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enzyme (lysozyme)

 
Enzymes
  Enzyme classes:
  EC 1: Oxidoreductases
  EC 2: Transferases
    EC 2.1
    EC 2.2
    EC 2.3
    EC 2.4
    EC 2.5
    EC 2.6
    EC 2.7
      EC 2.7.1
      EC 2.7.2
      EC 2.7.3
      EC 2.7.4
      EC 2.7.5
      EC 2.7.6
      EC 2.7.7
      EC 2.7.8
      EC 2.7.9
      EC 2.7.10
      EC 2.7.11
        EC 2.7.11.1
        EC 2.7.11.2
        EC 2.7.11.3
        EC 2.7.11.4
        EC 2.7.11.6
        EC 2.7.11.7
        EC 2.7.11.8
        EC 2.7.11.9
        EC 2.7.11.10
        EC 2.7.11.11
        EC 2.7.11.12
        EC 2.7.11.13
        EC 2.7.11.14
        EC 2.7.11.15
        EC 2.7.11.16
        EC 2.7.11.17
        EC 2.7.11.18
        EC 2.7.11.19
        EC 2.7.11.20
        EC 2.7.11.21
        EC 2.7.11.22
        EC 2.7.11.23
        EC 2.7.11.24
        EC 2.7.11.25
        EC 2.7.11.26
        EC 2.7.11.27
        EC 2.7.11.28
        EC 2.7.11.29
        EC 2.7.11.30
        EC 2.7.11.31
      EC 2.7.12
      EC 2.7.13
      EC 2.7.14
    EC 2.8
    EC 2.9
  EC 3: Hydrolases
  EC 4: Lyases
  EC 5: Isomerases
  EC 6: Ligases
  General information:
  Catalytic mechanism
  Enzyme kinetics
  Inhibitors
  Enzymes in industry

EC 2.7.11.21 - ATP:protein phosphotransferase (spindle- pole- dependent) (polo kinase)



