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enzyme (lysozyme)

 
Enzymes
  Enzyme classes:
  EC 1: Oxidoreductases
  EC 2: Transferases
    EC 2.1
    EC 2.2
    EC 2.3
    EC 2.4
    EC 2.5
    EC 2.6
    EC 2.7
      EC 2.7.1
      EC 2.7.2
      EC 2.7.3
      EC 2.7.4
      EC 2.7.5
      EC 2.7.6
      EC 2.7.7
      EC 2.7.8
      EC 2.7.9
      EC 2.7.10
      EC 2.7.11
        EC 2.7.11.1
        EC 2.7.11.2
        EC 2.7.11.3
        EC 2.7.11.4
        EC 2.7.11.6
        EC 2.7.11.7
        EC 2.7.11.8
        EC 2.7.11.9
        EC 2.7.11.10
        EC 2.7.11.11
        EC 2.7.11.12
        EC 2.7.11.13
        EC 2.7.11.14
        EC 2.7.11.15
        EC 2.7.11.16
        EC 2.7.11.17
        EC 2.7.11.18
        EC 2.7.11.19
        EC 2.7.11.20
        EC 2.7.11.21
        EC 2.7.11.22
        EC 2.7.11.23
        EC 2.7.11.24
        EC 2.7.11.25
        EC 2.7.11.26
        EC 2.7.11.27
        EC 2.7.11.28
        EC 2.7.11.29
        EC 2.7.11.30
        EC 2.7.11.31
      EC 2.7.12
      EC 2.7.13
      EC 2.7.14
    EC 2.8
    EC 2.9
  EC 3: Hydrolases
  EC 4: Lyases
  EC 5: Isomerases
  EC 6: Ligases
  General information:
  Catalytic mechanism
  Enzyme kinetics
  Inhibitors
  Enzymes in industry

EC 2.7.11.24 - ATP:protein phosphotransferase (MAPKK- activated) (mitogen- activated protein kinase)



3D structures of EC 2.7.11.24 - mitogen-activated protein kinase in Protein Data Bank

updated: 29 May 2015, 1:12

In total: 319 PDB structures of EC 2.7.11.24 - mitogen-activated protein kinase:
  1. 3ocg: P38 Alpha Kinase Complexed with a 5-amino-pyrazole Based Inhibitor
  2. 3oc1: Conformational Plasticity of P38 Map Kinase Dfg Motif Mutants in Response to Inhibitor Binding
  3. 3obj: Conformational Plasticity of P38 Map Kinase Dfg Mutants in Response to Inhibitor Binding
  4. 3obg: Conformational Plasticity of P38 Map Kinase Dfg Mutants in Response to Inhibitor Binding
  5. 3o8u: Conformational Plasticity of P38 Map Kinase Dfg Motif Mutants in Response to Inhibitor Binding
  6. 3o8t: Conformational Plasticity of P38 Map Kinase Dfg-motif Mutants in Response to Inhibitor Binding
  7. 3o8p: Conformational Plasticity of P38 Map Kinase Dfg Motif Mutants in Response to Inhibitor Binding
  8. 3nww: P38 Alpha Kinase Complexed with a 2-aminothiazol-5-yl-pyrimidine Based Inhibitor
  9. 3npc: Crystal Structure of Jnk2 Complexed with Birb796
  10. 3nnx: Crystal Structure of Phosphorylated P38 Alpha in Complex with Dp802
  11. 3nnw: Crystal Structure of P38 Alpha in Complex with Dp802
  12. 3nnv: Crystal Structure of P38 Alpha in Complex with Dp437
  13. 3nnu: Crystal Structure of P38 Alpha in Complex with Dp1376
  14. 3new: P38-alpha Complexed with Compound 10
  15. 3mvm: P38 Alpha Map Kinase Complexed with Pyrrolotriazine Inhibitor 7v
  16. 3mvl: P38 Alpha Map Kinase Complexed with Pyrrolotriazine Inhibitor 7k
  17. 3mpt: Crystal Structure of P38 Kinase in Complex with a Pyrrole-2- Carboxamide Inhibitor
  18. 3mpa: Conformational Plasticity of P38 Map Kinase Dfg Motif Mutants in Response to Inhibitor Binding
  19. 3mh3: Mutagenesis of P38 Map Kinase Establishes Key Roles of Phe169 in Function and Structural Dynamics and Reveals a Novel Dfg-out State
  20. 3mh2: Mutagenesis of P38 Map Kinase Establishes Key Roles of Phe169 in Function and Structural Dynamics and Reveals a Novel Dfg-out State
  21. 3mh1: Mutagenesis of P38 Map Kinase Establishes Key Roles of Phe169 in Function and Structural Dynamics and Reveals a Novel Dfg-out State
  22. 3mh0: Mutagenesis of P38 Map Kinase Eshtablishes Key Roles of Phe169 in Function and Structural Dynamics and Reveals a Novel Dfg-out State
  23. 3mgy: Mutagenesis of P38 Map Kinase Eshtablishes Key Roles of Phe169 in Function and Structural Dynamics and Reveals a Novel Dfg-out State
  24. 3lhj: Crystal Structure of P38A Mitogen-activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor.
