EC 2.7.11.23 - ATP:[DNA- directed RNA polymerase] phosphotransferase ([RNA- polymerase] - subunit kinase)

3D structures of EC 2.7.11.23 - [RNA-polymerase]-subunit kinase in Protein Data Bank

updated: 6 January 2022, 2:15

1. 3my1: Structure of Cdk9/cyclint1 in Complex with Drb
2. 3mia: Crystal Structure of Hiv-1 Tat Complexed with Atp-bound Human P-tefb
3. 3mi9: Crystal Structure of Hiv-1 Tat Complexed with Human P-tefb
4. 3blr: Crystal Structure of Human Cdk9/cyclint1 in Complex with Flavopiridol
5. 3blq: Crystal Structure of Human Cdk9/cyclint1 in Complex with Atp
6. 3blh: Crystal Structure of Human Cdk9/cyclint1
7. 6z45: Cdk9-cyclin-t1 Complex Bound by Compound 24
8. 6b3e: Crystal Structure of Human Cdk12/cyclink in Complex with an Inhibitor
9. 6t41: Cdk8/cyclin C in Complex with N-(4-chlorobenzyl)isoquinolin-4-amine
10. 6xd3: Structure of The Human Cak in Complex with Thz1
11. 6xbz: Structure of The Human Cdk-activating Kinase
12. 6xi8: Yeast Tfiik (kin28/ccl1/tfb3) Complex
13. 6tpa: Cdk8/cyclinc in Complex with Drug Etp-50775
14. 6td3: Structure of Ddb1 Bound to Cr8-engaged Cdk12-cyclink
15. 3lq5: Structure of Cdk9/cyclint in Complex with S-cr8
16. 6r3s: Crystal Structure of Cdk8-cycc in Complex with Compound 1
17. 6qtj: Crystal Structure of Human Cdk8/cycc in Complex with Bi 919811
18. 6qtg: Crystal Structure of Human Cdk8/cycc in Complex with Bi-1347
19. 3rgf: Crystal Structure of Human Cdk8/cycc
20. 3tn8: Cdk9/cyclin T in Complex with Can508
21. 3tnh: Cdk9/cyclin T in Complex with Can508
22. 3tni: Structure of Cdk9/cyclin T F241L
23. 6o9l: Human Holo-pic in The Closed State
24. 4ec8: Structure of Full Length Cdk9 in Complex with Cyclint and Drb
25. 4ec9: Crystal Structure of Full-length Cdk9 in Complex with Cyclin T
26. 4bcf: Structure of Cdk9 in Complex with Cyclin T and a 2-amino-4- Heteroaryl-pyrimidine Inhibitor
27. 4bch: Structure of Cdk9 in Complex with Cyclin T and a 2-amino-4- Heteroaryl-pyrimidine Inhibitor
28. 4bci: Structure of Cdk9 in Complex with Cyclin T and a 2-amino-4- Heteroaryl-pyrimidine Inhibitor
29. 4bcj: Structure of Cdk9 in Complex with Cyclin T and a 2-amino-4- Heteroaryl-pyrimidine Inhibitor
30. 4bcg: Structure of Cdk9 in Complex with Cyclin T and a 2-amino-4- Heteroaryl-pyrimidine Inhibitor
31. 6gzh: Crystal Structure of Human Cdk9/cyclint1 with A86
32. 6gu7: Cdk1/cks2 in Complex with Azd5438
33. 6gu6: Cdk1/cks2 in Complex with Dinaciclib
34. 6gu4: Cdk1/cyclinb/cks2 in Complex with CGP74514A
35. 6gu3: Cdk1/cyclinb/cks2 in Complex with Azd5438
36. 6gu2: Cdk1/cyclinb/cks2 in Complex with Flavopiridol
37. 4imy: The Aff4 Scaffold Binds Human P-tefb Adjacent to Hiv Tat
