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enzyme (lysozyme)

 
Enzymes
  Enzyme classes:
  EC 1: Oxidoreductases
  EC 2: Transferases
    EC 2.1
    EC 2.2
    EC 2.3
    EC 2.4
    EC 2.5
    EC 2.6
    EC 2.7
      EC 2.7.1
      EC 2.7.2
      EC 2.7.3
      EC 2.7.4
      EC 2.7.5
      EC 2.7.6
      EC 2.7.7
      EC 2.7.8
      EC 2.7.9
      EC 2.7.10
      EC 2.7.11
        EC 2.7.11.1
        EC 2.7.11.2
        EC 2.7.11.3
        EC 2.7.11.4
        EC 2.7.11.6
        EC 2.7.11.7
        EC 2.7.11.8
        EC 2.7.11.9
        EC 2.7.11.10
        EC 2.7.11.11
        EC 2.7.11.12
        EC 2.7.11.13
        EC 2.7.11.14
        EC 2.7.11.15
        EC 2.7.11.16
        EC 2.7.11.17
        EC 2.7.11.18
        EC 2.7.11.19
        EC 2.7.11.20
        EC 2.7.11.21
        EC 2.7.11.22
        EC 2.7.11.23
        EC 2.7.11.24
        EC 2.7.11.25
        EC 2.7.11.26
        EC 2.7.11.27
        EC 2.7.11.28
        EC 2.7.11.29
        EC 2.7.11.30
        EC 2.7.11.31
      EC 2.7.12
      EC 2.7.13
      EC 2.7.14
    EC 2.8
    EC 2.9
  EC 3: Hydrolases
  EC 4: Lyases
  EC 5: Isomerases
  EC 6: Ligases
  General information:
  Catalytic mechanism
  Enzyme kinetics
  Inhibitors
  Enzymes in industry

EC 2.7.11.11 - ATP:protein phosphotransferase (cAMP- dependent) (cAMP- dependent protein kinase)



3D structures of EC 2.7.11.11 - cAMP-dependent protein kinase in Protein Data Bank

updated: 29 May 2015, 1:12

In total: 119 PDB structures of EC 2.7.11.11 - cAMP-dependent protein kinase:
  1. 3ow3: Discovery of Dihydrothieno- and Dihydrofuropyrimidines as Potent Pan Akt Inhibitors
  2. 3o7l: Crystal Structure of Phospholamban (1-19):pka C-subunit:amp-pnp:mg2+ Complex
  3. 3mvj: Human Cyclic Amp-dependent Protein Kinase Pka Inhibitor Complex
  4. 3idc: Crystal Structure of (102-265)riib:c Holoenzyme of Camp- Dependent Protein Kinase
  5. 3idb: Crystal Structure of (108-268)riib:c Holoenzyme of Camp- Dependent Protein Kinase
  6. 3fjq: Crystal Structure of Camp-dependent Protein Kinase Catalytic Subunit Alpha in Complex with Peptide Inhibitor Pki Alpha (6-25)
  7. 3fhi: Crystal Structure of a Complex between The Catalytic and Regulatory (ri{alpha}) Subunits of Pka
  8. 3e8e: Crystal Structures of The Kinase Domain of Pka in Complex with Atp-competitive Inhibitors
  9. 3e8c: Crystal Structures of The Kinase Domain of Pka in Complex with Atp-competitive Inhibitors
  10. 3dne: Camp-dependent Protein Kinase Pka Catalytic Subunit with Pki-5-24
  11. 3dnd: Camp-dependent Protein Kinase Pka Catalytic Subunit with Pki-5-24
  12. 3bwj: Complex of Pka with The Bisubstrate Protein Kinase Inhibitor Lead Compound Arc-1034
  13. 3agm: Complex of Pka with The Bisubstrate Protein Kinase Inhibitor Arc-670
  14. 3agl: Complex of Pka with The Bisubstrate Protein Kinase Inhibitor Arc-1039
  15. 3ag9: Complex of Pka with The Bisubstrate Protein Kinase Inhibitor Arc-1012
  16. 2vo7: Structure of Pka Complexed with 4-(4-chlorobenzyl)-1-(7h- Pyrrolo(2,3-d)pyrimidin-4-yl)piperidin-4-ylamine