  25. 3l8x: P38 Alpha Kinase Complexed with a Pyrazolo-pyrimidine Based Inhibitor
  26. 3l8s: Human P38 Map Kinase in Complex with Cp-547632
  27. 3kvx: Jnk3 Bound to Aminopyrimidine Inhibitor, Sr-3562
  28. 3kq7: Structure of Human P38ALPHA with N-[4-methyl-3-(6-{[2-(1- Methylpyrrolidin-2-yl)ethyl]amino}pyridine-3-amido)phenyl]- 2-(morpholin-4-yl)pyridine-4-carboxamide
  29. 3kf7: Crystal Structure of Human P38ALPHA Complexed with a Triazolopyrimidine Compound
  30. 3k3j: P38ALPHA Bound to Novel Dfg-out Compound Pf-00416121
  31. 3k3i: P38ALPHA Bound to Novel Dgf-out Compound Pf-00215955
  32. 3iw8: Structure of Inactive Human P38 Map Kinase in Complex with a Thiazole-urea
  33. 3iw7: Human P38 Map Kinase in Complex with an Imidazo-pyridine
  34. 3iw6: Human P38 Map Kinase in Complex with a Benzylpiperazin- Pyrrol
  35. 3iw5: Human P38 Map Kinase in Complex with an Indole Derivative
  36. 3itz: Crystal Structure of P38A Mitogen-activated Protein Kinase in Complex with a Pyrazolopyridazine Inhibitor
  37. 3iph: Crystal Structure of P38 in Complex with a Biphenylamide Inhibitor
  38. 1pmq: The Structure of Jnk3 in Complex with an Imidazole- Pyrimidine Inhibitor
  39. 3i60: Crystal Structure of Erk2 Bound to (s)-4-(2-(2- Chlorophenylamino)-5-methylpyrimidin-4-yl)-n-(2-hydroxy-1- Phenylethyl)-1h-pyrrole-2-carboxamide
  40. 3i5z: Crystal Structure of Erk2 Bound to (s)-n-(2-hydroxy-1- Phenylethyl)-4-(5-methyl-2-(phenylamino)pyrimidin-4-yl)-1h- Pyrrole-2-carboxamide
  41. 3hvc: Crystal Structure of Human P38ALPHA Map Kinase
  42. 3hv7: Human P38 Map Kinase in Complex with Rl38
  43. 3hv6: Human P38 Map Kinase in Complex with Rl39
  44. 3hv5: Human P38 Map Kinase in Complex with Rl24
  45. 3hv4: Human P38 Map Kinase in Complex with Rl51
  46. 3hv3: Human P38 Map Kinase in Complex with Rl49
  47. 3huc: Human P38 Map Kinase in Complex with Rl40
  48. 3hub: Human P38 Map Kinase in Complex with Scios-469
  49. 3hrb: P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor
  50. 3hp5: Crystal Structure of Human P38ALPHA Complexed with a Pyrimidopyridazinone Compound
  51. 3hp2: Crystal Structure of Human P38ALPHA Complexed with a Pyridinone Compound
  52. 3hll: Crystal Structure of Human P38ALPHA Complexed with Ph-797804
  53. 3hl7: Crystal Structure of Human P38ALPHA Complexed with Sd-0006
  54. 3heg: P38 in Complex with Sorafenib
  55. 3hec: P38 in Complex with Imatinib
  56. 3ha8: The Complex Structure of The Map Kinase P38/compound 14b
  57. 3gp0: Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 Beta) in Complex with Nilotinib
  58. 3gi3: Crystal Structure of a N-phenyl-n'-naphthylurea Analog in Complex with P38 Map Kinase
  59. 3gfe: Crystal Structure of P38A Mitogen-activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor
  60. 3gcv: Human P38 Map Kinase in Complex with Rl62
  61. 3gcu: Human P38 Map Kinase in Complex with Rl48
  62. 3gcs: Human P38 Map Kinase in Complex with Sorafenib
  63. 3gcq: Human P38 Map Kinase in Complex with Rl45
  64. 3gcp: Human P38 Map Kinase in Complex with Sb203580
  65. 3gc9: The Structure of P38BETA C119S, C162S in Complex with a Dihydroquinazolinone Inhibitor
  66. 3gc8: The Structure of P38BETA C162S in Complex with a Dihydroquinazolinone
  67. 3gc7: The Structure of P38ALPHA in Complex with a Dihydroquinazolinone
  68. 3g9n: Jnk3 Bound to (z)-1-((6-fluoro-4h-benzo[d][1,3]dioxin-8-yl) Methyl)-3-(hydroxyimino)-4-phenylindolin-2-one
  69. 3g9l: Jnk3 Bound to (z)-1-((6-fluoro-4h-benzo[d][1,3]dioxin-8-yl) Methyl)-3-(hydroxyimino)-4-styrylindolin-2-one
  70. 3g90: Jnk-3 Bound to (z)-5-fluoro-1-((6-fluoro-4h-benzo[d][1, 3]dioxin-8-yl)methyl)-3-(hydroxyimino)indolin-2-one
  71. 3fv8: Jnk3 Bound to Piperazine Amide Inhibitor, Sr2774.