3D structures of EC 2.7.11.21 - polo kinase in Protein Data Bank

updated: 29 May 2015, 1:12

In total: 74 PDB structures of EC 2.7.11.21 - polo kinase:
  1. 3kb7: Crystal Structure of Polo-like Kinase 1 in Complex with a Pyrazoloquinazoline Inhibitor
  2. 3hik: Structure of Human Plk1-pbd in Complex with Plhspt
  3. 3hih: Structure of Human Plk1-pbd with Glycerol and Sulfate in The Phophopeptide Binding Site
  4. 3fvh: Polo-like Kinase 1 Polo Box Domain in Complex with Ac- Lhspta-nh2 Peptide
  5. 3fc2: Plk1 in Complex with Bi6727
  6. 3dbf: Crystal Structure of an Activated (thr->asp) Polo-like Kinase 1 (plk1) Catalytic Domain in Complex with Compound 562
  7. 3dbe: Crystal Structure of an Activated (thr->asp) Polo-like Kinase 1 (plk1) Catalytic Domain in Complex with Compound 557
  8. 3dbd: Crystal Structure of an Activated (thr->asp) Polo-like Kinase 1 (plk1) Catalytic Domain in Complex with Compound 094
  9. 3dbc: Crystal Structure of an Activated (thr->asp) Polo-like Kinase 1 (plk1) Catalytic Domain in Complex with Compound 257
  10. 3db8: Crystal Structure of an Activated (thr->asp) Polo-like Kinase 1 (plk1) Catalytic Domain in Complex with Compound 041
  11. 3db6: Crystal Structure of an Activated (thr->asp) Polo-like Kinase 1 (plk1) Catalytic Domain in Complex with Compound 902
  12. 3d5x: Crystal Structure of an Activated (thr->asp) Polo-like Kinase 1 (plk1) Catalytic Domain in Complex with Wortmannin.
  13. 3d5w: Crystal Structure of a Phosphorylated Polo-like Kinase 1 (plk1) Catalytic Domain in Complex with Adp.
  14. 3d5v: Crystal Structure of an Activated (thr->asp) Polo-like Kinase 1 (plk1) Catalytic Domain.
  15. 3d5u: Crystal Structure of a Wildtype Polo-like Kinase 1 (plk1) Catalytic Domain.
  16. 3cok: Crystal Structure of Plk4 Kinase
  17. 3c5l: Polo-like Kinase 1 Polo Box Domain in Complex with Pphspt Peptide
  18. 3bzi: Molecular and Structural Basis of Polo-like Kinase 1 Substrate Recognition: Implications in Centrosomal Localization
  19. 2v5q: Crystal Structure of Wild-type Plk-1 Kinase Domain in Complex with a Selective Darpin
  20. 2rku: Structure of Plk1 in Complex with Bi2536
  21. 2owb: Structure of The Catalytic Domain of Human Polo-like Kinase 1
  22. 2ou7: Structure of The Catalytic Domain of Human Polo-like Kinase 1
  23. 2ojx: Molecular and Structural Basis of Polo-like Kinase 1 Substrate Recognition: Implications in Centrosomal Localization
  24. 2ogq: Molecular and Structural Basis of Plk1 Substrate Recognition: Implications in Centrosomal Localization
  25. 2yac: Crystal Structure of Polo-like Kinase 1 in Complex with Nms-p937
  26. 3mhn: Human Plk1-pbd in Complex with Poloxime ((e)-4-(hydroxyimino)-2- Isopropyl-5-methylcyclohexa-2,5-dienone)
  27. 3mhq: Human Plk1-pbd with a Glycerol Bound at The Phophopeptide Binding Site
  28. 3mq8: Human Plk1-pbd in Complex with Thymoquinone at The Phophopeptide Binding Site
  29. 3p2w: Unliganded Form of Polo-like Kinase I Polo-box Domain
  30. 3p2z: Polo-like Kinase I Polo-box Domain in Complex with Plhspta Phosphopeptide from Pbip1
  31. 3p34: Polo-like Kinase I Polo-box Domain in Complex with Mqsptpl Phosphopeptide
  32. 3p35: Polo-like Kinase I Polo-box Domain in Complex with Mqspspl Phosphopeptide
  33. 3p36: Polo-like Kinase I Polo-box Domain in Complex with Dpplhspta Phosphopeptide from Pbip1
  34. 3p37: Polo-like Kinase I Polo-box Domain in Complex with Fdpplhspta Phosphopeptide from Pbip1
  35. 3q1i: Polo-like Kinase I Polo-box Domain in Complex with Fmpppmspsm Phosphopeptide from Tcerg1
  36. 3rq7: Polo-like Kinase 1 Polo Box Domain in Complex with a C6H5(CH2)8- Derivatized Peptide Inhibitor
  37. 3thb: Structure of Plk1 Kinase Domain in Complex with a Benzolactam-derived Inhibitor
  38. 4a4l: Crystal Structure of Polo-like Kinase 1 in Complex with a 5-(2-amino-pyrimidin-4-yl)-1h-pyrrole Inhibitor