  17. 2vo6: Structure of Pka-pkb Chimera Complexed with 4-(4- Chlorobenzyl)-1-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)piperidin- 4-ylamine
  18. 2vo3: Structure of Pka-pkb Chimera Complexed with C-(4-(4- Chlorophenyl)-1-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)piperidin- 4-yl)methylamine
  19. 2vo0: Structure of Pka-pkb Chimera Complexed with C-(4-(4- Chlorophenyl)-1-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)piperidin- 4-yl)methylamine
  20. 2vny: Structure of Pka-pkb Chimera Complexed with (1-(9h-purin-6- Yl)piperidin-4-yl)amine
  21. 2vnw: Structure of Pka-pkb Chimera Complexed with (1-(9h-purin-6- Yl)piperidin-4-yl)methanamine
  22. 2uzw: Pka Structures of Indazole-pyridine Series of Akt Inhibitors
  23. 2uzv: Pka Structures of Indazole-pyridine Series of Akt Inhibitors
  24. 2uzu: Pka Structures of Indazole-pyridine Series of Akt Inhibitors
  25. 2uzt: Pka Structures of Akt, Indazole-pyridine Inhibitors
  26. 2uw8: Structure of Pka-pkb Chimera Complexed with 2-(4-chloro- Phenyl)-2-phenyl-ethylamine
  27. 2uw5: Structure of Pka-pkb Chimera Complexed with (r)-2-(4- Chloro-phenyl)-2-(4-1h-pyrazol-4-yl)-phenyl)-ethylamine
  28. 2uw4: Structure of Pka-pkb Chimera Complexed with 2-(4-(5-methyl- 1h-pyrazol-4-yl)-phenyl)-ethylamine
  29. 2uw3: Structure of Pka-pkb Chimera Complexed with 5-methyl-4- Phenyl-1h-pyrazole
  30. 2qvs: Crystal Structure of Type Iia Holoenzyme of Camp-dependent Protein Kinase
  31. 2qur: Crystal Structure of F327A/K285P Mutant of Camp-dependent Protein Kinase
  32. 2qcs: A Complex Structure between The Catalytic and Regulatory Subunit of Protein Kinase a That Represents The Inhibited State
  33. 2ojf: Crystal Structure of Protein Kinase a in Complex with Pyridine-pyrazolopyridine Based Inhibitors
  34. 2oh0: Crystal Structure of Protein Kinase a in Complex with Pyridine-pyrazolopyridine Based Inhibitors
  35. 2gnf: Protein Kinase a Fivefold Mutant Model of Rho-kinase with Y- 27632
  36. 2gng: Protein Kinase a Fivefold Mutant Model of Rho-kinase
  37. 2gnh: Pka Five Fold Mutant Model of Rho-kinase with H1152P
  38. 2gni: Pka Fivefold Mutant Model of Rho-kinase with Inhibitor Fasudil (ha1077)
  39. 2gnj: Pka Three Fold Mutant Model of Rho-kinase with Y-27632
  40. 2gnl: Pka Threefold Mutant Model of Rho-kinase with Inhibitor H- 1152p
  41. 2hwn: Crystal Structure of Rii Alpha Dimerization/docking Domain of Pka Bound to The D-akap2 Peptide
  42. 2izx: Molecular Basis of Akap Specificity for Pka Regulatory Subunits
  43. 2izy: Molecular Basis of Akap Specificity for Pka Regulatory Subunits
  44. 2jds: Structure of Camp-dependent Protein Kinase Complexed with A- 443654
  45. 2jdt: Structure of Pka-pkb Chimera Complexed with Isoquinoline-5- Sulfonic Acid (2-(2-(4-chlorobenzyloxy) Ethylamino)ethyl) Amide
  46. 2jdv: Structure of Pka-pkb Chimera Complexed with A-443654
  47. 3kkv: Structure of Pka with a Protein Kinase B-selective Inhibitor.