  72. 3fsk: P38 Kinase Crystal Structure in Complex with Ro6257
  73. 3fsf: P38 Kinase Crystal Structure in Complex with 3-(2,6- Dichloro-phenyl)-7-[4-(2-diethylamino-ethoxy)-phenylamino]- 1-methyl-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one
  74. 3fmn: P38 Kinase Crystal Structure in Complex with Ro2530
  75. 3fmm: P38 Kinase Crystal Structure in Complex with Ro6226
  76. 3fml: P38 Kinase Crystal Structure in Complex with Ro6224
  77. 3fmk: P38 Kinase Crystal Structure in Complex with 6-(2,4- Difluoro-phenoxy)-8-methyl-2-((s)-1-methyl-2-tetrazol-2-yl- Ethylamino)-8h-pyrido[2,3-d]pyrimidin-7-one
  78. 3fmj: P38 Kinase Crystal Structure in Complex with 4-(5-methyl-3- Phenyl-isoxazol-4-yl)-pyrimidin-2-ylamine
  79. 3fmh: P38 Kinase Crystal Structure in Complex with 6-(2,4- Difluoro-phenoxy)-8-methyl-2-((r)-1-methyl-2-tetrazol-2-yl- Ethylamino)-8h-pyrido[2,3-d]pyrimidin-7-one
  80. 3flz: P38 Kinase Crystal Structure in Complex with 8-methyl-6- Phenoxy-2-(tetrahydro-pyran-4-ylamino)-8h-pyrido[2,3- D]pyrimidin-7-one
  81. 3fly: P38 Kinase Crystal Structure in Complex with 6-(2,4- Difluoro-phenoxy)-2-isopropylamino-8-methyl-8h-pyrido[2,3- D]pyrimidin-7-one
  82. 3flw: P38 Kinase Crystal Structure in Complex with Pamapimod
  83. 3fls: P38 Kinase Crystal Structure in Complex with 6-(2,4- Difluoro-phenoxy)-2-((r)-2-methanesulfonyl-1-methyl- Ethylamino)-8-methyl-8h-pyrido[2,3-d]pyrimidin-7-one
  84. 3flq: P38 Kinase Crystal Structure in Complex with 6-(2,4- Difluoro-phenoxy)-2-((s)-2-methanesulfonyl-1-methyl- Ethylamino)-8-methyl-8h-pyrido[2,3-d]pyrimidin
  85. 3fln: P38 Kinase Crystal Structure in Complex with R1487
  86. 3fl4: P38 Kinase Crystal Structure in Complex with Ro5634
  87. 3fko: P38 Kinase Crystal Structure in Complex with Ro3668
  88. 3fkn: P38 Kinase Crystal Structure in Complex with Ro7125
  89. 3fkl: P38 Kinase Crystal Structure in Complex with Ro9552
  90. 3fi4: P38 Kinase Crystal Structure in Complex with Ro4499
  91. 3fi3: Crystal Structure of Jnk3 with Indazole Inhibitor, Sr-3737
  92. 3fi2: Crystal Structure of Jnk3 with Amino-pyrazole Inhibitor, Sr- 3451
  93. 3fc1: Crystal Structure of P38 Kinase Bound to Pyrimido- Pyridazinone Inhibitor
  94. 3elj: Jnk1 Complexed with a Bis-anilino-pyrrolopyrimidine Inhibitor.
