp-competitive Inhibitor 5,6,7- Tribromo-1h-triazolo[4,5-b]pyridine
- 7a1z: Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with The Atp-competitive Inhibitor 6-bromo-5- Chloro-1h-triazolo[4,5-b]pyridine
- 7a1b: Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with The Atp-competitive Inhibitor 5,6-dibromo- 1h-triazolo[4,5-b]pyridine
- 6zxg: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State H1
- 6zxf: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State G
- 2uzs: A Transforming Mutation in The Pleckstrin Homology Domain of Akt1 in Cancer (AKT1-PH_E17K)
- 2uzr: A Transforming Mutation in The Pleckstrin Homology Domain of Akt1 in Cancer (AKT1-PH_E17K)
- 6zxe: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State F2
- 6zxd: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State F1
- 6zwo: Cryo-em Structure of Human Mtor Complex 2, Focused on One Half
- 6zwm: Cryo-em Structure of Human Mtor Complex 2, Overall Refinement
- 2uw9: Structure of Pkb-beta (akt2) Complexed with 4-(4-chloro- Phenyl)-4-(4-(1h-pyrazol-4-yl)-phenyl)-piperidine
- 2uvm: Structure of Pkbalpha Ph Domain in Complex with a Novel Inositol Headgroup Surrogate, Benzene 1,2,3,4- Tetrakisphosphate
- 2uv2: Crystal Structure of Human Ste20-like Kinase Bound to 4-(4-( 5-cyclopropyl-1h-pyrazol-3-ylamino)-quinazolin-2-ylamino)- Phenyl)-acetonitrile
- 2uue: Replace: a Strategy for Iterative Design of Cyclin Binding Groove Inhibitors
- 6zjf: Crystal Structure of STK17B (drak2) in Complex with Ap-229
- 6ziw: The Irak3 Pseudokinase Domain Bound to Atpgammas
- 6zhe: Cryo-em Structure of Dna-pk Dimer
- 6zha: Cryo-em Structure of Dna-pk Monomer
- 6zh8: Cryo-em Structure of Dna-pkcs:dna
- 6zh6: Cryo-em Structure of DNA-PKCS:KU80CT194
- 6zh4: Cryo-em Structure of Dna-pkcs (state 3)
- 6zh2: Cryo-em Structure of Dna-pkcs (state 1)
- 6zfp: Cryo-em Structure of Dna-pkcs (state 2)
- 2rq8: Solution Nmr Structure of Titin I27 Domain Mutant
- 2row: The C1 Domain of Rock II
- 2rov: The Split Ph Domain of Rock II
- 2bfx: Mechanism of Aurora-b Activation by Incenp and Inhibition by Hesperidin.
- 2bfy: Complex of Aurora-b with Incenp and Hesperidin.
- 2rjm: 3ig Structure of Titin Domains I67-i69 E-to-a Mutated Variant
- 2rio: Structure of The Dual Enzyme Ire1 Reveals The Basis for Catalysis and Regulation of Non-conventional Splicing
- 2rik: I-band Fragment I67-i69 from Titin
- 2r7i: Crystal Structure of Catalytic Subunit of Protein Kinase Ck2
- 2r7b: Crystal Structure of The Phosphoinositide-dependent Kinase- 1 (pdk-1)catalytic Domain Bound to a Dibenzonaphthyridine Inhibitor
- 2r5t: Crystal Structure of Inactive Serum and Glucocorticoid- Regulated Kinase 1 in Complex with Amp-pnp
- 2r0u: Crystal Structure of Chek1 in Complex with Inhibitor 54
- 2r0i: Crystal Structure of a Kinase Mark2/par-1 Mutant
- 2qre: Crystal Structure of The Adenylate Sensor from Amp- Activated Protein Kinase in Complex with 5-aminoimidazole- 4-carboxamide 1-beta-d-ribofuranotide (zmp)
- 2qrd: Crystal Structure of The Adenylate Sensor from Amp- Activated Protein Kinase in Complex with Adp and Atp
- 2qrc: Crystal Structure of The Adenylate Sensor from Amp- Activated Protein Kinase in Complex with Adp and Amp
- 2qr8: 2.0a X-ray Structure of C-terminal Kinase Domain of P90 Ribosomal S6 Kinase 2 (rsk2)
- 2qr7: 2.0a X-ray Structure of C-terminal Kinase Domain of P90 Ribosomal S6 Kinase 2: Se-met Derivative
- 2qr1: Crystal Structure of The Adenylate Sensor from Amp- Activated Protein Kinase in Complex with Adp
- 2qnj: Kinase and Ubiquitin-associated Domains of Mark3/par-1
- 2qme: Crystal Structure of Human Rac3 in Complex with Crib Domain of Human P21-activated Kinase 1 (pak1)
- 2qlv: Crystal Structure of The Heterotrimer Core of The S. Cerevisiae Ampk Homolog Snf1
- 2qkw: Structural Basis for Activation of Plant Immunity by Bacterial Effector Protein Avrpto
- 2qhn: Crystal Structure of Chek1 in Complex with Inhibitor 1a
- 2qhm: Crystal Structure of Chek1 in Complex with Inhibitor 2a
- 2cke: Human Death-associated Drp-1 Kinase in Complex with Inhibitor
- 2qc6: Protein Kinase Ck2 in Complex with Dbc
- 2cmw: Structure of Human Casein Kinase 1 Gamma-1 in Complex with 2-(2-hydroxyethylamino)-6-(3-chloroanilino)-9- Isopropylpurine (casp Target)
- 2cn5: Crystal Structure of Human Chk2 in Complex with Adp
- 2cn8: Crystal Structure of Human Chk2 in Complex with Debromohymenialdisine
- 2q0n: Structure of Human P21 Activating Kinase 4 (pak4) in Complex with a Consensus Peptide
- 2pzy: Structure of Mk2 Complexed with Compound 76
- 2pzi: Crystal Structure of Protein Kinase Pkng from Mycobacterium Tuberculosis in Complex with Tetrahydrobenzothiophene Ax20017
- 2pvr: Crystal Structure of The Catalytic Subunit of Protein Kinase Ck2 (c-terminal Deletion Mutant 1-335) in Complex with Two Sulfate Ions
- 2pvn: Structure-based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase Ck2
- 2pvm: Structure-based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase Ck2
- 2pvl: Structure-based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase Ck2
- 2pvk: Structure-based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase Ck2
- 2pvj: Structure-based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase Ck2
- 2pvh: Structure-based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase Ck2
- 2pe2: Crystal Structure of Human Phosphoinositide-dependent Protein Kinase 1 (pdk1) 3-{5-[2-oxo-5-ureido-1,2-dihydro- Indol-(3z)-ylidenemethyl]-1h-pyrrol-3-yl}-n-(2-piperidin-1- Yl-ethyl)-benzamide Complex
- 2pe1: Crystal Structure of Human Phosphoinositide-dependent Protein Kinase 1 (pdk1) {2-oxo-3-[1-(1h-pyrrol-2-yl)-eth- (z)-ylidene]-2,3-dihydro-1h-indol-5-yl}-urea {bx-517} Complex
- 2pe0: Crystal Structure of Human Phosphoinositide-dependent Protein Kinase 1 (pdk1) 5-hydroxy-3-[1-(1h-pyrrol-2-yl)- Eth-(z)-ylidene]-1,3-dihydro-indol-2-one Complex
- 2p3g: Crystal Structure of a Pyrrolopyridine Inhibitor Bound to Mapkap Kinase-2
- 2oza: Structure of P38ALPHA Complex
- 2oxy: Protein Kinase Ck2 in Complex with Tetrabromobenzoimidazole Derivatives K17, K22 and K32
- 2oxx: Protein Kinase Ck2 in Complex with Tetrabromobenzoimidazole Derivatives K17, K22 and K32
- 2oxd: Protein Kinase Ck2 in Complex with Tetrabromobenzoimidazole K17, K22 and K32 Inhibitors
- 2ov2: The Crystal Structure of The Human Rac3 in Complex with The Crib Domain of Human P21-activated Kinase 4 (pak4)
- 6z3a: Mec1-ddc2 (wild-type) in Complex with Amp-pnp
- 6z2x: Mec1-ddc2 (F2244L Mutant) in Complex with Mg Amp-pnp (state Ii)
- 6z2w: Mec1-ddc2 (F2244L Mutant) in Complex with Mg Amp-pnp
- 2ooy: Crystal Structure of The Adenylate Sensor from Amp- Activated Protein Kinase Complexed with Atp
- 2oox: Crystal Structure of The Adenylate Sensor from Amp- Activated Protein Kinase Complexed with Amp
- 2onl: Crystal Structure of The P38A-MAPKAP Kinase 2 Heterodimer
- 2okr: Crystal Structure of The P38A-MAPKAP Kinase 2 Heterodimer
- 6ypn: Crystal Structure of CK2ALPHA with 2 Molecules of Adp Bound
- 6ypk: Crystal Structure of CK2ALPHA with Gtp Bound
- 6ypj: Crystal Structure of CK2ALPHA with Compound 1 Bound
- 6yph: Crystal Structure of CK2ALPHA with Compound 2 Bound
- 6ypg: Crystal Structure of CK2ALPHA with Compound 2 Bound to Second Crystal Form
- 6ykd: Human Pim-1 Kinase in Complex with an Inhibitor Identified by Virtual Screening
- 2oid: Crystal Structure of Irak4 Kinase Domain Complexed with Amppnp
- 2oic: Crystal Structure of Irak4 Kinase Domain Complexed with Staurosporine
- 2oib: Crystal Structure of Irak4 Kinase Domain Apo Form
- 2oi4: Crystal Structure of Human Pim1 in Complex with Fluorinated Ruthenium Pyridocarbazole
- 6y9o: Crystal Structure of Whirlin Pdz3_c-ter in Complex with Cask Internal Pdz Binding Motif Peptide
- 6xwe: Crystal Structure of Lyk3 Ectodomain
- 2obj: Crystal Structure of Human Pim-1 Kinase in Complex with Inhibitor
- 6xrm: Crystal Structure of Human PI3K-GAMMA in Complex with Compound 4
- 6xrl: Crystal Structure of Human PI3K-GAMMA in Complex with Inhibitor Ipi- 549
- 6xr4: Integrative in Situ Structure of Parkinsons Disease-linked Human Lrrk2
- 2o8y: Apo Irak4 Kinase Domain
- 6xka: Tpx2 Residues 7-20 Fused to Aurora a Residues 116-389 Dephosphorylated, and Coalated on C290
- 6c83: Structure of Aurora a (122-403) Bound to Inhibitory Monobody Mb2 and Amppcp
- 6c4d: Structure Based Design of Rip1 Kinase Inhibitors
- 6c3e: Crystal Structure of Rip1 Kinase Bound to Inhibitor
- 6c2t: Aurora a Ligand Complex
- 6c2r: Aurora a Ligand Complex
- 6c1s: Phosphoinositide 3-kinase Gamma Bound to an Pyrrolopyridinone Inhibitor
- 6bxi: X-ray Crystal Structure of Ndr1 Kinase Domain
- 6bx6: Amp-activated Protein Kinase (ampk) Inhibition by Sbi-0206965: Alpha 2 Kinase Domain Bound to Sbi-0206965
- 6buu: Crystal Structure of Akt1 (aa 144-480) with a Bisubstrate
- 6bu6: Crystal Structure of The Human Vaccinia-related Kinase Bound to a Bis- Difluorophenol-aminopyridine Inhibitor
- 6btw: Crystal Structure of The Human Vaccinia-related Kinase Bound to a Phenyl-pteridinone Inhibitor
- 6bsk: Human Pim1 Kinase in Complex with Compound 12b
- 6bru: Crystal Structure of The Human Vaccinia-related Kinase Bound to a (s)- 2-phenylaminopteridinone Inhibitor
- 6bqd: Taf1-bd2 Bromodomain in Complex with (e)-3-(6-(but-2-en-1-yl)-7-oxo-6, 7-dihydro-1h-pyrrolo[2,3-c]pyridin-4-yl)-n,n-dimethylbenzamide
- 6bp0: Crystal Structure of The Human Vaccinia-related Kinase 1 Bound to (r)- 2-phenylaminopteridinone Inhibitor
- 6boe: Tbk1 in Complex with Amide-coupled Tetrazole Analog of Amlexanox
- 6bod: Tbk1 in Complex with Ethyl Ester Analog of Amlexanox
- 6bny: Tbk1 in Complex with Tetrazole Analog of Amlexanox
- 6bn1: Salvador Hippo Sarah Domain Complex
- 6bfn: Crystal Structure of Human Irak1
- 2dwb: Aurora-a Kinase Complexed with Amppnp
- 2o65: Crystal Structure of Pim1 with Pentahydroxyflavone
- 2o64: Crystal Structure of Pim1 with Quercetagetin
- 2o63: Crystal Structure of Pim1 with Myricetin
- 6bdn: Crystal Structure of Human Tao3 Kinase Binding Adp
- 2o3p: Crystal Structure of Pim1 with Quercetin
- 6b8u: Crystals Structure of B-raf Kinase Domain in Complex with an Imidazopyridinyl Benzamide Inhibitor
- 6b8j: Co-structure of Human Glycogen Synthase Kinase Beta with a Selective (5-imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino) Ethyl]amine Inhibitor
- 6b5j: TNNI3K Complexed with a 4,6-diaminopyrimidine
- 2nzi: Crystal Structure of Domains A168-a170 from Titin
- 6b2q: Dual Inhibition of The Essential Protein Kinases a and B in Mycobacterium Tuberculosis
- 6b2p: Dual Inhibition of The Essential Protein Kinases a and B in Mycobacterium Tuberculosis
- 6b2e: Structure of Full Length Human Ampk (A2B2G1) in Complex with a Small Molecule Activator Sc4.
- 6b1u: Structure of Full-length Human Ampk (A2B1G1) in Complex with a Small Molecule Activator Sc4
- 6b16: P21-activated Kinase 1 in Complex with a 4-azaindole Inhibitor
- 6ayd: Pim1 Complexed with N-(6-(4-hydroxyphenyl)-1h-indazol-3-yl) Cyclopropanecarboxamide
- 6aud: PI3K-GAMMA K802T in Complex with Cpd 8 10-((1-(tert-butyl)piperidin-4- Yl)sulfinyl)-2-(1-isopropyl-1h-1,2,4-triazol-5-yl)-5,6- Dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine
- 2nry: Crystal Structure of Irak-4
- 2nru: Crystal Structure of Irak-4
- 2e9n: Structure of H-chk1 Complexed with A767085
- 2e9o: Structure of H-chk1 Complexed with Aa582939
- 2e9p: Structure of H-chk1 Complexed with A771129
- 2e9u: Structure of H-chk1 Complexed with A780125
- 2e9v: Structure of H-chk1 Complexed with A859017
- 6ao5: Crystal Structure of Human Mst2 in Complex with Sav1 Sarah Domain
- 2np8: Structural Basis for The Inhibition of Aurora a Kinase by a Novel Class of High Affinity Disubstituted Pyrimidine Inhibitors
- 6ae3: Crystal Structure of GSK3BETA Complexed with Morin
- 6ac9: Crystal Structure of Human Vaccinia-related Kinase 1 (vrk1) in Complex with Amp-pnp
- 6ac5: Crystal Structure of Ripk1 Death Domain Glcnacylated by Epec Effector Nleb
- 6aar: Crystal Structure of Dapk1 in Complex with Purpurin
- 6a5e: Crystal Structure of Plant Peptide Ralf23 in Complex with fer and Llg2
- 6a5c: Crystal Structure of Plant Receptor-like Kinase Anx2
- 6a5b: Crystal Structure of Plant Receptor-like Kinase fer
- 6a5a: Crystal Structure of Plant Receptor-like Kinase Anx1
- 6a1c: Crystal Structure of The CK2A1-GO289 Complex
- 5zxb: Crystal Structure of Ack1 with Compound 10d
- 5zx5: 3.3 Angstrom Structure of Mouse Trpm7 with Edta
- 2ehb: The Structure of The C-terminal Domain of The Protein Kinase Atsos2 Bound to The Calcium Sensor Atsos3
- 2l05: Solution Nmr Structure of The Ras-binding Domain of Serine/threonine- Protein Kinase B-raf from Homo Sapiens, Northeast Structural Genomics Consortium Target HR4694F
- 5zn5: X-ray Structure of Protein Kinase Ck2 Alpha Subunit H148A Mutant
- 5zn4: X-ray Structure of Protein Kinase Ck2 Alpha Subunit H148N Mutant
- 5zn3: X-ray Structure of Protein Kinase Ck2 Alpha Subunit H148S Mutant
- 5zn2: X-ray Structure of Protein Kinase Ck2 Alpha Subunit H148A Mutant
- 5zn1: X-ray Structure of Protein Kinase Ck2 Alpha Subunit in D2O
- 5zn0: Joint X-ray/neutron Structure of Protein Kinase Ck2 Alpha Subunit
- 5zjw: Crystal Structure of Pak4 in Complex with Inhibitor Czg353
- 5zcs: 4.9 Angstrom Cryo-em Structure of Human Mtor Complex 2
- 2kui: Nmr Structure of The Pasta Domain of Mycobacterium Tuberculosis of Pknb
- 2kuf: Nmr Structure of The Pasta Domain 3 and 4 of Mycobacterium Tuberculosis of Pknb
- 2kue: Nmr Structure of The Pasta Domain 2 and 3 of Mycobacterium Tuberculosis of Pknb
- 2kud: Nmr Structure of The Pasta Domain 1 and 2 of Mycobacterium Tuberculosis of Pknb
- 5zan: Crystal Structure of Aurora-a in Complex with a New Quinazoline Inhibitor
- 5yzv: Biophysical and Structural Characterization of The Thermostable Wd40 Domain of a Prokaryotic Protein, Thermomonospora Curvata Pkwa
- 5yz8: Crystal Structure of N-terminal C1 Domain of Kaic
- 5yz0: Cryo-em Structure of Human Atr-atrip Complex
- 5yyz: Crystal Structure of The Mek1 Fha Domain in Complex with The Hop1 Pthr318 Peptide.
- 5yyx: Crystal Structure of The Mek1 Fha Domain
- 6l24: Crystal Structure of CK2A1 H115Y/V116I with Hematein
- 5ywm: Crystal Structure of CK2A2 Form-1
- 2h34: Apoenzyme Crystal Structure of The Tuberculosis Serine/threonine Kinase, Pkne
- 5yrn: Structure of Rip2 Card Domain
- 2h6d: Protein Kinase Domain of The Human 5'-amp-activated Protein Kinase Catalytic Subunit Alpha-2 (ampk Alpha-2 Chain)
- 2h9v: Structural Basis for Induced-fit Binding of Rho-kinase to The Inhibitor Y27632
- 2hak: Catalytic and Ubiqutin-associated Domains of Mark1/par-1
- 6g78: Rsk4 N-terminal Kinase Domain S232E in Complex with Amp-pnp
- 6g77: Rsk4 N-terminal Kinase Domain in Complex with Amp-pnp
- 6g76: Phosphorylated Rsk4 N-terminal Kinase Domain in Complex with Amp-pnp
- 6pxo: Human Casein Kinase 1 Delta (anion-free Crystallization Conditions)
- 6pxp: Human Casein Kinase 1 Delta Site 2 Mutant (K171E)
- 6u5l: Structure of Human Ulk4 in Complex with an Inhibitor
- 6tsz: The Ulk4 Pseudokinase Domain Bound to Atpgammas
- 6t3c: Crystal Structure of PI3KGAMMA in Complex with Dna-pk Inhibitor Azd7648
- 6t3b: Crystal Structure of PI3KGAMMA with a Dihydropurinone Inhibitor (compound 4)
- 6syt: Structure of The Smg1-smg8-smg9 Complex
- 2hog: Crystal Structure of Chek1 in Complex with Inhibitor 20
- 2hw6: Crystal Structure of Mnk1 Catalytic Domain
- 2hw7: Crystal Structure of MNK2-D228G in Complex with Staurosporine
- 2hxl: Crystal Structure of Chek1 in Complex with Inhibitor 1
- 2hxq: Crystal Structure of Chek1 in Complex with Inhibitor 2
- 2hy0: Crystal Structure of Chek1 in Complex with Inhibitor 22
- 2hy8: Pak1 Complex with St2001
- 2i3s: Bub3 Complex with Bub1 Glebs Motif
- 2ill: Anomalous Substructure of Titin-a168169
- 2iwi: Crystal Structure of The Human Pim2 in Complex with a Ruthenium Organometallic Ligand Ru1
- 2izr: Structure of Casein Kinase Gamma 3 in Complex with Inhibitor
- 2izs: Structure of Casein Kinase Gamma 3 in Complex with Inhibitor
- 2izt: Structure of Casein Kinase Gamma 3 in Complex with Inhibitor
- 2izu: Structure of Casein Kinase Gamma 3 in Complex with Inhibitor
- 2j0i: Crystal Structure of The Human P21-activated Kinase 4
- 2j2i: Crystal Structure of The Humab Pim1 in Complex with Ly333531
- 2j4z: Structure of Aurora-2 in Complex with Pha-680626
- 2j50: Structure of Aurora-2 in Complex with Pha-739358
- 2j51: Crystal Structure of Human Ste20-like Kinase Bound to 5- Amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6- Difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
- 2j7t: Crystal Structure of Human Serine Threonine Kinase-10 Bound to Su11274
- 2j8h: Structure of The Immunoglobulin Tandem Repeat A168-a169 of Titin
- 2j8o: Structure of The Immunoglobulin Tandem Repeat of Titin A168- A169
- 2j90: Crystal Structure of Human Zip Kinase in Complex with a Tetracyclic Pyridone Inhibitor (pyridone 6)
- 2jbo: Protein Kinase Mk2 in Complex with an Inhibitor (crystal Form-1, Soaking)
- 2jbp: Protein Kinase Mk2 in Complex with an Inhibitor (crystal Form-2, Co-crystallization)
- 2jd5: SKY1P Bound to NPL3P-DERIVED Substrate Peptide
- 2jdo: Structure of Pkb-beta (akt2) Complexed with Isoquinoline-5- Sulfonic Acid (2-(2-(4-chlorobenzyloxy) Ethylamino)ethyl) Amide
- 2jdr: Structure of Pkb-beta (akt2) Complexed with The Inhibitor A- 443654
- 2jfl: Crystal Structure of Human Ste20-like Kinase ( Diphosphorylated Form) Bound to 5- Amino-3-((4-( Aminosulfonyl)phenyl)amino)-n-(2,6- Difluorophenyl)-1h-1,2, 4-triazole-1-carbothioamide
- 2jfm: Crystal Structure of Human Ste20-like Kinase (unliganded Form)
- 2jii: Structure of Vaccinia Related Kinase 3
- 6xag: Apo Braf Dimer Bound to 14-3-3
- 2jo8: Solution Structure of C-terminal Domain of Human Mammalian Sterile 20-like Kinase 1 (mst1)
- 2jqi: Nmr Structure of The Rad53 Fha1 Domain in Complex with a Phosphothreonien Peptide Derived from Rad53 Scd1
- 2jqj: Nmr Structure of Yeast Dun1 Fha Domain
- 2jql: Nmr Structure of The Yeast Dun1 Fha Domain in Complex with a Doubly Phosphorylated (pt) Peptide Derived from Rad53 Scd1
- 6w3k: Structure of Unphosphorylated Human Ire1 Bound to G-9807
- 6w3e: Structure of Phosphorylated Ire1 in Complex with G-0701
- 6w3c: Structure of Phosphorylated Apo Ire1
- 6w3b: Structure of Apo Unphosphorylated Ire1
- 6w3a: Structure of Unphosphorylated Ire1 in Complex with G-7658
- 6w39: Structure of Unphosphorylated Ire1 in Complex with G-1749
- 6vxr: Structure of Maternal Embryonic Leucine Zipper Kinase Bound to Ldsm276
- 6vrv: Discovery of Sarxxxx92, a Pan-pim Kinase Inhibitor, Efficacious in a Kg1 Tumor Model
- 6vru: Pim-inhibitor Complex 1
- 6vpm: Tpx2 Residues 7-20 Fused to Aurora a Residues 116-389 with C290 Disulfide Bonded to Compound 8-34, and in Complex with Amp-pnp
- 6vpl: Tpx2 Residues 7-20 Fused to Aurora a Residues 116-389 with C290 Disulfide Bonded to Compound 7-80, and in Complex with Amp-pnp
- 6vpj: Tpx2 Residues 7-20 Fused to Aurora a Residues 116-389 C247V + C319V Double Mutant Dephosphorylated, and in Complex with Amp-pnp
- 6vpi: Tpx2 Residues 7-20 Fused to Aurora a Residues 116-389 C247V + D256N + C319V Triple Mutant Disulfide Homodimer in Complex with Amp-pnp
- 6vph: Tpx2 Residues 7-20 Fused to Aurora a Residues 116-389 Modified with Cacodylate and in Complex with Amp-pnp
- 6vpg: Tpx2 Residues 7-20 Fused to Aurora a Residues 116-389 in Complex with Amp-pnp
- 6vp8: Cryo-em Structure of The C-terminal Half of The Parkinson's Disease- Linked Protein Leucine Rich Repeat Kinase 2 (lrrk2)
- 6vp7: Cryo-em Structure of The C-terminal Half of The Parkinson's Disease- Linked Protein Leucine Rich Repeat Kinase 2 (lrrk2)
- 6vp6: Cryo-em Structure of The C-terminal Half of The Parkinson's Disease- Linked Protein Leucine Rich Repeat Kinase 2 (lrrk2)
- 6vno: Cryo-em Structure of The C-terminal Half of The Parkinson's Disease- Linked Protein Leucine Rich Repeat Kinase 2 (lrrk2)
- 6vjj: Crystal Structure of Wild-type KRAS4B (gmppnp-bound) in Complex with Ras-binding Domain (rbd) of Raf1/craf
- 6v2w: Crystal Structure of The Braf:mek1 Kinases in Complex with Amppnp
- 6v2u: Crystal Structure of The Insect Cell-expressed Wt-braf Kinase in Complex with Dabrafenib
- 6tia: Irak4 in Complex with Inhibitor
- 6ti8: Irak4 in Complex with Inhibitor
- 6thz: Irak4 in Complex with Inhibitor
- 6thx: Irak4 in Complex with Inhibitor
- 6thw: Irak4 in Complex with Inhibitor
- 6tgu: Crystal Structure of Human Protein Kinase CK2ALPHA'(CSNK2A2 Gene Product) in Complex with The 2-aminothiazole-type Inhibitor Cl-oh-3
- 2kbx: Solution Structure of Ilk-pinch Complex
- 6tew: Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with The 2-aminothiazole-type Inhibitor 27
- 6tei: Crystal Structure of Human Protein Kinase CK2ALPHA (CSNK2A1 Gene Product) in Complex with The 2-aminothiazole-type Inhibitor 17
- 6te2: Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with The 2-aminothiazole-type Inhibitor 17
- 6tcu: Glycogen Synthase Kinase-3 Beta (GSK3B) in Complex with Ligand 1
- 6tca: Phosphorylated P38 and Mapkapk2 Complex with Inhibitor
- 6seq: Lemur Tyrosine Kinase 3 (lmtk3)
- 6s46: Room Temperature Structure of The Lov2 Domain of Phototropin-2 from Arabidopsis Thaliana 4158 Ms after Initiation of Illumination, Determined with a Serial Crystallography Approach
- 6s45: Room Temperature Structure of The Dark State of The Lov2 Domain of Phototropin-2 from Arabidopsis Thaliana Determined with a Serial Crystallography Approach
- 2kio: Nmr Structure of The Oxidized Yeast Tor1 Fatc Domain Bound to Dpc Micelles at 318k
- 2kit: The Solution Struture of The Reduced Yeast Tor1 Fatc Domain Bound to Dpc Micelles at 298k
- 6ruu: Pseudokinase Domain of Human Irak3
- 6p7g: The Co-crystal Structure of BRAF(V600E) with Phi1
- 6p3d: The Co-crystal Structure of BRAF(V600E) with Ponatinib
- 6ojf: Dimeric Structure of Lrrk2 Gtpase Domain
- 6oje: Dimeric Structure of Lrrk2 Gtpase Domain
- 6m4w: Crystal Structure of Mbp Fused Split Fkbp-frb T2098L Mutant in Complex with Rapamycin
- 6m4u: Crystal Structure of Fkbp-frb T2098L Mutant in Complex with Rapamycin
- 6m37: The Crystal Structure of B. Subtilis Rsbv/rsbw Complex in The Hexagonal Crystal Form
- 6m36: The Crystal Structure of B. Subtilis Rsbv/rsbw Complex in The Monoclinic Crystal Form
- 6lxy: Irak4 in Complex with Inhibitor
- 6l17: Crystal Structure of Ser/thr Kinase Pim1 in Complex with 10-debc Derivatives
- 6kyr: Crystal Structure of Dclk1 Mutant (P675L) Autoinhibited Kinase Domain
- 6kyq: Crystal Structure of Dclk1 Autoinhibited Kinase Domain
- 6kmh: The Crystal Structure of Cask/mint1 Complex
- 3ncz: X-ray Co-structure of Rho-associated Protein Kinase (rock1) with a Potent 2h-isoquinolin-1-one Inhibitor
- 6jpd: Mouse Receptor-interacting Protein Kinase 3 (rip3) Amyloid Structure by Solid-state Nmr
- 3pa3: X-ray Crystal Structure of Compound 70 Bound to Human Chk1 Kinase Domain
- 3pa4: X-ray Crystal Structure of Compound 2a Bound to Human Chk1 Kinase Domain
- 3pa5: X-ray Crystal Structure of Compound 1 Bound to Human Chk1 Kinase Domain
- 3pm8: Cad Domain of PFF0520W, Calcium Dependent Protein Kinase
- 2kr9: Kalirin Dh1 Nmr Structure
- 2kty: Solution Structure of Human Vaccinia Related Kinase-1
- 2kul: Solution Structure of Human Vaccinia Related Kinase 1(vrk1)
- 6z3r: Structure of Smg1-8-9 Kinase Complex Bound to Upf1-lsq
- 6wly: Pak4 Kinase Domain in Complex with Limk1 Thr508 Substrate Peptide
- 6wlx: Pak4 Kinase Domain in Complex with Beta-catenin Ser675 Substrate Peptide
- 6vql: Crystal Structure of Interleukin-1 Receptor-associated Kinase 4 (irak4-wt) Complex with a Nicotinamide Inhibitor
- 2xbj: Crystal Structure of Chk2 in Complex with an Inhibitor
- 2xix: Protein Kinase Pim-1 in Complex with Fragment-1 from Crystallographic Fragment Screen
- 2xiy: Protein Kinase Pim-1 in Complex with Fragment-2 from Crystallographic Fragment Screen
- 2xiz: Protein Kinase Pim-1 in Complex with Fragment-3 from Crystallographic Fragment Screen
- 2xj0: Protein Kinase Pim-1 in Complex with Fragment-4 from Crystallographic Fragment Screen
- 2xj1: Protein Kinase Pim-1 in Complex with Small Molecule Inibitor
- 2xj2: Protein Kinase Pim-1 in Complex with Small Molecule Inhibitor