  48. 3l9l: Crystal Structure of Pka with Compound 36
  49. 3l9m: Crystal Structure of Pkab3 (pka Triple Mutant V123A, L173M, Q181K) with Compound 18
  50. 3l9n: Crystal Structure of Pkab3 (pka Triple Mutant V123A, L173M, Q181K) with Compound 27
  51. 3pvb: Crystal Structure of (73-244)ria:c Holoenzyme of Camp-dependent Protein Kinase
  52. 3nx8: Human Camp Dependent Protein Kinase in Complex with Phenol
  53. 3ama: Protein Kinase a Sixfold Mutant Model of Aurora B with Inhibitor Jnj- 7706621
  54. 3amb: Protein Kinase a Sixfold Mutant Model of Aurora B with Inhibitor Vx- 680
  55. 3oog: Human Camp-dependent Protein Kinase in Complex with a Small Fragment
  56. 3ovv: Human Camp-dependent Protein Kinase in Complex with an Inhibitor
  57. 3owp: Human Camp-dependent Protein Kinase in Complex with an Inhibitor
  58. 3oxt: Human Camp-dependent Protein Kinase in Complex with an Inhibitor
  59. 3p0m: Human Camp-dependent Protein Kinase in Complex with an Inhibitor
  60. 3poo: Human Camp-dependent Protein Kinase in Complex with an Inhibitor
  61. 3qal: Crystal Structure of ARG280ALA Mutant of Catalytic Subunit of Camp- Dependent Protein Kinase
  62. 3qam: Crystal Structure of GLU208ALA Mutant of Catalytic Subunit of Camp- Dependent Protein Kinase
  63. 4dfy: Crystal Structure of R194A Mutant of Camp-dependent Protein Kinase with Unphosphorylated Activation Loop
  64. 4ae6: Structure and Function of The Human Sperm-specific Isoform of Protein Kinase a (pka) Catalytic Subunit Calpha 2
  65. 4ae9: Structure and Function of The Human Sperm-specific Isoform of Protein Kinase a (pka) Catalytic Subunit C Alpha 2
  66. 4dfx: Crystal Structure of Myristoylated K7C Catalytic Subunit of Camp- Dependent Protein Kinase in Complex with Sp20 and Amp-pnp
  67. 4dfz: Crystal Structure of Myristoylated K7C Catalytic Subunit of Camp- Dependent Protein Kinase in Complex with Sp20
  68. 4dg0: Crystal Structure of Myristoylated Wt Catalytic Subunit of Camp- Dependent Protein Kinase in Complex with Sp20 and Amp-pnp
  69. 4dg2: Crystal Structure of Myristoylated Wt Catalytic Subunit of Camp- Dependent Protein Kinase in Complex with Sp20
  70. 4dh1: Low Temperature X-ray Structure of Camp Dependent Protein Kinase a Catalytic Subunit with Low Mg2+, Atp and Ip20
  71. 4dh3: Low Temperature X-ray Structure of Camp Dependent Protein Kinase a Catalytic Subunit with High Mg2+, Atp and Ip20
  72. 4dh5: Room Temperature X-ray Structure of Camp Dependent Protein Kinase a Catalytic Subunit with High Mg2+, Adp, Phosphate, and Ip20
  73. 4dh7: Low Temperature X-ray Structure of Camp Dependent Protein Kinase a Catalytic Subunit with High Mg2+, Amp-pnp and Ip20'
  74. 4dh8: Room Temperature X-ray Structure of Camp Dependent Protein Kinase a Catalytic Subunit with High Mg2+, Amp-pnp and Ip20
  75. 4din: Novel Localization and Quaternary Structure of The Pka Ri Beta Holoenzyme
  76. 4axa: Structure of Pka-pkb Chimera Complexed with (1s)-2-amino-1-( 4-chlorophenyl)-1-(4-(1h-pyrazol-4-yl)phenyl)ethan-1-ol
  77. 3vqh: Bromine Sad Partially Resolves Multiple Binding Modes for Pka Inhibitor H-89
  78. 4dg3: Crystal Structure of R336A Mutant of Camp-dependent Protein Kinase with Unphosphorylated Turn Motif.