  95. 3e93: Crystal Structure of P38 Kinase in Complex with a Biaryl Amide Inhibitor
  96. 3e92: Crystal Structure of P38 Kinase in Complex with a Biaryl Amide Inhibitor
  97. 3e7o: Crystal Structure of Jnk2
  98. 3dt1: P38 Complexed with a Quinazoline Inhibitor
  99. 3ds6: P38 Complex with a Phthalazine Inhibitor
  100. 3da6: Crystal Structure of Human Jnk3 Complexed with N-(3-methyl- 4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy) Naphthalen-1-yl)-1h-benzo[d]imidazol-2-amine
  101. 3d83: Crystal Structure of P38 Kinase in Complex with a Biphenyl Amide Inhibitor
  102. 3d7z: Crystal Structure of P38 Kinase in Complex with a Biphenyl Amide Inhibitor
  103. 3ctq: Structure of Map Kinase P38 in Complex with a 1-o-tolyl-1,2, 3-triazole-4-carboxamide
  104. 3coi: Crystal Structure of P38DELTA Kinase
  105. 3cgo: Irak-4 Inhibitors (part Ii)- a Structure Based Assessment of Imidazo[1,2 A]pyridine Binding
  106. 3cgf: Irak-4 Inhibitors (part Ii)- a Structure Based Assessment of Imidazo[1,2 A]pyridine Binding
  107. 3c9w: Crystal Structure of Erk-2 with Hypothemycin Covalently Bound
  108. 3c5u: P38 Alpha Map Kinase Complexed with a Benzothiazole Based Inhibitor
  109. 3bx5: P38 Alpha Map Kinase Complexed with Bms-640994
  110. 3bv3: Morpholino Pyrrolotriazine P38 Alpha Map Kinase Inhibitor Compound 2
  111. 3bv2: Morpholino Pyrrolotriazine P38 Alpha Map Kinase Inhibitor Compound 30
  112. 2zoq: Structural Dissection of Human Mitogen-activated Kinase Erk1
  113. 2zdu: Crystal Structure of Human Jnk3 Complexed with an Isoquinolone Inhibitor
  114. 2zdt: Crystal Structure of Human Jnk3 Complexed with an Isoquinolone Inhibitor
  115. 2zb1: Crystal Structure of P38 in Complex with Biphenyl Amide Inhibitor
  116. 2zb0: Crystal Structure of P38 in Complex with Biphenyl Amide Inhibitor
  117. 2zaz: Crystal Structure of P38 in Complex with 4-anilino Quinoline Inhibitor
  118. 2z7l: Unphosphorylated Mitogen Activated Protein Kinase Erk2 in Complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin 2-yl]amino}phenyl)acetic Acid
  119. 2waj: Crystal Structure of Human Jnk3 Complexed with a 1-aryl-3,4- Dihydroisoquinoline Inhibitor
  120. 2rg6: Phenylalanine Pyrrolotriazine P38 Alpha Map Kinase Inhibitor Compound 11j
  121. 2rg5: Phenylalanine Pyrrolotriazine P38 Alpha Map Kinase Inhibitor Compound 11b
  122. 2r9s: C-jun N-terminal Kinase 3 with 3,5-disubstituted Quinoline Inhibitor
  123. 2qd9: P38 Alpha Map Kinase Inhibitor Based on Heterobicyclic Scaffolds
  124. 2q8y: Structural Insight into The Enzymatic Mechanism of The Phophothreonine Lyase
  125. 2puu: Crystal Structure of P38 Complex with 1-(5-tert-butyl-2-p- Tolyl-2h-pyrazol-3-yl)-3-[4-(6-morpholin-4-ylmethyl- Pyridin-3-yl)naphthalen-1-yl]urea
  126. 2p33: Synthesis and Sar of Aminopyrimidines as Novel C-jun N- Terminal Kinase (jnk) Inhibitors
  127. 2oza: Structure of P38ALPHA Complex
  128. 2onl: Crystal Structure of The P38A-MAPKAP Kinase 2 Heterodimer
  129. 2okr: Crystal Structure of The P38A-MAPKAP Kinase 2 Heterodimer
  130. 2ok1: Crystal Structure of Jnk3 Bound to N-benzyl-4-(4-(3- Chlorophenyl)-1h-pyrazol-3-yl)-1h-pyrrole-2-carboxamide
  131. 2ojj: Crystal Structure of Erk2 in Complex with (s)-n-(1-(3- Chloro-4-fluorophenyl)-2-hydroxyethyl)-4-(4-(3- Chlorophenyl)-1h-pyrazol-3-yl)-1h-pyrrole-2-carboxamide
  132. 2oji: Crystal Structure of Erk2 in Complex with N-benzyl-4-(4-(3- Chlorophenyl)-1h-pyrazol-3-yl)-1h-pyrrole-2-carboxamide
  133. 2ojg: Crystal Structure of Erk2 in Complex with N,n-dimethyl-4-(4- Phenyl-1h-pyrazol-3-yl)-1h-pyrrole-2-carboxamide