- 2xm8: Co-crystal Structure of a Small Molecule Inhibitor Bound to The Kinase Domain of Chk2
- 2xm9: Structure of a Small Molecule Inhibitor with The Kinase Domain of Chk2
- 6yid: Crystal Structure of Ulk2 in Complex with Sbi-0206965
- 2y9r: Crystal Structure of The M10 Domain of Titin
- 6sk9: Nek2 Bound to Purine Compound 51
- 6sgk: Nek2 Kinase Bound to Inhibitor 102
- 6sgi: Nek2 Kinase Bound to Inhibitor 96
- 6sgh: Nek2 Kinase Covalently Bound to 2-arylamino-6-ethynylpurine Inhibitor 66
- 6sgd: Nek2 Kinase Covalently Bound to 2-arylamino-6-ethynylpurine Inhibitor 24
- 6s76: Crystal Structure of Human Nek7
- 3nga: Human Ck2 Catalytic Domain in Complex with Cx-4945
- 6s75: Crystal Structure of Nek7 Bound to Compound 51
- 6s73: Crystal Structure of Nek7 Srs Mutant Bound to Compound 51
- 3nsz: Human Ck2 Catalytic Domain in Complex with Amppn
- 6z5e: Crystal Structure of Haspin (gsg2) in Complex with Macrocycle Ods2004093
- 6z5d: Crystal Structure of Haspin (gsg2) in Complex with Macrocycle Ods2004082
- 6z5c: Crystal Structure of Haspin (gsg2) in Complex with Macrocycle Ods2004070
- 6z5b: Crystal Structure of Haspin (gsg2) in Complex with Macrocycle Ods2003128
- 6z5a: Crystal Structure of Haspin (gsg2) in Complex with Macrocycle Ods2002941
- 6z59: Crystal Structure of Haspin (gsg2) in Complex with Macrocycle Ods2003816
- 6z58: Crystal Structure of Haspin (gsg2) in Complex with Macrocycle Ods2003791
- 6z57: Crystal Structure of Haspin (gsg2) in Complex with Macrocycle Ods2004078
- 6z56: Crystal Structure of Haspin (gsg2) in Complex with Macrocycle Ods2003208
- 6z4y: Crystal Structure of Aurora a (stk6) in Complex with Macrocycle Ods2003208
- 3ofm: Structure of a Human CK2ALPHA Prime, The Paralog Isoform of The Catalytic Subunit of Protein Kinase Ck2 from Homo Sapiens
- 3ose: Structure of The Kinase Associated Domain 1 (ka1) from Mark1 Kinase
- 3osm: Structure of The Kinase Associated Domain-1 (ka1) from KCC4P
- 3ost: Structure of The Kinase Associated-1 (ka1) from KCC4P
- 6vrf: Adp Bound Ttbk2 Kinase Domain
- 6uuo: Crystal Structure of Braf Kinase Domain Bound to The Protac P4B
- 3p23: Crystal Structure of The Human Kinase and Rnase Domains in Complex with Adp
- 3pcs: Structure of Espg-pak2 Autoinhibitory Ialpha3 Helix Complex
- 3ppj: Human B-raf Kinase in Complex with a Furopyridine Inhibitor
- 3ppk: Human B-raf Kinase in Complex with a Non-oxime Furopyridine Inhibitor
- 3prf: Crystal Structure of Human B-raf Kinase Domain in Complex with a Non- Oxime Furopyridine Inhibitor
- 3pri: Crystal Structure of Human B-raf Kinase in Complex with a Non-oxime Furopyridine Inhibitor
- 3ps4: Pdz Domain from Human Microtubule-associated Serine/threonine-protein Kinase 1
- 3psb: Furo[2,3-c]pyridine-based Indanone Oximes as Potent and Selective B- Raf Inhibitors
- 6ya8: Cdc7-dbf4 Bound to Adp-bef3
- 6ya7: Cdc7-dbf4 Bound to an Mcm2-s40 Derived Bivalent Substrate
- 6ya6: Minimal Construct of Cdc7-dbf4 Bound to Xl413
- 3pvg: Crystal Structure of Z. Mays Ck2 Alpha Subunit in Complex with The Inhibitor 4,5,6,7-tetrabromo-1-carboxymethylbenzimidazole (k68)
- 3q4c: Crystal Structure of Wild Type Braf Kinase Domain in Complex with Organometallic Inhibitor Cns292
- 3q5z: Crystal Structure of Virulent Allele ROP5B Pseudokinase Domain
- 3q60: Crystal Structure of Virulent Allele ROP5B Pseudokinase Domain Bound to Atp
- 6p3a: Crystal Structure Analysis of Taf1 Bromodomain
- 6p39: Crystal Structure Analysis of Taf1 Bromodomain
- 6p38: Crystal Structure Analysis of Taf1 Bromodomain
- 6l16: Crystal Structure of Ser/thr Kinase Pim1 in Complex with 10-debc Derivatives
- 6l15: Crystal Structure of Ser/thr Kinase Pim1 in Complex with 10-debc Derivatives
- 6l14: Crystal Structure of Ser/thr Kinase Pim1 in Complex with 10-debc Derivatives
- 6l13: Crystal Structure of Ser/thr Kinase Pim1 in Complex with 10-debc Derivatives
- 6l12: Crystal Structure of Ser/thr Kinase Pim1 in Complex with 10-debc Derivatives
- 6l11: Crystal Structure of Ser/thr Kinase Pim1 in Complex with 10-debc Derivatives
- 3qf9: Crystal Structure of Human Proto-oncogene Serine Threonine Kinase (pim1) in Complex with a Consensus Peptide and a Furan- Thiazolidinedione Ligand
- 6y9s: Crystal Structure of Gsk-3b in Complex with The Imidazo[1,5- A]pyridine-3-carboxamide Inhibitor 16
- 6y9r: Crystal Structure of Gsk-3b in Complex with The 1h-indazole-3- Carboxamide Inhibitor 2
- 2xnm: Structure of Nek2 Bound to Cct
- 2xnn: Structure of Nek2 Bound to Cct242430
- 2xno: Structure of Nek2 Bound to Cct243779
- 2xnp: Structure of Nek2 Bound to Cct244858
- 6jlr: Crystal Structure of Wild Type Mnk2 in Complex with Inhibitor
- 2y8l: Structure of The Regulatory Fragment of Mammalian Ampk in Complex with Two Adp
- 2y8q: Structure of The Regulatory Fragment of Mammalian Ampk in Complex with One Adp
- 2ya3: Structure of The Regulatory Fragment of Mammalian Ampk in Complex with Coumarin Adp
- 2ya9: Crystal Structure of The Autoinhibited Form of Mouse Dapk2
- 2yaa: Crystal Structure of The Autoinhibited Form of Mouse Dapk2 in Complex with Atp
- 2yab: Crystal Structure of The Autoinhibited Form of Mouse Dapk2 in Complex with Amp
- 2yak: Structure of Death-associated Protein Kinase 1 (dapk1) in Complex with a Ruthenium Octasporine Ligand (osv)
- 3aqv: Human Amp-activated Protein Kinase Alpha 2 Subunit Kinase Domain (T172D) Complexed with Compound C
- 3m11: Crystal Structure of Aurora a Kinase Complexed with Inhibitor
- 3m42: Crystal Structure of Mapkap Kinase 2 (mk2) Complexed with a Tetracyclic Atp Site Inhibitor
- 3o0z: Crystal Structure of a Coiled-coil Domain from Human Rock I
- 6ru8: Crystal Structure of Casein Kinase I Delta (CK1D) in Complex with Triple Phosphorylated P63 PAD3P Peptide
- 6ru7: Crystal Structure of Casein Kinase I Delta (CK1D) in Complex with Double Phosphorylated P63 PAD2P Peptide
- 6ru6: Crystal Structure of Casein Kinase I Delta (CK1D) in Complex with Monophosphorylated P63 PAD1P Peptide
- 3orx: Pdk1 Mutant Bound to Allosteric Disulfide Fragment Inhibitor 1f8
- 3orz: Pdk1 Mutant Bound to Allosteric Disulfide Fragment Activator 2a2
- 3otu: Pdk1 Mutant Bound to Allosteric Disulfide Fragment Activator Js30
- 3p9j: Aurora a Kinase Domain with Phthalazinone Pyrazole Inhibitor
- 3pwy: Crystal Structure of an Extender (spd28345)-modified Human Pdk1 Complex 2
- 3q96: B-raf Kinase Domain in Complex with a Tetrahydronaphthalene Inhibitor
- 3qc4: Pdk1 in Complex with Dfg-out Inhibitor XXX
- 3qcq: Phosphoinositide-dependent Kinase-1 (pdk1) Kinase Domain with 6-(3- Amino-1h-indazol-6-yl)-n4-ethyl-2,4-pyrimidinediamine
- 3qcs: Phosphoinositide-dependent Kinase-1 (pdk1) Kinase Domain with 6-[2- Amino-6-(4-morpholinyl)-4-pyrimidinyl]-1h-indazol-3-amine
- 3qcx: Phosphoinositide-dependent Kinase-1 (pdk1) Kinase Domain with 6-{2- Amino-6-[(3r)-3-methyl-4-morpholinyl]-4-pyrimidinyl}-1h-indazol-3- Amine
- 3qcy: Phosphoinositide-dependent Kinase-1 (pdk1) Kinase Domain with 4-[2- Amino-6-(3-amino-1h-indazol-6-yl)-4-pyrimidinyl]-n-phenyl-2- Morpholinecarboxamide
- 3qd0: Phosphoinositide-dependent Kinase-1 (pdk1) Kinase Domain with (2r,5s)- 1-[2-amino-6-(3-amino-1h-indazol-6-yl)-4-pyrimidinyl]-6-methyl-n- Phenyl-3-piperidinecarboxamide
- 3qd2: Crsytal Structure of Mouse Perk Kinase Domain
- 3qd3: Phosphoinositide-dependent Kinase-1 (pdk1) Kinase Domain with 1,1- Dimethylethyl {(3r,6s)-1-[2-amino-6-(3-amino-1h-indazol-6-yl)-4- Pyrimidinyl]-6-methyl-3-piperidinyl}carbamate
- 3qd4: Phosphoinositide-dependent Kinase-1 (pdk1) Kinase Domain with 1,1- Dimethylethyl{(3r,5r)-1-[2-amino-6-(3-amino-1h-indazol-6-yl)-4- Pyrimidinyl]-5-methyl-3-piperidinyl}carbamate
- 3qkk: Spirochromane Akt Inhibitors
- 3qkl: Spirochromane Akt Inhibitors
- 3qkm: Spirocyclic Sulfonamides as Akt Inhibitors
- 6ra5: Human Tnik in Complex with Compound 9
- 6yat: Crystal Structure of Stk4 (mst1) in Complex with Compound 6
- 2lav: Nmr Solution Structure of Human Vaccinia-related Kinase 1
- 2lah: Solution Nmr Structure of Mitotic Checkpoint Serine/threonine-protein Kinase Bub1 N-terminal Domain from Homo Sapiens, Northeast Structural Genomics Consortium Target HR5460A (methods Development)
- 3r00: The Discovery of Novel Benzofuran-2-carboxylic Acids as Potent Pim-1 Inhibitors
- 3r01: The Discovery of Novel Benzofuran-2-carboxylic Acids as Potent Pim-1 Inhibitors
- 3r02: The Discovery of Novel Benzofuran-2-carboxylic Acids as Potent Pim-1 Inhibitors
- 3r04: The Discovery of Novel Benzofuran-2-carboxylic Acids as Potent Pim-1 Inhibitors
- 3lcy: Titin Ig Tandem Domains A164-a165
- 3nlb: Novel Kinase Profile Highlights The Temporal Basis of Context Dependent Checkpoint Pathways to Cell Death
- 3psd: Non-oxime Pyrazole Based Inhibitors of B-raf Kinase
- 6xx9: Arabidopsis Thaliana Casein Kinase 2 (ck2) Alpha-1 Crystal Form III
- 6xx8: Arabidopsis Thaliana Casein Kinase 2 (ck2) Alpha-1 Crystal Form II
- 3r1n: Mk3 Kinase Bound to Compound 5b
- 6xx7: Arabidopsis Thaliana Casein Kinase 2 (ck2) Alpha-1 Crystal in Complex with Anp
- 6xx6: Arabidopsis Thaliana Casein Kinase 2 (ck2) Alpha-1 Crystal Form I
- 3r2b: Mk2 Kinase Bound to Compound 5b
- 3r2y: Mk2 Kinase Bound to Compound 1
- 3r30: Mk2 Kinase Bound to Compound 2
- 2kyl: Solution Structure of Mast2-pdz Complexed with The C-terminus of Pten
- 6ol2: Crystallography of Novel Wnk1 and Wnk3 Inhibitors Discovered from High-throughput-screening
- 6l54: Structure of Smg189
- 6l53: Structure of Smg1
- 6rff: Human Protein Kinase Ck2 Alpha in Complex with 2-cyano-2-propenamide Compound 7
- 6rfe: Human Protein Kinase Ck2 Alpha in Complex with 2-cyano-2-propenamide Compound 4
- 6rcm: Human Protein Kinase Ck2 Alpha in Complex with 2-cyano-2-propenamide Compound 3
- 6rcb: Human Protein Kinase Ck2 Alpha in Complex with 2-cyano-2-propenamide Compound 14
- 6rb1: Human Protein Kinase Ck2 Alpha in Complex with 2-cyano-2-propenamide Compound 1
- 6lnm: Crystal Structure of Cask-camk in Complex with Mint1-cid
- 6rsu: Tbk1 in Complex with Inhibitor Compound 35
- 6rch: Crystal Structure of Casein Kinase I Isoform Delta (ck1 Delta) Complexed with Sr4133 Inhibitor
- 6rcg: Crystal Structure of Casein Kinase 1 Delta (ck1 Delta) Complexed with Sr3029 Inhibitor
- 6qy8: Human CSNK2A2 Bound to Erb-041
- 6qy7: Human CSNK2A1 Bound to Erb-041
- 6y7c: Early Cytoplasmic Yeast Pre-40s Particle (purified with Tsr1 as Bait)
- 6l1z: Crystal Structure of CK2A1 with Hematein
- 6p5p: Discovery of a Novel, Highly Potent, and Selective Thieno[3,2- D]pyrimidinone-based Cdc7 Inhibitor with a Quinuclidine Moiety (tak- 931) as an Orally Active Investigational Anti-tumor Agent
- 6y6h: Crystal Structure of STK17B (drak2) in Complex with Unc-ap-194 Probe
- 6y6f: Crystal Structure of STK17B (drak2) in Complex with Pkis43
- 6vzh: Structure of Human Vaccinia-related Kinase 1 (vrk1) Bound to Ldsm311
- 3rcj: Rapid Preparation of Triazolyl Substituted Nh-heterocyclic Kinase Inhibitors via One-pot Sonogashira Coupling Tms-deprotection Cuaac Sequence
- 3rgx: Structural Insight into Brassinosteroid Perception by Bri1
- 3rgz: Structural Insight into Brassinosteroid Perception by Bri1
- 3riz: Crystal Structure of The Plant Steroid Receptor Bri1 Ectodomain
- 3rj0: Plant Steroid Receptor Bri1 Ectodomain in Complex with Brassinolide
- 3rps: Structure of Human CK2ALPHA in Complex with The Atp-competitive Inhibitor 3-(4,5,6,7-tetrabromo-1h-benzotriazol-1-yl)propan-1-ol
- 6u0k: Ttbk2 Kinase Domain in Complex with Compound 1
- 6ntd: Crystal Structure of G12V Hras-gppnhp Bound in Complex with The Engineered Rbd Variant 12 of Craf Kinase Protein
- 3s95: Crystal Structure of The Human Limk1 Kinase Domain in Complex with Staurosporine
- 3sdj: Structure of Rnase-inactive Point Mutant of Oligomeric Kinase/rnase Ire1
- 3sdm: Structure of Oligomeric Kinase/rnase Ire1 in Complex with an Oligonucleotide
- 6shc: Crystal Structure of Human Ire1 Luminal Domain Q105C
- 3r21: Design, Synthesis, and Biological Evaluation of Pyrazolopyridine- Sulfonamides as Potent Multiple-mitotic Kinase (mmk) Inhibitors (part I)
- 3r22: Design, Synthesis, and Biological Evaluation of Pyrazolopyridine- Sulfonamides as Potent Multiple-mitotic Kinase (mmk) Inhibitors (part I)
- 6rst: Tbk1 in Complex with Inhibitor Compound 24
- 6rsr: Tbk1 in Complex with Compound 2
- 3skc: Human B-raf Kinase in Complex with an Amide Linked Pyrazolopyridine Inhibitor
- 6nid: Crystal Structure of a Human Calcium/calmodulin Dependent Serine Protein Kinase (cask) Pdz Domain in Complex with Neurexin-1 Peptide
- 6nh9: Crystal Structure of a Human Calcium/calmodulin Dependent Serine Protein Kinase (cask) Pdz Domain
- 2yiq: Structural Analysis of Checkpoint Kinase 2 in Complex with Inhibitor Pv1322
- 2yir: Structural Analysis of Checkpoint Kinase 2 in Complex with Inhibitor Pv1352
- 2yit: Structural Analysis of Checkpoint Kinase 2 in Complex with Pv1162, a Novel Inhibitor
- 6k9l: 4.27 Angstrom Resolution Cryo-em Structure of Human Dimeric Atm Kinase
- 6k9k: Monomeric Human Atm (ataxia Telangiectasia Mutated) Kinase
- 3pe1: Crystal Structure of Human Protein Kinase Ck2 Alpha Subunit in Complex with The Inhibitor Cx-4945
- 3pe2: Crystal Structure of Human Protein Kinase Ck2 in Complex with The Inhibitor Cx-5011
- 5qqn: Pandda Analysis Group Deposition -- Crystal Structure of Kalirin/rac1 in Complex with Molport-010-382-606
- 5qqm: Pandda Analysis Group Deposition -- Crystal Structure of Kalirin/rac1 in Complex with Molport-009-565-325
- 5qql: Pandda Analysis Group Deposition -- Crystal Structure of Kalirin/rac1 in Complex with Molport-009-565-301
- 5qqk: Pandda Analysis Group Deposition -- Crystal Structure of Kalirin/rac1 in Complex with Molport-009-359-835
- 5qqj: Pandda Analysis Group Deposition -- Crystal Structure of Kalirin/rac1 in Complex with Molport-009-587-558
- 5qqi: Pandda Analysis Group Deposition -- Crystal Structure of Kalirin/rac1 in Complex with Molport-009-178-994
- 5qqh: Pandda Analysis Group Deposition -- Crystal Structure of Kalirin/rac1 in Complex with Molport-020-096-465
- 5qqg: Pandda Analysis Group Deposition -- Crystal Structure of Kalirin/rac1 in Complex with Molport-009-541-216
- 5qqf: Pandda Analysis Group Deposition -- Crystal Structure of Kalirin/rac1 in Complex with Molport-004-412-710
- 5qqe: Pandda Analysis Group Deposition -- Crystal Structure of Kalirin/rac1 in Complex with Molport-009-531-494
- 5qqd: Pandda Analysis Group Deposition -- Crystal Structure of Kalirin/rac1 in Complex with Z56880342
- 6uya: Crystal Structure of Compound 19 Bound to Irak4
- 6urc: Crystal Structure of IRE1A in Complex with Compound 18
- 6ul8: Rip2 Kinase Catalytic Domain Complex with (5s,6s,8r)-2- (benzo[d]thiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8- Methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide
- 3s1a: Crystal Structure of The Phosphorylation-site Double Mutant S431E/T432E of The Kaic Circadian Clock Protein
- 6uan: B-raf:14-3-3 Complex
- 6u2h: Braf Dimer Bound to 14-3-3
- 6u2g: Braf-mek Complex with Amp-pcp Bound to Braf
- 3amy: Crystal Structure of Human Ck2 Alpha Complexed with Apigenin
- 6szj: Rip2 Kinase Catalytic Domain Complex with 5AMINO1TERTBUTYL3(3METHOXYPHENYL)1H PYRAZOLE4CARBOXAMIDE.
- 6sze: Rip2 Kinase Catalytic Domain Complex with 5-amino-1-phenylpyrazole-4- Carboxamide.
- 3t9i: Pim1 Complexed with a Novel 3,6-disubstituted Indole at 2.6 Ang Resolution
- 3tac: Crystal Structure of The Liprin-alpha/cask Complex
- 3tku: Mrck Beta in Complex with Fasudil
- 3tv4: Human B-raf Kinase Domain in Complex with an Bromopyridine Benzamide Inhibitor
- 3tv6: Human B-raf Kinase Domain in Complex with a Methoxypyrazolopyridinyl Benzamide Inhibitor
- 6sl1: Structure of The Open Conformation of Cttel1
- 6sl0: Complete Cttel1 Dimer with C2 Symmetry
- 6skz: Structure of The Closed Conformation of Cttel1
- 6sky: Fat and Kinase Domain of Cttel1
- 3zut: The Structure of Ost1 (D160A) Kinase
- 3zuu: The Structure of Ost1 (D160A, S175D) Kinase in Complex with Gold
- 6sdb: Chimeric Titin Z1Z2 Functionalized with a Kler Exogenous Peptide from Decorin
- 6sb2: Cryo-em Structure of Mtorc1 Bound to Active Raga/c Gtpases
- 6sb0: Cryo-em Structure of Mtorc1 Bound to Pras40-fused Active Raga/c Gtpases
- 6s9x: Crystal Structure of Akt1 in Complex with Covalent-allosteric Akt Inhibitor 15c
- 6s9w: Crystal Structure of Akt1 in Complex with Covalent-allosteric Akt Inhibitor 16a
- 6s8f: Structure of Nucleotide-bound Tel1/atm
- 3p86: Crystal Structure of Ctr1 Kinase Domain Mutant D676N in Complex with Staurosporine
- 3sc1: Novel Isoquinolone Pdk1 Inhibitors Discovered through Fragment-based Lead Discovery
- 3si5: Kinetochore-bubr1 Kinase Complex
- 6s1f: Structure of The Kinase Domain of Human Ripk2 in Complex with The Inhibitor Cslp3
- 2xuu: Crystal Structure of a Dap-kinase 1 Mutant
- 3at2: Crystal Structure of CK2ALPHA
- 3at3: Crystal Structure of CK2ALPHA with Pyradine Derivative
- 3at4: Crystal Structure of CK2ALPHA with Pyradine Derivertive
- 3pwd: Crystal Structure of Maize Ck2 in Complex with Nbc (z1)
- 3t4n: Structure of The Regulatory Fragment of Saccharomyces Cerevisiae Ampk in Complex with Adp
- 3tdh: Structure of The Regulatory Fragment of Sccharomyces Cerevisiae Ampk in Complex with Amp
- 3te5: Structure of The Regulatory Fragment of Sacchromyces Cerevisiae Ampk in Complex with Nadh
- 6rna: Rip2 Kinase Catalytic Domain Complex with 2({4[(1,3BENZOTHIAZOL5YL) AMINO]6(2METHYLPROPANE2SULFONYL)QUINAZOLIN7YL}OXY)ETHAN1OL
- 6rn8: Rip2 Kinase Catalytic Domain Complex with 2(4[(1,3BENZOTHIAZOL5YL) AMINO]6(2METHYLPROPANE2SULFONYL)QUINAZOLIN7YL)OXY)ETHYL Phosphate
- 6rln: Crystal Structure of Rip1 Kinase in Complex with Gsk3145095
- 2ycf: Crystal Structure of Checkpoint Kinase 2 in Complex with Inhibitor Pv1531
- 2ycq: Crystal Structure of Checkpoint Kinase 2 in Complex with Inhibitor Pv1115
- 2ycr: Crystal Structure of Checkpoint Kinase 2 in Complex with Inhibitor Pv976
- 2ycs: Crystal Structure of Checkpoint Kinase 2 in Complex with Pv788
- 3rwp: Discovery of a Novel, Potent and Selective Inhibitor of 3- Phosphoinositide Dependent Kinase (pdk1)
- 3rwq: Discovery of a Novel, Potent and Selective Inhibitor of 3- Phosphoinositide Dependent Kinase (pdk1)
- 3tax: A Neutral Diphosphate Mimic Crosslinks The Active Site of Human O- Glcnac Transferase
- 3udb: Crystal Structure of Snrk2.6
- 6rfj: Irak4 in Complex with Inhibitor
- 6rfi: Irak4 in Complex with Inhibitor
- 6rbd: State 1 of Yeast Tsr1-tap Rps20-deltaloop Pre-40s Particles
- 2xzs: Death Associated Protein Kinase 1 Residues 1-312
- 6ra7: Human Tnik in Complex with Compound 9
- 2y0a: Structure of Dapk1 Construct Residues 1-304
- 3ppz: Crystal Structure of Ctr1 Kinase Domain in Complex with Staurosporine
- 3puc: Atomic Resolution Structure of Titin Domain M7
- 3pzh: Crystal Structure of Maize Ck2 Alpha in Complex with Emodin at 1.92 a Resolution
- 3q04: Crystal Structure of The Apo-form of Human Ck2 Alpha at Ph 8.5
- 3q4z: Structure of Unphosphorylated Pak1 Kinase Domain
- 3q52: Structure of Phosphorylated Pak1 Kinase Domain
- 3q53: Structure of Phosphorylated Pak1 Kinase Domain in Complex with Atp
- 3r0t: Crystal Structure of Human Protein Kinase Ck2 Alpha Subunit in Complex with The Inhibitor Cx-5279
- 6r5f: Crystal Structure of Rip1 Kinase in Complex with Dhp77
- 6r4d: Aurora-a in Complex with Shape-diverse Fragment 58
- 6r4c: Aurora-a in Complex with Shape-diverse Fragment 57
- 3she: Novel Atp-competitive Mk2 Inhibitors with Potent Biochemical and Cell- Based Activity throughout The Series
- 6r4b: Aurora-a in Complex with Shape-diverse Fragment 56
- 6r4a: Aurora-a in Complex with Shape-diverse Fragment 55
- 6r49: Aurora-a in Complex with Shape-diverse Fragment 39
- 6r1h: Crystal Structure of The Lrr Ectodomain of The Receptor Kinase Sobir1 from Arabidopsis Thaliana.
- 6qy9: Human CSNK2A2 Bound to a Pyrrolo[2,3-d]pyrimidinyl Inhibitor
- 3uc3: The Crystal Structure of Snf1-related Kinase 2.3
- 3uc4: The Crystal Structure of Snf1-related Kinase 2.6
- 6qxk: Human Pim1 Bound to Ox0999
- 4a06: Human Pdk1 Kinase Domain in Complex with Allosteric Activator Ps114 Bound to The Pif-pocket
- 4a07: Human Pdk1 Kinase Domain in Complex with Allosteric Activator Ps171 Bound to The Pif-pocket
- 6qsa: Cryogenic Temperature Structure of Blue Light-irradiated ATPHOT2LOV2 Recorded after an Accumulated Dose of 48 Kgy
- 6qs5: Crystal Structure of Maize Ck2 in Complex with Tyrphostin Ag99
- 6qqk: Room Temperature Structure of Blue Light-irradiated ATPHOT2LOV2 Recorded after an Accumulated Dose of 34 Kgy
- 6qqj: Room Temperature Structure of The Ground State of ATPHOT2LOV2 Recorded after an Accumulated Dose of 354 Kgy
- 6qqi: Cryogenic Temperature Structure of Blue Light-irradiated ATPHOT2LOV2 Recorded after an Accumulated Dose of 24 Kgy
- 6qqh: Cryogenic Temperature Structure of The Ground State of ATPHOT2LOV2 Recorded after an Accumulated Dose of 2.68 Mgy
- 2y4v: Crystal Structure of Human Calmodulin in Complex with a Dap Kinase-1 Mutant (W305Y) Peptide
- 6qn4: Death-associated Protein Kinase 1 (dapk1) Catalytic and Auto- Regulatory Domains with S289E and S308E Mutations
- 6qmo: Death-associated Protein Kinase 1 (dapk1) Catalytic and Auto- Regulatory Domains with S289E and S308A Mutations
- 4a55: Crystal Structure of P110ALPHA in Complex with Ish2 of P85ALPHA and The Inhibitor Pik-108
- 2ym3: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2ym4: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2ym5: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2ym6: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2ym7: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 2ym8: Crystal Structure of Checkpoint Kinase 1 (chk1) in Complex with Inhibitors
- 3q9w: Crystal Structure of Human Ck2 Alpha in Complex with Emodin at Ph 8.5
- 3q9x: Crystal Structure of Human Ck2 Alpha in Complex with Emodin at Ph 6.5
- 3q9y: Crystal Structure of Human Ck2 Alpha in Complex with Quinalizarin at Ph 8.5
- 3q9z: Crystal Structure of Human Ck2 Alpha in Complex with Quinalizarin at Ph 6.5
- 3qa0: Crystal Structure of The Apo-form of Human Ck2 Alpha at Ph 6.5
- 6qf4: X-ray Structure of Human Serine/threonine Kinase 17b (STK17B) Aka Drak2 in Complex with Adp Obtained by On-chip Soaking
- 3tl8: The Avrptob-bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains in a Single Type III Effector
- 3uys: Crystal Structure of Apo Human CK1D
- 3uyt: Crystal Structure of CK1D with Pf670462 from P1 Crystal Form
- 3uzp: Crystal Structure of CK1D with Pf670462 from P21 Crystal Form
- 2y4p: Dimeric Structure of Dapk-1 Catalytic Domain
- 6qav: Crystal Structure of Ulk2 in Complexed with Mrt68921
- 6qau: Crystal Structure of Ulk2 in Complexed with Mrt67307
- 6qat: Crystal Structure of Ulk2 in Complexed with Hesperadin
- 6qas: Crystal Structure of Ulk1 in Complexed with Pf-03814735
- 3qbn: Structure of Human Aurora a in Complex with a Diaminopyrimidine
- 3uv5: Crystal Structure of The Tandem Bromodomains of Human Transcription Initiation Factor Tfiid Subunit 1 (taf1)
- 2ydj: Discovery of Checkpoint Kinase Inhibitor Azd7762 by Structure Based Design and Optimization of Thiophene Carboxamide Ureas
- 6q4q: The Crystal Structure of CK2A Bound to P2-c4
- 6q38: The Crystal Structure of CK2A Bound to P1-c4
- 6q0t: Structure of a Mapk Pathway Complex
- 6q0k: Structure of a Mapk Pathway Complex
- 6q0j: Structure of a Mapk Pathway Complex
- 3u9n: X-ray Crystal Structure of Compound 1 Bound to Human Chk1 Kinase Domain
- 3unz: Aurora a in Complex with Rpm1679
- 3uo4: Aurora a in Complex with Rpm1680
- 3uo5: Aurora a in Complex with Yl1-038-31
- 3uo6: Aurora a in Complex with Yl5-083
- 3uod: Aurora a in Complex with Rpm1693
- 3uoh: Aurora a in Complex with Rpm1722
- 3uoj: Aurora a in Complex with Rpm1715
- 3uok: Aurora a in Complex with Yl5-81-1
- 3uol: Aurora a in Complex with So2-162
- 3up2: Aurora a in Complex with Rpm1686
- 3up7: Aurora a in Complex with Yl1-038-09
- 6pys: Human PI3KALPHA in Complex with Compound 2-10 ((3s)-3-benzyl-3-methyl- 5-[5-(2-methylpyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-1,3- Dihydro-2h-indol-2-one)
- 2lcs: Yeast NBP2P Sh3 Domain in Complex with a Peptide from STE20P
- 3q5o: Crystal Structure of Human Titin Domain M10
- 3ztx: Aurora Kinase Selective Inhibitors Identified Using a Taxol- Induced Checkpoint Sensitivity Screen.