  39. 4a4o: Crystal Structure of Polo-like Kinase 1 in Complex with a 2- (2-amino-pyrimidin-4-yl)-1,5,6,7-tetrahydro-pyrrolopyridin- 4-one Inhibitor
  40. 4dfw: Oxime-based post Solid-phase Peptide Diversification: Identification of High Affinity Polo-like Kinase 1 (plk1) Polo-box Domain Binding Peptides
  41. 4e67: The Structure of The Polo-box Domain (pbd) of Polo-like Kinase 1 (plk1) in Complex with Hydrocinnamoyl-derivatized Plhspta Peptide
  42. 4e9c: The Structure of The Polo-box Domain (pbd) of Polo-like Kinase 1 (plk1) in Complex with Ldpplhspta Phosphopeptide
  43. 4e9d: The Structure of The Polo-box Domain (pbd) of Polo-like Kinase 1 (plk1) in Complex with 3-(1-benzothiophen-2-yl)propanoyl-derivatized Dpplhspta Peptide
  44. 4g7n: The Structure of The Plk4 Cryptic Polo Box Reveals Two Tandem Polo Boxes Required for Centriole Duplication
  45. 4h5x: Human Plk1-pbd with a Glycerol Bound at The Phophopeptide Binding Site
  46. 4h71: Human Plk1-pbd in Complex with Poloxime ((e)-4-(hydroxyimino)-2- Isopropyl-5-methylcyclohexa-2,5-dienone)
  47. 4hco: Human Plk1-pbd in Complex with Thymoquinone at The Phophopeptide Binding Site
  48. 4hab: Crystal Structure of Plk1 Polo-box Domain in Complex with Pl-49
  49. 4hy2: Crystal Structure of Plk1 Polo-box Domain in Complex with Pl-42
  50. 4j52: Crystal Structure of Plk1 in Complex with a Pyrimidodiazepinone Inhibitor
  51. 4j53: Crystal Structure of Plk1 in Complex with Tak-960
  52. 4j7b: Crystal Structure of Polo-like Kinase 1
  53. 4b6l: Discovery of Oral Polo-like Kinase (plk) Inhibitors with Enhanced Selectivity Profile Using Residue Targeted Drug Design
  54. 4i5m: Selective & Brain-permeable Polo-like Kinase-2 (plk-2) Inhibitors That Reduce -synuclein Phosphorylation in Rat Brain
  55. 4i5p: Selective & Brain-permeable Polo-like Kinase-2 (plk-2) Inhibitors That Reduce -synuclein Phosphorylation in Rat Brain
  56. 4i6b: Selective & Brain-permeable Polo-like Kinase-2 (plk-2) Inhibitors That Reduce -synuclein Phosphorylation in Rat Brain
  57. 4i6f: Selective & Brain-permeable Polo-like Kinase-2 (plk-2) Inhibitors That Reduce -synuclein Phosphorylation in Rat Brain
  58. 4i6h: Selective & Brain-permeable Polo-like Kinase-2 (plk-2) Inhibitors That Reduce Alpha-synuclein Phosphorylation in Rat Brain
  59. 4jxf: Crystal Structure of Plk4 Kinase with an Inhibitor: 400631 ((1r,2s)-2- {3-[(e)-2-{4-[(dimethylamino)methyl]phenyl}ethenyl]-2h-indazol-6-yl}- 5'-methoxyspiro[cyclopropane-1,3'-indol]-2'(1'h)-one)
  60. 4lkl: Crystal Structure of Plk1 Polo-box Domain in Complex with Pl-55
  61. 4lkm: Crystal Structure of Plk1 Polo-box Domain in Complex with Pl-74
  62. 4n7v: Crystal Structure of Human Plk4 Cryptic Polo Box (cpb) in Complex with a Cep152 N-terminal Fragment
  63. 4n7z: Crystal Structure of Human Plk4 Cryptic Polo Box (cpb) in Complex with a Cep192 N-terminal Fragment
  64. 4n9j: Crystal Structure of The Cryptic Polo Box Domain of Human Plk4
  65. 4nk7: Crystal Structure of The D. Melanogaster Plk4 Cryptic Polo Box (cpb)
  66. 4o9w: Crystal Structure of Polo-like Kinase(plk1)pbd in Complex with Phospho Peptide
  67. 4rcp: Crystal Structure of Plk1 Polo-box Domain in Complex with Pl-2
  68. 4o6w: Peptide-based Inhibitors of Plk1 Polo-box Domain
  69. 4rs6: Crystal Structure of The C Domain of Polo like Kinase II in Homo Sapiens
  70. 4whh: A New Class of Peptidomimetics Targeting The Polo-box Domain of Polo- like Kinase 1
  71. 4whk: A New Class of Peptidomimetics Targeting The Polo-box Domain of Polo- like Kinase 1
  72. 4whl: A New Class of Peptidomimetics Targeting The Polo-box Domain of Polo- like Kinase 1
  73. 4o56: Structure of Plk1 in Complex with Peptide
  74. 4xb0: Structure of The Plk2 Polo-box Domain
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