  134. 2o2u: Crystal Structure of Human Jnk3 Complexed with N-(3-cyano-4, 5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide
  135. 2e14: The Structure of Erk2 in Complex with Fr148083
  136. 2o0u: Crystal Structure of Human Jnk3 Complexed with N-{3-cyano-6- [3-(1-piperidinyl)propanoyl]-4,5,6,7-tetrahydrothieno[2,3- C]pyridin-2-yl}-1-naphthalenecarboxamide
  137. 2npq: A Novel Lipid Binding Site in The P38 Alpha Map Kinase
  138. 2no3: Novel 4-anilinopyrimidines as Potent Jnk1 Inhibitors
  139. 2gmx: Selective Aminopyridine-based C-jun N-terminal Kinase Inhibitors with Cellular Activity
  140. 2gph: Docking Motif Interactions in The Map Kinase Erk2
  141. 2gtm: Mutated Mouse P38 Map Kinase Domain in Complex with Inhibitor Pg-892579
  142. 2gtn: Mutated Map Kinase P38 (mus Musculus) in Complex with Inhbitor Pg-951717
  143. 2h96: Discovery of Potent, Highly Selective, and Orally Bioavailable Pyridine Carboxamide C-jun Nh2-terminal Kinase Inhibitors
  144. 2i0h: The Structure of P38ALPHA in Complex with an Arylpyridazinone
  145. 2i6l: Crystal Structure of Human Mitogen Activated Protein Kinase 6 (mapk6)
  146. 3o17: Crystal Structure of Jnk1-alpha1 Isoform
  147. 3o2m: Crystal Structure of Jnk1-alpha1 Isoform Complex with a Biaryl Tetrazol (a-82118)
  148. 3od6: Crystal Structure of P38ALPHA Y323T Active Mutant
  149. 3ody: Crystal Structure of P38ALPHA Y323Q Active Mutant
  150. 3odz: Crystal Structure of P38ALPHA Y323R Active Mutant
  151. 3oef: Crystal Structure of Y323F Inactive Mutant of P38ALPHA Map Kinase
  152. 3p4k: The Third Conformation of P38A Map Kinase Observed in Phosphorylated P38A and in Solution
  153. 3ptg: Design and Synthesis of a Novel, Orally Efficacious Tri-substituted Thiophene Based Jnk Inhibitor
  154. 3lfa: Human P38 Map Kinase in Complex with Dasatinib
  155. 3lfb: Human P38 Map Kinase in Complex with Rl98
  156. 3lfc: Human P38 Map Kinase in Complex with Rl99
  157. 3lfd: Human P38 Map Kinase in Complex with Rl113
  158. 3lfe: Human P38 Map Kinase in Complex with Rl116
  159. 3lff: Human P38 Map Kinase in Complex with Rl166
  160. 3mw1: P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor
  161. 3py3: Crystal Structure of Phosphorylated P38ALPHA Map Kinase
  162. 3oxi: Design and Synthesis of Disubstituted Thiophene and Thiazole Based Inhibitors of Jnk for The Treatment of Neurodegenerative Diseases
  163. 3o71: Crystal Structure of Erk2/dcc Peptide Complex
  164. 3roc: Crystal Structure of Human P38 Alpha Complexed with a Pyrimidinone Compound
  165. 3rp9: Crystal Structure of The Apo Mapk from Toxoplasma Gondii, 25.m01780 or Tgme49_007820
  166. 3oy1: Highly Selective C-jun N-terminal Kinase (jnk) 2 and 3 Inhibitors with in Vitro Cns-like Pharmacokinetic Properties
  167. 3r63: Structure of Erk2 (spe) Mutant (S246E)
  168. 3qyw: Crystal Structure of Erk2 in Complex with an Inhibitor
  169. 3qyz: Crystal Structure of Erk2 in Complex with an Inhibitor
  170. 2xrw: Linear Binding Motifs for Jnk and for Calcineurin Antagonistically Control The Nuclear Shuttling of Nfat4
  171. 2xs0: Linear Binding Motifs for Jnk and for Calcineurin Antagonistically Control The Nuclear Shuttling of Nfat4
  172. 3p78: P38 Inhibitor-bound
  173. 3p79: P38 Inhibitor-bound
  174. 3p7a: P38 Inhibitor-bound
  175. 3p7b: P38 Inhibitor-bound
  176. 3p7c: P38 Inhibitor-bound
  177. 3p5k: P38 Inhibitor-bound
  178. 3pg3: Human P38 Map Kinase in Complex with Rl182
  179. 2yis: Triazolopyridine Inhibitors of P38 Kinase.