- 6pp9: Crystal Structure of Braf:mek1 Complex
- 3v8s: Human Rho-associated Protein Kinase 1 (rock 1) in Complex with Indazole Derivative (compound 18)
- 2ygv: Conserved N-terminal Domain of The Yeast Histone Chaperone Asf1 in Complex with The C-terminal Fragment of Rad53
- 3qp3: Crystal Structure of Titin Domain M4, Tetragonal Form
- 3tv7: Human Rho-associated Protein Kinase 1 (rock 1) in Complex with Rki1342
- 3ujg: Crystal Structure of Snrk2.6 in Complex with Hab1
- 4a7c: Crystal Structure of Pim1 Kinase with Etp46546
- 6pk6: Human PRPF4B Bound to Benzothiophene Inhibitor 329
- 6pjj: Human PRPF4B Bound to Benzothiophene Inhibitor 224
- 4dit: Crystal Structure of GSK3BETA in Complex with a Imidazolopyridine Inhibitor
- 6pdp: Human Pim1 Bound to Benzothiophene Inhibitor 379
- 6pdo: Human Pim1 Bound to Benzothiophene Inhibitor 354
- 6pdn: Human Pim1 Bound to Benzothiophene Inhibitor 292
- 6pdi: Human Pim1 Bound to Benzothiophene Inhibitor 224
- 6pcw: Human Pim1 Bound to Benzothiophene Inhibitor 213
- 2y9q: Crystal Structure of Human Erk2 Complexed with a Mapk Docking Peptide
- 6p5s: Hipk2 Kinase Domain Bound to Cx-4945
- 4a1g: The Crystal Structure of The Human Bub1 Tpr Domain in Complex with The Ki Motif of Knl1
- 4afj: 5-aryl-4-carboxamide-1,3-oxazoles: Potent and Selective Gsk-3 Inhibitors
- 2yer: Synthesis and Evaluation of Triazolones as Checkpoint Kinase 1 Inhibitors
- 2yex: Synthesis and Evaluation of Triazolones as Checkpoint Kinase 1 Inhibitors
- 3uv4: Crystal Structure of The Second Bromodomain of Human Transcription Initiation Factor Tfiid Subunit 1 (taf1)
- 6oko: Crystal Structure of Mripk3 Complexed with N-(3-fluoro-4-{1h- Pyrrolo[2,3-b]pyridin-4-yloxy}phenyl)-1-(4-fluorophenyl)-2-oxo-1,2- Dihydropyridine-3-carboxamide
- 4daw: Crystal Structure of Pak1 Kinase Domain with The Ruthenium Phthalimide Complex
- 4dug: Crystal Structure of Circadian Clock Protein Kaic E318A Mutant
- 6ocq: Crystal Structure of Rip1 Kinase in Complex with a Pyrrolidine
- 3vbq: Exploitation of Hydrogen Bonding Constraints and Flat Hydrophobic Energy Landscapes in Pim-1 Kinase Needle Screening and Inhibitor Design
- 3vbt: Exploitation of Hydrogen Bonding Constraints and Flat Hydrophobic Energy Landscapes in Pim-1 Kinase Needle Screening and Inhibitor Design
- 3vbv: Exploitation of Hydrogen Bonding Constraints and Flat Hydrophobic Energy Landscapes in Pim-1 Kinase Needle Screening and Inhibitor Design
- 3vbw: Exploitation of Hydrogen Bonding Constraints and Flat Hydrophobic Energy Landscapes in Pim-1 Kinase Needle Screening and Inhibitor Design
- 3vbx: Exploitation of Hydrogen Bonding Constraints and Flat Hydrophobic Energy Landscapes in Pim-1 Kinase Needle Screening and Inhibitor Design
- 3vby: Exploitation of Hydrogen Bonding Constraints and Flat Hydrophobic Energy Landscapes in Pim-1 Kinase Needle Screening and Inhibitor Design
- 3vc4: Exploitation of Hydrogen Bonding Constraints and Flat Hydrophobic Energy Landscapes in Pim-1 Kinase Needle Screening and Inhibitor Design
- 6oac: Pqr530 [(s)-4-(difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino- 1,3,5-triazin-2-yl)pyridin-2-amine] Bound to The PI3KA Catalytic Subunit P110ALPHA
- 6o9d: Structure of The Irak4 Kinase Domain with Compound 5
- 6o95: Structure of The Irak4 Kinase Domain with Compound 41
- 6o94: Structure of The Irak4 Kinase Domain with Compound 17
- 6o8u: Crystal Structure of Irak4 in Complex with Compound 23
- 6o8c: Crystal Structure of Sting Ctt in Complex with Tbk1
- 6o8b: Crystal Structure of Sting Ctd in Complex with Tbk1
- 2ydi: Discovery of Checkpoint Kinase Inhibitor Azd7762 by Structure Based Design and Optimization of Thiophene Carboxamide Ureas
- 2ydk: Discovery of Checkpoint Kinase Inhibitor Azd7762 by Structure Based Design and Optimization of Thiophene Carboxamide Ureas
- 3axw: Crystal Structure of Human CK2ALPHA Complexed with a Potent Inhibitor
- 3tkh: Crystal Structure of Chk1 in Complex with Inhibitor S01
- 3tki: Crystal Structure of Chk1 in Complex with Inhibitor S25
- 3uix: Crystal Structure of Pim1 Kinase in Complex with Small Molecule Inhibitor
- 4af3: Human Aurora B Kinase in Complex with Incenp and Vx-680
- 4aot: Crystal Structure of Human Serine Threonine Kinase-10 (lok) Bound to GW830263A
- 4d9u: Rsk2 C-terminal Kinase Domain, (e)-tert-butyl 3-(4-amino-7-(3- Hydroxypropyl)-5-p-tolyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2- Cyanoacrylate
- 4dbn: Crystal Structure of The Kinase Domain of Human B-raf with a [1, 3]thiazolo[5,4-b]pyridine Derivative
- 6nyh: Structure of Human Ripk1 Kinase Domain in Complex with Gne684
- 6nyb: Structure of a Mapk Pathway Complex
- 6nw2: Structure of Human Ripk1 Kinase Domain in Complex with Compound 11
- 6nt9: Cryo-em Structure of The Complex between Human Tbk1 and Chicken Sting
- 3rny: Crystal Structure of Human Rsk1 C-terminal Kinase Domain
- 6nsq: Crystal Structure of Braf Kinase Domain Bound to The Inhibitor 2l
- 4a4x: Nek2-ede Bound to Cct248662
- 4afe: Nek2 Bound to Hybrid Compound 21
- 4apc: Crystal Structure of Human Nima-related Kinase 1 (nek1)
- 4d9t: Rsk2 C-terminal Kinase Domain with Inhibitor (e)-methyl 3-(4-amino-7- (3-hydroxypropyl)-5-p-tolyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2- Cyanoacrylate
- 6npz: Crystal Structure of Akt1 (aa 123-480) Kinase with a Bisubstrate
- 6npy: Cryo-em Structure of Nlrp3 Bound to Nek7
- 3re4: Crystal Structure of Archaeoglobus Fulgidus Rio1 Kinase Bound to Toyocamycin.
- 6npn: Crystal Structure of The Human Vaccinia-related Kinase Bound to a N,n- Dipropynyl-dihydropteridine-3-hydroxyindazole Inhibitor
- 6no9: Pim1 in Complex with Cpd16 (5-amino-n-(5-((4r,5r)-4-amino-5- Fluoroazepan-1-yl)-1-methyl-1h-pyrazol-4-yl)-2-(2,6-difluorophenyl) Thiazole-4-carboxamide)
- 6no8: Pim1 in Complex with Cpd9 ((r)-5-amino-n-(3-(4-aminoazepan-1-yl)-1h- Pyrazol-4-yl)-2-(2,6-difluorophenyl)thiazole-4-carboxamide)
- 3vap: Synthesis and Sar Studies of Imidazo-[1,2-a]-pyrazine Aurora Kinase Inhibitors with Improved off Target Kinase Selectivity
- 4anu: Complexes of PI3KGAMMA with Isoform Selective Inhibitors.
- 4anv: Complexes of PI3KGAMMA with Isoform Selective Inhibitors.
- 4anw: Complexes of PI3KGAMMA with Isoform Selective Inhibitors.
- 4anx: Complexes of PI3KGAMMA with Isoform Selective Inhibitors.
- 4aof: Selective Small Molecule Inhibitor Discovered by Chemoproteomic Assay Platform Reveals Regulation of Th17 Cell Differentiation by PI3KGAMMA
- 4dgl: Crystal Structure of The Ck2 Tetrameric Holoenzyme
- 4e26: Braf in Complex with an Organic Inhibitor 7898734
- 4e4x: Crystal Structure of B-raf Kinase Domain in Complex with a Dihydropyrido[2,3-d]pyrimidinone-based Inhibitor
- 6ng0: Crystal Structure of Hpk1 Kinase Domain T165E,S171E Phosphomimetic Mutant in Complex with Sunitinib in The Inactive State.
- 6nfz: Crystal Structure of Diphosphorylated Hpk1 Kinase Domain in Complex with Sunitinib in The Active State.
- 6nfy: Crystal Structure of Nonphosphorylated, Hpk1 Kinase Domain in Complex with Sunitinib in The Inactive State.
- 4acc: GSK3B in Complex with Inhibitor
- 4acd: GSK3B in Complex with Inhibitor
- 4acg: GSK3B in Complex with Inhibitor
- 4ach: GSK3B in Complex with Inhibitor
- 4dk5: Crystal Structure of Human PI3K-GAMMA in Complex with a Pyridyl- Triazine Inhibitor
- 4e7w: Structure of Gsk3 from Ustilago Maydis
- 4eep: Crystal Structure of Lov2 Domain of Arabidopsis Thaliana Phototropin 2
- 4eer: Crystal Structure of Lov2 Domain of Arabidopsis Thaliana Phototropin 2 C426A Mutant
- 4ees: Crystal Structure of Ilov
- 4eet: Crystal Structure of Ilov
- 4eeu: Crystal Structure of Philov2.1
- 6nct: Structure of P110ALPHA/NISH2 - Vector Data Collection
- 6ncg: Crystal Structure of Human Vaccinia-related Kinase 2 (vrk-2) Bound to Pyridin-benzenesulfonamide Inhibitor
- 2lru: Solution Structure of The Wnk1 Autoinhibitory Domain
- 3uim: Structural Basis for The Impact of Phosphorylation on Plant Receptor- like Kinase Bak1 Activation
- 5qu9: Pandda Analysis Group Deposition of Ground-state Model of Kalirin/rac1 Screened against a Customized Urea Fragment Library by X-ray Crystallography at The Xchem Facility of Diamond Light Source Beamline I04-1
- 4anm: Complex of Ck2 with a Cdc7 Inhibitor
- 4ejn: Crystal Structure of Autoinhibited Form of Akt1 in Complex with N-(4- (5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3h-imidazo[4,5- B]pyridin-3-yl)benzyl)-3-fluorobenzamide
- 4ekk: Akt1 with Amp-pnp
- 4ekl: Akt1 with Gdc0068
- 4eut: Structure of Bx-795 Complexed with Unphosphorylated Human Tbk1 Kinase- Uld Domain
- 4euu: Structure of Bx-795 Complexed with Human Tbk1 Kinase Domain Phosphorylated on Ser172
- 6n8g: Irak4 Bound to Benzoxazole Compound
- 2rse: Nmr Structure of Fkbp12-mtor Frb Domain-rapamycin Complex Structure Determined Based on Pcs
- 3u87: Structure of a Chimeric Construct of Human CK2ALPHA and Human CK2ALPHA' in Complex with a Non-hydrolysable Atp-analogue
- 3u9c: Structure of a C-terminal Deletion Mutant of Human Protein Kinase Ck2 Catalytic Subunit with The Atp-competitive Inhibitor Resorufin
- 6l20: Crystal Structure of CK2A2 with Hematein
- 6n45: Crystal Structure of The Cryptic Polo Box Domain of Human Activated Plk4 Variant 1
- 6n3o: Identification of Novel, Potent and Selective Gcn2 Inhibitors as First-in-class Anti-tumor Agents
- 6n3n: Identification of Novel, Potent and Selective Gcn2 Inhibitors as First-in-class Anti-tumor Agents
- 6n3l: Identification of Novel, Potent and Selective Gcn2 Inhibitors as First-in-class Anti-tumor Agents
- 6n0q: Braf in Complex with N-(4-methyl-3-(1-methyl-2-oxo-2,3-dihydro-1h- Benzo[d]imidazol-5-yl)phenyl)-3-(trifluoromethyl)benzamide.
- 6n0p: Braf in Complex with N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4- Yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide (lxh254)
- 6mzl: Human Tfiid Canonical State
- 6mzd: Human Tfiid Lobe a Canonical
- 4eai: Co-crystal Structure of an Ampk Core with Amp
- 4eaj: Co-crystal of Ampk Core with Amp Soaked with Atp
- 4eak: Co-crystal Structure of an Ampk Core with Atp
- 4eal: Co-crystal of Ampk Core with Atp Soaked with Amp
- 4aw2: Crystal Structure of Cdc42 Binding Protein Kinase Alpha (mrck Alpha)
- 6mt0: Crystal Structure of Human Pim-1 Kinase in Complex with a Quinazolinone-pyrrolodihydropyrrolone Inhibitor
- 6mom: Crystal Structure of Human Interleukin-1 Receptor Associated Kinase 4 (irak 4, Cid 100300) in Complex with Compound Ncc00371481 (bsi 107591)
- 6mnh: Ulk1 Unc-51 like Autophagy Activating Kinase in Complex with Inhibitor Btc
- 4efo: Crystal Structure of The Ubiquitin-like Domain of Human Tbk1
- 4f0f: Crystal Structure of The Roco4 Kinase Domain Bound to Appcp from D. Discoideum
- 4f0g: Crystal Structure of The Roco4 Kinase Domain from D. Discoideum
- 4f1m: Crystal Structure of The G1179S Roco4 Kinase Domain Bound to Appcp from D. Discoideum.
- 4f1t: Crystal Structure of The Roco4 Kinase Domain from D. Discoideum Bound to The Rock Inhibitor H1152
- 6mib: Crystal Structure of The Ilk Atp-binding Deficient Mutant (L207W) /alpha-parvin Core Complex
- 6mg9: Human Obscurin Ig57 Domain
- 4dhf: Structure of Aurora a Mutant Bound to Biogenidec Cpd 15
- 4dtk: Novel and Selective Pan-pim Kinase Inhibitor
- 4fhj: Crystal Structure of PI3K-GAMMA in Complex with Imidazopyridine 2
- 4fr4: Crystal Structure of Human Serine/threonine-protein Kinase 32a (yank1)
- 6mcq: L. Pneumophila Effector Kinase Legk7 in Complex with Human MOB1A
- 6mcp: L. Pneumophila Effector Kinase Legk7 (amp-pnp Bound) in Complex with Human MOB1A
- 3zxt: Dimeric Structure of Dapk-1 Catalytic Domain in Complex with Amppcp-mg
- 6qdr: Crystal Structure of 14-3-3sigma in Complex with a Pak6 Pt99 Phosphopeptide
- 6qds: Crystal Structure of 14-3-3sigma in Complex with a Pak6 Pt99 Phosphopeptide Stabilized by Semi-synthetic Fusicoccane Fc-ncpc
- 4dgm: Crystal Structure of Maize Ck2 in Complex with The Inhibitor Apigenin
- 4dgn: Crystal Structure of Maize Ck2 in Complex with The Inhibitor Luteolin
- 3umx: Crystal Structure of Pim1 Kinase in Complex with Inhibitor (z)-2-[(1h- Indol-3-yl)methylene]-7-(azepan-1-ylmethyl)-6-hydroxybenzofuran- 3(2h)-one
- 3uto: Twitchin Kinase Region from C.elegans (fn31-nl-kin-crd-ig26)
- 4enx: Crystal Structure of Pim-1 Kinase in Complex with Inhibitor (2e,5z)-2- (2-chlorophenylimino)-5-(4-hydroxy-3-nitrobenzylidene)thiazolidin-4- One
- 4eny: Crystal Structure of Pim-1 Kinase in Complex with (2e,5z)-2-(2- Chlorophenylimino)-5-(4-hydroxy-3-methoxybenzylidene)thiazolidin-4- One
- 4f1s: Crystal Structure of Human PI3K-GAMMA in Complex with a Pyridyl- Triazine-sulfonamide Inhibitor
- 4fk3: B-raf Kinase V600E Oncogenic Mutant in Complex with Plx3203
- 4g31: Crystal Structure of Gsk6414 Bound to Perk (r587-r1092, Delete A660- T867) at 2.28 a Resolution
- 4g34: Crystal Structure of Gsk6924 Bound to Perk (r587-r1092, Delete A660- T867) at 2.70 a Resolution
- 3tei: Crystal Structure of Human Erk2 Complexed with a Mapk Docking Peptide
- 3twj: Rho-associated Protein Kinase 1 (rock 1) in Complex with Rki1447
- 3u4u: Casein Kinase 2 in Complex with Az-inhibitor
- 4dea: Aurora a in Complex with Yl1-038-18
- 4deb: Aurora a in Complex with Rk2-17-01
- 4ded: Aurora a in Complex with Yl1-038-21
- 4dee: Aurora a in Complex with Adp
- 6jxc: Tel1 Kinase Butterfly Symmetric Dimer
- 6jxa: Tel1 Kinase Compact Monomer
- 6jwa: Crystal Structure of CK2A1 with 5-iodotubercidin
- 4fsm: Crystal Structure of The Chk1
- 4fsn: Crystal Structure of The Chk1
- 4fsq: Crystal Structure of The Chk1
- 4fsr: Crystal Structure of The Chk1
- 4fst: Crystal Structure of The Chk1
- 4fsu: Crystal Structure of The Chk1
- 4fsw: Crystal Structure of The Chk1
- 4fsy: Crystal Structure of The Chk1
- 4fsz: Crystal Structure of The Chk1
- 4ft0: Crystal Structure of The Chk1
- 4ft3: Crystal Structure of The Chk1
- 4ft5: Crystal Structure of The Chk1
- 4ft7: Crystal Structure of The Chk1
- 4ft9: Crystal Structure of The Chk1
- 4fta: Crystal Structure of The Chk1
- 4ftc: Crystal Structure of The Chk1
- 4fti: Crystal Structure of The Chk1
- 4ftj: Crystal Structure of The Chk1
- 4ftk: Crystal Structure of The Chk1
- 4ftl: Crystal Structure of The Chk1
- 4ftm: Crystal Structure of The Chk1
- 4ftn: Crystal Structure of The Chk1
- 4fto: Crystal Structure of The Chk1
- 4ftq: Crystal Structure of The Chk1
- 4ftr: Crystal Structure of The Chk1
- 4ftt: Crystal Structure of The Chk1
- 4ftu: Crystal Structure of The Chk1
- 4gb9: Potent and Highly Selective Benzimidazole Inhibitors of PI3K-DELTA
- 6jle: Crystal Structure of MORN4/MYO3A Complex
- 3ubd: Structure of N-terminal Domain of Rsk2 Kinase in Complex with Flavonoid Glycoside Sl0101
- 3uib: Map Kinase Lmampk10 from Leishmania Major in Complex with Sb203580
- 4aze: Human DYRK1A in Complex with Leucettine L41
- 4azf: Human Dyrk2 in Complex with Leucettine L41
- 4b9d: Crystal Structure of Human Nima-related Kinase 1 (nek1) with Inhibitor.
- 4el9: Structure of N-terminal Kinase Domain of Rsk2 with Afzelin
- 6j6i: Reconstitution and Structure of a Plant Nlr Resistosome Conferring Immunity
- 4ewh: Co-crystal Structure of Ack1 with Inhibitor
- 6j68: Structure of Kibra and Lats1 Complex
- 6j5v: Ligand-triggered Allosteric Adp Release Primes a Plant Nlr Complex
- 6j5u: Ligand-triggered Allosteric Adp Release Primes a Plant Nlr Complex
- 6j5t: Reconstitution and Structure of a Plant Nlr Resistosome Conferring Immunity
- 4fie: Full-length Human Pak4
- 4fif: Catalytic Domain of Human Pak4 with Rpkplvdp Peptide
- 4fig: Catalytic Domain of Human Pak4
- 4fih: Catalytic Domain of Human Pak4 with Qkftglprqw Peptide
- 4fii: Catalytic Domain of Human Pak4 with Rpkplvdp Peptide
- 4fij: Catalytic Domain of Human Pak4
- 4fj3: 14-3-3 Isoform Zeta in Complex with a Diphoyphorylated C-raf Peptide
- 4flh: Crystal Structure of Human PI3K-GAMMA in Complex with Amg511
- 3tpb: Structure of HIPA(S150A)
- 3tpd: Structure of Phipa, Monoclinic Form
- 3tpe: The Phipa P3121 Structure
- 3tpt: Structure of HIPA(D309Q) Bound to Adp
- 3tpv: Structure of Phipa Bound to Adp
- 3umw: Crystal Structure of Pim1 Kinase in Complex with Inhibitor (z)-2-[(1h- Indazol-3-yl)methylene]-6-methoxy-7-(piperazin-1-ylmethyl)benzofuran- 3(2h)-one
- 4a9r: Crystal Structure of Human Chk2 in Complex with Benzimidazole Carboxamide Inhibitor
- 4a9s: Crystal Structure of Human Chk2 in Complex with Benzimidazole Carboxamide Inhibitor
- 4a9t: Crystal Structure of Human Chk2 in Complex with Benzimidazole Carboxamide Inhibitor
- 4a9u: Crystal Structure of Human Chk2 in Complex with Benzimidazole Carboxamide Inhibitor
- 4as0: Cyclometalated Phthalimides as Protein Kinase Inhibitors
- 4aw0: Human Pdk1 Kinase Domain in Complex with Allosteric Compound Ps182 Bound to The Pif-pocket
- 4aw1: Human Pdk1 Kinase Domain in Complex with Allosteric Compound Ps210 Bound to The Pif-pocket
- 4bc6: Crystal Structure of Human Serine Threonine Kinase-10 Bound to Novel Bosutinib Isoform 1, Previously Thought to Be Bosutinib
- 6in4: Crystal Structure of Apo Dapk1 in The Presence of 18-crown-6
- 4fbx: Complex Structure of Human Protein Kinase Ck2 Catalytic Subunit Crystallized in The Presence of a Bisubstrate Inhibitor
- 4ful: Pi3 Kinase Gamma Bound to a Pyrmidine Inhibitor
- 4gh2: Crystal Structure of The Chk1
- 6t8x: Crystal Structure of Mapkapk2 (mk2) Complexed with Pf-3644022 and 5- (4-bromophenyl)-n-[4-(1-piperazinyl)phenyl]-n-(2-pyridinylmethyl)-2- Furancarboxamide
- 4gw8: Human Proto-oncogene Serine Threonine Kinase (pim1) in Complex with a Consensus Peptide and Leucettine L41
- 4f99: Human Cdc7 Kinase in Complex with Dbf4 and Nucleotide
- 4f9a: Human Cdc7 Kinase in Complex with Dbf4 and Nucleotide
- 4f9b: Human Cdc7 Kinase in Complex with Dbf4 and Pha767491
- 4f9c: Human Cdc7 Kinase in Complex with Dbf4 and Xl413
- 4fjy: Crystal Structure of PI3K-GAMMA in Complex with Quinoline-indoline Inhibitor 24f
- 4fjz: Crystal Structure of PI3K-GAMMA in Complex with Pyrrolo-pyridine Inhibitor 63
- 4gyw: Crystal Structure of Human O-glcnac Transferase in Complex with Udp and a Glycopeptide
- 4gyy: Crystal Structure of Human O-glcnac Transferase with Udp-5sglcnac and a Peptide Substrate
- 4gz3: Crystal Structure of Human O-glcnac Transferase with Udp and a Thioglycopeptide
- 6i2y: Human Stk10 Bound to Foretinib
- 6i2u: Aurora-a Kinase Domain in Complex with Coenzyme a
- 6i2p: Crystal Structure of The Mycobacterium Tuberculosis Pknb Kinase Domain (L33E Mutant) in Complex with Its Substrate Gara
- 6i0y: Tnac-stalled Ribosome Complex with The Titin I27 Domain Folding close to The Ribosomal Exit Tunnel
- 6hyo: Structure of Ulk1 Lir Motif Bound to Gabarap
- 3uiu: Crystal Structure of Apo-pkr Kinase Domain
- 3ulz: Crystal Structure of Apo Bak1
- 6hxf: Human Stk10 Bound to a Maleimide Inhibitor
- 6hx1: Ire1 Alpha in Complex with Imidazo[1,2-b]pyridazin-8-amine Compound 2
- 4equ: Human Stk-10 (lok) Kinase Domain in Dfg-out Conformation with Inhibitor Dsa-7
- 4g11: X-ray Structure of PI3K-GAMMA Bound to a 4-(morpholin-4-yl)- (6-oxo-1, 6-dihydropyrimidin-2-yl)amide Inhibitor
- 4g9c: Human B-raf Kinase Domain Bound to a Type II Pyrazolopyridine Inhibitor
- 4g9r: B-raf V600E Kinase Domain Bound to a Type II Dihydroquinazoline Inhibitor
- 4ggd: Structural Analysis of Human Cdc20 Supports Multisite Degron Recognition by Apc/c.