  79. 3zo1: The Synthesis and Evaluation of Diazaspirocyclic Protein Kinase Inhibitors
  80. 3zo2: The Synthesis and Evaluation of Diazaspirocyclic Protein Kinase Inhibitors
  81. 3zo3: The Synthesis and Evaluation of Diazaspirocyclic Protein Kinase Inhibitors
  82. 3zo4: The Synthesis and Evaluation of Diazaspirocyclic Protein Kinase Inhibitors
  83. 4hpt: Crystal Structure of The Catalytic Subunit of Camp-dependent Protein Kinase Displaying Complete Phosphoryl Transfer of Amp-pnp onto a Substrate Peptide
  84. 4hpu: Crystal Structure of The Catalytic Subunit of Camp-dependent Protein Kinase Displaying Partial Phosphoryl Transfer of Amp-pnp onto a Substrate Peptide
  85. 4ie9: Bovine Pka C-alpha in Complex with 3-pyridylmethyl-5-methyl-1h- Pyrazole-3-carboxylate
  86. 4ij9: Bovine Pka C-alpha in Complex with 2-[[5-(4-pyridyl)-1h-1,2,4-triazol- 3-yl]sulfanyl]-1-(2-thiophenyl)ethanone
  87. 4iac: X-ray Structure of Camp Dependent Protein Kinase a in Compelx with High Mg2+ Concentration, Amp-pcp and Pseudo-substrate Peptide Sp20
  88. 4iad: Low Temperature X-ray Structure of Camp Dependent Protein Kinase a in Compelx with High Mg2+ Concentration, Adp and Phosphorylated Peptide Psp20
  89. 4iaf: Room Temperature X-ray Structure of Camp Dependent Protein Kinase a in Complex with High Mg2+ Concentration, Adp and Phosphorylated Peptide Psp20
  90. 4iai: X-ray Structure of Camp Dependent Protein Kinase a in Complex with High Ca2+ Concentration, Adp and Phosphorylated Peptide Psp20
  91. 4iak: Low Temperature X-ray Structure of Camp Dependent Protein Kinase a in Complex with High Sr2+ Concentration, Adp and Phosphorylated Peptide Psp20
  92. 4iay: Room Temperature X-ray Structure of Camp Dependent Protein Kinase a in Complex with High Sr2+ Concentration, Adp and Phosphorylated Peptide Psp20
  93. 4iaz: Structure of Camp Dependent Protein Kinase a in Complex with High Ba2+ Concentration, Adp and Phosphorylated Peptide Psp20
  94. 3j4q: Pseudo-atomic Model of The Akap18-pka Complex in a Bent Conformation Derived from Electron Microscopy
  95. 3j4r: Pseudo-atomic Model of The Akap18-pka Complex in a Linear Conformation Derived from Electron Microscopy
  96. 4c33: PKA-S6K1 Chimera Apo
  97. 4c34: PKA-S6K1 Chimera with Staurosporine Bound
  98. 4c35: PKA-S6K1 Chimera with Compound 1 (nu1085) Bound
  99. 4c36: PKA-S6K1 Chimera with Compound 15e (cct147581) Bound
  100. 4c37: PKA-S6K1 Chimera with Compound 21a (cct196539) Bound
  101. 4c38: PKA-S6K1 Chimera with Compound 21e (cct239066) Bound
  102. 4ib0: X-ray Structure of Camp Dependent Protein Kinase a in Complex with High Na+ Concentration, Adp and Phosphorylated Peptide Psp20
  103. 4ib1: Structure of Camp Dependent Protein Kinase a in Complex with High K+ Concentration, Adp and Phosphorylated Peptide Psp20
  104. 4ib3: Structure of Camp Dependent Protein Kinase a in Complex with Adp, Phosphorylated Peptide Psp20, and No Metal
  105. 4nts: Apo Structure of The Catalytic Subunit of Camp-dependent Protein Kinase
  106. 4ntt: Structure of The Catalytic Subunit of Camp-dependent Protein Kinase Bound to Adp and One Magnesium Ion
  107. 4o21: Product Complex of Metal-free Pkac, Atp-gamma-s and Sp20.
  108. 4o22: Binary Complex of Metal-free Pkac with Sp20.
  109. 4wih: Crystal Structure of Camp-dependent Protein Kinase a from Cricetulus Griseus
  110. 4wb5: Crystal Structure of Human Camp-dependent Protein Kinase a (catalytic Alpha Subunit)
  111. 4wb6: Crystal Structure of a L205R Mutant of Human Camp-dependent Protein Kinase a (catalytic Alpha Subunit)
  112. 4wb7: Crystal Structure of a Chimeric Fusion of Human Dnaj (hsp40) and Camp- Dependent Protein Kinase a (catalytic Alpha Subunit)
  113. 4wb8: Crystal Structure of Human Camp-dependent Protein Kinase a (catalytic Alpha Subunit), Exon 1 Deletion
  114. 4wbb: Single Turnover Autophosphorylation Cycle of The Pka Riib Holoenzyme
  115. 4xw4: X-ray Structure of Pkac with Amppnp, Sp20, Calcium Ions
  116. 4xw5: X-ray Structure of Pkac with Atp, Cp20, Calcium Ions
  117. 4xw6: X-ray Structure of Pkac with Adp, Free Phosphate Ion, Cp20, Magnesium Ions
  118. 4yxr: Crystal Structure of Pka in Complex with Inhibitor.
  119. 4yxs: Camp-dependent Protein Kinase Pka Catalytic Subunit with Pki-5-24
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