  180. 2yiw: Triazolopyridine Inhibitors of P38 Kinase
  181. 2yix: Triazolopyridine Inhibitors of P38
  182. 3pze: Jnk1 in Complex with Inhibitor
  183. 3sa0: Complex of Erk2 with Norathyriol
  184. 3zya: Human P38 Map Kinase in Complex with 2-amino-phenylamino- Dibenzosuberone
  185. 3que: Human P38 Map Kinase in Complex with Skepinone-l
  186. 3ttj: Crystal Structure of Jnk3 Complexed with Cc-359, a Jnk Inhibitor for The Prevention of Ischemia-reperfusion Injury
  187. 3s4q: P38 Alpha Kinase Complexed with a Pyrazolo-triazine Based Inhibitor
  188. 3tti: Crystal Structure of Jnk3 Complexed with Cc-930, an Orally Active Anti-fibrotic Jnk Inhibitor
  189. 3v6r: Discovery of Potent and Selective Covalent Inhibitors of Jnk
  190. 3v6s: Discovery of Potent and Selective Covalent Inhibitors of Jnk
  191. 2y8o: Crystal Structure of Human P38ALPHA Complexed with a Mapk Docking Peptide
  192. 2y9q: Crystal Structure of Human Erk2 Complexed with a Mapk Docking Peptide
  193. 3rin: P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor
  194. 3tg1: Crystal Structure of P38ALPHA in Complex with a Mapk Docking Partner
  195. 3qud: Human P38 Map Kinase in Complex with 2-amino-phenylamino-benzophenone
  196. 3s3i: P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor
  197. 3qyi: Map Kinase Erk2 Complexed with 1,1-dioxo-2,3-dihydrothiophen-3-yl Benzenesulfonate
  198. 4a9y: P38ALPHA Map Kinase Bound to Cmpd 8
  199. 4aa0: P38ALPHA Map Kinase Bound to Cmpd 2
  200. 4aa4: P38ALPHA Map Kinase Bound to Cmpd 22
  201. 4aa5: P38ALPHA Map Kinase Bound to Cmpd 33
  202. 4aac: P38ALPHA Map Kinase Bound to Cmpd 29
  203. 3zsg: X-ray Structure of P38ALPHA Bound to Tak-715
  204. 3zsh: X-ray Structure of P38ALPHA Bound to Scio-469
  205. 3zsi: X-ray Structure of P38ALPHA Bound to Vx-745
  206. 3zs5: Structural Basis for Kinase Selectivity of Three Clinical P38ALPHA Inhibitors
  207. 3zu7: Crystal Structure of a Designed Selected Ankyrin Repeat Protein in Complex with The Map Kinase Erk2
  208. 3zuv: Crystal Structure of a Designed Selected Ankyrin Repeat Protein in Complex with The Phosphorylated Map Kinase Erk2
  209. 4ewq: Human P38 Alpha Mapk in Complex with a Pyridazine Based Inhibitor
  210. 2lgc: Joint Nmr and X-ray Refinement Reveals The Structure of a Novel Dibenzo[a,d]cycloheptenone Inhibitor/p38 Map Kinase Complex in Solution
  211. 3tei: Crystal Structure of Human Erk2 Complexed with a Mapk Docking Peptide
  212. 4fux: Crystal Structure of The Erk2 Complexed with E75
  213. 4fuy: Crystal Structure of The Erk2 Complexed with Ek2
  214. 4fv0: Crystal Structure of The Erk2 Complexed with Ek3
  215. 4fv1: Crystal Structure of The Erk2 Complexed with Ek4
  216. 3u8w: Crystal Structure of P38A Mitogen-activated Protein Kinase in Complex with a Triazolopyridazinone Inhibitor
  217. 4b99: Crystal Structure of Mapk7 (erk5) with Inhibitor
  218. 4fv2: Crystal Structure of The Erk2 Complexed with Ek5
  219. 4fv3: Crystal Structure of The Erk2 Complexed with Ek6
  220. 4fv4: Crystal Structure of The Erk2 Complexed with Ek7
  221. 4fv5: Crystal Structure of The Erk2 Complexed with Ek9
  222. 4fv6: Crystal Structure of The Erk2 Complexed with E57
  223. 4fv7: Crystal Structure of The Erk2 Complexed with E94
  224. 4fv8: Crystal Structure of The Erk2 Complexed with E63
  225. 4fv9: Crystal Structure of The Erk2 Complexed with E71