- 4hgl: Crystal Structure of CK1G3 with Compound 1
- 4hgs: Crystal Structure of CK1GS with Compound 13
- 4hgt: Crystal Structure of CK1D with Compound 13
- 4hnf: Crystal Structure of CK1D in Complex with Pf4800567
- 4hni: Crystal Structure of CK1E in Complex with Pf4800567
- 4hok: Crystal Structure of Apo CK1E
- 3zdi: Glycogen Synthase Kinase 3 Beta Complexed with Axin Peptide and Inhibitor 7d
- 3zhp: Human Mst3 (stk24) in Complex with MO25BETA
- 3zim: Discovery of a Potent and Isoform-selective Targeted Covalent Inhibitor of The Lipid Kinase PI3KALPHA
- 4alu: Benzofuropyrimidinone Inhibitors of Pim-1
- 4alv: Benzofuropyrimidinone Inhibitors of Pim-1
- 4b7t: Glycogen Synthase Kinase 3 Beta Complexed with Axin Peptide and Leucettine L4
- 4drh: Co-crystal Structure of The Ppiase Domain of Fkbp51, Rapamycin and The Frb Fragment of Mtor at Low Ph
- 4dri: Co-crystal Structure of The Ppiase Domain of Fkbp51, Rapamycin and The Frb Fragment of Mtor
- 4drj: O-crystal Structure of The Ppiase Domain of Fkbp52, Rapamycin and The Frb Fragment of Mtor
- 4gue: Structure of N-terminal Kinase Domain of Rsk2 with Flavonoid Glycoside Quercitrin
- 4gv1: Pkb Alpha in Complex with Azd5363
- 4h3p: Crystal Structure of Human Erk2 Complexed with a Mapk Docking Peptide
- 4h58: Braf in Complex with Compound 3
- 4hle: Compound 21 (1-alkyl-substituted 1,2,4-triazoles)
- 6hvd: Human Slk Bound to a Maleimide Inhibitor
- 6hv0: Ire1 Kinase/rnase in Complex with Imidazo[1,2-b]pyridazin-8-amine Compound 33
- 6hou: Human Protein Kinase Ck2 Alpha in Complex with Vanillin
- 6hot: Human Protein Kinase Ck2 Alpha in Complex with Ferulic Aldehyde
- 6hor: Human Protein Kinase Ck2 Alpha in Complex with Feruloylmethane
- 6hoq: Human Protein Kinase Ck2 Alpha in Complex with Ferulic Acid
- 6hop: Human Protein Kinase Ck2 Alpha in Complex with Curcumin Degradation Products
- 6hny: Human Protein Kinase Ck2 Alpha in Complex with Boldine
- 6hnw: Human Protein Kinase Ck2 Alpha in Complex with Coumestrol
- 6hmx: Rip2 Kinase Catalytic Domain Complex with N(4,5DIMETHYL1HPYRAZOL3YL) 7METHOXY6(2METHYLPROPANE2SULFONYL)QUINOLIN4AMINE
- 6hmr: Crystal Structure of Human Casein Kinase I Delta in Complex with a Photoswitchable 2-azothiazole-based Inhibitor (compound 2)
- 6hmp: Crystal Structure of Human Casein Kinase I Delta in Complex with a Photoswitchable 2-azoimidazole-based Inhibitor (compound 3)
- 4hzr: Crystal Structure of Ack1 Kinase Domain
- 6hme: Low-salt Structure of Protein Kinase Ck2 Catalytic Subunit (isoform CK2ALPHA; CSNK2A1 Gene Product) in Complex with The Indenoindole-type Inhibitor Thn27
- 4hzs: Crystal Structure of Ack1 Kinase Domain with C-terminal Sh3 Domain
- 6hmd: Structure of Protein Kinase Ck2 Catalytic Subunit (isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with The Indenoindole-type Inhibitor Ar18
- 6hmc: Structure of Protein Kinase Ck2 Catalytic Subunit (isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with The Indenoindole-type Inhibitor Thn27
- 6hmb: Structure of Protein Kinase Ck2 Catalytic Subunit (isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with The Inhibitor Cx-4945 (silmitasertib)
- 6hka: The Solution Structure of The Micelle-associated Fatc Domain of The Human Protein Kinase Ataxia Telangiectasia Mutated (atm)
- 6hk7: Crystal Structure of Gsk-3b in Complex with Pyrazine Inhibitor C50
- 6hk6: Human Riok2 Bound to Inhibitor
- 4id7: Ack1 Kinase in Complex with The Inhibitor Cis-3-[8-amino-1-(4- Phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanol
- 6hk4: Crystal Structure of Gsk-3b in Complex with Pyrazine Inhibitor C22
- 6hk3: Crystal Structure of Gsk-3b in Complex with Pyrazine Inhibitor C44
- 6pxn: Human Casein Kinase 1 Delta Tau Mutant (R178C)
- 6hjk: Crystal Structure of Aurora-a L210C Catalytic Domain in Complex with Asdo2
- 6hjj: Crystal Structure of Aurora-a L210C Catalytic Domain in Complex with Asdo6 Ligand
- 4ijm: Crystal Structure of Circadian Clock Protein Kaic A422V Mutant
- 6hho: Crystal Structure of Rip1 Kinase in Complex with Gsk547
- 6hhj: Crystal Structure of Akt1 in Complex with Covalent-allosteric Akt Inhibitor 24b
- 6hhg: Crystal Structure of Akt1 in Complex with Covalent-allosteric Akt Inhibitor 27
- 6hhf: Crystal Structure of Akt1 in Complex with Covalent-allosteric Akt Inhibitor Borussertib
- 6hci: Crystal Structure of Titin M3 Domain
- 6hbn: High-salt Structure of Protein Kinase Ck2 Catalytic Subunit (isoform CK2ALPHA/CSKN2A1 Gene Product) in Complex with The Indenoindole-type Inhibitor Thn27
- 3zon: Human Tyk2 Pseudokinase Domain Bound to a Kinase Inhibitor
- 6h4l: Structure of Titin M4 Trigonal Form
- 4b0g: Complex of Aurora-a Bound to an Imidazopyridine-based Inhibitor
- 6h0u: Glycogen Synthase Kinase-3 Beta (gsk3) Complex with a Covalent [1,2, 4]triazolo[1,5-a][1,3,5]triazine Inhibitor
- 6paw: Crystal Structure of Dapk2 S308A Calcium/calmodulin Complex
- 6gzm: Crystal Structure of Human Ckidelta with A86
- 6gzd: Crystal Structure of Human CSNK1A1 with A86
- 4ezj: Potent and Selective Inhibitors of PI3K-DELTA: Obtaining Isoform Selectivity from The Affinity Pocket and Tryptophan Shelf
- 4ezk: Potent and Selective Inhibitors of PI3K-DELTA: Obtaining Isoform Selectivity from The Affinity Pocket and Tryptophan Shelf
- 4ezl: Potent and Selective Inhibitors of PI3K-DELTA: Obtaining Isoform Selectivity from The Affinity Pocket and Tryptophan Shelf
- 4fa6: Design and Synthesis of a Novel Pyrrolidinyl Pyrido Pyrimidinone Derivative as a Potent Inhibitor of PI3KA and Mtor
- 4fad: Design and Synthesis of a Novel Pyrrolidinyl Pyrido Pyrimidinone Derivative as a Potent Inhibitor of PI3KA and Mtor
- 4fhk: Crystal Structure of PI3K-GAMMA in Complex with Imidazopyridazine 19e
- 4fza: Crystal Structure of Mst4-mo25 Complex
- 4fzd: Crystal Structure of Mst4-mo25 Complex with Wsf Motif
- 4fzf: Crystal Structure of Mst4-mo25 Complex with Dki
- 4geh: Crystal Structure of Mst4 Dimerization Domain Complex with Pdcd10
- 6gwm: Solution Structure of Rat Rip2 Caspase Recruitment Domain
- 6gvx: Crystal Structure of Maternal Embryonic Leucine Zipper Kinase (melk) in Complex with Dorsomorphin (compound C)
- 6gvi: Crystal Structure of PI3K Alpha in Complex with 3-(2-amino- Benzooxazol-5-yl)-1-isopropyl-1h-pyrazolo[3,4-d]pyrimidine-4,6- Diamine
- 6gvh: Crystal Structure of PI3K Alpha in Complex with 3-(2-amino- Benzooxazol-5-yl)-4-chloro-1-isopropyl-1h-pyrazolo[3,4-d]pyrimidin-6- Ylamine
- 6gvg: Crystal Structure of PI3K Alpha in Complex with 3-(2-amino- Benzooxazol-5-yl)-1-isopropyl-4-methyl-1h-pyrazolo[3,4-d]pyrimidin-6- Ylamine
- 6gvf: Crystal Structure of PI3K Alpha in Complex with 3-(2-amino- Benzooxazol-5-yl)-1-isopropyl-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine
- 4hyh: X-ray Crystal Structure of Compound 39 Bound to Human Chk1 Kinase Domain
- 4hyi: X-ray Crystal Structure of Compound 40 Bound to Human Chk1 Kinase Domain
- 6gtt: Human Stk10 Bound to Birb-796
- 4ib5: Structure of Human Protein Kinase Ck2 Catalytic Subunit in Complex with a CK2BETA-COMPETITIVE Cyclic Peptide
- 4im0: Structure of Tank-binding Kinase 1
- 4im2: Structure of Tank-binding Kinase 1
- 4im3: Structure of Tank-binding Kinase 1
- 6gro: Human CSNK1G3 Bound to Sb-223133
- 6gra: Human Aurka Bound to Brd-7880
- 6gr9: Human Aurkc Incenp Complex Bound to Vx-680
- 6gr8: Human Aurkc Incenp Complex Bound to Brd-7880
- 6gq7: PI3KG in Complex with Inh
- 4ith: Crystal Structure of Rip1 Kinase in Complex with Necrostatin-1 Analog
- 4iti: Crystal Structure of Rip1 Kinase in Complex with Necrostatin-3 Analog
- 4itj: Crystal Structure of Rip1 Kinase in Complex with Necrostatin-4
- 4iw0: Crystal Structure and Mechanism of Activation of Tbk1
- 4iwo: Crystal Structure and Mechanism of Activation of Tbk1
- 4iwp: Crystal Structure and Mechanism of Activation of Tbk1
- 4iwq: Crystal Structure and Mechanism of Activation of Tbk1
- 6gpv: Crystal Structure of Blue-light Irradiated Minisog
- 6gpu: Crystal Structure of Minisog at 1.17a Resolution
- 4j1r: Crystal Structure of GSK3B in Complex with Inhibitor 15r
- 4j71: Crystal Structure of GSK3B in Complex with Inhibitor 1r
- 6gn1: Crystal Structure of Glycogen Synthase Kinase-3 Beta (GSK3B) in Complex with Pik-75
- 4jg6: Rsk2 Ctd Bound to 2-cyano-3-(1h-indazol-5-yl)acrylamide
- 4jg7: Structure of Rsk2 Ctd Bound to 3-(3-(1h-pyrrolo[2,3-b]pyridine-3- Carbonyl)phenyl)-2-cyanoacrylamide
- 4jg8: Structure of Rsk2 T493M Ctd Mutant Bound to 2-cyano-n-(1-hydroxy-2- Methylpropan-2-yl)-3-(3-(3,4,5-trimethoxyphenyl)-1h-indazol-5-yl) Acrylamide
- 4jik: X-ray Crystal Structure of Compound 22a (r)-2-(4-chlorophenyl)-8- (piperidin-3-ylamino)imidazo[1,2-c]pyrimidine-5-carboxamide Bound to Human Chk1 Kinase Domain
- 6gmd: The Crystal Structure of CK2ALPHA in Complex with Compound 3
- 6gjo: Crystal Structure of Glycogen Synthase Kinase-3 Beta in Complex with Bi-91bs
- 4ehe: B-raf Kinase Domain in Complex with an Aminothienopyrimidine-based Inhibitor
- 4ehg: B-raf Kinase Domain in Complex with an Aminopyridimine-based Inhibitor
- 4iq6: Gsk-3beta with Inhibitor 6-chloro-n-cyclohexyl-4-(1h-pyrrolo[2,3- B]pyridin-3-yl)pyridin-2-amine
- 4jin: X-ray Crystal Structure of Archaeoglobus Fulgidus Rio1 Bound to (2e)- N-benzyl-2-cyano-3-(pyridine-4-yl)acrylamide (wp1086)
- 4bl1: Crystal Structure of Unphosphorylated Maternal Embryonic Leucine Zipper Kinase (melk) in Complex with Amp-pnp
- 6gih: Crystal Structure of CK2ALPHA with Cam187 Bound
- 6ggs: Structure of Rip2 Card Filament
- 6gfj: Structure of Rip2 Card Domain Fused to Crystallisable Mbp Tag
- 4jsn: Structure of Mtordeltan-mlst8 Complex
- 4jsp: Structure of Mtordeltan-mlst8-atpgammas-mg Complex
- 4jsv: Structure of Mtordeltan-mlst8-adp-mgf3-mg2 Complex
- 4jsx: Structure of Mtordeltan-mlst8-torin2 Complex
- 4jt5: Mtordeltan-mlst8-pp242 Complex
- 6spw: Structure of Protein Kinase Ck2 Catalytic Subunit with The CK2BETA- Competitive Bisubstrate Inhibitor Arc3140
- 6spx: Structure of Protein Kinase Ck2 Catalytic Subunit in Complex with The CK2BETA-COMPETITIVE Bisubstrate Inhibitor Arc1502
- 6g5i: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State R
- 6g51: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State D
- 6g4j: Structure of The Protein Kinase Yabt from Bacillus Subtilis in Complex with an Alpharep Crystallization Helper
- 6g3w: Crystal Structure of The Bir3 - Serk2 Complex from Arabidopsis Thaliana.
- 6g3a: Crystal Structure of Haspin F605T Mutant in Complex with 5- Iodotubercidin
- 6g39: Crystal Structure of Haspin F605Y Mutant in Complex with 5- Iodotubercidin
- 6g38: Crystal Structure of Haspin in Complex with Tubercidin
- 6g37: Crystal Structure of Haspin in Complex with 5-fluorotubercidin
- 6g36: Crystal Structure of Haspin in Complex with 5-chlorotubercidin
- 6g35: Crystal Structure of Haspin in Complex with 5-bromotubercidin
- 6g34: Crystal Structure of Haspin in Complex with 5-iodotubercidin
- 6g18: Cryo-em Structure of a Late Human Pre-40s Ribosomal Subunit - State C
- 6fwx: Chimeric Titin Z1Z2-Z1Z2 Tandem (z1212) Functionalized with a Grgds Exogenous Peptide from Fibronectin
- 4g16: Crystal Structure of CK1G3 with 2-[(4-{[3-(trifluoromethyl)pyridin2- Yl]oxy}phenyl)amino]-1h-benzimidazole-6-carbonitrile
- 4g17: Crystal Structure of CK1G3 with 2-[(4-tert-butylphenyl)amino]-1h- Benzimidazole-6-carbonitrile
- 6fvg: The Structure of CK2ALPHA with Cch507 Bound
- 6fvf: The Structure of CK2ALPHA with Cch503 Bound
- 6fu5: Structure of The Kinase Domain of Human Ripk2 in Complex with The Inhibitor Cslp18
- 4hq1: Crystal Structure of an Lrr Protein with Two Solenoids
- 4jai: Crystal Structure of Aurora Kinase a in Complex with N-{4-[(6-oxo-5,6- Dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide
- 4jaj: Crystal Structure of Aurora Kinase a in Complex with Benzo[c][1, 8]naphthyridin-6(5h)-one
- 4jbo: Novel Aurora Kinase Inhibitors Reveal Mechanisms of Hurp in Nucleation of Centrosomal and Kinetochore Microtubules
- 4jbp: Novel Aurora Kinase Inhibitors Reveal Mechanisms of Hurp in Nucleation of Centrosomal and Kinetochore Microtubules
- 4jbq: Novel Aurora Kinase Inhibitors Reveal Mechanisms of Hurp in Nucleation of Centrosomal and Kinetochore Microtubules
- 4jjr: A P21 Crystal Form of Mammalian Casein Kinase 1d with a Novel Dimer Interface.
- 4jvg: B-raf Kinase in Complex with Birb796
- 4k0y: Structure of Pim-1 Kinase Bound to N-(4-fluorophenyl)-7-hydroxy-5- (piperidin-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
- 4k18: Structure of Pim-1 Kinase Bound to 5-(4-cyanobenzyl)-n-(4- Fluorophenyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxamide
- 4k1b: Structure of Pim-1 Kinase Bound to N-(5-(2-fluorophenyl)-1h-pyrrolo[2, 3-b]pyridin-3-yl)-5-((((3r,4r)-3-fluoropiperidin-4-yl)methyl)amino) Pyrazolo[1,5-a]pyrimidine-3-carboxamide
- 6fih: Crystal Structure of The Anx2 Ectodomain from Arabidopsis Thaliana
- 6fig: Crystal Structure of The Anx1 Ectodomain from Arabidopsis Thaliana
- 6fif: Crystal Structure of The Bri1 Gly644-asp (bri1-6) Mutant from Arabidopsis Thaliana.
- 6fic: Bivalent Inhibitor Unc4512 Bound to The Taf1 Bromodomain Tandem
- 6fhb: Death-associated Protein Kinase 1 (dapk1) Catalytic and Auto- Regulatory Domains with S289A and S308E Mutations
- 6fha: Death-associated Protein Kinase 1 (dapk1) Catalytic and Auto- Regulatory Domains with S289A and S308A Mutations
- 6fh5: PI3KG in Complex with Compound 7
- 6fg8: Crystal Structure of The Bir3 - Serk1 Complex from Arabidopsis Thaliana.
- 4fi1: Crystal Structure of Scck2 Alpha in Complex with Atp
- 6fdz: Unc-51-like Kinase 3 (ulk3) in Complex with Momelotinib
- 6fdy: Unc-51-like Kinase 3 (ulk3) in Complex with Bosutinib
- 6fdo: Rio2 Structure
- 6fdn: Rio2 Structure
- 6fdm: Human Rio2 Kinase Structure
- 4jl9: Crystal Structure of Mouse Tbk1 Bound to Bx795
- 4jlc: Crystal Structure of Mouse Tbk1 Bound to Su6668
- 6fd3: Thiophosphorylated Pak3 Kinase Domain
- 6fck: Chk1 Kinase in Complex with Compound 13
- 6fcf: Chk1 Kinase in Complex with Compound 44
- 6fc8: Chk1 Kinase in Complex with Compound 13
- 4l0n: Crystal Structure of Stk3 (mst2) Sarah Domain
- 6fbk: Crystal Structure of The Human Wnk2 Cct-like 1 Domain in Complex with a Wnk1 Rfxv Peptide
- 6fai: Structure of a Eukaryotic Cytoplasmic Pre-40s Ribosomal Subunit
- 4bda: Fragment-based Screening Identifies a New Area for Inhibitor Binding to Checkpoint Kinase 2 (chk2)
- 4bdb: Fragment-based Screening Identifies a New Area for Inhibitor Binding to Checkpoint Kinase 2 (chk2)
- 4bdc: Fragment-based Screening Identifies a New Area for Inhibitor Binding to Checkpoint Kinase 2 (chk2)
- 4bdd: Fragment-based Screening Identifies a New Area for Inhibitor Binding to Checkpoint Kinase 2 (chk2)
- 4bde: Fragment-based Screening Identifies a New Area for Inhibitor Binding to Checkpoint Kinase 2 (chk2)
- 4bdf: Fragment-based Screening Identifies a New Area for Inhibitor Binding to Checkpoint Kinase 2 (chk2)
- 6fad: Sr Protein Kinase 1 (srpk1) in Complex with The Rgg-box of Hsv1 Icp27
- 4bdg: Fragment-based Screening Identifies a New Area for Inhibitor Binding to Checkpoint Kinase 2 (chk2)
- 4bdh: Fragment-based Screening Identifies a New Area for Inhibitor Binding to Checkpoint Kinase 2 (chk2)
- 4bdi: Fragment-based Screening Identifies a New Area for Inhibitor Binding to Checkpoint Kinase 2 (chk2)
- 4bdj: Fragment-based Screening Identifies a New Area for Inhibitor Binding to Checkpoint Kinase 2 (chk2)
- 4bdk: Fragment-based Screening Identifies a New Area for Inhibitor Binding to Checkpoint Kinase 2 (chk2)
- 4f2l: Structure of a Regulatory Domain of Ampk
- 6f7b: Crystal Structure of The Human Bub1 Kinase Domain in Complex with Bay 1816032
- 2m9x: Solution Nmr Structure of Microtubule-associated Serine/threonine- Protein Kinase 1 from Homo Sapiens, Northeast Structural Genomics Consortium (nesg) Target HR9151A
- 3w8h: Crystal Structure of Ccm3 in Complex with The C-terminal Regulatory Domain of Stk25
- 3w8i: Crystal Structure of Ccm3 in Complex with The C-terminal Regulatory Domain of Mst4
- 4b8l: Aurora B Kinase P353G Mutant
- 4b8m: Aurora B Kinase in Complex with Vx-680
- 6f3i: Irak4 in Complex with Inhibitor
- 6f3g: Irak4 in Complex with Inhibitor
- 6f3e: Irak4 in Complex with Inhibitor
- 6f3d: Irak4 in Complex with Inhibitor
- 6f26: Crystal Structure of Human Casein Kinase I Delta in Complex with Compound 31b
- 6f1w: Crystal Structure of Human Casein Kinase I Delta in Complex with Compound 31a
- 4g0n: Crystal Structure of Wt H-ras-gppnhp Bound to The Rbd of Raf Kinase
- 4g3x: Crystal Structure of Q61L H-ras-gppnhp Bound to The Rbd of Raf Kinase
- 6tlj: Cryo-em Structure of The Anaphase-promoting Complex/cyclosome, in Complex with The Mitotic Checkpoint Complex (apc/c-mcc) at 3.8 Angstrom Resolution
- 6tm5: Cryo-em Structure of The Anaphase-promoting Complex/cyclosome, in Complex with The NEK2A Substrate at 3.9 Angstrom Resolution
- 6s6q: Crystal Structure of The Lrr Ectodomain of The Plant Membrane Receptor Kinase Gassho1/schengen3 from Arabidopsis Thaliana in Complex with Casparian Strip Integrity Factor 2.
- 4kz0: Structure of PI3K Gamma with Imidazopyridine Inhibitors
- 4kzc: Structure of PI3K Gamma with Imidazopyridine Inhibitors
- 6es0: Crystal Structure of The Kinase Domain of Human Ripk2 in Complex with The Activation Loop Targeting Inhibitor Cs-r35
- 6eqi: Structure of Pink1 Bound to Ubiquitin
- 6eml: Cryo-em Structure of a Late Pre-40s Ribosomal Subunit from Saccharomyces Cerevisiae
- 6emk: Cryo-em Structure of Saccharomyces Cerevisiae Target of Rapamycin Complex 2
- 4j0m: Crystal Structure of Brl1 (lrr) in Complex with Brassinolide
- 6elm: Crystal Structure of The Human Wnk2 Cct1 Domain
- 4ksp: Crystal Structure of Human B-raf Bound to a Dfg-out Inhibitor Tak-632
- 4ksq: Crystal Structure of Human B-raf Bound to a Dfg-out Inhibitor 5b
- 6eim: Human Stk10 Bound to GW683134A
- 6eii: The Crystal Structure of CK2ALPHA in Complex with Compound 18
- 6ehu: The Crystal Structure of CK2ALPHA in Complex with Compound 32
- 6ehk: The Crystal Structure of CK2ALPHA in Complex with Cam4712 and Compound 37
- 6egf: Crystal Structure of The Inactive Unphosphorylated Irak4 Kinase Domain Bound to Amp-pnp
- 6ege: Crystal Structure of The Unphosphorylated Irak4 Kinase Domain Bound to a Type I Inhibitor
- 6egd: Crystal Structure of The Unphosphorylated Irak4 Kinase Domain Bound to a Type I Inhibitor
- 6ega: Irak4 in Complex with a Type II Inhibitor
- 6eg9: Irak4 in Complex with Ponatinib
- 6edx: Crystal Structure of Sgk3 Px Domain
- 6ed6: Crystal Structure of Rock2 with a Pyridinylbenzamide Based Inhibitor
- 6e9w: Crystal Structure of Rock1 with a Pyridinylbenzamide Based Inhibitor
- 6e4w: Structure of Ampk Bound to Activator
- 6e4u: Structure of Ampk Bound to Activator
- 6e4t: Structure of Ampk Bound to Activator
- 6dlp: Crystal Structure of Lrrk2 Wd40 Domain Dimer
- 6dlo: Crystal Structure of Lrrk2 Wd40 Domain Dimer
- 6dl4: Human Titin Zig10
- 6dd4: Crystal Structure of The Human Vaccinia-related Kinase Bound to a N,n- Dipropyl-dihydropteridine Inhibitor
- 6d8z: Crystal Structure of The C-terminal Guanine Exchange Factor Module of Human Trio
- 2rsv: Solution Structure of Human Full-length Vaccinia Related Kinase 1 (vrk1)
- 6p5m: Discovery of a Novel, Highly Potent, and Selective Thieno[3,2- D]pyrimidinone-based Cdc7 Inhibitor with a Quinuclidine Moiety (tak- 931) as an Orally Active Investigational Anti-tumor Agent
- 6d3l: Crystal Structure of Unphosphorylated Human Pkr
- 6d3k: Crystal Structure of Unphosphorylated Human Pkr Kinase Domain in Complex with Adp
- 3w10: Aurora Kinase a Complexed to Pyrazole Aminoquinoline I
- 3w16: Structure of Aurora Kinase a Complexed to Pyrazole-aminoquinoline Inhibitor III
- 3w18: Structure of Aurora Kinase a Complexed to Benzoimidazole-indazole Inhibitor XIII
- 3w2c: Structure of Aurora Kinase a Complexed to Benzoimidazole-indazole Inhibitor Xv
- 3w8l: Crystal Structure of Human Ck2 in Complex with Inositol Hexakisphosphate
- 3war: Crystal Structure of Human CK2A
- 6csw: Crystal Structure of The Human Vaccinia-related Kinase Bound to a N- Methyl-n-propyl-dihydropteridine Inhibitor
- 3we4: Crystal Structure of S6K1 Kinase Domain in Complex with a Pyrimidine Derivative Pf-4708671 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1- Yl]methyl}-5-(trifluoromethyl)-1h-benzimidazole
- 3we8: Pim-1 Kinase in Complex with Ruthenium-based Inhibitor
- 3wf5: Crystal Structure of S6K1 Kinase Domain in Complex with a Pyrazolopyrimidine Derivative 4-[4-(1h-benzimidazol-2-yl)piperidin-1- Yl]-1h-pyrazolo[3,4-d]pyrimidine
- 3wf6: Crystal Structure of S6K1 Kinase Domain in Complex with a Pyrazolopyrimidine Derivative 4-[4-(1h-indol-3-yl)-3,6- Dihydropyridin-1(2h)-yl]-1h-pyrazolo[3,4-d]pyrimidine
- 3wf7: Crystal Structure of S6K1 Kinase Domain in Complex with a Purine Derivative 1-(9h-purin-6-yl)-n-[3-(trifluoromethyl)phenyl]piperidine- 4-carboxamide
- 3wf8: Crystal Structure of S6K1 Kinase Domain in Complex with a Quinoline Derivative 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10- Tetrahydro-6h-cyclohepta[b]quinoline-11-carboxylate
- 3wf9: Crystal Structure of S6K1 Kinase Domain in Complex with a Quinoline Derivative 1-oxo-1-[(4-sulfamoylphenyl)amino]propan-2-yl-2-methyl-1, 2,3,4-tetrahydroacridine-9-carboxylate
- 6cqh: Crystal Structure of The Human Vaccinia-related Kinase Bound to a N- Propynyl-n-ethyl-dihydropteridine Inhibitor
- 6cqf: Crystal Structure of Hpk1 in Complex an Inhibitor G1858
- 6cqe: Crystal Structure of Hpk1 Kinase Domain S171A Mutant
- 6cqd: Crystal Structure of Hpk1 in Complex with Atp Analogue (amppnp)
- 6cq5: Tbk1 in Complex with Sulfone Analog of Amlexanox
- 6cq4: Tbk1 in Complex with Cyclohexyl Analog of Amlexanox
- 6cq0: Tbk1 in Complex with Dimethyl Amino Analog of Amlexanox
- 6cpg: Structure of Dephosphorylated Aurora a (122-403) in Complex with Inhibiting Monobody and At9283 in an Inactive Conformation
- 6cpf: Structure of Dephosphorylated Aurora a (122-403) Bound to Amppcp in an Active Conformation
- 6cpe: Structure of Apo, Dephosphorylated Aurora a (122-403) in an Active Conformation
- 3wi6: Crystal Structure of Mapkap Kinase-2 (mk2) in Complex with Non- Selective Inhibitor
- 3wik: Crystal Structure of The CK2ALPHA/COMPOUND10 Complex
- 3wil: Crystal Structure of The CK2ALPHA/COMPOUND3 Complex
- 6cnx: Crystal Structure of The Human Vaccinia-related Kinase 1 (vrk1) Bound to an N-propynyl-n-isopentyl-dihydropteridin Inhibitor
- 6cnh: Human PRPF4B in Complex with Rebastinib
- 6cn9: Crystal Structure of The Kinase Domain of Wnk1
- 6cmm: Crystal Structure of The Human Vaccinia-related Kinase Bound to a N,n- Dipropynyl-dihydropteridine Inhibitor
- 6cki: Co-crystal Structure of Mnk2 in Complex with Inhibitor
- 6ck6: Crystal Structure of MNK2-D228G in Complex with Inhibitor
- 6ck3: Co-crytsal Structure of Mnk2 in Complex with an Inhibitor
- 6cjy: Crystal Structure of MNK2-D228G in Complex with Inhibitor
- 6cjw: Crystal Structure of MNK2-D228G in Complex with Inhibitor
- 6cjh: Co-crystal Structure of Mnk2 in Complex with an Inhibitor
- 6cje: Crystal Structure of MNK2-D228G in Complex with Inhibitor
- 6cj5: Crystal Structure of MNK2-D228G in Complex with Inhibitor
- 6cfm: Crystal Structure of The Human Vaccinia-related Kinase Bound to a Propynyl-pteridinone Inhibitor
- 4b4l: Crystal Structure of an Ard Dap-kinase 1 Mutant
- 4bfm: The Crystal Structure of Mouse Pk38
- 4bky: Crystal Structure of Unphosphorylated Maternal Embryonic Leucine Zipper Kinase (melk) in Complex with Pyrrolopyrazole Inhibitor
- 4bkz: Crystal Structure of Unphosphorylated Maternal Embryonic Leucine Zipper Kinase (melk) in Complex with a Benzodipyrazole Inhibitor
- 4bl0: Crystal Structure of Yeast Bub3-bub1 Bound to Phospho-spc105
- 6ccy: Crystal Structure of Akt1 in Complex with a Selective Inhibitor
- 4bn1: Crystal Structure of V174M Mutant of Aurora-a Kinase
- 4btj: Ttbk1 in Complex with Atp
- 4btk: Ttbk1 in Complex with Inhibitor
- 4btm: Ttbk1 in Complex with Inhibitor
- 6cad: Crystal Structure of Raf Kinase Domain Bound to The Inhibitor 2a
- 6c9j: Amp-activated Protein Kinase Bound to Pharmacological Activator R734
- 6c9h: Non-phosphorylated Amp-activated Protein Kinase Bound to Pharmacological Activator R734
- 6c9g: Amp-activated Protein Kinase Bound to Pharmacological Activator R739
- 6c9f: Amp-activated Protein Kinase Bound to Pharmacological Activator R734
- 6c9d: Crystal Structure of Ka1-autoinhibited Mark1 Kinase
- 4byi: Aurora a Kinase Bound to a Highly Selective Imidazopyridine Inhibitor
- 4byj: Aurora a Kinase Bound to a Highly Selective Imidazopyridine Inhibitor