38. 4f6s: Crystal Structure of Human Cdk8/cycc in Complex with Compound 7 (1-[3- Tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea)
39. 4f6u: Crystal Structure of Human Cdk8/cycc in Complex with Compound 5 (1-[3- Tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-[3-(morpholin-4-yl) Propyl]urea)
40. 4f6w: Crystal Structure of Human Cdk8/cycc in Complex with Compound 1 (n-[3- Tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-4-[2-({[3-tert-butyl- 1-(4-methylphenyl)-1h-pyrazol-5-yl]carbamoyl}amino)ethyl]piperazine- 1-carboxamide)
41. 4f70: Crystal Structure of Human Cdk8/cycc in Complex with Compound 4 (1-[3- Tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-[2-(morpholin-4-yl) Ethyl]urea)
42. 4f7j: Crystal Structure of Human Cdk8/cycc in Complex with Compound 3 (1-[3- Tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-(2-hydroxyethyl) Urea)
43. 4f7l: Crystal Structure of Human Cdk8/cycc in Complex with Compound 2 (tert- Butyl [3-({[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5- Yl]carbamoyl}amino)propyl]carbamate)
44. 4f7n: Crystal Structure of Human Cdk8/cycc in Complex with Compound 11 (1- [3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-(5- Hydroxypentyl)urea)
45. 4f7s: Crystal Structure of Human Cdk8/cycc in The Dmg-in Conformation
46. 4g6l: Crystal Structure of Human Cdk8/cycc in The Dmg-in Conformation
47. 6cyt: Hiv-1 Tar Loop in Complex with Tat:aff4:p-tefb
48. 6ckx: Structure of Cdk12/cyck in Complex with a Small Molecule Inhibitor N- (4-(1-methyl-1h-pyrazol-4-yl)phenyl)-n-((1r,4r)-4-(quinazolin-2- Ylamino)cyclohexyl)acetamide
49. 4cfn: Structure-based Design of C8-substituted O6-cyclohexylmethoxyguanine Cdk1 and 2 Inhibitors.
50. 4cfw: Structure-based Design of C8-substituted O6- Cyclohexylmethoxyguanine Cdk1 and 2 Inhibitors.
51. 4nst: Crystal Structure of Human Cdk12/cyclin K in Complex with Adp-aluminum Fluoride
52. 4ogr: Crystal Structure of P-tefb Complex with Aff4 and Tat
53. 4or5: Crystal Structure of Hiv-1 Tat Complexed with Human P-tefb and Aff4
54. 5xs2: Cdk8-cycc in Complex with Compound 17:3-chloro-4-(4-pyridyl)-1h- Pyrrole-2-carboxamide
55. 5xqx: Human Cdk8-cycc in Complex with Compound 4: N-methyl-4-(4-pyridyl)-1h- Pyrrole-2-carboxamide
56. 4cfm: Structure-based Design of C8-substituted O6- Cyclohexylmethoxyguanine Cdk1 and 2 Inhibitors.
57. 4cfu: Structure-based Design of C8-substituted O6- Cyclohexylmethoxyguanine Cdk1 and 2 Inhibitors.
58. 4cfv: Structure-based Design of C8-substituted O6- Cyclohexylmethoxyguanine Cdk1 and 2 Inhibitors.
59. 4cfx: Structure-based Design of C8-substituted O6-cyclohexylmethoxyguanine Cdk1 and 2 Inhibitors.