  226. 4g6n: Crystal Structure of The Erk2
  227. 4g6o: Crystal Structure of The Erk2
  228. 4gsb: Monoclinic Crystal Form of The Apo-erk2
  229. 4gt3: Atp-bound Form of The Erk2 Kinase
  230. 4gva: Adp-bound Form of The Erk2 Kinase
  231. 4e5a: The W197A Mutant of P38A Map Kinase
  232. 4e5b: Structure of P38A Map Kinase without Bog
  233. 4e6a: P38A-PIA23 Complex
  234. 4e6c: P38A-PERIFOSINE Complex
  235. 4e8a: The Crystal Structure of P38A Map Kinase in Complex with Pia24
  236. 4fmq: Crystal Structure of Human Erk2 Complexed with a Mapk Docking Peptide
  237. 3uvp: Human P38 Map Kinase in Complex with Km048
  238. 3uvq: Human P38 Map Kinase in Complex with Fs218
  239. 3v3v: Structural and Functional Analysis of Quercetagetin, a Natural Jnk1 Inhibitor
  240. 4eh2: Human P38 Map Kinase in Complex with Np-f1 and Rl87
  241. 4eh3: Human P38 Map Kinase in Complex with Np-f2 and Rl87
  242. 4eh4: Human P38 Map Kinase in Complex with Np-f3 and Rl87
  243. 4eh5: Human P38 Map Kinase in Complex with Np-f4 and Rl87
  244. 4eh6: Human P38 Map Kinase in Complex with Np-f5 and Rl87
  245. 4eh7: Human P38 Map Kinase in Complex with Np-f6 and Rl87
  246. 4eh8: Human P38 Map Kinase in Complex with Np-f7 and Rl87
  247. 4eh9: Human P38 Map Kinase in Complex with Np-f11 and Rl87
  248. 4ehv: Human P38 Map Kinase in Complex with Np-f10 and Rl87
  249. 4h36: Crystal Structure of Jnk3 in Complex with Atf2 Peptide
  250. 4h39: Crystal Structure of Jnk3 in Complex with Jip1 Peptide
  251. 4h3b: Crystal Structure of Jnk3 in Complex with Sab Peptide
  252. 3uvr: Human P38 Map Kinase in Complex with Km064
  253. 3vud: Crystal Structure of a Cysteine-deficient Mutant M1 in Map Kinase Jnk1
  254. 3vug: Crystal Structure of a Cysteine-deficient Mutant M2 in Map Kinase Jnk1
  255. 3vuh: Crystal Structure of a Cysteine-deficient Mutant M3 in Map Kinase Jnk1
  256. 3vui: Crystal Structure of a Cysteine-deficient Mutant M2 in Map Kinase Jnk1
  257. 3vuk: Crystal Structure of a Cysteine-deficient Mutant M5 in Map Kinase Jnk1
  258. 3vul: Crystal Structure of a Cysteine-deficient Mutant M1 in Map Kinase Jnk1
  259. 3vum: Crystal Structure of a Cysteine-deficient Mutant M7 in Map Kinase Jnk1
  260. 3w55: The Structure of Erk2 in Complex with Fr148083
  261. 4dli: Human P38 Map Kinase in Complex with Rl87
  262. 4dlj: Human P38 Map Kinase in Complex with Rl163
  263. 4exu: Mapk13, Inactive Form
  264. 4eyj: Mapk13 Complex with Inhibitor
  265. 4eym: Mapk13 Complex with Inhibitor
  266. 4h3p: Crystal Structure of Human Erk2 Complexed with a Mapk Docking Peptide
  267. 4h3q: Crystal Structure of Human Erk2 Complexed with a Mapk Docking Peptide
  268. 4ic7: Crystal Structure of The Erk5 Kinase Domain in Complex with an Mkk5 Binding Fragment
  269. 4ic8: Crystal Structure of The Apo Erk5 Kinase Domain
  270. 4iz5: Structure of The Complex between Erk2 Phosphomimetic Mutant and Pea-15
  271. 4iz7: Structure of Non-phosphorylated Erk2 Bound to The Pea-15 Death Effector Domain
  272. 4iza: Structure of Dually Phosphorylated Erk2 Bound to The Pea-15 Death Effector Domain
  273. 3rtp: Design and Synthesis of Brain Penetrant Selective Jnk Inhibitors with Improved Pharmacokinetic Properties for The Prevention of Neurodegeneration
  274. 4awi: Human JNK1ALPHA Kinase with 4-phenyl-7-azaindole Ikk2 Inhibitor.