- 4bzn: Crystal Structure of Pim1 in Complex with a Pyrrolo(1,2-a) Pyrazinone Inhibitor
- 4bzo: Crystal Structure of Pim1 in Complex with a Pyrrolo- Pyrazinone Inhibitor
- 4c0t: Candida Albicans Pkh Kinase Domain
- 4c2v: Aurora B Kinase in Complex with The Specific Inhibitor Barasertib
- 4c2w: Crystal Structure of Aurora B in Complex with Amp-pnp
- 4c3p: Structure of Dephosphorylated Aurora a (122-403) Bound to Tpx2 and Amppcp
- 4c3r: Structure of Dephosphorylated Aurora a (122-403) Bound to Amppcp
- 4c4k: Crystal Structure of The Titin M10-obscurin Ig Domain 1 Complex
- 4c57: Structure of Gak Kinase in Complex with a Nanobody
- 4c58: Structure of Gak Kinase in Complex with Nanobody (nbgak_4)
- 4c59: Structure of Gak Kinase in Complex with Nanobody (nbgak_4)
- 4c8b: Structure of The Kinase Domain of Human Ripk2 in Complex with Ponatinib
- 4cfe: Structure of Full Length Human Ampk in Complex with a Small Molecule Activator, a Benzimidazole Derivative (991)
- 4cff: Structure of Full Length Human Ampk in Complex with a Small Molecule Activator, a Thienopyridone Derivative (a-769662)
- 4cfh: Structure of an Active Form of Mammalian Ampk
- 4ch9: Crystal Structure of The Human Klhl3 Kelch Domain in Complex with a Wnk4 Peptide
- 4chb: Crystal Structure of The Human Klhl2 Kelch Domain in Complex with a Wnk4 Peptide
- 4cqg: The Crystal Structure of Mpk38 in Complex with Otssp167, an Orally-administrative Melk Selective Inhibitor
- 4ct1: Human Pdk1-pkczeta Kinase Chimera in Complex with Allosteric Compound Ps315 Bound to The Pif-pocket
- 4ct2: Human Pdk1-pkczeta Kinase Chimera
- 4czt: Crystal Structure of The Kinase Domain of Snrk3.23 AT1G30270
- 4czu: Crystal Structure of The Kinase Domain of Snrk3.23 AT1G30270 T190D Mutant
- 4d28: Crystal Structure of The Kinase Domain of Snrk3.11 AT5G35410
- 4d2p: Structure of Melk in Complex with Inhibitors
- 4d2t: Structure of Melk in Complex with Inhibitors
- 4d2v: Structure of Melk in Complex with Inhibitors
- 4d2w: Structure of Melk in Complex with Inhibitors
- 4eqc: Crystal Structure of Pak1 Kinase Domain in Complex with Frax597 Inhibitor
- 4fc0: Crystal Structure of Human Kinase Domain of B-raf with a Dfg-out Inhibitor
- 4grb: Casein Kinase 2 (ck2) Bound to Inhibitor
- 4gub: Casein Kinase II Bound to Inhibitor
- 4hhd: 2.75 Angstrom Resolution Crystal Structure of The A. Thaliana Lov2 Domain with an Extended N-terminal A' Helix (cryo Dark Structure)
- 4hi8: Structure of Integrin-linked Kinase Ankyrin Repeat Domain in Complex with Pinch1 Lim1 Domain Collected at High Energy, Wavelength 0.32800
- 4hi9: 1.2 Structure of Integrin-linked Kinase Ankyrin Repeat Domain in Complex with Pinch1 Lim1 Domain Collected at Wavelength 0.91974
- 4hkd: Crystal Structure of Human Mst2 Sarah Domain
- 4hvb: Catalytic Unit of PI3KG in Complex with PI3K/MTOR Dual Inhibitor Pf- 04979064
- 4i41: Crystal Structure of Human Ser/thr Kinase Pim1 in Complex with Mitoxantrone
- 4i92: Structure of The Bsk8 Kinase Domain
- 4i93: Structure of The Bsk8 Kinase Domain (semet Labeled)
- 4i94: Structure of Bsk8 in Complex with Amp-pnp
- 4iaa: Crystal Structure of Ser/thr Kinase Pim1 in Complex with Thioridazine
- 4ian: Crystal Structure of Apo Human PRPF4B Kinase Domain
- 4iea: 14-3-3 Isoform Sigma in Complex with a Phosphorylated C-raf Peptide
- 4ifc: Crystal Structure of Adp-bound Human PRPF4B Kinase Domain
- 4ihl: Human 14-3-3 Isoform Zeta in Complex with a Diphoyphorylated C-raf Peptide and Cotylenin a
- 4iir: Crystal Structure of Amppnp-bound Human PRPF4B Kinase Domain
- 4ijp: Crystal Structure of Human PRPF4B Kinase Domain in Complex with 4-{5- [(2-chloro-pyridin-4-ylmethyl)-carbamoyl]-thiophen-2-yl}- Benzo[b]thiophene-2-carboxylic Acid Amine
- 4ixp: Crystal Structure of Maternal Embryonic Leucine Zipper Kinase (melk)
- 4j6i: Discovery of Thiazolobenzoxepin Pi3-kinase Inhibitors That Spare The Pi3-kinase Beta Isoform
- 4j8m: Aurora a in Complex with Cd532
- 4j8n: Aurora a Kinase Apo
- 4jdh: Crystal Structure of Serine/threonine-protein Kinase Pak 4 in Complex with Paktide T Peptide Substrate
- 4jdi: Crystal Structure of Serine/threonine-protein Kinase Pak 4 in Complex with Paktide S Peptide Substrate
- 4jdj: Crystal Structure of Serine/threonine-protein Kinase Pak 4 F461V Mutant in Complex with Paktide T Peptide Substrate
- 4jdk: Crystal Structure of Serine/threonine-protein Kinase Pak 4 F461V Mutant in Complex with Paktide S Peptide Substrate
- 4jnw: Bacterially Expressed Titin Kinase
- 4jps: Co-crystal Structures of The Lipid Kinase PI3K Alpha with Pan and Isoform Selective Inhibitors
- 4jqe: Crystal Structure of Scck2 Alpha in Complex with Amppn
- 4jr7: Crystal Structure of Scck2 Alpha in Complex with Gmppnp
- 4jx3: Crystal Structure of Pim1 Kinase
- 4jx7: Crystal Structure of Pim1 Kinase in Complex with Inhibitor 2-[(trans- 4-aminocyclohexyl)amino]-4-{[3-(trifluoromethyl) Phenyl]amino}pyrido[4,3-d]pyrimidin-5(6h)-one
- 6l21: Crystal Structure of CK2A1 H160A with Hematein
- 6l22: Crystal Structure of CK2A1 H115Y with Hematein
- 4kb8: CK1D in Complex with 1-{4-[3-(4-fluorophenyl)-1-methyl-1h-pyrazol-4- Yl]pyridin-2-yl}-n-methylmethanamine Ligand
- 4kba: CK1D in Complex with 9-[3-(4-fluorophenyl)-1-methyl-1h-pyrazol-4-yl]- 2,3,4,5-tetrahydropyrido[2,3-f][1,4]oxazepine Inhibitor
- 4kbc: CK1D in Complex with {4-[3-(4-fluorophenyl)-1h-pyrazol-4-yl]pyridin-2- Yl}methanol Inhibitor
- 4kbk: CK1D in Complex with (3s)-3-{4-[3-(4-fluorophenyl)-1-methyl-1h- Pyrazol-4-yl]pyridin-2-yl}morpholine Inhibitor
- 4ks7: Pak6 Kinase Domain in Complex with Pf-3758309
- 4ks8: Pak6 Kinase Domain in Complex with Sunitinib
- 4kwp: Crystal Structure of Human Ck2-alpha in Complex with a Benzimidazole Inhibitor (k164) at 1.25 a Resolution
- 4l1b: Crystal Structure of P110ALPHA Complexed with Nish2 of P85ALPHA
- 4l23: Crystal Structure of P110ALPHA Complexed with Nish2 of P85ALPHA and Pi-103
- 4l2y: Crystal Structure of P110ALPHA Complexed with Nish2 of P85ALPHA and Compound 9d
- 4l67: Crystal Structure of Catalytic Domain of Pak4
- 4l6q: Rock2 in Complex with Benzoxaborole
- 4lb5: Crystal Structure of Pkz Zalpha in Complex with Ds(cg)6 (hexagonal Form)
- 4lb6: Crystal Structure of Pkz Zalpha in Complex with Ds(cg)6 (tetragonal Form)
- 4lfi: Crystal Structure of Scck2 Alpha in Complex with Gmppnp
- 4lg4: Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by Rassf5
- 4lgd: Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by Rassf5
- 6v6l: Co-structure of Human Glycogen Synthase Kinase Beta with 1-(6-((2-((6- Amino-5-nitropyridin-2-yl)amino)ethyl)amino)-2-(2,4-dichlorophenyl) Pyridin-3-yl)-4-methylpiperazin-2-one
- 4ll5: Crystal Structure of Pim-1 in Complex with The Fluorescent Compound Skf86002
- 4lm5: Crystal Structure of Pim1 in Complex with 2-{4-[(3-aminopropyl) Amino]quinazolin-2-yl}phenol (resulting from Displacement of Skf86002)
- 4lmu: Crystal Structure of Pim1 in Complex with The Inhibitor Quercetin (resulting from Displacement of Skf86002)
- 4lqp: Crystal Structure of The CBK1(T743E)-MOB2 Kinase-coactivator Complex, in Crystal Form a
- 4lqq: Crystal Structure of The CBK1(T743E)-MOB2 Kinase-coactivator Complex in Crystal Form B
- 4lqs: Crystal Structure of The Cbk1-mob2 Kinase-coactivator Complex
- 4lrj: Bacterial Effector Nleh1 Kinase Domain with Amppnp and Mg2+
- 4lrk: Bacterial Effector Nleh2 Kinase Domain
- 4m66: Crystal Structure of The Mouse Rip3 Kinase Domain
- 4m69: Crystal Structure of The Mouse Rip3-mlkl Complex
- 4m7e: Structural Insight into Bl-induced Activation of The Bri1-bak1 Complex
- 4m7i: Crystal Structure of Gsk6157 Bound to Perk (r587-r1092, Delete A660- T867) at 2.34a Resolution
- 4m8t: Rsk2 T493M C-terminal Kinase Domain in Complex with 3-(3-(1h-pyrazol- 4-yl)phenyl)-2-cyanoacrylamide
- 4mao: Rsk2 T493M C-terminal Kinase Domain in Complex with Rmm58
- 4mbi: Discovery of Pyrazolo[1,5a]pyrimidine-based Pim1 Inhibitors
- 4mbj: Human B-raf Kinase Domain in Complex with an Imidazopyridine-based Inhibitor
- 4mbl: Discovery of Pyrazolo[1,5a]pyrimidine-based Pim1 Inhibitors
- 4md7: Crystal Structure of Full-length Symmetric Ck2 Holoenzyme
- 4md8: Crystal Structure of Full-length Symmetric Ck2 Holoenzyme with Mutated Alpha Subunit (F121E)
- 4md9: Crystal Structure of Symmetric Ck2 Holoenzyme with Mutated Alpha Subunit (F121E Truncated at Aa 336)
- 4mn8: Crystal Structure of Flg22 in Complex with The Fls2 and Bak1 Ectodomains
- 4mna: Crystal Structure of The Free Fls2 Ectodomains
- 4mne: Crystal Structure of The Braf:mek1 Complex
- 4mnf: Crystal Structure of BRAF-V600E Bound to Gdc0879
- 4mvf: Crystal Structure of Plasmodium Falciparum Cdpk2 Complexed with Inhibitor Staurosporine
- 4mwh: Crystal Structure of Scck2 Alpha in Complex with Atp
- 4n6y: Pim1 Complexed with a Phenylcarboxamide
- 4n6z: Pim1 Complexed with a Pyridylcarboxamide
- 4n70: Pim1 Complexed with a Pyridylcarboxamide
- 4neu: X-ray Structure of Receptor Interacting Protein 1 (rip1)kinase Domain with a 1-aminoisoquinoline Inhibitor
- 4nfm: Human Tau Tubulin Kinase 1 (ttbk1)
- 4nfn: Human Tau Tubulin Kinase 1 (ttbk1) Complexed with 3-({5-[(4-amino-4- Methylpiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}amino)- 5-bromophenol
- 4nh1: Crystal Structure of a Heterotetrameric Ck2 Holoenzyme Complex Carrying The Andante-mutation in CK2BETA and Consistent with Proposed Models of Autoinhibition and Trans-autophosphorylation
- 4nif: Heterodimeric Structure of Erk2 and Rsk1
- 4njd: Structure of P21-activated Kinase 4 with a Novel Inhibitor Ky-04031
- 4nkb: Crystal Structure of The Cryptic Polo Box (cpb)of Zyg-1
- 4nm0: Crystal Structure of Peptide Inhibitor-free Gsk-3/axin Complex
- 4nm3: Crystal Structure of Gsk-3/axin Complex Bound to Phosphorylated N- Terminal Auto-inhibitory Ps9 Peptide
- 4nr2: Crystal Structure of Stk4 (mst1) Sarah Domain
- 4nu1: Crystal Structure of a Transition State Mimic of The Gsk-3/axin Complex Bound to Phosphorylated N-terminal Auto-inhibitory Ps9 Peptide
- 4nus: Rsk2 N-terminal Kinase in Complex with Ljh685
- 4nw5: Rsk2 N-terminal Kinase in Complex with 2-amino-7-substituted Benzoxazole Compound 8
- 4nw6: Rsk2 N-terminal Kinase in Complex with 2-amino-7-substituted Benzoxazole Compound 27
- 4nxb: Crystal Structure of Ilov-i486(2lt) at Ph 7.0
- 4nxe: Crystal Structure of Ilov-i486(2lt) at Ph 6.5
- 4nxf: Crystal Structure of Ilov-i486(2lt) at Ph 8.0
- 4nxg: Crystal Structure of ILOV-I486Z(2LT) at Ph 9.0
- 4o0m: Crystal Structure of T. Elongatus Bp-1 Clock Protein Kaic
- 4o0r: Back Pocket Flexibility Provides Group-ii Pak Selectivity for Type 1 Kinase Inhibitors
- 4o0t: Back Pocket Flexibility Provides Group-ii Pak Selectivity for Type 1 Kinase Inhibitors
- 4o0v: Back Pocket Flexibility Provides Group-ii Pak Selectivity for Type 1 Kinase Inhibitors
- 4o0x: Back Pocket Flexibility Provides Group-ii Pak Selectivity for Type 1 Kinase Inhibitors
- 4o0y: Back Pocket Flexibility Provides Group-ii Pak Selectivity for Type 1 Kinase Inhibitors
- 4o38: Crystal Structure of The Human Cyclin G Associated Kinase (gak)
- 4obo: MAP4K4 in Complex with Inhibitor (compound 22), 6-(3-chlorophenyl) Quinazolin-4-amine
- 4obp: MAP4K4 in Complex with Inhibitor (compound 29), 6-(2-fluoropyridin-4- Yl)pyrido[3,2-d]pyrimidin-4-amine
- 4obq: MAP4K4 in Complex with Inhibitor (compound 31), N-[3-(4- Aminoquinazolin-6-yl)-5-fluorophenyl]-2-(pyrrolidin-1-yl)acetamide
- 4oh4: Crystal Structure of Bri1 in Complex with Bki1
- 4oh8: Crystal Structure of The Human Mst1-rassf5 Sarah Heterodimer
- 4oh9: Crystal Structure of The Human Mst2 Sarah Homodimer
- 4otm: Crystal Structure of The C-terminal Domain from Yeast Gcn2
- 4otn: Crystal Structure of The C-terminal Regulatory Domain of Murine Gcn2
- 4otp: Crystal Structure of The Catalytic Domain of The Human Riok1 Atypical Protein Kinase in Complex with Adp/mg2+
- 4ouc: Structure of Human Haspin in Complex with Histone H3 Substrate
- 5yks: Crystal Structure of Sucrose Nonfermenting-related Kinase (snrk)
- 5yh3: The Structure of HFAM20C and HFAM20A Complex
- 5yf9: Crystal Structure of CK2A2 Form-2
- 5yf4: A Kinase Complex Mst4-mob4
- 5y9m: Crystal Structure of CK2A2 Form 3
- 5y96: Crystal Structure of Anxur1 Extracellular Domain from Arabidopsis Thaliana
- 5y92: Crystal Structure of Anxur2 Extracellular Domain from Arabidopsis Thaliana
- 4p7i: Crystal Structure of The Merlin Ferm/dcaf1 Complex
- 4p90: Crystal Structure of The Kinase Domain of Human Pak1 in Complex with Compound 15
- 5y80: Complex Structure of Cyclin G-associated Kinase with Gefitinib
- 5y7z: Complex Structure of Cyclin G-associated Kinase with Gefitinib
- 4pf4: 1.1a X-ray Structure of The Apo Catalytic Domain of Death-associated Protein Kinase 1, Aa 1-277
- 5y3r: Cryo-em Structure of Human Dna-pk Holoenzyme
- 4pl3: Crystal Structure of Murine Ire1 in Complex with Mkc9989 Inhibitor
- 4pl4: Crystal Structure of Murine Ire1 in Complex with Oicr464 Inhibitor
- 4pl5: Crystal Structure of Murine Ire1 in Complex with Oicr573 Inhibitor
- 5xy9: Structure of The Mst4 and 14-3-3 Complex
- 4pp7: Highly Potent and Selective 3-n-methylquinazoline-4(3h)-one Based Inhibitors of B-RAFV600E Kinase
- 4prj: Aurora a Kinase Domain with Compound 2 (n-[1-(3-cyanobenzyl)-1h- Pyrazol-4-yl]-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide)
- 4ps3: Structure of PI3K Gamma in Complex with 1-[6-(5-methoxypyridin-3-yl)- 1,3-benzothiazol-2-yl]-3-[2-(1-propyl-1h-imidazol-4-yl)ethyl]urea
- 4ps7: Structure of PI3K Gamma in Complex with N-[6-(pyridin-3-yl)-1,3- Benzothiazol-2-yl]acetamide
- 5xvu: Crystal Structure of The Protein Kinase Ck2 Catalytic Domain from Plasmodium Falciparum Bound to Atp
- 4ps8: Structure of PI3K Gamma in Complex with N-[6-(5,6-dimethoxypyridin-3- Yl)-1,3-benzothiazol-2-yl]acetamide
- 5xvg: Crystal Structure of Pak4 in Complex with Inhibitor Czh226
- 5xvf: Crystal Structure of Pak4 in Complex with Inhibitor Czh062
- 5xva: Crystal Structure of Pak4 in Complex with Inhibitor Czh216
- 5xqz: Structure of The Mob1-ndr2 Complex
- 4pwn: Crystal Structure of Active Wnk1 Kinase
- 4pxw: Crystal Structure of Human Dcaf1 Wd40 Repeats (Q1250L)
- 4q2a: Wnk1: a Chloride Sensor via Autophosphorylation
- 5xlm: Monomer Form of M.tuberculosis Pkni Sensor Domain
- 5xll: Dimer Form of M. Tuberculosis Pkni Sensor Domain
- 4q5j: Crystal Structure of Semet Derivative Bri1 in Complex with Bki1
- 5xkn: Crystal Structure of Plant Receptor Erl2 in Complexe with Epfl4
- 5xkj: Crystal Structure of Plant Receptor Erl1-tmm in Complexe with Epf2
- 5xka: Crystal Structure of M.tuberculosis Pkni Kinase Domain
- 5xjx: Pre-formed Plant Receptor Erl1-tmm Complex
- 5xjo: Plant Receptor Erl1-tmm in Complex with Peptide Epf1
- 5xgj: Crystal Structure of PI3K Complex with an Inhibitor
- 5xgi: Crystal Structure of PI3K Complex with an Inhibitor
- 5xgh: Crystal Structure of PI3K Complex with an Inhibitor
- 4qfg: Structure of Ampk in Complex with Staurosporine Inhibitor and in The Absence of a Synthetic Activator
- 4qfr: Structure of Ampk in Complex with Cl-a769662 Activator and Staurosporine Inhibitor
- 4qfs: Structure of Ampk in Complex with BR2-A769662CORE Activator and Staurosporine Inhibitor
- 5x6o: Intact Atr/mec1-atrip/ddc2 Complex
- 5x18: Crystal Structure of Casein Kinase I Homolog 1
- 5x17: Crystal Structure of Murine CK1D in Complex with Adp
- 5wnm: Crystal Structure of Murine Receptor-interacting Protein 4 (ripk4) D143N Bound to Tozasertib (vx-680)
- 5wnl: Crystal Structure of Murine Receptor-interacting Protein 4 (ripk4) D143N Bound to Staurosporine
- 5wnk: Crystal Structure of Murine Receptor-interacting Protein 4 (ripk4) D143N Bound to Tg100-115
- 5wnj: Crystal Structure of Murine Receptor-interacting Protein Kinase 4 (ripk4) D143N in Complex with Lestaurtinib
- 5wni: Crystal Structure of Murine Receptor-interacting Protein Kinase 4 (ripk4) D143N in Complex with Atp
- 5wnh: X-ray Co-structure of Rho-associated Protein Kinase (rock1) with a Highly Selective Inhibitor
- 5wng: X-ray Co-structure of Rho-associated Protein Kinase (rock1) with a Highly Selective Inhibitor
- 5wnf: X-ray Co-structure of Rho-associated Protein Kinase (rock1) with a Highly Selective Inhibitor
- 5wne: X-ray Co-structure of Rho-associated Protein Kinase (rock1) with a Highly Selective Inhibitor
- 5wls: Crystal Structure of a Pollen Receptor Kinase 3
- 5we8: Crystal Structure of Wnk1 in Complex with N-{(3r)-1-[(4-chlorophenyl) Methyl]pyrrolidin-3-yl}-2-(3-methoxyphenyl)-n-methylquinoline-4- Carboxamide (compound 8)
- 5wdy: Crystal Structure of Wnk1 in Complex with 1-cyclohexyl-n-({6-fluoro-1- [2-(3-methoxyphenyl)pyridin-4-yl]-1h-indol-3-yl}methyl)methanamine (compound 6)
- 5wby: Crystal Structure of Mtor(deltan)-mlst8-pras40(beta-strand) Complex
- 5wbu: Crystal Structure of Mtor(deltan)-mlst8-pras40(alpha-helix & Beta- Strand) Complex
- 5wbk: Crystal Structure of The Arabidopsis Thaliana Raptor in Complex with The Tos Peptide of Human S6K1
- 5wbh: Structure of The Frb Domain of Mtor Bound to a Substrate Recruitment Peptide of S6K1
- 5w85: Crystal Structure of Irak-4 with a 4,6-diaminonicotinamide Inhibitor (compound Number 9)
- 5w84: Crystal Structure of Irak-4 with a 4,6-diaminonicotinamide Inhibitor (compound Number 4)
- 5w7t: Structure of Phosphorylated Wnk1
- 5w5v: Tbk1 Co-crystal Structure with Amlexanox
- 5w5q: MAP4K4 in Complex with Inhibitor Compound 12 (n3-methyl-10-(3-methyl- 3-(5-methyloxazol-2-yl)but-1-yn-1-yl)-6,7-dihydro-5h-5,7- Methanobenzo[c]imidazo[1,2-a]azepine-2,3-dicarboxamide)
- 5w5o: Identification of Potent and Selective Ripk2 Inhibitors for The Treatment of Inflammatory Diseases.
- 5w4w: Identification and Profiling of a Selective and Brain Penetrant Radioligand for in Vivo Target Occupancy Measurement of Casein Kinase 1 (ck1) Inhibitors
- 5w1r: Cryo-em Structure of Dnapkcs
- 4qox: Crystal Structure of Cdpk4 from Plasmodium Falciparum, PF3D7_0717500
- 4qpm: Structure of Bub1 Kinase Domain
- 5vyk: Crystal Structure of The Brs Domain of Braf in Complex with The Cc-sam Domain of Ksr1
- 4qtc: Structure of Human Haspin (gsg2) in Complex with Sch772984 Revealing The First Type-i Binding Mode
- 4r8q: Structure and Substrate Recruitment of The Human Spindle Checkpoint Kinase Bub1
- 5vuc: Pim1 Kinase in Complex with a Benzofuranone Inhibitor
- 5vub: Pim1 Kinase in Complex with a Benzofuranone Inhibitor
- 5vua: Pim1 Kinase in Complex with a Benzofuranone Inhibitor
- 6kzi: Crystal Structure of Ser/thr Kinase Pim1 in Complex with Thioridazine Derivatives
- 4rgj: Apo Crystal Structure of Cdpk4 from Plasmodium Falciparum, PF3D7_0717500
- 5vr3: Crystal Structure of The Brs Domain of Braf
- 4tpt: Crystal Structure of The Human Limk2 Kinase Domain in Complex with a Non-atp Competitive Inhibitor
- 4tuu: Isolated P110A Subunit of PI3KA Provides a Platform for Structure- Based Drug Design
- 4tv3: Isolated P110A Subunit of PI3KA Provides a Platform for Structure- Based Drug Design
- 4tw9: Difluoro-dioxolo-benzoimidazol-benzamides as Potent Inhibitors of CK1DELTA and Epsilon with Nanomolar Inhibitory Activity on Cancer Cell Proliferation
- 4twc: 2-benzamido-n-(1h-benzo[d]imidazol-2-yl)thiazole-4- Carboxamide Derivatives as Potent Inhibitors of CK1D/E
- 4txc: Crystal Structure of Dapk1 Kinase Domain in Complex with a Small Molecule Inhibitor
- 5vja: Crystal Structure of Human Zipper-interacting Protein Kinase (zipk, Alias Dapk3) in Complex with a Pyrazolo[3,4-d]pyrimidinone Ligand (hs38)
- 4u43: MAP4K4 in Complex with Inhibitor (compound 6)
- 4u44: MAP4K4 in Complex with Inhibitor (compound 16)
- 4u45: MAP4K4 in Complex with Inhibitor (compound 25)
- 4u6r: Crystal Structure of Human Ire1 Cytoplasmic Domains in Complex with a Sulfonamide Inhibitor.
- 4u97: Crystal Structure of Asymmetric Irak4 Dimer
- 4u9a: Sulphur Anomalous Crystal Structure of Asymmetric Irak4 Dimer
- 4uak: Mrck Beta in Complex with Adp
- 4ual: Mrck Beta in Complex with Bdp00005290
- 5vef: Pak4 Kinase Domain in Complex with Fasudil
- 5vee: Pak4 Kinase Domain in Complex with Frax486
- 5ved: Pak4 Kinase Domain in Complex with Staurosporine
- 4ump: Structure of Melk in Complex with Inhibitors
- 4umq: Structure of Melk in Complex with Inhibitors
- 4umr: Structure of Melk in Complex with Inhibitors
- 4umt: Structure of Melk in Complex with Inhibitors
- 4umu: Structure of Melk in Complex with Inhibitors
- 5vd3: Crystal Structure of Human Myt1 Kinase Domain (de-phosphorylated) in Complex with Saracatinib
- 5vd1: Crystal Structure of Human Myt1 Kinase Domain in Complex with Pha- 848125
- 5vd0: Crystal Structure of Human Myt1 Kinase Domain in Complex with Mk1775
- 5vcz: Crystal Structure of Human Myt1 Kinase Domain in Complex with Bosutinib Isomer
- 5vcy: Crystal Structure of Human Myt1 Kinase Domain in Complex with Bosutinib
- 5vcx: Crystal Structure of Human Myt1 Kinase Domain (untreated) in Complex with Saracatinib
- 5vcw: Crystal Structure of Human Myt1 Kinase Domain in Complex with Pelitinib
- 5vcv: Crystal Structure of Human Myt1 Kinase Domain in Complex with Dasatinib
- 5vam: Braf in Complex with Raf709
- 5val: Braf in Complex with N-(3-(tert-butyl)phenyl)-4-methyl-3-(6- Morpholinopyrimidin-4-yl)benzamide
- 4urk: PI3KG in Complex with Azd6482
- 5v82: Pim1 Kinase in Complex with Cpd17 (1-(6-(4,4-difluoropiperidin-3-yl) Pyridin-2-yl)-6-(6-methylpyrazin-2-yl)-1h-pyrazolo[4,3-c]pyridine)
- 5v80: Pim1 Kinase in Complex with Cpd1 (1-methyl-4-(3-(6-(piperazin-1-yl) Pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridin-5-yl)piperazin-2-one)
- 4uyn: Sar156497 an Exquisitely Selective Inhibitor of Aurora Kinases
- 4uzd: Sar156497 an Exquisitely Selective Inhibitor of Aurora Kinases
- 4uzh: Sar156497 an Exquisitely Selective Inhibitor of Aurora Kinases
- 5v62: Phospho-erk2 Bound to Bivalent Inhibitor Sbp3
- 5v61: Phospho-erk2 Bound to Bivalent Inhibitor Sbp2
- 4w7p: Crystal Structure of Rock 1 Bound to Yb-15-qd37
- 4w9w: Crystal Structure of Bmp-2-inducible Kinase in Complex with Small Molecule Azd-7762
- 4w9x: Crystal Structure of Bmp-2-inducible Kinase in Complex with Baricitinib
- 5uzj: Crystal Structure of Rock1 Bound to an Aminopyridine Inhibitor
- 4wsq: Crystal Structure of Adaptor Protein 2 Associated Kinase (aak1) in Complex with Small Molecule Inhibitor
- 5uvf: Crystal Structure of The Human Vaccinia-related Kinase Bound to Bi- D1870
- 5uu1: Crystal Structure of Human Vaccinia-related Kinase 2 (vrk-2) Bound to Bi-d1870
- 4nzw: Crystal Structure of Stk25-mo25 Complex
- 4o27: Crystal Structure of Mst3-mo25 Complex with wif Motif
- 4rgw: Crystal Structure of a Taf1-taf7 Complex in Human Transcription Factor Iid
- 5upl: Cdc42 Binds Pak4 via an Extended Gtpase-effector Inteface - 2 Peptide: PAK4FL, Cdc42 - Unrefined
- 5upk: Cdc42 Binds Pak4 via an Extended Gtpase-effector Interface - 3 Peptide: PAK4CAT, Pak4-n45, Cdc42
- 4wo5: Crystal Structure of a Braf Kinase Domain Monomer
- 5ul1: The Co-structure of 3-amino-6-(4-((1-(dimethylamino)propan-2-yl) Sulfonyl)phenyl)-n-phenylpyrazine-2-carboxamide and a Rationally Designed PI3K-ALPHA Mutant That Mimics Atr
- 5ukj: The Co-structure of N,n-dimethyl-4-[(6r)-6-methyl-5-(1h-pyrrolo[2,3- B]pyridin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5- A]pyrazin-3- Yl]benzenesulfonamide and a Rationally Designed PI3K-ALPHA Mutant That Mimics Atr
- 5ukf: Crystal Structure of The Human Vaccinia-related Kinase 1 Bound to an Oxindole Inhibitor
- 5uke: Nmr Structure of Monomeric Human Irak-m Death Domain R56D, Y61E Mutant
- 4o0s: Crystal Structures of Human Kinase Aurora a
- 4o0u: Crystal Structures of Human Kinase Aurora a
- 4o0w: Crystal Structures of Human Kinase Aurora a
- 5uk8: The Co-structure of (r)-4-(6-(1-(cyclopropylsulfonyl)cyclopropyl)-2- (1h-indol-4-yl)pyrimidin-4-yl)-3-methylmorpholine and a Rationally Designed PI3K-ALPHA Mutant That Mimics Atr
- 4qye: Chk1 Kinase Domain in Complex with Diarylpyrazine Compound 1
- 4qyf: Chk1 Kinase Domain in Complex with Aminopyrazine Compound 13
- 4qyg: Chk1 Kinase Domain in Complex with Diazacarbazole Compound 14
- 4qyh: Chk1 Kinase Domain in Complex with Diazacarbazole Gne-783
- 5uiu: Crystal Structure of Irak4 in Complex with Compound 30
- 5uit: Crystal Structure of Irak4 in Complex with Compound 14
- 5uis: Crystal Structure of Irak4 in Complex with Compound 12
- 5uir: Crystal Structure of Irak4 in Complex with Compound 11
- 5uiq: Crystal Structure of Irak4 in Complex with Compound 9
- 5ufu: Structure of Ampk Bound to Activator
- 5u94: Crystal Structure of The Mycobacterium Tuberculosis Pasta Kinase Pknb in Complex with The Potential Theraputic Kinase Inhibitor Gsk690693.