60. 5lqf: Cdk1/cyclinb1/cks2 in Complex with Nu6102
61. 5l1z: Tar Complex with Hiv-1 Tat-aff4-p-tefb
62. 5idp: Cdk8-cycc in Complex with (3-amino-1h-indazol-5-yl)-[(s)-2-(4-fluoro- Phenyl)-piperidin-1-yl]-methanone
63. 5idn: Cdk8-cycc in Complex with [(s)-2-(4-chloro-phenyl)-pyrrolidin-1-yl]- (3-methyl-1h-pyrazolo[3,4-b]pyridin-5-yl)-methanone
64. 5icp: Cdk8-cycc in Complex with [(s)-2-(4-chloro-phenyl)-pyrrolidin-1-yl]- (5-methyl-imidazo[5,1-b][1,3,4]thiadiazol-2-yl)-methanone
65. 5i5z: Cdk8-cycc in Complex with 8-(1-methyl-2,2-dioxo-2,3-dihydro-1h-2l6- Benzo[c]isothiazol-5-yl)-[1,6]naphthyridine-2-carboxylic Acid Methylamide
66. 5hvy: Cdk8/cycc in Complex with Compound 20
67. 5hq0: Ternary Complex of Human Proteins Cdk1, Cyclin B and Cks2, Bound to an Inhibitor
68. 5hnb: Cdk8-cycc in Complex with [6-hydroxy-3-(3-methyl-benzyl)-1h-indazol-5- Yl]-((s)-3-hydroxy-pyrrolidin-1-yl)-methanone
69. 5hbj: Cdk8-cycc in Complex with 8-[2-amino-3-chloro-5-(1-methyl-1h-indazol- 5-yl)-pyridin-4-yl]-2,8-diaza-spiro[4.5]decan-1-one
70. 5hbh: Cdk8-cycc in Complex with 5-{5-chloro-4-[1-(2-methoxy-ethyl)-1,8- Diaza-spiro[4.5]dec-8-yl]-pyridin-3-yl}-1-methyl-1,3-dihydro- Benzo[c]isothiazole 2,2-dioxide
71. 5hbe: Cdk8-cycc in Complex with 8-[3-chloro-5-(1-methyl-2,2-dioxo-2, 3- Dihydro-1h-2l6-benzo[c]isothiazol-5-yl)-pyridin- 4-yl]-1-oxa-3,8- Diaza-spiro[4.5]decan-2-one
72. 5fgk: Cdk8-cycc in Complex with 8-[3-(3-amino-1h-indazol-6-yl)-5-chloro- Pyridine-4-yl]-2,8-diaza-spiro[4.5]decan-1-one
73. 5efq: Crystal Structure of Human Cdk13/cyclin K in Complex with Adp-aluminum Fluoride
74. 5cei: Crystal Structure of Cdk8:cyclin C Complex with Compound 22
75. 5bnj: Cdk8/cycc in Complex with 8-{3-chloro-5-[4-(1-methyl-1h-pyrazol-4-yl)- Phenyl]-pyridin- 4-yl}-2,8-diaza-spiro[4.5]decan-1-one
76. 4yc3: Cdk1/cyclinb1/cks2 Apo
77. 4yc6: Cdk1/cks1
78. 4y72: Human Cdk1/cyclinb1/cks2 with Inhibitor
79. 7jv7: Crystal Structure of The Yeast Rna Pol II Ctd Kinase Ctdk-1 Complex
80. 7kpv: Structure of Kinase and Central Lobes of Yeast Ckm
81. 7kpx: Structure of The Yeast Ckm
82. 7b5o: Cryo-em Structure of The Human Cak Bound to Icec0942 at 2.5 Angstroms Resolution
83. 7b5q: Cryo-em Structure of The Human Cak Bound to Icec0942 (PHENIX-OPLS3E)
84. 6y0a: Crystal Structure of Cdk8-cycc in Complex with Bi00690300
85. 7kue: Cryoem Structure of Yeast Tfiik (kin28/ccl1/tfb3) Complex
86. 7nvr: Human Mediator with Rna Polymerase II Pre-initiation Complex
87. 6twn: Crystal Structure of Talin1 R7R8 in Complex with Cdk1 (206-223)
88. 7nxj: Crystal Structure of Human Cdk13/cyclin K in Complex with The Inhibitor Thz531
89. 7nxk: Crystal Structure of Human Cdk12/cyclin K in Complex with The Inhibitor Bsj-01-175
90. 7nj0: Cryoem Structure of The Human Separase-cdk1-cyclin B1-cks1 Complex
91. 6w9e: Crystal Structure of Human Cdk9/cyclint1 in Complex with Mc180295
92. 7nwk: Crystal Structure of Cdk9-cyclin T1 Bound by Compound 6