  275. 4e73: Crystal Structure of JNK1BETA-JIP in Complex with an Azaquinolone Inhbitor
  276. 4f9w: Human P38ALPHA Mapk in Complex with a Novel and Selective Small Molecule Inhibitor
  277. 4f9y: Human P38 Alpha Mapk in Complex with a Novel and Selective Small Molecule Inhibitor
  278. 4fa2: Human P38 Alpha Mitogen-activated Kinase in Complex with Sb239063
  279. 4geo: P38A Map Kinase Def-pocket Penta Mutant (M194A, L195A, H228A, I229A, Y258A)
  280. 4kin: Crystal Structure of Mitogen-activated Protein Kinase 14 (p38-h5) Complex with 5-(2-chlorophenyl)-n-(5-(cyclopropylcarbamoyl)-2- Methylphenyl)-2-thiophenecarboxamide
  281. 4kip: Crystal Structure of Mitogen-activated Protein Kinase 14 (p38-h5) Complex with 2-(2-chlorophenyl)-n-(5-(cyclopropylcarbamoyl)-2- Methylphenyl)-1,3-thiazole-5-carboxamide
  282. 4kiq: Crystal Structure of Mitogen-activated Protein Kinase 14 (p38-h5) Complex with Ethyl 6-((5-(cyclopropylcarbamoyl)-2-methylphenyl) Carbamoyl)-1h-indole-1-carboxylate
  283. 4ka3: Structure of Map Kinase in Complex with a Docking Peptide
  284. 4i5h: Crystal Structure of a Double Mutant Rat Erk2 Complexed with a Type II Quinazoline Inhibitor
  285. 4kke: The Crystal Structure of Amp-bound Jnk3
  286. 4kkg: Crystal Structure of Apo and Amp-bound Jnk3
  287. 4kkh: The Crystal Structure of Inhibitor-bound Jnk3
  288. 4l7f: Co-crystal Structure of Jnk1 and Ax13587
  289. 4l8m: Human P38 Map Kinase in Complex with a Dibenzoxepinone
  290. 4loo: Structural Basis of Autoactivation of P38 Alpha Induced by Tab1 (monoclinic Crystal Form)
  291. 4lop: Structural Basis of Autoactivation of P38 Alpha Induced by Tab1 (tetragonal Crystal Form)
  292. 4loq: Structural Basis of Autoactivation of P38 Alpha Induced by Tab1 (tetragonal Crystal Form with Bound Sulphate)
  293. 4m3a: Structural Determination of C-jun N-terminal Kinase from Drosophila Melanogaster
  294. 4n0s: Complex of Erk2 with Caffeic Acid
  295. 4n4s: A Double Mutant Rat Erk2 in Complex with a Pyrazolo[3,4-d]pyrimidine Inhibitor
  296. 4nif: Heterodimeric Structure of Erk2 and Rsk1
  297. 4o6e: Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine Inhibitors of Erk2
  298. 4qta: Structure of Human Erk2 in Complex with Sch772984 Revealing a Novel Inhibitor-induced Binding Pocket
  299. 4qtb: Structure of Human Erk1 in Complex with Sch772984 Revealing a Novel Inhibitor-induced Binding Pocket
  300. 4qtd: Structure of Human Jnk1 in Complex with Sch772984 and The Amppnp- Hydrolysed Triphosphate Revealing The Second Type-i Binding Mode
  301. 4qte: Structure of Erk2 in Complex with Vtx-11e, 4-{2-[(2-chloro-4- Fluorophenyl)amino]-5-methylpyrimidin-4-yl}-n-[(1s)-1-(3- Chlorophenyl)-2-hydroxyethyl]-1h-pyrrole-2-carboxamide
  302. 4qyy: Discovery of Novel, Dual Mechanism Erk Inhibitors by Affinity Selection Screening of an Inactive Kinase State
  303. 4u79: Crystal Structure of Human Jnk3 in Complex with a Benzenesulfonamide Inhibitor.
  304. 4whz: Design and Synthesis of Highly Potent and Isoform Selective Jnk3 Inhibitors: Sar Studies on Aminopyrazole Derivatives
  305. 4qum: Crystal Structure of Ptpn3 (ptph1) in Complex with a Dually Phosphorylated Mapk12 Peptide
  306. 4w4v: Jnk2/3 in Complex with 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1h- Pyrazol-1-yl)-n-(2-methylpyridin-4-yl)benzamide
  307. 4w4w: Jnk2/3 in Complex with N-(2-methylpyridin-4-yl)-3-{4- [(phenylcarbamoyl)amino]-1h-pyrazol-1-yl}benzamide
  308. 4w4x: Jnk2/3 in Complex with 3-(4-{[(4-fluorophenyl)carbamoyl]amino}-1h- Pyrazol-1-yl)-n-(2-methylpyridin-4-yl)benzamide
  309. 4w4y: Jnk2/3 in Complex with 3-(4-{[(4-methylphenyl)carbamoyl]amino}-1h- Pyrazol-1-yl)-n-(2-methylpyridin-4-yl)benzamide
  310. 4r3c: Crystal Structure of P38 Alpha Map Kinase in Complex with a Novel Isoform Selective Drug Candidate
  311. 4myg: Mapk13, Active Form
  312. 4ux9: Crystal Structure of Jnk1 Bound to a Mkk7 Docking Motif
  313. 4yno: Crystal Structure of Mapk13 at Inactive Form
  314. 4y46: Pyridopyrimidinone Derivatives as Potent and Selective C-jun N- Terminal Kinase (jnk) Inhibitors
  315. 4y5h: Pyridopyrimidinone Derivatives as Potent and Selective C-jun N- Terminal Kinase (jnk) Inhibitors
  316. 4z9l: The Structure of Jnk3 in Complex with an Imidazole-pyrimidine Inhibitor
  317. 4zzm: Human Erk2 in Complex with an Irreversible Inhibitor
  318. 4zzn: Human Erk2 in Complex with an Inhibitor
  319. 4zzo: Human Erk2 in Complex with an Irreversible Inhibitor
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