- 5u7r: Identification of a New Class of Potent Cdc7 Inhibitors Designed by Putative Pharmacophore Model: Synthesis and Biological Evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1h)-ones
- 5u7q: Identification of a New Class of Potent Cdc7 Inhibitors Designed by Putative Pharmacophore Model: Synthesis and Biological Evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1h)-ones
- 5tzm: 59th Ig Domain of Human Obscurin (obscn Ig59)
- 5tx5: Rip1 Kinase ( Flag 1-294, C34A, C127A, C233A, C240A) with Gsk772
- 5tx3: Structure of Maternal Embryonic Leucine Zipper Kinase
- 5twz: Structure of Maternal Embryonic Leucine Zipper Kinase
- 5twy: Structure of Maternal Embryonic Leucine Zipper Kinase
- 5twu: Structure of Maternal Embryonic Leucine Zipper Kinase
- 5twl: Structure of Maternal Embryonic Leucine Zipper Kinase
- 5tvt: Structure of Maternal Embryonic Leucine Zipper Kinase
- 5tur: Pim-1 Kinase in Complex with a 7-azaindole
- 5tos: Botrytis-induced Kinase 1 (bik1) from Arabidopsis Thaliana
- 5toe: Pim-1 Kinase in Complex with a 7-azaindole
- 5tf9: Crystal Structure of Wnk1 in Complex with Mn2+amppnp and Wnk476
- 5tex: Pim-1 Kinase in Complex with a 7-azaindole
- 5tel: Pim-1 Kinase in Complex with a 7-azaindole
- 5te0: Crystal Structure of Adaptor Protein 2 Associated Kinase (aak1) in Complex with Bibf 1120
- 5t5t: Ampk Bound to Allosteric Activator
- 5t31: Exploiting an Asp-glu Switch in Glycogen Synthase Kinase 3 to Design Paralog Selective Inhibitors for Use in Acute Myeloid Leukemia
- 5t23: PI3KG in Complex with 5d
- 5t1t: Irak4 Kinase - Compound 1 Co-structure
- 5t1s: Irak4 Kinase - Compound 1 Co-structure
- 5t1h: Crystal Structure of Ck2
- 5sxk: Crystal Structure of PI3KALPHA in Complex with Fragment 18
- 5sxj: Crystal Structure of PI3KALPHA in Complex with Fragment 29
- 5sxi: Crystal Structure of PI3KALPHA in Complex with Fragment 13
- 5sxf: Crystal Structure of PI3KALPHA in Complex with Fragment 9
- 5sxe: Crystal Structure of PI3KALPHA in Complex with Fragments 19 and 28
- 5sxd: Crystal Structure of PI3KALPHA in Complex with Fragment 22
- 5sxc: Crystal Structure of PI3KALPHA in Complex with Fragment 8
- 5sxb: Crystal Structure of PI3KALPHA in Complex with Fragment 23
- 5sxa: Crystal Structure of PI3KALPHA in Complex with Fragment 10
- 5sx9: Crystal Structure of PI3KALPHA in Complex with Fragment 14
- 5sx8: Crystal Structure of PI3KALPHA in Complex with Fragments 12 and 15
- 5swt: Crystal Structure of PI3KALPHA in Complex with Fragments 17 and 27
- 5swr: Crystal Structure of PI3KALPHA in Complex with Fragments 20 and 26
- 5swp: Crystal Structure of PI3KALPHA in Complex with Fragments 6 and 24
- 5swo: Crystal Structure of PI3KALPHA in Complex with Fragments 4 and 19
- 5swg: Crystal Structure of PI3KALPHA in Complex with Fragments 5 and 21
- 5sw8: Crystal Structure of PI3KALPHA in Complex with Fragments 7 and 11
- 5sv7: The Crystal Structure of a Chaperone
- 5oyf: The Crystal Structure of CK2ALPHA in Complex with Compound 31
- 5oy4: GSK3BETA Complex with N-(6-(3,4-dihydroxyphenyl)-1h-pyrazolo[3,4- B]pyridin-3-yl)acetamide
- 5owr: Human Stk10 Bound to Dasatinib
- 5owq: Human Stk10 Bound to Dovitinib
- 5owl: Low Salt Structure of Human Protein Kinase CK2ALPHA in Complex with 3- Aminopropyl-4,5,6,7-tetrabromobenzimidazol
- 5owh: High Salt Structure of Human Protein Kinase CK2ALPHA in Complex with 3-aminopropyl-4,5,6,7-tetrabromobenzimidazol
- 5ouu: The Crystal Structure of CK2ALPHA in Complex with Compound 22
- 5oum: The Crystal Structure of CK2ALPHA in Complex with Compound 21
- 5oul: The Crystal Structure of CK2ALPHA in Complex with Compound 9
- 5oue: The Crystal Structure of CK2ALPHA in Complex with Compound 20
- 5otz: The Crystal Structure of CK2ALPHA in Complex with Compound 1
- 5oty: The Crystal Structure of CK2ALPHA in Complex with Cam4712
- 5ots: The Crystal Structure of CK2ALPHA in Complex with an Analogue of Compound 22
- 5otr: The Crystal Structure of CK2ALPHA in Complex with Compound 14
- 5otq: The Crystal Structure of CK2ALPHA in Complex with Compound 33
- 5otp: The Crystal Structure of CK2ALPHA in Complex with an Analogue of Compound 22
- 5oto: The Crystal Structure of CK2ALPHA in Complex with Compound 30
- 5otl: The Crystal Structure of CK2ALPHA in Complex with Compound 29
- 5oti: The Crystal Structure of CK2ALPHA in Complex with Compound 27
- 5oth: The Crystal Structure of CK2ALPHA in Complex with Compound 26
- 5otf: Mrck Beta in Complex with Bdp-00009066
- 5ote: Mrck Beta in Complex with Bdp-00008900
- 5otd: The Crystal Structure of CK2ALPHA in Complex with Compound 25
- 5ot6: The Crystal Structure of CK2ALPHA in Complex with Compound 19
- 5ot5: The Crystal Structure of CK2ALPHA in Complex with Compound 24
- 5osz: The Crystal Structure of CK2ALPHA in Complex with Compound 23
- 5osu: The Crystal Structure of CK2ALPHA in Complex with Analogues of Compound 1
- 5osr: The Crystal Structure of CK2ALPHA in Complex with an Analogue of Compound 1
- 5osp: The Crystal Structure of CK2ALPHA in Complex with an Analogue of Compound 1
- 5osl: The Crystal Structure of CK2ALPHA in Complex with Compound 7
- 5osf: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5ose: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5osd: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5os8: The Crystal Structure of CK2ALPHA in Complex with Compound 11
- 5os7: The Crystal Structure of CK2ALPHA in Complex with Compound 4
- 5os6: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5os5: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5os4: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5os3: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5os2: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5os1: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5os0: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5orz: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5ory: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5orx: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5orw: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5orv: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5ort: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5ors: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5orr: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5orp: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5oro: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5orn: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5orl: Crystal Structure of Aurora-a Kinase in Complex with an Allosterically Binding Fragment
- 5ork: The Crystal Structure of CK2ALPHA in Complex with Compound 6
- 5orj: The Crystal Structure of CK2ALPHA in Complex with Compound 3
- 5orh: The Crystal Structure of CK2ALPHA in Complex with Compound 2
- 5oqu: The Crystal Structure of CK2ALPHA in Complex with Compound 5
- 5oq8: Structure of Chk1 12-pt. Mutant Complex with Arylbenzamide Lrrk2 Inhibitor
- 5oq7: Structure of Chk1 8-pt. Mutant Complex with Arylbenzamide Lrrk2 Inhibitor
- 5oq6: Structure of Chk1 12-pt. Mutant Complex with Aminopyrimido- Benzodiazepinone Lrrk2 Inhibitor
- 5oq5: Structure of Chk1 8-pt. Mutant Complex with Aminopyrimido- Benzodiazepinone Lrrk2 Inhibitor
- 5oq4: Pqr309 - a Potent, Brain-penetrant, Orally Bioavailable, Pan-class I PI3K/MTOR Inhibitor as Clinical Candidate in Oncology
- 5opv: Structure of Chk1 10-pt. Mutant Complex with Pyrrolopyridine Lrrk2 Inhibitor
- 5opu: Structure of Chk1 10-pt. Mutant Complex with Pyrrolopyridine Lrrk2 Inhibitor
- 5ops: Structure of Chk1 10-pt. Mutant Complex with Pyrrolopyridine Lrrk2 Inhibitor
- 5opr: Structure of Chk1 10-pt. Mutant Complex with Aminopyridine Lrrk2 Inhibitor
- 5opb: Structure of Chk1 10-pt. Mutant Complex with Indazole Lrrk2 Inhibitor
- 5op7: Structure of Chk1 10-pt. Mutant Complex with Pyrrolopyrimidine Lrrk2 Inhibitor
- 5op5: Structure of Chk1 10-pt. Mutant Complex with Pyrrolopyrimidine Lrrk2 Inhibitor
- 5op4: Structure of Chk1 10-pt. Mutant Complex with Aminopyrimidine Lrrk2 Inhibitor
- 5op2: Structure of Chk1 10-pt. Mutant Complex with Arylbenzamide Lrrk2 Inhibitor
- 5oot: Structure of Chk1 10-pt. Mutant Complex with Aminopyrimido- Benzodiazepinone Lrrk2 Inhibitor
- 5oor: Structure of Chk1 10-pt. Mutant Complex with Staurosporine
- 5oop: Structure of Chk1 10-pt. Mutant Complex with Amp-pnp
- 5ooi: Structure of Protein Kinase Ck2 Catalytic Subunit (isoform CK2ALPHA') in Complex with The Indenoindole-type Inhibitor 4p
- 5oni: Low-salt Structure of Protein Kinase Ck2 Catalytic Subunit (isoform CK2ALPHA) in Complex with The Indenoindole-type Inhibitor 4p
- 5one: Crystal Structure of Aurora-a in Complex with Fmf-03-145-1 (compound 2)
- 5omy: High-salt Structure of Protein Kinase Ck2 Catalytic Subunit (isoform CK2ALPHA) in Complex with The Indenoindole-type Inhibitor 4p
- 5okt: Crystal Structure of Human Casein Kinase I Delta in Complex with Iwp-2
- 5odt: Aurora-a in Complex with Tacc3
- 5oc7: Crystal Structure of The Pleckstrin-homology Domain of Bcr-abl in Complex with Monobody Mb(bcr-ph_4).
- 5obr: Aurora a Kinase in Complex with 2-(3-chloro-5-fluorophenyl)quinoline- 4-carboxylic Acid and Jnj-7706621
- 5obj: Aurora a Kinase in Complex with 2-(3-fluorophenyl)quinoline-4- Carboxylic Acid and Atp
- 5o33: A Structure of The Gef Kalirin Dh1 Domain in Complex with The Small Gtpase Rac1
- 5o2c: Crystal Structure of Wnk3 Kinase and Cct1 Didomain in a Unphosphorylated State
- 5o2b: Crystal Structure of Wnk3 Kinase Domain in a Diphosphorylated State and in a Complex with The Inhibitor Pp-121
- 5o26: Crystal Structure of Wnk3 Kinase Domain in a Diphosphorylated State and in Complex with Amp-pnp/mg2+
- 5o23: Crystal Structure of Wnk3 Kinase Domain in a Monophosphorylated Apo State
- 5o21: Crystal Structure of Wnk3 Kinase Domain in a Monophosphorylated State with Chloride Bound in The Active Site
- 5o1v: Crystal Structure of Wnk3 Kinase Domain in a Monophosphorylated Apo State (a-loop Swapped)
- 5o1s: Dimethyl Fumarate Is an Allosteric Covalent Inhibitor of The P90 Ribosomal S6 Kinases
- 5o13: Crystal Structure of Pim1 Kinase in Complex with Small-molecule Inhibitor
- 5o12: Crystal Structure of Pim1 Kinase in Complex with Small-molecule Inhibitor
- 5o11: Crystal Structure of Pim1 Kinase in Complex with Small-molecule Inhibitor
- 5o0y: Tlk2 Kinase Domain from Human
- 5nyy: Formylglycine Generating Enzyme from T. Curvata in Complex with Cd(ii)
- 5nxl: Formylglycine Generating Enzyme from T. Curvata in Complex with Ag(i)
- 5nxd: Lim Domain Kinase 2 (limk2) in Complex with Th-300
- 5nxc: Lim Domain Kinase 1 (limk1) in Complex with Pf-00477736
- 5nqc: CK2ALPHA in Complex with Nmr154
- 5np1: Open Protomer of Human Atm (ataxia Telangiectasia Mutated)
- 5np0: Closed Dimer of Human Atm (ataxia Telangiectasia Mutated)
- 5nod: Pasta Subunit 4 of Streptococcus Pneumoniae Stkp Crystallized with Peg and Succinate
- 5nkp: Crystal Structure of The Human Klhl3 Kelch Domain in Complex with a Wnk3 Peptide
- 5ng3: Structure of Inactive Kinase RIP2K(K47R)
- 5ng2: Structure of RIP2K(D146N) with Bound Staurosporine
- 5ng0: Structure of RIP2K(L294F) with Bound Amppcp
- 5ndt: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensus Peptide and Fragment like Molecule (e)-3-(2-(thiophen-2-yl)vinyl)-3, 4-dihydroquinoxalin-2(1h)-one
- 5ncn: Crystal Structure Dbf2(ntr)-mob1 Complex
- 5ncm: Crystal Structure Cbk1(ntr)-mob2 Complex
- 5ncl: Crystal Structure of The Cbk1-mob2 Kinase-coactivator Complex with an Ssd1 Peptide
- 5n9n: Crystal Structure of Human Protein Kinase Ck2 Catalytic Subunit in Complex with The Atp-competitive, Tight-binding Dibenzofuran Inhibitor Tf85 (4a)
- 5n9l: Crystal Structure of Human Protein Kinase Ck2 Catalytic Subunit in Complex with The Atp-competitive Dibenzofuran Inhibitor Tf (4b)
- 5n9k: Crystal Structure of Human Protein Kinase Ck2 Catalytic Subunit in Complex with The Atp-competitive, Tight-binding Dibenzofuran Inhibitor Tf107 (5)
- 5n8y: Kaicba Circadian Clock Backbone Model Based on a Cryo-em Density
- 5n7g: Magi-1 Complexed with a Synthetic Prsk1 Peptide
- 5n7f: Magi-1 Complexed with a Prsk1 Peptide
- 5n7e: Crystal Structure of The Dbl-homology Domain of Bcr-abl in Complex with Monobody Mb(bcr-dh_4).
- 5n7d: Magi-1 Complexed with a Rsk1 Peptide
- 5n6r: Solution Structure of The Dbl-homology Domain of Bcr-abl
- 5n5m: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensuspeptide and (r)-3-(2-((isoquinolin-5-ylmethyl)(methyl) Carbamoyl)phenyl)pyrrolidin-1-ium
- 5n5l: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensuspeptide and [2-oxo-2-(1h-pyrrol-2-yl)ethyl] 5-bromo-1h- Indole-3-carboxylate
- 5n52: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensus Peptide and Fragment like Molecule (e)-3-(2,3-dimethoxyphenyl)acrylic Acid
- 5n51: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensus Peptide and Fragment like Molecule 3,4-dibromothiophene-2-carboxylic Acid
- 5n50: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensus Peptide and Fragment like Molecule 2-(4-chlorophenyl) Sulfanylacetohydrazide
- 5n4z: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensus Peptide and Fragment like Molecule (e)-4-(4-hydroxyphenyl)but-3-en-2- One
- 5n4y: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensus Peptide and Fragment like Molecule 2,5-dihydro-1h-isothiochromeno[3, 4-d]pyrazol-3-one
- 5n4x: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensuspeptide and Fragment like Molekule 4,5-dibromothiophene-2- Carbohydrazide
- 5n4v: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensuspeptide and Fragment like Molekule 2-cyclopropyl-4,5- Dimethylthieno[5,4-d]pyrimidine-6-carboxylic Acid
- 5n4u: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensuspeptide and Fragment like Molekule 5-(2-amino-1,3-thiazol-4- Yl)-1,3-dihydrobenzimidazol-2-one
- 5n4r: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensus Peptide and Fragment like Molecule 2-(azepan-1-yl)-1-(1h-indol-3-yl) Propan-1-one
- 5n4o: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensuspeptide and Fragment like Molekule (e)-3-(p-tolyl)acrylic Acid
- 5n4n: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensus Peptide and Fragment like Molecule 3,4-dimethyl-5-(1h-1,2,4-triazol- 3-yl)thiophene-2-carbonitrile
- 5n1v: Crystal Structure of The Protein Kinase Ck2 Catalytic Subunit in Complex with Pyrazolo-pyrimidine Macrocyclic Ligand
- 5mzl: Crystal Structure of Human Pim-1 Kinase in Complex with a Consensuspeptide and Fragment like Molekule N-quinolin-5-ylpyridine- 3-carboxamide
- 5myv: Crystal Structure of Srpk2 in Complex with Compound 1
- 5myc: Crystal Structure of Human 14-3-3 Sigma in Complex with Lrrk2 Peptide Ps910
- 5my9: Crystal Structure of Human 14-3-3 Sigma in Complex with Lrrk2 Peptide Ps935
- 5my8: Crystal Structure of Srpk1 in Complex with Sphinx31
- 5mrd: Human Pdk1-pkciota Kinase Chimera in Complex with Allosteric Compound Ps267 Bound to The Pif-pocket
- 5mqv: Crystal Structure of Human Casein Kinase I Delta in Complex with 4-(2, 5-dimethoxyphenyl)-n-(4-(5-(4-fluorphenyl)-2-(methylthio)-1h- Imidazol-4-yl)-pyridin-2-yl)-1-methyl-1h-pyrrole-2-carboxamide
- 5mpj: 1-(2-chloro-[1,1'-biphenyl]-4-yl)-n-methylethanamine
- 5mp8: Crystal Structure of CK2ALPHA with Zt0432 Bound
- 5mow: Crystal Structure of CK2ALPHA with Zt0432 Bound
- 5mov: Crystal Structure of CK2ALPHA with Zt0633 Bound
- 5mot: Crystal Structure of CK2ALPHA with Zt0627 Bound
- 5moh: Crystal Structure of CK2ALPHA with Zt0583 Bound.
- 5moe: Crystal Structure of CK2ALPHA with N-(3-(((2-chloro-[1,1'-biphenyl]-4- Yl)methyl)amino)propyl)methanesulfonamide Bound
- 5mod: Crystal Structure of CK2ALPHA with N-(3-(((2-chloro-[1,1'-biphenyl]-4- Yl)methyl)amino)propyl)methanesulfonamide Bound
- 5mo8: Crystal Structure of CK2ALPHA with N-(3-(((2-chloro-[1,1'-biphenyl]-4- Yl)methyl)amino)propyl)methanesulfonamide Bound
- 5mo7: Crystal Structure of CK2ALPHA with N-(3-(((2-chloro-[1,1'-biphenyl]-4- Yl)methyl)amino)propyl)methanesulfonamide Bound
- 5mo6: Crystal Structure of CK2ALPHA with N-(3-(((2-chloro-[1,1'-biphenyl]-4- Yl)methyl)amino)propyl)methanesulfonamide Bound
- 5mo5: Crystal Structure of CK2ALPHA with N-(3-(((2-chloro-[1,1'-biphenyl]-4- Yl)methyl)amino)propyl)methanesulfonamide Bound
- 5mmr: Crystal Structure of CK2ALPHA with N-((2-chloro-[1,1'-biphenyl]-4-yl) Methyl)butane-1,4-diamine Bound
- 5mmf: Crystal Structure of CK2ALPHA with Compound 7 Bound
- 5mg2: Crystal Structure of The Second Bromodomain of Human Taf1 in Complex with Bay-299 Chemical Probe
- 5mai: Crystal Structure of Melk in Complex with an Inhibitor
- 5mah: Crystal Structure of Melk in Complex with an Inhibitor
- 5mag: Crystal Structure of Melk in Complex with an Inhibitor
- 5maf: Crystal Structure of Melk in Complex with an Inhibitor
- 5m5a: Crystal Structure of Melk in Complex with an Inhibitor
- 5m57: Nek2 Bound to Arylaminopurine 6
- 5m56: Monoclinic Complex Structure of Human Protein Kinase Ck2 Catalytic Subunit (isoform CK2ALPHA') with The Inhibitor 4'-carboxy-6,8-chloro- Flavonol (flc21)
- 5m55: Nek2 Bound to Arylaminopurine 71
- 5m53: Nek2 Bound to Arylaminopurine Inhibitor 11
- 5m51: Nek2 Bound to Arylaminopurine Compound 8
- 5m4u: Orthorhombic Complex Structure of Human Protein Kinase Ck2 Catalytic Subunit (isoform CK2ALPHA') with The Inhibitor 4'-carboxy-6,8-chloro- Flavonol (flc21)
- 5m4i: Complex Structure of Human Protein Kinase Ck2 Catalytic Subunit with The Inhibitor 4'-carboxy-6,8-chloro-flavonol (flc21) Crystallized under High-salt Conditions
- 5m4f: Complex Structure of Human Protein Kinase Ck2 Catalytic Subunit with The Inhibitor 4'-carboxy-6,8-chloro-flavonol (flc21) Crystallized under Low-salt Conditions
- 5m4c: Complex Structure of Human Protein Kinase Ck2 Catalytic Subunit with a Thieno[2,3-d]pyrimidin Inhibitor Crystallized under Low-salt Conditions
- 5m44: Complex Structure of Human Protein Kinase Ck2 Catalytic Subunit with a Thieno[2,3-d]pyrimidin Inhibitor Crystallized under High-salt Conditions
- 5m09: Crystal Structure of Mycobacterium Tuberculosis Pkni Kinase Domain, C20A_R136N Double Mutant
- 5m08: Crystal Structure of Mycobacterium Tuberculosis Pkni Kinase Domain, C20A_R136A Double Mutant
- 5m07: Crystal Structure of Mycobacterium Tuberculosis Pkni Kinase Domain, C20A Mutant
- 5m06: Crystal Structure of Mycobacterium Tuberculosis Pkni Kinase Domain
- 5lxm: Crystal Structure of Aurora-a Bound to a Hydrocarbon-stapled Proteomimetic of Tpx2
- 5lvp: Human Pdk1 Kinase Domain in Complex with an Hm-peptide Bound to The Pif-pocket
- 5lvo: Human Pdk1 Kinase Domain in Complex with Allosteric Compound Pse10 Bound to The Pif-pocket
- 5lvn: Human Pdk1 Kinase Domain in Complex with Adenosine Bound to The Atp- Binding Site
- 5lvm: Human Pdk1 Kinase Domain in Complex with Adenine Bound to The Atp- Binding Site
- 5lvl: Human Pdk1 Kinase Domain in Complex with Compound Ps653 Bound to The Atp-binding Site
- 5luq: Crystal Structure of Human Dna-dependent Protein Kinase Catalytic Subunit (dna-pkcs)
- 5lpz: Crystal Structure of The Bri1 Kinase Domain (865-1196) in Complex with Adp from Arabidopsis Thaliana
- 5lpy: Crystal Structure of The Bri1 Kinase Domain (865-1160) in Complex with Atp from Arabidopsis Thaliana
- 5lpw: Crystal Structure of The Apo-bri1 Kinase Domain (865-1160)
- 5lpv: Crystal Structure of The Bri1 Kinase Domain (865-1160) in Complex with Amppnp and Mn from Arabidopsis Thaliana
- 5lpb: Crystal Structure of The Bri1 Kinase Domain (865-1160) in Complex with Adp from Arabidopsis Thaliana
- 5loh: Kinase Domain of Human Greatwall
- 5lcw: Cryo-em Structure of The Anaphase-promoting Complex/cyclosome, in Complex with The Mitotic Checkpoint Complex (apc/c-mcc) at 4.2 Angstrom Resolution
- 5l9u: Model of Human Anaphase-promoting Complex/cyclosome (apc/c-cdh1) with a cross Linked Ubiquitin VARIANT-SUBSTRATE-UBE2C (ubch10) Complex Representing Key Features of Multiubiquitination
- 5l9t: Model of Human Anaphase-promoting Complex/cyclosome (apc/c-cdh1) with E2 UBE2S Poised for Polyubiquitination Where UBE2S, Apc2, and Apc11 Are Modeled into Low Resolution Density
- 5l8l: Aurora-a Kinase Domain in Complex with Vnar-d01 (crystal Form 1)
- 5l8k: Aurora-a Kinase Domain in Complex with Vnar-d01 (crystal Form 2)
- 5l8j: Aurora-a Kinase Domain in Complex with Vnar-d01 S93R
- 5l6w: Structure of The Limk1-atpgammas-cfl1 Complex
- 5l4q: Crystal Structure of Adaptor Protein 2 Associated Kinase 1 (aak1) in Complex with Lkb1 (aak1 Dual Inhibitor)
- 5l2q: Serine/threonine-protein Kinase 40 (stk40) Kinase Homology Domain
- 5kzi: Crystal Structure of Human Pim-1 Kinase in Complex with an Imidazopyridazine Inhibitor.
- 5kz8: Mark2 Complex with 7-[(1s)-1-(4-fluorophenyl)ethyl]-5,5-dimethyl-2-(3- Pyridylamino)pyrrolo[2,3-d]pyrimidin-6-one
- 5kz7: Mark2 Complex with 7-[(1s)-1-(4-fluorophenyl)ethyl]-5,5-dimethyl-2-(3- Pyridylamino)pyrrolo[2,3-d]pyrimidin-6-one
- 5kx8: Irak4-inhibitor Co-structure
- 5kx7: Irak4-inhibitor Co-structure
- 5kwh: Crystal Structure of Ck2
- 5ku8: Crystal Structure of Ck2
- 5kq5: Ampk Bound to Allosteric Activator
- 5kpm: Glycogen Synthase Kinase 3 Beta Complexed with Brd3731
- 5kpl: Glycogen Synthase Kinase 3 Beta Complexed with Brd0705
- 5kpk: Glycogen Synthase Kinase 3 Beta Complexed with Brd0209
- 5kkt: Rock 1 Bound to Azaindole Thiazole Piperazine Inhibitor
- 5kks: Rock 1 Bound to Azaindole Thiazole Inhibitor
- 5kkr: Ksr2:mek1 Complex Bound to The Small Molecule Aps-2-79
- 5khu: Model of Human Anaphase-promoting Complex/cyclosome (apc15 Deletion Mutant), in Complex with The Mitotic Checkpoint Complex (apc/c-cdc20- Mcc) Based on Cryo Em Data at 4.8 Angstrom Resolution
- 5kgk: Crystal Structure of Pim1 with Inhibitor: 3-(4-methoxyphenyl)-1~{h}- Pyrazol-5-amine
- 5kgi: Crystal Structure of Pim1 with Inhibitor 2-[3,4-bis(chloranyl) Phenoxy]ethanamine
- 5kgg: Crystal Structure of Pim1 with Inhibitor: 2-(5-chloranyl-1~{h}-indol- 3-yl)ethanamine
- 5kge: Crystal Structure of Pim1 with Inhibitor: 5-(3,4-dichlorophenyl)- 1~{h}-pyrazol-3-amine
- 5kgd: Crystal Structure of Pim1 with Inhibitor: 2-pyridin-3-yl-1~{h}- Benzimidazole
- 5kcx: Pim-1 Kinase in Complex with a Selective N-substituted 7-azaindole Inhibitor
- 5kcv: Crystal Structure of Allosteric Inhibitor, Arq 092, in Complex with Autoinhibited Form of Akt1
- 5kc2: Negative Stain Structure of Vps15/vps34 Complex
- 5kbr: Pak1 in Complex with 7-azaindole Inhibitor
- 5kbq: Pak1 in Complex with Bis-anilino Pyrimidine Inhibitor
- 5kae: Crystal Structure of Human PI3K-GAMMA in Complex with Quinoline- Containing Inhibitor 5g
- 5k98: Structure of Hipa-hipb-o2-o3 Complex
- 5k7i: Irak4 in Complex with Az3864
- 5k7g: Irak4 in Complex with Az3862
- 5k76: Irak4 in Complex with Compound 28
- 5k75: Irak4 in Complex with Compound 1
- 5k72: Irak4 in Complex with Compound 21
- 5k5n: Crystal Structure of Gsk-3beta Complexed with Pf-04802367, a Highly Selective Brain-penetrant Kinase Inhibitor
- 5k3y: Crystal Structure of Aurorab/incenp in Complex with Bi 811283
- 5k00: Melk in Complex with Nvs-melk5
- 5jzn: Crystal Structure of Dclk1-kd in Complex with Nvp-tae684
- 5jzj: Crystal Structure of Dclk1-kd in Complex with Amppn
- 5jwr: Crystal Structure of Foldswitch-stabilized Kaib in Complex with The N- Terminal Ci Domain of Kaic and a Dimer of Kaia C-terminal Domains from Thermosynechococcus Elongatus
- 5jwq: Crystal Structure of Kaic S431E in Complex with Foldswitch-stabilized Kaib from Thermosynechococcus Elongatus
- 5jwo: Crystal Structure of Foldswitch-stabilized Kaib in Complex with The N- Terminal Ci Domain of Kaic from Thermosynechococcus Elongatus
- 5jt2: BRAFV600E Kinase Domain in Complex with Chemically Linked Vemurafenib Inhibitor Vem-bisamide
- 5jsm: BRAFV600E Kinase Domain in Complex with Chemically Linked Vemurafenib Inhibitor Vem-3-vem
- 5jrq: BRAFV600E Kinase Domain in Complex with Chemically Linked Vemurafenib Inhibitor Vem-6-vem
- 5joe: Crystal Structure of I81 from Titin
- 5jmv: Crystal Structure of Mjkae1-pfupcc1 Complex
- 5jk7: The X-ray Structure of The Ddb1-dcaf1-vpr-ung2 Complex
- 5jja: Crystal Structure of a PP2A B56GAMMA/BUBR1 Complex
- 5jhb: Structure of Phosphoinositide 3-kinase Gamma (PI3K) Bound to The Potent Inhibitor Pikin3
- 5jha: Structure of Phosphoinositide 3-kinase Gamma (PI3K) Bound to The Potent Inhibitor Pikin2
- 5jfk: Crystal Structure of a Tdr Receptor
- 5jfi: Crystal Structure of a Tdif-tdr Complex
- 5jdj: Crystal Structure of Domain I10 from Titin in Space Group P212121
- 5jde: Crystal Structure of I9-i11 Tandem from Titin (p1)
- 5jdd: Crystal Structure of I9-i11 Tandem from Titin (p212121)
- 5jda: Bacillus Cereus Coth Kinase plus Mg2+/amp
- 5j95: MAP4K4 in Complex with Inhibitor
- 5j7b: The Identification and Pharmacological Characterization of 6-(tert- Butylsulfonyl)-n-(5-fluoro-1h-indazol-3-yl)quinolin-4-amine (gsk583), a Highly Potent and Selective Inhibitor of Rip2 Kinase, Gsk583 Complex
- 5j79: The Identification and Pharmacological Characterization of 6-(tert- Butylsulfonyl)-n-(5-fluoro-1h-indazol-3-yl)quinolin-4-amine (gsk583), a Highly Potent and Selective Inhibitor of Rip2 Kinase, Compound 3 Complex
- 5j5t: Glk Co-crystal Structure with Aminopyrrolopyrimidine Inhibitor
- 5j2r: Solution Structure of Ras Binding Domain (rbd) of B-raf
- 5j18: Solution Structure of Ras Binding Domain (rbd) of B-raf Complexed with Rigosertib (complex I)
- 5j17: Solution Structure of Ras Binding Domain (rbd) of B-raf
- 5iyx: Crystal Structure of The Arabidopsis Receptor Kinase Haesa in Complex with The Peptide Hormone Ida and The Co-receptor Serk1
- 5iyv: Crystal Structure of The Arabidopsis Receptor Kinase Haesa Lrr Ectdomain in Complex with The Peptide Hormone Idl1.
- 5ixt: The Crystal Structure of The Arabidopsis Receptor Kinase Haesa Lrr Ectdomain in Complex with a N-terminal Extended Ida Peptide Hormone Ligand.
- 5ixq: Crystal Structure of The Arabidopsis Receptor Kinase Haesa Lrr Ectdomain in Complex with The Peptide Hormone Ida.
- 5ixo: Crystal Structure of The Arabidopsis Receptor Kinase Haesa Lrr Ectdomain (apo Form).
- 5itd: Crystal Structure of PI3K Alpha with PI3K Delta Inhibitor
- 5ita: Crystal Structure of Braf Kinase Domain Bound to Az-vem
- 5iso: Structure of Full Length Human Ampk (non-phosphorylated at T-loop) in Complex with a Small Molecule Activator, a Benzimidazole Derivative (991)
- 5ipj: Crystal Structure of Human Pim-1 Kinase in Complex with a Quinazolinone-pyrrolopyrrolone Inhibitor.
- 5ime: Crystal Structure of P21-activated Kinase 1 (pak1) in Complex with Compound 9
- 5ikw: Crystal Structure of Bmp-2-inducible Kinase in Complex with an Indazole Inhibitor
- 5iis: Design, Synthesis and Structure Activity Relationship of Potent Pan- Pim Kinase Inhibitors Derived from The Pyridyl-amide Scaffold
- 5ihc: Melk in Complex with NVS-MELK12B
- 5iha: Melk in Complex with NVS-MELK8F
- 5ih9: Melk in Complex with NVS-MELK8A
- 5ih8: Melk in Complex with Nvs-melk1
- 5ih6: Human Casein Kinase 1 Isoform Delta (kinase Domain) in Complex with Epiblastin a Derivative
- 5ih5: Human Casein Kinase 1 Isoform Delta (kinase Domain) in Complex with Epiblastin a
- 5ih4: Human Casein Kinase 1 Isoform Delta Apo (kinase Domain)
- 5i3r: Crystal Structure of Bmp-2-inducible Kinase in Complex with an Indazole Inhibitor
- 5i3o: Crystal Structure of Bmp-2-inducible Kinase in Complex with an Indazole Inhibitor
- 5i0b: Structure of Pak4
- 5hz3: Plant Peptide Hormone Receptor Rgfr1 in Complex with Rgfr5
- 5hz1: Plant Peptide Hormone Receptor Rgfr1 in Complex with Rgf3
- 5hz0: Plant Peptide Hormone Receptor Rgfr1 in Complex with Rgf2
- 5hyx: Plant Peptide Hormone Receptor Rgfr1 in Complex with Rgf1
- 5hx6: Crystal Structure of Rip1 Kinase with a Benzo[b][1,4]oxazepin-4-one
- 5hvu: Rho-associated Protein Kinase 1 (rock 1) in Complex with a Pyridine Thiazole Piperidine Inhibitor
- 5hvk: Crystal Structure of Limk1 Mutant D460N in Complex with Full-length Cofilin-1
- 5hvj: Crystal Structure of Limk1 D460N Mutant in Complex with Amp-pnp
- 5htc: Crystal Structure of Haspin (gsg2) in Complex with Bisubstrate Inhibitor Arc-3372
- 5htb: Crystal Structure of Haspin (gsg2) in Complex with Bisubstrate Inhibitor Arc-3353
- 5ho8: Discovery of Novel 7-azaindoles as Pdk1 Inhibitors
- 5ho7: Discovery of Novel 7-azaindoles as Pdk1 Inhibitors
- 5hng: Discovery of Novel 7-azaindoles as Pdk1 Inhibitors
- 5hlp: X-ray Crystal Structure of GSK3B in Complex with Brd3937
- 5hln: X-ray Crystal Structure of GSK3B in Complex with Chir99021
- 5hkm: Discovery of Novel 7-azaindoles as Pdk1 Inhibitors
- 5hie: Braf Kinase Domain B3AC Loop Deletion Mutant in Complex with Dabrafenib
- 5hid: Braf Kinase Domain B3AC Loop Deletion Mutant in Complex with Az628
- 5hi2: Braf Kinase Domain B3AC Loop Deletion Mutant in Complex with Sorafenib
- 5hgi: Crystal Structure of Apo Human Ire1 Alpha
- 5h8g: Crystal Structure of Ck2 with Compound 7b
- 5h8e: Crystal Structure of Ck2 with Compound 7h
- 5h8b: Crystal Structure of Ck2 with Compound 2
- 5h64: Cryo-em Structure of Mtorc1
- 5gr9: Crystal Structure of Pxy-tdif/cle41
- 5gr8: Crystal Structure of Pepr1-atpep1
- 5gqr: Crystal Structure of Pxy-cle41-serk2
- 5gpg: Co-crystal Structure of The Fk506 Binding Domain of Human Fkbp25, Rapamycin and The Frb Domain of Human Mtor
- 5gij: Crystal Structure of Tdr-tdif Complex
- 5g1x: Crystal Structure of Aurora-a Kinase in Complex with N-myc
- 5g15: Structure Aurora a (122-403) Bound to Activating Monobody Mb1 and Amppcp
- 5g04: Structure of The Human Apc-cdc20-hsl1 Complex
- 5fur: Structure of Human Tfiid-iia Bound to Core Promoter Dna
- 5flc: Architecture of Human Mtor Complex 1 - 5.9 Angstrom Reconstruction
- 5fi4: Discovery of Imidazo[1,2-a]-pyridine Inhibitors of Pan-pi3 Kinases That Are Efficacious in a Mouse Xenograft Model
- 5fd2: B-raf Wild-type Kinase Domain in Complex with a Purinylpyridinylamino- Based Inhibitor
- 5f95: Crystal Structure of GSK3B in Complex with Compound 18: 2- [(cyclopropylcarbonyl)amino]-n-(4-phenylpyridin-3-yl)pyridine-4- Carboxamide
- 5f94: Crystal Structure of GSK3B in Complex with Compound 15: 2- [(cyclopropylcarbonyl)amino]-n-(4-methoxypyridin-3-yl)pyridine-4- Carboxamide
- 5f5p: Molecular Basis for Shroom2 Recognition by Rock1
- 5f4n: Multi-parameter Lead Optimization to Give an Oral Chk1 Inhibitor Clinical Candidate: (r)-5-((4-((morpholin-2-ylmethyl)amino)-5- (trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (cct245737)
- 5ezv: X-ray Crystal Structure of Amp-activated Protein Kinase Alpha-2/alpha- 1 Rim Chimaera (alpha-2(1-347)/alpha-1(349-401)/alpha-2(397-end) Beta-1 Gamma-1) Co-crystallized with C2 (5-(5-hydroxyl-isoxazol-3- Yl)-furan-2-phosphonic Acid)
- 5eyk: Crystal Structure of Aurora B in Complex with Bi 847325
- 5ew9: Crystal Structure of Aurora a Kinase Domain Bound to Mk-5108
- 5es1: Crystal Structure of Microtubule Affinity-regulating Kinase 4 Catalytic Domain in Complex with a Pyrazolopyrimidine Inhibitor
- 5ep6: The Crystal Structure of Nap1 in Complex with Tbk1
- 5eol: Crystal Structure of Human Pim-1 Kinase in Complex with a Macrocyclic Quinoxaline-pyrrolodihydropiperidinone Inhibitor
- 5eof: Crystal Structure of Optn Ntd and Tbk1 Ctd Complex
- 5eoa: Crystal Structure of Optn E50K Mutant and Tbk1 Complex
- 5eds: Crystal Structure of Human PI3K-GAMMA in Complex with Benzimidazole Inhibitor 5
- 5eak: Optimization of Microtubule Affinity Regulating Kinase (mark) Inhibitors with Improved Physical Properties
- 5e12: Crystal Structure of Pasta Domains 2, 3 and 4 of Mycobacterium Tuberculosis Protein Kinase B
- 5e10: Crystal Structure of Pasta Domains 1 and 2 of Mycobacterium Tuberculosis Protein Kinase B
- 5e0z: Crystal Structure of Pasta Domains 3 and 4 of Mycobacterium Tuberculosis Protein Kinase B
- 5e0y: Crystal Structure of Pasta Domain 4 of Mycobacterium Tuberculosis Protein Kinase B
- 5dxt: P110ALPHA with Gdc-0326
- 5dxh: P110ALPHA/P85ALPHA with Compound 5
- 5dwr: Identification of N-(4-((1r,3s,5s)-3-amino-5-methylcyclohexyl)pyridin- 3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (pim447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (pim) 1,2 and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies
- 5dt4: Aurora a Kinase in Complex with Aa35 and Atp in Space Group P6122
- 5dt3: Aurora a Kinase in Complex with Atp in Space Group P6122
- 5dt0: Aurora a Kinase in Complex with Jnj-7706621 in Space Group P6122
- 5drd: Aurora a Kinase in Complex with Atp in Space Group P6122
- 5drb: Crystal Structure of Wnk1 in Complex with Wnk463
- 5dr9: Aurora a Kinase in Complex with Aa29 and Jnj-7706621 in Space Group P6122
- 5dr6: Aurora a Kinase in Complex with Aa30 and Jnj-7706621 in Space Group P6122
- 5dr2: Aurora a Kinase in Complex with Aa30 and Atp in Space Group P6122
- 5dpv: Aurora a Kinase in Complex with Aa35 and Jnj-7706621 in Space Group P6122
- 5dos: Aurora a Kinase in Complex with Aa35 and Atp in Space Group P6122
- 5dnr: Aurora a Kinase in Complex with Atp in Space Group P41212
- 5dn3: Aurora a in Complex with Atp and Aa35.
- 5dmz: Structure of Human Bub1 Kinase Domain Phosphorylated at Ser969
- 5dls: Identification of Novel, in Vivo Active Chk1 Inhibitors Utilizing Structure Guided Drug Design
- 5dia: Pim1 in Complex with Cpd36 ((1s,3s)-n1-(6-(5-(pyridin-3-yl)-1h- Pyrazolo[3,4-c]pyridin-3-yl)pyridin-2-yl)cyclohexane-1,3-diamine)
- 5di1: MAP4K4 in Complex with an Inhibitor
- 5dhj: Pim1 in Complex with Cpd4 (3-methyl-5-(pyridin-3-yl)-1h-pyrazolo[3,4- C]pyridine)
- 5dh3: Crystal Structure of Mst2 in Complex with Xmu-mp-1
- 5dgz: Discovery of 3,5-substituted 6-azaindazoles as Potent Pan-pim Inhibitors
- 5dfz: Structure of Vps34 Complex II from S. Cerevisiae.
- 5dfp: Crystal Structure of Pak1 in Complex with an Inhibitor Compound Frax1036
- 5dey: Crystal Structure of Pak1 in Complex with an Inhibitor Compound G-5555
- 5dew: Crystal Structure of Pak1 in Complex with an Inhibitor Compound 5
- 5de2: Structural Mechanism of Nek7 Activation by Nek9-induced Dimerisation
- 5dbx: Crystal Structure of Murine SPAK(T243D) in Complex with Amppnp
- 5d9l: Rsk2 N-terminal Kinase in Complex with Bis-phenol Pyrazole
- 5d9k: Rsk2 N-terminal Kinase in Complex with Bi-d1870
- 5d9h: Crystal Structure of Spak (stk39) Dimer in The Basal Activity State
- 5d7a: Crystal Structure of The Kinase Domain of Traf2 and Nck-interacting Protein Kinase with Ncb-0846
- 5czo: Structure of S. Cerevisiae Hrr25:mam1 Complex, Form 2
- 5cyz: Structure of S. Cerevisiae Hrr25:mam1 Complex, Form 1
- 5cx9: Crystal Structure of CK2ALPHA with (methyl 4-((3-(3-chloro-4-(phenyl) Benzylamino)propyl)amino)-4-oxobutanoate Bound
- 5cwz: Crystal Structure of The Kinase Domain of Human Traf2 and Nck- Interacting Protein Kinase
- 5cvh: Crystal Structure of CK2ALPHA
- 5cvg: Crystal Structure of CK2ALPHA with a Novel Closed Conformation of The ad Loop
- 5cvf: Crystal Structure of CK2ALPHA with Compound 5 Bound
- 5cu6: Crystal Structure of CK2ALPHA
- 5cu4: Crystal Structure of CK2ALPHA with Compound 10 Bound
- 5cu3: Crystal Structure of CK2ALPHA with Compound 10 Bound
- 5cu2: Crystal Structure of CK2ALPHA with 2-hydroxy-5-methylbenzoic Acid and (methyl 4-((3-(3-chloro-4-(phenyl)benzylamino)propyl)amino)-4- Oxobutanoat Bound
- 5cu0: Crystal Structure of CK2ALPHA with 2-hydroxy-5-methylbenzoic Acid and N-(3-(3-chloro-4-(phenyl)benzylamino)propyl)acetamide Bound
- 5ctp: Crystal Structure of CK2ALPHA with N-(3-(3-chloro-4-(phenyl) Benzylamino)propyl)acetamide Bound
- 5ct7: Braf in Complex with Raf265
- 5ct0: Crystal Structure of CK2ALPHA with 3-(3-chloro-4-(phenyl)benzylamino) Propan-1-ol Bound
- 5csx: Crystal Structure of B-raf in Complex with Bi 882370
- 5csw: B-raf in Complex with Dabrafenib
- 5csv: Crystal Structure of CK2ALPHA with Compound 6 Bound
- 5csp: Crystal Structure of CK2ALPHA with Compound 5 Bound
- 5csn: S100B-RSK1 Crystal Structure C
- 5csj: S100B-RSK1 Crystal Structure B
- 5csi: S100B-RSK1 Crystal Structure A'
- 5csh: Crystal Structure of CK2ALPHA with Compound 4 Bound
- 5csf: S100B-RSK1 Crystal Structure a
- 5cs6: Crystal Structure of CK2ALPHA with Compound 3 Bound
- 5cqw: Tetragonal Complex Structure of Protein Kinase Ck2 Catalytic Subunit with a Benzotriazole-based Inhibitor Generated by Click-chemistry
- 5cqu: Monoclinic Complex Structure of Protein Kinase Ck2 Catalytic Subunit with a Benzotriazole-based Inhibitor Generated by Click-chemistry
- 5clp: Crystal Structure of CK2ALPHA with 3,4-dichlorophenethylamine Bound
- 5ci7: Structure of Ulk1 Bound to a Selective Inhibitor
- 5c9c: Crystal Structure of BRAF(V600E) in Complex with Ly3009120 Compnd
- 5c1q: Serine/threonine-protein Kinase Pim-1
- 4red: Crystal Structure of Human Ampk Alpha1 Kd-aid with K43A Mutation
- 4rer: Crystal Structure of The Phosphorylated Human Alpha1 Beta2 Gamma1 Holo-ampk Complex Bound to Amp and Cyclodextrin
- 4rew: Crystal Structure of The Non-phosphorylated Human Alpha1 Beta2 Gamma1 Holo-ampk Complex
- 4rlk: Crystal Structure of Z. Mays CK2ALPHA in Complex with The Atp- Competitive Inhibitor 4-[(e)-(fluoren-9-ylidenehydrazinylidene)- Methyl] Benzoate
- 4rll: Crystal Structure of Human CK2ALPHA in Complex with The Atp- Competitive Inhibitor 4-[(e)-(fluoren-9-ylidenehydrazinylidene)- Methyl] Benzoate
- 4rqk: Crystal Structure of Pdk1 in Complex with Atp and The Pif-pocket Ligand Rs1
- 4rqv: Crystal Structure of Pdk1 in Complex with Atp and The Pif-pocket Ligand Rs2
- 4rrv: Crystal Structure of Pdk1 in Complex with Atp and Piftide
- 4uow: Crystal Structure of The Titin M10-obscurin Ig Domain 1 Complex
- 4wwn: Crystal Structure of Human PI3K-GAMMA in Complex with (s)-n-(1-(7- Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9h-purin-6-amine Amg319 Inhibitor
- 4wwo: Crystal Structure of Human PI3K-GAMMA in Complex with Phenylquinoline Inhibitor N-{(1s)-1-[8-chloro-2-(3-fluorophenyl)quinolin-3-yl]ethyl}- 9h-purin-6-amine
- 4wwp: Crystal Structure of Human PI3K-GAMMA in Complex with Pyridinylquinoline Inhibitor N-{(1s)-1-[8-chloro-2-(2-methylpyridin- 3-yl)quinolin-3-yl]ethyl}-9h-purin-6-amine
- 4o00: Crystal Structure of The Titin A-band Domain A3
- 6ntc: Crystal Structure of G12V Hras-gppnhp Bound in Complex with The Engineered Rbd Variant 1 of Craf Kinase Protein
- 3wow: Crystal Structure of Human CK2A with Amppnp
- 4mta: Crystal Structure of Pim-1 Kinase Domain in Complex with 2-methyl-5- Phenylfuran-3-carboxylic Acid
- 4ow8: Crystal Structure of Kinase Domain of Pkna from Mtb
- 5bs0: Mage-a3 Reactive Tcr in Complex with Titin Epitope in Hla-a1
- 5brm: Structural Basis for Mob1-dependent Activation of The Core Mst-lats Kinase Cascade in Hippo Signaling
- 5brk: Pmob1-lats1 Complex
- 5bms: Crystal Structure of P21-activated Kinase 4 in Complex with an Inhibitor Compound 29
- 5bml: Rock 1 Bound to a Pyridine Thiazole Inhibitor
- 5b6b: Complex of Lats1 and Phosphomimetic MOB1B
- 5b5w: Crystal Structure of Mob1-lats1 Ntr Domain Complex
- 5b0x: Crystal Structure of The CK2A/BENZOIC Acid Derivative Complex
- 5ax9: Crystal Structure of The Kinase Domain of Human Traf2 and Nck- Interacting Protein Kinase in Complex with Compund 9
- 5av4: Crystal Structure of Dapk1-genistein Complex in The Presence of Bromide Ions.
- 5av3: Crystal Structure of Dapk1-kaempferol Complex in The Presence of Iodide Ions.
- 5av2: Crystal Structure of Dapk1-kaempferol Complex in The Presence of Bromide Ions.
- 5av1: Crystal Structure of Dapk1 in The Presence of Bromide Ions.
- 5av0: Crystal Structure of Dapk1 in Complex with 7,3',4'- Trihydroxyisoflavone.
- 5auz: Crystal Structure of Dapk1 in Complex with Genistein.
- 5auy: Crystal Structure of Dapk1 in Complex with Morin.
- 5aux: Crystal Structure of Dapk1 in Complex with Kaempferol.
- 5auw: Crystal Structure of Dapk1 in Complex with Quercetin.
- 5auv: Crystal Structure of Dapk1 in Complex with Apigenin.
- 5auu: Crystal Structure of Dapk1 in Complex with Luteolin.
- 5aut: Crystal Structure of Dapk1 in Complex with Ans.
- 5ar8: Rip2 Kinase Catalytic Domain (1 - 310) Complex with Biphenylsulfonamide
- 5ar7: Rip2 Kinase Catalytic Domain (1 - 310) Complex with Biaryl Urea
- 5ar5: Rip2 Kinase Catalytic Domain (1 - 310) Complex with Benzimidazole
- 5ar4: Rip2 Kinase Catalytic Domain (1 - 310) Complex with Sb-203580
- 5ar3: Rip2 Kinase Catalytic Domain (1 - 310) Complex with Amp-pcp
- 5ar2: Rip2 Kinase Catalytic Domain (1 - 310)
- 5ack: Human Pdk1 Kinase Domain in Complex with Allosteric Compound 7 Bound to The Pif-pocket
- 4rlo: Human P70S6K1 with Ruthenium-based Inhibitor Em5
- 5aag: Aurora a Kinase Bound to an Imidazopyridine Inhibitor (14b)
- 5aaf: Aurora a Kinase Bound to an Imidazopyridine Inhibitor (14a)
- 5aae: Aurora a Kinase Bound to an Imidazopyridine Inhibitor (14d)
- 4rlp: Human P70S6K1 with Ruthenium-based Inhibitor Fl772
- 5aad: Aurora a Kinase Bound to an Imidazopyridine Inhibitor (7a)
- 4rpv: Co-crystal Structure of Pim1 with Compound 3
- 5a6o: Crystal Structure of The Apo Form of The Unphosphorylated Human Death Associated Protein Kinase 3 (dapk3)
- 5a6n: Crystal Structure of Human Death Associated Protein Kinase 3 (dapk3) in Complex with Compound 2
- 4ty1: Crystal Structure of Human Pim-1 Kinase in Complex with an Aminooxadiazole-indole Inhibitor.
- 4waf: Crystal Structure of a Novel Tetrahydropyrazolo[1,5-a]pyrazine in an Engineered PI3K Alpha
- 4wno: Structure of Ulk1 Bound to an Inhibitor
- 4wnp: Structure of Ulk1 Bound to a Potent Inhibitor
- 5a14: Human Cdk2 with Type II Inhibitor
- 4wrs: Crystal Structure of Human Pim-1 Kinase in Complex with an Azaspiro Pyrazinyl-indazole Inhibitor.
- 4wsy: Crystal Structure of Human Pim-1 Kinase in Complex with a Thiazolamine-indazole Inhibitor.
- 4wt6: Crystal Structure of Human Pim-1 Kinase in Complex with a Thiadiazolamine-indole Inhibitor.
- 4x3f: Crystal Structure of The Intracellular Domain of The M. Tuberculosis Ser/thr Kinase Pkna
- 4zy6: Crystal Structure of P21-activated Kinase 1 in Complex with an Inhibitor Compound 29
- 4zy5: Crystal Structure of P21-activated Kinase 1 in Complex with an Inhibitor Compound 17
- 4zy4: Crystal Structure of P21 Activated Kinase 1 in Complex with an Inhibitor Compound 4
- 4x7h: Co-crystal Structure of Perk Bound to N-{5-[(6,7-dimethoxyquinolin-4- Yl)oxy]pyridin-2-yl}-1-methyl-3-oxo-2-phenyl-5-(pyridin-4-yl)-2,3- Dihydro-1h-pyrazole-4-carboxamide Inhibitor
- 4x7j: Co-crystal Structure of Perk with 2-amino-n-[4-methoxy-3- (trifluoromethyl)phenyl]-4-methyl-3-[2-(methylamino)quinazolin-6- Yl]benzamide Inhibitor
- 4x7k: Co-crystal Structure of Perk Bound to 4-{2-amino-3-[5-fluoro-2- (methylamino)quinazolin-6-yl]-4-methylbenzoyl}-1-methyl-2,5-diphenyl- 1,2-dihydro-3h-pyrazol-3-one Inhibitor
- 4x7l: Co-crystal Structure of Perk Bound to 4-{2-amino-4-methyl-3-[2- (methylamino)-1,3-benzothiazol-6-yl]benzoyl}-1-methyl-2,5-diphenyl-1, 2-dihydro-3h-pyrazol-3-one Inhibitor
- 4x7n: Co-crystal Structure of Perk Bound to 4-[2-amino-4-methyl-3-(2- Methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenyl-1,2-dihydro-3h- Pyrazol-3-one Inhibitor
- 4x7o: Co-crystal Structure of Perk Bound to 1-[5-(4-amino-2,7-dimethyl-7h- Pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1h-indol-1-yl]-2-[3-fluoro- 5-(trifluoromethyl)phenyl]ethanone Inhibitor
- 4x7q: Pim2 Kinase in Complex with Compound 1s
- 4xhk: Pim1 Kinase in Complex with Compound 1s
- 4zts: Human Aurora a Catalytic Domain Bound to Fk1142
- 4ztr: Human Aurora a Catalytic Domain Bound to Fk1141
- 4ztq: Human Aurora a Catalytic Domain Bound to Fk932
- 4ztn: Irak4-inhibitor Co-structure
- 4ztm: Irak4-inhibitor Co-structure
- 4ztl: Irak4-inhibitor Co-structure
- 4zs0: Human Aurora a Catalytic Domain Bound to Sb-6-oh
- 4zp5: MAP4K4 in Complex with Inhibitor
- 4zop: Co-crystal Structure of Lipid Kinase PI3K Alpha with a Selective Phosphatidylinositol-3 Kinase Alpha Inhibitor
- 4zlo: Serine/threonine-protein Kinase Pak1 Complexed with a Dibenzodiazepine: Identification of an Allosteric Site on Pak1
- 4zk5: MAP4K4 in Complex with Inhibitor Gne-495
- 4zjj: Pak1 in Complex with (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro- Dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide
- 4zji: Pak1 in Complex with 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin- 1-yl)-dibenzodiazepine
- 4zhx: Novel Binding Site for Allosteric Activation of Ampk
- 5aik: Human DYRK1A in Complex with Ldn-211898
- 4z8l: Crystal Structure of Dcaf1/siv-mnd Vpx/mnd Samhd1 Ntd Ternary Complex
- 4z64: The Plant Peptide Hormone Receptor Complex in Arabidopsis
- 4z63: The Plant Peptide Hormone Receptor in Arabidopsis
- 4z62: The Plant Peptide Hormone Free Receptor
- 4z61: The Plant Peptide Hormone Receptor Complex
- 4z5w: The Plant Peptide Hormone Receptor
- 4yzd: Crystal Structure of Human Phosphorylated IRE1ALPHA in Complex with Adp-mg
- 4yzc: Crystal Structure of PIRE1ALPHA in Complex with Staurosporine
- 4yz9: Crystal Structure of Human Phosphorylated IRE1ALPHA in Complex with a Type III Kinase Inhibitor (GSK2850163A)
- 5ajq: Human Lok (stk10) in Complex with Bosutinib
- 4rbl: Crystal Structure of Ser/thr Kinase Pim1 in Complex with Mitoxantrone Derivatives
- 4rc2: Crystal Structure of Ser/thr Kinase Pim1 in Complex with Mitoxantrone Derivatives
- 4rc3: Crystal Structure of Ser/thr Kinase Pim1 in Complex with Mitoxantrone Derivatives
- 4rc4: Crystal Structure of Ser/thr Kinase Pim1 in Complex with Mitoxantrone Derivatives
- 4u8z: Crystal Structure of Mst3 with a Pyrrolopyrimidine Inhibitor (pf- 06447475)
- 4w8d: Crystal Structure of Mst3 with a Pyrrolopyrimidine Inhibitor (pf- 06454589).
- 4w8e: Structure of Mst3 with a Pyrrolopyrimidine Inhibitor (pf-06645342)
- 4ww5: Crystal Structure of Binary Complex Bud32-cgi121 in Complex with Ampp
- 4ww7: Crystal Structure of Binary Complex Bud32-cgi121 in Complex with Amp
- 4ww9: Crystal Structure of Binary Complex Bud32-cgi121 in Complex with Adp
- 4wwa: Crystal Structure of Binary Complex Bud32-cgi121
- 5air: Structural Analysis of Mouse GSK3BETA Fused with Lrp6 Peptide.
- 4ptc: Structure of a Carboxamide Compound (3) (2-{2-[(cyclopropylcarbonyl) Amino]pyridin-4-yl}-4-oxo-4h-1lambda~4~,3-thiazole-5-carboxamide) to GSK3B
- 4pte: Structure of a Carvoxamide Compound (15) (n-[4-(isoquinolin-7-yl) Pyridin-2-yl]cyclopropanecarboxamide) to GSK3B
- 4ptg: Structure of a Carboxamine Compound (26) (2-{2-[(cyclopropylcarbonyl) Amino]pyridin-4-yl}-4-methoxypyrimidine-5-carboxamide) to GSK3B
- 4yve: Rock 1 Bound to Methoxyphenyl Thiazole Inhibitor
- 4yvc: Rock 1 Bound to Thiazole Inhibitor
- 4y8d: Crystal Structure of Cyclin-g Associated Kinase (gak) Complexed with Selective 12i Inhibitor
- 4ykn: PI3K Alpha Lipid Kinase with Active Site Inhibitor
- 4yht: Braf Complexed with an Inhibitor
- 4yg7: Structure of Fl Autorepression Promoter Complex
- 4yfi: TNNI3K Complexed with Inhibitor 1
- 4yff: TNNI3K Complexed with Inhibitor 2
- 4rvt: MAP4K4 in Complex with a Pyridin-2(1h)-one Derivative
- 4wot: Rock2 in Complex with 1426382-07-1
- 4xs2: Irak4-inhibitor Co-structure
- 4y0x: Crystal Structure of The S/t Protein Kinase Pkng from Mycobacterium Tuberculosis in Complex with Adp
- 4y12: Crystal Structure of The S/t Protein Kinase Pkng from Mycobacterium Tuberculosis in Complex with Ags
- 4y73: Crystal Structure of Irak4 Kinase Domain with Inhibitor
- 4yo4: Crystal Structure of Dapk1 Catalytic Domain in Complex with The Hinge Binding Fragment Phthalazine
- 4yo6: Irak4-inhibitor Co-structure
- 4yp8: Irak4-inhibitor Co-structure
- 4ypd: Crystal Structure of Dapk1 Catalytic Domain in Complex with The Hinge Binding Fragment 4-methylpyridazine
- 4yzm: Humanized Roco4 Bound to Lrrk2-in1
- 4yzn: Humanized Roco4 Bound to Compound 19
- 4yzs: Crystal Structures Reveal Transient Perk Luminal Domain Tetramerization in Er Stress Signaling
- 4yzy: Crystal Structures Reveal Transient Perk Luminal Domain Tetramerization in Er Stress Signaling
- 4z7g: Crystal Structure of Human Ire1 Cytoplasmic Kinase-rnase Region - Apo
- 4z7h: Crystal Structure of Human Ire1 Cytoplasmic Kinase-rnase Region - Complex with Imidazopyridine Compound 3
- 5aja: Crystal Structure of Mandrill Samhd1 (amino Acid Residues 1-114) Bound to Vpx Isolated from Mandrill and Human Dcaf1 (amino Acid Residues 1058-1396)
- 2mwc: Solution Structure of Human Obscurin Ig58
- 2n56: Ig59 Domain of Human Obscurin a
- 2n7z: Solution Structure of Rip2 Card
- 2n83: P75NTR Dd:rip2 Card
- 3jbz: Crystal Structure of Mtor Docked into Em Map of Dimeric Atm Kinase
- 3wws: Crystal Structure of Serine/threonine-protein Kinase 3
- 4qeg: Crystal Structure of Domain I10 from Titin (space Group P41)
- 4qml: Mst3 in Complex with Amp-pnp
- 4qmm: Mst3 in Complex with At-9283, 4-[(2-{4-[(cyclopropylcarbamoyl)amino]- 1h-pyrazol-3-yl}-1h-benzimidazol-6-yl)methyl]morpholin-4-ium
- 4qmn: Mst3 in Complex with Bosutinib
- 4qmo: Mst3 in Complex with Imidazolo-oxindole Pkr Inhibitor C16
- 4qmp: Mst3 in Complex with Cdk1/2 Inhibitor Iii, 5-amino-3-{[4- (aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4- Triazole-1-carbothioamide
- 4qmq: Mst3 in Complex with Cp-673451
- 4qms: Mst3 in Complex with Dasatinib
- 4qmt: Mst3 in Complex with Hesperadin
- 4qmu: Mst3 in Complex with Jnj-7706621, 4-({5-amino-1-[(2,6-difluorophenyl) Carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide
- 4qmv: Mst3 in Complex with Pf-03814735, N-{2-[(1s,4r)-6-{[4- (cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4- Tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide
- 4qmw: Mst3 in Complex with Pp-121, 1-cyclopentyl-3-(1h-pyrrolo[2,3- B]pyridin-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine
- 4qmx: Mst3 in Complex with Saracatinib
- 4qmy: Mst3 in Complex with Staurosporine
- 4qmz: Mst3 in Complex with Sunitinib
- 4qna: Mst3 in Complex with 2-(4,6-diamino-1,3,5-triazin-2-yl)phenol
- 4qo9: Mst3 in Complex with Danusertib
- 4r5y: The Complex Structure of Braf V600E Kinase Domain with a Novel Braf Inhibitor
- 4rmz: Crystal Structure of Irak-4
- 4rsv: Human Obscurin Ig58 Domain
- 4rvk: Chk1 Kinase Domain with Diazacarbazole Compound 8: N-[3-(6-cyano-9h- Pyrrolo[2,3-b:5,4-c']dipyridin-3-yl)phenyl]acetamide
- 4rvl: Chk1 Kinase Domain with Diazacarbazole Compound 7: 3-(2- Hydroxyphenyl)-9h-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile
- 4rvm: Chk1 Kinase Domain with Diazacarbazole Compound 19
- 4rzv: Crystal Structure of The Braf (R509H) Kinase Domain Monomer Bound to Vemurafenib
- 4rzw: Crystal Structure of Braf (R509H) Kinase Domain Bound to Az628
- 4tl0: Crystal Structure of Death-associated Protein Kinase 1 with a Crucial Phosphomimicking Mutation
- 4tl6: Crystal Structure of N-terminal Domain of Kaic
- 4tl7: Crystal Structure of N-terminal C1 Domain of Kaic
- 4tl8: Crystal Structure of N-terminal C1 Domain of Kaic
- 4tl9: Crystal Structure of N-terminal C1 Domain of Kaic
- 4tla: Crystal Structure of N-terminal C1 Domain of Kaic
- 4tlb: Crystal Structure of N-terminal C1 Domain of Kaic
- 4tlc: Crystal Structure of N-terminal C1 Domain of Kaic
- 4tld: Crystal Structure of N-terminal C1 Domain of Kaic
- 4tle: Crystal Structure of N-terminal C1 Domain of Kaic
- 4tn6: CK1D in Complex with Inhibitor
- 4tyh: Ternary Complex of P38 and Mk2 with a P38 Inhibitor
- 4u3y: Apo Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
- 4u3z: Apo MAP4K4 T181E Phosphomimetic Mutant
- 4u40: Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Bound to Amppnp
- 4u41: MAP4K4 Bound to Inhibitor Compound 1
- 4u42: MAP4K4 T181E Mutant Bound to Inhibitor Compound 1
- 4ub7: High-salt Structure of Protein Kinase Ck2 Catalytic Subunit with 4'- Carboxy-6,8-bromo-flavonol (flc26) Showing an Extreme Distortion of The Atp-binding Loop Combined with a Pi-halogen Bond
- 4uba: Low-salt Structure of Protein Kinase Ck2 Catalytic Subunit with 4'- Carboxy-6,8-bromo-flavonol (flc26)
- 4usd: Human Stk10 (lok) with Sb-633825
- 4use: Human Stk10 (lok) with Sb-633825
- 4usf: Human Slk with Sb-440719
- 4uv0: Structure of a Semisynthetic Phosphorylated Dapk
- 4wua: Crystal Structure of Human Srpk1 Complexed to an Inhibitor Srpin340
- 4wzx: Ulk3 Regulates Cytokinetic Abscission by Phosphorylating Escrt-iii Proteins
- 4xbr: In Cellulo Crystal Structure of Pak4 in Complex with Inka
- 4xbu: In Vitro Crystal Structure of Pak4 in Complex with Inka Peptide
- 4xh0: Structure of C. Glabrata Hrr25 Bound to Adp (so4 Condition)
- 4xh6: Crystal Structure of Proto-oncogene Kinase Pim1 Bound to Hispidulin
- 4xhl: Structure of S. Cerevisiae Hrr25 1-394 (K38R Mutant)
- 4xv1: B-raf Kinase V600E Oncogenic Mutant in Complex with Plx7904
- 4xv2: B-raf Kinase V600E Oncogenic Mutant in Complex with Dabrafenib
- 4xv3: B-raf Kinase V600E Oncogenic Mutant in Complex with Plx7922
- 4xv9: B-raf Kinase Domain in Complex with Plx5568
- 4xx5: Structure of PI3K Gamma in Complex with an Inhibitor
- 4xx9: Crystal Structure of Pdk1 in Complex with Atp and The Pif-pocket Ligand Rf4
- 4xz4: Structure of PI3K Gamma in Complex with an Inhibitor
- 6lph: The Sufu-fu Complex Crystal Structure
- 6wjq: Crystal Structure of Wdr5 in Complex with The Win Peptide of Pdpk1
- 6xgu: Crystal Structure of KRAS-Q61R (gmppnp-bound) in Complex with Ras- Binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf
- 6xgv: Crystal Structure of KRAS-G13D (gmppnp-bound) in Complex with Ras- Binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf
- 6xha: Crystal Structure of KRAS-G12V (gmppnp-bound) in Complex with Ras- Binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf
- 6xhb: Crystal Structure of Wild-type Kras (gmppnp-bound) in Complex with Ras-binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf (crystal Form Ii)
- 6xi7: Crystal Structure of Wild-type Kras (gmppnp-bound) in Complex with Ras-binding Domain (rbd) and Cysteine-rich Domain (crd) of Raf1/craf (crystal Form I)
- 7ayh: Crystal Structure of Aurora a in Complex with 7-(2-anilinopyrimidin-4- Yl)-1-benzazepin-2-one Derivative (compound 2c)
- 7ayi: Crystal Structure of Aurora a in Complex with 7-(2-anilinopyrimidin-4- Yl)-1-benzazepin-2-one Derivative (compound 2a)
- 7ccu: Crystal Structure of Death-associated Protein Kinase 1 in Complex with Resveratrol
- 7ccv: Crystal Structure of Death-associated Protein Kinase 1 in Complex with Piceatannol
- 7ccw: Crystal Structure of Death-associated Protein Kinase 1 in Complex with Resveratrol and Mes
- 7k0y: Cryo-em Structure of Activated-form Dna-pk (complex Vi)
- 7k10: Cryoem Structure of Activated-form Fatkin Domain of Dna-pk
- 7k11: Cryoem Structure of Inactivated-form Fatkin Domain of Dna-pk
- 7k17: Re-refined Crystal Structure of Dna-dependent Protein Kinase Catalytic Subunit Complexed with Ku80 C-terminal Helix
- 7k19: Cryoem Structure of Dna-pk Catalytic Subunit Complexed with Dna (complex I)
- 7k1b: Cryoem Structure of Dna-pk Catalytic Subunit Complexed with Dna (complex Ii)
- 7k1j: Cryoem Structure of Inactivated-form Dna-pk (complex Iii)
- 7k1k: Cryoem Structure of Inactivated-form Dna-pk (complex Iv)
- 7k1n: Cryoem Structure of Inactivated-form Dna-pk (complex V)
- 7k6m: Crystal Structure of PI3KALPHA Selective Inhibitor Pf-06843195
- 7k6n: Crystal Structure of PI3KALPHA Selective Inhibitor 11-1575
- 7k6o: Crystal Structure of PI3KALPHA Inhibitor 10-5429
- 7k71: Crystal Structure of PI3KALPHA Inhibitor 4-0686
- 7kac: Crystal Structure of Hpk1 (MAP4K1) Kinase in Complex with 5-{[4- {[(1s)-2-hydroxy-1-phenylethyl]amino}-5-(1,3,4-oxadiazol-2-yl) Pyrimidin-2-yl]amino}-3,3-dimethyl-2-benzofuran-1(3h)-one
- 7jjh: Crystal Structure of The Unliganded Tandem Bromodomain (bd1, Bd2) of Human Taf1
- 6vo7: Crystal Structure of PI3K-ALPHA Ras Binding Domain (rbd)
- 7b8h: Monoclinic Structure of Human Protein Kinase Ck2 Catalytic Subunit in Complex with a Heparin Oligo Saccharide
- 7b8i: Tetragonal Structure of Human Protein Kinase Ck2 Catalytic Subunit in Complex with a Heparin Oligo Saccharide
- 6vqm: Crystal Structure Analysis of Human Ack1
- 6wqx: Human Prpk-tprkb Complex
- 6vxu: Structure of Human Vaccinia-related Kinase 1 (vrk1) Bound to Ach471
- 7ncf: Crystal Structure of Hipk2 in Complex with Mu135 (compound 21e)
- 7nip: Titin N2A Unique Sequence (UN2A) Core
- 7b1f: Orthorhombic P212121 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 Cd1 Domain
- 7b1h: Monoclinic P21 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 Cd1 Domain
- 7b1j: Orthorhombic P21212 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 Cd1 Domain
- 7e2k: Crystal Structure of The Rwd Domain of Human Gcn2 - 1
- 7e2m: Crystal Structure of The Rwd Domain of Human Gcn2 - 2
- 7jwe: Gedatolisib Bound to The PI3KG Catalytic Subunit P110 Gamma
- 7jwz: Ipi-549 Bound to The PI3KG Catalytic Subunit P110 Gamma
- 7jx0: Nvs-pi3-4 Bound to The PI3KG Catalytic Subunit P110 Gamma
- 7l24: Hpk1 in Complex with Compound 11
- 7l25: Hpk1 in Complex with Compound 18
- 7l26: Hpk1 in Complex with Compound 38
- 6z1c: Crystal Structure of Arabidopsis Thaliana Ck2-alpha-1 in Complex with Ttp-22
- 7ahs: TITIN-N2A Ig81-ig83
- 7kke: Phosphoinositide 3-kinase Gamma Bound to a Thiazole Inhibitor
- 6l23: Crystal Structure of CK2A1 V116I with Hematein
- 6ygn: Titin Kinase and Its Flanking Domains
- 7bu4: Crystal Structure of CK2A1 Complexed with Ky49
- 7m0k: Hpk1 in Complex with Compound 1
- 7m0l: Hpk1 in Complex with Compound 1
- 7m0m: Hpk1 in Complex with Compound 1
- 6yj0: Solution Nmr Structure of Titin N2A Region Ig Domain I83
- 7akm: Crystal Structure of Chk1 Kinase Domain in Complex with Atpys
- 7ako: Crystal Structure of Chk1 Kinase Domain in Complex with a Claspin Phosphopeptide
- 7lt3: Nhej Long-range Synaptic Complex
- 6xdb: Crystal Structure of IRE1A in Complex with G-6904
- 6xdd: Crystal Structure of Ire1 in Complex with G-3053
- 6xdf: Crystal Structure of IRE1A in Complex with G-4100
- 7aby: Crystal Structure of ILOV-Q489K Mutant
- 7dd1: Crystal Structure of Srpk1 in Complex with a Peptide Inhibitor
- 7m0t: Crystal Structure of The Braf:mek1 Kinases in Complex with Amppnp and Selumetinib
- 7m0u: Crystal Structure of The Braf:mek1 Kinases in Complex with Amppnp and Binimetinib
- 7m0v: Crystal Structure of The Braf:mek1 Kinases in Complex with Amppnp and Cobimetinib
- 7m0w: Crystal Structure of The Braf:mek1 Kinases in Complex with Amppnp and Pimasertib
- 7m0x: Crystal Structure of The Braf:mek1 Kinases in Complex with Amppnp and Pd0325901
- 7m0y: Crystal Structure of The Braf:mek1 Kinases in Complex with Amppnp and Trametinib
- 7m0z: Crystal Structure of The Braf:mek1 Kinases in Complex with Amppnp and Ch5126766
- 7da4: Cryo-em Structure of Amyloid Fibril Formed by Human Ripk3
- 7dac: Human Ripk3 Amyloid Fibril Revealed by Solid-state Nmr
- 7edx: P53-bound Tfiid-based Core Pic on Hdm2 Promoter
- 7eg7: Tfiid-based Core Pic on Scp Promoter
- 7eg8: Tfiid-based Core Pic on Puma Promoter
- 7eg9: Tfiid-based Intermediate Pic on Scp Promoter
- 7ega: Tfiid-based Intermediate Pic on Puma Promoter
- 6zv6: Human Rio1(kd)-stha Late Pre-40s Particle, Structural State B (post 18s Rrna Cleavage)
- 7egd: Scp Promoter-bound Tfiid-tfiia in Initial Tbp-loading State
- 7ege: Tfiid in Canonical Conformation
- 7egh: Tfiid Lobe C Subcomplex
- 7egi: Tfiid in Rearranged Conformation
- 7egj: Scp Promoter-bound Tfiid-tfiia in post Tbp-loading State
- 6yzh: Crystal Structure of P8C9 Bound to CK2ALPHA
- 7jxx: Structure of Ttbk1 Kinase Domain in Complex with Compound 3
- 7jxy: Structure of Ttbk1 Kinase Domain in Complex with Compound 18
- 7oai: Crystal Structure of Pseudokinase Cask in Complex with Pfe-pkis12
- 7oaj: Crystal Structure of Pseudokinase Cask in Complex with Compound 7
- 7oak: Crystal Structure of Pseudokinase Cask in Complex with Compound 26
- 7oal: Crystal Structure of Pseudokinase Cask in Complex with Compound 25
- 6z19: Crystal Structure of P8C9 Bound to CK2ALPHA
- 7k0v: Crystal Structure of Braf in Complex with Inhibitor Gne-0749
- 7m10: Phf2 Phd Domain Complexed with Peptide from N-terminus of Vrk1
- 6x61: Crystal Structure of The N-terminal Thioredoxin Domain of Sasa in Complex with The N-terminal Ci Domain of Kaic from Thermosynchococcus Elongatus
- 6xaf: 1.9a Crystal Structure of The Gtpase Domain of Parkinson's Disease- Associated Protein Lrrk2 Carrying R1398H
- 7n42: Crystal Structure of The Tandem Bromodomain of Human Taf1 (taf1-t) Bound to Zs1-681
- 7lht: Structure of The Lrrk2 Dimer
- 7lhw: Structure of The Lrrk2 Monomer
- 7li3: Structure of The Lrrk2 G2019S Mutant
- 7li4: Structure of Lrrk2 after Symmetry Expansion
- 7mck: Structure of Chk1 10-pt. Mutant Complex with Lrrk2 Inhibitor 18
- 7jiu: Human PI3KDELTA in Complex with Compound 2f
- 7l6x: Crystal Structure of The Tandem Bromodomain (bd1, Bd2) of Human Taf1 Bound to Gne-371
- 7bjd: Crystal Structure of Chk1-10pt-mutant Complex with Compound 3
- 7bje: Crystal Structure of Chk1-10pt-mutant Complex with Adenine
- 7bjh: Crystal Structure of Chk1-10pt-mutant Complex with Compound 8
- 7bjj: Crystal Structure of Chk1-10pt-mutant Complex with Compound 9
- 7bjm: Crystal Structure of Chk1-10pt-mutant Complex with Compound 10
- 7bjo: Crystal Structure of Chk1-10pt-mutant Complex with Compound 13
- 7bjr: Crystal Structure of Chk1-10pt-mutant Complex with Compound 18
- 7bjx: Crystal Structure of Chk1-10pt-mutant Complex with Compound 26
- 7bk1: Crystal Structure of Chk1-10pt-mutant Complex with Compound 32
- 7bk2: Crystal Structure of Chk1-10pt-mutant Complex with Compound 44
- 7bk3: Crystal Structure of Chk1-10pt-mutant Complex with Compound 45
- 7bkn: Crystal Structure of Chk1 Complex with Adenine
- 7bko: Crystal Structure of Chk1 Complex with Compound 9
- 7cjb: Vhl Recognizes Hydroxyproline in Ripk1
- 7lb0: Crystal Structure of The Tandem Bromodomain (bd1, Bd2) of Human Taf1 Bound to Zs1-295
- 7lb1: Crystal Structure of The Tandem Bromodomain (bd1, Bd2) of Human Taf1 Bound to Zs1-585
- 7lb2: Crystal Structure of The Tandem Bromodomain (bd1, Bd2) of Human Taf1 Bound to Zs1-589
- 7mez: Structure of The Phosphoinositide 3-kinase P110 Gamma (PIK3CG) P101 (PIK3R5) Complex
- 7p1l: The Mark3 Kinase Domain Bound to Aa-cs-1-008
- 6zx9: Crystal Structure of Siv Vpr,fused to T4 Lysozyme, Isolated from Moustached Monkey, Bound to Human Ddb1 and Human Dcaf1 (amino Acid Residues 1046-1396)
- 7jhg: Cryo-em Structure of Atp-bound Fully Inactive Ampk in Complex with Dorsomorphin (compound C) and Fab-nanobody
- 7jhh: Cryo-em Structure of Atp-bound Fully Inactive Ampk in Complex with Fab and Nanobody
- 7ops: Crystal Structure of Haspin in Complex with Zw282 (compound 2a)
- 6zue: Crystal Structure of Human Ddb1 Bound to Human Dcaf1 (amino Acid Residues 1046-1396)
- 7cmb: Crystal Structure of Pak4 in Complex with Inhibitor 41
- 7jij: Atp-bound Amp-activated Protein Kinase
- 7jjg: Crystal Structure of The Second Bromodomain (bd2) of Human Taf1 Bound to Atr Kinase Inhibitor Az20
- 7lvh: Crystal Structure of Ap2 Associated Kinase 1 Isoform 1 Complexed with Ligand N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-3-(propan-2-yl) Piperidine-2-carboxamide
- 7lvi: Crystal Structure of Ap2 Associated Kinase 1 Isoform 1 Complexed with Ligand (2r)-2-amino-n-[3-methoxy-4- (1,3-oxazol-5-yl)phenyl]-4- Methylpentanamide
- 7at5: Structure of Protein Kinase Ck2 Catalytic Subunit (CSNK2A1 Gene Product) in Complex with The Bivalent Inhibitor Kn2
- 7at9: Structure of Protein Kinase Ck2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with The Atp-competitive Inhibitor Mb002 and The Alphad-pocket Ligand 3,4-dichlorophenethylamine
- 7atv: Structure of Protein Kinase Ck2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with The Bivalent Inhibitor Kn2
- 7naa: Crystal Structure of Mycobacterium Tuberculosis H37RV Pknf Kinase Domain
- 7oov: Crystal Structure of Pim1 in Complex with Arc-1411
- 7oow: Crystal Structure of Pim1 in Complex with Arc-1415
- 7oox: Crystal Structure of Pim1 in Complex with Arc-3126
- 7cp3: Crystal Structure of Pak4 in Complex with Inhibitor 47
- 7cp4: Crystal Structure of Pak4 in Complex with Inhibitor 55
- 7l1x: Structure of Human Ck2 Alpha Kinase (catalytic Subunit) with The Inhibitor 108600.
- 7lwh: Human Neurofibromin 2/merlin Residues 1-339 in Complex with Lats1
- 7f3g: Crystal Structure of Dclk1 Kinase Domain in Complex with Ruxolitinib
- 7nfc: Cryo-em Structure of Nhej Super-complex (dimer)
- 7nfe: Cryo-em Structure of Nhej Super-complex (monomer)
- 7apj: Structure of Autoinhibited Akt1 Reveals Mechanism of Pip3-mediated Activation
- 7jsp: Crystal Structure of The Second Bromodomain (bd2) of Human Taf1 Bound to Atr Kinase Inhibitor Azd6738
- 7jtc: Crystal Structure of The Second Bromodomain (bd2) of Human Taf1 Bound to Zs1-322
- 7ni4: Human Atm Kinase Domain with Bound M4076 Inhibitor
- 7ni5: Human Atm Kinase with Bound Inhibitor Ku-55933
- 7ni6: Human Atm Kinase with Bound Atpys
- 7nh4: Co-crystal Structure of Akt1 in Complex with Covalent-allosteric Akt Inhibitor 3
- 7nh5: Co-crystal Structure of Akt1 in Complex with Covalent-allosteric Akt Inhibitor 6
- 7owg: Human Deptor in a Complex with Mutant Human Mtorc1 A1459P
- 7pe8: Cryo-em Structure of Deptor Bound to Human Mtor Complex 2, Focussed on One Protomer
- 7pe9: Cryo-em Structure of Deptor Bound to Human Mtor Complex 2, Dept-bound Subset Local Refinement
- 7pea: Cryo-em Structure of Deptor Bound to Human Mtor Complex 1, Overall Refinement
- 7peb: Cryo-em Structure of Deptor Bound to Human Mtor Complex 1, Focussed on One Protomer
- 7pec: Cryo-em Structure of Deptor Bound to Human Mtor Complex 1, Dept-bound Subset Local Refinement
- 7o3b: Crystal Structure of The Ttbk2-cep164 Complex Bound to a Camelid Nanobody
- 7pe7: Cryo-em Structure of Deptor Bound to Human Mtor Complex 2, Overall Refinement
- 7k03: Crystal Structure of The Tandem Bromodomain (bd1 and Bd2) of Human Taf1 Bound to Atr Kinase Inhibitor Azd6738
- 7k0d: Crystal Structure of The Tandem Bromodomain (bd1, Bd2) of Human Taf1 Bound to Mtorc1/2 Inhibitor Azd3147
- 7k0u: Crystal Structure of The Second Bromodomain (bd2) of Human Taf1 Bound to Plk1 Kinase Inhibitor Bi2536
- 7k1p: Crystal Structure of The Second Bromodomain (bd2) of Human Taf1 Bound to Bromosporine
- 7k27: Crystal Structure of The Tandem Bromodomain (bd1, Bd2) of Human Taf1 Bound to Atr Inhibitor Az20
- 7k3o: Crystal Structure of The Unliganded Second Bromodomain (bd2) of Human Taf1
- 7k42: Crystal Structure of The Second Bromodomain (bd2) of Human Taf1 Bound to Dioxane
- 7k6f: Crystal Structure of The Tandem Bromodomain (bd1, Bd2) of Human Taf1 in Complex with Mes (2-(n-morpholino)ethanesulfonic Acid)
- 7kx6: Crystal Structure of Dclk1-kd in Complex with Xmd8-85
- 7kx8: Crystal Structure of Dclk1-cter in Complex with Fmf-03-055-1
- 7kxw: Crystal Structure of Dclk1-kd in Complex with Dclk1-in-1
- 7o86: 1.73a X-ray Crystal Structure of The Conserved C-terminal (cct) of Human Spak
- 7okw: 1.62a X-ray Crystal Structure of The Conserved C-terminal (cct) of Human Osr1
- 7s65: Compressed Conformation of Nighttime State Kaic
- 7s66: Extended Conformation of Nighttime State Kaic
- 7s67: Extended Conformation of Daytime State Kaic
- 7bmk: Atp-competitive Partial Antagonists-'pair's-rheostatically Modulate IRE1ALPHA'S Kinase Helix-alphac to Segregate Its Rnase-mediated Biological Outputs
- 7okq: Cryo-em Structure of The DDB1-DCAF1-CUL4A-RBX1 Complex
- 7p4s: Bromodomain of Human Taf1 (2) with Naphthyridinone Compound
- 7o2v: Aurora Kinase a in Complex with The Aur-a/pdk1 Inhibitor Vi8
- 6xrn: Crystal Structure of Human PI3K-GAMMA in Complex with Compound 17
- 7p3v: B-raf V600E Structure Bound to a New Inhibitor
- 7mgj: TNNI3K Complexed with N-methyl-4-(4-(3-(3-(trifluoromethyl) Phenyl) Ureido) Phenoxy)picolinamide
- 7mgk: TNNI3K Complexed with 1-(3,5-dichloro-4-((6-(methylamino)pyrimidin-4- Yl)oxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
- 7myn: Cryo-em Structure of P110ALPHA in Complex with P85ALPHA
- 7myo: Cryo-em Structure of P110ALPHA in Complex with P85ALPHA Inhibited by Byl-719
- 7mon: Structure of Human Ripk3-mlkl Complex
- 7ay9: Crystal Structure of Ck2 Bound by Compound 7
- 7aya: Crystal Structure of Ck2 Bound by Compound 9
- 7mx3: Crystal Structure of Human Ripk3 Complexed with Gsk'843
- 7o7i: Crystal Structure of The Human Hipk3 Kinase Domain
- 7o7j: Crystal Structure of The Human Hipk3 Kinase Domain Bound to Abemaciclib
- 7pue: Human Serum and Glucocorticoid-regulated Kinase 1 in Complex with Pyrazolopyridine Inhibitor 3a
- 7pw4: Human Smg1-8-9 Kinase Complex Bound to a Smg1 Inhibitor
- 7pw5: Human Smg1-8-9 Kinase Complex with Alphafold Predicted Smg8 C- Terminus, Bound to a Smg1 Inhibitor
- 7pw6: Human Smg1-8-9 Kinase Complex Bound to a Smg1 Inhibitor - Smg1 Body
- 7pw7: Human Smg1-9 Kinase Complex Bound to a Smg1 Inhibitor
- 7pw8: Human Smg1-8-9 Kinase Complex Bound to Amppnp
- 7pw9: Human Smg1-9 Kinase Complex Bound to Amppnp
- 7m74: Atp-bound Amp-activated Protein Kinase
- 7pqs: Srpk1 in Complex with Msc2711186
- 7sse: Crystal Structure of The Wdr Domain of Human Dcaf1 in Complex with Cyca-117-70
- 7qhg: Lim Domain Kinase 2 (limk2) in Complex with Th-470
- 7t3x: Structure of Unphosphorylated Pediculus Humanus (ph) Pink1 D334A Mutant
- 7sqm: Discovery and Preclinical Pharmacology of Ine963, a Potent and Fast- Acting Blood-stage Antimalarial with a High Barrier to Resistance and Potential for Single-dose Cure in Uncomplicated Malaria
- 7r9l: Crystal Structure of Hpk1 in Complex with Compound 2
- 7r9n: Crystal Structure of Hpk1 in Complex with Gne1858
- 7r9p: Crystal Structure of Hpk1 in Complex with Compound 14
- 7r9t: Crystal Structure of Hpk1 in Complex with Compound 17
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